Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8cas_p.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 8.A N VAL 58.A O no hydrogen 2.895 N/A VAL 9.A N TYR 87.A O no hydrogen 2.899 N/A VAL 10.A N LEU 56.A O no hydrogen 2.902 N/A ASN 11.A N PHE 85.A O no hydrogen 2.890 N/A ALA 13.A N GLY 54.A O no hydrogen 3.325 N/A LEU 24.A N LYS 20.A O no hydrogen 3.477 N/A LYS 25.A N VAL 21.A O no hydrogen 2.897 N/A LYS 26.A N PRO 22.A O no hydrogen 3.172 N/A ALA 27.A N VAL 23.A O no hydrogen 2.916 N/A LEU 28.A N LEU 24.A O no hydrogen 2.894 N/A THR 29.A N LYS 25.A O no hydrogen 2.895 N/A SER 30.A N LYS 26.A O no hydrogen 2.912 N/A LEU 31.A N ALA 27.A O no hydrogen 2.902 N/A PHE 32.A N LEU 28.A O no hydrogen 2.895 N/A GLY 36.A N PHE 32.A O no hydrogen 3.250 N/A VAL 39.A N GLU 59.A O no hydrogen 2.823 N/A ASN 40.A N GLU 59.A O no hydrogen 2.933 N/A GLU 42.A N PHE 57.A O no hydrogen 2.887 N/A ASP 46.A N LYS 51.A O no hydrogen 2.897 N/A GLY 50.A N ASP 46.A O no hydrogen 2.862 N/A THR 52.A N ILE 16.A O no hydrogen 2.876 N/A LYS 53.A N PRO 44.A O no hydrogen 3.265 N/A LEU 56.A N VAL 10.A O no hydrogen 2.914 N/A PHE 57.A N GLU 42.A O no hydrogen 2.915 N/A VAL 58.A N ILE 8.A O no hydrogen 2.894 N/A GLU 59.A N ASN 40.A O no hydrogen 2.878 N/A CYS 60.A N GLN 6.A O no hydrogen 3.372 N/A ALA 66.A N SER 62.A O no hydrogen 3.355 N/A LYS 67.A N MET 63.A O no hydrogen 2.907 N/A LYS 68.A N ASN 64.A O no hydrogen 2.896 N/A ILE 69.A N ASP 65.A O no hydrogen 2.913 N/A ILE 70.A N ALA 66.A O no hydrogen 3.195 N/A LYS 71.A N LYS 67.A O no hydrogen 2.897 N/A SER 72.A N LYS 68.A O no hydrogen 2.905 N/A PHE 73.A N ILE 69.A O no hydrogen 2.898 N/A HIS 74.A N ILE 70.A O no hydrogen 3.322 N/A GLY 75.A N LEU 84.A O no hydrogen 2.862 N/A ASP 79.A N HIS 82.A O no hydrogen 3.494 N/A LEU 84.A N LYS 76.A O no hydrogen 3.235 N/A PHE 85.A N ASN 11.A O no hydrogen 2.907 N/A TYR 87.A N VAL 9.A O no hydrogen 2.918 N/A ASP 91.A N THR 88.A O no hydrogen 3.109 N/A GLU 93.A N MET 89.A O no hydrogen 3.480 N/A ARG 94.A N LYS 90.A O no hydrogen 2.910 N/A TYR 95.A N ASP 91.A O no hydrogen 2.937 N/A LEU 102.A N PRO 98.A O no hydrogen 3.186 N/A LYS 103.A N SER 99.A O no hydrogen 3.117 N/A MET 107.A N SER 104.A O no hydrogen 3.197 N/A VAL 111.A N ASP 108.A O no hydrogen 3.410 N/A PHE 115.A N PHE 126.A O no hydrogen 2.890 N/A VAL 116.A N ALA 572.A O no hydrogen 2.699 N/A LEU 117.A N SER 124.A O no hydrogen 2.890 N/A GLN 118.A N ASN 570.A O no hydrogen 2.977 N/A ASP 119.A N LYS 122.A O no hydrogen 2.869 N/A LYS 122.A N ASP 119.A O no hydrogen 2.981 N/A THR 123.A N ARG 141.A O no hydrogen 2.915 N/A SER 124.A N LEU 117.A O no hydrogen 2.915 N/A VAL 125.A N GLU 139.A O no hydrogen 2.881 N/A PHE 126.A N PHE 115.A O no hydrogen 2.895 N/A TRP 127.A N SER 136.A O no hydrogen 2.598 N/A ASN 128.A N ASP 113.A O no hydrogen 2.743 N/A VAL 138.A N VAL 125.A O no hydrogen 2.548 N/A GLU 139.A N VAL 125.A O no hydrogen 3.341 N/A ARG 141.A N THR 123.A O no hydrogen 2.887 N/A ASN 143.A N VAL 121.A O no hydrogen 2.611 N/A THR 146.A N TYR 161.A O no hydrogen 2.530 N/A ARG 150.A N PHE 159.A O no hydrogen 2.914 N/A GLY 155.A N SER 152.A O no hydrogen 2.999 N/A LEU 158.A N TRP 169.A O no hydrogen 2.897 N/A PHE 159.A N ARG 150.A O no hydrogen 2.862 N/A SER 160.A N THR 167.A O no hydrogen 2.875 N/A HIS 162.A N GLY 165.A O no hydrogen 2.871 N/A VAL 166.A N PHE 180.A O no hydrogen 2.890 N/A THR 167.A N SER 160.A O no hydrogen 2.925 N/A ALA 168.A N ARG 178.A O no hydrogen 2.864 N/A TRP 169.A N LEU 158.A O no hydrogen 2.903 N/A GLY 170.A N ASP 175.A O no hydrogen 3.286 N/A ASP 175.A N GLY 170.A O no hydrogen 3.261 N/A LEU 177.A N ALA 168.A O no hydrogen 2.834 N/A PHE 180.A N VAL 166.A O no hydrogen 2.901 N/A HIS 182.A N GLN 164.A O no hydrogen 3.023 N/A ARG 186.A N PHE 200.A O no hydrogen 2.903 N/A ASN 187.A N PHE 200.A O no hydrogen 3.385 N/A SER 189.A N VAL 198.A O no hydrogen 2.478 N/A SER 191.A N TYR 196.A O no hydrogen 2.656 N/A GLU 194.A N SER 191.A O no hydrogen 3.236 N/A LEU 197.A N TRP 228.A O no hydrogen 2.875 N/A VAL 198.A N SER 189.A O no hydrogen 2.455 N/A THR 199.A N CYS 226.A O no hydrogen 2.890 N/A PHE 200.A N ASN 187.A O no hydrogen 2.795 N/A SER 201.A N GLN 224.A O no hydrogen 3.097 N/A THR 202.A N ASP 184.A O no hydrogen 3.260 N/A ILE 205.A N HIS 223.A O no hydrogen 2.972 N/A ASN 220.A N THR 217.A O no hydrogen 3.188 N/A GLU 221.A N LYS 218.A O no hydrogen 3.444 N/A GLY 222.A N ILE 205.A O no hydrogen 3.005 N/A HIS 223.A N ASN 220.A O no hydrogen 3.432 N/A GLN 224.A N PHE 239.A O no hydrogen 2.814 N/A LEU 225.A N PHE 239.A O no hydrogen 2.910 N/A CYS 226.A N THR 199.A O no hydrogen 2.901 N/A ILE 227.A N ALA 237.A O no hydrogen 2.887 N/A TRP 228.A N LEU 197.A O no hydrogen 2.893 N/A ASP 229.A N LEU 234.A O no hydrogen 2.850 N/A ILE 230.A N LYS 195.A O no hydrogen 3.323 N/A GLY 233.A N ASP 229.A O no hydrogen 3.154 N/A MET 236.A N ILE 227.A O no hydrogen 2.655 N/A ALA 237.A N ILE 227.A O no hydrogen 2.912 N/A PHE 239.A N LEU 225.A O no hydrogen 2.909 N/A ARG 253.A N ALA 262.A O no hydrogen 3.103 N/A SER 255.A N TYR 260.A O no hydrogen 3.115 N/A CYS 261.A N HIS 272.A O no hydrogen 2.951 N/A ALA 262.A N ARG 253.A O no hydrogen 3.019 N/A ARG 263.A N ILE 270.A O no hydrogen 2.896 N/A VAL 265.A N SER 268.A O no hydrogen 2.892 N/A ASP 267.A N VAL 265.A O no hydrogen 2.840 N/A SER 268.A N VAL 265.A O no hydrogen 3.361 N/A LEU 269.A N PRO 288.A O no hydrogen 2.875 N/A ILE 270.A N ARG 263.A O no hydrogen 2.897 N/A HIS 272.A N CYS 261.A O no hydrogen 2.554 N/A ASP 273.A N MET 279.A O no hydrogen 2.679 N/A ALA 274.A N LYS 259.A O no hydrogen 2.829 N/A LYS 276.A N ASP 273.A O no hydrogen 3.136 N/A MET 279.A N ASP 273.A O no hydrogen 3.227 N/A LEU 281.A N VAL 271.A O no hydrogen 2.948 N/A LYS 287.A N LYS 284.A O no hydrogen 3.351 N/A ILE 291.A N ASP 267.A O no hydrogen 3.102 N/A ARG 292.A N TRP 319.A O no hydrogen 2.970 N/A SER 295.A N ALA 317.A O no hydrogen 2.909 N/A VAL 301.A N SER 313.A O no hydrogen 3.295 N/A SER 313.A N VAL 301.A O no hydrogen 3.042 N/A LEU 316.A N ALA 333.A O no hydrogen 2.888 N/A ALA 317.A N SER 295.A O no hydrogen 2.901 N/A TYR 318.A N THR 331.A O no hydrogen 2.921 N/A TRP 319.A N ASP 293.A O no hydrogen 2.912 N/A THR 320.A N THR 329.A O no hydrogen 2.853 N/A THR 323.A N SER 326.A O no hydrogen 2.563 N/A THR 329.A N THR 320.A O no hydrogen 2.940 N/A ALA 330.A N VAL 344.A O no hydrogen 2.893 N/A THR 331.A N TYR 318.A O no hydrogen 2.900 N/A ILE 332.A N LYS 342.A O no hydrogen 2.964 N/A ALA 333.A N LEU 316.A O no hydrogen 2.940 N/A GLU 334.A N ARG 339.A O no hydrogen 3.287 N/A VAL 335.A N VAL 314.A O no hydrogen 2.986 N/A LEU 341.A N ILE 332.A O no hydrogen 2.875 N/A VAL 344.A N ALA 330.A O no hydrogen 2.876 N/A LEU 346.A N CYS 328.A O no hydrogen 2.882 N/A SER 350.A N GLU 368.A O no hydrogen 2.631 N/A THR 353.A N ASN 366.A O no hydrogen 2.906 N/A HIS 355.A N CYS 364.A O no hydrogen 2.913 N/A GLN 357.A N PHE 362.A O no hydrogen 2.942 N/A ALA 360.A N GLN 357.A O no hydrogen 3.206 N/A LEU 363.A N CYS 384.A O no hydrogen 2.937 N/A CYS 364.A N HIS 355.A O no hydrogen 2.898 N/A PHE 365.A N GLN 382.A O no hydrogen 2.895 N/A ASN 366.A N THR 353.A O no hydrogen 2.874 N/A VAL 367.A N ASN 380.A O no hydrogen 2.896 N/A GLU 368.A N ASN 351.A O no hydrogen 2.902 N/A ARG 369.A N PHE 378.A O no hydrogen 2.892 N/A HIS 370.A N GLN 348.A O no hydrogen 2.711 N/A PHE 378.A N ARG 369.A O no hydrogen 2.886 N/A SER 379.A N LEU 398.A O no hydrogen 2.932 N/A SER 379.A N ASP 400.A O no hydrogen 3.306 N/A ASN 380.A N VAL 367.A O no hydrogen 2.901 N/A LEU 381.A N VAL 396.A O no hydrogen 2.877 N/A GLN 382.A N PHE 365.A O no hydrogen 2.895 N/A ILE 383.A N GLU 394.A O no hydrogen 2.896 N/A CYS 384.A N LEU 363.A O no hydrogen 2.886 N/A ARG 385.A N PRO 392.A O no hydrogen 3.292 N/A LEU 386.A N GLU 361.A O no hydrogen 3.147 N/A GLU 388.A N ARG 385.A O no hydrogen 3.365 N/A GLU 394.A N ILE 383.A O no hydrogen 2.903 N/A VAL 396.A N LEU 381.A O no hydrogen 2.907 N/A LEU 398.A N SER 379.A O no hydrogen 2.888 N/A SER 401.A N VAL 419.A O no hydrogen 2.898 N/A PHE 403.A N ILE 417.A O no hydrogen 2.939 N/A GLU 404.A N ILE 417.A O no hydrogen 3.490 N/A GLY 406.A N VAL 415.A O no hydrogen 3.322 N/A PHE 414.A N TYR 437.A O no hydrogen 2.911 N/A THR 416.A N ARG 435.A O no hydrogen 2.905 N/A ILE 417.A N GLU 404.A O no hydrogen 3.263 N/A SER 418.A N THR 433.A O no hydrogen 2.905 N/A VAL 419.A N SER 401.A O no hydrogen 2.888 N/A ASN 432.A N THR 460.A O no hydrogen 2.436 N/A THR 433.A N SER 418.A O no hydrogen 2.883 N/A ILE 434.A N ILE 457.A O no hydrogen 2.891 N/A ARG 435.A N THR 416.A O no hydrogen 2.885 N/A PHE 436.A N LYS 455.A O no hydrogen 2.917 N/A TYR 437.A N PHE 414.A O no hydrogen 2.885 N/A ALA 438.A N SER 452.A O no hydrogen 2.798 N/A GLU 440.A N ARG 450.A O no hydrogen 2.799 N/A SER 452.A N ALA 438.A O no hydrogen 2.698 N/A VAL 454.A N PHE 436.A O no hydrogen 2.449 N/A ILE 457.A N ILE 434.A O no hydrogen 2.878 N/A THR 460.A N ASN 432.A O no hydrogen 2.709 N/A ASN 463.A N GLY 477.A O no hydrogen 3.240 N/A THR 464.A N GLY 477.A O no hydrogen 2.903 N/A SER 466.A N VAL 475.A O no hydrogen 2.899 N/A SER 468.A N PHE 473.A O no hydrogen 2.871 N/A GLY 471.A N SER 468.A O no hydrogen 3.314 N/A VAL 474.A N TYR 492.A O no hydrogen 2.897 N/A VAL 475.A N SER 466.A O no hydrogen 2.907 N/A VAL 476.A N GLN 490.A O no hydrogen 2.917 N/A GLY 477.A N THR 464.A O no hydrogen 2.903 N/A ALA 478.A N ASP 488.A O no hydrogen 2.869 N/A VAL 480.A N ALA 523.A O no hydrogen 2.749 N/A GLY 481.A N MET 484.A O no hydrogen 2.729 N/A SER 487.A N SER 521.A O no hydrogen 3.010 N/A ASP 488.A N ALA 478.A O no hydrogen 2.931 N/A GLN 490.A N VAL 476.A O no hydrogen 2.880 N/A PHE 491.A N ALA 516.A O no hydrogen 2.902 N/A TYR 492.A N VAL 474.A O no hydrogen 2.893 N/A ASP 493.A N LYS 513.A O no hydrogen 3.135 N/A MET 494.A N ARG 472.A O no hydrogen 3.304 N/A TYR 496.A N SER 511.A O no hydrogen 3.317 N/A GLY 498.A N TYR 496.A O no hydrogen 2.928 N/A ILE 502.A N LEU 512.A O no hydrogen 2.954 N/A ASP 504.A N VAL 454.A O no hydrogen 2.803 N/A ASN 505.A N VAL 454.A O no hydrogen 3.301 N/A SER 511.A N MET 494.A O no hydrogen 2.665 N/A VAL 515.A N PHE 491.A O no hydrogen 2.819 N/A THR 524.A N TRP 538.A O no hydrogen 3.136 N/A ASN 525.A N TRP 538.A O no hydrogen 2.919 N/A THR 527.A N THR 536.A O no hydrogen 2.924 N/A ASP 529.A N TYR 534.A O no hydrogen 2.897 N/A GLY 532.A N ASP 529.A O no hydrogen 3.135 N/A VAL 535.A N PHE 553.A O no hydrogen 2.912 N/A THR 536.A N THR 527.A O no hydrogen 2.857 N/A ALA 537.A N LYS 551.A O no hydrogen 2.884 N/A TRP 538.A N ASN 525.A O no hydrogen 2.857 N/A SER 539.A N GLY 549.A O no hydrogen 2.864 N/A SER 541.A N PHE 568.A O no hydrogen 2.865 N/A LYS 543.A N SER 540.A O no hydrogen 3.507 N/A GLU 547.A N LYS 545.A O no hydrogen 2.823 N/A GLY 549.A N SER 539.A O no hydrogen 2.933 N/A TYR 550.A N ASP 563.A O no hydrogen 2.887 N/A LYS 551.A N ALA 537.A O no hydrogen 2.910 N/A ILE 552.A N LYS 561.A O no hydrogen 2.869 N/A PHE 553.A N VAL 535.A O no hydrogen 2.875 N/A ASN 554.A N ASN 558.A O no hydrogen 3.037 N/A GLY 557.A N ASN 554.A O no hydrogen 3.328 N/A VAL 560.A N ILE 552.A O no hydrogen 2.718 N/A LYS 561.A N ILE 552.A O no hydrogen 3.261 N/A ASP 563.A N TYR 550.A O no hydrogen 2.909 N/A LYS 569.A N GLN 118.A O no hydrogen 2.900 N/A ALA 572.A N VAL 116.A O no hydrogen 3.150 N/A ARG 574.A N GLN 114.A O no hydrogen 2.543 N/A ARG 585.A N SER 581.A O no hydrogen 2.996 N/A LYS 586.A N ASN 582.A O no hydrogen 2.905 N/A LYS 587.A N ALA 583.A O no hydrogen 2.891 N/A VAL 588.A N GLU 584.A O no hydrogen 2.907 N/A ALA 604.A N GLU 600.A O no hydrogen 3.085 N/A MET 605.A N GLU 601.A O no hydrogen 3.389 N/A GLU 606.A N GLN 602.A O no hydrogen 2.926 N/A ALA 607.A N ASP 603.A O no hydrogen 2.884 N/A ASP 608.A N ALA 604.A O no hydrogen 2.904 N/A THR 609.A N MET 605.A O no hydrogen 3.241 N/A HIS 614.A N ASP 610.A O no hydrogen 3.032 N/A GLN 615.A N LEU 611.A O no hydrogen 2.905 N/A ARG 616.A N ILE 612.A O no hydrogen 2.915 N/A GLU 617.A N LEU 613.A O no hydrogen 2.902 N/A LEU 618.A N HIS 614.A O no hydrogen 2.888 N/A LEU 619.A N GLN 615.A O no hydrogen 2.907 N/A LYS 620.A N ARG 616.A O no hydrogen 2.921 N/A GLN 621.A N GLU 617.A O no hydrogen 2.890 N/A TRP 622.A N LEU 618.A O no hydrogen 2.891 N/A THR 623.A N LEU 619.A O no hydrogen 2.927 N/A GLU 624.A N LYS 620.A O no hydrogen 2.920 N/A TYR 625.A N GLN 621.A O no hydrogen 2.882 N/A ARG 626.A N TRP 622.A O no hydrogen 2.899 N/A GLU 627.A N THR 623.A O no hydrogen 2.933 N/A LYS 628.A N GLU 624.A O no hydrogen 2.905 N/A ILE 629.A N TYR 625.A O no hydrogen 2.889 N/A GLY 630.A N ARG 626.A O no hydrogen 2.917 N/A GLN 631.A N GLU 627.A O no hydrogen 2.921 N/A GLU 632.A N LYS 628.A O no hydrogen 2.899 N/A MET 633.A N ILE 629.A O no hydrogen 2.909 N/A GLU 634.A N GLY 630.A O no hydrogen 2.922 N/A LYS 635.A N GLN 631.A O no hydrogen 2.904 N/A SER 636.A N GLU 632.A O no hydrogen 2.897 N/A MET 637.A N MET 633.A O no hydrogen 2.920 N/A PHE 639.A N MET 633.A O no hydrogen 3.345 N/A