Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8cis_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 4.A N ILE 19.A O no hydrogen 2.795 N/A VAL 6.A N PHE 17.A O no hydrogen 2.747 N/A ARG 7.A N LEU 75.A O no hydrogen 2.740 N/A ARG 7.A NE.A GLU 16.A OE2 no hydrogen 2.887 N/A VAL 8.A N LEU 15.A O no hydrogen 2.912 N/A THR 9.A N PHE 77.A O no hydrogen 2.999 N/A THR 10.A N ALA 13.A O no hydrogen 2.819 N/A THR 10.A OG1 ASP 12.A OD1 no hydrogen 3.539 N/A THR 10.A OG1 ALA 13.A O no hydrogen 3.484 N/A ASP 12.A N THR 10.A OG1 no hydrogen 3.091 N/A ALA 13.A N THR 10.A OG1 no hydrogen 2.802 N/A LEU 15.A N VAL 8.A O no hydrogen 2.863 N/A PHE 17.A N VAL 6.A O no hydrogen 3.166 N/A ILE 19.A N ILE 4.A O no hydrogen 2.649 N/A THR 23.A N GLN 20.A O no hydrogen 3.002 N/A THR 23.A OG1 GLN 20.A O no hydrogen 2.606 N/A THR 24.A N GLN 27.A OE1 no hydrogen 3.026 N/A THR 24.A OG1 GLN 27.A OE1 no hydrogen 3.441 N/A GLY 25.A N LYS 62.A O no hydrogen 2.899 N/A LYS 26.A N LEU 60.A O no hydrogen 2.910 N/A LYS 26.A NZ ASP 30.A OD1 no hydrogen 2.918 N/A LYS 26.A NZ ASP 30.A OD2 no hydrogen 2.847 N/A GLN 27.A N THR 24.A OG1 no hydrogen 3.195 N/A LEU 28.A N THR 24.A O no hydrogen 3.042 N/A PHE 29.A N GLY 25.A O no hydrogen 2.849 N/A ASP 30.A N LYS 26.A O no hydrogen 2.866 N/A GLN 31.A N GLN 27.A O no hydrogen 3.127 N/A VAL 32.A N LEU 28.A O no hydrogen 3.120 N/A VAL 33.A N PHE 29.A O no hydrogen 3.012 N/A LYS 34.A N ASP 30.A O no hydrogen 3.074 N/A THR 35.A N GLN 31.A O no hydrogen 3.003 N/A THR 35.A OG1 GLN 31.A O no hydrogen 2.815 N/A ILE 36.A N VAL 32.A O no hydrogen 3.068 N/A GLY 37.A N VAL 33.A O no hydrogen 2.866 N/A GLY 37.A N LYS 34.A O no hydrogen 3.240 N/A LEU 38.A N VAL 33.A O no hydrogen 2.927 N/A PHE 44.A N VAL 41.A O no hydrogen 2.959 N/A GLY 45.A N ARG 80.A O no hydrogen 2.913 N/A GLN 47.A N LYS 78.A O no hydrogen 2.761 N/A TYR 48.A N THR 56.A O no hydrogen 2.802 N/A ASP 50.A N PHE 54.A O no hydrogen 2.878 N/A THR 51.A OG1 ASP 68.A OD1 no hydrogen 2.899 N/A GLY 53.A N ASP 50.A O no hydrogen 2.924 N/A PHE 54.A N ASP 50.A OD1 no hydrogen 2.825 N/A SER 55.A OG GLN 49.A OE1 no hydrogen 2.802 N/A THR 56.A N TYR 48.A O no hydrogen 2.808 N/A THR 56.A OG1 PHE 54.A O no hydrogen 3.032 N/A LEU 58.A N LEU 46.A O no hydrogen 2.766 N/A LYS 59.A N GLN 67.A OE1 no hydrogen 2.779 N/A VAL 64.A N THR 23.A O no hydrogen 3.017 N/A THR 65.A OG1 PRO 21.A O no hydrogen 3.430 N/A GLN 67.A N VAL 64.A O no hydrogen 3.262 N/A GLN 67.A NE2 LYS 59.A O no hydrogen 2.861 N/A GLN 67.A NE2 LYS 62.A O no hydrogen 3.360 N/A GLN 67.A NE2 LYS 63.A O no hydrogen 3.224 N/A VAL 69.A N GLN 67.A O no hydrogen 2.536 N/A ARG 70.A NE GLU 72.A OE1 no hydrogen 3.056 N/A LYS 71.A NZ VAL 69.A O no hydrogen 3.233 N/A LEU 75.A N SER 5.A O no hydrogen 2.965 N/A PHE 77.A N ARG 7.A O no hydrogen 2.820 N/A LYS 78.A N GLN 47.A O no hydrogen 2.852 N/A PHE 79.A N THR 9.A O no hydrogen 2.832 N/A ARG 80.A N GLY 45.A O no hydrogen 3.001 N/A ARG 80.A NH2 THR 9.A O no hydrogen 2.999 N/A ARG 80.A NH2 PHE 79.A O no hydrogen 2.943 N/A ALA 81.A N GLN 104.A OE1 no hydrogen 2.785 N/A LYS 82.A N PHE 43.A O no hydrogen 2.707 N/A PHE 83.A N PHE 43.A O no hydrogen 2.958 N/A ASP 87.A N GLU 91.A OE2 no hydrogen 3.042 N/A VAL 88.A N GLN 195.A OE1 no hydrogen 2.962 N/A GLU 90.A N ASP 87.A OD2 no hydrogen 2.924 N/A GLU 91.A N ASP 87.A O no hydrogen 3.082 N/A GLU 91.A N VAL 88.A O no hydrogen 3.346 N/A LEU 92.A N VAL 88.A O no hydrogen 2.964 N/A ILE 93.A N GLU 40.A OE2 no hydrogen 2.891 N/A GLN 94.A N GLU 40.A OE1 no hydrogen 2.888 N/A THR 97.A OG1 GLU 40.A OE1 no hydrogen 2.461 N/A GLN 98.A N GLN 94.A O no hydrogen 3.052 N/A GLN 98.A NE2 LEU 92.A O no hydrogen 2.895 N/A ARG 99.A N ASP 95.A O no hydrogen 2.873 N/A ARG 99.A NE ASP 12.A OD2 no hydrogen 3.324 N/A LEU 100.A N ILE 96.A O no hydrogen 2.902 N/A PHE 101.A N THR 97.A O no hydrogen 3.079 N/A PHE 102.A N GLN 98.A O no hydrogen 2.871 N/A LEU 103.A N ARG 99.A O no hydrogen 2.902 N/A GLN 104.A N LEU 100.A O no hydrogen 3.168 N/A GLN 104.A NE2 ALA 81.A O no hydrogen 2.999 N/A VAL 105.A N PHE 101.A O no hydrogen 2.844 N/A LYS 106.A N PHE 102.A O no hydrogen 2.826 N/A GLU 107.A N LEU 103.A O no hydrogen 2.931 N/A GLY 108.A N GLN 104.A O no hydrogen 3.189 N/A ILE 109.A N VAL 105.A O no hydrogen 2.964 N/A LEU 110.A N LYS 106.A O no hydrogen 2.865 N/A ASN 111.A N GLU 107.A O no hydrogen 2.866 N/A ASN 111.A ND2 ASP 113.A OD1 no hydrogen 3.459 N/A ASN 111.A ND2 ASP 113.A OD2 no hydrogen 2.809 N/A ASP 112.A N ILE 109.A O no hydrogen 3.133 N/A ASP 113.A N GLY 108.A O no hydrogen 2.815 N/A ILE 114.A N GLY 108.A O no hydrogen 3.048 N/A CYS 116.A SG.A PRO 117.A O no hydrogen 3.688 N/A CYS 116.A SG.B PRO 117.A O no hydrogen 3.903 N/A ALA 121.A N PRO 117.A O no hydrogen 2.946 N/A VAL 122.A N PRO 118.A O no hydrogen 2.978 N/A LEU 123.A N GLU 119.A O no hydrogen 2.975 N/A LEU 124.A N THR 120.A O no hydrogen 2.799 N/A ALA 125.A N ALA 121.A O no hydrogen 2.853 N/A SER 126.A N VAL 122.A O no hydrogen 2.962 N/A SER 126.A OG LEU 123.A O no hydrogen 2.674 N/A SER 126.A OG HIS 178.A NE2 no hydrogen 2.705 N/A TYR 127.A N LEU 123.A O no hydrogen 3.289 N/A ALA 128.A N LEU 124.A O no hydrogen 3.005 N/A VAL 129.A N ALA 125.A O no hydrogen 2.896 N/A GLN 130.A N SER 126.A O no hydrogen 3.058 N/A GLN 130.A NE2 ASP 135.A OD1 no hydrogen 2.993 N/A GLN 130.A NE2 MET 181.A O no hydrogen 3.004 N/A SER 131.A N TYR 127.A O no hydrogen 2.921 N/A LYS 132.A N ALA 128.A O no hydrogen 2.986 N/A TYR 133.A N VAL 129.A O no hydrogen 2.810 N/A TYR 133.A OH ASP 149.A OD1 no hydrogen 2.999 N/A TYR 133.A OH ASP 149.A OD2 no hydrogen 2.516 N/A GLY 134.A N GLN 130.A O no hydrogen 2.976 N/A ASN 137.A N HIS 141.A ND1 no hydrogen 2.763 N/A GLU 139.A N ASN 137.A OD1 no hydrogen 3.272 N/A VAL 140.A N ASN 137.A O no hydrogen 2.947 N/A HIS 141.A N ASN 137.A O no hydrogen 2.591 N/A LYS 142.A N VAL 140.A O no hydrogen 2.903 N/A LYS 142.A NZ LYS 138.A O no hydrogen 3.214 N/A LYS 142.A NZ GLU 139.A O no hydrogen 3.161 N/A GLY 144.A N GLU 168.A OE2 no hydrogen 3.000 N/A TYR 145.A N LYS 142.A O no hydrogen 2.954 N/A TYR 145.A OH HIS 175.A ND1 no hydrogen 2.751 N/A LEU 146.A N GLU 168.A OE1 no hydrogen 3.057 N/A ALA 147.A N GLY 144.A O no hydrogen 2.991 N/A ASP 149.A N LEU 146.A O no hydrogen 3.110 N/A ARG 155.A N ASP 112.A OD1 no hydrogen 3.431 N/A ARG 155.A NH1 CYS 116.A O no hydrogen 2.727 N/A ARG 155.A NH2 CYS 116.A O no hydrogen 2.846 N/A LEU 157.A N PRO 153.A O no hydrogen 3.252 N/A GLU 158.A N GLN 154.A O no hydrogen 2.544 N/A GLN 159.A N ARG 155.A O no hydrogen 2.942 N/A ASN 163.A N GLN 166.A OE1 no hydrogen 2.788 N/A LYS 164.A N ASN 163.A OD1.B no hydrogen 3.004 N/A GLN 166.A N ASN 163.A OD1.A no hydrogen 2.759 N/A TRP 167.A N ASN 163.A O no hydrogen 3.109 N/A GLU 168.A N LYS 164.A O no hydrogen 3.066 N/A GLU 169.A N ASP 165.A O no hydrogen 3.106 N/A ARG 170.A N GLN 166.A O no hydrogen 3.047 N/A ARG 170.A NH1.B GLU 119.A OE1 no hydrogen 2.672 N/A ARG 170.A NH2.A GLU 119.A OE1 no hydrogen 3.000 N/A ILE 171.A N TRP 167.A O no hydrogen 3.175 N/A GLN 172.A N GLU 168.A O no hydrogen 2.740 N/A GLN 172.A NE2.B GLU 176.A OE1.A no hydrogen 2.792 N/A VAL 173.A N GLU 169.A O no hydrogen 3.242 N/A HIS 175.A N ILE 171.A O no hydrogen 2.884 N/A HIS 175.A ND1 TYR 145.A OH no hydrogen 2.751 N/A HIS 175.A NE2 GLY 134.A O no hydrogen 2.773 N/A GLU 176.A N GLN 172.A O no hydrogen 2.910 N/A GLU 177.A N VAL 173.A O no hydrogen 3.264 N/A HIS 178.A N HIS 175.A O no hydrogen 3.025 N/A HIS 178.A NE2 SER 126.A OG no hydrogen 2.705 N/A ARG 179.A N GLU 176.A O no hydrogen 3.301 N/A ARG 179.A NE GLU 176.A OE2.B no hydrogen 3.497 N/A ARG 179.A NH1 PHE 136.A O no hydrogen 2.945 N/A ARG 179.A NH2 PHE 136.A O no hydrogen 2.722 N/A ARG 179.A NH2 GLU 176.A OE2.B no hydrogen 3.326 N/A GLY 180.A N ASP 135.A OD1 no hydrogen 2.819 N/A MET 181.A N HIS 178.A O no hydrogen 2.899 N/A ARG 183.A NE SER 131.A O no hydrogen 3.135 N/A ARG 183.A NH2 LYS 132.A O no hydrogen 3.496 N/A ASP 185.A N LEU 182.A O no hydrogen 2.899 N/A ALA 186.A N LEU 182.A O no hydrogen 3.019 N/A VAL 187.A N ARG 183.A O no hydrogen 3.170 N/A LEU 188.A N GLU 184.A O no hydrogen 3.132 N/A GLU 189.A N ASP 185.A O no hydrogen 2.893 N/A TYR 190.A N ALA 186.A O no hydrogen 2.958 N/A LEU 191.A N VAL 187.A O no hydrogen 3.080 N/A LYS 192.A N LEU 188.A O no hydrogen 2.844 N/A LYS 192.A NZ GLU 189.A OE1 no hydrogen 3.121 N/A ILE 193.A N GLU 189.A O no hydrogen 3.164 N/A ALA 194.A N TYR 190.A O no hydrogen 2.930 N/A GLN 195.A N LEU 191.A O no hydrogen 2.890 N/A GLN 195.A NE2 ASP 87.A OD1 no hydrogen 3.112 N/A ASP 196.A N ILE 193.A O no hydrogen 3.166 N/A LEU 197.A N ALA 194.A O no hydrogen 2.983 N/A TYR 200.A N LEU 197.A O no hydrogen 3.045 N/A VAL 202.A N MET 199.A O no hydrogen 3.350 N/A ASN 203.A N VAL 219.A O no hydrogen 3.010 N/A ASN 203.A ND2 VAL 219.A O no hydrogen 2.963 N/A TYR 204.A OH ARG 232.A O no hydrogen 2.675 N/A PHE 205.A N LEU 217.A O no hydrogen 2.841 N/A ILE 207.A N LEU 215.A O no hydrogen 3.081 N/A LYS 208.A N TYR 269.A O no hydrogen 2.932 N/A ASN 209.A N SER 213.A O no hydrogen 3.032 N/A LYS 211.A N ASN 209.A OD1 no hydrogen 2.917 N/A GLY 212.A N ASN 209.A O no hydrogen 2.849 N/A SER 213.A N ASN 209.A OD1 no hydrogen 2.925 N/A LEU 215.A N ILE 207.A O no hydrogen 2.882 N/A TRP 216.A N TYR 227.A O no hydrogen 2.959 N/A TRP 216.A NE1 GLN 229.A O no hydrogen 2.886 N/A LEU 217.A N PHE 205.A O no hydrogen 2.864 N/A GLY 218.A N ASN 225.A O no hydrogen 2.782 N/A VAL 219.A N ASN 203.A O no hydrogen 2.896 N/A ASP 220.A N GLY 223.A O no hydrogen 2.958 N/A LEU 222.A N ASP 220.A OD1 no hydrogen 3.030 N/A GLY 223.A N ASP 220.A O no hydrogen 3.308 N/A GLY 223.A N ASP 220.A OD1 no hydrogen 3.265 N/A LEU 224.A N PHE 239.A O no hydrogen 2.985 N/A ASN 225.A N GLY 218.A O no hydrogen 2.857 N/A ILE 226.A N ILE 237.A O no hydrogen 2.863 N/A TYR 227.A N TRP 216.A O no hydrogen 2.811 N/A ASP 231.A N GLU 228.A O no hydrogen 3.134 N/A LEU 233.A N ASP 231.A OD1 no hydrogen 2.824 N/A THR 234.A N ASP 231.A OD1 no hydrogen 3.124 N/A ILE 237.A N ILE 226.A O no hydrogen 3.308 N/A PHE 239.A N LEU 224.A O no hydrogen 2.735 N/A TRP 241.A N LEU 222.A O no hydrogen 3.248 N/A TRP 241.A NE1 ALA 221.A O no hydrogen 2.941 N/A GLU 243.A N PRO 240.A O no hydrogen 2.891 N/A ILE 244.A N TRP 241.A O no hydrogen 2.967 N/A ARG 245.A N LYS 257.A O no hydrogen 2.857 N/A ASN 246.A N LYS 257.A O no hydrogen 3.417 N/A SER 248.A N VAL 255.A O no hydrogen 2.909 N/A SER 248.A OG ASN 246.A OD1 no hydrogen 2.825 N/A ASN 250.A N LYS 253.A O no hydrogen 2.906 N/A LYS 252.A NZ PRO 271.A O no hydrogen 3.551 N/A LYS 253.A N ASN 250.A O no hydrogen 2.858 N/A PHE 254.A N PHE 268.A O no hydrogen 2.892 N/A VAL 255.A N SER 248.A O no hydrogen 2.900 N/A ILE 256.A N PHE 266.A O no hydrogen 2.862 N/A LYS 257.A N ASN 246.A O no hydrogen 2.985 N/A ILE 259.A N GLU 243.A O no hydrogen 3.102 N/A LYS 262.A N ASP 260.A OD1 no hydrogen 3.201 N/A ALA 263.A N ASP 260.A O no hydrogen 2.858 N/A PHE 266.A N ILE 256.A O no hydrogen 2.990 N/A PHE 268.A N PHE 254.A O no hydrogen 2.967 N/A TYR 269.A N LYS 208.A O no hydrogen 2.763 N/A ALA 270.A N LYS 252.A O no hydrogen 2.830 N/A ILE 275.A N ARG 272.A O no hydrogen 3.102 N/A ASN 276.A N ARG 272.A O no hydrogen 3.162 N/A ASN 276.A ND2 ASP 251.A O no hydrogen 2.889 N/A ASN 276.A ND2 LYS 253.A O no hydrogen 2.888 N/A LYS 277.A N LEU 273.A O no hydrogen 2.996 N/A ARG 278.A N ARG 274.A O no hydrogen 3.005 N/A ARG 278.A NH1.B SER 55.A O no hydrogen 2.829 N/A ARG 278.A NH2.B SER 55.A O no hydrogen 3.376 N/A ILE 279.A N ILE 275.A O no hydrogen 2.880 N/A LEU 280.A N ASN 276.A O no hydrogen 3.086 N/A ALA 281.A N LYS 277.A O no hydrogen 3.104 N/A LEU 282.A N ARG 278.A O no hydrogen 3.007 N/A CYS 283.A N ILE 279.A O no hydrogen 2.987 N/A CYS 283.A SG ILE 279.A O no hydrogen 3.333 N/A MET 284.A N LEU 280.A O no hydrogen 2.868 N/A GLY 285.A N ALA 281.A O no hydrogen 2.987 N/A ASN 286.A N LEU 282.A O no hydrogen 3.033 N/A ASN 286.A ND2 LEU 282.A O no hydrogen 3.100 N/A HIS 287.A N CYS 283.A O no hydrogen 2.907 N/A GLU 288.A N MET 284.A O no hydrogen 2.933 N/A LEU 289.A N GLY 285.A O no hydrogen 3.153 N/A TYR 290.A N ASN 286.A O no hydrogen 2.913 N/A MET 291.A N HIS 287.A O no hydrogen 3.063 N/A ARG 292.A N GLU 288.A O no hydrogen 2.906 N/A ARG 293.A N LEU 289.A O no hydrogen 2.886 N/A ARG 293.A NE GLU 91.A OE1 no hydrogen 2.766 N/A ARG 293.A NH1 GLU 86.A OE1 no hydrogen 2.863 N/A ARG 294.A N MET 291.A O no hydrogen 3.325 N/A ARG 294.A NH1 GLU 86.A OE1 no hydrogen 3.460 N/A ARG 294.A NH1 GLU 86.A OE2 no hydrogen 2.685 N/A ARG 294.A NH2 GLU 86.A OE1 no hydrogen 2.836 N/A ARG 294.A NH2 GLU 86.A OE2 no hydrogen 3.421 N/A ARG 294.A NH2 TYR 290.A O no hydrogen 3.069 N/A LYS 295.A N ARG 292.A O no hydrogen 3.045 N/A VAL 301.A N THR 298.A OG1 no hydrogen 3.115 N/A GLN 302.A N THR 298.A O no hydrogen 2.868 N/A GLN 302.A NE2 ASP 297.A O no hydrogen 2.613 N/A GLN 303.A N ILE 299.A O no hydrogen 2.940 N/A MET 304.A N GLU 300.A O no hydrogen 2.930 N/A LYS 305.A N VAL 301.A O no hydrogen 2.999 N/A LYS 305.A NZ GLU 90.A O no hydrogen 3.502 N/A LYS 305.A NZ ASP 297.A OD1 no hydrogen 3.555 N/A LYS 305.A NZ ASP 297.A OD2 no hydrogen 2.754 N/A ALA 306.A N GLN 302.A O no hydrogen 3.169 N/A GLN 307.A N GLN 303.A O no hydrogen 2.786 N/A ALA 308.A N MET 304.A O no hydrogen 3.040 N/A ARG 309.A N LYS 305.A O no hydrogen 3.166 N/A GLU 310.A N ALA 306.A O no hydrogen 2.998 N/A GLU 311.A N ALA 308.A O no hydrogen 3.255 N/A