Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8cjo_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 7.A N ASP 11.A OD2 no hydrogen 2.859 N/A ASP 11.A N LYS 8.A O no hydrogen 3.026 N/A LEU 12.A N ILE 9.A O no hydrogen 3.259 N/A ASP 13.A N SER 10.A O no hydrogen 2.965 N/A HIS 14.A N ASP 11.A O no hydrogen 3.073 N/A CYS 15.A N LEU 12.A O no hydrogen 3.238 N/A CYS 15.A SG LEU 12.A O no hydrogen 3.720 N/A ALA 16.A N LEU 12.A O no hydrogen 2.913 N/A ASN 17.A ND2 MET 47.A O no hydrogen 2.673 N/A ARG 18.A N CYS 15.A O no hydrogen 2.826 N/A ARG 18.A NH1 ASP 134.A OD1 no hydrogen 3.135 N/A ARG 18.A NH1 ASP 134.A OD2 no hydrogen 3.399 N/A LEU 20.A N TYR 129.A O no hydrogen 3.188 N/A TYR 22.A OH HIS 27.A ND1 no hydrogen 2.667 N/A GLY 23.A N ASP 24.A OD2 no hydrogen 3.125 N/A HIS 27.A N ASP 24.A O no hydrogen 3.006 N/A HIS 27.A NE2 GLU 161.A OE1 no hydrogen 2.783 N/A GLY 29.A N HIS 27.A ND1 no hydrogen 3.201 N/A PHE 30.A N HIS 27.A O no hydrogen 3.041 N/A ASP 32.A N GLY 29.A O no hydrogen 3.025 N/A TYR 35.A N ASP 32.A OD1 no hydrogen 3.044 N/A TYR 35.A OH VAL 150.A O no hydrogen 2.835 N/A ARG 36.A N ASP 32.A O no hydrogen 2.951 N/A ARG 36.A NH1 PHE 30.A O no hydrogen 3.105 N/A LYS 37.A N ASN 33.A O no hydrogen 3.058 N/A LYS 37.A NZ ASN 33.A OD1 no hydrogen 2.866 N/A ARG 38.A N VAL 34.A O no hydrogen 2.979 N/A ARG 38.A NE GLU 64.A OE2 no hydrogen 2.888 N/A ARG 38.A NH2 GLU 59.A O no hydrogen 3.051 N/A ARG 38.A NH2 GLU 64.A OE1 no hydrogen 2.857 N/A ARG 39.A N TYR 35.A O no hydrogen 2.818 N/A ARG 39.A NH1 TYR 35.A OH no hydrogen 3.124 N/A ARG 39.A NH1 GLU 161.A OE1 no hydrogen 3.303 N/A ARG 39.A NH1 GLU 161.A OE2 no hydrogen 3.317 N/A ARG 39.A NH2 GLU 161.A OE2 no hydrogen 2.718 N/A LYS 40.A N ARG 36.A O no hydrogen 3.041 N/A LYS 40.A NZ ASP 44.A OD1 no hydrogen 3.369 N/A LYS 40.A NZ ASP 44.A OD2 no hydrogen 2.775 N/A TYR 41.A N LYS 37.A O no hydrogen 2.933 N/A PHE 42.A N ARG 38.A O no hydrogen 2.981 N/A ALA 43.A N ARG 39.A O no hydrogen 2.880 N/A ASP 44.A N LYS 40.A O no hydrogen 2.924 N/A LEU 45.A N TYR 41.A O no hydrogen 3.214 N/A ALA 46.A N PHE 42.A O no hydrogen 3.174 N/A MET 47.A N ALA 43.A O no hydrogen 2.918 N/A ASN 48.A N ASP 44.A O no hydrogen 2.971 N/A TYR 49.A N LEU 45.A O no hydrogen 3.156 N/A TYR 49.A N ALA 46.A O no hydrogen 3.291 N/A LYS 50.A N ASP 53.A OD2 no hydrogen 3.014 N/A HIS 51.A N ASP 13.A OD1 no hydrogen 2.869 N/A ASP 53.A N LYS 50.A O no hydrogen 2.983 N/A ILE 55.A N GLU 109.A OE1 no hydrogen 2.721 N/A LYS 57.A NZ ASP 110.A OD1 no hydrogen 2.941 N/A VAL 58.A N GLN 107.A OE1 no hydrogen 2.903 N/A THR 61.A N GLU 64.A OE1 no hydrogen 2.851 N/A GLU 64.A N THR 61.A OG1 no hydrogen 3.121 N/A ILE 65.A N THR 61.A O no hydrogen 2.906 N/A LYS 66.A N GLU 62.A O no hydrogen 2.994 N/A THR 67.A N GLU 63.A O no hydrogen 3.124 N/A THR 67.A OG1 GLU 63.A O no hydrogen 3.100 N/A TRP 68.A N GLU 64.A O no hydrogen 3.035 N/A TRP 68.A NE1 ARG 101.A O no hydrogen 2.888 N/A GLY 69.A N ILE 65.A O no hydrogen 2.869 N/A THR 70.A N LYS 66.A O no hydrogen 2.902 N/A THR 70.A OG1 LYS 66.A O no hydrogen 2.977 N/A VAL 71.A N THR 67.A O no hydrogen 3.148 N/A PHE 72.A N TRP 68.A O no hydrogen 2.708 N/A GLN 73.A N GLY 69.A O no hydrogen 2.868 N/A GLN 73.A NE2 GLU 102.A OE2 no hydrogen 2.917 N/A GLU 74.A N THR 70.A O no hydrogen 3.342 N/A LEU 75.A N VAL 71.A O no hydrogen 3.122 N/A ASN 76.A N PHE 72.A O no hydrogen 3.170 N/A ASN 76.A ND2 PHE 72.A O no hydrogen 2.744 N/A LYS 77.A N GLU 74.A O no hydrogen 3.204 N/A LYS 77.A NZ GLU 74.A OE1 no hydrogen 3.257 N/A LYS 77.A NZ GLU 74.A OE2 no hydrogen 3.251 N/A LEU 78.A N LEU 75.A O no hydrogen 2.818 N/A TYR 79.A N LEU 75.A O no hydrogen 2.972 N/A TYR 79.A OH LEU 229.A O no hydrogen 2.802 N/A THR 81.A N LEU 78.A O no hydrogen 3.108 N/A THR 81.A OG1 LEU 78.A O no hydrogen 3.166 N/A THR 81.A OG1 HIS 82.A ND1 no hydrogen 2.939 N/A HIS 82.A N LEU 78.A O no hydrogen 3.005 N/A HIS 82.A N TYR 79.A O no hydrogen 3.160 N/A HIS 82.A ND1 THR 81.A OG1 no hydrogen 2.939 N/A ALA 83.A N TYR 79.A O no hydrogen 2.825 N/A CYS 84.A N VAL 223.A O no hydrogen 3.019 N/A CYS 84.A SG GLU 86.A OE1 no hydrogen 3.474 N/A CYS 84.A SG VAL 223.A O no hydrogen 3.729 N/A ARG 85.A N GLN 217.A OE1 no hydrogen 2.929 N/A GLU 86.A N GLU 86.A OE1 no hydrogen 2.641 N/A TYR 87.A OH LEU 169.A O no hydrogen 2.491 N/A LEU 88.A N CYS 84.A O no hydrogen 3.200 N/A LYS 89.A N ARG 85.A O no hydrogen 2.918 N/A LYS 89.A NZ ASN 90.A OD1 no hydrogen 2.993 N/A LYS 89.A NZ GLU 177.A OE1 no hydrogen 3.179 N/A ASN 90.A N GLU 86.A O no hydrogen 3.157 N/A ASN 90.A ND2 PRO 173.A O no hydrogen 2.994 N/A ASN 90.A ND2 GLU 177.A OE1 no hydrogen 3.258 N/A LEU 91.A N TYR 87.A O no hydrogen 2.994 N/A LEU 94.A N ASN 90.A O no hydrogen 3.199 N/A SER 95.A N LEU 91.A O no hydrogen 3.059 N/A SER 95.A OG TYR 100.A O no hydrogen 3.340 N/A LYS 96.A N PRO 92.A O no hydrogen 3.017 N/A TYR 97.A N LEU 93.A O no hydrogen 2.868 N/A CYS 98.A N LEU 94.A O no hydrogen 2.783 N/A CYS 98.A SG ASP 110.A O no hydrogen 3.713 N/A TYR 100.A OH LEU 168.A O no hydrogen 2.637 N/A ARG 101.A NE ASP 103.A OD1 no hydrogen 3.201 N/A ASN 104.A N ARG 101.A O no hydrogen 3.081 N/A ASN 104.A ND2 GLY 99.A O no hydrogen 2.790 N/A GLN 107.A NE2 VAL 58.A O no hydrogen 2.742 N/A VAL 111.A N GLN 107.A O no hydrogen 3.143 N/A SER 112.A N LEU 108.A O no hydrogen 2.759 N/A ASN 113.A N GLU 109.A O no hydrogen 3.080 N/A ASN 113.A ND2 GLU 109.A OE2 no hydrogen 3.448 N/A PHE 114.A N ASP 110.A O no hydrogen 3.038 N/A LEU 115.A N VAL 111.A O no hydrogen 2.959 N/A LYS 116.A N SER 112.A O no hydrogen 2.889 N/A GLU 117.A N ASN 113.A O no hydrogen 3.214 N/A ARG 118.A N PHE 114.A O no hydrogen 3.081 N/A THR 119.A N LEU 115.A O no hydrogen 2.895 N/A THR 119.A OG1 LEU 175.A O no hydrogen 2.771 N/A GLY 120.A N LEU 115.A O no hydrogen 3.046 N/A GLY 120.A N LYS 116.A O no hydrogen 3.096 N/A PHE 121.A N THR 119.A OG1 no hydrogen 3.377 N/A SER 122.A N ARG 142.A O no hydrogen 2.842 N/A ILE 123.A N SER 112.A OG no hydrogen 2.843 N/A ARG 124.A N PHE 144.A O no hydrogen 3.181 N/A ARG 124.A NH1 ASP 13.A OD1 no hydrogen 2.773 N/A ARG 124.A NH2 ASP 13.A OD1 no hydrogen 2.938 N/A VAL 126.A N CYS 146.A O no hydrogen 2.833 N/A TYR 129.A N LEU 20.A O no hydrogen 3.287 N/A ARG 133.A NH1 ALA 194.A O no hydrogen 2.771 N/A ARG 133.A NH2 ALA 194.A O no hydrogen 3.020 N/A ARG 133.A NH2 GLU 196.A OE1 no hydrogen 2.766 N/A ASP 134.A N SER 131.A OG no hydrogen 3.065 N/A PHE 135.A N SER 131.A O no hydrogen 2.838 N/A LEU 136.A N PRO 132.A O no hydrogen 2.841 N/A SER 137.A N ARG 133.A O no hydrogen 2.991 N/A SER 137.A OG ASP 134.A O no hydrogen 2.816 N/A GLY 138.A N ASP 134.A O no hydrogen 3.262 N/A GLY 138.A N PHE 135.A O no hydrogen 3.180 N/A ALA 140.A N SER 137.A O no hydrogen 3.155 N/A PHE 141.A N GLY 138.A O no hydrogen 2.956 N/A ARG 142.A N LEU 139.A O no hydrogen 2.880 N/A ARG 142.A NE GLN 185.A OE1 no hydrogen 2.866 N/A ARG 142.A NH1 THR 119.A O no hydrogen 2.817 N/A ARG 142.A NH2 GLN 185.A OE1 no hydrogen 3.075 N/A VAL 143.A N GLY 138.A O no hydrogen 2.886 N/A PHE 144.A N SER 122.A O no hydrogen 2.910 N/A CYS 146.A N ARG 124.A O no hydrogen 2.903 N/A CYS 146.A SG.A PHE 144.A O no hydrogen 3.813 N/A CYS 146.A SG.B THR 147.A O no hydrogen 3.457 N/A THR 147.A N GLU 167.A OE1 no hydrogen 2.888 N/A THR 147.A OG1 GLU 167.A OE1 no hydrogen 2.980 N/A GLN 148.A NE2 PRO 56.A O no hydrogen 3.003 N/A TYR 149.A OH PRO 162.A O no hydrogen 2.672 N/A ARG 151.A N ASP 163.A OD2 no hydrogen 2.754 N/A ARG 151.A NE ASP 163.A OD2 no hydrogen 2.795 N/A ARG 151.A NH1 PRO 156.A O no hydrogen 2.832 N/A ARG 151.A NH2 ASP 163.A OD1 no hydrogen 2.873 N/A HIS 152.A ND1 SER 154.A OG no hydrogen 2.854 N/A HIS 152.A NE2 ASP 32.A OD2 no hydrogen 2.892 N/A SER 153.A OG GLU 63.A OE2 no hydrogen 2.283 N/A SER 154.A N HIS 152.A ND1 no hydrogen 3.298 N/A SER 154.A OG HIS 152.A ND1 no hydrogen 2.854 N/A ASP 155.A N HIS 152.A O no hydrogen 3.420 N/A PHE 157.A N ASP 155.A OD1 no hydrogen 3.102 N/A TYR 158.A N ASP 155.A O no hydrogen 3.110 N/A THR 164.A N TYR 149.A O no hydrogen 2.867 N/A THR 164.A OG1 THR 147.A O no hydrogen 3.043 N/A CYS 165.A SG ASP 163.A OD2 no hydrogen 3.521 N/A HIS 166.A N ASP 163.A OD1 no hydrogen 3.147 N/A HIS 166.A ND1 SER 230.A OG no hydrogen 2.767 N/A HIS 166.A NE2 HIS 171.A NE2 no hydrogen 3.061 N/A GLU 167.A N ASP 163.A O no hydrogen 3.190 N/A LEU 168.A N THR 164.A O no hydrogen 2.859 N/A LEU 169.A N CYS 165.A O no hydrogen 2.954 N/A GLY 170.A N HIS 166.A O no hydrogen 2.850 N/A HIS 171.A N GLU 167.A O no hydrogen 3.086 N/A VAL 172.A N GLU 167.A O no hydrogen 3.095 N/A LEU 175.A N HIS 171.A O no hydrogen 3.175 N/A ALA 176.A N VAL 172.A O no hydrogen 3.305 N/A GLU 177.A N LEU 174.A O no hydrogen 2.843 N/A ALA 181.A N GLU 177.A O no hydrogen 2.828 N/A GLN 182.A N PRO 178.A O no hydrogen 2.974 N/A GLN 182.A NE2 GLU 186.A OE2 no hydrogen 2.862 N/A PHE 183.A N SER 179.A O no hydrogen 3.107 N/A SER 184.A N PHE 180.A O no hydrogen 2.936 N/A SER 184.A OG PHE 180.A O no hydrogen 3.031 N/A GLN 185.A N ALA 181.A O no hydrogen 2.914 N/A GLN 185.A NE2 ALA 140.A O no hydrogen 2.931 N/A GLU 186.A N GLN 182.A O no hydrogen 2.997 N/A ILE 187.A N PHE 183.A O no hydrogen 3.282 N/A GLY 188.A N SER 184.A O no hydrogen 3.218 N/A LEU 189.A N GLN 185.A O no hydrogen 2.753 N/A ALA 190.A N GLU 186.A O no hydrogen 3.042 N/A SER 191.A N ILE 187.A O no hydrogen 3.110 N/A SER 191.A N GLY 188.A O no hydrogen 3.109 N/A SER 191.A OG GLY 188.A O no hydrogen 2.704 N/A LEU 192.A N LEU 189.A O no hydrogen 3.347 N/A ALA 194.A N SER 191.A O no hydrogen 2.969 N/A ALA 198.A N SER 195.A OG no hydrogen 2.995 N/A VAL 199.A N SER 195.A O no hydrogen 2.890 N/A GLN 200.A N GLU 196.A O no hydrogen 2.918 N/A GLN 200.A NE2 THR 204.A OG1 no hydrogen 3.288 N/A GLN 200.A NE2 CYS 254.A O no hydrogen 3.018 N/A LYS 201.A N GLU 197.A O no hydrogen 2.967 N/A LEU 202.A N ALA 198.A O no hydrogen 2.873 N/A ALA 203.A N VAL 199.A O no hydrogen 2.840 N/A THR 204.A N GLN 200.A O no hydrogen 3.016 N/A THR 204.A OG1 GLN 200.A O no hydrogen 3.004 N/A CYS 205.A N LYS 201.A O no hydrogen 3.016 N/A CYS 205.A SG LYS 201.A O no hydrogen 3.415 N/A CYS 205.A SG PRO 250.A O no hydrogen 4.045 N/A TYR 206.A N LEU 202.A O no hydrogen 2.864 N/A TYR 206.A OH GLU 211.A OE2 no hydrogen 2.665 N/A PHE 207.A N ALA 203.A O no hydrogen 2.888 N/A PHE 208.A N THR 204.A O no hydrogen 3.049 N/A THR 209.A N TYR 206.A O no hydrogen 3.163 N/A THR 209.A OG1 CYS 205.A O no hydrogen 2.743 N/A THR 209.A OG1 TYR 206.A O no hydrogen 3.317 N/A GLU 211.A N TYR 206.A O no hydrogen 3.321 N/A PHE 212.A N PHE 207.A O no hydrogen 2.836 N/A GLY 213.A N THR 209.A O no hydrogen 2.814 N/A LEU 214.A N PHE 268.A O no hydrogen 3.055 N/A CYS 215.A N ARG 222.A O no hydrogen 2.843 N/A LYS 216.A N SER 270.A O no hydrogen 3.265 N/A LYS 216.A NZ GLU 271.A OE2 no hydrogen 3.175 N/A GLN 217.A N GLN 220.A O no hydrogen 2.771 N/A GLN 217.A NE2 GLU 86.A OE1 no hydrogen 2.831 N/A GLN 220.A N GLN 217.A O no hydrogen 3.121 N/A ARG 222.A N CYS 215.A O no hydrogen 2.767 N/A ARG 222.A NH1 ALA 83.A O no hydrogen 2.974 N/A VAL 223.A N HIS 82.A O no hydrogen 2.844 N/A PHE 224.A N GLY 213.A O no hydrogen 3.023 N/A GLY 225.A N GLY 213.A O no hydrogen 2.996 N/A ALA 226.A N VAL 210.A O no hydrogen 2.880 N/A GLY 227.A N GLU 211.A O no hydrogen 2.697 N/A LEU 229.A N GLY 225.A O no hydrogen 2.935 N/A SER 230.A N ALA 226.A O no hydrogen 3.032 N/A SER 230.A OG HIS 166.A ND1 no hydrogen 2.767 N/A SER 230.A OG ALA 226.A O no hydrogen 3.116 N/A SER 231.A N LEU 228.A O no hydrogen 3.060 N/A GLU 234.A N SER 231.A OG no hydrogen 3.379 N/A LEU 235.A N SER 231.A O no hydrogen 2.942 N/A LYS 236.A N ILE 232.A O no hydrogen 3.352 N/A HIS 237.A N SER 233.A O no hydrogen 2.942 N/A ALA 238.A N GLU 234.A O no hydrogen 2.748 N/A SER 240.A N HIS 237.A O no hydrogen 3.115 N/A SER 240.A OG HIS 237.A O no hydrogen 2.676 N/A SER 240.A OG HIS 242.A ND1 no hydrogen 3.184 N/A HIS 242.A N SER 240.A OG no hydrogen 3.382 N/A LYS 246.A N TYR 267.A O no hydrogen 2.879 N/A PHE 248.A N VAL 269.A O no hydrogen 2.834 N/A ASP 249.A N THR 253.A OG1 no hydrogen 3.300 N/A LYS 251.A NZ ASP 249.A OD1 no hydrogen 3.216 N/A ILE 252.A N ASP 249.A O no hydrogen 2.764 N/A THR 253.A N ASP 249.A O no hydrogen 2.709 N/A THR 253.A OG1 ASP 249.A O no hydrogen 3.231 N/A CYS 254.A N PRO 250.A O no hydrogen 2.897 N/A CYS 254.A SG LYS 251.A O no hydrogen 3.682 N/A LYS 255.A N ILE 252.A O no hydrogen 3.091 N/A GLN 256.A N THR 253.A O no hydrogen 3.064 N/A LEU 259.A N GLN 264.A OE1 no hydrogen 3.433 N/A THR 262.A OG1 PHE 263.A O no hydrogen 2.988 N/A GLN 264.A N GLU 234.A OE1 no hydrogen 2.813 N/A GLN 264.A NE2 LEU 259.A O no hydrogen 2.861 N/A TYR 267.A N LYS 244.A O no hydrogen 2.901 N/A TYR 267.A OH GLU 234.A OE1 no hydrogen 2.532 N/A VAL 269.A N LYS 246.A O no hydrogen 2.667 N/A SER 270.A N LEU 214.A O no hydrogen 2.814 N/A SER 272.A OG GLU 274.A OE1 no hydrogen 3.348 N/A GLU 274.A N GLU 274.A OE1 no hydrogen 2.647 N/A ASP 275.A N SER 272.A OG no hydrogen 2.952 N/A ALA 276.A N SER 272.A O no hydrogen 2.992 N/A LYS 277.A N PHE 273.A O no hydrogen 3.031 N/A GLU 278.A N GLU 274.A O no hydrogen 2.998 N/A LYS 279.A N ASP 275.A O no hydrogen 2.881 N/A LYS 279.A NZ ASP 275.A OD2 no hydrogen 3.274 N/A MET 280.A N ALA 276.A O no hydrogen 2.931 N/A ARG 281.A N LYS 277.A O no hydrogen 3.030 N/A ARG 281.A NE GLU 186.A OE1 no hydrogen 2.907 N/A ARG 281.A NH2 GLU 186.A OE2 no hydrogen 2.699 N/A GLU 282.A N GLU 278.A O no hydrogen 3.164 N/A PHE 283.A N LYS 279.A O no hydrogen 3.000 N/A THR 284.A N MET 280.A O no hydrogen 2.758 N/A THR 284.A OG1 MET 280.A O no hydrogen 3.199 N/A THR 284.A OG1 ARG 281.A O no hydrogen 3.111 N/A THR 286.A N PHE 283.A O no hydrogen 3.079 N/A THR 286.A OG1 PHE 283.A O no hydrogen 2.739 N/A ILE 287.A N THR 284.A O no hydrogen 3.224 N/A