Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8cpi_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 5.A N SER 8.A OG no hydrogen 3.202 N/A SER 8.A N ASN 5.A OD1 no hydrogen 3.044 N/A SER 8.A OG GLN 3.A O no hydrogen 3.126 N/A SER 8.A OG ASN 5.A O no hydrogen 3.279 N/A ALA 9.A N ASN 5.A O no hydrogen 3.135 N/A ASP 10.A N PRO 6.A O no hydrogen 3.296 N/A ASP 10.A N GLU 7.A O no hydrogen 3.198 N/A LEU 11.A N GLU 7.A O no hydrogen 3.092 N/A ARG 12.A N SER 8.A O no hydrogen 2.885 N/A ARG 12.A NH1 GLN 220.A OE1 no hydrogen 3.409 N/A ARG 12.A NH2 GLN 220.A OE1 no hydrogen 2.850 N/A ALA 13.A N ALA 9.A O no hydrogen 2.934 N/A LEU 14.A N ASP 10.A O no hydrogen 2.665 N/A ALA 15.A N LEU 11.A O no hydrogen 2.995 N/A LYS 16.A N ARG 12.A O no hydrogen 2.990 N/A LYS 16.A NZ ASP 20.A OD2 no hydrogen 3.281 N/A HIS 17.A N ALA 13.A O no hydrogen 3.005 N/A HIS 17.A NE2 SER 102.A O no hydrogen 2.720 N/A LEU 18.A N LEU 14.A O no hydrogen 3.035 N/A TYR 19.A N ALA 15.A O no hydrogen 2.992 N/A ASP 20.A N LYS 16.A O no hydrogen 2.994 N/A SER 21.A N HIS 17.A O no hydrogen 2.907 N/A SER 21.A OG HIS 17.A O no hydrogen 2.829 N/A TYR 22.A N LEU 18.A O no hydrogen 2.869 N/A TYR 22.A OH ASP 181.A OD1 no hydrogen 2.618 N/A ILE 23.A N TYR 19.A O no hydrogen 2.846 N/A LYS 24.A N ASP 20.A O no hydrogen 3.113 N/A SER 25.A N TYR 22.A O no hydrogen 3.078 N/A SER 25.A OG SER 21.A O no hydrogen 2.629 N/A PHE 26.A N TYR 22.A O no hydrogen 3.037 N/A LYS 30.A N ASP 181.A OD1 no hydrogen 2.897 N/A LYS 30.A NZ LEU 179.A O no hydrogen 2.744 N/A ALA 31.A N ASP 181.A OD2 no hydrogen 3.031 N/A LYS 32.A N THR 29.A OG1 no hydrogen 3.013 N/A ALA 33.A N THR 29.A O no hydrogen 3.047 N/A ARG 34.A N LYS 30.A O no hydrogen 2.870 N/A ARG 34.A NH2 SER 132.A O no hydrogen 2.813 N/A ARG 34.A NH2 MET 134.A O no hydrogen 2.605 N/A ALA 35.A N ALA 31.A O no hydrogen 3.254 N/A ILE 36.A N LYS 32.A O no hydrogen 3.118 N/A LEU 37.A N ALA 33.A O no hydrogen 2.954 N/A THR 38.A N ARG 34.A O no hydrogen 3.035 N/A THR 38.A OG1 ARG 34.A O no hydrogen 2.890 N/A THR 38.A OG1 ALA 35.A O no hydrogen 3.103 N/A GLY 39.A N ILE 36.A O no hydrogen 3.097 N/A THR 41.A N ALA 35.A O no hydrogen 3.255 N/A ASP 43.A N THR 41.A OG1 no hydrogen 3.419 N/A SER 45.A OG PRO 46.A O no hydrogen 2.971 N/A PHE 47.A N GLN 145.A O no hydrogen 2.901 N/A ILE 49.A N PHE 147.A O no hydrogen 2.783 N/A TYR 50.A N SER 54.A OG no hydrogen 2.928 N/A ASP 51.A N SER 54.A OG no hydrogen 2.980 N/A SER 54.A N ASP 51.A OD1 no hydrogen 3.054 N/A SER 54.A OG ASP 51.A O no hydrogen 2.955 N/A SER 54.A OG ASP 51.A OD1 no hydrogen 2.642 N/A LEU 55.A N ASP 51.A O no hydrogen 2.974 N/A MET 56.A N MET 52.A O no hydrogen 3.177 N/A MET 56.A N ASN 53.A O no hydrogen 3.168 N/A MET 57.A N ASN 53.A O no hydrogen 2.991 N/A GLY 58.A N SER 54.A O no hydrogen 2.703 N/A GLU 59.A N LEU 55.A O no hydrogen 2.863 N/A ASP 60.A N MET 56.A O no hydrogen 3.329 N/A LYS 61.A N GLY 58.A O no hydrogen 3.004 N/A ILE 62.A N GLY 58.A O no hydrogen 2.709 N/A PHE 64.A N ILE 62.A O no hydrogen 3.180 N/A GLN 73.A N PRO 69.A O no hydrogen 3.391 N/A GLN 73.A NE2 GLN 73.A O no hydrogen 3.370 N/A SER 74.A OG LEU 70.A O no hydrogen 2.981 N/A LYS 75.A N GLU 72.A O no hydrogen 2.667 N/A ARG 80.A N GLU 76.A O no hydrogen 3.080 N/A ARG 80.A NE GLU 59.A OE1 no hydrogen 3.242 N/A ARG 80.A NE GLU 59.A OE2 no hydrogen 3.358 N/A ARG 80.A NH1 GLU 59.A OE1 no hydrogen 2.449 N/A ARG 80.A NH2 LYS 75.A O no hydrogen 3.373 N/A ILE 81.A N VAL 77.A O no hydrogen 2.873 N/A PHE 82.A N ALA 78.A O no hydrogen 3.044 N/A GLN 83.A N ILE 79.A O no hydrogen 2.875 N/A GLN 83.A NE2 GLU 72.A OE1 no hydrogen 3.561 N/A GLY 84.A N ARG 80.A O no hydrogen 3.035 N/A CYS 85.A N ILE 81.A O no hydrogen 2.942 N/A CYS 85.A SG ILE 81.A O no hydrogen 3.359 N/A GLN 86.A N PHE 82.A O no hydrogen 2.836 N/A GLN 86.A NE2 SER 264.A O no hydrogen 3.201 N/A PHE 87.A N GLN 83.A O no hydrogen 2.889 N/A ARG 88.A N GLY 84.A O no hydrogen 2.968 N/A ARG 88.A NH1 GLU 91.A OE1 no hydrogen 3.187 N/A ARG 88.A NH1 GLU 95.A OE2 no hydrogen 3.570 N/A SER 89.A N CYS 85.A O no hydrogen 2.941 N/A SER 89.A OG CYS 85.A O no hydrogen 3.265 N/A VAL 90.A N GLN 86.A O no hydrogen 3.129 N/A GLU 91.A N PHE 87.A O no hydrogen 3.126 N/A ALA 92.A N ARG 88.A O no hydrogen 2.955 N/A VAL 93.A N SER 89.A O no hydrogen 3.036 N/A GLN 94.A N VAL 90.A O no hydrogen 3.034 N/A GLU 95.A N GLU 91.A O no hydrogen 2.827 N/A ILE 96.A N ALA 92.A O no hydrogen 2.833 N/A THR 97.A N VAL 93.A O no hydrogen 2.836 N/A THR 97.A OG1 VAL 93.A O no hydrogen 3.086 N/A GLU 98.A N GLN 94.A O no hydrogen 3.078 N/A TYR 99.A N GLU 95.A O no hydrogen 3.123 N/A TYR 99.A OH ALA 185.A O no hydrogen 2.619 N/A ALA 100.A N ILE 96.A O no hydrogen 2.912 N/A LYS 101.A N THR 97.A O no hydrogen 3.089 N/A LYS 101.A N GLU 98.A O no hydrogen 3.143 N/A SER 102.A N TYR 99.A O no hydrogen 2.859 N/A SER 102.A OG TYR 99.A O no hydrogen 2.765 N/A ILE 103.A N ALA 100.A O no hydrogen 3.094 N/A PHE 106.A N ILE 103.A O no hydrogen 2.886 N/A ASN 108.A N GLY 105.A O no hydrogen 2.969 N/A ASN 108.A ND2 GLY 105.A O no hydrogen 3.538 N/A LEU 109.A N PHE 106.A O no hydrogen 3.096 N/A ASN 112.A N ASP 110.A OD1 no hydrogen 3.106 N/A GLN 114.A N ASP 110.A O no hydrogen 3.003 N/A GLN 114.A NE2 LEU 109.A O no hydrogen 2.838 N/A VAL 115.A N LEU 111.A O no hydrogen 3.070 N/A THR 116.A N ASN 112.A O no hydrogen 2.981 N/A THR 116.A OG1 ASN 112.A O no hydrogen 3.136 N/A LEU 117.A N ASP 113.A O no hydrogen 3.044 N/A LEU 118.A N GLN 114.A O no hydrogen 3.404 N/A LYS 119.A N VAL 115.A O no hydrogen 2.958 N/A TYR 120.A N THR 116.A O no hydrogen 3.080 N/A TYR 120.A OH ASP 275.A O no hydrogen 3.071 N/A GLY 121.A N LEU 118.A O no hydrogen 3.013 N/A VAL 122.A N LEU 118.A O no hydrogen 2.748 N/A ILE 125.A N GLY 121.A O no hydrogen 3.170 N/A ILE 126.A N VAL 122.A O no hydrogen 2.840 N/A TYR 127.A N HIS 123.A O no hydrogen 3.075 N/A THR 128.A N GLU 124.A O no hydrogen 3.126 N/A THR 128.A OG1 GLU 124.A O no hydrogen 2.873 N/A MET 129.A N ILE 125.A O no hydrogen 2.972 N/A LEU 130.A N ILE 126.A O no hydrogen 2.739 N/A ALA 131.A N TYR 127.A O no hydrogen 3.186 N/A SER 132.A N MET 129.A O no hydrogen 2.933 N/A LEU 133.A N LEU 130.A O no hydrogen 2.888 N/A MET 134.A N ALA 131.A O no hydrogen 3.143 N/A ASN 135.A N GLY 138.A O no hydrogen 3.042 N/A ASP 137.A N ASN 135.A OD1 no hydrogen 2.798 N/A GLY 138.A N ASN 135.A OD1 no hydrogen 3.086 N/A VAL 139.A N MET 148.A O no hydrogen 2.958 N/A LEU 140.A N LEU 133.A O no hydrogen 2.903 N/A ILE 141.A N GLY 146.A O no hydrogen 2.869 N/A GLY 144.A N ILE 141.A O no hydrogen 3.059 N/A GLN 145.A N SER 142.A O no hydrogen 3.136 N/A GLN 145.A NE2 LYS 63.A O no hydrogen 3.225 N/A GLN 145.A NE2 SER 142.A O no hydrogen 3.395 N/A GLY 146.A N ILE 141.A O no hydrogen 3.042 N/A PHE 147.A N PHE 47.A O no hydrogen 2.868 N/A MET 148.A N VAL 139.A O no hydrogen 2.926 N/A THR 149.A N ILE 49.A O no hydrogen 2.985 N/A ARG 150.A N ASP 137.A O no hydrogen 2.818 N/A ARG 150.A NE GLU 165.A OE1 no hydrogen 3.301 N/A ARG 150.A NE GLU 165.A OE2 no hydrogen 2.961 N/A ARG 150.A NH2 GLU 165.A OE2 no hydrogen 2.648 N/A PHE 152.A N THR 149.A OG1 no hydrogen 3.053 N/A LEU 153.A N THR 149.A O no hydrogen 3.239 N/A LYS 154.A N ARG 150.A O no hydrogen 3.005 N/A LYS 154.A NZ GLU 151.A OE2 no hydrogen 3.022 N/A SER 155.A N GLU 151.A O no hydrogen 3.014 N/A SER 155.A N PHE 152.A O no hydrogen 3.034 N/A SER 155.A OG PHE 152.A O no hydrogen 2.523 N/A LEU 156.A N LEU 153.A O no hydrogen 3.256 N/A ARG 157.A NE GLU 76.A OE1 no hydrogen 2.819 N/A ARG 157.A NE GLU 76.A OE2 no hydrogen 2.768 N/A ARG 157.A NH1 GLU 76.A OE2 no hydrogen 2.756 N/A ARG 157.A NH1 GLU 260.A OE1 no hydrogen 2.796 N/A ARG 157.A NH2 LYS 158.A O no hydrogen 2.723 N/A ARG 157.A NH2 GLU 260.A OE2 no hydrogen 3.215 N/A PHE 160.A N ARG 157.A O no hydrogen 2.815 N/A LYS 167.A NZ PHE 163.A O no hydrogen 2.791 N/A LYS 167.A NZ HIS 249.A ND1 no hydrogen 3.080 N/A PHE 168.A N MET 164.A O no hydrogen 3.046 N/A GLU 169.A N GLU 165.A O no hydrogen 2.971 N/A PHE 170.A N PRO 166.A O no hydrogen 2.960 N/A ALA 171.A N LYS 167.A O no hydrogen 2.872 N/A VAL 172.A N PHE 168.A O no hydrogen 2.974 N/A PHE 174.A N PHE 170.A O no hydrogen 2.821 N/A ASN 175.A N ALA 171.A O no hydrogen 2.661 N/A ASN 175.A ND2 ALA 131.A O no hydrogen 2.876 N/A ALA 176.A N LYS 173.A O no hydrogen 3.306 N/A LEU 177.A N PHE 174.A O no hydrogen 2.978 N/A GLU 178.A N ASN 175.A O no hydrogen 3.080 N/A ASP 180.A N ASP 183.A OD2 no hydrogen 2.949 N/A SER 182.A OG ASP 180.A OD1 no hydrogen 2.583 N/A ASP 183.A N ASP 180.A OD1 no hydrogen 2.989 N/A LEU 184.A N ASP 180.A O no hydrogen 2.956 N/A ALA 185.A N ASP 181.A O no hydrogen 2.870 N/A ILE 186.A N ASP 183.A O no hydrogen 3.136 N/A PHE 187.A N ASP 183.A O no hydrogen 3.031 N/A ILE 188.A N LEU 184.A O no hydrogen 2.779 N/A ALA 189.A N ALA 185.A O no hydrogen 3.231 N/A VAL 190.A N ILE 186.A O no hydrogen 2.948 N/A ILE 191.A N PHE 187.A O no hydrogen 3.258 N/A ILE 192.A N ILE 188.A O no hydrogen 2.948 N/A LEU 193.A N ALA 189.A O no hydrogen 3.098 N/A SER 194.A OG ILE 191.A O no hydrogen 2.438 N/A ARG 197.A NH1 GLU 124.A OE1 no hydrogen 3.307 N/A ARG 197.A NH1 GLU 124.A OE2 no hydrogen 2.817 N/A ARG 197.A NH2 GLU 124.A OE1 no hydrogen 2.590 N/A ARG 197.A NH2 ILE 191.A O no hydrogen 3.247 N/A LEU 201.A N ASP 113.A OD1 no hydrogen 2.805 N/A ASN 202.A N ASP 113.A OD2 no hydrogen 3.066 N/A ASN 202.A ND2 ASP 113.A OD2 no hydrogen 3.297 N/A GLU 207.A N VAL 203.A O no hydrogen 2.976 N/A ASP 208.A N LYS 204.A O no hydrogen 2.811 N/A ILE 209.A N PRO 205.A O no hydrogen 3.080 N/A GLN 210.A N ILE 206.A O no hydrogen 2.965 N/A GLN 210.A NE2 VAL 190.A O no hydrogen 3.141 N/A ASP 211.A N GLU 207.A O no hydrogen 2.960 N/A ASN 212.A N ASP 208.A O no hydrogen 3.514 N/A LEU 213.A N ILE 209.A O no hydrogen 3.107 N/A LEU 214.A N GLN 210.A O no hydrogen 2.683 N/A GLN 215.A N ASP 211.A O no hydrogen 2.991 N/A ALA 216.A N ASN 212.A O no hydrogen 2.972 N/A LEU 217.A N LEU 213.A O no hydrogen 2.822 N/A GLU 218.A N LEU 214.A O no hydrogen 2.940 N/A LEU 219.A N GLN 215.A O no hydrogen 2.969 N/A GLN 220.A N ALA 216.A O no hydrogen 2.948 N/A GLN 220.A NE2 ASP 183.A OD1 no hydrogen 2.926 N/A LEU 221.A N LEU 217.A O no hydrogen 2.894 N/A LYS 222.A N GLU 218.A O no hydrogen 3.119 N/A LEU 223.A N LEU 219.A O no hydrogen 2.989 N/A ASN 224.A N GLN 220.A O no hydrogen 2.820 N/A ASN 224.A ND2 ASP 180.A OD2 no hydrogen 2.778 N/A ASN 224.A ND2 ASP 183.A OD1 no hydrogen 3.049 N/A ASN 224.A ND2 ASP 183.A OD2 no hydrogen 3.404 N/A HIS 225.A N LEU 221.A O no hydrogen 2.738 N/A HIS 225.A ND1 GLU 227.A OE2 no hydrogen 2.711 N/A HIS 225.A NE2 ASP 183.A OD2 no hydrogen 2.587 N/A GLU 227.A N GLU 227.A OE1 no hydrogen 2.732 N/A SER 228.A N HIS 225.A O no hydrogen 3.388 N/A GLN 230.A N SER 228.A OG no hydrogen 2.985 N/A LYS 234.A N GLN 230.A O no hydrogen 2.935 N/A LEU 235.A N LEU 231.A O no hydrogen 2.984 N/A LEU 235.A N PHE 232.A O no hydrogen 3.133 N/A LEU 236.A N PHE 232.A O no hydrogen 3.094 N/A GLN 237.A N ALA 233.A O no hydrogen 3.171 N/A LYS 238.A N LYS 234.A O no hydrogen 3.080 N/A MET 239.A N LEU 235.A O no hydrogen 3.082 N/A THR 240.A N GLN 237.A O no hydrogen 3.005 N/A ASP 241.A N GLN 237.A O no hydrogen 2.899 N/A LEU 242.A N LYS 238.A O no hydrogen 2.917 N/A ARG 243.A NH1 ASP 196.A OD2 no hydrogen 3.187 N/A ARG 243.A NH2 ASP 196.A OD1 no hydrogen 2.997 N/A ILE 245.A N ASP 241.A O no hydrogen 3.131 N/A VAL 246.A N LEU 242.A O no hydrogen 2.989 N/A THR 247.A N ARG 243.A O no hydrogen 2.914 N/A THR 247.A OG1 ARG 243.A O no hydrogen 3.293 N/A GLU 248.A N GLN 244.A O no hydrogen 2.881 N/A HIS 249.A N ILE 245.A O no hydrogen 2.967 N/A VAL 250.A N VAL 246.A O no hydrogen 3.197 N/A GLN 251.A N THR 247.A O no hydrogen 3.259 N/A LEU 252.A N GLU 248.A O no hydrogen 3.132 N/A LEU 253.A N HIS 249.A O no hydrogen 2.896 N/A GLN 254.A N VAL 250.A O no hydrogen 2.907 N/A VAL 255.A N GLN 251.A O no hydrogen 3.194 N/A ILE 256.A N LEU 252.A O no hydrogen 2.992 N/A LYS 257.A N LEU 253.A O no hydrogen 2.787 N/A LYS 258.A N GLN 254.A O no hydrogen 2.765 N/A THR 259.A N ILE 256.A O no hydrogen 3.149 N/A THR 259.A OG1 VAL 255.A O no hydrogen 2.547 N/A GLU 260.A N ILE 256.A O no hydrogen 2.668 N/A MET 263.A N GLU 260.A O no hydrogen 3.038 N/A HIS 266.A N GLN 86.A OE1 no hydrogen 2.615 N/A LEU 268.A N HIS 266.A ND1 no hydrogen 3.110 N/A GLN 270.A N HIS 266.A O no hydrogen 2.904 N/A GLU 271.A N PRO 267.A O no hydrogen 2.831 N/A ILE 272.A N LEU 268.A O no hydrogen 3.185 N/A TYR 273.A N LEU 269.A O no hydrogen 2.947 N/A TYR 273.A OH HIS 123.A NE2 no hydrogen 2.866 N/A LYS 274.A N GLN 270.A O no hydrogen 3.049 N/A LEU 276.A N TYR 273.A O no hydrogen 3.081 N/A