Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8cr0_X.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLY 2.A N ASN 7.A O no hydrogen 2.978 N/A GLY 4.A N ASN 7.A OD1 no hydrogen 2.890 N/A ASN 7.A N GLY 4.A O no hydrogen 3.300 N/A HIS 11.A N GLY 8.A O no hydrogen 2.795 N/A HIS 11.A NE2 LYS 5.A O no hydrogen 2.956 N/A TRP 12.A NE1 GLY 2.A O no hydrogen 3.118 N/A TRP 12.A NE1 ASN 7.A O no hydrogen 3.050 N/A LYS 14.A N HIS 11.A O no hydrogen 3.153 N/A LYS 14.A NZ HIS 11.A ND1 no hydrogen 2.808 N/A ASP 15.A N TRP 12.A O no hydrogen 3.168 N/A PHE 16.A N TRP 12.A O no hydrogen 2.886 N/A ALA 19.A N PHE 16.A O no hydrogen 2.862 N/A LYS 20.A N PRO 17.A O no hydrogen 3.092 N/A GLY 21.A N ILE 18.A O.A no hydrogen 2.807 N/A GLY 21.A N ILE 18.A O.B no hydrogen 2.810 N/A ARG 23.A N GLU 200.A OE2 no hydrogen 2.996 N/A ARG 23.A NE GLY 191.A O no hydrogen 2.949 N/A ARG 23.A NH1 PRO 133.A O no hydrogen 3.119 N/A ARG 23.A NH2 PRO 133.A O no hydrogen 3.164 N/A ARG 23.A NH2 GLY 191.A O no hydrogen 2.873 N/A ARG 23.A NH2 VAL 202.A O no hydrogen 3.041 N/A GLN 24.A NE2 LEU 198.A O no hydrogen 3.107 N/A GLN 24.A NE2 GLU 200.A OE2 no hydrogen 3.039 N/A SER 25.A N SER 192.A OG no hydrogen 2.899 N/A SER 25.A OG TYR 189.A OH no hydrogen 2.773 N/A SER 25.A OG SER 192.A O no hydrogen 3.550 N/A ILE 29.A N THR 104.A O no hydrogen 2.747 N/A THR 31.A N ASP 106.A OD1 no hydrogen 2.840 N/A THR 31.A OG1 ASP 106.A OD1 no hydrogen 3.331 N/A THR 31.A OG1 ASP 106.A OD2 no hydrogen 2.667 N/A HIS 32.A N ASP 30.A OD1.A no hydrogen 3.035 N/A THR 33.A N ASP 30.A O.A no hydrogen 3.173 N/A THR 33.A N ASP 30.A O.B no hydrogen 3.136 N/A THR 33.A N ASP 30.A OD1.A no hydrogen 3.234 N/A THR 33.A N ASP 30.A OD2.B no hydrogen 3.207 N/A THR 33.A OG1 ASP 30.A OD2.A no hydrogen 3.030 N/A THR 33.A OG1 ASP 30.A OD2.B no hydrogen 2.931 N/A ALA 34.A N ASP 30.A O.A no hydrogen 2.998 N/A ALA 34.A N ASP 30.A O.B no hydrogen 3.029 N/A LYS 35.A N ILE 251.A O no hydrogen 3.016 N/A ASP 37.A N ALA 253.A O no hydrogen 2.948 N/A SER 39.A N ASP 37.A OD1 no hydrogen 3.139 N/A SER 39.A OG ASP 37.A OD1 no hydrogen 2.675 N/A LEU 40.A N ASP 37.A O no hydrogen 3.001 N/A SER 44.A N LYS 76.A O no hydrogen 2.858 N/A SER 46.A N.A VAL 74.A O no hydrogen 2.888 N/A SER 46.A N.B VAL 74.A O no hydrogen 2.895 N/A SER 46.A OG.B ASP 48.A OD1.A no hydrogen 3.272 N/A TYR 47.A OH HIS 118.A NE2 no hydrogen 2.729 N/A GLN 49.A NE2 ASP 48.A OD1.B no hydrogen 2.975 N/A ALA 50.A N TYR 47.A O no hydrogen 3.030 N/A THR 51.A OG1 GLN 49.A O no hydrogen 3.567 N/A SER 52.A OG PHE 171.A O no hydrogen 2.570 N/A LEU 53.A N GLU 65.A O no hydrogen 2.765 N/A ARG 54.A NE GLU 65.A OE1 no hydrogen 2.775 N/A ARG 54.A NH2 GLU 65.A OE1 no hydrogen 3.248 N/A ARG 54.A NH2 GLU 65.A OE2 no hydrogen 2.801 N/A ILE 55.A N ALA 169.A O no hydrogen 2.940 N/A LEU 56.A N ASN 63.A O no hydrogen 2.909 N/A ASN 57.A N LYS 167.A O no hydrogen 2.927 N/A ASN 57.A ND2 ILE 162.A O no hydrogen 3.136 N/A ASN 57.A ND2 ASN 225.A O no hydrogen 3.146 N/A ASN 58.A N ALA 61.A O no hydrogen 3.095 N/A GLY 59.A N ASN 57.A OD1 no hydrogen 2.875 N/A HIS 60.A N ASN 58.A OD1 no hydrogen 2.943 N/A ALA 61.A N ASN 58.A OD1 no hydrogen 2.988 N/A ASN 63.A N LEU 56.A O no hydrogen 2.832 N/A VAL 64.A N PHE 89.A O no hydrogen 2.877 N/A GLU 65.A N ARG 54.A O no hydrogen 2.859 N/A PHE 66.A N ILE 87.A O no hydrogen 2.943 N/A ASP 67.A N THR 51.A O no hydrogen 2.895 N/A SER 69.A N ASP 67.A OD1 no hydrogen 2.920 N/A SER 69.A OG ASP 67.A OD1 no hydrogen 2.719 N/A LYS 72.A N GLN 70.A O no hydrogen 2.922 N/A LYS 72.A NZ THR 51.A OG1 no hydrogen 2.915 N/A LYS 72.A NZ ASP 67.A OD2 no hydrogen 2.769 N/A VAL 74.A N SER 46.A O.A no hydrogen 2.950 N/A VAL 74.A N SER 46.A O.B no hydrogen 2.895 N/A LEU 75.A N TYR 84.A O no hydrogen 2.829 N/A LYS 76.A N SER 44.A O no hydrogen 2.943 N/A GLY 78.A N PRO 42.A O no hydrogen 3.139 N/A LEU 80.A N GLY 77.A O no hydrogen 2.930 N/A TYR 84.A N LEU 75.A O no hydrogen 2.993 N/A TYR 84.A OH ASP 134.A O no hydrogen 3.025 N/A ARG 85.A N TRP 119.A O no hydrogen 2.831 N/A ARG 85.A NE ASP 71.A OD1 no hydrogen 2.637 N/A ARG 85.A NH1 ASP 68.A O no hydrogen 2.923 N/A ARG 85.A NH2 ASP 71.A OD1 no hydrogen 3.253 N/A LEU 86.A N ALA 73.A O no hydrogen 2.871 N/A ILE 87.A N VAL 117.A O no hydrogen 2.922 N/A PHE 89.A N VAL 64.A O no hydrogen 2.975 N/A HIS 90.A N HIS 115.A O no hydrogen 3.106 N/A HIS 90.A ND1 GLN 88.A OE1 no hydrogen 2.754 N/A HIS 92.A N GLU 113.A O no hydrogen 2.910 N/A HIS 92.A ND1 ASN 239.A O no hydrogen 2.751 N/A HIS 92.A NE2 HIS 115.A ND1 no hydrogen 3.024 N/A TRP 93.A N ASN 239.A OD1 no hydrogen 2.808 N/A TRP 93.A NE1 MET 236.A O no hydrogen 2.820 N/A SER 95.A N ASP 238.A OD1 no hydrogen 3.056 N/A SER 95.A OG ASP 238.A OD2 no hydrogen 2.682 N/A GLN 99.A N LEU 96.A O no hydrogen 3.294 N/A GLN 99.A NE2 ASP 238.A OD1 no hydrogen 2.882 N/A GLN 99.A NE2 ASP 238.A OD2 no hydrogen 3.454 N/A SER 101.A N TYR 110.A O no hydrogen 2.991 N/A SER 101.A OG HIS 103.A O no hydrogen 2.771 N/A GLU 102.A N GLU 113.A OE1 no hydrogen 2.838 N/A HIS 103.A N GLU 113.A OE1 no hydrogen 2.823 N/A HIS 103.A ND1 GLU 113.A OE2 no hydrogen 2.756 N/A HIS 103.A NE2 TYR 189.A OH no hydrogen 2.651 N/A THR 104.A N VAL 27.A O no hydrogen 3.480 N/A THR 104.A OG1 ASP 28.A OD1 no hydrogen 2.677 N/A VAL 105.A N LYS 108.A O no hydrogen 3.039 N/A ASP 106.A N ILE 29.A O no hydrogen 2.848 N/A LYS 107.A N ASP 28.A OD1 no hydrogen 2.801 N/A LYS 108.A N VAL 105.A O no hydrogen 2.831 N/A TYR 110.A N SER 101.A OG no hydrogen 2.930 N/A ALA 111.A N LEU 143.A O no hydrogen 3.086 N/A ALA 112.A N LEU 143.A O no hydrogen 3.396 N/A GLU 113.A N HIS 92.A O no hydrogen 2.879 N/A LEU 114.A N ILE 141.A O no hydrogen 2.812 N/A HIS 115.A N HIS 90.A O no hydrogen 2.823 N/A HIS 115.A NE2 GLU 113.A OE2 no hydrogen 2.682 N/A LEU 116.A N LEU 139.A O no hydrogen 2.897 N/A VAL 117.A N GLN 88.A O no hydrogen 2.850 N/A HIS 118.A N ALA 137.A O no hydrogen 2.944 N/A HIS 118.A ND1 ALA 137.A O no hydrogen 3.012 N/A HIS 118.A NE2 TYR 47.A OH no hydrogen 2.729 N/A TRP 119.A N ARG 85.A O no hydrogen 2.913 N/A TRP 119.A NE1 ASP 68.A OD2 no hydrogen 2.819 N/A ASN 120.A N GLY 135.A O no hydrogen 2.795 N/A ASN 120.A ND2 ASP 134.A O no hydrogen 3.163 N/A THR 121.A N THR 83.A O no hydrogen 2.968 N/A THR 121.A OG1 THR 83.A O no hydrogen 3.266 N/A LYS 122.A N ASN 120.A OD1 no hydrogen 3.116 N/A LYS 122.A NZ ASP 134.A OD2 no hydrogen 3.161 N/A TYR 123.A N ASN 120.A O no hydrogen 3.034 N/A TYR 123.A OH ASP 134.A OD1 no hydrogen 2.601 N/A GLY 124.A N THR 121.A O no hydrogen 3.137 N/A ASP 125.A N TYR 123.A O no hydrogen 2.895 N/A LYS 128.A N ASP 125.A OD1 no hydrogen 2.871 N/A ALA 129.A N ASP 125.A O no hydrogen 3.007 N/A VAL 130.A N PHE 126.A O no hydrogen 3.029 N/A GLN 131.A N LYS 128.A O no hydrogen 3.068 N/A GLN 131.A NE2 GLY 127.A O no hydrogen 3.006 N/A GLN 132.A N ALA 129.A O no hydrogen 2.997 N/A GLN 132.A NE2 LYS 128.A O no hydrogen 3.228 N/A GLY 135.A N GLN 132.A O no hydrogen 3.126 N/A LEU 136.A N CYS 201.A O no hydrogen 2.846 N/A ALA 137.A N HIS 118.A O no hydrogen 2.896 N/A VAL 138.A N THR 203.A O no hydrogen 3.089 N/A LEU 139.A N LEU 116.A O no hydrogen 2.965 N/A GLY 140.A N ILE 205.A O no hydrogen 2.831 N/A ILE 141.A N LEU 114.A O no hydrogen 2.895 N/A LEU 143.A N ALA 112.A O no hydrogen 2.925 N/A LYS 144.A N ILE 211.A O no hydrogen 2.929 N/A GLY 146.A N VAL 213.A O no hydrogen 2.761 N/A SER 147.A OG.B SER 212.A OG.B no hydrogen 3.007 N/A LYS 149.A N GLN 217.A OE1 no hydrogen 2.980 N/A LYS 149.A NZ LEU 180.A O no hydrogen 3.264 N/A LEU 152.A N LYS 149.A O no hydrogen 3.016 N/A GLN 153.A N PRO 150.A O no hydrogen 3.093 N/A GLN 153.A NE2 ASP 157.A OD1 no hydrogen 3.090 N/A GLN 153.A NE2 ASP 157.A OD2 no hydrogen 3.180 N/A VAL 155.A N LEU 152.A O no hydrogen 2.992 N/A VAL 156.A N LEU 152.A O no hydrogen 3.147 N/A ASP 157.A N GLN 153.A O no hydrogen 2.841 N/A VAL 158.A N VAL 155.A O no hydrogen 3.209 N/A LEU 159.A N VAL 156.A O no hydrogen 3.280 N/A SER 161.A N VAL 158.A O no hydrogen 2.953 N/A SER 161.A OG VAL 158.A O no hydrogen 2.645 N/A ILE 162.A N LEU 159.A O no hydrogen 3.017 N/A LYS 163.A NZ GLU 233.A OE2 no hydrogen 3.409 N/A LYS 165.A N ASN 227.A O no hydrogen 2.937 N/A GLY 166.A N ASN 57.A O no hydrogen 2.800 N/A LYS 167.A N THR 164.A O no hydrogen 3.110 N/A ALA 169.A N ILE 55.A O no hydrogen 2.926 N/A PHE 171.A N LEU 53.A O no hydrogen 3.027 N/A THR 172.A N ASP 170.A OD1 no hydrogen 2.959 N/A THR 172.A OG1 ASP 170.A OD1 no hydrogen 2.778 N/A PHE 174.A N SER 52.A OG no hydrogen 2.902 N/A ARG 177.A N ASP 175.A OD1 no hydrogen 2.978 N/A ARG 177.A NE ASP 175.A OD1 no hydrogen 3.011 N/A ARG 177.A NE ASP 175.A OD2 no hydrogen 3.224 N/A ARG 177.A NH1 ASP 48.A OD2.B no hydrogen 3.059 N/A ARG 177.A NH2 ASP 175.A OD2 no hydrogen 2.959 N/A GLY 178.A N ASP 175.A O no hydrogen 3.161 N/A LEU 179.A N PRO 176.A O no hydrogen 3.035 N/A LEU 180.A N ARG 177.A O no hydrogen 3.364 N/A SER 183.A N GLU 209.A OE1 no hydrogen 2.950 N/A ASP 185.A N SER 183.A OG no hydrogen 3.079 N/A TYR 186.A N SER 254.A OG no hydrogen 2.948 N/A TYR 186.A OH LYS 41.A O no hydrogen 2.880 N/A TRP 187.A N VAL 206.A O no hydrogen 2.853 N/A THR 188.A N LYS 252.A O no hydrogen 2.861 N/A THR 188.A OG1 TRP 204.A O no hydrogen 2.779 N/A TYR 189.A N TRP 204.A O no hydrogen 3.248 N/A TYR 189.A OH SER 25.A OG no hydrogen 2.773 N/A TYR 189.A OH HIS 103.A NE2 no hydrogen 2.651 N/A GLY 191.A N VAL 202.A O no hydrogen 2.798 N/A SER 192.A N SER 25.A OG no hydrogen 2.962 N/A SER 192.A OG LEU 193.A O no hydrogen 2.704 N/A LEU 193.A N LEU 199.A O no hydrogen 2.924 N/A THR 194.A OG1 GLU 102.A OE1 no hydrogen 2.589 N/A THR 194.A OG1 GLU 102.A OE2 no hydrogen 3.354 N/A LEU 198.A N THR 195.A O no hydrogen 2.808 N/A CYS 201.A SG LEU 199.A O no hydrogen 3.716 N/A VAL 202.A N GLY 191.A O no hydrogen 3.239 N/A THR 203.A N LEU 136.A O no hydrogen 2.876 N/A TRP 204.A N TYR 189.A O no hydrogen 3.015 N/A TRP 204.A NE1 SER 192.A O no hydrogen 2.996 N/A ILE 205.A N VAL 138.A O no hydrogen 2.964 N/A VAL 206.A N TRP 187.A O no hydrogen 2.791 N/A LEU 207.A N GLY 140.A O no hydrogen 2.898 N/A LYS 208.A N ASP 185.A O no hydrogen 2.941 N/A LYS 208.A NZ ASP 185.A OD2 no hydrogen 2.549 N/A ILE 211.A N PHE 142.A O no hydrogen 2.871 N/A SER 212.A OG.B SER 147.A O.A no hydrogen 3.493 N/A SER 212.A OG.B SER 147.A O.B no hydrogen 3.360 N/A SER 212.A OG.B SER 147.A OG.B no hydrogen 3.007 N/A VAL 213.A N LYS 144.A O no hydrogen 2.888 N/A SER 214.A N GLN 217.A OE1 no hydrogen 3.054 N/A SER 214.A OG GLU 216.A OE1 no hydrogen 3.490 N/A GLU 216.A N GLU 216.A OE1 no hydrogen 2.928 N/A GLN 217.A N SER 214.A OG no hydrogen 3.179 N/A GLN 217.A NE2 LYS 149.A O no hydrogen 2.996 N/A GLN 217.A NE2 GLN 153.A OE1 no hydrogen 2.916 N/A VAL 218.A N SER 214.A O no hydrogen 3.174 N/A LEU 219.A N SER 215.A O no hydrogen 2.912 N/A LYS 220.A N GLU 216.A O no hydrogen 3.192 N/A PHE 221.A N GLN 217.A O no hydrogen 3.468 N/A ARG 222.A N VAL 218.A O no hydrogen 3.298 N/A ARG 222.A N LEU 219.A O no hydrogen 3.126 N/A ARG 222.A NE GLY 94.A O no hydrogen 2.851 N/A ARG 222.A NH1 ASP 97.A OD1 no hydrogen 3.494 N/A ARG 222.A NH2 ASP 97.A OD1 no hydrogen 2.822 N/A LYS 223.A N LYS 220.A O no hydrogen 3.163 N/A LEU 224.A N PHE 221.A O no hydrogen 3.238 N/A ASN 225.A N LYS 163.A O no hydrogen 2.826 N/A ASN 225.A ND2 GLU 233.A OE2 no hydrogen 2.926 N/A PHE 226.A N GLU 234.A O no hydrogen 2.885 N/A ASN 227.A ND2 ASN 225.A OD1 no hydrogen 3.400 N/A ASN 227.A ND2 GLY 228.A O no hydrogen 2.978 N/A GLY 228.A N GLU 231.A OE1 no hydrogen 2.869 N/A GLU 231.A N GLY 228.A O no hydrogen 3.163 N/A GLU 234.A N ASN 227.A OD1 no hydrogen 2.793 N/A MET 236.A N LEU 224.A O no hydrogen 2.800 N/A ASN 239.A N TRP 93.A O no hydrogen 3.324 N/A ASN 239.A ND2 HIS 60.A O no hydrogen 2.906 N/A TRP 240.A NE1 ASP 238.A OD1 no hydrogen 2.998 N/A ARG 241.A N GLU 102.A OE2 no hydrogen 2.814 N/A ARG 241.A NH1 GLN 24.A OE1 no hydrogen 2.784 N/A ARG 241.A NH1 SER 25.A O no hydrogen 2.882 N/A ARG 241.A NH2 ALA 19.A O no hydrogen 3.204 N/A ARG 241.A NH2 GLN 24.A OE1 no hydrogen 3.460 N/A GLN 244.A N PRO 26.A O no hydrogen 2.826 N/A GLN 244.A NE2 PRO 242.A O no hydrogen 2.812 N/A LYS 247.A NZ GLY 21.A O no hydrogen 2.793 N/A ARG 249.A NE LEU 246.A O no hydrogen 2.812 N/A ARG 249.A NH1 GLN 24.A O no hydrogen 3.001 N/A ARG 249.A NH1 PRO 190.A O no hydrogen 2.914 N/A ARG 249.A NH2 GLN 24.A O no hydrogen 2.828 N/A ARG 249.A NH2 PRO 245.A O no hydrogen 2.926 N/A ARG 249.A NH2 LEU 246.A O no hydrogen 3.464 N/A LYS 252.A N THR 188.A O no hydrogen 2.973 N/A ALA 253.A N LYS 35.A O no hydrogen 2.795 N/A SER 254.A N TYR 186.A O no hydrogen 2.866 N/A SER 254.A OG TYR 186.A O no hydrogen 3.339 N/A