Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8cro_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 5.A N SER 2.A OG no hydrogen 3.339 N/A THR 5.A OG1 SER 2.A OG no hydrogen 2.524 N/A SER 8.A N SER 4.A O no hydrogen 2.932 N/A SER 8.A OG THR 5.A O no hydrogen 2.716 N/A LEU 9.A N THR 5.A O no hydrogen 2.882 N/A ILE 10.A N ILE 6.A O no hydrogen 2.937 N/A GLU 11.A N LYS 7.A O no hydrogen 2.915 N/A LYS 12.A N SER 8.A O no hydrogen 2.888 N/A LYS 13.A N LEU 9.A O no hydrogen 2.923 N/A LYS 13.A NZ ASP 48.A OD1 no hydrogen 3.402 N/A LYS 13.A NZ ASP 48.A OD2 no hydrogen 3.332 N/A GLY 14.A N ILE 10.A O no hydrogen 2.886 N/A LYS 22.A N PRO 18.A O no hydrogen 3.071 N/A LYS 22.A NZ LEU 17.A O no hydrogen 2.424 N/A LYS 22.A NZ GLU 19.A OE2 no hydrogen 2.763 N/A SER 23.A N GLU 19.A O no hydrogen 2.951 N/A SER 23.A OG ASN 20.A O no hydrogen 3.038 N/A GLU 24.A N ASN 20.A O no hydrogen 2.891 N/A LEU 25.A N VAL 21.A O no hydrogen 2.893 N/A TYR 26.A N LYS 22.A O no hydrogen 2.895 N/A GLU 27.A N SER 23.A O no hydrogen 2.950 N/A LYS 28.A N GLU 24.A O no hydrogen 2.889 N/A LEU 29.A N LEU 25.A O no hydrogen 2.879 N/A LYS 30.A N TYR 26.A O no hydrogen 2.914 N/A LYS 31.A N GLU 27.A O no hydrogen 2.953 N/A TYR 32.A N LYS 28.A O no hydrogen 2.906 N/A ASN 33.A N LEU 29.A O no hydrogen 2.850 N/A ASN 33.A ND2 VAL 1.A O no hydrogen 3.489 N/A GLU 34.A N LYS 30.A O no hydrogen 2.914 N/A LYS 35.A N LYS 31.A O no hydrogen 2.941 N/A TYR 36.A N TYR 32.A O no hydrogen 2.612 N/A LEU 38.A N ASN 33.A OD1 no hydrogen 3.327 N/A THR 39.A N GLU 42.A OE1 no hydrogen 2.470 N/A THR 39.A OG1 GLU 42.A OE1 no hydrogen 3.152 N/A ILE 43.A N THR 39.A O no hydrogen 3.129 N/A GLU 44.A N LYS 40.A O no hydrogen 2.921 N/A ALA 45.A N ALA 41.A O no hydrogen 2.911 N/A ILE 46.A N GLU 42.A O no hydrogen 2.887 N/A ILE 47.A N ILE 43.A O no hydrogen 2.941 N/A ASP 48.A N GLU 44.A O no hydrogen 2.917 N/A ASP 49.A N ALA 45.A O no hydrogen 2.890 N/A VAL 50.A N ILE 46.A O no hydrogen 2.907 N/A VAL 51.A N ILE 47.A O no hydrogen 2.961 N/A LYS 52.A N ASP 48.A O no hydrogen 2.916 N/A LYS 52.A NZ GLU 53.A OE2 no hydrogen 3.335 N/A GLU 53.A N ASP 49.A O no hydrogen 2.911 N/A TYR 54.A N VAL 50.A O no hydrogen 2.922 N/A GLU 55.A N VAL 51.A O no hydrogen 2.910 N/A ARG 56.A N LYS 52.A O no hydrogen 2.919 N/A ARG 56.A NE GLU 53.A OE1 no hydrogen 3.373 N/A ARG 56.A NH2 GLU 53.A OE1 no hydrogen 3.266 N/A ARG 56.A NH2 GLU 53.A OE2 no hydrogen 2.615 N/A ALA 57.A N GLU 53.A O no hydrogen 3.157 N/A ALA 57.A N TYR 54.A O no hydrogen 3.220 N/A LEU 58.A N GLU 55.A O no hydrogen 3.512 N/A GLU 63.A N GLU 60.A O no hydrogen 3.089 N/A VAL 65.A N GLU 63.A O no hydrogen 3.073 N/A VAL 68.A N PRO 64.A O no hydrogen 3.366 N/A ALA 69.A N VAL 65.A O no hydrogen 2.888 N/A ALA 70.A N GLY 66.A O no hydrogen 2.940 N/A GLN 71.A N THR 67.A O no hydrogen 2.894 N/A SER 72.A N VAL 68.A O no hydrogen 2.853 N/A SER 72.A OG VAL 68.A O no hydrogen 2.911 N/A ILE 73.A N ALA 69.A O no hydrogen 2.960 N/A GLY 74.A N ALA 70.A O no hydrogen 2.897 N/A GLU 75.A N GLN 71.A O no hydrogen 2.895 N/A SER 77.A N GLY 74.A O no hydrogen 3.221 N/A SER 77.A OG ILE 73.A O no hydrogen 3.083 N/A THR 78.A N GLU 75.A O no hydrogen 3.097 N/A THR 78.A OG1 GLU 75.A O no hydrogen 2.743 N/A GLN 79.A N PRO 76.A O no hydrogen 2.913 N/A MET 80.A N SER 77.A O no hydrogen 3.323 N/A THR 96.A N THR 114.A OG1 no hydrogen 3.220 N/A THR 96.A OG1 SER 113.A OG no hydrogen 3.263 N/A ARG 101.A NH1 GLU 104.A OE1 no hydrogen 2.881 N/A ARG 101.A NH2 ASN 268.A O no hydrogen 3.254 N/A ARG 101.A NH2 GLU 289.A OE2 no hydrogen 2.697 N/A ILE 102.A N GLY 98.A O no hydrogen 3.106 N/A ILE 103.A N LEU 99.A O no hydrogen 2.927 N/A GLU 104.A N PRO 100.A O no hydrogen 2.862 N/A ILE 105.A N ARG 101.A O no hydrogen 2.930 N/A VAL 106.A N ILE 102.A O no hydrogen 2.893 N/A ASP 107.A N ILE 103.A O no hydrogen 2.879 N/A ALA 108.A N ILE 105.A O no hydrogen 2.921 N/A ARG 109.A N GLU 104.A O no hydrogen 3.209 N/A ARG 109.A NE ASN 111.A O no hydrogen 2.810 N/A ARG 109.A NH2 ASN 111.A O no hydrogen 2.819 N/A LYS 110.A NZ HIS 271.A ND1 no hydrogen 3.213 N/A ASN 111.A ND2 ASN 111.A O no hydrogen 2.464 N/A SER 113.A N GLU 104.A OE2 no hydrogen 3.206 N/A SER 113.A OG THR 96.A OG1 no hydrogen 3.263 N/A SER 113.A OG GLU 104.A OE2 no hydrogen 2.598 N/A THR 114.A OG1 THR 114.A O no hydrogen 2.241 N/A VAL 119.A N ILE 244.A O no hydrogen 2.809 N/A ASP 122.A N GLY 259.A O no hydrogen 3.241 N/A HIS 125.A N ASP 122.A O no hydrogen 2.992 N/A HIS 125.A ND1 ASP 122.A OD1 no hydrogen 3.073 N/A ARG 126.A NE LEU 121.A O no hydrogen 3.118 N/A ARG 126.A NH1 GLU 123.A OE1 no hydrogen 2.586 N/A ARG 126.A NH2 LEU 121.A O no hydrogen 2.905 N/A ALA 130.A N ASP 128.A OD1 no hydrogen 3.061 N/A LYS 131.A NZ GLU 124.A O no hydrogen 2.869 N/A ALA 132.A N ASP 128.A O no hydrogen 3.172 N/A ALA 132.A N ARG 129.A O no hydrogen 3.205 N/A GLU 133.A N ARG 129.A O no hydrogen 2.901 N/A ALA 136.A N ALA 132.A O no hydrogen 2.925 N/A ARG 137.A N GLU 133.A O no hydrogen 2.866 N/A ARG 137.A NE GLU 133.A O no hydrogen 3.575 N/A ARG 138.A N GLU 134.A O no hydrogen 2.916 N/A ILE 139.A N ALA 136.A O no hydrogen 3.072 N/A GLU 140.A N ALA 136.A O no hydrogen 3.006 N/A THR 142.A N LYS 225.A O no hydrogen 3.331 N/A THR 142.A OG1 GLU 140.A O no hydrogen 3.456 N/A THR 143.A N ASN 146.A OD1 no hydrogen 2.768 N/A THR 143.A OG1 ASN 146.A OD1 no hydrogen 2.476 N/A THR 143.A OG1 LYS 220.A O no hydrogen 3.254 N/A LEU 147.A N THR 143.A O no hydrogen 3.119 N/A ALA 148.A N GLU 145.A O no hydrogen 3.264 N/A SER 150.A N GLU 163.A O no hydrogen 2.855 N/A THR 152.A OG1 THR 151.A O no hydrogen 2.692 N/A ASP 154.A N GLU 159.A O no hydrogen 2.625 N/A PHE 158.A N LEU 155.A O no hydrogen 3.218 N/A GLU 159.A N ASP 154.A O no hydrogen 2.602 N/A PHE 160.A N VAL 201.A O no hydrogen 2.447 N/A ILE 161.A N THR 152.A O no hydrogen 2.647 N/A VAL 162.A N LEU 199.A O no hydrogen 2.468 N/A GLU 163.A N SER 150.A O no hydrogen 2.857 N/A ILE 164.A N TYR 197.A O no hydrogen 2.827 N/A GLU 167.A N ASP 165.A OD1 no hydrogen 2.850 N/A ARG 168.A N ASP 165.A OD2 no hydrogen 2.579 N/A ARG 168.A NE ASP 165.A OD2 no hydrogen 3.401 N/A ARG 168.A NH1 ASN 146.A O no hydrogen 2.626 N/A LEU 169.A N ASP 165.A O no hydrogen 3.374 N/A GLU 170.A N PRO 166.A O no hydrogen 2.886 N/A ARG 171.A N GLU 167.A O no hydrogen 2.925 N/A ARG 171.A NE GLU 167.A O no hydrogen 3.184 N/A SER 172.A N LEU 169.A O no hydrogen 3.146 N/A SER 172.A OG ARG 168.A O no hydrogen 2.977 N/A SER 172.A OG LEU 169.A O no hydrogen 3.229 N/A LYS 178.A N THR 175.A OG1 no hydrogen 2.828 N/A VAL 179.A N THR 175.A O no hydrogen 2.614 N/A VAL 180.A N MET 176.A O no hydrogen 2.935 N/A LYS 181.A N GLU 177.A O no hydrogen 2.915 N/A GLU 184.A N VAL 180.A O no hydrogen 2.929 N/A SER 185.A OG LYS 182.A O no hydrogen 3.216 N/A SER 186.A N LYS 182.A O no hydrogen 2.900 N/A SER 186.A OG LYS 182.A O no hydrogen 2.328 N/A SER 186.A OG HIS 222.A NE2 no hydrogen 3.248 N/A PHE 187.A N LEU 183.A O no hydrogen 3.360 N/A LYS 188.A NZ SER 185.A O no hydrogen 3.100 N/A SER 189.A OG LYS 188.A O no hydrogen 2.669 N/A GLU 191.A N ARG 202.A O no hydrogen 3.060 N/A ASP 195.A N THR 198.A O no hydrogen 3.094 N/A THR 198.A N ASP 195.A O no hydrogen 2.855 N/A ILE 200.A N GLU 193.A O no hydrogen 2.680 N/A VAL 201.A N PHE 160.A O no hydrogen 2.359 N/A LYS 204.A N SER 189.A O no hydrogen 2.802 N/A ASP 207.A N LYS 205.A O no hydrogen 2.950 N/A LYS 208.A NZ ASP 207.A OD2 no hydrogen 2.660 N/A LEU 212.A N LYS 208.A O no hydrogen 3.275 N/A ARG 213.A N ILE 209.A O no hydrogen 2.940 N/A ARG 214.A N SER 210.A O no hydrogen 2.876 N/A ARG 214.A NE SER 210.A O no hydrogen 2.984 N/A ARG 214.A NH2 SER 210.A OG no hydrogen 2.596 N/A PHE 215.A N ASP 211.A O no hydrogen 2.901 N/A ALA 216.A N LEU 212.A O no hydrogen 2.900 N/A GLU 217.A N ARG 213.A O no hydrogen 2.915 N/A LYS 218.A N ARG 214.A O no hydrogen 2.885 N/A ILE 219.A N PHE 215.A O no hydrogen 2.893 N/A LYS 220.A N ALA 216.A O no hydrogen 2.908 N/A LYS 220.A NZ ALA 216.A O no hydrogen 2.941 N/A LYS 220.A NZ GLU 217.A OE2 no hydrogen 2.992 N/A LYS 221.A N GLU 217.A O no hydrogen 2.911 N/A HIS 222.A N LYS 218.A O no hydrogen 2.881 N/A ARG 223.A NE LYS 225.A O no hydrogen 3.219 N/A ARG 223.A NE GLY 226.A O no hydrogen 3.147 N/A ARG 223.A NH2 GLY 226.A O no hydrogen 3.069 N/A LEU 224.A N THR 142.A O no hydrogen 3.089 N/A LYS 225.A NZ ARG 137.A O no hydrogen 2.532 N/A LEU 227.A N ILE 139.A O no hydrogen 3.105 N/A VAL 230.A N LEU 227.A O no hydrogen 3.412 N/A THR 233.A OG1 GLU 140.A OE1 no hydrogen 3.287 N/A ILE 234.A N TYR 245.A O no hydrogen 2.807 N/A ARG 236.A N VAL 243.A O no hydrogen 3.061 N/A GLU 238.A N GLU 241.A O no hydrogen 2.873 N/A GLU 241.A N GLU 238.A O no hydrogen 2.881 N/A VAL 243.A N ARG 236.A O no hydrogen 2.864 N/A ILE 244.A N VAL 119.A O no hydrogen 2.890 N/A TYR 245.A N ILE 234.A O no hydrogen 3.048 N/A THR 246.A N MET 117.A O no hydrogen 3.280 N/A THR 246.A OG1 GLY 248.A O no hydrogen 3.091 N/A GLU 247.A N LYS 232.A O no hydrogen 2.698 N/A SER 249.A OG GLU 272.A OE1 no hydrogen 2.732 N/A ASN 250.A ND2 SER 228.A O no hydrogen 2.594 N/A PHE 251.A N GLU 272.A OE2 no hydrogen 2.425 N/A GLN 253.A NE2 ASN 250.A OD1 no hydrogen 3.127 N/A VAL 254.A N ASN 250.A O no hydrogen 3.299 N/A LEU 255.A N PHE 251.A O no hydrogen 2.879 N/A LYS 256.A N GLN 253.A O no hydrogen 3.093 N/A LYS 256.A NZ GLN 253.A OE1 no hydrogen 2.658 N/A VAL 257.A N VAL 254.A O no hydrogen 3.352 N/A ASP 261.A N TYR 120.A O no hydrogen 3.016 N/A THR 263.A N ASP 261.A OD1 no hydrogen 3.470 N/A THR 263.A OG1 ASP 261.A OD1 no hydrogen 3.109 N/A ARG 264.A N ASP 261.A O no hydrogen 3.376 N/A ARG 264.A NH1 ASP 261.A OD2 no hydrogen 2.423 N/A ARG 264.A NH2 GLU 241.A OE1 no hydrogen 2.718 N/A ARG 264.A NH2 GLU 241.A OE2 no hydrogen 3.284 N/A THR 265.A OG1 ASP 261.A O no hydrogen 3.011 N/A ARG 266.A N THR 118.A O no hydrogen 2.887 N/A ARG 266.A NH1 ASP 288.A OD1 no hydrogen 3.378 N/A ARG 266.A NH1 ASP 288.A OD2 no hydrogen 2.259 N/A THR 267.A OG1 ARG 266.A O no hydrogen 2.569 N/A ASN 268.A N MET 116.A O no hydrogen 2.927 N/A ASN 269.A ND2 LYS 110.A O no hydrogen 3.269 N/A HIS 271.A NE2 ALA 108.A O no hydrogen 3.170 N/A GLU 272.A N ASN 269.A OD1 no hydrogen 3.420 N/A ILE 273.A N ASN 269.A O no hydrogen 3.183 N/A ALA 274.A N ILE 270.A O no hydrogen 2.896 N/A GLU 275.A N HIS 271.A O no hydrogen 2.910 N/A VAL 276.A N GLU 272.A O no hydrogen 2.947 N/A VAL 276.A N ILE 273.A O no hydrogen 3.352 N/A LEU 277.A N ILE 273.A O no hydrogen 2.777 N/A GLY 278.A N ALA 274.A O no hydrogen 2.985 N/A ALA 282.A N GLY 278.A O no hydrogen 3.086 N/A ARG 283.A N ILE 279.A O no hydrogen 2.921 N/A ARG 283.A NE ASP 311.A OD1 no hydrogen 2.442 N/A ARG 283.A NH2 ASP 311.A OD2 no hydrogen 2.809 N/A ASN 284.A N GLU 280.A O no hydrogen 2.940 N/A ALA 285.A N ALA 281.A O no hydrogen 2.867 N/A ILE 286.A N ALA 282.A O no hydrogen 2.902 N/A ILE 287.A N ARG 283.A O no hydrogen 2.958 N/A ASP 288.A N ASN 284.A O no hydrogen 2.951 N/A GLU 289.A N ALA 285.A O no hydrogen 2.861 N/A ILE 290.A N ILE 286.A O no hydrogen 2.962 N/A VAL 291.A N ILE 287.A O no hydrogen 2.949 N/A SER 292.A N ASP 288.A O no hydrogen 2.888 N/A SER 292.A OG ASP 288.A O no hydrogen 3.566 N/A SER 292.A OG GLU 289.A O no hydrogen 2.862 N/A THR 293.A N GLU 289.A O no hydrogen 2.913 N/A THR 293.A OG1 GLU 289.A O no hydrogen 2.721 N/A MET 294.A N ILE 290.A O no hydrogen 2.933 N/A GLN 295.A N VAL 291.A O no hydrogen 2.890 N/A GLU 296.A N SER 292.A O no hydrogen 2.918 N/A GLN 297.A N MET 294.A O no hydrogen 3.262 N/A GLY 298.A N GLN 295.A O no hydrogen 3.133 N/A LEU 299.A N MET 294.A O no hydrogen 3.293 N/A ARG 304.A N ASP 302.A OD2 no hydrogen 3.376 N/A ARG 304.A NH1 ASP 302.A OD2 no hydrogen 2.762 N/A MET 307.A N ILE 303.A O no hydrogen 2.907 N/A LEU 308.A N ARG 304.A O no hydrogen 2.901 N/A VAL 309.A N HIS 305.A O no hydrogen 2.980 N/A ALA 310.A N ILE 306.A O no hydrogen 2.912 N/A ASP 311.A N MET 307.A O no hydrogen 2.871 N/A MET 312.A N LEU 308.A O no hydrogen 2.949 N/A MET 313.A N VAL 309.A O no hydrogen 2.907 N/A THR 314.A N ALA 310.A O no hydrogen 2.916 N/A THR 314.A OG1 ALA 310.A O no hydrogen 2.994 N/A ARG 320.A N MET 313.A O no hydrogen 3.436 N/A ARG 320.A NH2 ASP 316.A OD2 no hydrogen 3.097 N/A ARG 324.A NH1 GLU 341.A OE1 no hydrogen 2.322 N/A GLY 326.A N GLY 323.A O no hydrogen 3.131 N/A VAL 327.A N PRO 321.A O no hydrogen 2.905 N/A GLU 330.A N GLY 326.A O no hydrogen 3.057 N/A GLU 330.A N VAL 327.A O no hydrogen 3.275 N/A LYS 331.A N VAL 328.A O no hydrogen 3.080 N/A SER 333.A OG ASP 357.A OD1 no hydrogen 2.942 N/A SER 333.A OG ASP 357.A OD2 no hydrogen 2.667 N/A LEU 335.A N ASP 357.A OD2 no hydrogen 2.717 N/A ALA 336.A N SER 333.A OG no hydrogen 3.244 N/A ARG 337.A N SER 333.A O no hydrogen 3.403 N/A ARG 337.A NH1 LYS 331.A O no hydrogen 2.685 N/A ARG 337.A NH1 SER 332.A O no hydrogen 3.293 N/A ALA 338.A N VAL 334.A O no hydrogen 2.905 N/A ALA 339.A N LEU 335.A O no hydrogen 2.899 N/A PHE 340.A N ARG 337.A O no hydrogen 3.182 N/A THR 343.A OG1 ALA 338.A O no hydrogen 2.544 N/A THR 343.A OG1 GLU 341.A O no hydrogen 2.970 N/A GLN 345.A N GLN 345.A OE1 no hydrogen 2.550 N/A HIS 346.A ND1 ILE 342.A O no hydrogen 2.883 N/A LEU 347.A N THR 343.A O no hydrogen 3.061 N/A PHE 348.A N VAL 344.A O no hydrogen 2.912 N/A GLU 349.A N GLN 345.A O no hydrogen 2.926 N/A ALA 350.A N HIS 346.A O no hydrogen 2.884 N/A ALA 351.A N LEU 347.A O no hydrogen 2.921 N/A GLU 352.A N PHE 348.A O no hydrogen 2.925 N/A LYS 353.A N GLU 349.A O no hydrogen 3.135 N/A GLU 355.A N ALA 350.A O no hydrogen 3.010 N/A LEU 359.A N ASP 357.A OD1 no hydrogen 3.224 N/A GLY 361.A N GLU 364.A OE2 no hydrogen 2.816 N/A GLU 364.A N GLU 364.A OE1 no hydrogen 2.660 N/A ASN 365.A ND2 LEU 359.A O no hydrogen 3.484 N/A VAL 366.A N VAL 362.A O no hydrogen 3.101 N/A LEU 367.A N ILE 363.A O no hydrogen 2.931 N/A ILE 368.A N GLU 364.A O no hydrogen 2.938 N/A GLY 369.A N ASN 365.A O no hydrogen 2.983 N/A GLN 370.A N ASN 365.A O no hydrogen 2.873 N/A VAL 374.A N VAL 372.A O no hydrogen 2.968 N/A GLY 375.A N GLY 62.A O no hydrogen 2.846 N/A GLY 377.A N VAL 374.A O no hydrogen 2.880 N/A MET 378.A N GLY 375.A O no hydrogen 3.372 N/A LYS 380.A NZ MET 378.A O no hydrogen 3.053 N/A