Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8cuk_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 4.A N ILE 291.A O no hydrogen 2.866 N/A LEU 6.A N SER 292.A O no hydrogen 2.899 N/A GLU 8.A N THR 328.A O no hydrogen 2.653 N/A ILE 10.A N ARG 326.A O no hydrogen 2.826 N/A ILE 12.A N MET 324.A O no hydrogen 2.741 N/A ASP 14.A N GLY 322.A O no hydrogen 2.960 N/A ASN 16.A N ASP 14.A OD1 no hydrogen 2.783 N/A ASN 16.A ND2 SER 21.A O no hydrogen 2.772 N/A ASN 16.A ND2 SER 57.A O no hydrogen 3.576 N/A PHE 17.A N ASP 14.A O no hydrogen 2.876 N/A GLY 19.A N ASN 16.A O no hydrogen 3.094 N/A LEU 23.A N ASP 14.A OD2 no hydrogen 2.741 N/A TYR 24.A OH ILE 12.A O no hydrogen 3.282 N/A SER 25.A N ASP 14.A OD2 no hydrogen 3.135 N/A SER 25.A OG ASP 14.A OD2 no hydrogen 2.727 N/A ASP 26.A N LEU 23.A O no hydrogen 3.014 N/A THR 28.A N ASP 26.A OD1 no hydrogen 3.037 N/A THR 28.A OG1 ASP 26.A OD1 no hydrogen 2.795 N/A LEU 29.A N ASP 26.A O no hydrogen 3.028 N/A CYS 30.A N ALA 43.A O no hydrogen 2.837 N/A CYS 30.A SG ALA 43.A O no hydrogen 3.422 N/A CYS 30.A SG GLN 71.A OE1 no hydrogen 3.221 N/A CYS 30.A SG ILE 72.A O no hydrogen 3.292 N/A THR 33.A N ILE 41.A O no hydrogen 2.824 N/A VAL 35.A N THR 39.A O no hydrogen 2.877 N/A GLN 38.A N ASP 36.A OD1 no hydrogen 2.860 N/A THR 39.A N ASP 36.A O no hydrogen 3.071 N/A THR 39.A OG1 ASP 36.A OD1 no hydrogen 2.905 N/A THR 39.A OG1 ASP 36.A OD2 no hydrogen 3.430 N/A LEU 40.A N VAL 52.A O no hydrogen 2.787 N/A ILE 41.A N THR 33.A O no hydrogen 2.780 N/A ILE 42.A N LYS 50.A O no hydrogen 2.907 N/A ALA 43.A N ALA 31.A O no hydrogen 2.863 N/A VAL 44.A N ILE 48.A O no hydrogen 2.959 N/A ASN 45.A N THR 28.A OG1 no hydrogen 3.110 N/A ASN 47.A N ASN 45.A O no hydrogen 2.759 N/A ASN 47.A ND2 PRO 67.A O no hydrogen 2.794 N/A ASN 47.A ND2 PHE 70.A O no hydrogen 3.638 N/A ILE 48.A N VAL 44.A O no hydrogen 2.961 N/A ILE 49.A N PHE 63.A O no hydrogen 2.776 N/A LYS 50.A N ILE 42.A O no hydrogen 2.863 N/A VAL 51.A N HIS 61.A O no hydrogen 2.879 N/A VAL 52.A N LEU 40.A O no hydrogen 2.625 N/A LYS 53.A N GLN 58.A O no hydrogen 2.992 N/A LYS 53.A NZ THR 39.A OG1 no hydrogen 2.937 N/A LEU 54.A N GLN 38.A O no hydrogen 2.906 N/A GLN 56.A N LYS 53.A O no hydrogen 3.167 N/A SER 57.A N LEU 54.A O no hydrogen 3.108 N/A GLN 58.A N LYS 53.A O no hydrogen 3.466 N/A ILE 60.A N VAL 51.A O no hydrogen 2.941 N/A HIS 61.A NE2 PRO 105.A O no hydrogen 2.669 N/A PHE 63.A N ILE 49.A O no hydrogen 3.029 N/A GLN 64.A NE2 PHE 66.A O no hydrogen 2.749 N/A SER 65.A N ASN 47.A O no hydrogen 2.957 N/A SER 65.A OG ASN 47.A O no hydrogen 3.315 N/A PHE 70.A N PRO 67.A O no hydrogen 3.051 N/A GLN 71.A N GLU 88.A O no hydrogen 2.904 N/A ILE 72.A N SER 46.A O no hydrogen 2.785 N/A THR 73.A N LEU 86.A O no hydrogen 2.886 N/A THR 73.A OG1 LEU 86.A O no hydrogen 3.376 N/A THR 73.A OG1 GLU 88.A OE1 no hydrogen 2.766 N/A PHE 74.A N LEU 86.A O no hydrogen 3.329 N/A LYS 76.A N VAL 84.A O no hydrogen 2.813 N/A LYS 76.A NZ VAL 129.A O no hydrogen 3.501 N/A ILE 78.A N PHE 82.A O no hydrogen 2.914 N/A GLU 81.A N ILE 78.A O no hydrogen 3.085 N/A PHE 82.A N ILE 78.A O no hydrogen 3.115 N/A LEU 83.A N TYR 99.A O no hydrogen 2.933 N/A VAL 84.A N LYS 76.A O no hydrogen 2.738 N/A ALA 85.A N ARG 97.A O no hydrogen 2.930 N/A LEU 86.A N PHE 74.A O no hydrogen 2.946 N/A ALA 87.A N LEU 95.A O no hydrogen 2.970 N/A GLU 88.A N GLN 71.A O no hydrogen 2.865 N/A SER 89.A OG ASP 69.A O no hydrogen 2.497 N/A GLY 91.A N ASN 122.A O no hydrogen 2.826 N/A LYS 92.A N SER 89.A O no hydrogen 2.933 N/A LYS 92.A NZ ASP 69.A OD2 no hydrogen 2.775 N/A SER 94.A N LEU 117.A O no hydrogen 3.005 N/A LEU 95.A N ALA 87.A O no hydrogen 3.017 N/A ILE 96.A N VAL 115.A O no hydrogen 2.775 N/A ARG 97.A N ALA 85.A O no hydrogen 2.853 N/A ARG 97.A NE GLN 114.A OE1 no hydrogen 2.855 N/A ARG 97.A NH1 SER 65.A O no hydrogen 2.714 N/A ARG 97.A NH1 GLU 108.A OE2 no hydrogen 3.193 N/A ARG 97.A NH2 GLN 114.A OE1 no hydrogen 2.982 N/A VAL 98.A N SER 113.A O no hydrogen 2.872 N/A TYR 99.A N LEU 83.A O no hydrogen 2.755 N/A LEU 101.A N GLU 81.A O no hydrogen 3.037 N/A GLU 102.A N GLU 102.A OE1 no hydrogen 2.418 N/A LYS 103.A N LYS 100.A O no hydrogen 3.048 N/A ARG 107.A NH1 ASN 106.A OD1 no hydrogen 3.463 N/A GLN 109.A N GLN 109.A OE1 no hydrogen 2.724 N/A LEU 110.A N ARG 107.A O no hydrogen 3.397 N/A HIS 112.A N VAL 98.A O no hydrogen 2.828 N/A HIS 112.A NE2 SER 155.A O no hydrogen 2.582 N/A SER 113.A N VAL 98.A O no hydrogen 3.301 N/A SER 113.A OG ASP 157.A OD1 no hydrogen 2.990 N/A VAL 115.A N ILE 96.A O no hydrogen 2.868 N/A LEU 117.A N SER 94.A O no hydrogen 2.858 N/A ASN 119.A N ASN 122.A OD1 no hydrogen 2.607 N/A ASN 119.A ND2 ASN 144.A OD1 no hydrogen 3.092 N/A ASN 122.A N ASN 119.A O no hydrogen 2.716 N/A THR 123.A N ASN 121.A OD1 no hydrogen 3.327 N/A THR 123.A OG1 ASN 121.A OD1 no hydrogen 3.230 N/A ILE 126.A N GLU 88.A OE2 no hydrogen 2.776 N/A SER 127.A N GLY 141.A O no hydrogen 2.723 N/A SER 127.A OG GLY 141.A O no hydrogen 3.033 N/A SER 127.A OG ILE 174.A O no hydrogen 2.721 N/A VAL 128.A N GLY 141.A O no hydrogen 3.215 N/A SER 130.A N VAL 139.A O no hydrogen 2.906 N/A SER 132.A N CYS 137.A O no hydrogen 2.917 N/A SER 132.A OG ASP 134.A OD1 no hydrogen 2.690 N/A SER 132.A OG CYS 137.A O no hydrogen 3.462 N/A LEU 135.A N SER 132.A O no hydrogen 3.053 N/A SER 136.A N ASP 134.A OD1 no hydrogen 3.088 N/A SER 136.A OG ASP 134.A OD1 no hydrogen 2.991 N/A SER 136.A OG ASP 134.A OD2 no hydrogen 3.297 N/A CYS 137.A N SER 132.A OG no hydrogen 3.260 N/A ILE 138.A N ILE 150.A O no hydrogen 2.860 N/A VAL 139.A N SER 130.A O no hydrogen 2.895 N/A VAL 140.A N ILE 148.A O no hydrogen 2.965 N/A GLY 141.A N VAL 128.A O no hydrogen 2.807 N/A PHE 142.A N LYS 146.A O no hydrogen 2.985 N/A ILE 143.A N PRO 125.A O no hydrogen 3.000 N/A ASN 144.A ND2 ASN 119.A OD1 no hydrogen 3.298 N/A GLY 145.A N PHE 142.A O no hydrogen 3.199 N/A LYS 146.A NZ ASN 119.A OD1 no hydrogen 3.060 N/A ILE 147.A N TYR 166.A O no hydrogen 2.899 N/A ILE 148.A N VAL 140.A O no hydrogen 2.870 N/A LEU 149.A N ARG 163.A O no hydrogen 2.813 N/A ILE 150.A N ILE 138.A O no hydrogen 2.740 N/A ARG 151.A N GLN 161.A O no hydrogen 2.902 N/A ARG 151.A NH1 THR 199.A O no hydrogen 2.980 N/A GLY 152.A N SER 136.A O no hydrogen 3.153 N/A ILE 154.A N GLY 152.A O no hydrogen 2.865 N/A SER 155.A OG ASP 153.A OD1 no hydrogen 3.561 N/A ARG 156.A N ASP 153.A O no hydrogen 3.304 N/A ASP 157.A N ILE 154.A O no hydrogen 3.013 N/A ARG 158.A N ASP 153.A O no hydrogen 3.143 N/A GLN 161.A N ARG 151.A O no hydrogen 2.729 N/A GLN 162.A NE2 GLU 116.A O no hydrogen 2.634 N/A ARG 163.A N LEU 149.A O no hydrogen 2.869 N/A ARG 163.A NH1 GLY 201.A O no hydrogen 2.884 N/A ILE 165.A N ILE 147.A O no hydrogen 3.083 N/A TYR 166.A OH ASP 168.A OD1 no hydrogen 2.702 N/A ASP 168.A N GLY 145.A O no hydrogen 2.728 N/A LYS 171.A N ASP 168.A O no hydrogen 2.882 N/A GLU 172.A N ASP 168.A OD2 no hydrogen 2.973 N/A ILE 174.A N PHE 142.A O no hydrogen 3.076 N/A THR 175.A N ALA 189.A O no hydrogen 2.769 N/A THR 175.A OG1 LEU 217.A O no hydrogen 2.720 N/A PHE 178.A N PHE 187.A O no hydrogen 2.939 N/A LEU 179.A N SER 130.A OG no hydrogen 2.963 N/A ASN 180.A N ALA 185.A O no hydrogen 3.042 N/A ASN 180.A ND2 THR 184.A OG1 no hydrogen 3.377 N/A ASN 180.A ND2 SER 244.A OG no hydrogen 2.915 N/A ASN 181.A N ASN 229.A OD1 no hydrogen 3.012 N/A ASN 181.A ND2 PRO 226.A O no hydrogen 2.814 N/A ALA 183.A N ASN 180.A O no hydrogen 2.965 N/A THR 184.A N ASP 182.A OD1 no hydrogen 3.266 N/A THR 184.A OG1 ASP 182.A OD1 no hydrogen 2.641 N/A ALA 185.A N ASN 180.A OD1 no hydrogen 3.242 N/A CYS 186.A N PHE 197.A O no hydrogen 2.701 N/A CYS 186.A SG.B PHE 187.A O no hydrogen 3.655 N/A PHE 187.A N PHE 178.A O no hydrogen 2.717 N/A ALA 188.A N LEU 195.A O no hydrogen 2.841 N/A ALA 189.A N ALA 176.A O no hydrogen 3.141 N/A THR 190.A N ARG 193.A O no hydrogen 2.968 N/A THR 190.A OG1 GLU 172.A OE2 no hydrogen 3.364 N/A SER 192.A N THR 190.A OG1 no hydrogen 3.147 N/A SER 192.A OG GLU 172.A OE1 no hydrogen 3.175 N/A SER 192.A OG GLU 172.A OE2 no hydrogen 2.340 N/A ARG 193.A N THR 190.A OG1 no hydrogen 3.112 N/A ARG 193.A NH1 TYR 166.A OH no hydrogen 3.196 N/A ILE 194.A N ASN 212.A O no hydrogen 2.994 N/A LEU 195.A N ALA 188.A O no hydrogen 2.684 N/A LEU 196.A N LEU 209.A O no hydrogen 2.901 N/A PHE 197.A N CYS 186.A O no hydrogen 2.952 N/A ASN 198.A N SER 208.A OG no hydrogen 3.126 N/A ASN 198.A ND2 SER 208.A OG no hydrogen 2.985 N/A THR 199.A N THR 184.A O no hydrogen 2.911 N/A THR 199.A OG1 ALA 183.A O no hydrogen 2.652 N/A THR 200.A N ASN 198.A OD1 no hydrogen 2.785 N/A THR 200.A OG1 ASN 198.A OD1 no hydrogen 2.641 N/A ARG 202.A NH1 GLY 201.A O no hydrogen 3.078 N/A ASN 203.A ND2 ILE 165.A O no hydrogen 2.746 N/A ASN 203.A ND2 ARG 206.A O no hydrogen 2.806 N/A ARG 206.A N ASN 203.A O no hydrogen 2.902 N/A SER 208.A N LEU 196.A O no hydrogen 2.647 N/A LEU 209.A N LEU 196.A O no hydrogen 3.107 N/A LEU 211.A N ILE 194.A O no hydrogen 2.829 N/A ASN 212.A N ILE 194.A O no hydrogen 3.090 N/A ASN 212.A ND2 GLU 240.A OE1 no hydrogen 3.345 N/A LYS 214.A N ASN 212.A OD1 no hydrogen 2.854 N/A ASN 215.A N ASN 212.A OD1 no hydrogen 2.986 N/A LEU 217.A N THR 190.A O no hydrogen 2.815 N/A CYS 221.A N ASP 218.A O no hydrogen 3.020 N/A CYS 221.A SG LEU 219.A O no hydrogen 3.710 N/A SER 223.A N ILE 232.A O no hydrogen 2.961 N/A ASN 225.A N GLU 230.A O no hydrogen 2.867 N/A ASN 225.A ND2 LYS 266.A O no hydrogen 2.864 N/A ALA 227.A N ASN 225.A OD1 no hydrogen 3.139 N/A THR 228.A N ASN 225.A O no hydrogen 3.248 N/A THR 228.A OG1 GLU 230.A OE1 no hydrogen 3.108 N/A GLU 230.A N ASN 225.A O no hydrogen 3.267 N/A PHE 231.A N PHE 242.A O no hydrogen 2.844 N/A ILE 232.A N SER 223.A O no hydrogen 2.804 N/A CYS 233.A N GLU 240.A O no hydrogen 2.789 N/A CYS 234.A N CYS 221.A O no hydrogen 2.997 N/A CYS 234.A SG LEU 235.A O no hydrogen 3.748 N/A LEU 235.A N PHE 238.A O no hydrogen 2.805 N/A ILE 239.A N PHE 251.A O no hydrogen 3.085 N/A GLU 240.A N CYS 233.A O no hydrogen 2.798 N/A PHE 241.A N HIS 249.A O no hydrogen 2.745 N/A PHE 242.A N PHE 231.A O no hydrogen 2.949 N/A SER 243.A N LYS 247.A O no hydrogen 2.940 N/A SER 243.A OG SER 245.A OG no hydrogen 2.927 N/A SER 245.A N SER 243.A OG no hydrogen 3.122 N/A SER 245.A OG SER 243.A OG no hydrogen 2.927 N/A GLY 246.A N SER 243.A O no hydrogen 2.892 N/A LYS 247.A N SER 243.A OG no hydrogen 3.240 N/A LYS 248.A NZ GLU 240.A OE2 no hydrogen 2.282 N/A LYS 248.A NZ GLN 250.A OE1 no hydrogen 3.248 N/A HIS 249.A N PHE 241.A O no hydrogen 3.175 N/A HIS 249.A NE2 GLU 230.A OE2 no hydrogen 2.982 N/A PHE 251.A N ILE 239.A O no hydrogen 3.100 N/A PHE 253.A N ASN 237.A O no hydrogen 3.036 N/A LEU 255.A N SER 236.A O no hydrogen 2.994 N/A SER 256.A N ASP 254.A OD1 no hydrogen 3.498 N/A SER 256.A OG ASP 254.A OD1 no hydrogen 2.649 N/A ARG 258.A N LEU 255.A O no hydrogen 3.076 N/A ARG 258.A NH1 LEU 255.A O no hydrogen 2.959 N/A LYS 259.A N VAL 272.A O no hydrogen 2.773 N/A ILE 261.A N ASN 220.A O no hydrogen 2.861 N/A PHE 262.A N LEU 270.A O no hydrogen 2.879 N/A CYS 263.A N SER 223.A OG no hydrogen 2.988 N/A CYS 263.A SG ASP 265.A O no hydrogen 3.267 N/A VAL 264.A N HIS 268.A O no hydrogen 2.931 N/A LYS 266.A NZ ASP 267.A OD2 no hydrogen 3.280 N/A ASP 267.A N ASP 265.A OD1 no hydrogen 3.174 N/A HIS 268.A N ASP 265.A OD1 no hydrogen 2.963 N/A HIS 268.A ND1 ASP 265.A OD1 no hydrogen 2.739 N/A ILE 269.A N ILE 284.A O no hydrogen 2.920 N/A LEU 270.A N PHE 262.A O no hydrogen 2.763 N/A ILE 271.A N PHE 282.A O no hydrogen 2.750 N/A VAL 272.A N ARG 260.A O no hydrogen 2.804 N/A THR 273.A N ARG 280.A O no hydrogen 2.938 N/A THR 273.A OG1 ARG 280.A O no hydrogen 3.472 N/A GLU 274.A N LEU 257.A O no hydrogen 2.931 N/A GLU 275.A N ILE 278.A O no hydrogen 2.787 N/A ILE 278.A N GLU 275.A O no hydrogen 2.673 N/A ASN 279.A N VAL 297.A O no hydrogen 3.083 N/A ASN 279.A ND2 SER 299.A O no hydrogen 3.099 N/A ARG 280.A N THR 273.A O no hydrogen 2.910 N/A ARG 280.A NE GLU 275.A OE2 no hydrogen 2.633 N/A ARG 280.A NH1 ASN 294.A OD1 no hydrogen 2.732 N/A ARG 280.A NH2 GLU 275.A OE1 no hydrogen 3.165 N/A ILE 281.A N PHE 295.A O no hydrogen 2.665 N/A PHE 282.A N ILE 271.A O no hydrogen 2.879 N/A ILE 283.A N LEU 293.A O no hydrogen 2.983 N/A ILE 284.A N ILE 269.A O no hydrogen 2.840 N/A ASP 285.A N ILE 290.A O no hydrogen 2.796 N/A ALA 286.A N ASP 267.A O no hydrogen 2.832 N/A LYS 287.A N ASP 285.A OD1 no hydrogen 3.032 N/A ASN 288.A N ASP 285.A OD1 no hydrogen 3.133 N/A ASN 288.A ND2 ASP 285.A OD2 no hydrogen 2.704 N/A LYS 289.A N ASP 285.A O no hydrogen 2.747 N/A ILE 291.A N ARG 2.A O no hydrogen 2.903 N/A SER 292.A N ILE 283.A O no hydrogen 2.650 N/A ASN 294.A ND2 GLN 3.A OE1 no hydrogen 2.872 N/A PHE 295.A N ILE 281.A O no hydrogen 3.055 N/A VAL 297.A N ASN 279.A O no hydrogen 2.815 N/A SER 299.A OG ALA 300.A O no hydrogen 3.536 N/A SER 299.A OG SER 320.A OG no hydrogen 3.028 N/A ILE 302.A N LEU 318.A O no hydrogen 2.737 N/A ILE 304.A N ASP 303.A OD1 no hydrogen 2.703 N/A PHE 305.A N TYR 316.A O no hydrogen 3.107 N/A SER 306.A OG ILE 314.A O no hydrogen 3.171 N/A THR 307.A N ILE 314.A O no hydrogen 3.048 N/A THR 307.A OG1 TYR 316.A OH no hydrogen 3.006 N/A GLN 309.A N GLN 309.A OE1 no hydrogen 2.809 N/A GLN 309.A NE2 VAL 35.A O no hydrogen 2.910 N/A ASN 313.A ND2 VAL 264.A O no hydrogen 2.980 N/A ILE 314.A N THR 307.A O no hydrogen 2.884 N/A THR 315.A N ILE 327.A O no hydrogen 2.936 N/A TYR 316.A N PHE 305.A O no hydrogen 2.743 N/A TYR 316.A OH THR 307.A OG1 no hydrogen 3.006 N/A LEU 317.A N HIS 325.A O no hydrogen 2.901 N/A LEU 318.A N ASP 303.A O no hydrogen 3.028 N/A THR 319.A N VAL 323.A O no hydrogen 2.866 N/A SER 320.A N SER 299.A OG no hydrogen 3.252 N/A SER 320.A N ALA 300.A O no hydrogen 2.786 N/A SER 320.A OG SER 299.A OG no hydrogen 3.028 N/A SER 320.A OG ALA 300.A O no hydrogen 3.153 N/A SER 320.A OG GLU 321.A OE2 no hydrogen 3.437 N/A GLY 322.A N THR 319.A O no hydrogen 3.408 N/A MET 324.A N ILE 12.A O no hydrogen 2.767 N/A HIS 325.A N LEU 317.A O no hydrogen 2.877 N/A HIS 325.A ND1 ASN 9.A OD1 no hydrogen 3.100 N/A ARG 326.A N ILE 10.A O no hydrogen 3.143 N/A ILE 327.A N THR 315.A O no hydrogen 2.778 N/A THR 328.A N GLU 8.A O no hydrogen 2.850 N/A LYS 330.A N LEU 6.A O no hydrogen 3.247 N/A LYS 330.A NZ GLN 5.A O no hydrogen 3.498 N/A