Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8cxg_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 1.A N ASP 42.A OD2 no hydrogen 3.492 N/A ARG 2.A NH1 GLU 44.A OE1 no hydrogen 2.472 N/A ARG 2.A NH2 GLU 44.A OE1 no hydrogen 2.760 N/A SER 7.A OG VAL 6.A O no hydrogen 2.364 N/A ARG 9.A NH1 GLU 368.A OE2 no hydrogen 3.282 N/A ARG 9.A NH2 GLU 368.A OE1 no hydrogen 3.180 N/A ARG 9.A NH2 GLU 368.A OE2 no hydrogen 2.527 N/A ASP 10.A N CYS 30.A O no hydrogen 3.273 N/A VAL 12.A N THR 32.A O no hydrogen 3.095 N/A GLY 14.A N MET 34.A O no hydrogen 3.465 N/A THR 19.A N SER 16.A O no hydrogen 3.207 N/A THR 19.A OG1 SER 16.A O no hydrogen 2.594 N/A VAL 21.A N LEU 284.A O no hydrogen 3.087 N/A VAL 23.A N CYS 282.A O no hydrogen 3.042 N/A LEU 25.A N LEU 280.A O no hydrogen 2.444 N/A VAL 31.A N ILE 43.A O no hydrogen 2.955 N/A THR 32.A N ASP 10.A O no hydrogen 3.275 N/A VAL 33.A N VAL 41.A O no hydrogen 2.835 N/A MET 34.A N VAL 12.A O no hydrogen 3.169 N/A LYS 38.A NZ LEU 289.A O no hydrogen 3.064 N/A VAL 41.A N VAL 33.A O no hydrogen 2.973 N/A ASP 42.A N SER 142.A O no hydrogen 2.865 N/A ILE 43.A N VAL 31.A O no hydrogen 2.863 N/A GLU 44.A N MET 140.A O no hydrogen 2.920 N/A VAL 46.A N ARG 138.A O no hydrogen 3.154 N/A THR 48.A N LEU 275.A O no hydrogen 3.057 N/A THR 48.A OG1 LEU 275.A O no hydrogen 3.038 N/A THR 49.A N GLU 136.A O no hydrogen 2.898 N/A THR 49.A OG1 GLU 136.A O no hydrogen 3.489 N/A THR 49.A OG1 GLU 136.A OE1 no hydrogen 3.361 N/A VAL 50.A N GLY 273.A O no hydrogen 2.880 N/A SER 51.A OG ASN 134.A O no hydrogen 2.465 N/A VAL 56.A N GLY 127.A O no hydrogen 2.840 N/A ARG 57.A NH2 TYR 59.A OH no hydrogen 3.260 N/A TYR 59.A OH PHE 209.A O no hydrogen 3.083 N/A CYS 60.A N PRO 215.A O no hydrogen 2.957 N/A SER 64.A N ALA 120.A O no hydrogen 2.805 N/A SER 66.A OG ASP 67.A OD1 no hydrogen 2.821 N/A ASP 67.A N SER 66.A OG no hydrogen 2.585 N/A ALA 69.A N CYS 116.A O no hydrogen 2.912 N/A ASP 71.A N VAL 114.A O no hydrogen 2.915 N/A ARG 73.A NE ASP 71.A OD1 no hydrogen 3.562 N/A ARG 73.A NE SER 72.A O no hydrogen 3.443 N/A ARG 73.A NH1 ASP 71.A OD1 no hydrogen 3.432 N/A CYS 74.A SG THR 76.A O no hydrogen 3.405 N/A GLN 77.A NE2 THR 76.A O no hydrogen 2.281 N/A ALA 80.A N SER 112.A OG no hydrogen 2.637 N/A LYS 84.A NZ ASP 67.A OD2 no hydrogen 3.141 N/A GLN 85.A N LEU 82.A O no hydrogen 3.133 N/A SER 86.A OG ASP 83.A O no hydrogen 2.979 N/A VAL 91.A N ALA 117.A O no hydrogen 2.859 N/A CYS 92.A SG LYS 84.A O no hydrogen 3.920 N/A LYS 93.A N THR 115.A O no hydrogen 2.914 N/A ARG 94.A NH1 GLN 85.A OE1 no hydrogen 3.566 N/A ARG 94.A NH2 ALA 80.A O no hydrogen 2.352 N/A THR 95.A N LEU 113.A O no hydrogen 2.877 N/A THR 95.A OG1 LEU 113.A O no hydrogen 3.567 N/A VAL 97.A N GLY 111.A O no hydrogen 3.363 N/A TRP 101.A N CYS 105.A O no hydrogen 2.948 N/A ASN 103.A ND2 ASP 98.A O no hydrogen 3.534 N/A LYS 110.A NZ ASP 98.A OD1 no hydrogen 2.680 N/A GLY 111.A N VAL 97.A O no hydrogen 2.610 N/A LEU 113.A N THR 95.A O no hydrogen 2.883 N/A VAL 114.A N ASP 71.A O no hydrogen 2.875 N/A THR 115.A N LYS 93.A O no hydrogen 2.951 N/A THR 115.A OG1 GLN 244.A OE1 no hydrogen 3.506 N/A CYS 116.A N ALA 69.A O no hydrogen 2.913 N/A ALA 117.A N VAL 91.A O no hydrogen 2.914 N/A PHE 119.A N GLN 89.A O no hydrogen 3.056 N/A ALA 120.A N SER 64.A O no hydrogen 2.952 N/A CYS 121.A SG GLU 62.A O no hydrogen 3.838 N/A CYS 121.A SG SER 122.A O no hydrogen 3.961 N/A SER 122.A N GLU 62.A O no hydrogen 3.045 N/A THR 126.A N THR 196.A O no hydrogen 3.002 N/A THR 126.A OG1 THR 196.A OG1 no hydrogen 2.987 N/A LYS 128.A N TYR 194.A O no hydrogen 2.838 N/A SER 129.A N ALA 54.A O no hydrogen 2.916 N/A SER 129.A OG ALA 54.A O no hydrogen 3.410 N/A ASN 134.A ND2 GLN 131.A OE1 no hydrogen 3.680 N/A GLU 136.A N THR 49.A O no hydrogen 2.889 N/A TYR 137.A N ILE 160.A O no hydrogen 2.884 N/A TYR 137.A OH PRO 183.A O no hydrogen 3.112 N/A ARG 138.A N THR 47.A O no hydrogen 3.170 N/A ARG 138.A NE THR 47.A OG1 no hydrogen 3.393 N/A ILE 139.A N VAL 158.A O no hydrogen 2.881 N/A MET 140.A N GLU 44.A O no hydrogen 2.915 N/A LEU 141.A N ALA 156.A O no hydrogen 2.963 N/A SER 142.A N ASP 42.A O no hydrogen 2.900 N/A VAL 143.A N ASN 154.A O no hydrogen 3.069 N/A HIS 144.A N THR 40.A O no hydrogen 3.127 N/A HIS 144.A NE2 ASP 42.A OD1 no hydrogen 2.887 N/A HIS 144.A NE2 ASP 42.A OD2 no hydrogen 3.190 N/A ASN 154.A N ASP 152.A OD1 no hydrogen 3.408 N/A ARG 155.A N ASP 152.A OD1 no hydrogen 3.313 N/A ALA 156.A N LEU 141.A O no hydrogen 2.896 N/A LYS 157.A NZ GLU 159.A OE2 no hydrogen 2.820 N/A VAL 158.A N ILE 139.A O no hydrogen 2.863 N/A ILE 160.A N TYR 137.A O no hydrogen 2.913 N/A THR 161.A OG1 SER 164.A OG no hydrogen 3.376 N/A SER 164.A N THR 161.A O no hydrogen 2.797 N/A SER 164.A OG THR 161.A OG1 no hydrogen 3.376 N/A SER 164.A OG SER 164.A O no hydrogen 2.415 N/A ALA 167.A N LEU 179.A O no hydrogen 2.926 N/A ALA 169.A N LEU 177.A O no hydrogen 2.925 N/A LEU 171.A N GLY 175.A O no hydrogen 2.917 N/A PHE 174.A N LEU 171.A O no hydrogen 2.845 N/A SER 176.A N LYS 288.A O no hydrogen 3.113 N/A SER 176.A OG GLU 168.A OE1 no hydrogen 3.220 N/A LEU 177.A N ALA 169.A O no hydrogen 2.902 N/A GLY 178.A N LYS 285.A O no hydrogen 3.140 N/A LEU 179.A N ALA 167.A O no hydrogen 2.906 N/A ASP 180.A N ARG 283.A O no hydrogen 2.865 N/A CYS 181.A N PRO 165.A O no hydrogen 3.165 N/A CYS 181.A SG LYS 281.A O no hydrogen 3.095 N/A GLU 182.A N LYS 281.A O no hydrogen 3.061 N/A THR 185.A OG1 THR 185.A O no hydrogen 2.431 N/A SER 190.A N ASP 188.A O no hydrogen 2.714 N/A TYR 193.A N VAL 204.A O no hydrogen 2.798 N/A TYR 194.A N LYS 128.A O no hydrogen 2.866 N/A LEU 195.A N TRP 202.A O no hydrogen 2.910 N/A THR 196.A N THR 126.A O no hydrogen 2.934 N/A THR 196.A OG1 THR 126.A O no hydrogen 3.362 N/A MET 197.A N LYS 200.A O no hydrogen 3.362 N/A ASN 198.A ND2 GLU 253.A OE1 no hydrogen 3.196 N/A TRP 202.A N LEU 195.A O no hydrogen 2.846 N/A LEU 203.A N LEU 264.A O no hydrogen 2.607 N/A VAL 204.A N TYR 193.A O no hydrogen 2.891 N/A LYS 206.A N ASP 191.A O no hydrogen 2.515 N/A TRP 208.A N HIS 205.A O no hydrogen 2.993 N/A LEU 214.A N ILE 212.A O no hydrogen 3.100 N/A HIS 217.A N SER 58.A O no hydrogen 2.974 N/A HIS 217.A NE2 ALA 220.A O no hydrogen 2.846 N/A ASN 228.A N TRP 216.A O no hydrogen 3.056 N/A LYS 230.A NZ THR 88.A O no hydrogen 2.739 N/A VAL 234.A N GLU 231.A O no hydrogen 3.328 N/A GLU 235.A N VAL 247.A O no hydrogen 2.837 N/A LYS 242.A N HIS 240.A O no hydrogen 2.799 N/A THR 245.A N LYS 237.A O no hydrogen 2.911 N/A THR 245.A OG1 LYS 237.A O no hydrogen 2.625 N/A VAL 247.A N GLU 235.A O no hydrogen 2.960 N/A LEU 249.A N LEU 233.A O no hydrogen 3.500 N/A SER 251.A OG GLU 62.A OE2 no hydrogen 3.014 N/A GLN 252.A N GLY 250.A O no hydrogen 2.810 N/A VAL 256.A N GLN 252.A O no hydrogen 3.152 N/A HIS 257.A ND1 GLU 253.A O no hydrogen 2.366 N/A THR 258.A N GLY 254.A O no hydrogen 3.290 N/A THR 258.A OG1 ALA 255.A O no hydrogen 3.370 N/A ALA 259.A N ALA 255.A O no hydrogen 3.129 N/A LEU 260.A N VAL 256.A O no hydrogen 2.804 N/A ALA 266.A N HIS 201.A O no hydrogen 2.841 N/A GLU 267.A N ARG 274.A O no hydrogen 3.026 N/A ASP 269.A N LYS 272.A O no hydrogen 2.891 N/A LYS 272.A N ASP 269.A O no hydrogen 2.937 N/A GLY 273.A N VAL 50.A O no hydrogen 2.896 N/A ARG 274.A N GLU 267.A O no hydrogen 2.809 N/A LEU 275.A N THR 48.A O no hydrogen 2.843 N/A LEU 280.A N LEU 25.A O no hydrogen 2.785 N/A LYS 281.A NZ GLU 182.A OE2 no hydrogen 3.376 N/A CYS 282.A N VAL 23.A O no hydrogen 2.859 N/A ARG 283.A N ASP 180.A O no hydrogen 2.532 N/A ARG 283.A NE ASP 22.A OD1 no hydrogen 2.701 N/A ARG 283.A NH1 ASP 22.A OD2 no hydrogen 3.508 N/A LEU 284.A N VAL 21.A O no hydrogen 2.732 N/A LYS 285.A N GLY 178.A O no hydrogen 2.741 N/A LYS 285.A NZ ASP 180.A OD2 no hydrogen 2.871 N/A ARG 290.A N PHE 174.A O no hydrogen 2.828 N/A LYS 292.A NZ GLU 153.A OE1 no hydrogen 3.187 N/A LYS 292.A NZ GLU 153.A OE2 no hydrogen 2.461 N/A SER 295.A OG VAL 294.A O no hydrogen 2.306 N/A TYR 296.A N GLY 293.A O no hydrogen 3.051 N/A CYS 299.A N LYS 331.A O no hydrogen 2.492 N/A CYS 299.A SG LYS 331.A O no hydrogen 3.230 N/A THR 300.A OG1 THR 300.A O no hydrogen 2.297 N/A THR 304.A N GLN 322.A O no hydrogen 2.959 N/A THR 304.A OG1 GLN 322.A O no hydrogen 3.485 N/A THR 306.A N GLU 320.A O no hydrogen 3.007 N/A THR 306.A OG1 GLU 320.A O no hydrogen 2.805 N/A ALA 310.A N THR 318.A O no hydrogen 3.123 N/A THR 312.A N THR 316.A O no hydrogen 3.044 N/A THR 312.A OG1 THR 316.A O no hydrogen 3.172 N/A THR 312.A OG1 THR 316.A OG1 no hydrogen 2.289 N/A THR 316.A OG1 THR 312.A OG1 no hydrogen 2.289 N/A THR 316.A OG1 GLU 368.A OE1 no hydrogen 2.793 N/A VAL 317.A N LEU 369.A O no hydrogen 2.896 N/A THR 318.A N ALA 310.A O no hydrogen 2.764 N/A THR 318.A OG1 ALA 310.A O no hydrogen 3.500 N/A VAL 319.A N LEU 367.A O no hydrogen 2.849 N/A VAL 321.A N MET 365.A O no hydrogen 2.866 N/A GLN 322.A N THR 304.A O no hydrogen 2.890 N/A GLN 322.A NE2 ASN 362.A OD1 no hydrogen 2.854 N/A TYR 323.A N SER 363.A O no hydrogen 2.867 N/A CYS 330.A N ILE 356.A O no hydrogen 3.132 N/A CYS 330.A SG SER 297.A O no hydrogen 3.185 N/A LYS 331.A N SER 297.A O no hydrogen 3.374 N/A VAL 332.A N PRO 354.A O no hydrogen 3.167 N/A GLN 335.A N VAL 379.A O no hydrogen 2.954 N/A ALA 337.A N TYR 377.A O no hydrogen 2.915 N/A GLN 341.A NE2 GLN 341.A O no hydrogen 3.388 N/A THR 342.A N ASP 339.A O no hydrogen 2.953 N/A THR 342.A N ASP 339.A OD2 no hydrogen 3.217 N/A THR 342.A OG1 ASP 339.A OD2 no hydrogen 2.613 N/A THR 342.A OG1 THR 342.A O no hydrogen 2.498 N/A VAL 346.A N MET 336.A O no hydrogen 2.898 N/A ARG 348.A N ASP 370.A O no hydrogen 2.942 N/A ARG 348.A NH1 ASP 370.A OD2 no hydrogen 2.952 N/A THR 351.A OG1 GLU 368.A O no hydrogen 3.352 N/A ILE 356.A N CYS 330.A O no hydrogen 3.077 N/A SER 359.A OG SER 359.A O no hydrogen 2.397 N/A GLU 361.A N THR 360.A OG1 no hydrogen 2.608 N/A SER 363.A N TYR 323.A O no hydrogen 3.007 N/A MET 365.A N VAL 321.A O no hydrogen 2.964 N/A MET 366.A N GLN 147.A O no hydrogen 3.345 N/A LEU 367.A N VAL 319.A O no hydrogen 2.943 N/A LEU 369.A N VAL 317.A O no hydrogen 2.912 N/A ASP 370.A N ARG 348.A O no hydrogen 2.631 N/A SER 376.A N TRP 391.A O no hydrogen 2.903 N/A SER 376.A OG ALA 337.A O no hydrogen 2.934 N/A TYR 377.A N ALA 337.A O no hydrogen 2.862 N/A ILE 378.A N HIS 389.A O no hydrogen 2.857 N/A VAL 379.A N GLN 335.A O no hydrogen 2.911 N/A ILE 380.A N ILE 387.A O no hydrogen 2.972 N/A GLY 381.A N PRO 333.A O no hydrogen 3.209 N/A ILE 387.A N ILE 380.A O no hydrogen 2.890 N/A HIS 389.A N ILE 378.A O no hydrogen 2.933 N/A TRP 391.A N SER 376.A O no hydrogen 2.880 N/A HIS 392.A ND1 ASP 375.A OD1 no hydrogen 2.242 N/A ARG 393.A NH2 PRO 371.A O no hydrogen 2.600 N/A LYS 400.A N SER 396.A O no hydrogen 3.376 N/A ALA 401.A N THR 397.A O no hydrogen 2.891 N/A PHE 402.A N ILE 398.A O no hydrogen 2.942 N/A GLU 403.A N GLY 399.A O no hydrogen 2.905 N/A ALA 404.A N LYS 400.A O no hydrogen 2.889 N/A THR 405.A N ALA 401.A O no hydrogen 2.935 N/A THR 405.A OG1 ALA 401.A O no hydrogen 3.321 N/A THR 405.A OG1 PHE 402.A O no hydrogen 2.463 N/A VAL 406.A N PHE 402.A O no hydrogen 2.947 N/A ARG 407.A N GLU 403.A O no hydrogen 2.899 N/A GLY 408.A N ALA 404.A O no hydrogen 2.910 N/A ALA 409.A N THR 405.A O no hydrogen 2.903 N/A LYS 410.A N VAL 406.A O no hydrogen 2.943 N/A ARG 411.A N ARG 407.A O no hydrogen 2.888 N/A MET 412.A N GLY 408.A O no hydrogen 2.917 N/A ALA 413.A N ALA 409.A O no hydrogen 2.897 N/A VAL 414.A N LYS 410.A O no hydrogen 2.945 N/A LEU 415.A N ARG 411.A O no hydrogen 2.902 N/A GLY 416.A N MET 412.A O no hydrogen 2.857 N/A ALA 419.A N GLY 416.A O no hydrogen 3.277 N/A TRP 420.A N ASP 417.A O no hydrogen 3.002 N/A TRP 420.A NE1 HIS 437.A ND1 no hydrogen 3.052 N/A ASP 421.A N THR 418.A O no hydrogen 2.888 N/A PHE 422.A N ALA 419.A O no hydrogen 3.225 N/A SER 424.A OG TRP 420.A O no hydrogen 3.357 N/A SER 424.A OG ASN 430.A OD1 no hydrogen 2.693 N/A VAL 425.A N GLY 423.A O no hydrogen 3.035 N/A ASN 430.A ND2 TRP 420.A O no hydrogen 2.921 N/A LEU 432.A N ALA 428.A O no hydrogen 2.873 N/A GLY 433.A N LEU 429.A O no hydrogen 2.929 N/A LYS 434.A N ASN 430.A O no hydrogen 2.919 N/A GLY 435.A N SER 431.A O no hydrogen 2.923 N/A ILE 436.A N LEU 432.A O no hydrogen 3.004 N/A HIS 437.A N GLY 433.A O no hydrogen 2.897 N/A GLN 438.A N LYS 434.A O no hydrogen 2.874 N/A ILE 439.A N GLY 435.A O no hydrogen 3.029 N/A PHE 440.A N ILE 436.A O no hydrogen 2.970 N/A GLY 441.A N HIS 437.A O no hydrogen 2.823 N/A ALA 442.A N GLN 438.A O no hydrogen 2.927 N/A ALA 443.A N ILE 439.A O no hydrogen 3.025 N/A PHE 444.A N PHE 440.A O no hydrogen 2.884 N/A LYS 445.A N GLY 441.A O no hydrogen 2.869 N/A SER 446.A N ALA 442.A O no hydrogen 2.947 N/A LEU 447.A N ALA 443.A O no hydrogen 2.944 N/A LEU 447.A N PHE 444.A O no hydrogen 3.212 N/A GLN 456.A N SER 452.A O no hydrogen 2.902 N/A ILE 457.A N TRP 453.A O no hydrogen 2.963 N/A LEU 458.A N PHE 454.A O no hydrogen 2.959 N/A ILE 459.A N SER 455.A O no hydrogen 2.989 N/A GLY 460.A N GLN 456.A O no hydrogen 2.824 N/A THR 461.A N ILE 457.A O no hydrogen 2.977 N/A THR 461.A OG1 ILE 457.A O no hydrogen 3.161 N/A LEU 462.A N LEU 458.A O no hydrogen 2.949 N/A LEU 463.A N ILE 459.A O no hydrogen 2.935 N/A MET 464.A N GLY 460.A O no hydrogen 2.873 N/A TRP 465.A N THR 461.A O no hydrogen 3.022 N/A LEU 466.A N LEU 462.A O no hydrogen 2.956 N/A GLY 467.A N LEU 463.A O no hydrogen 2.864 N/A LEU 468.A N MET 464.A O no hydrogen 2.883 N/A ASN 469.A N TRP 465.A O no hydrogen 3.026 N/A ASN 469.A N LEU 466.A O no hydrogen 3.235 N/A GLY 473.A N ASN 472.A OD1 no hydrogen 2.299 N/A MET 478.A N SER 474.A O no hydrogen 3.029 N/A CYS 479.A N ILE 475.A O no hydrogen 2.758 N/A CYS 479.A SG ILE 475.A O no hydrogen 3.789 N/A LEU 480.A N SER 476.A O no hydrogen 2.646 N/A ALA 481.A N LEU 477.A O no hydrogen 3.151 N/A LEU 482.A N MET 478.A O no hydrogen 3.231 N/A GLY 483.A N CYS 479.A O no hydrogen 3.357 N/A GLY 484.A N LEU 480.A O no hydrogen 3.352 N/A VAL 485.A N ALA 481.A O no hydrogen 2.808 N/A LEU 486.A N LEU 482.A O no hydrogen 2.669 N/A ILE 487.A N GLY 483.A O no hydrogen 2.561 N/A PHE 488.A N GLY 484.A O no hydrogen 2.981 N/A PHE 488.A N VAL 485.A O no hydrogen 2.964 N/A LEU 489.A N LEU 486.A O no hydrogen 2.945 N/A SER 490.A N LEU 486.A O no hydrogen 3.201 N/A THR 491.A OG1 ILE 487.A O no hydrogen 3.146 N/A