Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8cyl_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 4.A N SER 2.A OG no hydrogen 3.090 N/A LEU 6.A N PRO 3.A O no hydrogen 2.900 N/A LEU 7.A N ALA 4.A O no hydrogen 3.413 N/A VAL 11.A N THR 8.A O no hydrogen 2.996 N/A LEU 12.A N THR 9.A O no hydrogen 3.150 N/A THR 13.A N PRO 10.A O no hydrogen 3.399 N/A THR 13.A OG1 THR 9.A O no hydrogen 2.699 N/A VAL 15.A N PRO 10.A O no hydrogen 2.922 N/A GLY 16.A N PRO 10.A O no hydrogen 3.219 N/A ASP 18.A N GLY 23.A O no hydrogen 2.977 N/A ASN 19.A N GLN 254.A O no hydrogen 2.997 N/A ASN 19.A ND2 ARG 40.A O no hydrogen 2.900 N/A ASN 19.A ND2 SER 253.A OG no hydrogen 3.081 N/A ARG 20.A N ASP 18.A OD1 no hydrogen 2.919 N/A ARG 20.A NE ASP 102.A OD1 no hydrogen 2.782 N/A ARG 20.A NH1 THR 251.A O no hydrogen 2.953 N/A ARG 20.A NH2 THR 37.A OG1 no hydrogen 3.354 N/A ARG 20.A NH2 ASP 102.A OD1 no hydrogen 3.402 N/A ARG 20.A NH2 ASP 102.A OD2 no hydrogen 2.818 N/A TRP 21.A N ASP 18.A OD1 no hydrogen 2.674 N/A TRP 21.A NE1 THR 201.A O no hydrogen 3.009 N/A ASN 22.A N ASP 18.A O no hydrogen 3.072 N/A GLY 23.A N ASP 18.A OD2 no hydrogen 3.011 N/A GLN 24.A NE2 GLY 14.A O no hydrogen 2.829 N/A ILE 25.A N GLY 16.A O no hydrogen 3.020 N/A VAL 26.A N ALA 228.A O no hydrogen 2.802 N/A GLY 27.A N ALA 228.A O no hydrogen 3.096 N/A LEU 28.A N ILE 309.A O no hydrogen 2.908 N/A GLN 29.A N MET 226.A O no hydrogen 2.777 N/A GLN 29.A NE2 PRO 30.A O no hydrogen 2.978 N/A GLN 29.A NE2 THR 306.A O no hydrogen 2.958 N/A VAL 31.A N PRO 224.A O no hydrogen 2.877 N/A GLY 34.A N VAL 31.A O no hydrogen 2.848 N/A PHE 35.A N ALA 216.A O no hydrogen 3.281 N/A THR 37.A N TYR 297.A OH no hydrogen 2.970 N/A THR 37.A OG1 SER 36.A O no hydrogen 2.566 N/A ARG 40.A NE ARG 55.A O no hydrogen 3.029 N/A ARG 40.A NH1 ASN 19.A O no hydrogen 2.935 N/A HIS 41.A N CYS 38.A O no hydrogen 3.148 N/A HIS 41.A ND1 SER 253.A OG no hydrogen 2.767 N/A HIS 41.A NE2 ASP 295.A O no hydrogen 3.001 N/A TRP 42.A N GLN 254.A OE1 no hydrogen 3.268 N/A ASN 43.A N SER 47.A O no hydrogen 2.934 N/A LEU 44.A N VAL 294.A O no hydrogen 3.114 N/A ASN 45.A N ASN 43.A OD1 no hydrogen 2.799 N/A SER 47.A N ASN 43.A OD1 no hydrogen 2.964 N/A SER 47.A OG ASN 45.A O no hydrogen 3.376 N/A THR 48.A OG1 HIS 41.A O no hydrogen 2.780 N/A GLY 50.A N THR 48.A OG1 no hydrogen 3.072 N/A TRP 51.A N ASN 39.A OD1 no hydrogen 3.220 N/A TRP 51.A NE1 PHE 100.A O no hydrogen 2.838 N/A SER 52.A OG ASN 39.A OD1 no hydrogen 2.702 N/A SER 53.A N ASP 98.A OD1 no hydrogen 3.018 N/A SER 53.A OG ASP 98.A OD1 no hydrogen 3.431 N/A SER 53.A OG ASP 98.A OD2 no hydrogen 2.776 N/A ARG 55.A N SER 53.A O no hydrogen 2.803 N/A ILE 59.A N VAL 184.A O no hydrogen 2.635 N/A HIS 61.A N LEU 182.A O no hydrogen 3.147 N/A HIS 61.A NE2 SER 86.A OG no hydrogen 2.977 N/A ARG 62.A NE SER 127.A O no hydrogen 2.806 N/A ARG 62.A NH2 SER 127.A O no hydrogen 3.016 N/A ARG 63.A N HIS 61.A ND1 no hydrogen 3.068 N/A GLY 64.A N ALA 180.A O no hydrogen 2.884 N/A SER 65.A N TYR 81.A O no hydrogen 2.838 N/A ALA 66.A N GLN 177.A O no hydrogen 2.898 N/A SER 67.A N PHE 79.A O no hydrogen 3.038 N/A THR 74.A N ASN 72.A OD1 no hydrogen 2.928 N/A THR 74.A OG1 ASN 72.A OD1 no hydrogen 3.220 N/A ASN 75.A N VAL 172.A O no hydrogen 3.079 N/A GLN 78.A N SER 167.A OG no hydrogen 2.959 N/A GLN 78.A NE2 PHE 79.A O no hydrogen 3.011 N/A GLN 78.A NE2 THR 175.A O no hydrogen 3.030 N/A PHE 79.A N SER 67.A O no hydrogen 2.967 N/A TRP 80.A N ALA 165.A O no hydrogen 2.806 N/A TRP 80.A NE1 ALA 180.A O no hydrogen 2.884 N/A TYR 81.A N SER 65.A O no hydrogen 3.088 N/A ALA 82.A N THR 163.A O no hydrogen 2.972 N/A ALA 84.A N SER 161.A O no hydrogen 2.923 N/A GLY 85.A N VAL 95.A O no hydrogen 2.848 N/A SER 86.A N ASN 83.A O no hydrogen 3.114 N/A SER 86.A OG HIS 61.A NE2 no hydrogen 2.977 N/A SER 86.A OG ASN 83.A O no hydrogen 2.648 N/A ALA 87.A N GLN 94.A O no hydrogen 3.185 N/A ASN 90.A N ALA 87.A O no hydrogen 3.014 N/A ASN 90.A ND2 TRP 51.A O no hydrogen 2.877 N/A ASN 90.A ND2 ALA 96.A O no hydrogen 2.957 N/A ILE 92.A N ASN 90.A OD1 no hydrogen 3.002 N/A GLN 94.A NE2 ASN 90.A O no hydrogen 2.903 N/A VAL 95.A N SER 93.A OG no hydrogen 3.192 N/A GLY 99.A N SER 52.A OG no hydrogen 2.909 N/A PHE 100.A N PRO 97.A O no hydrogen 2.938 N/A SER 104.A N ARG 206.A O no hydrogen 2.912 N/A SER 104.A OG ARG 206.A O no hydrogen 3.545 N/A PHE 105.A N PHE 144.A O no hydrogen 2.844 N/A VAL 106.A N GLU 141.A OE2 no hydrogen 2.758 N/A ALA 116.A N SER 191.A O no hydrogen 2.833 N/A GLY 117.A N SER 191.A OG no hydrogen 2.871 N/A VAL 119.A N VAL 189.A O no hydrogen 2.904 N/A GLY 120.A N TYR 140.A O no hydrogen 2.918 N/A GLY 122.A N GLN 138.A O no hydrogen 3.019 N/A ALA 123.A N PHE 183.A O no hydrogen 2.918 N/A ILE 124.A N THR 136.A OG1 no hydrogen 2.924 N/A TRP 125.A N GLY 181.A O no hydrogen 2.917 N/A ASN 126.A N ALA 131.A O no hydrogen 2.855 N/A SER 127.A OG ARG 62.A O no hydrogen 2.745 N/A ASN 128.A N ASN 126.A OD1 no hydrogen 2.936 N/A SER 129.A N ASN 126.A O no hydrogen 3.193 N/A SER 129.A N ASN 126.A OD1 no hydrogen 3.107 N/A GLY 130.A N ASN 126.A O no hydrogen 2.769 N/A ALA 131.A N SER 129.A OG no hydrogen 3.015 N/A ASN 133.A N ILE 124.A O no hydrogen 2.715 N/A THR 135.A N ASN 133.A OD1 no hydrogen 3.460 N/A THR 135.A OG1 ASN 133.A OD1 no hydrogen 2.984 N/A THR 135.A OG1 THR 173.A O no hydrogen 2.881 N/A THR 136.A N ASN 133.A O no hydrogen 2.967 N/A THR 136.A OG1 ILE 124.A O no hydrogen 3.471 N/A THR 136.A OG1 ASN 133.A O no hydrogen 2.730 N/A GLN 138.A N GLY 122.A O no hydrogen 3.041 N/A GLN 138.A NE2 ALA 170.A O no hydrogen 3.030 N/A ALA 139.A N GLN 138.A OE1 no hydrogen 2.791 N/A TYR 140.A N GLY 120.A O no hydrogen 2.788 N/A TYR 140.A OH THR 136.A O no hydrogen 2.641 N/A GLU 141.A N LYS 166.A O no hydrogen 2.861 N/A LEU 142.A N TRP 118.A O no hydrogen 2.994 N/A GLY 143.A N VAL 164.A O no hydrogen 3.169 N/A PHE 144.A N MET 103.A O no hydrogen 2.955 N/A ALA 145.A N GLN 162.A O no hydrogen 2.935 N/A THR 146.A N GLN 153.A O no hydrogen 2.920 N/A ALA 148.A N GLN 162.A OE1 no hydrogen 2.890 N/A ASN 151.A N GLY 147.A O no hydrogen 2.919 N/A GLN 153.A N THR 146.A O no hydrogen 2.944 N/A THR 158.A N THR 209.A O no hydrogen 3.112 N/A SER 159.A N ASN 157.A OD1 no hydrogen 2.976 N/A SER 161.A N THR 158.A O no hydrogen 3.098 N/A SER 161.A OG THR 158.A O no hydrogen 2.708 N/A GLN 162.A N ALA 145.A O no hydrogen 2.733 N/A GLN 162.A NE2 ALA 148.A O no hydrogen 3.646 N/A THR 163.A N ALA 82.A O no hydrogen 2.806 N/A THR 163.A OG1 ALA 82.A O no hydrogen 3.262 N/A VAL 164.A N GLY 143.A O no hydrogen 2.974 N/A ALA 165.A N TRP 80.A O no hydrogen 2.729 N/A LYS 166.A N GLU 141.A O no hydrogen 2.967 N/A LYS 166.A NZ PHE 108.A O no hydrogen 2.840 N/A SER 167.A N GLN 78.A O no hydrogen 2.825 N/A SER 167.A OG TYR 169.A O no hydrogen 2.721 N/A ILE 168.A N ALA 139.A O no hydrogen 2.971 N/A VAL 171.A N VAL 76.A O no hydrogen 2.891 N/A THR 173.A N THR 135.A O no hydrogen 3.084 N/A GLY 174.A N ALA 73.A O no hydrogen 2.861 N/A THR 175.A N GLN 78.A OE1 no hydrogen 2.789 N/A ALA 180.A N GLY 64.A O no hydrogen 2.903 N/A GLY 181.A N TRP 125.A O no hydrogen 2.865 N/A LEU 182.A N HIS 61.A O no hydrogen 2.845 N/A PHE 183.A N ALA 123.A O no hydrogen 3.015 N/A VAL 184.A N ILE 59.A O no hydrogen 2.986 N/A MET 185.A N PHE 121.A O no hydrogen 3.021 N/A ALA 186.A N ALA 57.A O no hydrogen 3.114 N/A VAL 189.A N VAL 119.A O no hydrogen 2.827 N/A ILE 190.A N ARG 232.A O no hydrogen 2.933 N/A SER 191.A N GLY 117.A O no hydrogen 2.944 N/A SER 191.A OG PRO 114.A O no hydrogen 2.564 N/A THR 192.A N THR 234.A OG1 no hydrogen 3.126 N/A THR 192.A OG1 SER 194.A O no hydrogen 2.842 N/A ASN 196.A N SER 194.A OG no hydrogen 3.224 N/A ASN 196.A ND2 SER 194.A OG no hydrogen 3.256 N/A ALA 197.A N ASN 245.A O no hydrogen 3.019 N/A ILE 198.A N GLN 248.A OE1 no hydrogen 2.734 N/A THR 201.A N TYR 249.A O no hydrogen 3.097 N/A THR 201.A OG1 THR 199.A O no hydrogen 2.948 N/A GLN 203.A NE2 TYR 200.A O no hydrogen 2.869 N/A ARG 206.A N GLN 203.A O no hydrogen 2.934 N/A ARG 206.A NE SER 104.A O no hydrogen 3.229 N/A ARG 206.A NE SER 104.A OG no hydrogen 2.919 N/A ARG 206.A NH1 ALA 116.A O no hydrogen 2.745 N/A ARG 206.A NH2 SER 104.A O no hydrogen 2.814 N/A ARG 206.A NH2 ALA 116.A O no hydrogen 2.918 N/A ILE 207.A N PRO 204.A O no hydrogen 3.310 N/A VAL 208.A N ASP 102.A O no hydrogen 2.802 N/A THR 209.A N THR 156.A O no hydrogen 3.081 N/A THR 210.A OG1 TYR 49.A O no hydrogen 2.725 N/A THR 210.A OG1 THR 213.A OG1 no hydrogen 3.037 N/A THR 213.A N THR 210.A O no hydrogen 3.073 N/A THR 213.A OG1 THR 210.A O no hydrogen 2.816 N/A THR 213.A OG1 THR 210.A OG1 no hydrogen 3.037 N/A ALA 216.A N PHE 35.A O no hydrogen 2.755 N/A VAL 219.A N ASN 222.A O no hydrogen 2.901 N/A ASN 222.A N VAL 219.A O no hydrogen 2.847 N/A ASN 222.A ND2 SER 325.A O no hydrogen 2.889 N/A ASN 222.A ND2 SER 327.A O no hydrogen 2.852 N/A THR 223.A N ALA 300.A O no hydrogen 2.787 N/A THR 223.A OG1 GLY 303.A O no hydrogen 2.595 N/A ILE 225.A N PHE 298.A O no hydrogen 2.857 N/A MET 226.A N GLN 29.A O no hydrogen 2.898 N/A PHE 227.A N GLY 252.A O no hydrogen 2.729 N/A ALA 228.A N GLY 27.A O no hydrogen 2.787 N/A SER 229.A N.A GLY 250.A O no hydrogen 2.869 N/A SER 229.A N.B GLY 250.A O no hydrogen 2.872 N/A SER 229.A OG.A ASP 18.A OD2 no hydrogen 2.796 N/A SER 229.A OG.A GLY 250.A O no hydrogen 3.460 N/A SER 229.A OG.B ASP 18.A OD2 no hydrogen 2.844 N/A SER 229.A OG.B GLY 23.A O no hydrogen 2.815 N/A VAL 231.A N GLN 248.A O no hydrogen 3.094 N/A ARG 232.A NH1 VAL 237.A O no hydrogen 2.971 N/A ARG 233.A NE ALA 195.A O no hydrogen 2.868 N/A ARG 233.A NH1 GLY 246.A O no hydrogen 3.179 N/A ARG 233.A NH2 ALA 195.A O no hydrogen 2.968 N/A ARG 233.A NH2 GLY 246.A O no hydrogen 2.971 N/A THR 234.A N ILE 190.A O no hydrogen 2.957 N/A THR 234.A OG1 THR 192.A O no hydrogen 3.502 N/A GLY 235.A N THR 192.A OG1 no hydrogen 3.132 N/A ASP 236.A N ARG 233.A O no hydrogen 3.425 N/A ASN 238.A N ASP 236.A OD1 no hydrogen 3.160 N/A ALA 239.A N ASP 236.A O no hydrogen 3.330 N/A GLY 242.A N THR 247.A OG1 no hydrogen 2.839 N/A SER 243.A N THR 240.A O no hydrogen 3.257 N/A ASN 245.A N SER 243.A OG no hydrogen 2.966 N/A ASN 245.A ND2 ASP 236.A OD2 no hydrogen 2.812 N/A GLY 246.A N SER 243.A O no hydrogen 2.833 N/A GLN 248.A NE2 ILE 198.A O no hydrogen 3.338 N/A GLN 248.A NE2 THR 199.A O no hydrogen 3.093 N/A GLN 248.A NE2 TYR 249.A O no hydrogen 3.174 N/A GLY 250.A N SER 229.A O.A no hydrogen 2.799 N/A GLY 250.A N SER 229.A O.B no hydrogen 2.918 N/A THR 251.A N THR 201.A O no hydrogen 2.975 N/A THR 251.A OG1 PRO 202.A O no hydrogen 3.538 N/A GLY 252.A N PHE 227.A O no hydrogen 2.894 N/A SER 253.A OG HIS 41.A ND1 no hydrogen 2.767 N/A GLN 254.A N ASN 19.A OD1 no hydrogen 3.197 N/A GLN 254.A NE2 TRP 42.A O no hydrogen 2.855 N/A GLN 254.A NE2 GLY 296.A O no hydrogen 2.774 N/A LEU 256.A N ASN 17.A O no hydrogen 2.759 N/A VAL 258.A N PRO 255.A O no hydrogen 2.870 N/A THR 259.A N PRO 255.A O no hydrogen 3.090 N/A THR 259.A OG1 GLN 254.A OE1 no hydrogen 2.837 N/A THR 259.A OG1 PRO 255.A O no hydrogen 3.360 N/A ILE 260.A N LEU 256.A O no hydrogen 2.857 N/A GLY 261.A N PRO 257.A O no hydrogen 3.089 N/A LEU 262.A N VAL 258.A O no hydrogen 2.866 N/A SER 263.A N THR 259.A O no hydrogen 3.010 N/A SER 263.A N ILE 260.A O no hydrogen 2.977 N/A SER 263.A OG ILE 260.A O no hydrogen 2.655 N/A LEU 264.A N GLY 261.A O no hydrogen 3.117 N/A ASN 265.A N GLY 261.A O no hydrogen 3.320 N/A TYR 267.A N LEU 44.A O no hydrogen 3.008 N/A SER 268.A N ASN 266.A OD1 no hydrogen 2.744 N/A SER 268.A OG ASN 266.A OD1 no hydrogen 2.543 N/A ALA 270.A N TYR 267.A O no hydrogen 3.041 N/A MET 272.A N GLN 275.A OE1 no hydrogen 2.688 N/A GLN 275.A N MET 272.A O no hydrogen 2.986 N/A PHE 276.A N ARG 323.A O no hydrogen 2.809 N/A PHE 277.A N LEU 292.A O no hydrogen 2.923 N/A VAL 278.A N GLY 321.A O no hydrogen 2.946 N/A TRP 279.A N ILE 290.A O no hydrogen 2.887 N/A TRP 279.A NE1 ALA 4.A O no hydrogen 2.971 N/A GLN 280.A N ARG 318.A O no hydrogen 2.763 N/A GLN 280.A NE2 THR 282.A OG1 no hydrogen 3.104 N/A LEU 281.A N MET 288.A O no hydrogen 2.746 N/A THR 282.A N ASP 316.A O no hydrogen 2.943 N/A PHE 283.A N GLY 286.A O no hydrogen 2.719 N/A PHE 287.A N ASN 332.A O no hydrogen 3.027 N/A MET 288.A N LEU 281.A O no hydrogen 2.968 N/A GLU 289.A N VAL 330.A O no hydrogen 2.882 N/A ILE 290.A N TRP 279.A O no hydrogen 2.919 N/A GLY 291.A N TYR 299.A O no hydrogen 3.090 N/A LEU 292.A N PHE 277.A O no hydrogen 2.821 N/A SER 293.A N TYR 297.A O no hydrogen 2.933 N/A SER 293.A OG TYR 297.A O no hydrogen 3.422 N/A GLY 296.A N SER 293.A O no hydrogen 2.937 N/A TYR 297.A N SER 293.A OG no hydrogen 3.392 N/A TYR 297.A OH PRO 214.A O no hydrogen 2.611 N/A TYR 299.A N GLY 291.A O no hydrogen 2.830 N/A TYR 299.A OH ALA 217.A O no hydrogen 2.966 N/A ALA 300.A N THR 223.A O no hydrogen 2.968 N/A GLY 303.A N LYS 221.A O no hydrogen 2.873 N/A SER 305.A N THR 302.A O no hydrogen 3.163 N/A THR 307.A N SER 305.A OG no hydrogen 3.151 N/A ILE 309.A N LEU 28.A O no hydrogen 2.800 N/A LEU 311.A N VAL 26.A O no hydrogen 2.995 N/A THR 312.A N ASP 310.A OD1 no hydrogen 2.809 N/A THR 312.A OG1 ASP 310.A OD1 no hydrogen 2.662 N/A THR 312.A OG1 ASP 310.A OD2 no hydrogen 3.376 N/A LEU 314.A N LEU 311.A O no hydrogen 3.074 N/A ILE 315.A N THR 282.A O no hydrogen 2.852 N/A ASP 316.A N THR 282.A O no hydrogen 3.269 N/A VAL 317.A N THR 9.A OG1 no hydrogen 2.941 N/A ARG 318.A N GLN 280.A O no hydrogen 2.979 N/A VAL 320.A N VAL 278.A O no hydrogen 2.844 N/A GLY 321.A N VAL 278.A O no hydrogen 3.138 N/A ARG 323.A N PHE 276.A O no hydrogen 2.817 N/A ARG 323.A NH1.A PRO 322.A O no hydrogen 2.820 N/A ARG 323.A NH1.B GLU 289.A OE2 no hydrogen 3.068 N/A SER 325.A N GLY 274.A O no hydrogen 2.677 N/A SER 325.A OG GLY 274.A O no hydrogen 2.667 N/A SER 327.A N PRO 324.A O no hydrogen 3.189 N/A LEU 329.A N ASN 222.A OD1 no hydrogen 2.785 N/A VAL 330.A N GLU 289.A OE1 no hydrogen 2.965 N/A ASN 332.A N PHE 287.A O no hydrogen 2.820 N/A