Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8czt_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 5.A N SER 3.A OG no hydrogen 3.179 N/A VAL 6.A N GLN 298.A OE1 no hydrogen 2.928 N/A LYS 7.A NZ GLU 289.A OE1 no hydrogen 2.655 N/A HIS 10.A N SER 115.A OG no hydrogen 2.872 N/A SER 12.A OG GLU 16.A OE2 no hydrogen 2.461 N/A GLU 16.A N SER 12.A O no hydrogen 2.839 N/A ALA 17.A N GLY 13.A O no hydrogen 3.424 N/A CYS 18.A N VAL 15.A O no hydrogen 2.990 N/A CYS 18.A SG ASP 14.A O no hydrogen 3.686 N/A MET 19.A N GLU 16.A O no hydrogen 3.329 N/A VAL 20.A N GLY 31.A O no hydrogen 2.968 N/A GLN 21.A N GLN 71.A O no hydrogen 2.616 N/A VAL 22.A N LEU 29.A O no hydrogen 2.821 N/A THR 23.A N SER 69.A O no hydrogen 3.021 N/A THR 23.A OG1 MET 27.A O no hydrogen 3.148 N/A CYS 24.A SG SER 67.A O no hydrogen 3.712 N/A GLY 25.A N THR 23.A OG1 no hydrogen 3.154 N/A SER 26.A OG CYS 46.A O no hydrogen 3.178 N/A LEU 29.A N VAL 22.A O no hydrogen 2.988 N/A ASN 30.A N CYS 147.A O no hydrogen 2.993 N/A ASN 30.A ND2 CYS 119.A O no hydrogen 3.093 N/A ASN 30.A ND2 GLY 145.A O no hydrogen 3.161 N/A ASN 30.A ND2 CYS 147.A O no hydrogen 2.846 N/A GLY 31.A N VAL 20.A O no hydrogen 2.947 N/A LEU 32.A N TRP 39.A O no hydrogen 2.803 N/A TRP 33.A N CYS 18.A O no hydrogen 2.660 N/A LEU 34.A N THR 37.A O no hydrogen 2.873 N/A ASP 35.A N THR 100.A OG1 no hydrogen 3.055 N/A ASN 36.A ND2 VAL 93.A O no hydrogen 3.490 N/A THR 37.A N LEU 34.A O no hydrogen 2.925 N/A VAL 38.A N LEU 91.A O no hydrogen 2.711 N/A TRP 39.A N LEU 32.A O no hydrogen 2.949 N/A CYS 40.A N LEU 89.A O no hydrogen 3.356 N/A CYS 40.A SG PRO 41.A O no hydrogen 3.580 N/A ARG 42.A N THR 87.A O no hydrogen 3.226 N/A ARG 42.A NE ASP 189.A OD2 no hydrogen 2.764 N/A ARG 42.A NH2 ASP 189.A OD1 no hydrogen 3.033 N/A ARG 42.A NH2 ASP 189.A OD2 no hydrogen 3.552 N/A VAL 44.A N PRO 41.A O no hydrogen 3.472 N/A MET 45.A N ARG 42.A O no hydrogen 3.116 N/A CYS 46.A N HIS 43.A O no hydrogen 3.109 N/A CYS 46.A SG PRO 47.A O no hydrogen 3.752 N/A CYS 46.A SG GLN 50.A O no hydrogen 2.992 N/A GLN 50.A N PRO 47.A O no hydrogen 3.028 N/A SER 52.A OG GLN 191.A O no hydrogen 3.168 N/A TYR 56.A OH ASP 189.A O no hydrogen 2.945 N/A ALA 58.A N ASN 55.A OD1 no hydrogen 2.922 N/A LEU 59.A N ASN 55.A O no hydrogen 2.867 N/A LEU 60.A N TYR 56.A O no hydrogen 2.743 N/A ILE 61.A N ASP 57.A O no hydrogen 3.134 N/A SER 62.A N ALA 58.A O no hydrogen 3.041 N/A SER 62.A OG LEU 59.A O no hydrogen 2.595 N/A MET 63.A N LEU 60.A O no hydrogen 2.903 N/A THR 64.A N SER 67.A OG no hydrogen 3.012 N/A THR 64.A OG1 SER 67.A OG no hydrogen 3.214 N/A ASN 65.A ND2 VAL 80.A O no hydrogen 2.955 N/A SER 67.A N THR 64.A O no hydrogen 3.184 N/A SER 67.A OG THR 64.A OG1 no hydrogen 3.214 N/A PHE 68.A N ASN 65.A O no hydrogen 3.245 N/A SER 69.A N THR 23.A O no hydrogen 2.966 N/A SER 69.A OG GLN 71.A OE1 no hydrogen 3.310 N/A GLN 71.A N GLN 21.A O no hydrogen 2.813 N/A LYS 72.A N ALA 75.A O no hydrogen 3.019 N/A HIS 73.A NE2 GLN 21.A OE1 no hydrogen 2.741 N/A LEU 77.A N VAL 70.A O no hydrogen 3.015 N/A VAL 80.A N THR 92.A O no hydrogen 2.641 N/A GLY 81.A N THR 92.A O no hydrogen 3.121 N/A HIS 82.A ND1 ASN 65.A OD1 no hydrogen 2.821 N/A ALA 83.A N LYS 90.A O no hydrogen 3.045 N/A GLN 85.A N LEU 88.A O no hydrogen 2.878 N/A GLN 85.A NE2 ASP 180.A O no hydrogen 3.534 N/A THR 87.A N GLY 181.A O no hydrogen 2.813 N/A THR 87.A OG1 SER 177.A OG no hydrogen 2.559 N/A THR 87.A OG1 GLY 181.A O no hydrogen 2.621 N/A LEU 88.A N GLN 85.A O no hydrogen 3.134 N/A LEU 89.A N CYS 40.A O no hydrogen 2.778 N/A LYS 90.A N ALA 83.A O no hydrogen 2.698 N/A LEU 91.A N VAL 38.A O no hydrogen 2.882 N/A THR 92.A N GLY 81.A O no hydrogen 2.617 N/A VAL 93.A N ASN 36.A O no hydrogen 2.900 N/A ASP 94.A N ARG 78.A O no hydrogen 2.995 N/A ASN 97.A N ASP 35.A O no hydrogen 3.021 N/A ASN 97.A ND2 ALA 17.A O no hydrogen 3.242 N/A ASN 97.A ND2 TRP 33.A O no hydrogen 2.925 N/A SER 99.A N ASN 97.A OD1 no hydrogen 2.941 N/A THR 100.A N ASN 97.A O no hydrogen 3.176 N/A THR 100.A OG1 ASN 97.A O no hydrogen 2.591 N/A TYR 103.A OH ASP 35.A OD2 no hydrogen 2.989 N/A THR 104.A N ILE 159.A O no hydrogen 2.897 N/A THR 104.A OG1 THR 106.A OG1 no hydrogen 3.357 N/A THR 104.A OG1 ASN 160.A OD1 no hydrogen 2.765 N/A THR 106.A N PHE 161.A O no hydrogen 2.975 N/A THR 106.A OG1 THR 104.A OG1 no hydrogen 3.357 N/A VAL 108.A N TYR 184.A OH no hydrogen 3.030 N/A GLY 111.A N MET 132.A O no hydrogen 2.750 N/A ALA 112.A N LYS 109.A O no hydrogen 3.110 N/A PHE 114.A N VAL 130.A O no hydrogen 2.856 N/A SER 115.A N TYR 152.A O no hydrogen 2.904 N/A VAL 116.A N PHE 128.A O no hydrogen 2.687 N/A LEU 117.A N VAL 150.A O no hydrogen 3.007 N/A ALA 118.A N GLY 126.A O no hydrogen 2.727 N/A CYS 119.A N SER 149.A OG no hydrogen 2.834 N/A CYS 119.A SG LEU 117.A O no hydrogen 3.565 N/A TYR 120.A N ARG 123.A O no hydrogen 3.058 N/A GLY 122.A N ASN 30.A OD1 no hydrogen 2.664 N/A ARG 123.A N TYR 120.A O no hydrogen 2.946 N/A THR 125.A N ALA 118.A O no hydrogen 2.790 N/A THR 125.A OG1 ALA 118.A O no hydrogen 3.004 N/A GLY 126.A N ALA 118.A O no hydrogen 3.376 N/A THR 127.A OG1 VAL 116.A O no hydrogen 2.774 N/A PHE 128.A N VAL 116.A O no hydrogen 3.089 N/A THR 129.A OG1 PHE 114.A O no hydrogen 3.176 N/A VAL 130.A N PHE 114.A O no hydrogen 2.983 N/A MET 132.A N ALA 112.A O no hydrogen 3.083 N/A ARG 133.A N THR 137.A O no hydrogen 2.904 N/A ARG 133.A NE ASP 199.A OD1 no hydrogen 3.354 N/A ARG 133.A NE ASP 199.A OD2 no hydrogen 3.236 N/A ARG 133.A NH1 ASP 288.A OD1 no hydrogen 3.320 N/A ARG 133.A NH1 ASP 288.A OD2 no hydrogen 3.496 N/A ARG 133.A NH2 ASP 288.A OD2 no hydrogen 2.886 N/A ASN 135.A ND2 LEU 197.A O no hydrogen 3.106 N/A TYR 136.A N ARG 133.A O no hydrogen 2.761 N/A THR 137.A N ASN 135.A OD1 no hydrogen 3.294 N/A THR 137.A OG1 ASN 135.A OD1 no hydrogen 2.793 N/A ILE 138.A N HIS 174.A O no hydrogen 2.701 N/A LEU 143.A N TYR 120.A OH no hydrogen 3.024 N/A SER 146.A N LEU 143.A O no hydrogen 3.137 N/A SER 146.A OG LEU 143.A O no hydrogen 2.689 N/A CYS 147.A SG GLN 166.A O no hydrogen 3.021 N/A GLY 148.A N HIS 165.A O no hydrogen 3.239 N/A SER 149.A N SER 146.A O no hydrogen 3.068 N/A SER 149.A OG SER 146.A O no hydrogen 2.709 N/A GLY 151.A N TYR 163.A O no hydrogen 2.645 N/A TYR 152.A N SER 115.A O no hydrogen 2.819 N/A THR 153.A N ASN 160.A O no hydrogen 2.960 N/A GLU 155.A N VAL 158.A O no hydrogen 2.950 N/A VAL 158.A N GLU 155.A O no hydrogen 3.096 N/A ILE 159.A N ALA 102.A O no hydrogen 2.842 N/A ASN 160.A N THR 153.A O no hydrogen 2.691 N/A PHE 161.A N THR 104.A O no hydrogen 2.889 N/A CYS 162.A N GLY 151.A O no hydrogen 2.825 N/A TYR 163.A N GLY 151.A O no hydrogen 3.116 N/A TYR 163.A OH HIS 165.A ND1 no hydrogen 2.985 N/A MET 164.A N SER 177.A O no hydrogen 2.800 N/A HIS 165.A N SER 149.A O no hydrogen 2.861 N/A HIS 165.A ND1 TYR 163.A OH no hydrogen 2.985 N/A GLN 166.A N THR 175.A O no hydrogen 3.300 N/A GLN 166.A NE2 THR 87.A O no hydrogen 2.973 N/A GLN 166.A NE2 SER 177.A OG no hydrogen 2.836 N/A MET 167.A N THR 175.A O no hydrogen 3.314 N/A LEU 169.A N THR 173.A O no hydrogen 2.717 N/A GLY 172.A N LEU 169.A O no hydrogen 3.124 N/A THR 173.A N ASN 171.A OD1 no hydrogen 3.114 N/A THR 173.A OG1 ASN 171.A OD1 no hydrogen 2.821 N/A HIS 174.A N ILE 138.A O no hydrogen 2.838 N/A THR 175.A N MET 167.A O no hydrogen 3.267 N/A THR 175.A OG1 TYR 136.A O no hydrogen 2.949 N/A SER 177.A N MET 164.A O no hydrogen 2.862 N/A SER 177.A OG THR 87.A OG1 no hydrogen 2.559 N/A ALA 178.A N THR 182.A O no hydrogen 2.876 N/A GLY 181.A N ALA 178.A O no hydrogen 3.017 N/A THR 182.A N ASP 180.A OD1 no hydrogen 3.134 N/A THR 182.A OG1 ASP 180.A OD1 no hydrogen 3.041 N/A TYR 184.A N GLY 176.A O no hydrogen 3.066 N/A TYR 184.A OH CYS 162.A O no hydrogen 2.502 N/A MET 188.A N GLN 194.A OE1 no hydrogen 2.959 N/A GLN 191.A N LEU 51.A O no hydrogen 2.926 N/A VAL 192.A N LYS 190.A O no hydrogen 2.737 N/A GLN 194.A NE2 MET 188.A O no hydrogen 2.640 N/A GLN 194.A NE2 LYS 190.A O no hydrogen 3.075 N/A THR 198.A OG1 ASP 199.A O no hydrogen 3.451 N/A LYS 200.A N ASP 199.A OD1 no hydrogen 2.839 N/A TYR 201.A N GLN 240.A O no hydrogen 3.232 N/A CYS 202.A N ASP 288.A OD2 no hydrogen 2.985 N/A SER 203.A N THR 242.A OG1 no hydrogen 2.695 N/A SER 203.A OG THR 242.A O no hydrogen 2.516 N/A SER 203.A OG THR 242.A OG1 no hydrogen 3.408 N/A ASN 205.A ND2 GLY 111.A O no hydrogen 2.875 N/A ASN 205.A ND2 ASP 288.A O no hydrogen 2.979 N/A VAL 206.A N CYS 202.A O no hydrogen 2.938 N/A VAL 207.A N SER 203.A O no hydrogen 2.913 N/A ALA 208.A N VAL 204.A O no hydrogen 3.036 N/A TRP 209.A N ASN 205.A O no hydrogen 3.038 N/A LEU 210.A N VAL 206.A O no hydrogen 3.011 N/A TYR 211.A N VAL 207.A O no hydrogen 2.976 N/A TYR 211.A OH VAL 259.A O no hydrogen 2.536 N/A ALA 212.A N ALA 208.A O no hydrogen 2.979 N/A ALA 213.A N TRP 209.A O no hydrogen 3.072 N/A ILE 214.A N LEU 210.A O no hydrogen 3.168 N/A LEU 215.A N TYR 211.A O no hydrogen 2.944 N/A ASN 216.A N ALA 213.A O no hydrogen 2.929 N/A ASN 216.A ND2 SER 3.A O no hydrogen 3.223 N/A ASN 216.A ND2 ALA 212.A O no hydrogen 2.589 N/A GLY 217.A N ILE 214.A O no hydrogen 2.925 N/A CYS 218.A N ALA 213.A O no hydrogen 2.777 N/A TRP 220.A NE1 GLN 279.A O no hydrogen 3.009 N/A VAL 222.A N ALA 219.A O no hydrogen 3.022 N/A THR 227.A N GLU 262.A O no hydrogen 3.066 N/A THR 227.A OG1 GLN 269.A OE1 no hydrogen 2.481 N/A SER 228.A OG SER 231.A OG no hydrogen 2.660 N/A SER 231.A N SER 228.A OG no hydrogen 3.018 N/A SER 231.A OG SER 228.A OG no hydrogen 2.660 N/A PHE 232.A N SER 228.A O no hydrogen 2.871 N/A ASN 233.A N VAL 229.A O no hydrogen 3.041 N/A ASN 233.A ND2 PHE 244.A O no hydrogen 3.327 N/A GLU 234.A N VAL 230.A O no hydrogen 3.202 N/A TRP 235.A N SER 231.A O no hydrogen 2.986 N/A ALA 236.A N PHE 232.A O no hydrogen 2.571 N/A LEU 237.A N ASN 233.A O no hydrogen 3.157 N/A ALA 238.A N TRP 235.A O no hydrogen 3.062 N/A ASN 239.A N ALA 236.A O no hydrogen 3.157 N/A ASN 239.A ND2 TRP 235.A O no hydrogen 2.529 N/A PHE 241.A N ALA 236.A O no hydrogen 3.237 N/A THR 242.A N TYR 201.A O no hydrogen 2.820 N/A THR 242.A OG1 TYR 201.A O no hydrogen 3.095 N/A THR 242.A OG1 SER 203.A OG no hydrogen 3.408 N/A PHE 244.A N ASN 233.A OD1 no hydrogen 2.884 N/A SER 249.A OG.A ASN 296.A OD1 no hydrogen 2.772 N/A SER 249.A OG.B GLU 293.A OE2 no hydrogen 3.284 N/A VAL 250.A N THR 247.A OG1 no hydrogen 3.411 N/A ASP 251.A N THR 247.A O no hydrogen 2.988 N/A MET 252.A N GLN 248.A O no hydrogen 2.921 N/A LEU 253.A N SER 249.A O no hydrogen 3.347 N/A ALA 254.A N VAL 250.A O no hydrogen 2.952 N/A VAL 255.A N ASP 251.A O no hydrogen 2.921 N/A LYS 256.A N MET 252.A O no hydrogen 3.020 N/A THR 257.A N LEU 253.A O no hydrogen 3.123 N/A THR 257.A OG1 LEU 253.A O no hydrogen 2.971 N/A GLY 258.A N ALA 254.A O no hydrogen 2.870 N/A VAL 259.A N THR 257.A OG1 no hydrogen 3.169 N/A ALA 260.A N GLN 263.A OE1 no hydrogen 2.970 N/A GLU 262.A N GLU 262.A OE1 no hydrogen 2.660 N/A GLN 263.A N ALA 260.A O no hydrogen 3.089 N/A GLN 263.A NE2 LYS 223.A O no hydrogen 3.471 N/A LEU 264.A N ILE 261.A O no hydrogen 3.045 N/A LEU 265.A N ILE 261.A O no hydrogen 3.077 N/A TYR 266.A N GLU 262.A O no hydrogen 3.173 N/A ALA 267.A N GLN 263.A O no hydrogen 3.066 N/A ILE 268.A N LEU 264.A O no hydrogen 2.783 N/A GLN 269.A N LEU 265.A O no hydrogen 3.203 N/A GLN 270.A N TYR 266.A O no hydrogen 3.123 N/A LEU 271.A N ALA 267.A O no hydrogen 2.657 N/A TYR 272.A N ILE 268.A O no hydrogen 2.838 N/A THR 273.A N GLN 270.A O no hydrogen 3.283 N/A THR 273.A OG1 GLN 270.A O no hydrogen 2.762 N/A GLY 274.A N LEU 271.A O no hydrogen 3.013 N/A LYS 278.A N PHE 275.A O no hydrogen 3.309 N/A ILE 280.A N SER 283.A O no hydrogen 2.904 N/A SER 283.A N ILE 280.A O no hydrogen 2.890 N/A SER 283.A OG MET 285.A O no hydrogen 2.739 N/A MET 285.A N SER 283.A OG no hydrogen 3.181 N/A GLU 289.A N GLU 287.A OE2 no hydrogen 3.100 N/A THR 291.A N ASP 294.A OD2 no hydrogen 3.147 N/A THR 291.A OG1 GLU 293.A OE1 no hydrogen 3.437 N/A GLU 293.A N GLU 293.A OE1 no hydrogen 2.578 N/A ASP 294.A N THR 291.A OG1 no hydrogen 2.944 N/A VAL 295.A N THR 291.A O no hydrogen 3.154 N/A ASN 296.A N PRO 292.A O no hydrogen 2.998 N/A MET 297.A N GLU 293.A O no hydrogen 2.996 N/A GLN 298.A N ASP 294.A O no hydrogen 2.932 N/A GLN 298.A NE2 VAL 6.A O no hydrogen 2.837 N/A ILE 299.A N VAL 295.A O no hydrogen 3.139 N/A VAL 302.A N ASN 296.A O no hydrogen 2.849 N/A