Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8d15_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 1.A OG1 GLU 95.A O no hydrogen 3.101 N/A LEU 4.A N PRO 97.A O no hydrogen 2.593 N/A VAL 5.A N GLY 16.A O no hydrogen 2.882 N/A CYS 6.A N LEU 99.A O no hydrogen 2.920 N/A ASP 7.A N LYS 14.A O no hydrogen 2.945 N/A ASN 8.A ND2 ASN 8.A O no hydrogen 2.247 N/A ASN 8.A ND2 THR 101.A O no hydrogen 3.482 N/A VAL 13.A N PHE 27.A O no hydrogen 3.028 N/A LYS 14.A N ASP 7.A O no hydrogen 3.475 N/A LYS 14.A NZ LEU 12.A O no hydrogen 2.884 N/A ALA 15.A N ALA 25.A O no hydrogen 3.080 N/A GLY 16.A N VAL 5.A O no hydrogen 2.899 N/A ALA 18.A N ALA 3.A O no hydrogen 3.418 N/A GLY 19.A N SER 339.A OG no hydrogen 2.786 N/A ASP 20.A N PHE 17.A O no hydrogen 3.389 N/A ARG 24.A NH2 ASP 20.A OD2 no hydrogen 3.515 N/A ALA 25.A N ALA 15.A O no hydrogen 2.824 N/A PHE 27.A N VAL 13.A O no hydrogen 3.418 N/A SER 29.A N GLY 11.A O no hydrogen 3.270 N/A VAL 31.A N LYS 64.A O no hydrogen 2.984 N/A GLY 32.A N TYR 49.A O no hydrogen 2.827 N/A ARG 33.A N THR 62.A O no hydrogen 3.376 N/A ARG 33.A NH2 ASP 76.A OD1 no hydrogen 3.552 N/A ARG 35.A N ILE 60.A O no hydrogen 3.416 N/A GLN 45.A N GLN 45.A OE1 no hydrogen 2.927 N/A SER 48.A OG ASP 47.A OD1 no hydrogen 3.339 N/A TYR 49.A N GLY 32.A O no hydrogen 2.845 N/A GLY 51.A N ILE 30.A O no hydrogen 3.224 N/A ALA 54.A N GLY 51.A O no hydrogen 2.846 N/A GLN 55.A N GLY 51.A O no hydrogen 2.939 N/A SER 56.A N ASP 52.A O no hydrogen 2.916 N/A SER 56.A OG ASP 52.A O no hydrogen 3.382 N/A LYS 57.A N ALA 54.A O no hydrogen 3.170 N/A LYS 57.A NZ GLU 53.A OE1 no hydrogen 2.800 N/A ARG 58.A N GLN 55.A O no hydrogen 3.031 N/A ILE 60.A N LYS 57.A O no hydrogen 3.302 N/A THR 62.A N ARG 33.A O no hydrogen 2.774 N/A TYR 65.A OH GLU 202.A OE1 no hydrogen 3.134 N/A GLU 68.A N ILE 70.A O no hydrogen 3.305 N/A ILE 70.A N GLU 68.A O no hydrogen 3.241 N/A ILE 71.A N ASN 110.A OD1 no hydrogen 3.096 N/A THR 72.A N PRO 66.A O no hydrogen 3.300 N/A ASP 76.A N ASN 73.A O no hydrogen 3.282 N/A MET 77.A N ASN 73.A O no hydrogen 3.145 N/A GLU 78.A N TRP 74.A O no hydrogen 2.947 N/A LYS 79.A NZ ASP 75.A O no hydrogen 3.112 N/A LYS 79.A NZ ASP 76.A OD1 no hydrogen 3.299 N/A ILE 80.A N ASP 76.A O no hydrogen 2.920 N/A TRP 81.A N MET 77.A O no hydrogen 2.928 N/A HIS 82.A N GLU 78.A O no hydrogen 2.894 N/A HIS 83.A N LYS 79.A O no hydrogen 2.881 N/A THR 84.A N ILE 80.A O no hydrogen 2.928 N/A THR 84.A OG1 ILE 80.A O no hydrogen 3.074 N/A PHE 85.A N TRP 81.A O no hydrogen 2.954 N/A TYR 86.A N HIS 82.A O no hydrogen 2.914 N/A TYR 86.A N HIS 83.A O no hydrogen 3.234 N/A ASN 87.A N HIS 83.A O no hydrogen 2.905 N/A ASN 87.A ND2 HIS 83.A ND1 no hydrogen 3.320 N/A LEU 89.A N THR 84.A O no hydrogen 3.114 N/A VAL 91.A N PHE 85.A O no hydrogen 2.962 N/A HIS 96.A N PRO 93.A O no hydrogen 2.803 N/A HIS 96.A ND1 THR 2.A O no hydrogen 2.582 N/A THR 98.A N ALA 126.A O no hydrogen 2.934 N/A THR 98.A OG1 HIS 96.A O no hydrogen 3.561 N/A LEU 99.A N LEU 4.A O no hydrogen 2.791 N/A LEU 100.A N TYR 128.A O no hydrogen 2.866 N/A THR 101.A OG1 ASP 7.A OD1 no hydrogen 3.037 N/A ASN 106.A ND2 GLY 69.A O no hydrogen 3.063 N/A ASN 110.A N PRO 107.A O no hydrogen 3.077 N/A ASN 110.A ND2 GLU 102.A OE2 no hydrogen 2.476 N/A ARG 111.A NE GLU 102.A OE1 no hydrogen 2.439 N/A ARG 111.A NH1 PHE 370.A O no hydrogen 2.496 N/A ARG 111.A NH2 GLU 102.A OE1 no hydrogen 2.703 N/A GLU 112.A N LYS 108.A O no hydrogen 2.966 N/A LYS 113.A NZ ALA 109.A O no hydrogen 2.797 N/A MET 114.A N ASN 110.A O no hydrogen 2.950 N/A THR 115.A N ARG 111.A O no hydrogen 2.884 N/A THR 115.A OG1 ARG 111.A O no hydrogen 3.123 N/A GLN 116.A N GLU 112.A O no hydrogen 2.940 N/A ILE 117.A N LYS 113.A O no hydrogen 2.883 N/A MET 118.A N MET 114.A O no hydrogen 2.967 N/A PHE 119.A N THR 115.A O no hydrogen 2.931 N/A GLU 120.A N GLN 116.A O no hydrogen 2.928 N/A THR 121.A N ILE 117.A O no hydrogen 2.909 N/A THR 121.A OG1 GLU 78.A OE2 no hydrogen 3.472 N/A ASN 123.A N MET 118.A O no hydrogen 3.038 N/A MET 127.A N ILE 352.A O no hydrogen 3.034 N/A TYR 128.A N THR 98.A O no hydrogen 3.121 N/A ALA 130.A N LEU 100.A O no hydrogen 3.049 N/A GLN 132.A NE2 ASP 7.A OD1 no hydrogen 3.057 N/A GLN 132.A NE2 THR 101.A OG1 no hydrogen 3.049 N/A LEU 135.A N ILE 131.A O no hydrogen 3.424 N/A SER 136.A N GLN 132.A O no hydrogen 2.947 N/A LEU 137.A N ALA 133.A O no hydrogen 2.917 N/A TYR 138.A N VAL 134.A O no hydrogen 2.985 N/A ALA 139.A N LEU 135.A O no hydrogen 2.942 N/A GLY 141.A N TYR 138.A O no hydrogen 2.530 N/A ARG 142.A NE ASN 291.A OD1 no hydrogen 3.605 N/A ARG 142.A NH1 SER 140.A OG no hydrogen 2.861 N/A GLY 145.A N ILE 160.A O no hydrogen 2.829 N/A ILE 146.A N ASN 291.A O no hydrogen 3.245 N/A LEU 148.A N VAL 293.A O no hydrogen 3.303 N/A ASP 149.A N HIS 156.A O no hydrogen 3.093 N/A SER 150.A OG THR 155.A OG1 no hydrogen 3.292 N/A GLY 151.A N VAL 154.A O no hydrogen 2.963 N/A THR 155.A N LEU 173.A O no hydrogen 3.061 N/A THR 155.A OG1 SER 150.A OG no hydrogen 3.292 N/A THR 155.A OG1 LEU 175.A O no hydrogen 2.730 N/A HIS 156.A N ASP 149.A O no hydrogen 2.954 N/A ASN 157.A N MET 171.A O no hydrogen 2.917 N/A VAL 158.A N VAL 147.A O no hydrogen 3.039 N/A ILE 160.A N GLY 145.A O no hydrogen 2.830 N/A GLU 162.A N THR 144.A OG1 no hydrogen 2.510 N/A TYR 164.A N TYR 161.A O no hydrogen 2.879 N/A HIS 168.A NE2 LYS 279.A O no hydrogen 2.953 N/A ALA 169.A N LEU 166.A O no hydrogen 2.957 N/A ARG 172.A NE ASP 174.A OD1 no hydrogen 2.669 N/A ARG 172.A NH1 PRO 104.A O no hydrogen 2.978 N/A ARG 172.A NH2 ASP 174.A OD2 no hydrogen 3.143 N/A LEU 173.A N THR 155.A O no hydrogen 2.511 N/A LEU 175.A N LEU 173.A O no hydrogen 2.569 N/A ARG 178.A N ASP 152.A O no hydrogen 3.201 N/A ARG 178.A NH2 SER 10.A O no hydrogen 3.215 N/A ARG 178.A NH2 ILE 67.A O no hydrogen 2.478 N/A LEU 180.A N ALA 176.A O no hydrogen 3.286 N/A THR 181.A N GLY 177.A O no hydrogen 2.903 N/A THR 181.A OG1 GLY 177.A O no hydrogen 2.548 N/A ASP 182.A N ARG 178.A O no hydrogen 2.939 N/A TYR 183.A N ASP 179.A O no hydrogen 2.913 N/A LEU 184.A N LEU 180.A O no hydrogen 2.881 N/A MET 185.A N THR 181.A O no hydrogen 2.943 N/A LYS 186.A N ASP 182.A O no hydrogen 2.897 N/A ILE 187.A N TYR 183.A O no hydrogen 2.955 N/A LEU 188.A N LEU 184.A O no hydrogen 2.909 N/A THR 189.A N LYS 186.A O no hydrogen 3.368 N/A THR 189.A OG1 LYS 186.A O no hydrogen 2.585 N/A GLU 190.A N ILE 187.A O no hydrogen 3.342 N/A ARG 191.A N LEU 188.A O no hydrogen 3.357 N/A ARG 191.A NE GLU 248.A OE1 no hydrogen 3.487 N/A ARG 191.A NE GLU 248.A OE2 no hydrogen 3.482 N/A ARG 191.A NH1 GLU 232.A OE1 no hydrogen 3.322 N/A ARG 191.A NH2 GLU 248.A OE1 no hydrogen 3.020 N/A GLY 192.A N THR 189.A O no hydrogen 2.920 N/A TYR 193.A OH THR 244.A O no hydrogen 3.397 N/A THR 197.A OG1 GLU 200.A OE1 no hydrogen 2.340 N/A ARG 201.A NE ASP 182.A OD1 no hydrogen 2.786 N/A ARG 201.A NH2 ASP 182.A OD1 no hydrogen 3.165 N/A GLU 202.A N THR 198.A O no hydrogen 2.923 N/A ILE 203.A N ALA 199.A O no hydrogen 2.981 N/A VAL 204.A N GLU 200.A O no hydrogen 2.885 N/A ARG 205.A N ARG 201.A O no hydrogen 2.862 N/A ARG 205.A NE GLU 202.A OE1 no hydrogen 3.342 N/A ARG 205.A NH1 ASP 206.A OD1 no hydrogen 3.546 N/A ARG 205.A NH1 GLU 209.A OE2 no hydrogen 2.798 N/A ASP 206.A N GLU 202.A O no hydrogen 2.969 N/A ILE 207.A N ILE 203.A O no hydrogen 2.927 N/A LYS 208.A N VAL 204.A O no hydrogen 2.875 N/A LYS 208.A NZ GLY 177.A O no hydrogen 3.169 N/A LYS 208.A NZ THR 181.A OG1 no hydrogen 3.305 N/A GLU 209.A N ARG 205.A O no hydrogen 2.936 N/A LYS 210.A N ASP 206.A O no hydrogen 2.886 N/A LEU 211.A N ILE 207.A O no hydrogen 2.919 N/A CYS 212.A N LYS 208.A O no hydrogen 3.250 N/A CYS 212.A SG ARG 249.A O no hydrogen 3.322 N/A TYR 213.A N ARG 249.A O no hydrogen 3.363 N/A TYR 213.A OH GLU 221.A OE1 no hydrogen 2.869 N/A GLU 221.A N ASP 217.A O no hydrogen 2.954 N/A MET 222.A N PHE 218.A O no hydrogen 2.891 N/A ALA 223.A N GLU 219.A O no hydrogen 2.954 N/A THR 224.A N ASN 220.A O no hydrogen 2.891 N/A THR 224.A OG1 ASN 220.A O no hydrogen 2.930 N/A THR 224.A OG1 ASN 220.A OD1 no hydrogen 3.304 N/A ALA 225.A N GLU 221.A O no hydrogen 2.903 N/A ALA 226.A N MET 222.A O no hydrogen 2.911 N/A SER 227.A N ALA 223.A O no hydrogen 2.944 N/A SER 227.A N THR 224.A O no hydrogen 3.055 N/A SER 227.A OG ALA 223.A O no hydrogen 2.955 N/A SER 227.A OG THR 224.A O no hydrogen 3.009 N/A SER 228.A N ALA 225.A O no hydrogen 3.383 N/A SER 228.A OG THR 224.A O no hydrogen 3.079 N/A SER 228.A OG SER 230.A OG no hydrogen 3.323 N/A SER 230.A OG SER 228.A OG no hydrogen 3.323 N/A LYS 233.A N ILE 245.A O no hydrogen 3.056 N/A TYR 235.A N ILE 243.A O no hydrogen 3.006 N/A LEU 237.A N GLN 241.A O no hydrogen 2.802 N/A GLY 240.A N LEU 237.A O no hydrogen 3.196 N/A GLN 241.A N ASP 239.A OD1 no hydrogen 3.204 N/A ILE 243.A N TYR 235.A O no hydrogen 2.830 N/A THR 244.A N TYR 193.A OH no hydrogen 3.256 N/A ILE 245.A N LYS 233.A O no hydrogen 3.026 N/A GLY 246.A N GLU 248.A OE1 no hydrogen 3.421 N/A GLU 248.A N GLU 248.A OE1 no hydrogen 2.823 N/A ARG 249.A N GLY 246.A O no hydrogen 3.006 N/A ARG 249.A NE LEU 211.A O no hydrogen 3.539 N/A ARG 249.A NH1 LEU 231.A O no hydrogen 2.656 N/A ARG 249.A NH2 LEU 211.A O no hydrogen 3.444 N/A ARG 251.A N ASN 247.A O no hydrogen 2.942 N/A ARG 251.A NH1 GLU 190.A OE1 no hydrogen 3.230 N/A ARG 251.A NH1 GLU 190.A OE2 no hydrogen 3.461 N/A ARG 251.A NH1 ASN 247.A OD1 no hydrogen 2.795 N/A ARG 251.A NH2 GLU 190.A OE2 no hydrogen 3.226 N/A CYS 252.A N GLU 248.A O no hydrogen 2.967 N/A CYS 252.A SG LEU 180.A O no hydrogen 3.408 N/A THR 255.A N CYS 252.A O no hydrogen 3.276 N/A THR 255.A OG1 CYS 252.A O no hydrogen 3.345 N/A LEU 256.A N PRO 253.A O no hydrogen 2.958 N/A PHE 257.A N GLU 254.A O no hydrogen 2.806 N/A GLN 258.A N THR 255.A O no hydrogen 3.148 N/A PHE 261.A N GLN 258.A O no hydrogen 2.981 N/A ILE 262.A N PRO 259.A O no hydrogen 2.730 N/A ILE 269.A N LEU 256.A O no hydrogen 3.193 N/A THR 272.A N GLY 268.A O no hydrogen 3.140 N/A THR 272.A OG1 GLY 268.A O no hydrogen 2.948 N/A THR 273.A N ILE 269.A O no hydrogen 2.929 N/A THR 273.A OG1 ILE 269.A O no hydrogen 3.146 N/A TYR 274.A N HIS 270.A O no hydrogen 2.978 N/A ASN 275.A N GLU 271.A O no hydrogen 2.868 N/A SER 276.A N THR 272.A O no hydrogen 2.904 N/A SER 276.A OG ALA 169.A O no hydrogen 2.505 N/A ILE 277.A N THR 273.A O no hydrogen 2.948 N/A MET 278.A N TYR 274.A O no hydrogen 2.881 N/A LYS 279.A N ASN 275.A O no hydrogen 3.100 N/A LYS 279.A N SER 276.A O no hydrogen 3.333 N/A CYS 280.A N ILE 277.A O no hydrogen 2.775 N/A CYS 280.A SG SER 276.A O no hydrogen 3.496 N/A ILE 284.A N ASP 281.A O no hydrogen 3.173 N/A ARG 285.A NE CYS 280.A O no hydrogen 2.762 N/A ARG 285.A NH2 CYS 280.A O no hydrogen 2.942 N/A ASP 287.A N ILE 284.A O no hydrogen 2.643 N/A LEU 288.A N ILE 284.A O no hydrogen 3.010 N/A TYR 289.A N ARG 285.A O no hydrogen 2.937 N/A ASN 291.A N LEU 288.A O no hydrogen 3.068 N/A ASN 291.A ND2 ASP 287.A O no hydrogen 2.548 N/A VAL 293.A N ILE 146.A O no hydrogen 3.019 N/A MET 294.A N ILE 325.A O no hydrogen 3.087 N/A THR 298.A N SER 150.A O no hydrogen 3.301 N/A THR 298.A OG1 GLY 151.A O no hydrogen 2.752 N/A THR 299.A N GLY 296.A O no hydrogen 3.366 N/A THR 299.A OG1 SER 295.A O no hydrogen 2.410 N/A THR 299.A OG1 GLY 296.A O no hydrogen 2.794 N/A MET 300.A N GLY 297.A O no hydrogen 2.751 N/A ILE 304.A N TYR 301.A O no hydrogen 3.314 N/A ARG 307.A N GLY 303.A O no hydrogen 3.327 N/A ARG 307.A NE GLU 311.A OE2 no hydrogen 2.597 N/A ARG 307.A NH1 ALA 215.A O no hydrogen 3.166 N/A ARG 307.A NH1 GLU 254.A OE1 no hydrogen 3.307 N/A ARG 307.A NH1 GLU 254.A OE2 no hydrogen 2.657 N/A ARG 307.A NH2 GLU 254.A OE2 no hydrogen 2.843 N/A ARG 307.A NH2 GLU 311.A OE2 no hydrogen 3.134 N/A MET 308.A N ILE 304.A O no hydrogen 2.943 N/A GLN 309.A N ALA 305.A O no hydrogen 2.904 N/A GLN 309.A NE2 ILE 322.A O no hydrogen 2.731 N/A LYS 310.A N ASP 306.A O no hydrogen 2.909 N/A GLU 311.A N ARG 307.A O no hydrogen 2.932 N/A ILE 312.A N MET 308.A O no hydrogen 2.939 N/A THR 313.A N GLN 309.A O no hydrogen 2.898 N/A THR 313.A OG1 GLN 309.A O no hydrogen 2.568 N/A ALA 314.A N LYS 310.A O no hydrogen 2.958 N/A LEU 315.A N GLU 311.A O no hydrogen 2.932 N/A ALA 316.A N ILE 312.A O no hydrogen 2.874 N/A LYS 323.A N TYR 289.A O no hydrogen 3.451 N/A ILE 325.A N ASN 292.A O no hydrogen 2.682 N/A ARG 330.A N PRO 327.A O no hydrogen 3.189 N/A ARG 330.A NE THR 299.A O no hydrogen 3.324 N/A ARG 330.A NH1 PRO 327.A O no hydrogen 2.928 N/A ARG 330.A NH2 THR 299.A O no hydrogen 3.210 N/A TYR 332.A N GLU 329.A O no hydrogen 3.227 N/A ILE 336.A N TYR 332.A O no hydrogen 2.863 N/A GLY 337.A N SER 333.A O no hydrogen 2.889 N/A GLY 338.A N VAL 334.A O no hydrogen 2.919 N/A SER 339.A N TRP 335.A O no hydrogen 2.855 N/A SER 339.A OG ASP 20.A O no hydrogen 2.793 N/A ILE 340.A N ILE 336.A O no hydrogen 2.951 N/A LEU 341.A N GLY 337.A O no hydrogen 2.859 N/A ALA 342.A N GLY 338.A O no hydrogen 2.909 N/A SER 343.A N ILE 340.A O no hydrogen 3.093 N/A SER 343.A OG SER 339.A O no hydrogen 3.140 N/A LEU 344.A N LEU 341.A O no hydrogen 3.183 N/A PHE 347.A N LEU 344.A O no hydrogen 3.203 N/A GLN 348.A N SER 345.A O no hydrogen 3.428 N/A MET 350.A N PHE 347.A O no hydrogen 2.970 N/A ILE 352.A N MET 127.A O no hydrogen 2.872 N/A LYS 354.A N PRO 125.A O no hydrogen 2.996 N/A LYS 354.A NZ ASP 358.A OD1 no hydrogen 2.681 N/A LYS 354.A NZ ASP 358.A OD2 no hydrogen 2.728 N/A TYR 357.A N THR 353.A O no hydrogen 3.192 N/A ASP 358.A N LYS 354.A O no hydrogen 2.950 N/A GLU 359.A N GLN 355.A O no hydrogen 2.891 N/A ALA 360.A N GLU 356.A O no hydrogen 2.903 N/A GLY 361.A N TYR 357.A O no hydrogen 2.739 N/A ILE 364.A N GLY 361.A O no hydrogen 3.151 N/A VAL 365.A N PRO 362.A O no hydrogen 3.249 N/A HIS 366.A N SER 363.A O no hydrogen 2.929 N/A HIS 366.A NE2 GLU 112.A OE2 no hydrogen 3.051 N/A ARG 367.A N ILE 364.A O no hydrogen 2.775 N/A LYS 368.A N ILE 364.A O no hydrogen 2.941 N/A LYS 368.A NZ GLU 356.A OE1 no hydrogen 2.688 N/A LYS 368.A NZ GLU 356.A OE2 no hydrogen 2.816 N/A CYS 369.A N VAL 365.A O no hydrogen 3.194 N/A