Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8d4s_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 1.A N GLY 128.A O no hydrogen 3.450 N/A ILE 1.A N ARG 129.A O no hydrogen 2.867 N/A ILE 1.A N ASP 180.A OD2 no hydrogen 2.751 N/A ILE 2.A N ALA 175.A O no hydrogen 2.755 N/A ARG 5.A N GLU 141.A O no hydrogen 2.907 N/A SER 7.A N LEU 139.A O no hydrogen 2.794 N/A SER 7.A OG LEU 139.A O no hydrogen 3.425 N/A SER 7.A OG GLU 141.A OE1 no hydrogen 2.852 N/A HIS 10.A NE2 THR 65.A OG1 no hydrogen 3.102 N/A SER 11.A N ARG 8.A O no hydrogen 3.094 N/A SER 11.A OG ARG 8.A O no hydrogen 2.602 N/A ARG 12.A NE GLU 141.A OE1 no hydrogen 2.788 N/A ARG 12.A NH1 TYR 14.A OH no hydrogen 2.846 N/A ARG 12.A NH2 GLU 141.A OE1 no hydrogen 3.513 N/A ARG 12.A NH2 GLU 141.A OE2 no hydrogen 2.979 N/A MET 15.A N ARG 12.A O no hydrogen 3.115 N/A ALA 16.A N GLY 31.A O no hydrogen 2.880 N/A TYR 17.A N THR 53.A O no hydrogen 2.898 N/A LEU 18.A N CYS 29.A O no hydrogen 2.913 N/A GLN 19.A N ASN 51.A O no hydrogen 2.886 N/A ILE 20.A N SER 27.A O no hydrogen 2.862 N/A GLN 21.A N ASN 49.A O no hydrogen 2.967 N/A SER 22.A N GLY 25.A O no hydrogen 3.009 N/A SER 22.A OG SER 22.A O no hydrogen 2.422 N/A SER 22.A OG SER 27.A OG no hydrogen 3.417 N/A GLY 25.A N SER 22.A O no hydrogen 2.509 N/A SER 27.A N ILE 20.A O no hydrogen 2.845 N/A SER 27.A OG SER 22.A OG no hydrogen 3.417 N/A ARG 28.A NH1 SER 27.A O no hydrogen 3.209 N/A CYS 29.A N LEU 18.A O no hydrogen 3.175 N/A GLY 30.A N SER 181.A O no hydrogen 2.750 N/A PHE 32.A N LEU 40.A O no hydrogen 2.980 N/A LEU 33.A N TYR 14.A O no hydrogen 2.743 N/A VAL 34.A N PHE 38.A O no hydrogen 2.951 N/A ARG 35.A N PHE 38.A O no hydrogen 3.434 N/A ARG 35.A NE ASP 37.A OD1 no hydrogen 2.956 N/A ARG 35.A NH1 MET 222.A O no hydrogen 3.548 N/A ARG 35.A NH2 ASP 37.A OD1 no hydrogen 3.439 N/A ARG 35.A NH2 ASP 37.A OD2 no hydrogen 3.044 N/A ARG 35.A NH2 MET 222.A O no hydrogen 3.014 N/A PHE 38.A N ARG 35.A O no hydrogen 3.056 N/A VAL 39.A N LEU 92.A O no hydrogen 2.894 N/A LEU 40.A N PHE 32.A O no hydrogen 2.837 N/A THR 41.A N MET 90.A O no hydrogen 2.919 N/A THR 41.A OG1 GLY 30.A O no hydrogen 2.816 N/A ALA 42.A N THR 41.A OG1 no hydrogen 2.757 N/A HIS 44.A N ASP 88.A OD1 no hydrogen 2.962 N/A HIS 44.A ND1 ASP 88.A OD2 no hydrogen 2.733 N/A HIS 44.A NE2 SER 181.A OG no hydrogen 2.588 N/A CYS 45.A N ALA 42.A O no hydrogen 3.127 N/A TRP 46.A N ALA 43.A O no hydrogen 3.109 N/A ASN 51.A N GLN 19.A O no hydrogen 2.928 N/A VAL 52.A N ILE 69.A O no hydrogen 2.833 N/A THR 53.A N TYR 17.A O no hydrogen 2.818 N/A THR 53.A OG1 HIS 68.A ND1 no hydrogen 3.063 N/A LEU 54.A N GLN 67.A O no hydrogen 2.945 N/A HIS 57.A N GLU 63.A OE1 no hydrogen 2.788 N/A HIS 57.A NE2 GLU 6.A OE2 no hydrogen 2.991 N/A ASN 58.A N GLU 63.A OE1 no hydrogen 3.251 N/A ASN 58.A N GLU 63.A OE2 no hydrogen 2.837 N/A ILE 59.A N ASP 137.A O no hydrogen 3.015 N/A GLN 60.A N ASN 58.A OD1 no hydrogen 3.115 N/A ARG 61.A N ASN 58.A O no hydrogen 3.289 N/A THR 65.A OG1 HIS 10.A NE2 no hydrogen 3.102 N/A THR 65.A OG1 GLY 55.A O no hydrogen 2.680 N/A GLN 66.A N GLU 63.A O no hydrogen 3.330 N/A GLN 66.A NE2 ASN 58.A O no hydrogen 3.192 N/A GLN 66.A NE2 ARG 61.A O no hydrogen 2.934 N/A GLN 66.A NE2 GLU 63.A OE1 no hydrogen 2.883 N/A GLN 67.A N LEU 54.A O no hydrogen 2.833 N/A GLN 67.A NE2 ARG 99.A O no hydrogen 2.769 N/A HIS 68.A ND1 THR 53.A OG1 no hydrogen 3.063 N/A ILE 69.A N VAL 52.A O no hydrogen 2.902 N/A THR 70.A OG1 SER 95.A OG no hydrogen 3.105 N/A ALA 71.A N ILE 50.A O no hydrogen 2.944 N/A ARG 72.A N GLN 93.A O no hydrogen 2.702 N/A ARG 72.A NH1 ARG 72.A O no hydrogen 3.447 N/A ARG 73.A N GLN 93.A O no hydrogen 3.385 N/A ARG 73.A NH1 GLN 93.A OE1 no hydrogen 2.963 N/A ILE 75.A N LEU 91.A O no hydrogen 2.770 N/A HIS 77.A N ILE 89.A O no hydrogen 2.962 N/A GLN 79.A N HIS 77.A ND1 no hydrogen 2.973 N/A TYR 80.A N HIS 77.A O no hydrogen 3.058 N/A ASN 81.A N GLN 86.A O no hydrogen 3.007 N/A ARG 83.A N ASN 81.A OD1 no hydrogen 3.027 N/A THR 84.A N ASN 81.A OD1 no hydrogen 3.309 N/A GLN 86.A N ASN 81.A O no hydrogen 3.193 N/A GLN 86.A NE2 GLN 164.A OE1 no hydrogen 3.253 N/A ASN 87.A N GLN 86.A OE1 no hydrogen 2.940 N/A ASN 87.A ND2 GLN 79.A O no hydrogen 2.960 N/A ILE 89.A N ASN 87.A O no hydrogen 2.996 N/A MET 90.A N THR 41.A O no hydrogen 2.928 N/A LEU 91.A N ILE 75.A O no hydrogen 2.898 N/A LEU 92.A N VAL 39.A O no hydrogen 2.754 N/A GLN 93.A N ARG 73.A O no hydrogen 2.925 N/A LEU 94.A N ASP 37.A O no hydrogen 2.724 N/A SER 95.A N THR 70.A O no hydrogen 2.882 N/A SER 95.A OG THR 70.A O no hydrogen 3.055 N/A SER 95.A OG THR 70.A OG1 no hydrogen 3.105 N/A ARG 96.A NH1 HIS 68.A O no hydrogen 3.399 N/A ARG 96.A NH2 HIS 68.A O no hydrogen 3.101 N/A ARG 97.A NE GLU 36.A OE1 no hydrogen 3.325 N/A VAL 98.A N GLU 36.A O no hydrogen 2.947 N/A ARG 99.A N GLN 67.A OE1 no hydrogen 2.763 N/A ASN 101.A N VAL 104.A O no hydrogen 2.930 N/A ASN 103.A N ASN 101.A OD1 no hydrogen 2.804 N/A VAL 104.A N ASN 101.A O no hydrogen 3.123 N/A ASN 105.A N PRO 13.A O no hydrogen 3.237 N/A ASN 105.A ND2 ASN 101.A O no hydrogen 2.868 N/A ASN 105.A ND2 ARG 102.A O no hydrogen 3.487 N/A VAL 107.A N LEU 33.A O no hydrogen 2.910 N/A ARG 111.A N GLU 114.A OE1 no hydrogen 3.154 N/A GLN 113.A NE2 SER 213.A OG no hydrogen 3.405 N/A GLU 114.A N ARG 111.A O no hydrogen 2.870 N/A GLY 119.A N VAL 146.A O no hydrogen 2.706 N/A THR 120.A N ARG 117.A O no hydrogen 3.009 N/A THR 120.A OG1 ARG 117.A O no hydrogen 2.913 N/A CYS 122.A N LEU 144.A O no hydrogen 2.825 N/A THR 123.A N LEU 186.A O no hydrogen 2.751 N/A VAL 124.A N VAL 142.A O no hydrogen 3.050 N/A GLY 126.A N ARG 140.A O no hydrogen 2.975 N/A TRP 127.A NE1 HIS 57.A O no hydrogen 2.953 N/A GLY 128.A N ASP 180.A OD1 no hydrogen 2.700 N/A ARG 129.A N LYS 178.A O no hydrogen 2.764 N/A VAL 130.A N ARG 134.A O no hydrogen 2.957 N/A ARG 133.A N SER 131.A OG no hydrogen 2.910 N/A THR 136.A OG1 THR 138.A O no hydrogen 2.859 N/A THR 138.A N THR 136.A OG1 no hydrogen 3.123 N/A LEU 139.A N HIS 57.A O no hydrogen 3.187 N/A ARG 140.A N GLY 126.A O no hydrogen 3.131 N/A ARG 140.A NH2 GLY 4.A O no hydrogen 3.005 N/A GLU 141.A N ARG 5.A O no hydrogen 2.827 N/A VAL 142.A N VAL 124.A O no hydrogen 3.001 N/A LEU 144.A N CYS 122.A O no hydrogen 2.662 N/A VAL 146.A N THR 120.A O no hydrogen 3.068 N/A GLN 147.A N CYS 166.A O no hydrogen 2.767 N/A GLN 147.A NE2 ARG 145.A O no hydrogen 2.988 N/A GLN 151.A N ARG 148.A O no hydrogen 3.187 N/A CYS 152.A N ASP 149.A O no hydrogen 2.938 N/A LEU 153.A N ASP 149.A O no hydrogen 2.884 N/A ARG 154.A N ARG 150.A O no hydrogen 3.336 N/A ILE 155.A N CYS 152.A O no hydrogen 3.254 N/A PHE 156.A N CYS 152.A O no hydrogen 2.827 N/A TYR 159.A N PHE 156.A O no hydrogen 3.114 N/A TYR 159.A OH ASP 149.A OD1 no hydrogen 3.164 N/A TYR 159.A OH GLN 164.A O no hydrogen 3.312 N/A ASP 160.A N GLN 164.A OE1 no hydrogen 2.860 N/A ARG 162.A N ASP 160.A OD1 no hydrogen 2.966 N/A ARG 163.A N ASP 160.A O no hydrogen 3.017 N/A ARG 163.A NE ASN 87.A OD1 no hydrogen 3.168 N/A ARG 163.A NH1 ASP 160.A OD2 no hydrogen 3.320 N/A ILE 165.A N PHE 208.A O no hydrogen 2.721 N/A CYS 166.A SG ARG 148.A O no hydrogen 3.830 N/A VAL 167.A N GLU 206.A O no hydrogen 2.943 N/A GLY 168.A N ARG 145.A O no hydrogen 2.965 N/A ARG 171.A N ASP 169.A OD1 no hydrogen 2.967 N/A ARG 171.A NE ASP 169.A OD1 no hydrogen 2.968 N/A ARG 171.A NH2 ASP 169.A OD2 no hydrogen 2.628 N/A GLU 172.A N ASP 169.A O no hydrogen 3.134 N/A LYS 174.A NZ GLU 172.A OE2 no hydrogen 2.628 N/A ALA 175.A N ILE 2.A O no hydrogen 3.251 N/A ALA 176.A N GLU 206.A OE2 no hydrogen 2.838 N/A PHE 177.A N ASP 180.A OD2 no hydrogen 2.699 N/A ASP 180.A N PHE 177.A O no hydrogen 2.909 N/A SER 181.A OG HIS 44.A NE2 no hydrogen 2.588 N/A SER 181.A OG SER 196.A O no hydrogen 3.481 N/A GLY 182.A N VAL 195.A O no hydrogen 3.008 N/A GLY 183.A N ASP 180.A O no hydrogen 3.055 N/A LEU 185.A N GLY 193.A O no hydrogen 2.839 N/A LEU 186.A N THR 123.A O no hydrogen 2.771 N/A CYS 187.A N VAL 190.A O no hydrogen 2.986 N/A VAL 190.A N CYS 187.A O no hydrogen 3.202 N/A ALA 191.A N ALA 108.A O no hydrogen 3.053 N/A HIS 192.A N LEU 185.A O no hydrogen 2.904 N/A HIS 192.A ND1 VAL 190.A O no hydrogen 3.346 N/A HIS 192.A NE2 GLU 114.A OE2 no hydrogen 3.205 N/A ILE 194.A N THR 209.A O no hydrogen 3.064 N/A VAL 195.A N GLY 183.A O no hydrogen 2.875 N/A SER 196.A N VAL 207.A O no hydrogen 3.310 N/A SER 196.A OG ASP 88.A OD2 no hydrogen 2.716 N/A TYR 197.A N VAL 207.A O no hydrogen 3.126 N/A GLY 202.A N LYS 199.A O no hydrogen 2.981 N/A VAL 203.A N SER 201.A OG no hydrogen 3.216 N/A GLU 206.A N VAL 167.A O no hydrogen 2.796 N/A VAL 207.A N TYR 197.A O no hydrogen 2.906 N/A PHE 208.A N ILE 165.A O no hydrogen 2.908 N/A THR 209.A N ILE 194.A O no hydrogen 2.925 N/A THR 209.A OG1 ASP 88.A O no hydrogen 2.888 N/A ARG 210.A N ARG 163.A O no hydrogen 2.804 N/A ARG 210.A NE PRO 161.A O no hydrogen 3.308 N/A ARG 210.A NE GLN 164.A O no hydrogen 3.277 N/A ARG 210.A NH2 PRO 161.A O no hydrogen 3.432 N/A ARG 210.A NH2 GLN 164.A O no hydrogen 3.011 N/A VAL 211.A N HIS 192.A O no hydrogen 2.869 N/A SER 212.A OG GLU 114.A O no hydrogen 3.120 N/A SER 213.A N ARG 210.A O no hydrogen 3.068 N/A SER 213.A OG ARG 162.A O no hydrogen 2.396 N/A PHE 214.A N VAL 211.A O no hydrogen 2.877 N/A ILE 218.A N PHE 214.A O no hydrogen 2.817 N/A ARG 219.A N LEU 215.A O no hydrogen 2.971 N/A THR 220.A N PRO 216.A O no hydrogen 3.089 N/A THR 220.A OG1 PRO 216.A O no hydrogen 3.357 N/A THR 221.A N TRP 217.A O no hydrogen 3.036 N/A THR 221.A OG1 TRP 217.A O no hydrogen 2.707 N/A MET 222.A N ILE 218.A O no hydrogen 3.047 N/A ARG 223.A N THR 220.A O no hydrogen 3.324 N/A