Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8de0_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PRO 1.A N GLU 2.A OE1 no hydrogen 3.243 N/A THR 3.A OG1 SER 257.A OG no hydrogen 2.716 N/A VAL 5.A N PRO 1.A O no hydrogen 3.039 N/A LYS 6.A N GLU 2.A O no hydrogen 3.063 N/A LYS 6.A NZ GLU 253.A OE1 no hydrogen 3.433 N/A VAL 7.A N THR 3.A O no hydrogen 3.132 N/A LYS 8.A N LEU 4.A O no hydrogen 3.043 N/A ASP 9.A N VAL 5.A O no hydrogen 2.778 N/A ALA 10.A N LYS 6.A O no hydrogen 2.762 N/A GLU 11.A N VAL 7.A O no hydrogen 2.902 N/A ASP 12.A N LYS 8.A O no hydrogen 3.012 N/A GLN 13.A N ASP 9.A O no hydrogen 2.825 N/A LEU 14.A N ALA 10.A O no hydrogen 2.727 N/A ALA 16.A N GLU 11.A O no hydrogen 3.268 N/A ARG 17.A NH1 GLU 38.A OE1 no hydrogen 2.831 N/A ARG 17.A NH1 ARG 39.A O no hydrogen 3.213 N/A ARG 17.A NH2 ARG 39.A O no hydrogen 3.122 N/A VAL 18.A N GLU 11.A OE2 no hydrogen 2.807 N/A GLY 19.A N TYR 236.A O no hydrogen 2.670 N/A TYR 20.A N PHE 34.A O no hydrogen 2.874 N/A TYR 20.A OH GLU 32.A OE2 no hydrogen 2.918 N/A ILE 21.A N VAL 234.A O no hydrogen 2.992 N/A GLU 22.A N GLU 32.A O no hydrogen 2.919 N/A LEU 23.A N ILE 232.A O.A no hydrogen 2.776 N/A LEU 23.A N ILE 232.A O.B no hydrogen 2.721 N/A ASP 24.A N LYS 29.A O no hydrogen 3.013 N/A LEU 25.A N SER 230.A O no hydrogen 3.066 N/A ASN 26.A N ASP 24.A OD1 no hydrogen 3.149 N/A SER 27.A N ASP 24.A OD2 no hydrogen 3.375 N/A SER 27.A OG ASP 24.A OD2 no hydrogen 2.598 N/A GLY 28.A N ASP 24.A O no hydrogen 2.690 N/A LYS 29.A N SER 27.A OG no hydrogen 3.095 N/A LEU 31.A N GLU 22.A O no hydrogen 2.761 N/A GLU 32.A N GLU 22.A O no hydrogen 3.300 N/A PHE 34.A N TYR 20.A O no hydrogen 2.815 N/A ARG 35.A NE GLU 11.A OE2 no hydrogen 2.584 N/A ARG 35.A NH1 GLU 38.A OE2 no hydrogen 2.895 N/A ARG 35.A NH2 GLU 11.A OE1 no hydrogen 2.929 N/A GLU 38.A N ARG 35.A O no hydrogen 3.241 N/A ARG 39.A NH1 VAL 133.A O no hydrogen 2.894 N/A ARG 39.A NH1 THR 154.A OG1 no hydrogen 2.986 N/A ARG 39.A NH2 VAL 133.A O no hydrogen 2.996 N/A PHE 40.A N THR 155.A O no hydrogen 2.979 N/A MET 42.A N ASP 153.A O no hydrogen 3.172 N/A SER 44.A OG SER 104.A OG no hydrogen 2.893 N/A THR 45.A N MET 42.A O no hydrogen 3.190 N/A THR 45.A OG1 MET 42.A O no hydrogen 2.484 N/A THR 45.A OG1 TYR 236.A OH no hydrogen 2.847 N/A PHE 46.A N MET 43.A O no hydrogen 3.190 N/A LYS 47.A N SER 44.A O no hydrogen 3.101 N/A LYS 47.A NZ SER 44.A OG no hydrogen 3.200 N/A LYS 47.A NZ SER 104.A O no hydrogen 2.962 N/A LYS 47.A NZ SER 104.A OG no hydrogen 3.331 N/A LYS 47.A NZ ASN 106.A OD1 no hydrogen 2.664 N/A VAL 48.A N THR 45.A O no hydrogen 3.414 N/A LEU 50.A N PHE 46.A O no hydrogen 2.950 N/A CYS 51.A N LYS 47.A O no hydrogen 3.017 N/A CYS 51.A SG LYS 47.A O no hydrogen 3.673 N/A GLY 52.A N VAL 48.A O no hydrogen 2.832 N/A ALA 53.A N LEU 49.A O no hydrogen 2.921 N/A VAL 54.A N LEU 50.A O no hydrogen 2.915 N/A LEU 55.A N CYS 51.A O no hydrogen 2.872 N/A SER 56.A N.A GLY 52.A O no hydrogen 2.916 N/A SER 56.A N.B GLY 52.A O no hydrogen 2.919 N/A SER 56.A OG.A GLY 52.A O no hydrogen 3.223 N/A SER 56.A OG.A ALA 53.A O no hydrogen 2.394 N/A ARG 57.A N ALA 53.A O no hydrogen 3.149 N/A VAL 58.A N VAL 54.A O no hydrogen 2.888 N/A ASP 59.A N LEU 55.A O no hydrogen 2.776 N/A ALA 60.A N SER 56.A O.A no hydrogen 3.129 N/A ALA 60.A N SER 56.A O.B no hydrogen 3.124 N/A GLY 61.A N VAL 58.A O no hydrogen 3.053 N/A GLN 62.A N ARG 57.A O no hydrogen 2.870 N/A GLU 63.A N ARG 57.A O no hydrogen 3.338 N/A GLN 64.A N GLU 63.A OE2 no hydrogen 3.070 N/A GLN 64.A NE2 GLY 61.A O no hydrogen 3.596 N/A ARG 67.A N GLN 64.A O no hydrogen 3.021 N/A ARG 67.A NE GLU 63.A OE2 no hydrogen 2.578 N/A ARG 67.A NH2 GLU 63.A OE1 no hydrogen 2.763 N/A ARG 67.A NH2 GLU 63.A OE2 no hydrogen 3.220 N/A ARG 68.A NH1 ASP 89.A O no hydrogen 3.007 N/A ILE 69.A N MET 91.A O no hydrogen 2.723 N/A TYR 71.A OH THR 83.A O no hydrogen 2.641 N/A SER 72.A N ASP 75.A OD2 no hydrogen 2.664 N/A ASP 75.A N SER 72.A O no hydrogen 2.750 N/A LEU 76.A N GLN 73.A O no hydrogen 3.356 N/A VAL 77.A N THR 107.A OG1 no hydrogen 3.122 N/A TYR 79.A OH MET 103.A O no hydrogen 2.780 N/A SER 80.A OG VAL 77.A O no hydrogen 2.682 N/A SER 80.A OG THR 107.A OG1 no hydrogen 2.356 N/A VAL 82.A N ASP 105.A OD2 no hydrogen 2.966 N/A THR 83.A N ASP 105.A OD2 no hydrogen 2.950 N/A THR 83.A OG1 ASP 105.A OD1 no hydrogen 2.946 N/A THR 83.A OG1 ASP 105.A OD2 no hydrogen 3.023 N/A GLU 84.A N SER 80.A O no hydrogen 3.121 N/A LYS 85.A N VAL 82.A O no hydrogen 2.871 N/A HIS 86.A N THR 83.A O no hydrogen 3.391 N/A HIS 86.A ND1 ASP 89.A OD2 no hydrogen 2.780 N/A ASP 89.A N ASP 89.A OD1 no hydrogen 2.700 N/A MET 91.A N ILE 69.A O no hydrogen 2.933 N/A THR 92.A N GLU 95.A OE1 no hydrogen 3.071 N/A VAL 93.A N ARG 67.A O no hydrogen 2.928 N/A ARG 94.A N LEU 65.A O no hydrogen 2.950 N/A GLU 95.A N THR 92.A OG1 no hydrogen 3.202 N/A LEU 96.A N THR 92.A O no hydrogen 2.834 N/A CYS 97.A N VAL 93.A O no hydrogen 2.880 N/A SER 98.A N ARG 94.A O no hydrogen 2.874 N/A ALA 99.A N GLU 95.A O no hydrogen 2.900 N/A ALA 100.A N LEU 96.A O no hydrogen 2.846 N/A ILE 101.A N CYS 97.A O no hydrogen 3.040 N/A THR 102.A N SER 98.A O no hydrogen 2.945 N/A THR 102.A OG1 SER 98.A O no hydrogen 2.578 N/A MET 103.A N ALA 99.A O no hydrogen 3.267 N/A SER 104.A OG SER 44.A OG no hydrogen 2.893 N/A ASP 105.A N ALA 99.A O no hydrogen 2.930 N/A ASN 106.A N TYR 79.A O no hydrogen 2.818 N/A ASN 106.A ND2 GLU 78.A O no hydrogen 3.161 N/A THR 107.A OG1 SER 80.A OG no hydrogen 2.356 N/A ALA 108.A N ASP 105.A OD1 no hydrogen 2.901 N/A ALA 109.A N ASP 105.A O no hydrogen 3.388 N/A ASN 110.A N ASN 106.A O no hydrogen 3.126 N/A ASN 110.A ND2 GLU 140.A O no hydrogen 2.961 N/A LEU 111.A N THR 107.A O no hydrogen 2.901 N/A LEU 112.A N ALA 108.A O no hydrogen 2.973 N/A LEU 113.A N ALA 109.A O no hydrogen 2.999 N/A THR 114.A N ASN 110.A O no hydrogen 3.011 N/A THR 114.A OG1 ASN 110.A O no hydrogen 3.303 N/A THR 115.A N LEU 111.A O no hydrogen 3.222 N/A THR 115.A OG1 LEU 112.A O no hydrogen 2.543 N/A ILE 116.A N LEU 112.A O no hydrogen 3.324 N/A ILE 116.A N LEU 113.A O no hydrogen 3.132 N/A GLY 117.A N THR 114.A O no hydrogen 3.230 N/A GLY 118.A N LEU 113.A O no hydrogen 2.739 N/A GLU 121.A N GLY 118.A O no hydrogen 2.997 N/A LEU 122.A N GLY 118.A O no hydrogen 3.207 N/A THR 123.A N PRO 119.A O no hydrogen 2.985 N/A THR 123.A OG1 PRO 119.A O no hydrogen 3.207 N/A THR 123.A OG1 LEU 136.A O no hydrogen 2.834 N/A ALA 124.A N LYS 120.A O no hydrogen 3.028 N/A PHE 125.A N GLU 121.A O no hydrogen 2.943 N/A LEU 126.A N LEU 122.A O no hydrogen 3.020 N/A HIS 127.A N THR 123.A O no hydrogen 2.820 N/A ASN 128.A N ALA 124.A O no hydrogen 2.993 N/A MET 129.A N PHE 125.A O no hydrogen 3.182 N/A MET 129.A N LEU 126.A O no hydrogen 3.132 N/A GLY 130.A N HIS 127.A O no hydrogen 2.955 N/A ASP 131.A N LEU 126.A O no hydrogen 2.895 N/A VAL 133.A N ASP 131.A OD1 no hydrogen 2.937 N/A THR 134.A N ASP 131.A OD1 no hydrogen 2.853 N/A THR 134.A OG1 ASP 131.A OD1 no hydrogen 3.247 N/A THR 134.A OG1 ASP 131.A OD2 no hydrogen 2.623 N/A THR 134.A OG1 THR 155.A OG1 no hydrogen 2.734 N/A ARG 135.A N THR 154.A O no hydrogen 3.055 N/A ARG 135.A NE ASP 137.A OD1 no hydrogen 3.079 N/A ARG 135.A NH2 ASP 137.A OD2 no hydrogen 2.735 N/A LEU 136.A N THR 123.A OG1 no hydrogen 2.890 N/A ASP 137.A N ASP 153.A OD1 no hydrogen 2.801 N/A ARG 138.A N ASP 153.A OD1 no hydrogen 2.828 N/A ARG 138.A NE ASP 153.A OD2 no hydrogen 2.655 N/A ARG 138.A NH1 GLU 145.A OE1 no hydrogen 2.817 N/A ARG 138.A NH2 ASP 153.A OD2 no hydrogen 2.963 N/A GLU 140.A N ASN 110.A OD1 no hydrogen 2.893 N/A LEU 143.A N TRP 139.A O no hydrogen 2.963 N/A ASN 144.A N PRO 141.A O no hydrogen 3.235 N/A ASN 144.A ND2 GLU 140.A OE1 no hydrogen 2.785 N/A ASN 144.A ND2 PRO 141.A O no hydrogen 2.948 N/A GLU 145.A N GLU 142.A O no hydrogen 3.187 N/A ASP 150.A N ILE 147.A O no hydrogen 3.103 N/A ARG 152.A N ASP 150.A OD1 no hydrogen 2.869 N/A ARG 152.A NE ASP 150.A OD1 no hydrogen 3.445 N/A ARG 152.A NE ASP 150.A OD2 no hydrogen 3.014 N/A ARG 152.A NH2 ASP 150.A OD2 no hydrogen 3.041 N/A ASP 153.A N ASP 137.A OD1 no hydrogen 2.978 N/A THR 154.A OG1 GLU 151.A O no hydrogen 2.562 N/A THR 155.A N PHE 40.A O no hydrogen 3.038 N/A THR 155.A OG1 THR 134.A OG1 no hydrogen 2.734 N/A THR 155.A OG1 THR 156.A O no hydrogen 3.269 N/A THR 156.A OG1 PRO 36.A O no hydrogen 3.414 N/A ALA 158.A N PRO 36.A O no hydrogen 3.146 N/A ALA 159.A N THR 156.A OG1 no hydrogen 3.169 N/A MET 160.A N THR 156.A O no hydrogen 2.998 N/A ALA 161.A N PRO 157.A O no hydrogen 2.966 N/A THR 162.A N ALA 158.A O no hydrogen 3.014 N/A THR 162.A OG1 ALA 158.A O no hydrogen 2.810 N/A THR 162.A OG1 ALA 159.A O no hydrogen 3.009 N/A THR 163.A N ALA 159.A O no hydrogen 2.898 N/A THR 163.A OG1 ASP 131.A OD2 no hydrogen 2.640 N/A THR 163.A OG1 ALA 159.A O no hydrogen 3.060 N/A LEU 164.A N MET 160.A O no hydrogen 2.832 N/A ARG 165.A N ALA 161.A O no hydrogen 3.050 N/A ARG 165.A NE LEU 25.A O no hydrogen 2.820 N/A ARG 165.A NH2 ASN 26.A O no hydrogen 3.229 N/A LYS 166.A N THR 162.A O no hydrogen 2.983 N/A LYS 166.A NZ MET 129.A O no hydrogen 2.982 N/A LEU 167.A N THR 163.A O no hydrogen 2.984 N/A LEU 168.A N LEU 164.A O no hydrogen 2.932 N/A THR 169.A N ARG 165.A O no hydrogen 2.853 N/A THR 169.A OG1 ARG 165.A O no hydrogen 2.730 N/A GLY 170.A N LYS 166.A O no hydrogen 2.769 N/A THR 174.A N ASP 59.A OD2 no hydrogen 3.027 N/A THR 174.A OG1 ASP 59.A OD1 no hydrogen 2.755 N/A THR 174.A OG1 SER 177.A OG no hydrogen 3.266 N/A SER 177.A N THR 174.A OG1 no hydrogen 3.275 N/A SER 177.A OG ASP 59.A OD1 no hydrogen 2.638 N/A SER 177.A OG THR 174.A OG1 no hydrogen 3.266 N/A ARG 178.A N THR 174.A O no hydrogen 2.919 N/A ARG 178.A NE LEU 173.A O no hydrogen 2.922 N/A ARG 178.A NH2 LEU 173.A O no hydrogen 3.338 N/A GLN 179.A N LEU 175.A O no hydrogen 2.881 N/A GLN 179.A NE2 GLN 179.A O no hydrogen 3.436 N/A GLN 179.A NE2 ASP 183.A OD1 no hydrogen 2.981 N/A GLN 180.A N ALA 176.A O no hydrogen 3.007 N/A LEU 181.A N SER 177.A O no hydrogen 2.944 N/A ILE 182.A N ARG 178.A O no hydrogen 3.004 N/A ASP 183.A N GLN 179.A O no hydrogen 2.969 N/A TRP 184.A N GLN 180.A O no hydrogen 3.026 N/A MET 185.A N LEU 181.A O no hydrogen 3.223 N/A GLU 186.A N ILE 182.A O no hydrogen 2.804 N/A ALA 187.A N ASP 183.A O no hydrogen 3.119 N/A ALA 187.A N TRP 184.A O no hydrogen 3.211 N/A ASP 188.A N MET 185.A O no hydrogen 3.141 N/A LYS 189.A N THR 102.A O no hydrogen 2.882 N/A VAL 190.A N ASP 188.A OD1 no hydrogen 3.254 N/A LEU 194.A N ALA 191.A O no hydrogen 3.236 N/A ARG 196.A NE ASP 207.A OD1 no hydrogen 3.019 N/A ARG 196.A NE ASP 207.A OD2 no hydrogen 3.082 N/A ARG 196.A NH2 GLU 186.A O no hydrogen 2.989 N/A ARG 196.A NH2 ASP 207.A OD1 no hydrogen 2.873 N/A SER 197.A N LEU 194.A O no hydrogen 3.035 N/A SER 197.A OG PRO 193.A O no hydrogen 3.431 N/A SER 197.A OG LEU 194.A O no hydrogen 2.683 N/A ALA 198.A N LEU 195.A O no hydrogen 2.973 N/A LEU 199.A N ARG 196.A O no hydrogen 3.221 N/A TRP 203.A N PRO 200.A O no hydrogen 3.188 N/A PHE 204.A N GLY 224.A O no hydrogen 2.953 N/A ALA 206.A N ALA 222.A O no hydrogen 2.931 N/A ASP 207.A N MET 185.A O no hydrogen 3.189 N/A LYS 208.A N ILE 220.A O no hydrogen 2.898 N/A LYS 208.A NZ SER 104.A OG no hydrogen 2.979 N/A LYS 208.A NZ SER 209.A O no hydrogen 2.761 N/A GLY 210.A N GLY 218.A O no hydrogen 2.911 N/A GLY 212.A N SER 216.A O.A no hydrogen 2.832 N/A GLY 212.A N SER 216.A O.B no hydrogen 3.035 N/A GLU 213.A N ASN 144.A O no hydrogen 3.002 N/A SER 216.A N.A GLU 213.A O no hydrogen 3.249 N/A SER 216.A N.B GLU 213.A O no hydrogen 3.244 N/A SER 216.A OG.A GLU 213.A O no hydrogen 2.740 N/A SER 216.A OG.B GLU 213.A O no hydrogen 2.712 N/A SER 216.A OG.B THR 238.A OG1 no hydrogen 2.868 N/A ARG 217.A N THR 237.A O no hydrogen 3.054 N/A ARG 217.A NE ASN 248.A OD1 no hydrogen 2.743 N/A ARG 217.A NH1 GLY 210.A O no hydrogen 2.899 N/A ARG 217.A NH2 ASN 248.A OD1 no hydrogen 3.004 N/A GLY 218.A N GLY 210.A O no hydrogen 2.893 N/A ILE 219.A N ILE 235.A O no hydrogen 2.751 N/A ILE 220.A N LYS 208.A O no hydrogen 3.008 N/A ALA 221.A N VAL 233.A O no hydrogen 2.877 N/A ALA 222.A N ALA 206.A O no hydrogen 2.848 N/A LEU 223.A N ARG 231.A O no hydrogen 2.940 N/A GLY 224.A N PHE 204.A O no hydrogen 3.211 N/A GLY 227.A N GLY 202.A O no hydrogen 2.903 N/A LYS 228.A N PRO 225.A O no hydrogen 3.383 N/A LYS 228.A NZ ASP 226.A O no hydrogen 2.749 N/A SER 230.A N LEU 223.A O no hydrogen 2.994 N/A ARG 231.A N LEU 223.A O no hydrogen 3.033 N/A ARG 231.A NH1 GLU 22.A OE2 no hydrogen 2.941 N/A ARG 231.A NH2 TRP 262.A O no hydrogen 2.840 N/A ILE 232.A N.A LEU 23.A O no hydrogen 2.818 N/A ILE 232.A N.B LEU 23.A O no hydrogen 2.827 N/A VAL 233.A N ALA 221.A O no hydrogen 2.869 N/A VAL 234.A N ILE 21.A O no hydrogen 2.986 N/A ILE 235.A N ILE 219.A O no hydrogen 2.944 N/A TYR 236.A N GLY 19.A O no hydrogen 2.947 N/A TYR 236.A OH THR 45.A OG1 no hydrogen 2.847 N/A THR 237.A N ARG 217.A O no hydrogen 2.906 N/A THR 237.A OG1 ARG 17.A O no hydrogen 2.741 N/A THR 238.A OG1 SER 216.A OG.B no hydrogen 2.868 N/A GLY 239.A N ARG 214.A O no hydrogen 2.768 N/A SER 240.A OG LEU 14.A O no hydrogen 2.673 N/A ALA 242.A N SER 240.A OG no hydrogen 3.022 N/A GLU 246.A N THR 243.A OG1 no hydrogen 3.050 N/A ARG 247.A N THR 243.A O no hydrogen 3.038 N/A ARG 247.A NE ALA 242.A O no hydrogen 3.047 N/A ARG 247.A NE THR 243.A O no hydrogen 3.338 N/A ARG 247.A NH2 ALA 242.A O no hydrogen 3.383 N/A ASN 248.A N MET 244.A O no hydrogen 2.847 N/A ARG 249.A N ASP 245.A O no hydrogen 2.953 N/A ARG 249.A NE ASP 245.A OD2 no hydrogen 2.502 N/A ARG 249.A NH2 ASP 245.A OD2 no hydrogen 2.793 N/A GLN 250.A N GLU 246.A O no hydrogen 2.876 N/A GLN 250.A NE2 GLN 13.A OE1 no hydrogen 3.103 N/A GLN 250.A NE2 GLU 246.A OE2 no hydrogen 3.421 N/A ILE 251.A N ARG 247.A O no hydrogen 3.181 N/A ALA 252.A N ASN 248.A O no hydrogen 2.937 N/A GLU 253.A N ARG 249.A O no hydrogen 2.978 N/A ILE 254.A N GLN 250.A O no hydrogen 3.082 N/A GLY 255.A N ILE 251.A O no hydrogen 2.982 N/A ALA 256.A N ALA 252.A O no hydrogen 2.740 N/A SER 257.A N GLU 253.A O no hydrogen 3.140 N/A SER 257.A OG THR 3.A OG1 no hydrogen 2.716 N/A LEU 258.A N ILE 254.A O no hydrogen 3.066 N/A ILE 259.A N GLY 255.A O no hydrogen 3.095 N/A LYS 260.A N ALA 256.A O no hydrogen 2.906 N/A HIS 261.A N SER 257.A O no hydrogen 2.939 N/A TRP 262.A N ILE 259.A O no hydrogen 3.258 N/A