Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8ded_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 1.A N ILE 282.A O no hydrogen 2.608 N/A PHE 1.A N ASP 284.A OD1 no hydrogen 2.981 N/A HIS 3.A N ILE 280.A O no hydrogen 2.904 N/A THR 5.A N ILE 278.A O no hydrogen 2.886 N/A THR 6.A OG1 ILE 276.A O no hydrogen 3.401 N/A VAL 7.A N ILE 276.A O no hydrogen 2.880 N/A ASN 9.A N GLY 274.A O no hydrogen 2.959 N/A ASN 9.A ND2 TYR 273.A O no hydrogen 3.135 N/A VAL 10.A N PRO 8.A O no hydrogen 2.749 N/A GLY 12.A N VAL 33.A O no hydrogen 2.542 N/A TYR 15.A N GLU 30.A OE2 no hydrogen 2.738 N/A TYR 15.A N ILE 31.A O no hydrogen 2.930 N/A LYS 16.A NZ LEU 339.A O no hydrogen 3.266 N/A ALA 17.A N LEU 29.A O no hydrogen 2.911 N/A VAL 19.A N LEU 27.A O no hydrogen 2.951 N/A ALA 25.A N VAL 288.A O no hydrogen 3.076 N/A LEU 27.A N VAL 19.A O no hydrogen 2.913 N/A LEU 29.A N ALA 17.A O no hydrogen 2.877 N/A GLU 30.A N VAL 136.A O no hydrogen 2.938 N/A ILE 31.A N TYR 15.A O no hydrogen 2.971 N/A THR 32.A N ARG 134.A O no hydrogen 2.925 N/A THR 32.A OG1 ARG 134.A O no hydrogen 3.418 N/A SER 35.A N GLY 132.A O no hydrogen 3.348 N/A SER 35.A OG GLU 37.A OE1 no hydrogen 3.266 N/A GLU 37.A N LYS 130.A O no hydrogen 2.746 N/A LEU 38.A N ALA 268.A O no hydrogen 2.714 N/A THR 39.A N ALA 128.A O no hydrogen 2.822 N/A THR 39.A OG1 PRO 40.A O no hydrogen 3.527 N/A THR 39.A OG1 LEU 266.A O no hydrogen 3.081 N/A SER 41.A OG HIS 125.A ND1 no hydrogen 3.101 N/A ASN 43.A N LYS 123.A O no hydrogen 3.274 N/A GLU 45.A N ALA 121.A O no hydrogen 2.908 N/A TYR 46.A OH PRO 190.A O no hydrogen 2.279 N/A VAL 47.A N ALA 205.A O no hydrogen 2.848 N/A THR 48.A N ALA 119.A O no hydrogen 2.894 N/A THR 48.A OG1 ILE 203.A O no hydrogen 2.760 N/A CYS 49.A SG ARG 50.A O no hydrogen 3.536 N/A HIS 52.A N GLU 109.A O no hydrogen 2.841 N/A THR 53.A OG1 GLN 235.A OE1 no hydrogen 3.506 N/A GLN 59.A N LEU 103.A O no hydrogen 3.355 N/A LYS 61.A N THR 101.A O no hydrogen 2.926 N/A CYS 62.A SG GLN 93.A O no hydrogen 3.893 N/A CYS 68.A SG CYS 68.A O no hydrogen 2.967 N/A LYS 69.A NZ ALA 70.A O no hydrogen 3.167 N/A LYS 73.A N SER 71.A OG no hydrogen 3.285 N/A TYR 76.A N LYS 73.A O no hydrogen 3.192 N/A TYR 76.A OH GLU 105.A OE1 no hydrogen 2.257 N/A THR 77.A N ALA 106.A O no hydrogen 2.939 N/A THR 77.A OG1 ASP 75.A O no hydrogen 3.283 N/A CYS 78.A SG SER 104.A O no hydrogen 3.442 N/A ARG 79.A N SER 104.A O no hydrogen 2.900 N/A PHE 81.A N GLN 102.A O no hydrogen 2.924 N/A PHE 87.A N LYS 227.A O no hydrogen 3.194 N/A CYS 94.A SG PHE 95.A O no hydrogen 3.643 N/A CYS 94.A SG ASN 100.A OD1 no hydrogen 2.908 N/A SER 98.A OG GLU 99.A OE1 no hydrogen 2.958 N/A THR 101.A OG1 PHE 81.A O no hydrogen 2.975 N/A GLN 102.A N PHE 81.A O no hydrogen 2.901 N/A GLN 102.A NE2 HIS 230.A O no hydrogen 3.697 N/A LEU 103.A N GLN 59.A O no hydrogen 2.900 N/A SER 104.A N ARG 79.A O no hydrogen 2.921 N/A ALA 106.A N THR 77.A O no hydrogen 2.925 N/A TYR 107.A N VAL 54.A O no hydrogen 2.976 N/A VAL 108.A N ALA 74.A O no hydrogen 3.311 N/A GLU 109.A N HIS 52.A O no hydrogen 2.940 N/A ALA 111.A N ARG 50.A O no hydrogen 3.299 N/A CYS 114.A N ALA 111.A O no hydrogen 2.981 N/A CYS 114.A SG ARG 50.A O no hydrogen 3.386 N/A ALA 119.A N THR 48.A O no hydrogen 2.903 N/A VAL 120.A N ILE 179.A O no hydrogen 2.878 N/A ALA 121.A N TYR 46.A O no hydrogen 2.944 N/A LEU 122.A N VAL 177.A O no hydrogen 2.945 N/A LYS 123.A N ASN 43.A O no hydrogen 3.397 N/A LYS 123.A NZ GLU 45.A OE2 no hydrogen 2.784 N/A VAL 124.A N HIS 175.A O no hydrogen 2.700 N/A HIS 125.A ND1 SER 41.A OG no hydrogen 3.101 N/A ALA 128.A N THR 39.A O no hydrogen 2.849 N/A LYS 130.A N GLU 37.A O no hydrogen 2.976 N/A LYS 130.A NZ ASP 145.A OD2 no hydrogen 2.944 N/A VAL 131.A N THR 146.A O no hydrogen 2.907 N/A GLY 132.A N SER 35.A O no hydrogen 2.693 N/A LEU 133.A N LEU 144.A O no hydrogen 2.822 N/A ARG 134.A N THR 32.A O no hydrogen 2.963 N/A ILE 135.A N ALA 142.A O no hydrogen 2.935 N/A VAL 136.A N GLU 30.A O no hydrogen 2.921 N/A TYR 137.A N THR 140.A O no hydrogen 2.877 N/A TYR 137.A OH ASP 158.A OD2 no hydrogen 3.215 N/A GLY 138.A N ASN 28.A O no hydrogen 3.400 N/A GLY 138.A N ASN 28.A OD1 no hydrogen 2.627 N/A THR 140.A N TYR 137.A O no hydrogen 2.928 N/A THR 141.A OG1 ILE 135.A O no hydrogen 3.110 N/A ALA 142.A N ILE 135.A O no hydrogen 2.857 N/A LEU 144.A N LEU 133.A O no hydrogen 2.947 N/A THR 146.A N VAL 131.A O no hydrogen 2.924 N/A VAL 148.A N LEU 129.A O no hydrogen 3.207 N/A ASN 149.A ND2 THR 152.A OG1 no hydrogen 2.771 N/A GLY 150.A N ALA 163.A O no hydrogen 2.483 N/A VAL 151.A N ASN 149.A OD1 no hydrogen 2.873 N/A THR 152.A N ASN 149.A OD1 no hydrogen 2.863 N/A GLY 154.A N VAL 161.A O no hydrogen 2.916 N/A SER 155.A OG LEU 159.A O no hydrogen 3.540 N/A SER 156.A N LEU 159.A O no hydrogen 2.877 N/A SER 156.A OG HIS 143.A O no hydrogen 3.473 N/A ASP 158.A N SER 156.A O no hydrogen 2.477 N/A LEU 159.A N SER 156.A O no hydrogen 2.975 N/A LYS 160.A N ASP 281.A OD1 no hydrogen 2.815 N/A VAL 161.A N GLY 154.A O no hydrogen 2.912 N/A ILE 162.A N SER 279.A O no hydrogen 2.900 N/A GLY 164.A N PRO 277.A O no hydrogen 2.952 N/A SER 167.A N HIS 275.A O no hydrogen 2.876 N/A SER 167.A OG HIS 275.A O no hydrogen 3.471 N/A SER 171.A OG PHE 173.A O no hydrogen 3.334 N/A LYS 176.A NZ ASP 188.A OD1 no hydrogen 3.182 N/A VAL 177.A N LEU 122.A O no hydrogen 2.870 N/A VAL 178.A N TYR 185.A O no hydrogen 2.919 N/A ILE 179.A N VAL 120.A O no hydrogen 2.901 N/A ARG 180.A N LEU 183.A O no hydrogen 2.847 N/A LEU 183.A N ARG 180.A O no hydrogen 2.841 N/A TYR 185.A N VAL 178.A O no hydrogen 2.936 N/A ASN 186.A ND2 PRO 172.A O no hydrogen 3.646 N/A PHE 189.A N TYR 187.A O no hydrogen 2.914 N/A TYR 192.A OH ASP 212.A OD2 no hydrogen 3.358 N/A GLY 193.A N GLN 204.A OE1 no hydrogen 2.567 N/A ALA 194.A N GLU 191.A O no hydrogen 3.012 N/A LYS 196.A NZ ALA 194.A O no hydrogen 2.605 N/A ASP 202.A N ALA 199.A O no hydrogen 3.060 N/A GLN 204.A N VAL 214.A O no hydrogen 2.741 N/A GLN 204.A NE2 GLU 191.A O no hydrogen 3.380 N/A GLN 204.A NE2 GLY 201.A O no hydrogen 3.148 N/A SER 206.A OG SER 207.A OG no hydrogen 3.421 N/A SER 207.A OG SER 206.A OG no hydrogen 3.421 N/A ALA 210.A N SER 207.A O no hydrogen 3.197 N/A VAL 214.A N GLN 204.A O no hydrogen 3.035 N/A ARG 216.A N ASP 202.A O no hydrogen 3.011 N/A THR 217.A N ASP 75.A OD2 no hydrogen 2.521 N/A THR 217.A OG1 ASP 75.A OD2 no hydrogen 2.522 N/A ARG 220.A N THR 234.A O no hydrogen 2.921 N/A LEU 222.A N PRO 232.A O no hydrogen 2.882 N/A ILE 229.A N PHE 87.A O no hydrogen 2.473 N/A HIS 230.A ND1 ASN 228.A O no hydrogen 2.874 N/A THR 234.A N ARG 220.A O no hydrogen 2.926 N/A ALA 236.A N THR 217.A O no hydrogen 3.335 N/A GLY 239.A N ASP 202.A OD2 no hydrogen 2.470 N/A TYR 240.A OH ASP 117.A OD1 no hydrogen 2.327 N/A MET 242.A N SER 238.A O no hydrogen 3.095 N/A TRP 243.A N GLY 239.A O no hydrogen 2.864 N/A LYS 244.A N TYR 240.A O no hydrogen 2.860 N/A ASN 245.A N GLU 241.A O no hydrogen 2.912 N/A ASN 246.A N MET 242.A O no hydrogen 3.208 N/A SER 247.A OG GLY 248.A O no hydrogen 3.344 N/A ARG 249.A NE GLU 253.A OE1 no hydrogen 3.470 N/A LEU 251.A N VAL 184.A O no hydrogen 2.772 N/A GLU 253.A N PRO 250.A O no hydrogen 3.388 N/A THR 254.A N LEU 251.A O no hydrogen 3.245 N/A THR 254.A OG1 ARG 249.A O no hydrogen 3.427 N/A THR 254.A OG1 PRO 250.A O no hydrogen 2.777 N/A ALA 255.A N LEU 251.A O no hydrogen 3.239 N/A CYS 259.A SG PRO 256.A O no hydrogen 3.673 N/A LYS 260.A N SER 269.A O no hydrogen 2.949 N/A GLU 262.A N ARG 267.A O no hydrogen 2.918 N/A ARG 267.A N GLU 262.A O no hydrogen 2.886 N/A ARG 267.A NH1 PRO 265.A O no hydrogen 3.293 N/A ALA 268.A N LEU 38.A O no hydrogen 2.856 N/A SER 269.A N LYS 260.A O no hydrogen 2.837 N/A ASN 270.A N SER 36.A O no hydrogen 2.858 N/A CYS 271.A N SER 36.A OG no hydrogen 2.910 N/A HIS 275.A N SER 167.A OG no hydrogen 2.677 N/A ILE 276.A N VAL 7.A O no hydrogen 2.902 N/A ILE 278.A N THR 5.A O no hydrogen 2.901 N/A SER 279.A N ILE 162.A O no hydrogen 2.968 N/A ILE 280.A N HIS 3.A O no hydrogen 2.889 N/A ASP 281.A N LYS 160.A O no hydrogen 2.957 N/A ALA 286.A N PRO 283.A O no hydrogen 3.055 N/A PHE 287.A N ASP 284.A O no hydrogen 3.164 N/A SER 290.A OG GLY 23.A O no hydrogen 3.030 N/A GLU 292.A N ARG 289.A O no hydrogen 2.890 N/A GLU 298.A N LYS 321.A O no hydrogen 2.942 N/A SER 300.A N GLN 319.A O no hydrogen 2.914 N/A SER 300.A OG GLN 319.A OE1 no hydrogen 3.508 N/A THR 302.A N THR 317.A O no hydrogen 2.959 N/A THR 302.A OG1 THR 317.A O no hydrogen 3.415 N/A ALA 304.A N SER 315.A O no hydrogen 2.897 N/A CYS 306.A SG GLU 379.A O no hydrogen 3.417 N/A ILE 307.A N GLY 313.A O no hydrogen 3.210 N/A TYR 308.A N LYS 381.A O no hydrogen 3.398 N/A SER 309.A OG ASP 311.A O no hydrogen 3.415 N/A SER 309.A OG ASP 311.A OD1 no hydrogen 2.105 N/A GLY 313.A N ASP 311.A O no hydrogen 2.745 N/A GLY 314.A N PHE 356.A O no hydrogen 2.918 N/A LEU 316.A N LEU 354.A O no hydrogen 2.937 N/A THR 317.A N THR 302.A O no hydrogen 2.923 N/A THR 317.A OG1 ILE 352.A O no hydrogen 3.269 N/A LEU 318.A N ILE 352.A O no hydrogen 2.881 N/A GLN 319.A N SER 300.A O no hydrogen 2.920 N/A TYR 320.A N GLY 350.A O no hydrogen 2.896 N/A TYR 320.A OH THR 347.A OG1 no hydrogen 2.449 N/A LYS 321.A N GLU 298.A O no hydrogen 2.873 N/A LYS 321.A NZ GLN 319.A OE1 no hydrogen 2.580 N/A ALA 322.A N ALA 348.A O no hydrogen 2.357 N/A ARG 324.A NE ASP 323.A OD1 no hydrogen 3.550 N/A ARG 324.A NH1 SER 291.A O no hydrogen 3.188 N/A ARG 324.A NH2 SER 291.A O no hydrogen 3.519 N/A GLY 326.A N VAL 346.A O no hydrogen 2.931 N/A CYS 328.A SG PRO 294.A O no hydrogen 3.792 N/A VAL 330.A N ALA 342.A O no hydrogen 2.617 N/A HIS 331.A N SER 368.A O no hydrogen 2.933 N/A HIS 331.A ND1 HIS 333.A ND1 no hydrogen 3.123 N/A SER 332.A OG SER 334.A OG no hydrogen 3.244 N/A SER 332.A OG ALA 337.A O no hydrogen 3.115 N/A HIS 333.A N ILE 366.A O no hydrogen 2.680 N/A HIS 333.A ND1 HIS 331.A ND1 no hydrogen 3.123 N/A SER 334.A OG SER 332.A OG no hydrogen 3.244 N/A VAL 338.A N SER 357.A O no hydrogen 2.916 N/A LYS 340.A N HIS 355.A O no hydrogen 2.649 N/A THR 344.A N CYS 328.A O no hydrogen 2.914 N/A VAL 346.A N GLY 326.A O no hydrogen 2.871 N/A THR 347.A N TYR 320.A OH no hydrogen 3.202 N/A THR 347.A OG1 TYR 320.A OH no hydrogen 2.449 N/A THR 347.A OG1 VAL 349.A O no hydrogen 2.803 N/A GLY 350.A N TYR 320.A O no hydrogen 2.935 N/A ILE 352.A N LEU 318.A O no hydrogen 2.957 N/A THR 353.A OG1 LEU 316.A O no hydrogen 3.006 N/A LEU 354.A N LEU 316.A O no hydrogen 2.877 N/A HIS 355.A N GLU 341.A OE1 no hydrogen 3.033 N/A PHE 356.A N GLY 314.A O no hydrogen 2.862 N/A SER 357.A N VAL 338.A O no hydrogen 2.876 N/A SER 357.A OG SER 309.A O no hydrogen 2.975 N/A SER 357.A OG ASP 311.A O no hydrogen 2.604 N/A THR 358.A OG1 THR 336.A O no hydrogen 2.385 N/A SER 360.A N THR 358.A OG1 no hydrogen 3.395 N/A SER 360.A OG GLN 362.A O no hydrogen 2.904 N/A SER 360.A OG GLN 362.A OE1 no hydrogen 3.165 N/A GLN 362.A N SER 360.A OG no hydrogen 3.250 N/A ALA 363.A N ALA 378.A O no hydrogen 2.891 N/A PHE 365.A N CYS 376.A O no hydrogen 2.984 N/A VAL 367.A N THR 374.A O no hydrogen 2.891 N/A SER 368.A N HIS 331.A O no hydrogen 2.863 N/A SER 368.A OG HIS 331.A O no hydrogen 3.556 N/A LEU 369.A N LYS 372.A O no hydrogen 2.940 N/A CYS 370.A N PRO 329.A O no hydrogen 3.264 N/A CYS 370.A SG SER 293.A OG no hydrogen 3.493 N/A CYS 370.A SG PRO 294.A O no hydrogen 3.437 N/A LYS 372.A NZ ILE 296.A O no hydrogen 2.718 N/A LYS 373.A NZ GLY 371.A O no hydrogen 2.836 N/A THR 374.A N VAL 367.A O no hydrogen 2.903 N/A THR 374.A OG1 LYS 373.A O no hydrogen 2.578 N/A THR 375.A OG1 PHE 365.A O no hydrogen 3.566 N/A THR 375.A OG1 ASN 377.A OD1 no hydrogen 3.069 N/A CYS 376.A N PHE 365.A O no hydrogen 2.837 N/A ALA 378.A N ALA 363.A O no hydrogen 2.869 N/A CYS 380.A N PRO 361.A O no hydrogen 2.537 N/A LYS 381.A N CYS 306.A O no hydrogen 3.261 N/A LYS 381.A NZ PRO 382.A O no hydrogen 3.220 N/A HIS 386.A N ASP 385.A OD1 no hydrogen 2.896 N/A LYS 393.A NZ ALA 310.A O no hydrogen 3.290 N/A LYS 393.A NZ GLU 390.A OE1 no hydrogen 2.681 N/A