Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8dee_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 1.A N ILE 282.A O no hydrogen 2.999 N/A PHE 1.A N ASP 284.A OD1 no hydrogen 2.618 N/A HIS 3.A N ILE 280.A O no hydrogen 2.903 N/A THR 5.A N ILE 278.A O no hydrogen 2.926 N/A VAL 7.A N ILE 276.A O no hydrogen 2.904 N/A ASN 9.A N GLY 274.A O no hydrogen 3.038 N/A ASN 9.A ND2 CYS 271.A O no hydrogen 3.189 N/A ASN 9.A ND2 TYR 273.A O no hydrogen 2.588 N/A GLY 12.A N VAL 33.A O no hydrogen 3.276 N/A ILE 13.A N VAL 10.A O no hydrogen 3.407 N/A TYR 15.A N ILE 31.A O no hydrogen 2.883 N/A TYR 15.A OH THR 5.A OG1 no hydrogen 3.411 N/A LYS 16.A NZ LYS 340.A O no hydrogen 3.557 N/A ALA 17.A N LEU 29.A O no hydrogen 2.896 N/A VAL 19.A N LEU 27.A O no hydrogen 2.894 N/A ALA 25.A N VAL 288.A O no hydrogen 3.244 N/A LEU 27.A N VAL 19.A O no hydrogen 2.926 N/A LEU 29.A N ALA 17.A O no hydrogen 2.917 N/A GLU 30.A N VAL 136.A O no hydrogen 2.977 N/A ILE 31.A N TYR 15.A O no hydrogen 2.920 N/A THR 32.A N ARG 134.A O no hydrogen 2.908 N/A THR 32.A OG1 ARG 134.A O no hydrogen 3.289 N/A VAL 34.A N GLY 132.A O no hydrogen 2.894 N/A SER 35.A N GLY 132.A O no hydrogen 3.424 N/A GLU 37.A N LYS 130.A O no hydrogen 2.623 N/A LEU 38.A N ALA 268.A O no hydrogen 2.907 N/A THR 39.A N ALA 128.A O no hydrogen 3.248 N/A THR 39.A OG1 PRO 40.A O no hydrogen 3.428 N/A THR 39.A OG1 LEU 266.A O no hydrogen 3.343 N/A LYS 44.A NZ SER 206.A O no hydrogen 2.385 N/A GLU 45.A N ALA 121.A O no hydrogen 2.960 N/A TYR 46.A OH PRO 190.A O no hydrogen 2.714 N/A VAL 47.A N ALA 205.A O no hydrogen 2.951 N/A THR 48.A N ALA 119.A O no hydrogen 2.906 N/A THR 48.A OG1 ILE 203.A O no hydrogen 3.119 N/A CYS 49.A SG ARG 50.A O no hydrogen 3.392 N/A HIS 52.A N GLU 109.A O no hydrogen 2.874 N/A THR 53.A OG1 GLN 235.A OE1 no hydrogen 2.354 N/A CYS 62.A SG GLN 93.A O no hydrogen 3.893 N/A CYS 63.A SG GLU 99.A OE2 no hydrogen 3.280 N/A SER 72.A OG SER 72.A O no hydrogen 2.200 N/A TYR 76.A OH GLU 105.A OE1 no hydrogen 2.654 N/A THR 77.A N ALA 106.A O no hydrogen 2.914 N/A THR 77.A OG1 ASP 75.A O no hydrogen 3.468 N/A CYS 78.A SG ARG 79.A O no hydrogen 4.048 N/A CYS 78.A SG SER 104.A O no hydrogen 3.999 N/A ARG 79.A N SER 104.A O no hydrogen 2.907 N/A PHE 81.A N GLN 102.A O no hydrogen 2.884 N/A TYR 85.A N ASN 100.A OD1 no hydrogen 3.141 N/A CYS 94.A SG CYS 62.A O no hydrogen 3.819 N/A CYS 94.A SG GLN 93.A O no hydrogen 3.380 N/A THR 101.A OG1 PHE 81.A O no hydrogen 2.515 N/A THR 101.A OG1 GLN 102.A O no hydrogen 3.379 N/A GLN 102.A N PHE 81.A O no hydrogen 2.921 N/A LEU 103.A N GLN 59.A O no hydrogen 2.890 N/A SER 104.A N ARG 79.A O no hydrogen 2.894 N/A SER 104.A OG GLN 102.A OE1 no hydrogen 2.857 N/A ALA 106.A N THR 77.A O no hydrogen 2.934 N/A TYR 107.A N VAL 54.A O no hydrogen 2.991 N/A VAL 108.A N ALA 74.A O no hydrogen 3.165 N/A GLU 109.A N HIS 52.A O no hydrogen 2.911 N/A ALA 111.A N ARG 50.A O no hydrogen 3.365 N/A CYS 114.A N ALA 111.A O no hydrogen 3.099 N/A CYS 114.A SG ARG 50.A O no hydrogen 3.206 N/A ASP 117.A N ASP 113.A O no hydrogen 3.454 N/A ALA 119.A N THR 48.A O no hydrogen 2.877 N/A VAL 120.A N ILE 179.A O no hydrogen 2.883 N/A ALA 121.A N TYR 46.A O no hydrogen 2.951 N/A LEU 122.A N VAL 177.A O no hydrogen 2.904 N/A LYS 123.A NZ GLU 191.A OE1 no hydrogen 2.948 N/A LYS 123.A NZ GLU 191.A OE2 no hydrogen 3.442 N/A VAL 124.A N HIS 175.A O no hydrogen 2.926 N/A ALA 128.A N THR 39.A O no hydrogen 3.295 N/A LYS 130.A N GLU 37.A O no hydrogen 2.945 N/A VAL 131.A N THR 146.A O no hydrogen 2.912 N/A GLY 132.A N SER 35.A O no hydrogen 2.653 N/A LEU 133.A N LEU 144.A O no hydrogen 2.851 N/A ARG 134.A N THR 32.A O no hydrogen 2.932 N/A ARG 134.A NH1 GLU 30.A OE2 no hydrogen 3.249 N/A ILE 135.A N ALA 142.A O no hydrogen 2.918 N/A VAL 136.A N GLU 30.A O no hydrogen 2.912 N/A TYR 137.A N THR 140.A O no hydrogen 2.924 N/A GLY 138.A N ASN 28.A OD1 no hydrogen 2.928 N/A THR 140.A N TYR 137.A O no hydrogen 2.927 N/A ALA 142.A N ILE 135.A O no hydrogen 2.883 N/A LEU 144.A N LEU 133.A O no hydrogen 2.951 N/A THR 146.A N VAL 131.A O no hydrogen 2.920 N/A THR 146.A OG1 PHE 147.A O no hydrogen 3.227 N/A VAL 148.A N LEU 129.A O no hydrogen 2.870 N/A ASN 149.A ND2 THR 152.A OG1 no hydrogen 2.661 N/A GLY 150.A N ALA 163.A O no hydrogen 2.648 N/A VAL 151.A N ASN 149.A OD1 no hydrogen 2.895 N/A THR 152.A N ASN 149.A OD1 no hydrogen 2.895 N/A GLY 154.A N VAL 161.A O no hydrogen 2.868 N/A SER 156.A N LEU 159.A O no hydrogen 2.900 N/A ARG 157.A NH1 SER 156.A O no hydrogen 2.957 N/A ASP 158.A N SER 156.A O no hydrogen 2.489 N/A LEU 159.A N SER 156.A O no hydrogen 2.974 N/A VAL 161.A N GLY 154.A O no hydrogen 2.938 N/A ILE 162.A N SER 279.A O no hydrogen 2.895 N/A GLY 164.A N PRO 277.A O no hydrogen 2.565 N/A SER 167.A N HIS 275.A O no hydrogen 3.211 N/A LYS 176.A NZ PHE 189.A O no hydrogen 3.115 N/A LYS 176.A NZ GLU 191.A OE2 no hydrogen 2.844 N/A VAL 177.A N LEU 122.A O no hydrogen 2.891 N/A VAL 178.A N TYR 185.A O no hydrogen 2.897 N/A ILE 179.A N VAL 120.A O no hydrogen 2.927 N/A ARG 180.A N LEU 183.A O no hydrogen 2.889 N/A ARG 180.A NH1 TYR 240.A OH no hydrogen 3.107 N/A LEU 183.A N ARG 180.A O no hydrogen 2.908 N/A TYR 185.A N VAL 178.A O no hydrogen 2.913 N/A PHE 189.A N TYR 187.A O no hydrogen 2.882 N/A GLY 193.A N GLN 204.A OE1 no hydrogen 2.881 N/A ALA 194.A N GLU 191.A O no hydrogen 3.004 N/A GLN 204.A N VAL 214.A O no hydrogen 2.952 N/A GLN 204.A NE2 GLU 191.A O no hydrogen 3.446 N/A GLN 204.A NE2 GLY 201.A O no hydrogen 2.923 N/A SER 206.A OG ASP 212.A OD1 no hydrogen 3.483 N/A SER 207.A OG SER 206.A O no hydrogen 2.712 N/A ALA 210.A N SER 207.A O no hydrogen 3.246 N/A VAL 214.A N GLN 204.A O no hydrogen 3.187 N/A ARG 216.A N ASP 202.A O no hydrogen 3.038 N/A ARG 216.A NE MET 195.A O no hydrogen 2.889 N/A THR 217.A N ASP 75.A OD2 no hydrogen 2.530 N/A THR 217.A OG1 ASP 75.A OD2 no hydrogen 2.833 N/A ARG 220.A N THR 234.A O no hydrogen 3.128 N/A ILE 229.A N PHE 87.A O no hydrogen 2.955 N/A THR 234.A N ARG 220.A O no hydrogen 3.186 N/A GLN 235.A NE2 THR 217.A OG1 no hydrogen 2.518 N/A ALA 236.A N THR 217.A O no hydrogen 3.344 N/A GLY 239.A N ASP 202.A OD2 no hydrogen 2.724 N/A TYR 240.A OH ASP 117.A OD1 no hydrogen 2.655 N/A MET 242.A N SER 238.A O no hydrogen 3.260 N/A TRP 243.A N GLY 239.A O no hydrogen 2.911 N/A LYS 244.A N TYR 240.A O no hydrogen 2.885 N/A LYS 244.A NZ GLU 241.A OE2 no hydrogen 2.663 N/A ASN 245.A N GLU 241.A O no hydrogen 2.897 N/A ASN 245.A ND2 ASN 246.A OD1 no hydrogen 3.129 N/A ASN 246.A N MET 242.A O no hydrogen 3.086 N/A SER 247.A OG GLY 248.A O no hydrogen 2.969 N/A ARG 249.A NE GLU 253.A OE1 no hydrogen 2.878 N/A ARG 249.A NH2 GLU 253.A OE1 no hydrogen 3.112 N/A ARG 249.A NH2 GLU 253.A OE2 no hydrogen 3.359 N/A LEU 251.A N VAL 184.A O no hydrogen 2.546 N/A GLN 252.A NE2 GLY 182.A O no hydrogen 3.348 N/A GLU 253.A N PRO 250.A O no hydrogen 3.348 N/A THR 254.A N LEU 251.A O no hydrogen 3.347 N/A THR 254.A OG1 PRO 250.A O no hydrogen 2.977 N/A ALA 255.A N LEU 251.A O no hydrogen 3.090 N/A LYS 260.A N SER 269.A O no hydrogen 2.962 N/A GLU 262.A N ARG 267.A O no hydrogen 2.900 N/A ARG 267.A N GLU 262.A O no hydrogen 2.905 N/A ARG 267.A NE GLU 262.A OE1 no hydrogen 3.195 N/A ALA 268.A N LEU 38.A O no hydrogen 2.830 N/A SER 269.A N LYS 260.A O no hydrogen 2.841 N/A SER 269.A OG GLU 262.A OE1 no hydrogen 2.756 N/A ASN 270.A N SER 36.A O no hydrogen 3.246 N/A CYS 271.A N SER 36.A OG no hydrogen 3.162 N/A ALA 272.A N PHE 257.A O no hydrogen 3.383 N/A HIS 275.A N SER 167.A OG no hydrogen 3.346 N/A ILE 276.A N VAL 7.A O no hydrogen 2.871 N/A ILE 278.A N THR 5.A O no hydrogen 2.875 N/A SER 279.A N ILE 162.A O no hydrogen 2.894 N/A ILE 280.A N HIS 3.A O no hydrogen 2.880 N/A ASP 281.A N LYS 160.A O no hydrogen 2.926 N/A PHE 287.A N ASP 284.A O no hydrogen 3.233 N/A GLU 292.A N ARG 289.A O no hydrogen 3.287 N/A SER 293.A N ARG 289.A O no hydrogen 3.240 N/A LEU 297.A N LYS 321.A O no hydrogen 2.600 N/A GLU 298.A N LYS 321.A O no hydrogen 2.979 N/A SER 300.A N GLN 319.A O no hydrogen 2.900 N/A THR 302.A N THR 317.A O no hydrogen 2.916 N/A THR 302.A OG1 THR 317.A O no hydrogen 3.527 N/A THR 302.A OG1 THR 317.A OG1 no hydrogen 2.359 N/A ALA 304.A N SER 315.A O no hydrogen 3.108 N/A SER 309.A OG ASP 311.A OD1 no hydrogen 2.677 N/A GLY 313.A N ASP 311.A O no hydrogen 2.911 N/A SER 315.A OG LEU 354.A O no hydrogen 3.564 N/A LEU 316.A N LEU 354.A O no hydrogen 2.921 N/A THR 317.A N THR 302.A O no hydrogen 2.861 N/A THR 317.A OG1 THR 302.A O no hydrogen 2.632 N/A THR 317.A OG1 THR 302.A OG1 no hydrogen 2.359 N/A LEU 318.A N ILE 352.A O no hydrogen 2.884 N/A GLN 319.A N SER 300.A O no hydrogen 2.901 N/A TYR 320.A N GLY 350.A O no hydrogen 2.890 N/A TYR 320.A OH THR 347.A OG1 no hydrogen 2.686 N/A LYS 321.A N GLU 298.A O no hydrogen 2.844 N/A ALA 322.A N ALA 348.A O no hydrogen 2.586 N/A GLY 326.A N VAL 346.A O no hydrogen 2.910 N/A CYS 328.A SG PRO 294.A O no hydrogen 3.246 N/A VAL 330.A N ALA 342.A O no hydrogen 2.892 N/A HIS 331.A N SER 368.A O no hydrogen 2.926 N/A HIS 331.A ND1 HIS 333.A ND1 no hydrogen 3.173 N/A SER 332.A OG ALA 337.A O no hydrogen 3.417 N/A HIS 333.A N ILE 366.A O no hydrogen 2.776 N/A SER 334.A OG THR 336.A OG1 no hydrogen 3.088 N/A THR 335.A OG1 GLU 397.A OE1 no hydrogen 3.378 N/A THR 335.A OG1 GLU 397.A OE2 no hydrogen 3.456 N/A THR 336.A N SER 334.A OG no hydrogen 3.223 N/A THR 336.A OG1 SER 334.A OG no hydrogen 3.088 N/A VAL 338.A N SER 357.A O no hydrogen 2.919 N/A LYS 340.A N HIS 355.A O no hydrogen 3.199 N/A GLU 341.A N GLU 341.A OE2 no hydrogen 2.445 N/A THR 344.A N CYS 328.A O no hydrogen 2.889 N/A VAL 346.A N GLY 326.A O no hydrogen 2.885 N/A THR 347.A N TYR 320.A OH no hydrogen 2.931 N/A THR 347.A OG1 TYR 320.A OH no hydrogen 2.686 N/A THR 347.A OG1 VAL 349.A O no hydrogen 3.248 N/A GLY 350.A N TYR 320.A O no hydrogen 2.932 N/A ILE 352.A N LEU 318.A O no hydrogen 2.942 N/A LEU 354.A N LEU 316.A O no hydrogen 2.905 N/A PHE 356.A N GLY 314.A O no hydrogen 2.854 N/A SER 357.A N VAL 338.A O no hydrogen 2.902 N/A SER 357.A OG SER 309.A O no hydrogen 2.977 N/A THR 358.A OG1 THR 336.A O no hydrogen 2.932 N/A THR 358.A OG1 SER 360.A OG no hydrogen 2.950 N/A SER 359.A N THR 336.A O no hydrogen 3.288 N/A SER 360.A N THR 358.A OG1 no hydrogen 3.025 N/A SER 360.A OG THR 358.A OG1 no hydrogen 2.950 N/A SER 360.A OG GLN 362.A O no hydrogen 2.630 N/A PHE 365.A N CYS 376.A O no hydrogen 3.021 N/A VAL 367.A N THR 374.A O no hydrogen 2.874 N/A SER 368.A N HIS 331.A O no hydrogen 2.871 N/A LEU 369.A N LYS 372.A O no hydrogen 2.892 N/A CYS 370.A N PRO 329.A O no hydrogen 3.361 N/A CYS 370.A SG PRO 294.A O no hydrogen 3.419 N/A LYS 372.A N LEU 369.A O no hydrogen 2.933 N/A LYS 372.A NZ ILE 296.A O no hydrogen 3.009 N/A LYS 372.A NZ LEU 297.A O no hydrogen 2.457 N/A THR 374.A N VAL 367.A O no hydrogen 2.931 N/A CYS 376.A N PHE 365.A O no hydrogen 2.838 N/A ALA 378.A N ALA 363.A O no hydrogen 2.690 N/A CYS 380.A N PRO 361.A O no hydrogen 2.738 N/A LYS 381.A N CYS 306.A O no hydrogen 3.333 N/A LYS 393.A NZ GLU 390.A OE1 no hydrogen 3.236 N/A SER 403.A OG SER 406.A OG no hydrogen 2.739 N/A SER 406.A OG SER 403.A O no hydrogen 2.567 N/A SER 406.A OG SER 403.A OG no hydrogen 2.739 N/A TRP 407.A N SER 403.A O no hydrogen 2.814 N/A ASN 408.A N LYS 404.A O no hydrogen 2.847 N/A TRP 409.A N THR 405.A O no hydrogen 2.940 N/A LEU 410.A N SER 406.A O no hydrogen 2.904 N/A LEU 411.A N TRP 407.A O no hydrogen 2.875 N/A ALA 412.A N ASN 408.A O no hydrogen 2.865 N/A LEU 413.A N TRP 409.A O no hydrogen 2.932 N/A PHE 414.A N LEU 410.A O no hydrogen 2.949 N/A GLY 415.A N LEU 411.A O no hydrogen 2.804 N/A GLY 416.A N ALA 412.A O no hydrogen 2.920 N/A SER 418.A N PHE 414.A O no hydrogen 2.986 N/A SER 418.A OG GLY 415.A O no hydrogen 2.892 N/A SER 419.A N GLY 415.A O no hydrogen 2.830 N/A SER 419.A OG GLY 415.A O no hydrogen 3.066 N/A SER 419.A OG GLY 416.A O no hydrogen 2.967 N/A LEU 420.A N GLY 416.A O no hydrogen 2.893 N/A ILE 421.A N ALA 417.A O no hydrogen 2.939 N/A VAL 422.A N SER 418.A O no hydrogen 2.957 N/A VAL 423.A N SER 419.A O no hydrogen 2.833 N/A GLY 424.A N LEU 420.A O no hydrogen 2.873 N/A LEU 425.A N ILE 421.A O no hydrogen 2.943 N/A ILE 426.A N VAL 422.A O no hydrogen 2.911 N/A VAL 427.A N VAL 423.A O no hydrogen 2.833 N/A LEU 428.A N GLY 424.A O no hydrogen 2.925 N/A VAL 429.A N LEU 425.A O no hydrogen 2.939 N/A CYS 430.A N ILE 426.A O no hydrogen 2.865 N/A CYS 430.A SG ILE 426.A O no hydrogen 3.270 N/A SER 431.A N VAL 427.A O no hydrogen 2.878 N/A SER 431.A OG VAL 427.A O no hydrogen 3.423 N/A SER 431.A OG LEU 428.A O no hydrogen 2.729 N/A SER 432.A N LEU 428.A O no hydrogen 2.949 N/A MET 433.A N VAL 429.A O no hydrogen 2.905 N/A LEU 434.A N CYS 430.A O no hydrogen 2.866 N/A ILE 435.A N SER 431.A O no hydrogen 2.911 N/A ASN 436.A N SER 432.A O no hydrogen 2.928 N/A THR 437.A N MET 433.A O no hydrogen 2.877 N/A THR 437.A OG1 MET 433.A O no hydrogen 3.174 N/A ARG 438.A N LEU 434.A O no hydrogen 2.958 N/A ARG 439.A N ASN 436.A O no hydrogen 3.454 N/A