Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8dic_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 4.A N GLN 293.A OE1 no hydrogen 2.918 N/A LYS 5.A NZ GLU 282.A OE2 no hydrogen 3.435 N/A PHE 8.A N SER 110.A OG no hydrogen 2.660 N/A SER 10.A OG GLU 14.A OE2 no hydrogen 2.648 N/A GLU 14.A N SER 10.A O no hydrogen 2.839 N/A GLY 15.A N GLY 11.A O no hydrogen 3.303 N/A CYS 16.A N VAL 13.A O no hydrogen 3.108 N/A CYS 16.A SG LYS 12.A O no hydrogen 3.482 N/A MET 17.A N GLU 14.A O no hydrogen 3.274 N/A VAL 18.A N GLY 29.A O no hydrogen 2.964 N/A GLN 19.A N GLN 66.A O no hydrogen 2.830 N/A GLN 19.A NE2 ASN 116.A OD1 no hydrogen 3.308 N/A VAL 20.A N LEU 27.A O no hydrogen 2.778 N/A THR 21.A N LEU 64.A O no hydrogen 2.830 N/A THR 21.A OG1 THR 26.A OG1 no hydrogen 2.734 N/A CYS 22.A N THR 25.A O no hydrogen 2.844 N/A CYS 22.A SG ASN 62.A O no hydrogen 3.851 N/A THR 25.A N CYS 22.A O no hydrogen 3.036 N/A THR 25.A OG1 CYS 44.A O no hydrogen 3.467 N/A THR 26.A OG1 THR 21.A OG1 no hydrogen 2.734 N/A LEU 27.A N VAL 20.A O no hydrogen 2.900 N/A ASN 28.A N CYS 142.A O no hydrogen 3.054 N/A ASN 28.A ND2 CYS 114.A O no hydrogen 2.925 N/A ASN 28.A ND2 SER 141.A O no hydrogen 3.449 N/A ASN 28.A ND2 CYS 142.A O no hydrogen 3.125 N/A GLY 29.A N VAL 18.A O no hydrogen 2.746 N/A LEU 30.A N TYR 37.A O no hydrogen 2.669 N/A TRP 31.A N CYS 16.A O no hydrogen 2.774 N/A LEU 32.A N VAL 35.A O no hydrogen 2.992 N/A ASP 33.A N THR 95.A OG1 no hydrogen 2.787 N/A VAL 35.A N LEU 32.A O no hydrogen 3.181 N/A VAL 36.A N LEU 86.A O no hydrogen 2.810 N/A TYR 37.A N LEU 30.A O no hydrogen 2.684 N/A CYS 38.A N LEU 84.A O no hydrogen 3.253 N/A CYS 38.A SG PRO 39.A O no hydrogen 3.446 N/A ARG 40.A N CYS 82.A O no hydrogen 2.977 N/A ARG 40.A NE ASP 182.A OD2 no hydrogen 2.665 N/A ARG 40.A NH2 ASP 182.A OD1 no hydrogen 3.138 N/A HIS 41.A NE2 HIS 160.A O no hydrogen 2.853 N/A VAL 42.A N PRO 39.A O no hydrogen 3.384 N/A ILE 43.A N ARG 40.A O no hydrogen 3.228 N/A CYS 44.A N HIS 41.A O no hydrogen 2.937 N/A CYS 44.A SG TYR 51.A OH no hydrogen 3.698 N/A TYR 51.A OH ASP 182.A O no hydrogen 2.655 N/A ASP 53.A N ASN 50.A OD1 no hydrogen 3.378 N/A LEU 54.A N ASN 50.A O no hydrogen 2.948 N/A LEU 55.A N TYR 51.A O no hydrogen 2.905 N/A ILE 56.A N GLU 52.A O no hydrogen 3.069 N/A LYS 58.A N LEU 55.A O no hydrogen 3.048 N/A LYS 58.A NZ LEU 54.A O no hydrogen 3.502 N/A SER 59.A N ASN 62.A OD1 no hydrogen 2.787 N/A ASN 62.A N SER 59.A O no hydrogen 2.876 N/A PHE 63.A N ASN 60.A O no hydrogen 2.949 N/A LEU 64.A N THR 21.A O no hydrogen 3.023 N/A GLN 66.A N GLN 19.A O no hydrogen 2.822 N/A GLN 66.A NE2 ASN 69.A O no hydrogen 3.529 N/A ALA 67.A N VAL 70.A O no hydrogen 2.918 N/A VAL 70.A N ALA 67.A O no hydrogen 3.001 N/A LEU 72.A N VAL 65.A O no hydrogen 3.082 N/A ILE 75.A N LYS 87.A O no hydrogen 2.824 N/A GLY 76.A N LYS 87.A O no hydrogen 3.288 N/A HIS 77.A ND1 ASN 60.A OD1 no hydrogen 2.661 N/A SER 78.A N LYS 85.A O no hydrogen 2.947 N/A GLN 80.A N VAL 83.A O no hydrogen 2.869 N/A ASN 81.A ND2 GLU 173.A O no hydrogen 2.890 N/A CYS 82.A N GLY 174.A O no hydrogen 2.908 N/A CYS 82.A SG ASP 182.A OD1 no hydrogen 3.538 N/A CYS 82.A SG ASP 182.A OD2 no hydrogen 3.831 N/A VAL 83.A N GLN 80.A O no hydrogen 3.021 N/A LEU 84.A N CYS 38.A O no hydrogen 2.835 N/A LYS 85.A N SER 78.A O no hydrogen 2.698 N/A LYS 85.A NZ GLN 80.A OE1 no hydrogen 2.516 N/A LEU 86.A N VAL 36.A O no hydrogen 2.918 N/A LYS 87.A N GLY 76.A O no hydrogen 2.805 N/A VAL 88.A N ASP 34.A O no hydrogen 2.879 N/A ASP 89.A N ARG 73.A O no hydrogen 3.032 N/A THR 90.A OG1 ASP 89.A OD1 no hydrogen 2.545 N/A ASN 92.A N ASP 33.A O no hydrogen 2.813 N/A ASN 92.A ND2 GLY 15.A O no hydrogen 3.164 N/A ASN 92.A ND2 TRP 31.A O no hydrogen 2.732 N/A LYS 94.A N ASN 92.A OD1 no hydrogen 2.894 N/A THR 95.A N ASN 92.A O no hydrogen 3.027 N/A THR 95.A OG1 ASN 92.A O no hydrogen 2.856 N/A TYR 98.A OH ASP 33.A OD2 no hydrogen 2.826 N/A LYS 99.A N VAL 153.A O no hydrogen 3.011 N/A VAL 101.A N PHE 155.A O no hydrogen 2.946 N/A ARG 102.A NH1 ASP 171.A OD2 no hydrogen 3.146 N/A ARG 102.A NH1 ASN 175.A O no hydrogen 2.943 N/A ARG 102.A NH1 PHE 176.A O no hydrogen 3.317 N/A ARG 102.A NH2 PHE 176.A O no hydrogen 2.623 N/A ILE 103.A N TYR 177.A OH no hydrogen 3.066 N/A GLN 104.A N GLN 107.A OE1 no hydrogen 2.971 N/A GLY 106.A N MET 127.A O no hydrogen 2.499 N/A GLN 107.A N GLN 104.A O no hydrogen 3.021 N/A THR 108.A OG1 ASP 289.A OD1 no hydrogen 3.265 N/A THR 108.A OG1 ASP 289.A OD2 no hydrogen 2.423 N/A PHE 109.A N CYS 125.A O no hydrogen 2.984 N/A SER 110.A N PHE 147.A O no hydrogen 2.836 N/A SER 110.A OG GLN 124.A OE1 no hydrogen 2.948 N/A VAL 111.A N TYR 123.A O no hydrogen 2.846 N/A LEU 112.A N VAL 145.A O no hydrogen 3.230 N/A ALA 113.A N GLY 121.A O no hydrogen 2.797 N/A CYS 114.A N SER 144.A OG no hydrogen 2.891 N/A CYS 114.A SG LEU 112.A O no hydrogen 3.569 N/A TYR 115.A N SER 118.A O no hydrogen 2.824 N/A GLY 117.A N ASN 28.A OD1 no hydrogen 2.697 N/A SER 118.A N TYR 115.A O no hydrogen 2.597 N/A SER 120.A N ALA 113.A O no hydrogen 2.710 N/A TYR 123.A N VAL 111.A O no hydrogen 3.123 N/A CYS 125.A N PHE 109.A O no hydrogen 2.773 N/A MET 127.A N GLN 107.A O no hydrogen 2.985 N/A ARG 128.A N THR 132.A O no hydrogen 2.953 N/A ARG 128.A NE ASP 191.A OD1 no hydrogen 3.316 N/A ARG 128.A NE ASP 191.A OD2 no hydrogen 3.025 N/A ARG 128.A NH1 ASP 283.A OD1 no hydrogen 2.915 N/A ARG 128.A NH1 ASP 283.A OD2 no hydrogen 3.271 N/A ARG 128.A NH1 GLU 284.A OE2 no hydrogen 3.518 N/A ARG 128.A NH2 THR 192.A O no hydrogen 2.896 N/A ARG 128.A NH2 ASP 283.A OD2 no hydrogen 2.824 N/A ASN 130.A ND2 GLY 189.A O no hydrogen 3.366 N/A PHE 131.A N ARG 128.A O no hydrogen 2.909 N/A THR 132.A N ASN 130.A OD1 no hydrogen 3.133 N/A THR 132.A OG1 ASN 130.A OD1 no hydrogen 2.834 N/A ILE 133.A N HIS 167.A O no hydrogen 2.809 N/A GLY 135.A N HIS 167.A ND1 no hydrogen 3.056 N/A SER 136.A N TYR 123.A OH no hydrogen 3.047 N/A LEU 138.A N TYR 115.A OH no hydrogen 2.719 N/A SER 141.A N LEU 138.A O no hydrogen 3.018 N/A SER 141.A OG LEU 138.A O no hydrogen 2.977 N/A CYS 142.A SG HIS 41.A NE2 no hydrogen 3.582 N/A CYS 142.A SG HIS 160.A O no hydrogen 3.190 N/A GLY 143.A N HIS 159.A O no hydrogen 3.064 N/A SER 144.A N SER 141.A O no hydrogen 3.021 N/A SER 144.A OG SER 141.A O no hydrogen 2.687 N/A GLY 146.A N TYR 157.A O no hydrogen 2.925 N/A PHE 147.A N SER 110.A O no hydrogen 2.729 N/A ASN 148.A N SER 154.A O no hydrogen 3.009 N/A ASN 148.A ND2 THR 108.A O no hydrogen 2.940 N/A ASP 150.A N CYS 152.A O no hydrogen 2.769 N/A CYS 152.A N ASP 150.A O no hydrogen 3.182 N/A VAL 153.A N LYS 97.A O no hydrogen 2.803 N/A SER 154.A N ASN 148.A O no hydrogen 2.883 N/A SER 154.A OG ASN 148.A O no hydrogen 3.361 N/A PHE 155.A N LYS 99.A O no hydrogen 2.882 N/A CYS 156.A N GLY 146.A O no hydrogen 3.011 N/A CYS 156.A SG GLY 146.A O no hydrogen 3.680 N/A TYR 157.A N GLY 146.A O no hydrogen 3.350 N/A TYR 157.A OH HIS 159.A ND1 no hydrogen 3.261 N/A MET 158.A N THR 170.A O no hydrogen 2.730 N/A HIS 159.A N SER 144.A O no hydrogen 2.898 N/A HIS 159.A ND1 TYR 157.A OH no hydrogen 3.261 N/A HIS 160.A N ALA 168.A O no hydrogen 3.198 N/A HIS 160.A ND1 MET 158.A O no hydrogen 3.062 N/A HIS 160.A NE2 CYS 82.A O no hydrogen 3.351 N/A MET 161.A N ALA 168.A O no hydrogen 3.157 N/A LEU 163.A N VAL 166.A O no hydrogen 2.837 N/A HIS 167.A N ILE 133.A O no hydrogen 2.926 N/A ALA 168.A N MET 161.A O no hydrogen 3.105 N/A THR 170.A N MET 158.A O no hydrogen 3.119 N/A THR 170.A OG1 ASP 171.A O no hydrogen 2.721 N/A ASP 171.A N ASN 175.A O no hydrogen 2.957 N/A GLU 173.A N ASP 171.A OD1 no hydrogen 3.178 N/A GLY 174.A N ASP 171.A O no hydrogen 2.965 N/A ASN 175.A N ASP 171.A OD1 no hydrogen 3.014 N/A TYR 177.A N GLY 169.A O no hydrogen 2.846 N/A TYR 177.A OH CYS 156.A O no hydrogen 2.575 N/A VAL 181.A N GLN 186.A OE1 no hydrogen 3.044 N/A ASP 182.A N ASP 182.A OD1 no hydrogen 2.518 N/A GLN 186.A NE2 VAL 181.A O no hydrogen 2.994 N/A GLN 186.A NE2 ARG 183.A O no hydrogen 2.975 N/A THR 192.A OG1 GLU 234.A OE2 no hydrogen 2.419 N/A THR 193.A N ASN 232.A O no hydrogen 3.005 N/A ILE 194.A N ASP 283.A OD2 no hydrogen 2.787 N/A THR 195.A OG1 GLU 234.A O no hydrogen 2.466 N/A ASN 197.A ND2 GLY 106.A O no hydrogen 2.972 N/A ASN 197.A ND2 ASP 283.A O no hydrogen 2.827 N/A VAL 198.A N ILE 194.A O no hydrogen 3.075 N/A LEU 199.A N THR 195.A O no hydrogen 2.865 N/A ALA 200.A N VAL 196.A O no hydrogen 3.039 N/A TRP 201.A N ASN 197.A O no hydrogen 2.909 N/A LEU 202.A N VAL 198.A O no hydrogen 2.939 N/A TYR 203.A N LEU 199.A O no hydrogen 2.924 N/A TYR 203.A OH ILE 253.A O no hydrogen 2.965 N/A ALA 204.A N ALA 200.A O no hydrogen 2.804 N/A ALA 205.A N TRP 201.A O no hydrogen 2.899 N/A VAL 206.A N LEU 202.A O no hydrogen 2.985 N/A ILE 207.A N TYR 203.A O no hydrogen 3.028 N/A ASN 208.A N ALA 204.A O no hydrogen 3.033 N/A ASN 208.A N ALA 205.A O no hydrogen 2.945 N/A ASN 208.A ND2 ALA 204.A O no hydrogen 3.129 N/A GLY 209.A N VAL 206.A O no hydrogen 3.039 N/A ASP 210.A N ALA 205.A O no hydrogen 3.008 N/A TRP 212.A NE1 THR 274.A O no hydrogen 2.857 N/A LEU 214.A N ARG 211.A O no hydrogen 2.959 N/A ASN 215.A N SER 261.A OG no hydrogen 2.964 N/A THR 218.A OG1 THR 219.A O no hydrogen 3.559 N/A THR 218.A OG1 ASP 257.A OD1 no hydrogen 2.924 N/A THR 220.A N THR 219.A OG1 no hydrogen 2.728 N/A ASP 223.A N THR 220.A OG1 no hydrogen 2.683 N/A PHE 224.A N THR 220.A O no hydrogen 2.594 N/A ASN 225.A N LEU 221.A O no hydrogen 2.937 N/A ASN 225.A ND2 LEU 236.A O no hydrogen 2.915 N/A LEU 226.A N ASN 222.A O no hydrogen 3.026 N/A ALA 228.A N PHE 224.A O no hydrogen 2.878 N/A MET 229.A N ASN 225.A O no hydrogen 2.969 N/A LYS 230.A N LEU 226.A O no hydrogen 3.321 N/A TYR 231.A N VAL 227.A O no hydrogen 3.125 N/A TYR 231.A N ALA 228.A O no hydrogen 3.174 N/A ASN 232.A N MET 229.A O no hydrogen 3.162 N/A TYR 233.A N ALA 228.A O no hydrogen 2.855 N/A GLU 234.A N THR 193.A O no hydrogen 2.792 N/A LEU 236.A N ASN 225.A OD1 no hydrogen 2.757 N/A THR 237.A N HIS 240.A ND1 no hydrogen 3.289 N/A GLN 238.A NE2 ASP 242.A OD1 no hydrogen 3.106 N/A HIS 240.A N THR 237.A OG1 no hydrogen 3.308 N/A VAL 241.A N THR 237.A O no hydrogen 2.873 N/A ASP 242.A N GLN 238.A O no hydrogen 2.723 N/A ILE 243.A N ASP 239.A O no hydrogen 2.827 N/A LEU 244.A N VAL 241.A O no hydrogen 3.061 N/A GLY 245.A N ASP 242.A O no hydrogen 3.289 N/A SER 248.A N LEU 244.A O no hydrogen 2.883 N/A SER 248.A OG ILE 253.A O no hydrogen 3.075 N/A ALA 249.A N GLY 245.A O no hydrogen 2.833 N/A GLN 250.A N PRO 246.A O no hydrogen 2.927 N/A THR 251.A N LEU 247.A O no hydrogen 3.150 N/A THR 251.A OG1 LEU 247.A O no hydrogen 3.321 N/A GLY 252.A N ALA 249.A O no hydrogen 3.318 N/A ILE 253.A N SER 248.A O no hydrogen 3.090 N/A MET 258.A N ALA 254.A O no hydrogen 2.865 N/A CYS 259.A N VAL 255.A O no hydrogen 2.676 N/A CYS 259.A SG VAL 255.A O no hydrogen 3.340 N/A ALA 260.A N LEU 256.A O no hydrogen 3.043 N/A SER 261.A N ASP 257.A O no hydrogen 3.030 N/A SER 261.A OG PHE 213.A O no hydrogen 3.005 N/A LEU 262.A N MET 258.A O no hydrogen 2.899 N/A LYS 263.A N CYS 259.A O no hydrogen 2.840 N/A GLU 264.A N ALA 260.A O no hydrogen 3.051 N/A LEU 265.A N SER 261.A O no hydrogen 3.079 N/A LEU 266.A N LEU 262.A O no hydrogen 2.837 N/A GLN 267.A N LYS 263.A O no hydrogen 3.050 N/A ASN 268.A N GLU 264.A O no hydrogen 2.815 N/A GLY 269.A N LEU 265.A O no hydrogen 2.914 N/A ARG 273.A N MET 270.A O no hydrogen 3.165 N/A ILE 275.A N SER 278.A O no hydrogen 2.835 N/A LEU 276.A N ASP 210.A OD2 no hydrogen 3.357 N/A SER 278.A N ILE 275.A O no hydrogen 2.978 N/A SER 278.A OG LEU 280.A O no hydrogen 2.935 N/A LEU 280.A N SER 278.A OG no hydrogen 3.154 N/A THR 286.A N ASP 289.A OD2 no hydrogen 3.073 N/A ASP 289.A N THR 286.A OG1 no hydrogen 2.790 N/A VAL 290.A N THR 286.A O no hydrogen 2.859 N/A VAL 291.A N PRO 287.A O no hydrogen 2.962 N/A ARG 292.A N PHE 288.A O no hydrogen 2.798 N/A ARG 292.A NH1 ASP 289.A OD1 no hydrogen 3.449 N/A ARG 292.A NH2 ASP 289.A OD1 no hydrogen 3.052 N/A GLN 293.A N ASP 289.A O no hydrogen 3.108 N/A GLN 293.A NE2 ARG 4.A O no hydrogen 2.810 N/A CYS 294.A N VAL 290.A O no hydrogen 2.912 N/A CYS 294.A SG VAL 290.A O no hydrogen 3.233 N/A SER 295.A N VAL 291.A O no hydrogen 2.955 N/A SER 295.A OG VAL 291.A O no hydrogen 2.729 N/A GLY 296.A N ARG 292.A O no hydrogen 2.692 N/A VAL 297.A N ARG 292.A O no hydrogen 2.934 N/A