Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8dif_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 4.A N GLN 291.A OE1 no hydrogen 2.792 N/A PHE 8.A N SER 111.A OG no hydrogen 2.744 N/A SER 10.A OG GLU 14.A OE2 no hydrogen 2.437 N/A GLU 14.A N SER 10.A O no hydrogen 2.839 N/A GLY 15.A N GLY 11.A O no hydrogen 3.219 N/A CYS 16.A N VAL 13.A O no hydrogen 2.913 N/A CYS 16.A SG LYS 12.A O no hydrogen 3.468 N/A MET 17.A N GLU 14.A O no hydrogen 3.249 N/A VAL 18.A N GLY 29.A O no hydrogen 3.014 N/A GLN 19.A N GLN 67.A O no hydrogen 2.917 N/A VAL 20.A N LEU 27.A O no hydrogen 2.760 N/A THR 21.A N LEU 65.A O no hydrogen 2.728 N/A THR 21.A OG1 THR 26.A OG1 no hydrogen 2.598 N/A CYS 22.A N THR 25.A O no hydrogen 2.895 N/A CYS 22.A SG ASN 63.A O no hydrogen 3.876 N/A THR 25.A OG1 CYS 44.A O no hydrogen 3.402 N/A THR 26.A OG1 THR 21.A OG1 no hydrogen 2.598 N/A LEU 27.A N VAL 20.A O no hydrogen 2.845 N/A ASN 28.A N CYS 143.A O no hydrogen 3.188 N/A ASN 28.A ND2 CYS 115.A O no hydrogen 3.015 N/A ASN 28.A ND2 GLY 141.A O no hydrogen 2.934 N/A ASN 28.A ND2 CYS 143.A O no hydrogen 3.048 N/A GLY 29.A N VAL 18.A O no hydrogen 2.830 N/A LEU 30.A N TYR 37.A O no hydrogen 2.732 N/A TRP 31.A N CYS 16.A O no hydrogen 2.832 N/A LEU 32.A N VAL 35.A O no hydrogen 3.053 N/A ASP 33.A N THR 96.A OG1 no hydrogen 3.019 N/A VAL 35.A N LEU 32.A O no hydrogen 3.150 N/A VAL 36.A N LEU 87.A O no hydrogen 2.817 N/A TYR 37.A N LEU 30.A O no hydrogen 2.735 N/A CYS 38.A N LEU 85.A O no hydrogen 3.095 N/A CYS 38.A SG PRO 39.A O no hydrogen 3.579 N/A ARG 40.A N CYS 83.A O no hydrogen 2.967 N/A ARG 40.A NE ASP 181.A OD2 no hydrogen 2.594 N/A ARG 40.A NH2 ASP 181.A OD1 no hydrogen 2.926 N/A VAL 42.A N PRO 39.A O no hydrogen 3.120 N/A ILE 43.A N ARG 40.A O no hydrogen 3.228 N/A CYS 44.A N HIS 41.A O no hydrogen 2.960 N/A CYS 44.A SG TYR 52.A OH no hydrogen 3.853 N/A THR 45.A N ASP 46.A OD2 no hydrogen 2.960 N/A TYR 52.A OH ASP 181.A O no hydrogen 2.816 N/A ASP 54.A N ASN 51.A OD1 no hydrogen 3.309 N/A LEU 55.A N ASN 51.A O no hydrogen 2.920 N/A LEU 56.A N TYR 52.A O no hydrogen 2.825 N/A ILE 57.A N GLU 53.A O no hydrogen 2.990 N/A LYS 59.A N LEU 56.A O no hydrogen 2.917 N/A SER 60.A N ASN 63.A OD1 no hydrogen 2.940 N/A ASN 63.A N SER 60.A O no hydrogen 2.927 N/A PHE 64.A N ASN 61.A O no hydrogen 3.078 N/A LEU 65.A N THR 21.A O no hydrogen 2.812 N/A GLN 67.A N GLN 19.A O no hydrogen 2.906 N/A ALA 68.A N VAL 71.A O no hydrogen 2.794 N/A VAL 71.A N ALA 68.A O no hydrogen 3.355 N/A LEU 73.A N VAL 66.A O no hydrogen 2.899 N/A ILE 76.A N LYS 88.A O no hydrogen 2.813 N/A HIS 78.A ND1 ASN 61.A OD1 no hydrogen 2.595 N/A SER 79.A N LYS 86.A O no hydrogen 3.028 N/A GLN 81.A N VAL 84.A O no hydrogen 2.896 N/A ASN 82.A ND2 GLU 173.A O no hydrogen 2.904 N/A CYS 83.A N GLY 174.A O no hydrogen 3.022 N/A CYS 83.A SG ASP 181.A OD1 no hydrogen 3.744 N/A CYS 83.A SG ASP 181.A OD2 no hydrogen 3.578 N/A VAL 84.A N GLN 81.A O no hydrogen 2.962 N/A LEU 85.A N CYS 38.A O no hydrogen 2.733 N/A LYS 86.A N SER 79.A O no hydrogen 2.804 N/A LYS 86.A NZ GLN 81.A OE1 no hydrogen 2.589 N/A LEU 87.A N VAL 36.A O no hydrogen 2.823 N/A LYS 88.A N GLY 77.A O no hydrogen 2.882 N/A VAL 89.A N ASP 34.A O no hydrogen 2.895 N/A ASP 90.A N ARG 74.A O no hydrogen 3.013 N/A THR 91.A OG1 ASP 90.A OD1 no hydrogen 3.062 N/A ASN 93.A N ASP 33.A O no hydrogen 2.794 N/A ASN 93.A ND2 GLY 15.A O no hydrogen 3.188 N/A ASN 93.A ND2 TRP 31.A O no hydrogen 2.735 N/A LYS 95.A N ASN 93.A OD1 no hydrogen 2.926 N/A THR 96.A N ASN 93.A O no hydrogen 3.117 N/A THR 96.A OG1 ASN 93.A O no hydrogen 2.650 N/A TYR 99.A OH ASP 33.A OD2 no hydrogen 2.966 N/A LYS 100.A N VAL 153.A O no hydrogen 2.891 N/A VAL 102.A N PHE 155.A O no hydrogen 2.882 N/A ARG 103.A NH1 ASP 171.A OD2 no hydrogen 2.999 N/A ARG 103.A NH1 ASN 175.A O no hydrogen 3.014 N/A ARG 103.A NH1 PHE 176.A O no hydrogen 3.345 N/A ARG 103.A NH2 PHE 176.A O no hydrogen 2.961 N/A GLN 105.A N GLN 108.A OE1 no hydrogen 2.930 N/A GLY 107.A N MET 128.A O no hydrogen 2.762 N/A GLN 108.A N GLN 105.A O no hydrogen 3.053 N/A THR 109.A OG1 ASP 287.A OD1 no hydrogen 3.256 N/A THR 109.A OG1 ASP 287.A OD2 no hydrogen 2.491 N/A PHE 110.A N CYS 126.A O no hydrogen 2.775 N/A SER 111.A N PHE 148.A O no hydrogen 3.053 N/A SER 111.A OG GLN 125.A OE1 no hydrogen 2.796 N/A VAL 112.A N TYR 124.A O no hydrogen 2.883 N/A LEU 113.A N VAL 146.A O no hydrogen 3.241 N/A ALA 114.A N GLY 122.A O no hydrogen 2.888 N/A CYS 115.A N SER 145.A OG no hydrogen 3.182 N/A CYS 115.A SG LEU 113.A O no hydrogen 3.658 N/A TYR 116.A N SER 119.A O no hydrogen 3.065 N/A GLY 118.A N ASN 28.A OD1 no hydrogen 2.717 N/A SER 119.A N TYR 116.A O no hydrogen 2.789 N/A SER 121.A N ALA 114.A O no hydrogen 2.769 N/A TYR 124.A N VAL 112.A O no hydrogen 3.187 N/A TYR 124.A OH SER 137.A O no hydrogen 3.356 N/A CYS 126.A N PHE 110.A O no hydrogen 2.702 N/A MET 128.A N GLN 108.A O no hydrogen 2.969 N/A ARG 129.A N THR 133.A O no hydrogen 2.874 N/A ARG 129.A NE ASP 191.A OD2 no hydrogen 2.837 N/A ARG 129.A NH1 ASP 281.A OD1 no hydrogen 2.929 N/A ARG 129.A NH1 ASP 281.A OD2 no hydrogen 3.297 N/A ARG 129.A NH1 GLU 282.A OE2 no hydrogen 3.058 N/A ARG 129.A NH2 THR 192.A O no hydrogen 2.975 N/A ARG 129.A NH2 ASP 281.A OD2 no hydrogen 2.621 N/A ASN 131.A ND2 GLY 189.A O no hydrogen 3.130 N/A PHE 132.A N ARG 129.A O no hydrogen 2.744 N/A THR 133.A N ASN 131.A OD1 no hydrogen 3.264 N/A THR 133.A OG1 ASN 131.A OD1 no hydrogen 2.877 N/A ILE 134.A N HIS 167.A O no hydrogen 2.870 N/A GLY 136.A N HIS 167.A ND1 no hydrogen 2.970 N/A SER 137.A N TYR 124.A OH no hydrogen 3.098 N/A LEU 139.A N TYR 116.A OH no hydrogen 2.944 N/A SER 142.A N LEU 139.A O no hydrogen 2.953 N/A SER 142.A OG LEU 139.A O no hydrogen 2.892 N/A CYS 143.A SG HIS 41.A NE2 no hydrogen 3.510 N/A CYS 143.A SG HIS 160.A O no hydrogen 3.158 N/A GLY 144.A N HIS 159.A O no hydrogen 2.952 N/A SER 145.A N SER 142.A O no hydrogen 3.026 N/A SER 145.A OG CYS 115.A O no hydrogen 3.460 N/A SER 145.A OG SER 142.A O no hydrogen 2.545 N/A GLY 147.A N TYR 157.A O no hydrogen 2.795 N/A PHE 148.A N SER 111.A O no hydrogen 2.826 N/A ASN 149.A N SER 154.A O no hydrogen 2.852 N/A ASN 149.A ND2 THR 109.A O no hydrogen 2.948 N/A ASP 151.A N CYS 152.A O no hydrogen 2.971 N/A VAL 153.A N LYS 98.A O no hydrogen 2.790 N/A SER 154.A N ASN 149.A O no hydrogen 2.655 N/A PHE 155.A N LYS 100.A O no hydrogen 2.922 N/A CYS 156.A N GLY 147.A O no hydrogen 2.998 N/A TYR 157.A N GLY 147.A O no hydrogen 3.327 N/A TYR 157.A OH HIS 159.A ND1 no hydrogen 3.233 N/A MET 158.A N THR 170.A O no hydrogen 2.714 N/A HIS 159.A N SER 145.A O no hydrogen 2.917 N/A HIS 159.A ND1 TYR 157.A OH no hydrogen 3.233 N/A HIS 160.A N ALA 168.A O no hydrogen 3.213 N/A MET 161.A N ALA 168.A O no hydrogen 3.082 N/A LEU 163.A N VAL 166.A O no hydrogen 2.880 N/A HIS 167.A N ILE 134.A O no hydrogen 2.875 N/A ALA 168.A N MET 161.A O no hydrogen 3.091 N/A THR 170.A N MET 158.A O no hydrogen 2.944 N/A THR 170.A OG1 HIS 160.A NE2 no hydrogen 2.938 N/A THR 170.A OG1 ASP 171.A O no hydrogen 2.802 N/A ASP 171.A N ASN 175.A O no hydrogen 3.123 N/A GLU 173.A N ASP 171.A OD1 no hydrogen 3.127 N/A GLY 174.A N ASP 171.A O no hydrogen 2.900 N/A ASN 175.A N ASP 171.A OD1 no hydrogen 2.879 N/A ASN 175.A ND2 ASP 171.A OD1 no hydrogen 3.467 N/A ASN 175.A ND2 ASP 171.A OD2 no hydrogen 3.503 N/A VAL 180.A N GLN 186.A OE1 no hydrogen 2.993 N/A ASP 181.A N ASP 181.A OD1 no hydrogen 2.615 N/A GLN 183.A N MET 47.A O no hydrogen 2.669 N/A GLN 186.A NE2 VAL 180.A O no hydrogen 3.064 N/A GLN 186.A NE2 ARG 182.A O no hydrogen 3.021 N/A GLN 186.A NE2 THR 184.A O no hydrogen 3.595 N/A THR 192.A N ASP 191.A OD1 no hydrogen 2.880 N/A THR 192.A OG1 GLU 232.A OE2 no hydrogen 2.343 N/A THR 193.A N ASN 230.A O no hydrogen 2.938 N/A ILE 194.A N ASP 281.A OD2 no hydrogen 2.834 N/A THR 195.A OG1 GLU 232.A O no hydrogen 2.351 N/A ASN 197.A ND2 GLY 107.A O no hydrogen 3.152 N/A ASN 197.A ND2 ASP 281.A O no hydrogen 2.789 N/A VAL 198.A N ILE 194.A O no hydrogen 3.043 N/A LEU 199.A N THR 195.A O no hydrogen 2.941 N/A ALA 200.A N VAL 196.A O no hydrogen 2.999 N/A TRP 201.A N ASN 197.A O no hydrogen 2.936 N/A LEU 202.A N VAL 198.A O no hydrogen 2.909 N/A TYR 203.A N LEU 199.A O no hydrogen 2.919 N/A TYR 203.A OH ILE 251.A O no hydrogen 2.988 N/A ALA 204.A N ALA 200.A O no hydrogen 2.827 N/A ALA 205.A N TRP 201.A O no hydrogen 2.814 N/A VAL 206.A N LEU 202.A O no hydrogen 3.007 N/A ILE 207.A N TYR 203.A O no hydrogen 2.888 N/A ASN 208.A N ALA 204.A O no hydrogen 3.087 N/A ASN 208.A N ALA 205.A O no hydrogen 3.148 N/A ASN 208.A ND2 ALA 204.A O no hydrogen 3.082 N/A GLY 209.A N VAL 206.A O no hydrogen 3.050 N/A ASP 210.A N ALA 205.A O no hydrogen 2.857 N/A TRP 212.A NE1 THR 272.A O no hydrogen 2.913 N/A LEU 214.A N ARG 211.A O no hydrogen 2.859 N/A ASN 215.A N SER 259.A OG no hydrogen 3.037 N/A THR 216.A OG1 ASP 255.A OD1 no hydrogen 2.867 N/A THR 217.A N THR 216.A OG1 no hydrogen 2.716 N/A THR 217.A OG1 THR 218.A O no hydrogen 3.309 N/A THR 217.A OG1 ASP 221.A OD2 no hydrogen 2.544 N/A ASP 221.A N THR 218.A OG1 no hydrogen 2.717 N/A PHE 222.A N THR 218.A O no hydrogen 2.722 N/A ASN 223.A N LEU 219.A O no hydrogen 2.968 N/A ASN 223.A ND2 LEU 234.A O no hydrogen 3.044 N/A LEU 224.A N ASN 220.A O no hydrogen 3.248 N/A VAL 225.A N ASP 221.A O no hydrogen 3.363 N/A ALA 226.A N PHE 222.A O no hydrogen 2.769 N/A MET 227.A N ASN 223.A O no hydrogen 2.919 N/A TYR 229.A N VAL 225.A O no hydrogen 3.254 N/A TYR 229.A N ALA 226.A O no hydrogen 3.111 N/A ASN 230.A N MET 227.A O no hydrogen 3.214 N/A TYR 231.A N ALA 226.A O no hydrogen 2.776 N/A GLU 232.A N THR 193.A O no hydrogen 2.793 N/A LEU 234.A N ASN 223.A OD1 no hydrogen 2.931 N/A THR 235.A N HIS 238.A ND1 no hydrogen 3.272 N/A GLN 236.A NE2 ASP 240.A OD1 no hydrogen 3.226 N/A HIS 238.A N THR 235.A OG1 no hydrogen 3.214 N/A VAL 239.A N THR 235.A O no hydrogen 3.021 N/A ASP 240.A N GLN 236.A O no hydrogen 2.852 N/A ILE 241.A N ASP 237.A O no hydrogen 2.933 N/A LEU 242.A N HIS 238.A O no hydrogen 3.197 N/A LEU 242.A N VAL 239.A O no hydrogen 3.202 N/A GLY 243.A N ASP 240.A O no hydrogen 3.080 N/A SER 246.A N LEU 242.A O no hydrogen 3.035 N/A SER 246.A OG ILE 251.A O no hydrogen 2.715 N/A ALA 247.A N GLY 243.A O no hydrogen 2.922 N/A GLN 248.A N PRO 244.A O no hydrogen 3.073 N/A THR 249.A N LEU 245.A O no hydrogen 2.898 N/A THR 249.A OG1 LEU 245.A O no hydrogen 3.179 N/A THR 249.A OG1 SER 246.A O no hydrogen 3.520 N/A ILE 251.A N THR 249.A OG1 no hydrogen 3.176 N/A MET 256.A N ALA 252.A O no hydrogen 2.904 N/A CYS 257.A N VAL 253.A O no hydrogen 2.868 N/A CYS 257.A SG VAL 253.A O no hydrogen 3.094 N/A ALA 258.A N LEU 254.A O no hydrogen 3.205 N/A ALA 258.A N ASP 255.A O no hydrogen 3.051 N/A SER 259.A N ASP 255.A O no hydrogen 3.189 N/A SER 259.A OG PHE 213.A O no hydrogen 3.221 N/A LEU 260.A N MET 256.A O no hydrogen 2.999 N/A LYS 261.A N CYS 257.A O no hydrogen 2.964 N/A LYS 261.A NZ ASP 221.A OD2 no hydrogen 3.153 N/A GLU 262.A N ALA 258.A O no hydrogen 2.954 N/A LEU 263.A N SER 259.A O no hydrogen 2.906 N/A LEU 264.A N LEU 260.A O no hydrogen 2.670 N/A GLN 265.A N LYS 261.A O no hydrogen 2.799 N/A ASN 266.A N GLU 262.A O no hydrogen 2.696 N/A ASN 266.A ND2 GLU 262.A OE1 no hydrogen 3.560 N/A ARG 271.A N MET 268.A O no hydrogen 3.129 N/A ILE 273.A N SER 276.A O no hydrogen 2.788 N/A LEU 274.A N ASP 210.A OD2 no hydrogen 2.945 N/A SER 276.A N ILE 273.A O no hydrogen 2.981 N/A SER 276.A OG LEU 278.A O no hydrogen 3.158 N/A LEU 278.A N SER 276.A OG no hydrogen 3.349 N/A THR 284.A N ASP 287.A OD2 no hydrogen 3.072 N/A ASP 287.A N THR 284.A OG1 no hydrogen 2.789 N/A VAL 288.A N THR 284.A O no hydrogen 3.044 N/A VAL 289.A N PRO 285.A O no hydrogen 3.048 N/A ARG 290.A N PHE 286.A O no hydrogen 2.811 N/A ARG 290.A NH1 ASP 287.A OD1 no hydrogen 3.163 N/A ARG 290.A NH2 ASP 287.A OD1 no hydrogen 3.142 N/A GLN 291.A N ASP 287.A O no hydrogen 2.990 N/A GLN 291.A NE2 ARG 4.A O no hydrogen 2.766 N/A CYS 292.A N VAL 288.A O no hydrogen 2.868 N/A CYS 292.A SG VAL 288.A O no hydrogen 3.279 N/A