Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8dpk_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 4.A ND2 SER 48.A O no hydrogen 2.644 N/A ASN 4.A ND2 LEU 49.A O no hydrogen 2.656 N/A LEU 6.A N ASN 4.A OD1 no hydrogen 3.336 N/A HIS 7.A N LEU 273.A O no hydrogen 3.104 N/A HIS 7.A ND1 HIS 54.A NE2 no hydrogen 2.880 N/A ALA 8.A N LYS 52.A O no hydrogen 2.932 N/A PHE 9.A N LEU 271.A O no hydrogen 3.090 N/A VAL 10.A N HIS 54.A O no hydrogen 2.931 N/A ARG 11.A NE SER 57.A O no hydrogen 3.031 N/A ARG 11.A NH1 ALA 64.A O no hydrogen 2.784 N/A ARG 11.A NH2 SER 96.A OG no hydrogen 2.835 N/A SER 12.A OG GLU 58.A OE1 no hydrogen 3.444 N/A HIS 14.A ND1 THR 17.A OG1 no hydrogen 2.798 N/A TYR 15.A OH ASP 31.A OD1 no hydrogen 2.559 N/A THR 17.A N HIS 14.A O no hydrogen 3.067 N/A THR 17.A OG1 HIS 14.A ND1 no hydrogen 2.798 N/A THR 17.A OG1 HIS 14.A O no hydrogen 3.379 N/A ILE 18.A N TYR 15.A O no hydrogen 3.499 N/A GLY 22.A N ILE 26.A O no hydrogen 2.940 N/A GLY 25.A N GLY 22.A O no hydrogen 2.886 N/A VAL 28.A N SER 20.A O no hydrogen 2.918 N/A ASN 29.A N GLU 258.A OE2 no hydrogen 2.699 N/A MET 32.A N ASN 29.A OD1 no hydrogen 2.928 N/A LEU 33.A N ASN 29.A O no hydrogen 2.758 N/A VAL 34.A N ARG 30.A O no hydrogen 3.065 N/A HIS 35.A N ASP 31.A O no hydrogen 3.215 N/A GLN 36.A N MET 32.A O no hydrogen 2.807 N/A GLN 36.A NE2 SER 257.A OG no hydrogen 2.729 N/A PHE 37.A N LEU 33.A O no hydrogen 2.961 N/A ARG 38.A N VAL 34.A O no hydrogen 3.154 N/A ASP 39.A N HIS 35.A O no hydrogen 3.086 N/A PHE 40.A N GLN 36.A O no hydrogen 2.714 N/A TYR 41.A N PHE 37.A O no hydrogen 2.768 N/A LYS 42.A N ARG 38.A O no hydrogen 3.060 N/A LYS 42.A NZ ASP 39.A OD1 no hydrogen 3.532 N/A THR 43.A N ASP 39.A O no hydrogen 2.854 N/A THR 43.A OG1 ASP 39.A O no hydrogen 2.878 N/A LEU 44.A N PHE 40.A O no hydrogen 2.933 N/A GLN 45.A N TYR 41.A O no hydrogen 3.249 N/A GLN 45.A N LYS 42.A O no hydrogen 3.214 N/A HIS 46.A N THR 43.A O no hydrogen 3.302 N/A CYS 47.A SG THR 43.A O no hydrogen 3.260 N/A CYS 47.A SG LEU 44.A O no hydrogen 3.298 N/A SER 48.A N ASP 230.A OD2 no hydrogen 2.918 N/A ASP 51.A N LEU 6.A O no hydrogen 2.788 N/A HIS 54.A N ALA 8.A O no hydrogen 2.719 N/A HIS 54.A NE2 HIS 7.A ND1 no hydrogen 2.880 N/A MET 56.A N VAL 10.A O no hydrogen 2.721 N/A SER 57.A N TYR 99.A OH no hydrogen 3.047 N/A ARG 59.A NH1 GLU 95.A OE2 no hydrogen 2.765 N/A SER 61.A N ARG 59.A O no hydrogen 2.840 N/A GLU 63.A N SER 61.A OG no hydrogen 3.337 N/A ALA 64.A N SER 61.A O no hydrogen 3.013 N/A LEU 65.A N VAL 62.A O no hydrogen 3.160 N/A ARG 66.A N GLU 63.A O no hydrogen 3.015 N/A ARG 66.A NE ASP 69.A OD2 no hydrogen 2.685 N/A ARG 66.A NH2 ASP 69.A OD1 no hydrogen 2.966 N/A ARG 66.A NH2 ASP 69.A OD2 no hydrogen 3.453 N/A ALA 68.A N ALA 268.A O no hydrogen 3.124 N/A ASP 69.A N ARG 66.A O no hydrogen 3.033 N/A GLN 70.A NE2 PHE 93.A O no hydrogen 2.872 N/A VAL 72.A N LEU 79.A O no hydrogen 3.089 N/A SER 73.A OG GLY 75.A O no hydrogen 3.510 N/A ILE 74.A N THR 77.A O no hydrogen 2.950 N/A THR 77.A N ILE 74.A O no hydrogen 2.965 N/A LEU 79.A N VAL 72.A O no hydrogen 2.818 N/A GLU 80.A N ALA 110.A O no hydrogen 3.014 N/A MET 81.A N GLN 70.A O no hydrogen 3.158 N/A MET 86.A N LEU 83.A O no hydrogen 3.129 N/A GLU 87.A N GLU 87.A OE1 no hydrogen 2.697 N/A HIS 88.A NE2 GLU 63.A OE2 no hydrogen 2.965 N/A ARG 89.A N MET 86.A O no hydrogen 3.177 N/A ARG 89.A NE GLU 92.A OE1 no hydrogen 2.937 N/A ARG 89.A NH1 ASP 69.A OD2 no hydrogen 2.870 N/A ARG 89.A NH2 ARG 66.A O no hydrogen 3.067 N/A ARG 89.A NH2 GLU 92.A OE1 no hydrogen 3.554 N/A ARG 89.A NH2 GLU 92.A OE2 no hydrogen 2.781 N/A ALA 90.A N GLU 87.A O no hydrogen 3.096 N/A PHE 93.A N ARG 89.A O no hydrogen 2.999 N/A MET 94.A N ALA 90.A O no hydrogen 2.952 N/A GLU 95.A N THR 91.A O no hydrogen 3.185 N/A SER 96.A N GLU 92.A O no hydrogen 2.924 N/A SER 96.A OG GLU 92.A O no hydrogen 3.344 N/A MET 97.A N PHE 93.A O no hydrogen 2.973 N/A MET 97.A N MET 94.A O no hydrogen 2.836 N/A ARG 98.A N MET 94.A O no hydrogen 3.223 N/A ARG 98.A N GLU 95.A O no hydrogen 3.057 N/A TYR 99.A N GLU 95.A O no hydrogen 3.390 N/A VAL 100.A N SER 96.A O no hydrogen 3.116 N/A ARG 101.A N MET 97.A O no hydrogen 2.932 N/A ARG 101.A NH1 SER 107.A O no hydrogen 2.412 N/A GLY 102.A N ARG 98.A O no hydrogen 2.801 N/A ALA 103.A N TYR 99.A O no hydrogen 3.145 N/A ALA 103.A N VAL 100.A O no hydrogen 3.290 N/A GLY 104.A N ARG 101.A O no hydrogen 3.003 N/A GLY 105.A N VAL 100.A O no hydrogen 2.895 N/A ALA 110.A N PHE 78.A O no hydrogen 2.933 N/A SER 111.A OG ASP 115.A OD2 no hydrogen 3.113 N/A GLN 114.A NE2 MET 81.A O no hydrogen 2.739 N/A ASP 115.A N SER 111.A O no hydrogen 2.851 N/A ASP 115.A N TYR 112.A O no hydrogen 3.074 N/A THR 116.A N LEU 113.A O no hydrogen 3.487 N/A THR 116.A OG1 TYR 112.A O no hydrogen 2.862 N/A CYS 119.A N THR 116.A O no hydrogen 3.385 N/A CYS 119.A SG LEU 113.A O no hydrogen 3.859 N/A ARG 120.A N ASN 142.A OD1 no hydrogen 2.889 N/A CYS 121.A SG ASN 122.A O no hydrogen 4.010 N/A ASN 122.A N THR 141.A OG1 no hydrogen 3.050 N/A SER 123.A OG ALA 68.A O no hydrogen 2.629 N/A GLY 124.A N ASN 122.A OD1 no hydrogen 2.878 N/A ASP 125.A N ASN 122.A O no hydrogen 2.856 N/A VAL 126.A N SER 123.A O no hydrogen 3.180 N/A VAL 127.A N ALA 134.A O no hydrogen 2.911 N/A CYS 128.A SG SER 73.A O no hydrogen 3.701 N/A LEU 129.A N GLY 132.A O no hydrogen 2.780 N/A ILE 133.A N ASP 160.A O no hydrogen 2.889 N/A ALA 134.A N VAL 127.A O no hydrogen 2.847 N/A VAL 135.A N PHE 162.A O no hydrogen 2.724 N/A GLY 136.A N ASP 125.A O no hydrogen 2.892 N/A HIS 137.A N LEU 164.A O no hydrogen 2.809 N/A HIS 137.A ND1 GLU 165.A OE1 no hydrogen 3.006 N/A HIS 137.A ND1 GLU 165.A OE2 no hydrogen 2.492 N/A GLY 138.A N THR 141.A O no hydrogen 3.225 N/A ARG 140.A NE ASP 125.A OD2 no hydrogen 3.090 N/A ARG 140.A NH1 ALA 170.A O no hydrogen 2.774 N/A ARG 140.A NH2 ASP 125.A OD1 no hydrogen 3.283 N/A ARG 140.A NH2 ASP 125.A OD2 no hydrogen 3.570 N/A ARG 140.A NH2 ALA 170.A O no hydrogen 3.062 N/A THR 141.A OG1 ASP 125.A OD2 no hydrogen 2.731 N/A ASN 142.A N ARG 120.A O no hydrogen 2.931 N/A ASN 142.A ND2 ASN 118.A O no hydrogen 2.566 N/A ALA 145.A N ASN 142.A OD1 no hydrogen 3.237 N/A HIS 146.A N ASN 142.A O no hydrogen 3.336 N/A HIS 146.A ND1 THR 163.A OG1 no hydrogen 2.834 N/A HIS 146.A NE2 GLY 136.A O no hydrogen 2.773 N/A THR 147.A N ALA 143.A O no hydrogen 2.820 N/A THR 147.A OG1 ALA 143.A O no hydrogen 2.999 N/A THR 148.A N VAL 144.A O no hydrogen 2.693 N/A THR 148.A OG1 VAL 144.A O no hydrogen 2.863 N/A LEU 149.A N ALA 145.A O no hydrogen 2.807 N/A LYS 150.A N HIS 146.A O no hydrogen 3.024 N/A LYS 150.A NZ THR 163.A OG1 no hydrogen 2.825 N/A GLN 151.A N THR 147.A O no hydrogen 3.170 N/A LEU 152.A N THR 148.A O no hydrogen 2.911 N/A PHE 153.A N LEU 149.A O no hydrogen 2.888 N/A PHE 153.A N LYS 150.A O no hydrogen 3.289 N/A GLU 154.A N LYS 150.A O no hydrogen 2.692 N/A VAL 155.A N PHE 159.A O no hydrogen 2.963 N/A SER 158.A OG VAL 155.A O no hydrogen 3.399 N/A SER 158.A OG ASP 160.A OD2 no hydrogen 3.203 N/A PHE 159.A N VAL 155.A O no hydrogen 3.204 N/A ASP 160.A N ASN 131.A O no hydrogen 3.089 N/A PHE 162.A N ILE 133.A O no hydrogen 2.864 N/A THR 163.A OG1 HIS 146.A ND1 no hydrogen 2.834 N/A LEU 164.A N VAL 135.A O no hydrogen 2.853 N/A GLU 165.A N GLN 199.A OE1 no hydrogen 3.149 N/A GLN 166.A N HIS 137.A O no hydrogen 2.745 N/A GLN 166.A NE2 ASP 125.A OD1 no hydrogen 3.210 N/A GLN 166.A NE2 TYR 176.A OH no hydrogen 3.059 N/A ALA 170.A N GLU 167.A O no hydrogen 3.110 N/A LEU 173.A N ASP 125.A OD1 no hydrogen 2.842 N/A GLY 174.A N GLY 124.A O no hydrogen 2.670 N/A ASP 175.A N PRO 172.A O no hydrogen 2.999 N/A TYR 176.A N LEU 173.A O no hydrogen 3.267 N/A GLY 178.A N LEU 186.A O no hydrogen 2.728 N/A ALA 180.A N VAL 184.A O no hydrogen 3.013 N/A SER 182.A OG ASN 183.A OD1 no hydrogen 3.295 N/A ASN 183.A ND2 GLU 208.A O no hydrogen 3.667 N/A VAL 184.A N ALA 180.A O no hydrogen 3.139 N/A LEU 185.A N ASN 210.A O no hydrogen 2.763 N/A LEU 186.A N GLY 178.A O no hydrogen 2.930 N/A THR 187.A N VAL 212.A O no hydrogen 3.114 N/A THR 187.A OG1 TYR 176.A O no hydrogen 3.440 N/A TRP 188.A N TYR 176.A O no hydrogen 2.965 N/A TRP 188.A NE1 CYS 218.A O no hydrogen 2.918 N/A LYS 189.A N LEU 214.A O no hydrogen 3.064 N/A GLY 193.A N ASP 190.A OD1 no hydrogen 2.919 N/A LEU 194.A N ASP 190.A O no hydrogen 3.025 N/A LEU 195.A N GLU 191.A O no hydrogen 3.027 N/A ALA 196.A N HIS 192.A O no hydrogen 3.013 N/A VAL 197.A N GLY 193.A O no hydrogen 2.882 N/A ASP 198.A N LEU 194.A O no hydrogen 2.960 N/A GLN 199.A N LEU 195.A O no hydrogen 2.952 N/A GLN 199.A NE2 GLU 165.A O no hydrogen 2.927 N/A TYR 200.A N ALA 196.A O no hydrogen 2.867 N/A GLN 201.A N VAL 197.A O no hydrogen 3.046 N/A GLN 202.A N GLN 199.A O no hydrogen 3.271 N/A LYS 203.A N GLN 199.A O no hydrogen 3.176 N/A GLN 204.A N TYR 200.A O no hydrogen 2.950 N/A GLN 204.A NE2 THR 207.A O no hydrogen 2.743 N/A HIS 206.A N GLN 204.A OE1 no hydrogen 2.709 N/A THR 207.A N GLN 204.A OE1 no hydrogen 2.578 N/A ASN 210.A N ASN 183.A O no hydrogen 3.057 N/A VAL 212.A N LEU 185.A O no hydrogen 2.641 N/A LEU 214.A N THR 187.A O no hydrogen 2.769 N/A GLU 215.A N SER 240.A OG no hydrogen 2.932 N/A CYS 218.A N GLU 215.A O no hydrogen 2.919 N/A CYS 218.A SG HIS 219.A O no hydrogen 4.008 N/A HIS 219.A NE2 ASP 260.A OD1 no hydrogen 2.740 N/A LEU 221.A N LEU 232.A O no hydrogen 2.926 N/A SER 222.A OG PHE 179.A O no hydrogen 2.707 N/A TYR 224.A OH PRO 130.A O no hydrogen 3.302 N/A THR 228.A OG1 SER 48.A OG no hydrogen 3.202 N/A VAL 231.A N ASN 250.A O no hydrogen 3.034 N/A LEU 232.A N LEU 221.A O no hydrogen 3.041 N/A VAL 233.A N ILE 252.A O no hydrogen 2.851 N/A GLN 234.A N HIS 219.A O no hydrogen 2.884 N/A GLN 234.A NE2 ASP 260.A OD2 no hydrogen 3.064 N/A LYS 235.A N VAL 254.A O no hydrogen 2.529 N/A TYR 237.A N GLN 234.A O no hydrogen 3.423 N/A SER 240.A N GLU 215.A OE2 no hydrogen 2.750 N/A SER 240.A OG GLU 215.A OE2 no hydrogen 2.446 N/A MET 241.A N TYR 237.A O no hydrogen 3.032 N/A ASP 242.A N GLU 238.A O no hydrogen 2.975 N/A SER 243.A N ARG 239.A O no hydrogen 2.813 N/A SER 243.A OG ARG 239.A O no hydrogen 3.347 N/A ILE 244.A N SER 240.A O no hydrogen 2.919 N/A ALA 245.A N MET 241.A O no hydrogen 3.095 N/A ALA 246.A N ASP 242.A O no hydrogen 2.857 N/A ALA 247.A N ILE 244.A O no hydrogen 3.124 N/A GLY 248.A N ALA 245.A O no hydrogen 3.369 N/A LEU 249.A N ILE 244.A O no hydrogen 3.383 N/A ASN 250.A N ILE 229.A O no hydrogen 2.743 N/A ASN 250.A ND2 ASP 230.A OD1 no hydrogen 2.824 N/A ILE 252.A N VAL 231.A O no hydrogen 2.772 N/A VAL 254.A N VAL 233.A O no hydrogen 2.825 N/A TRP 256.A NE1 ILE 264.A O no hydrogen 2.849 N/A SER 257.A OG GLN 255.A OE1 no hydrogen 3.367 N/A SER 257.A OG GLU 258.A OE1 no hydrogen 2.926 N/A GLU 258.A N GLN 36.A OE1 no hydrogen 3.030 N/A ASP 260.A N TRP 256.A O no hydrogen 2.829 N/A LYS 261.A N SER 257.A O no hydrogen 2.987 N/A LYS 261.A NZ GLU 258.A OE1 no hydrogen 2.714 N/A LEU 262.A N GLU 258.A O no hydrogen 3.057 N/A GLY 263.A N ASP 260.A O no hydrogen 2.973 N/A ILE 264.A N MET 259.A O no hydrogen 2.933 N/A SER 265.A OG ASP 175.A OD1 no hydrogen 2.864 N/A ARG 267.A NE ASP 175.A OD1 no hydrogen 2.764 N/A ARG 267.A NH2 ASP 175.A OD1 no hydrogen 3.232 N/A ALA 268.A N SER 265.A OG no hydrogen 2.988 N/A ALA 269.A N MET 266.A O no hydrogen 3.098 N/A VAL 270.A N ARG 267.A O no hydrogen 3.373 N/A LEU 271.A N PHE 9.A O no hydrogen 2.977 N/A LEU 273.A N HIS 7.A O no hydrogen 2.711 N/A LYS 274.A NZ SER 73.A O no hydrogen 3.146 N/A