Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8dry_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 4.A N GLN 299.A OE1 no hydrogen 2.756 N/A PHE 8.A N SER 113.A OG no hydrogen 2.871 N/A SER 10.A OG GLU 14.A OE2 no hydrogen 2.334 N/A GLU 14.A N SER 10.A O no hydrogen 2.957 N/A CYS 16.A N VAL 13.A O no hydrogen 2.752 N/A CYS 16.A SG LYS 12.A O no hydrogen 3.521 N/A MET 17.A N GLU 14.A O no hydrogen 3.298 N/A VAL 18.A N GLY 29.A O no hydrogen 2.917 N/A GLN 19.A N GLN 69.A O no hydrogen 2.985 N/A VAL 20.A N LEU 27.A O no hydrogen 2.870 N/A THR 21.A N LEU 67.A O no hydrogen 2.891 N/A THR 21.A OG1 THR 26.A OG1 no hydrogen 3.058 N/A CYS 22.A N THR 25.A O no hydrogen 3.124 N/A CYS 22.A SG ASN 65.A O no hydrogen 3.730 N/A THR 25.A N CYS 22.A O no hydrogen 3.278 N/A THR 25.A OG1 CYS 44.A O no hydrogen 3.279 N/A THR 26.A OG1 THR 21.A OG1 no hydrogen 3.058 N/A LEU 27.A N VAL 20.A O no hydrogen 3.003 N/A ASN 28.A N ALA 145.A O no hydrogen 3.128 N/A ASN 28.A ND2 CYS 117.A O no hydrogen 3.220 N/A ASN 28.A ND2 GLY 143.A O no hydrogen 2.925 N/A ASN 28.A ND2 ALA 145.A O no hydrogen 3.183 N/A GLY 29.A N VAL 18.A O no hydrogen 2.651 N/A LEU 30.A N TYR 37.A O no hydrogen 2.653 N/A TRP 31.A N CYS 16.A O no hydrogen 2.869 N/A LEU 32.A N VAL 35.A O no hydrogen 3.024 N/A ASP 33.A N THR 98.A OG1 no hydrogen 2.929 N/A ASP 34.A N ASP 34.A OD1 no hydrogen 2.430 N/A VAL 35.A N LEU 32.A O no hydrogen 2.989 N/A VAL 36.A N LEU 89.A O no hydrogen 2.713 N/A TYR 37.A N LEU 30.A O no hydrogen 2.564 N/A CYS 38.A N LEU 87.A O no hydrogen 3.097 N/A CYS 38.A SG PRO 39.A O no hydrogen 3.361 N/A ARG 40.A N CYS 85.A O no hydrogen 3.394 N/A ARG 40.A NE ASP 187.A OD2 no hydrogen 2.733 N/A ARG 40.A NH2 ASP 187.A OD1 no hydrogen 3.296 N/A VAL 42.A N PRO 39.A O no hydrogen 3.406 N/A ILE 43.A N ARG 40.A O no hydrogen 3.355 N/A CYS 44.A N HIS 41.A O no hydrogen 2.915 N/A CYS 44.A SG ASP 48.A O no hydrogen 3.884 N/A GLU 47.A N THR 45.A OG1 no hydrogen 3.218 N/A ASP 48.A N THR 45.A O no hydrogen 2.698 N/A TYR 54.A OH ASP 187.A O no hydrogen 2.567 N/A LEU 57.A N ASN 53.A O no hydrogen 2.872 N/A LEU 58.A N TYR 54.A O no hydrogen 3.043 N/A ARG 60.A NH1 ASP 56.A O no hydrogen 3.460 N/A LYS 61.A NZ ILE 43.A O no hydrogen 3.564 N/A ASN 65.A N SER 62.A O no hydrogen 3.068 N/A PHE 66.A N ASN 63.A O no hydrogen 2.803 N/A LEU 67.A N THR 21.A O no hydrogen 2.747 N/A GLN 69.A N GLN 19.A O no hydrogen 3.057 N/A ALA 70.A N VAL 73.A O no hydrogen 2.967 N/A VAL 73.A N ALA 70.A O no hydrogen 3.021 N/A GLN 74.A NE2 VAL 68.A O no hydrogen 3.598 N/A LEU 75.A N VAL 68.A O no hydrogen 3.269 N/A ILE 78.A N LYS 90.A O no hydrogen 2.789 N/A GLY 79.A N LYS 90.A O no hydrogen 3.309 N/A SER 81.A N LYS 88.A O no hydrogen 3.251 N/A SER 81.A OG LYS 88.A O no hydrogen 3.217 N/A GLN 83.A N VAL 86.A O no hydrogen 2.936 N/A GLN 83.A NE2 GLU 178.A O no hydrogen 2.895 N/A ASN 84.A ND2 GLU 178.A O no hydrogen 2.945 N/A CYS 85.A N GLY 179.A O no hydrogen 2.977 N/A CYS 85.A SG ASP 187.A OD2 no hydrogen 3.471 N/A VAL 86.A N GLN 83.A O no hydrogen 2.887 N/A LEU 87.A N CYS 38.A O no hydrogen 2.780 N/A LYS 88.A N SER 81.A O no hydrogen 2.817 N/A LEU 89.A N VAL 36.A O no hydrogen 2.764 N/A LYS 90.A N GLY 79.A O no hydrogen 2.649 N/A LYS 90.A NZ ASP 34.A OD2 no hydrogen 2.933 N/A VAL 91.A N ASP 34.A O no hydrogen 2.723 N/A ASP 92.A N ARG 76.A O no hydrogen 3.196 N/A THR 93.A OG1 ASP 92.A OD1 no hydrogen 2.453 N/A ASN 95.A N ASP 33.A O no hydrogen 2.682 N/A ASN 95.A ND2 GLY 15.A O no hydrogen 2.992 N/A ASN 95.A ND2 TRP 31.A O no hydrogen 2.894 N/A LYS 97.A N ASN 95.A OD1 no hydrogen 3.063 N/A THR 98.A N ASN 95.A O no hydrogen 3.160 N/A THR 98.A OG1 ASN 95.A O no hydrogen 2.939 N/A TYR 101.A OH ASP 33.A OD2 no hydrogen 2.971 N/A LYS 102.A N VAL 157.A O no hydrogen 2.883 N/A VAL 104.A N PHE 159.A O no hydrogen 3.152 N/A ARG 105.A NH1 ASP 176.A OD2 no hydrogen 2.586 N/A ARG 105.A NH1 ASN 180.A O no hydrogen 2.973 N/A ARG 105.A NH1 PHE 181.A O no hydrogen 3.361 N/A ARG 105.A NH2 PHE 181.A O no hydrogen 2.822 N/A ILE 106.A N TYR 182.A OH no hydrogen 3.240 N/A GLY 109.A N MET 130.A O no hydrogen 2.804 N/A GLN 110.A N GLN 107.A O no hydrogen 3.193 N/A THR 111.A OG1 ASP 295.A OD1 no hydrogen 3.451 N/A THR 111.A OG1 ASP 295.A OD2 no hydrogen 2.629 N/A PHE 112.A N CYS 128.A O no hydrogen 2.713 N/A SER 113.A N PHE 150.A O no hydrogen 3.060 N/A SER 113.A OG GLN 127.A OE1 no hydrogen 2.826 N/A VAL 114.A N TYR 126.A O no hydrogen 2.631 N/A LEU 115.A N VAL 148.A O no hydrogen 3.319 N/A CYS 117.A N SER 147.A OG no hydrogen 3.083 N/A CYS 117.A SG LEU 115.A O no hydrogen 3.257 N/A TYR 118.A N SER 121.A O no hydrogen 2.895 N/A GLY 120.A N ASN 28.A OD1 no hydrogen 2.849 N/A SER 121.A N TYR 118.A O no hydrogen 2.886 N/A SER 123.A N ALA 116.A O no hydrogen 2.851 N/A SER 123.A OG ALA 116.A O no hydrogen 2.879 N/A TYR 126.A N VAL 114.A O no hydrogen 3.101 N/A TYR 126.A OH SER 139.A O no hydrogen 3.082 N/A CYS 128.A N PHE 112.A O no hydrogen 2.651 N/A MET 130.A N GLN 110.A O no hydrogen 2.922 N/A ARG 131.A N THR 135.A O no hydrogen 3.158 N/A ARG 131.A NH1 ASP 289.A OD1 no hydrogen 3.369 N/A ARG 131.A NH1 GLU 290.A OE2 no hydrogen 2.972 N/A ARG 131.A NH2 THR 198.A O no hydrogen 3.228 N/A ARG 131.A NH2 ASP 289.A OD2 no hydrogen 3.097 N/A ASN 133.A ND2 GLY 195.A O no hydrogen 2.745 N/A PHE 134.A N ARG 131.A O no hydrogen 3.042 N/A THR 135.A N ASN 133.A OD1 no hydrogen 3.111 N/A THR 135.A OG1 ASN 133.A OD1 no hydrogen 2.997 N/A ILE 136.A N HIS 172.A O no hydrogen 3.077 N/A LYS 137.A NZ ASP 197.A OD2 no hydrogen 3.452 N/A GLY 138.A N HIS 172.A ND1 no hydrogen 3.154 N/A SER 139.A N TYR 126.A OH no hydrogen 2.930 N/A LEU 141.A N TYR 118.A OH no hydrogen 2.782 N/A SER 144.A N LEU 141.A O no hydrogen 2.851 N/A SER 144.A OG LEU 141.A O no hydrogen 2.675 N/A GLY 146.A N HIS 163.A O no hydrogen 2.976 N/A SER 147.A N SER 144.A O no hydrogen 3.066 N/A SER 147.A OG SER 144.A O no hydrogen 2.789 N/A GLY 149.A N TYR 161.A O no hydrogen 2.758 N/A PHE 150.A N SER 113.A O no hydrogen 2.959 N/A ASN 151.A N SER 158.A O no hydrogen 2.912 N/A ASN 151.A ND2 THR 111.A O no hydrogen 2.643 N/A ASP 153.A N CYS 156.A O no hydrogen 3.349 N/A CYS 156.A N ASP 153.A O no hydrogen 3.294 N/A CYS 156.A SG LYS 100.A O no hydrogen 3.984 N/A CYS 156.A SG VAL 157.A O no hydrogen 3.927 N/A VAL 157.A N LYS 100.A O no hydrogen 2.738 N/A SER 158.A N ASN 151.A O no hydrogen 2.763 N/A SER 158.A OG ASN 151.A O no hydrogen 3.361 N/A PHE 159.A N LYS 102.A O no hydrogen 2.930 N/A CYS 160.A N GLY 149.A O no hydrogen 2.734 N/A CYS 160.A SG GLY 149.A O no hydrogen 3.435 N/A TYR 161.A N GLY 149.A O no hydrogen 3.168 N/A TYR 161.A OH HIS 163.A ND1 no hydrogen 3.292 N/A MET 162.A N THR 175.A O no hydrogen 2.792 N/A HIS 163.A N SER 147.A O no hydrogen 2.790 N/A HIS 163.A ND1 TYR 161.A OH no hydrogen 3.292 N/A HIS 164.A N ALA 173.A O no hydrogen 3.001 N/A HIS 164.A ND1 MET 162.A O no hydrogen 3.235 N/A HIS 164.A NE2 CYS 85.A O no hydrogen 3.172 N/A MET 165.A N ALA 173.A O no hydrogen 3.168 N/A LEU 167.A N VAL 171.A O no hydrogen 2.905 N/A GLY 170.A N LEU 167.A O no hydrogen 2.986 N/A HIS 172.A N ILE 136.A O no hydrogen 2.864 N/A ALA 173.A N MET 165.A O no hydrogen 2.861 N/A THR 175.A N MET 162.A O no hydrogen 3.180 N/A THR 175.A OG1 ASP 176.A O no hydrogen 3.067 N/A ASP 176.A N ASN 180.A O no hydrogen 3.031 N/A GLY 179.A N ASP 176.A O no hydrogen 2.886 N/A ASN 180.A N ASP 176.A OD1 no hydrogen 3.077 N/A TYR 182.A N GLY 174.A O no hydrogen 2.997 N/A TYR 182.A OH CYS 160.A O no hydrogen 2.459 N/A PHE 185.A N GLY 183.A O no hydrogen 2.873 N/A VAL 186.A N GLN 192.A OE1 no hydrogen 2.464 N/A GLN 192.A NE2 ARG 188.A O no hydrogen 3.503 N/A THR 199.A N ASN 238.A O no hydrogen 3.154 N/A ILE 200.A N ASP 289.A OD2 no hydrogen 3.121 N/A THR 201.A OG1 GLU 240.A O no hydrogen 2.772 N/A ASN 203.A N ILE 200.A O no hydrogen 2.849 N/A ASN 203.A ND2 GLY 109.A O no hydrogen 3.120 N/A ASN 203.A ND2 ASP 289.A O no hydrogen 3.048 N/A VAL 204.A N ILE 200.A O no hydrogen 3.234 N/A LEU 205.A N THR 201.A O no hydrogen 2.898 N/A ALA 206.A N VAL 202.A O no hydrogen 2.815 N/A TRP 207.A N ASN 203.A O no hydrogen 2.830 N/A LEU 208.A N VAL 204.A O no hydrogen 2.695 N/A TYR 209.A N LEU 205.A O no hydrogen 2.915 N/A TYR 209.A OH ILE 259.A O no hydrogen 2.702 N/A ALA 210.A N ALA 206.A O no hydrogen 2.890 N/A ALA 211.A N TRP 207.A O no hydrogen 2.754 N/A VAL 212.A N LEU 208.A O no hydrogen 2.966 N/A ILE 213.A N TYR 209.A O no hydrogen 2.848 N/A ASN 214.A N ALA 210.A O no hydrogen 3.155 N/A ASN 214.A N ALA 211.A O no hydrogen 3.001 N/A ASN 214.A ND2 GLY 2.A O no hydrogen 3.303 N/A GLY 215.A N VAL 212.A O no hydrogen 2.782 N/A ASP 216.A N ALA 211.A O no hydrogen 2.976 N/A TRP 218.A NE1 THR 280.A O no hydrogen 2.871 N/A LEU 220.A N ARG 217.A O no hydrogen 3.161 N/A PHE 223.A N ASN 221.A OD1 no hydrogen 3.339 N/A THR 225.A N THR 224.A OG1 no hydrogen 2.680 N/A THR 225.A OG1 THR 226.A O no hydrogen 3.302 N/A ASP 229.A N THR 226.A OG1 no hydrogen 2.872 N/A PHE 230.A N THR 226.A O no hydrogen 2.765 N/A ASN 231.A N LEU 227.A O no hydrogen 2.627 N/A LEU 232.A N ASN 228.A O no hydrogen 3.000 N/A VAL 233.A N ASP 229.A O no hydrogen 3.430 N/A ALA 234.A N PHE 230.A O no hydrogen 2.800 N/A MET 235.A N ASN 231.A O no hydrogen 2.860 N/A LYS 236.A NZ TYR 237.A OH no hydrogen 3.266 N/A TYR 237.A N VAL 233.A O no hydrogen 3.348 N/A ASN 238.A N MET 235.A O no hydrogen 3.316 N/A TYR 239.A N ALA 234.A O no hydrogen 2.808 N/A GLU 240.A N THR 199.A O no hydrogen 3.104 N/A HIS 246.A N THR 243.A OG1 no hydrogen 3.290 N/A VAL 247.A N THR 243.A O no hydrogen 3.136 N/A ASP 248.A N GLN 244.A O no hydrogen 2.805 N/A ILE 249.A N ASP 245.A O no hydrogen 2.667 N/A LEU 250.A N HIS 246.A O no hydrogen 2.687 N/A GLY 251.A N ASP 248.A O no hydrogen 2.881 N/A SER 254.A N LEU 250.A O no hydrogen 2.795 N/A SER 254.A OG ILE 259.A O no hydrogen 2.774 N/A ALA 255.A N GLY 251.A O no hydrogen 2.955 N/A ALA 255.A N PRO 252.A O no hydrogen 2.884 N/A GLN 256.A N PRO 252.A O no hydrogen 3.004 N/A GLN 256.A NE2 CYS 300.A O no hydrogen 3.366 N/A THR 257.A N LEU 253.A O no hydrogen 3.375 N/A THR 257.A OG1 LEU 253.A O no hydrogen 3.396 N/A THR 257.A OG1 SER 254.A O no hydrogen 3.498 N/A GLY 258.A N ALA 255.A O no hydrogen 3.313 N/A ILE 259.A N SER 254.A O no hydrogen 3.121 N/A ILE 259.A N THR 257.A OG1 no hydrogen 3.196 N/A MET 264.A N ALA 260.A O no hydrogen 3.076 N/A CYS 265.A N VAL 261.A O no hydrogen 2.969 N/A CYS 265.A SG VAL 261.A O no hydrogen 3.826 N/A ALA 266.A N LEU 262.A O no hydrogen 3.137 N/A SER 267.A N ASP 263.A O no hydrogen 3.196 N/A SER 267.A OG PHE 219.A O no hydrogen 3.303 N/A LEU 268.A N MET 264.A O no hydrogen 2.848 N/A LYS 269.A N CYS 265.A O no hydrogen 2.631 N/A LYS 269.A NZ THR 225.A OG1 no hydrogen 2.817 N/A GLU 270.A N ALA 266.A O no hydrogen 3.013 N/A LEU 271.A N SER 267.A O no hydrogen 2.888 N/A LEU 272.A N LEU 268.A O no hydrogen 2.870 N/A GLN 273.A N LYS 269.A O no hydrogen 3.088 N/A ASN 274.A N GLU 270.A O no hydrogen 2.899 N/A GLY 275.A N LEU 271.A O no hydrogen 2.955 N/A ARG 279.A N MET 276.A O no hydrogen 3.092 N/A ARG 279.A NH2 MET 276.A O no hydrogen 3.416 N/A ILE 281.A N SER 284.A O no hydrogen 2.950 N/A LEU 282.A N ASP 216.A OD2 no hydrogen 2.980 N/A SER 284.A N ILE 281.A O no hydrogen 2.847 N/A SER 284.A OG LEU 286.A O no hydrogen 2.784 N/A LEU 286.A N SER 284.A OG no hydrogen 3.002 N/A THR 292.A N ASP 295.A OD2 no hydrogen 2.808 N/A ASP 295.A N THR 292.A OG1 no hydrogen 2.753 N/A VAL 296.A N THR 292.A O no hydrogen 3.008 N/A VAL 297.A N PRO 293.A O no hydrogen 3.127 N/A ARG 298.A N PHE 294.A O no hydrogen 3.101 N/A GLN 299.A N VAL 296.A O no hydrogen 3.258 N/A GLN 299.A NE2 ARG 4.A O no hydrogen 2.905 N/A CYS 300.A N VAL 297.A O no hydrogen 3.259 N/A CYS 300.A SG ASN 214.A OD1 no hydrogen 3.863 N/A CYS 300.A SG GLN 299.A O no hydrogen 3.089 N/A THR 303.A OG1 HIS 302.A O no hydrogen 2.895 N/A