Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8dtm_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): CYS 8.A SG GLU 22.A O no hydrogen 3.752 N/A MET 11.A N HIS 32.A O no hydrogen 2.853 N/A ILE 13.A N GLN 34.A O no hydrogen 2.861 N/A HIS 21.A N THR 18.A O no hydrogen 3.313 N/A GLU 22.A N ARG 19.A O no hydrogen 2.917 N/A GLU 24.A N HIS 21.A O no hydrogen 3.302 N/A SER 27.A N GLU 6.A O no hydrogen 2.733 N/A SER 27.A OG LYS 53.A O no hydrogen 3.244 N/A ILE 29.A N MET 56.A O no hydrogen 3.050 N/A GLU 30.A N CYS 8.A O no hydrogen 2.657 N/A HIS 32.A NE2 ASP 12.A OD1 no hydrogen 2.951 N/A LEU 33.A N TYR 60.A O no hydrogen 3.093 N/A GLN 34.A N MET 11.A O no hydrogen 2.963 N/A GLN 34.A NE2 TYR 60.A OH no hydrogen 3.167 N/A ILE 35.A N LEU 62.A O no hydrogen 2.900 N/A LEU 36.A N ILE 13.A O no hydrogen 2.973 N/A LEU 37.A N PHE 64.A O no hydrogen 3.038 N/A MET 38.A N ARG 65.A O no hydrogen 3.171 N/A THR 41.A OG1 TYR 67.A O no hydrogen 2.132 N/A ARG 42.A N ASP 45.A OD2 no hydrogen 2.571 N/A ARG 42.A NE GLU 44.A OE1 no hydrogen 2.435 N/A ASP 45.A N ARG 42.A O no hydrogen 2.775 N/A ASP 48.A N ASP 48.A OD1 no hydrogen 2.513 N/A PHE 51.A N LEU 75.A O no hydrogen 3.183 N/A ILE 55.A N SER 27.A O no hydrogen 2.890 N/A ILE 57.A N VAL 81.A O no hydrogen 3.074 N/A THR 58.A N ILE 29.A O no hydrogen 3.322 N/A THR 58.A OG1 ILE 29.A O no hydrogen 3.202 N/A LEU 61.A N ALA 92.A O no hydrogen 3.311 N/A LEU 62.A N LEU 33.A O no hydrogen 2.930 N/A LEU 63.A N VAL 94.A O no hydrogen 2.897 N/A PHE 64.A N ILE 35.A O no hydrogen 2.987 N/A ARG 65.A NE GLU 97.A OE1 no hydrogen 2.968 N/A ARG 65.A NH2 GLU 97.A OE1 no hydrogen 3.547 N/A TYR 67.A N MET 38.A O no hydrogen 3.065 N/A SER 71.A OG GLU 103.A O no hydrogen 3.309 N/A LEU 72.A N LEU 104.A O no hydrogen 3.078 N/A LYS 73.A N SER 71.A OG no hydrogen 3.381 N/A LEU 75.A N LEU 72.A O no hydrogen 3.125 N/A PHE 76.A N LEU 72.A O no hydrogen 3.080 N/A ASN 78.A ND2 PRO 52.A O no hydrogen 2.310 N/A THR 80.A N ILE 55.A O no hydrogen 2.898 N/A THR 80.A OG1 ASN 78.A O no hydrogen 3.392 N/A VAL 81.A N ILE 55.A O no hydrogen 3.469 N/A ILE 82.A N ASN 111.A O no hydrogen 3.299 N/A ARG 83.A N ILE 57.A O no hydrogen 2.925 N/A ARG 83.A NH1 CYS 216.A O no hydrogen 3.368 N/A ARG 83.A NH2 ARG 217.A O no hydrogen 2.983 N/A GLY 84.A N THR 58.A O no hydrogen 2.385 N/A SER 85.A N THR 58.A O no hydrogen 3.113 N/A ARG 86.A NH1 ASP 59.A OD2 no hydrogen 3.174 N/A PHE 88.A N TYR 91.A O no hydrogen 3.077 N/A ALA 92.A N SER 116.A O no hydrogen 2.712 N/A VAL 94.A N LEU 61.A O no hydrogen 2.951 N/A ILE 95.A N ARG 118.A O no hydrogen 2.896 N/A PHE 96.A N LEU 63.A O no hydrogen 2.985 N/A GLU 97.A N GLU 120.A O no hydrogen 3.173 N/A MET 98.A N ASN 122.A OD1 no hydrogen 2.793 N/A LYS 102.A N GLU 70.A O no hydrogen 2.815 N/A TYR 107.A N GLY 105.A O no hydrogen 2.802 N/A ASN 108.A ND2 PRO 77.A O no hydrogen 2.709 N/A LEU 109.A N LEU 106.A O no hydrogen 3.170 N/A MET 110.A N THR 80.A O no hydrogen 2.985 N/A ASN 111.A N THR 80.A O no hydrogen 3.463 N/A THR 113.A N ILE 82.A O no hydrogen 3.234 N/A THR 113.A OG1 ASN 111.A OD1 no hydrogen 3.146 N/A ARG 114.A NH1 SER 85.A O no hydrogen 2.361 N/A SER 116.A OG ASP 142.A OD2 no hydrogen 3.000 N/A ARG 118.A N LEU 93.A O no hydrogen 2.923 N/A ILE 119.A N TYR 144.A O no hydrogen 3.287 N/A GLU 120.A N ILE 95.A O no hydrogen 2.943 N/A ASN 122.A ND2 ILE 95.A O no hydrogen 3.682 N/A LEU 125.A N ASN 122.A O no hydrogen 3.256 N/A CYS 126.A N LYS 102.A O no hydrogen 2.554 N/A TYR 127.A OH VAL 158.A O no hydrogen 2.730 N/A THR 130.A OG1 THR 130.A O no hydrogen 2.305 N/A THR 130.A OG1 GLU 168.A O no hydrogen 3.275 N/A THR 130.A OG1 CYS 170.A O no hydrogen 3.108 N/A ASP 132.A N GLN 177.A OE1 no hydrogen 2.932 N/A SER 134.A OG ASP 132.A OD1 no hydrogen 2.414 N/A ARG 135.A N ASP 132.A O no hydrogen 3.140 N/A ILE 136.A N TRP 133.A O no hydrogen 3.361 N/A LEU 137.A N TRP 133.A O no hydrogen 3.094 N/A ASN 143.A N VAL 140.A O no hydrogen 3.440 N/A TYR 144.A N VAL 117.A O no hydrogen 3.107 N/A LYS 149.A N ASN 122.A O no hydrogen 3.074 N/A CYS 155.A SG LEU 125.A O no hydrogen 3.940 N/A VAL 158.A N TYR 127.A OH no hydrogen 3.168 N/A CYS 161.A SG ARG 169.A O no hydrogen 3.712 N/A THR 164.A N VAL 167.A O no hydrogen 3.206 N/A CYS 170.A N THR 130.A O no hydrogen 2.704 N/A CYS 170.A SG THR 130.A OG1 no hydrogen 2.574 N/A TRP 171.A N HIS 175.A O no hydrogen 3.027 N/A THR 172.A N HIS 175.A O no hydrogen 3.079 N/A THR 172.A OG1 HIS 175.A ND1 no hydrogen 3.045 N/A HIS 175.A ND1 THR 172.A OG1 no hydrogen 3.045 N/A CYS 176.A SG ARG 169.A O no hydrogen 3.891 N/A GLN 177.A NE2 ASP 132.A O no hydrogen 3.361 N/A LYS 178.A NZ CYS 189.A O no hydrogen 3.512 N/A CYS 184.A SG GLY 188.A O no hydrogen 3.747 N/A LYS 185.A NZ ILE 183.A O no hydrogen 3.216 N/A CYS 189.A SG THR 190.A O no hydrogen 3.745 N/A THR 190.A N LEU 194.A O no hydrogen 3.239 N/A GLY 193.A N THR 190.A O no hydrogen 3.280 N/A CYS 196.A N GLY 188.A O no hydrogen 3.094 N/A CYS 196.A SG GLY 188.A O no hydrogen 3.129 N/A LYS 198.A NZ GLU 199.A OE2 no hydrogen 3.544 N/A SER 205.A N LYS 212.A O no hydrogen 3.069 N/A SER 205.A OG LYS 212.A O no hydrogen 3.271 N/A THR 211.A OG1 GLY 223.A O no hydrogen 3.116 N/A CYS 213.A SG PRO 210.A O no hydrogen 3.431 N/A ARG 217.A N GLU 199.A O no hydrogen 2.761 N/A LEU 221.A N GLN 224.A O no hydrogen 3.196 N/A CYS 225.A SG PRO 210.A O no hydrogen 3.953 N/A VAL 226.A N PHE 219.A O no hydrogen 3.200 N/A CYS 229.A SG HIS 235.A ND1 no hydrogen 3.019 N/A TYR 233.A N PRO 230.A O no hydrogen 3.083 N/A TYR 234.A N VAL 242.A O no hydrogen 2.898 N/A HIS 235.A N ASN 264.A O no hydrogen 3.304 N/A PHE 236.A N ARG 240.A O no hydrogen 2.865 N/A TRP 239.A N PHE 236.A O no hydrogen 3.058 N/A TRP 239.A NE1 GLU 30.A OE2 no hydrogen 2.997 N/A ARG 240.A N PHE 236.A O no hydrogen 2.992 N/A ARG 240.A NE GLU 30.A OE2 no hydrogen 2.908 N/A ARG 240.A NH2 GLU 30.A OE1 no hydrogen 3.018 N/A ARG 240.A NH2 GLU 30.A OE2 no hydrogen 2.662 N/A CYS 241.A N TYR 220.A O no hydrogen 3.322 N/A CYS 241.A SG TYR 220.A O no hydrogen 3.737 N/A VAL 242.A N TYR 234.A O no hydrogen 2.934 N/A PHE 246.A N ASN 243.A OD1 no hydrogen 2.962 N/A GLN 248.A N PHE 244.A O no hydrogen 2.937 N/A ASP 249.A N SER 245.A O no hydrogen 2.858 N/A LEU 250.A N PHE 246.A O no hydrogen 2.919 N/A HIS 251.A N CYS 247.A O no hydrogen 2.933 N/A PHE 252.A N GLN 248.A O no hydrogen 2.889 N/A LYS 253.A N ASP 249.A O no hydrogen 2.899 N/A CYS 254.A N HIS 251.A O no hydrogen 3.341 N/A CYS 254.A SG CYS 256.A O no hydrogen 3.171 N/A ARG 255.A N PHE 252.A O no hydrogen 2.885 N/A ARG 255.A NH1 GLN 258.A OE1 no hydrogen 2.892 N/A VAL 260.A N ILE 267.A O no hydrogen 2.857 N/A ILE 261.A N LEU 281.A O no hydrogen 2.885 N/A HIS 262.A N LYS 265.A O no hydrogen 2.958 N/A CYS 266.A N HIS 235.A O no hydrogen 3.052 N/A ILE 267.A N VAL 260.A O no hydrogen 2.803 N/A TYR 274.A N PRO 271.A O no hydrogen 3.322 N/A THR 275.A N THR 284.A O no hydrogen 2.903 N/A ASN 277.A N MET 282.A O no hydrogen 3.190 N/A SER 279.A N ASN 277.A OD1 no hydrogen 3.096 N/A SER 279.A OG ASN 280.A OD1 no hydrogen 2.886 N/A LEU 281.A N ASN 277.A O no hydrogen 3.106 N/A CYS 283.A N ILE 261.A O no hydrogen 3.062 N/A CYS 283.A SG ILE 261.A O no hydrogen 3.960 N/A THR 284.A N THR 275.A O no hydrogen 2.909 N/A CYS 286.A SG GLY 288.A O no hydrogen 3.413 N/A LYS 292.A NZ ARG 313.A O no hydrogen 3.303 N/A CYS 294.A N VAL 317.A O no hydrogen 3.002 N/A CYS 294.A SG LYS 292.A O no hydrogen 3.214 N/A GLU 300.A N LEU 297.A O no hydrogen 3.249 N/A LYS 301.A NZ SER 308.A OG no hydrogen 3.401 N/A ILE 303.A N ILE 323.A O no hydrogen 2.867 N/A SER 305.A OG ASP 304.A OD1 no hydrogen 3.156 N/A SER 308.A OG THR 302.A O no hydrogen 3.066 N/A ALA 309.A N SER 305.A O no hydrogen 3.401 N/A GLN 310.A N THR 307.A O no hydrogen 3.185 N/A LEU 312.A N ALA 309.A O no hydrogen 3.135 N/A ARG 313.A N GLN 310.A O no hydrogen 3.113 N/A CYS 315.A N LEU 312.A O no hydrogen 3.163 N/A CYS 315.A SG LEU 312.A O no hydrogen 3.515 N/A THR 316.A N LYS 292.A O no hydrogen 3.360 N/A ILE 318.A N GLU 343.A O no hydrogen 3.017 N/A ASN 319.A N CYS 294.A O no hydrogen 3.285 N/A SER 321.A OG PHE 347.A O no hydrogen 2.262 N/A LEU 322.A N PHE 347.A O no hydrogen 3.115 N/A ILE 323.A N LYS 301.A O no hydrogen 2.888 N/A ILE 324.A N LYS 349.A O no hydrogen 2.847 N/A ASN 325.A N ILE 303.A O no hydrogen 3.200 N/A GLU 333.A N ASN 329.A O no hydrogen 3.038 N/A ALA 336.A N ALA 332.A O no hydrogen 3.292 N/A ASN 337.A N GLU 333.A O no hydrogen 2.942 N/A LEU 338.A N LEU 334.A O no hydrogen 2.877 N/A ILE 341.A N LEU 338.A O no hydrogen 3.431 N/A GLU 342.A N THR 316.A O no hydrogen 2.482 N/A GLU 343.A N THR 316.A O no hydrogen 3.328 N/A ILE 344.A N LEU 367.A O no hydrogen 3.046 N/A SER 345.A N ILE 318.A O no hydrogen 2.815 N/A SER 345.A OG ILE 318.A O no hydrogen 2.995 N/A SER 345.A OG ASN 319.A OD1 no hydrogen 2.798 N/A GLY 346.A N GLY 320.A O no hydrogen 2.566 N/A PHE 347.A N SER 321.A OG no hydrogen 3.355 N/A LEU 348.A N SER 379.A O no hydrogen 2.898 N/A LYS 349.A N LEU 322.A O no hydrogen 2.934 N/A LYS 349.A NZ GLU 374.A OE1 no hydrogen 2.463 N/A ILE 350.A N TYR 381.A O no hydrogen 2.841 N/A ARG 351.A N ILE 324.A O no hydrogen 2.938 N/A ARG 352.A N LEU 383.A O no hydrogen 2.848 N/A SER 353.A OG SER 353.A O no hydrogen 2.462 N/A SER 353.A OG ASN 385.A OD1 no hydrogen 2.785 N/A SER 358.A OG GLN 390.A O no hydrogen 2.421 N/A SER 358.A OG GLN 390.A OE1 no hydrogen 3.278 N/A LEU 359.A N GLN 390.A O no hydrogen 3.201 N/A PHE 362.A N LEU 359.A O no hydrogen 3.319 N/A ARG 363.A NE GLU 335.A OE2 no hydrogen 3.062 N/A ARG 363.A NH2 GLU 335.A OE2 no hydrogen 2.653 N/A LYS 364.A NZ GLY 339.A O no hydrogen 3.467 N/A LEU 365.A N PHE 362.A O no hydrogen 3.453 N/A ILE 368.A N THR 400.A O no hydrogen 3.026 N/A ARG 369.A N ILE 344.A O no hydrogen 2.747 N/A GLU 371.A N SER 345.A O no hydrogen 3.054 N/A GLU 374.A N TYR 378.A O no hydrogen 3.388 N/A TYR 378.A N GLU 374.A O no hydrogen 3.406 N/A TYR 378.A OH ASP 436.A OD1 no hydrogen 3.031 N/A SER 379.A N LYS 405.A O no hydrogen 2.891 N/A SER 379.A OG GLN 403.A O no hydrogen 2.933 N/A SER 379.A OG LYS 405.A O no hydrogen 3.180 N/A PHE 380.A N LYS 405.A O no hydrogen 3.358 N/A TYR 381.A N LEU 348.A O no hydrogen 2.916 N/A ALA 382.A N PHE 407.A O no hydrogen 2.813 N/A LEU 383.A N ILE 350.A O no hydrogen 2.944 N/A ASP 384.A N HIS 409.A O no hydrogen 2.983 N/A ASN 385.A ND2 ILE 350.A O no hydrogen 3.435 N/A ASN 385.A ND2 ASN 411.A OD1 no hydrogen 3.007 N/A ASN 387.A ND2 TYR 354.A O no hydrogen 2.884 N/A ARG 389.A N VAL 357.A O no hydrogen 3.015 N/A TRP 392.A NE1 PHE 362.A O no hydrogen 3.174 N/A LYS 396.A N ASP 393.A O no hydrogen 2.964 N/A HIS 397.A N ASP 393.A O no hydrogen 2.831 N/A HIS 397.A NE2 LEU 365.A O no hydrogen 2.710 N/A LEU 399.A N ASN 398.A OD1 no hydrogen 2.769 N/A THR 400.A OG1 LEU 399.A O no hydrogen 2.771 N/A THR 402.A N ILE 368.A O no hydrogen 3.054 N/A THR 402.A OG1 ILE 368.A O no hydrogen 3.551 N/A GLN 403.A N ARG 369.A O no hydrogen 3.162 N/A LYS 405.A N ASN 377.A O no hydrogen 2.931 N/A LYS 405.A NZ GLY 376.A O no hydrogen 2.546 N/A LYS 405.A NZ ASN 377.A O no hydrogen 2.689 N/A LEU 406.A N GLN 432.A OE1 no hydrogen 2.364 N/A HIS 409.A N ALA 382.A O no hydrogen 3.024 N/A ASN 411.A N ASN 442.A OD1 no hydrogen 3.289 N/A ASN 411.A ND2 ASN 442.A OD1 no hydrogen 3.652 N/A LYS 413.A NZ ASN 387.A OD1 no hydrogen 3.318 N/A GLU 418.A N CYS 415.A O no hydrogen 3.097 N/A HIS 420.A N LEU 416.A O no hydrogen 2.927 N/A LYS 421.A N SER 417.A O no hydrogen 2.868 N/A LYS 421.A NZ GLU 424.A OE1 no hydrogen 3.413 N/A MET 422.A N GLU 418.A O no hydrogen 2.905 N/A GLU 423.A N ILE 419.A O no hydrogen 2.911 N/A GLU 424.A N HIS 420.A O no hydrogen 2.906 N/A VAL 425.A N LYS 421.A O no hydrogen 2.895 N/A SER 426.A N MET 422.A O no hydrogen 2.901 N/A SER 426.A OG MET 422.A O no hydrogen 3.169 N/A SER 426.A OG THR 428.A OG1 no hydrogen 2.920 N/A GLY 427.A N GLU 423.A O no hydrogen 3.274 N/A THR 428.A N SER 426.A OG no hydrogen 3.341 N/A THR 428.A OG1 SER 426.A OG no hydrogen 2.920 N/A ARG 431.A N THR 428.A O no hydrogen 3.316 N/A ARG 431.A NH1 GLY 404.A O no hydrogen 2.841 N/A ARG 431.A NH2 ILE 401.A O no hydrogen 2.582 N/A GLN 432.A NE2 GLU 423.A OE2 no hydrogen 2.628 N/A GLU 433.A N ASP 436.A OD2 no hydrogen 3.085 N/A ALA 438.A N PHE 408.A O no hydrogen 3.075 N/A THR 441.A OG1 THR 441.A O no hydrogen 2.388 N/A ASN 442.A ND2 ALA 438.A O no hydrogen 2.625 N/A GLY 443.A N ASN 411.A O no hydrogen 3.201 N/A ASP 444.A N PRO 412.A O no hydrogen 2.425 N/A