Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8dv6_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 1.A N GLY 150.A O no hydrogen 3.399 N/A ARG 2.A NE GLU 44.A OE2 no hydrogen 3.133 N/A ARG 2.A NH1 ASP 155.A OD2 no hydrogen 3.398 N/A ARG 2.A NH2 ASP 155.A OD2 no hydrogen 3.339 N/A ILE 4.A N ARG 2.A O no hydrogen 2.779 N/A ARG 9.A N SER 7.A O no hydrogen 2.925 N/A ARG 9.A NE THR 32.A OG1 no hydrogen 3.070 N/A ARG 9.A NH1 GLU 377.A OE2 no hydrogen 2.722 N/A ARG 9.A NH2 THR 32.A OG1 no hydrogen 3.344 N/A ARG 9.A NH2 GLU 377.A OE1 no hydrogen 2.768 N/A ARG 9.A NH2 GLU 377.A OE2 no hydrogen 3.325 N/A ASP 10.A N CYS 30.A O no hydrogen 3.049 N/A VAL 12.A N THR 32.A O no hydrogen 2.894 N/A GLY 14.A N MET 34.A O no hydrogen 3.245 N/A SER 16.A OG GLN 36.A OE1 no hydrogen 3.005 N/A THR 19.A N GLY 17.A O no hydrogen 2.555 N/A THR 19.A OG1 GLY 18.A O no hydrogen 2.413 N/A TRP 20.A N GLY 18.A O no hydrogen 2.649 N/A VAL 21.A N LEU 293.A O no hydrogen 2.942 N/A VAL 23.A N CYS 291.A O no hydrogen 2.902 N/A LEU 25.A N LEU 289.A O no hydrogen 2.883 N/A HIS 27.A NE2 THR 48.A OG1 no hydrogen 2.657 N/A GLY 29.A N GLU 26.A O no hydrogen 3.033 N/A CYS 30.A N ASN 8.A O no hydrogen 3.083 N/A CYS 30.A SG ILE 43.A O no hydrogen 3.358 N/A VAL 31.A N ILE 43.A O no hydrogen 2.925 N/A THR 32.A N ASP 10.A O no hydrogen 2.818 N/A THR 32.A OG1 ASP 42.A OD1 no hydrogen 2.628 N/A VAL 33.A N VAL 41.A O no hydrogen 2.851 N/A MET 34.A N VAL 12.A O no hydrogen 2.958 N/A LYS 38.A N ALA 35.A O no hydrogen 3.195 N/A LYS 38.A NZ MET 295.A O no hydrogen 2.913 N/A LYS 38.A NZ LEU 298.A O no hydrogen 2.725 N/A THR 40.A OG1 ILE 359.A O no hydrogen 2.624 N/A VAL 41.A N VAL 33.A O no hydrogen 2.986 N/A ASP 42.A N SER 142.A O no hydrogen 2.860 N/A ILE 43.A N VAL 31.A O no hydrogen 2.909 N/A GLU 44.A N MET 140.A O no hydrogen 2.953 N/A VAL 46.A N ARG 138.A O no hydrogen 2.938 N/A THR 48.A OG1 HIS 27.A NE2 no hydrogen 2.657 N/A THR 49.A N GLU 136.A O no hydrogen 2.723 N/A THR 49.A OG1 GLU 136.A O no hydrogen 3.380 N/A VAL 50.A N GLY 282.A O no hydrogen 2.879 N/A SER 51.A N ASN 134.A O no hydrogen 3.199 N/A VAL 56.A N GLY 127.A O no hydrogen 2.918 N/A ARG 57.A NH1 TYR 59.A OH no hydrogen 3.271 N/A SER 58.A N HIS 226.A O no hydrogen 2.872 N/A SER 58.A OG THR 126.A OG1 no hydrogen 3.290 N/A TYR 59.A N MET 125.A O no hydrogen 2.911 N/A TYR 59.A OH PHE 218.A O no hydrogen 3.076 N/A CYS 60.A N PRO 224.A O no hydrogen 2.869 N/A CYS 60.A SG GLU 62.A O no hydrogen 3.482 N/A CYS 60.A SG LYS 123.A O no hydrogen 3.717 N/A TYR 61.A N LYS 123.A O no hydrogen 2.933 N/A GLU 62.A N LYS 123.A O no hydrogen 2.957 N/A SER 64.A N ALA 120.A O no hydrogen 2.915 N/A SER 66.A N LYS 118.A O no hydrogen 3.161 N/A ALA 69.A N CYS 116.A O no hydrogen 2.903 N/A SER 70.A OG THR 115.A OG1 no hydrogen 3.079 N/A ASP 71.A N VAL 114.A O no hydrogen 2.918 N/A ARG 73.A N SER 112.A O no hydrogen 2.879 N/A ARG 73.A NH1 ASP 71.A OD2 no hydrogen 3.468 N/A ARG 73.A NH1 SER 72.A O no hydrogen 3.283 N/A THR 76.A OG1 PRO 75.A O no hydrogen 2.446 N/A GLN 77.A N CYS 74.A O no hydrogen 3.039 N/A ALA 80.A N SER 112.A OG no hydrogen 3.131 N/A LEU 82.A N GLN 85.A OE1 no hydrogen 2.935 N/A GLN 85.A N LEU 82.A O no hydrogen 3.157 N/A ASP 87.A N LYS 84.A O no hydrogen 3.196 N/A GLN 89.A N ASP 87.A OD1 no hydrogen 3.151 N/A TYR 90.A N ASP 87.A O no hydrogen 3.101 N/A TYR 90.A OH ASP 67.A OD2 no hydrogen 2.440 N/A VAL 91.A N ALA 117.A O no hydrogen 2.868 N/A CYS 92.A SG LYS 84.A O no hydrogen 3.941 N/A LYS 93.A N THR 115.A O no hydrogen 2.889 N/A ARG 94.A NH1 ALA 80.A O no hydrogen 2.416 N/A THR 95.A N LEU 113.A O no hydrogen 2.880 N/A THR 95.A OG1 LEU 96.A O no hydrogen 3.403 N/A VAL 97.A N GLY 111.A O no hydrogen 2.898 N/A ARG 99.A N GLY 109.A O no hydrogen 2.867 N/A ARG 99.A NE ASN 103.A OD1 no hydrogen 3.332 N/A ARG 99.A NH2 ASN 103.A O no hydrogen 3.222 N/A GLY 100.A N ASN 103.A OD1 no hydrogen 2.700 N/A TRP 101.A NE1 GLY 106.A O no hydrogen 2.588 N/A ASN 103.A ND2 ASP 98.A O no hydrogen 3.531 N/A GLY 104.A N TRP 101.A O no hydrogen 3.444 N/A GLY 109.A N ARG 99.A O no hydrogen 2.934 N/A LYS 110.A NZ ASP 98.A OD1 no hydrogen 2.796 N/A GLY 111.A N VAL 97.A O no hydrogen 2.876 N/A SER 112.A N ARG 73.A O no hydrogen 2.943 N/A SER 112.A OG GLU 79.A OE1 no hydrogen 3.222 N/A LEU 113.A N THR 95.A O no hydrogen 2.923 N/A VAL 114.A N ASP 71.A O no hydrogen 2.911 N/A THR 115.A N LYS 93.A O no hydrogen 2.928 N/A THR 115.A OG1 SER 70.A OG no hydrogen 3.079 N/A CYS 116.A N ALA 69.A O no hydrogen 2.880 N/A ALA 117.A N VAL 91.A O no hydrogen 2.940 N/A LYS 118.A N SER 66.A O no hydrogen 2.686 N/A PHE 119.A N GLN 89.A O no hydrogen 3.030 N/A ALA 120.A N SER 64.A O no hydrogen 3.034 N/A CYS 121.A SG GLU 62.A O no hydrogen 3.721 N/A CYS 121.A SG LYS 123.A O no hydrogen 3.432 N/A SER 122.A N GLU 62.A O no hydrogen 2.756 N/A LYS 123.A N GLU 62.A O no hydrogen 2.872 N/A LYS 124.A NZ HIS 226.A NE2 no hydrogen 3.100 N/A MET 125.A N TYR 59.A O no hydrogen 2.726 N/A THR 126.A N THR 205.A O no hydrogen 2.947 N/A THR 126.A OG1 SER 58.A OG no hydrogen 3.290 N/A GLY 127.A N ARG 57.A O no hydrogen 2.974 N/A LYS 128.A N TYR 203.A O no hydrogen 2.890 N/A SER 129.A N ALA 54.A O no hydrogen 2.858 N/A SER 129.A OG ALA 54.A O no hydrogen 2.959 N/A ASN 134.A N GLN 131.A O no hydrogen 3.053 N/A GLU 136.A N THR 49.A O no hydrogen 2.829 N/A TYR 137.A N ILE 169.A O no hydrogen 2.907 N/A ARG 138.A N THR 47.A O no hydrogen 2.943 N/A ILE 139.A N VAL 167.A O no hydrogen 2.919 N/A MET 140.A N GLU 44.A O no hydrogen 2.875 N/A LEU 141.A N ALA 165.A O no hydrogen 2.880 N/A SER 142.A N ASP 42.A O no hydrogen 2.937 N/A HIS 144.A N THR 40.A O no hydrogen 3.093 N/A THR 160.A N GLY 157.A O no hydrogen 2.955 N/A THR 160.A OG1 GLY 157.A O no hydrogen 2.544 N/A ASP 161.A N HIS 158.A O no hydrogen 2.951 N/A ASN 163.A N ASP 161.A O no hydrogen 2.729 N/A ALA 165.A N LEU 141.A O no hydrogen 2.910 N/A VAL 167.A N ILE 139.A O no hydrogen 2.901 N/A ILE 169.A N TYR 137.A O no hydrogen 2.877 N/A THR 170.A OG1 SER 173.A OG no hydrogen 3.364 N/A SER 173.A N THR 170.A O no hydrogen 2.814 N/A ALA 176.A N LEU 188.A O no hydrogen 2.984 N/A ALA 178.A N LEU 186.A O no hydrogen 2.879 N/A LEU 180.A N GLY 184.A O no hydrogen 2.893 N/A GLY 182.A N GLU 162.A OE2 no hydrogen 3.020 N/A PHE 183.A N LEU 180.A O no hydrogen 3.030 N/A GLY 184.A N GLY 181.A O no hydrogen 3.204 N/A SER 185.A N.A LYS 297.A O no hydrogen 2.984 N/A SER 185.A N.B LYS 297.A O no hydrogen 2.982 N/A SER 185.A OG.A ALA 178.A O no hydrogen 2.527 N/A SER 185.A OG.B GLU 177.A OE2 no hydrogen 2.598 N/A LEU 186.A N ALA 178.A O no hydrogen 2.904 N/A GLY 187.A N LYS 294.A O no hydrogen 2.932 N/A LEU 188.A N ALA 176.A O no hydrogen 2.857 N/A ASP 189.A N ARG 292.A O no hydrogen 2.935 N/A GLU 191.A N LYS 290.A O no hydrogen 2.936 N/A ARG 193.A N GLU 191.A OE1 no hydrogen 3.134 N/A GLY 195.A N PRO 192.A O no hydrogen 2.671 N/A SER 199.A OG ASP 197.A OD1 no hydrogen 2.908 N/A TYR 202.A N VAL 213.A O no hydrogen 2.880 N/A TYR 203.A N LYS 128.A O no hydrogen 2.922 N/A TYR 203.A OH GLU 276.A O no hydrogen 3.244 N/A LEU 204.A N TRP 211.A O no hydrogen 2.902 N/A THR 205.A N THR 126.A O no hydrogen 2.891 N/A MET 206.A N LYS 209.A O no hydrogen 2.817 N/A ASN 207.A ND2 GLU 262.A OE2 no hydrogen 2.906 N/A LYS 209.A N MET 206.A O no hydrogen 3.092 N/A TRP 211.A N LEU 204.A O no hydrogen 2.888 N/A LEU 212.A N LEU 273.A O no hydrogen 3.374 N/A VAL 213.A N TYR 202.A O no hydrogen 2.937 N/A LYS 215.A N ASP 200.A O no hydrogen 3.324 N/A LYS 215.A NZ SER 199.A O no hydrogen 3.047 N/A PHE 218.A N HIS 214.A O no hydrogen 3.110 N/A HIS 219.A N LYS 215.A O no hydrogen 2.929 N/A HIS 219.A ND1 LYS 215.A O no hydrogen 2.549 N/A ASP 220.A N GLU 216.A O no hydrogen 3.251 N/A ASP 220.A N TRP 217.A O no hydrogen 3.315 N/A ILE 221.A N PHE 218.A O no hydrogen 3.476 N/A LEU 223.A N ILE 221.A O no hydrogen 3.161 N/A TRP 225.A N ASN 237.A O no hydrogen 3.008 N/A HIS 226.A N SER 58.A O no hydrogen 2.941 N/A THR 231.A N ALA 229.A O no hydrogen 2.850 N/A THR 233.A OG1 PRO 234.A O no hydrogen 3.546 N/A ASN 237.A N TRP 225.A O no hydrogen 2.846 N/A ASN 237.A ND2 TRP 225.A O no hydrogen 3.051 N/A LYS 239.A NZ THR 88.A O no hydrogen 2.842 N/A LYS 239.A NZ TRP 236.A O no hydrogen 2.412 N/A ALA 241.A N ASN 238.A O no hydrogen 3.283 N/A LEU 242.A N LYS 239.A O no hydrogen 3.348 N/A VAL 243.A N LYS 239.A O no hydrogen 3.323 N/A GLU 244.A N VAL 256.A O no hydrogen 2.910 N/A LYS 246.A N THR 254.A O no hydrogen 2.866 N/A HIS 249.A N ASP 247.A OD2 no hydrogen 3.071 N/A HIS 249.A ND1 ASP 247.A OD1 no hydrogen 2.794 N/A GLN 253.A NE2 THR 115.A OG1 no hydrogen 3.201 N/A THR 254.A N LYS 246.A O no hydrogen 2.941 N/A VAL 256.A N GLU 244.A O no hydrogen 2.952 N/A LEU 258.A N LEU 242.A O no hydrogen 2.750 N/A SER 260.A OG GLU 62.A OE1 no hydrogen 3.266 N/A GLN 261.A N TYR 61.A O no hydrogen 2.892 N/A GLN 261.A NE2 GLY 259.A O no hydrogen 3.393 N/A GLU 262.A N SER 260.A OG no hydrogen 3.363 N/A VAL 265.A N GLN 261.A O no hydrogen 3.086 N/A HIS 266.A N GLU 262.A O no hydrogen 2.893 N/A THR 267.A N GLY 263.A O no hydrogen 2.889 N/A THR 267.A OG1 GLY 263.A O no hydrogen 3.017 N/A ALA 268.A N ALA 264.A O no hydrogen 2.898 N/A ALA 275.A N HIS 210.A O no hydrogen 3.271 N/A GLU 276.A N ARG 283.A O no hydrogen 3.054 N/A ARG 283.A N GLU 276.A O no hydrogen 2.920 N/A ARG 283.A NE GLU 276.A OE1 no hydrogen 3.532 N/A LEU 284.A N THR 48.A O no hydrogen 2.888 N/A HIS 288.A ND1 THR 194.A O no hydrogen 2.948 N/A HIS 288.A ND1 GLY 195.A O no hydrogen 2.865 N/A CYS 291.A N VAL 23.A O no hydrogen 2.906 N/A LEU 293.A N VAL 21.A O no hydrogen 2.834 N/A LYS 294.A N GLY 187.A O no hydrogen 2.870 N/A MET 295.A N THR 19.A O no hydrogen 2.582 N/A LYS 297.A NZ ASP 296.A OD2 no hydrogen 3.451 N/A LEU 298.A N MET 295.A O no hydrogen 3.033 N/A ARG 299.A N PHE 183.A O no hydrogen 2.859 N/A VAL 303.A N LYS 301.A O no hydrogen 2.701 N/A TYR 305.A OH LYS 301.A O no hydrogen 2.817 N/A CYS 308.A N LYS 340.A O no hydrogen 2.828 N/A CYS 308.A SG LYS 340.A O no hydrogen 3.238 N/A THR 309.A N ASP 336.A OD2 no hydrogen 3.124 N/A THR 309.A OG1 ASP 336.A OD2 no hydrogen 2.912 N/A ALA 310.A N TYR 332.A OH no hydrogen 3.165 N/A THR 313.A N GLN 331.A O no hydrogen 2.939 N/A THR 313.A OG1 GLN 331.A O no hydrogen 3.417 N/A LYS 316.A NZ HIS 148.A NE2 no hydrogen 3.413 N/A ALA 319.A N THR 327.A O no hydrogen 3.439 N/A THR 321.A N THR 325.A O no hydrogen 3.057 N/A THR 321.A OG1 THR 325.A O no hydrogen 3.374 N/A THR 321.A OG1 THR 325.A OG1 no hydrogen 2.748 N/A HIS 323.A N THR 321.A OG1 no hydrogen 3.337 N/A GLY 324.A N THR 321.A O no hydrogen 3.387 N/A THR 325.A OG1 THR 321.A OG1 no hydrogen 2.748 N/A THR 325.A OG1 GLU 377.A OE2 no hydrogen 2.803 N/A VAL 326.A N LEU 378.A O no hydrogen 2.900 N/A THR 327.A N ALA 319.A O no hydrogen 3.318 N/A THR 327.A OG1 ALA 319.A O no hydrogen 3.513 N/A VAL 328.A N LEU 376.A O no hydrogen 2.924 N/A VAL 330.A N MET 374.A O no hydrogen 2.896 N/A GLN 331.A N THR 313.A O no hydrogen 2.865 N/A TYR 332.A N SER 372.A O no hydrogen 2.878 N/A TYR 332.A OH ASP 336.A OD1 no hydrogen 2.435 N/A VAL 341.A N PRO 363.A O no hydrogen 2.851 N/A GLN 344.A N VAL 388.A O no hydrogen 2.929 N/A GLN 344.A NE2 LEU 352.A O no hydrogen 3.310 N/A ALA 346.A N TYR 386.A O no hydrogen 2.883 N/A GLN 350.A N ASP 348.A OD2 no hydrogen 3.218 N/A THR 351.A N ASP 348.A OD2 no hydrogen 3.339 N/A LEU 352.A N ASP 348.A O no hydrogen 3.066 N/A VAL 355.A N MET 345.A O no hydrogen 3.050 N/A ARG 357.A NE ASP 379.A OD2 no hydrogen 3.220 N/A ARG 357.A NH2 ASP 379.A OD2 no hydrogen 3.535 N/A ILE 359.A N GLU 377.A O no hydrogen 2.974 N/A THR 360.A N GLU 377.A O no hydrogen 3.141 N/A THR 360.A OG1 HIS 144.A ND1 no hydrogen 3.337 N/A ILE 365.A N CYS 339.A O no hydrogen 3.084 N/A GLU 370.A N GLU 370.A OE1 no hydrogen 2.762 N/A SER 372.A N TYR 332.A O no hydrogen 2.908 N/A MET 374.A N VAL 330.A O no hydrogen 2.957 N/A LEU 376.A N VAL 328.A O no hydrogen 2.889 N/A GLU 377.A N THR 360.A OG1 no hydrogen 2.892 N/A LEU 378.A N VAL 326.A O no hydrogen 2.892 N/A ASP 379.A N ARG 357.A O no hydrogen 2.931 N/A GLY 383.A N ARG 402.A O no hydrogen 2.902 N/A SER 385.A N TRP 400.A O no hydrogen 2.894 N/A TYR 386.A N ALA 346.A O no hydrogen 2.882 N/A ILE 387.A N HIS 398.A O no hydrogen 2.854 N/A VAL 388.A N GLN 344.A O no hydrogen 2.908 N/A ILE 389.A N ILE 396.A O no hydrogen 2.955 N/A GLY 390.A N PRO 342.A O no hydrogen 2.926 N/A ILE 396.A N ILE 389.A O no hydrogen 2.917 N/A HIS 398.A N ILE 387.A O no hydrogen 2.915 N/A TRP 400.A N SER 385.A O no hydrogen 2.895 N/A HIS 401.A ND1 ASP 384.A OD1 no hydrogen 2.691 N/A ARG 402.A N GLY 383.A O no hydrogen 2.916 N/A ARG 402.A NH1 ASP 379.A OD1 no hydrogen 2.845 N/A ARG 402.A NH1 PRO 380.A O no hydrogen 2.826 N/A SER 403.A OG SER 405.A OG no hydrogen 3.232 N/A SER 405.A N SER 403.A OG no hydrogen 3.364 N/A SER 405.A OG SER 403.A OG no hydrogen 3.232 N/A