Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8dwn_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 5.A N VAL 79.A O no hydrogen 3.005 N/A ARG 7.A NH1 PRO 85.A O no hydrogen 2.667 N/A ARG 7.A NH2 LYS 82.A O no hydrogen 3.076 N/A ARG 7.A NH2 PRO 85.A O no hydrogen 2.530 N/A LYS 9.A N SER 6.A O no hydrogen 2.924 N/A LYS 9.A NZ ARG 30.A O no hydrogen 2.349 N/A LYS 9.A NZ ASP 31.A O no hydrogen 2.614 N/A ILE 10.A N ARG 7.A O no hydrogen 3.104 N/A THR 11.A N ASN 28.A O no hydrogen 2.869 N/A THR 11.A OG1 ASN 28.A O no hydrogen 3.412 N/A LEU 13.A N GLU 26.A O no hydrogen 2.738 N/A ARG 14.A N GLU 26.A O no hydrogen 3.299 N/A ARG 14.A NH1 GLU 15.A O no hydrogen 3.168 N/A LEU 16.A N VAL 24.A O no hydrogen 2.698 N/A GLY 17.A N VAL 24.A O no hydrogen 3.213 N/A GLY 19.A N GLY 22.A O no hydrogen 2.735 N/A GLY 22.A N GLY 19.A O no hydrogen 3.235 N/A VAL 24.A N GLY 17.A O no hydrogen 2.926 N/A TYR 25.A N VAL 43.A O no hydrogen 2.897 N/A GLU 26.A N ARG 14.A O no hydrogen 2.750 N/A GLY 27.A N VAL 41.A O no hydrogen 2.910 N/A ASN 28.A N THR 11.A O no hydrogen 2.754 N/A ALA 29.A N THR 39.A O no hydrogen 2.921 N/A ARG 30.A N LYS 9.A O no hydrogen 2.887 N/A ASP 31.A N ALA 37.A O no hydrogen 3.019 N/A GLU 36.A N ILE 33.A O no hydrogen 2.850 N/A THR 39.A N ALA 29.A O no hydrogen 2.946 N/A THR 39.A OG1 GLU 36.A OE1 no hydrogen 2.991 N/A ARG 40.A NH2 GLU 26.A OE2 no hydrogen 3.038 N/A VAL 41.A N GLY 27.A O no hydrogen 3.200 N/A ALA 42.A N MET 90.A O no hydrogen 2.876 N/A VAL 43.A N TYR 25.A O no hydrogen 2.741 N/A LYS 44.A N VAL 88.A O no hydrogen 2.701 N/A THR 45.A N MET 23.A O no hydrogen 3.216 N/A THR 45.A OG1 MET 23.A O no hydrogen 2.725 N/A ASN 47.A N PHE 21.A O no hydrogen 2.788 N/A ALA 50.A N ASN 47.A O no hydrogen 3.184 N/A SER 51.A N GLU 54.A OE1 no hydrogen 3.013 N/A SER 51.A OG GLU 54.A OE1 no hydrogen 3.376 N/A GLU 54.A N SER 51.A OG no hydrogen 3.171 N/A ARG 55.A N SER 51.A O no hydrogen 3.153 N/A ARG 55.A NE ALA 50.A O no hydrogen 3.253 N/A ARG 55.A NH2 ALA 50.A O no hydrogen 3.289 N/A ILE 56.A N LEU 52.A O no hydrogen 2.974 N/A GLU 57.A N ARG 53.A O no hydrogen 2.859 N/A PHE 58.A N GLU 54.A O no hydrogen 2.681 N/A LEU 59.A N ARG 55.A O no hydrogen 3.351 N/A ASN 60.A N ILE 56.A O no hydrogen 2.944 N/A GLU 61.A N GLU 57.A O no hydrogen 2.965 N/A ALA 62.A N PHE 58.A O no hydrogen 3.396 N/A SER 63.A N LEU 59.A O no hydrogen 3.070 N/A VAL 64.A N ASN 60.A O no hydrogen 3.136 N/A MET 65.A N GLU 61.A O no hydrogen 3.167 N/A LYS 66.A N ALA 62.A O no hydrogen 3.131 N/A LYS 66.A N SER 63.A O no hydrogen 3.110 N/A GLY 67.A N VAL 64.A O no hydrogen 3.035 N/A PHE 68.A N MET 65.A O no hydrogen 2.946 N/A THR 69.A N TYR 136.A OH no hydrogen 2.943 N/A THR 69.A OG1 THR 69.A O no hydrogen 2.511 N/A HIS 72.A ND1 ASP 132.A OD1 no hydrogen 2.689 N/A VAL 73.A N CYS 70.A O no hydrogen 3.263 N/A VAL 74.A N ILE 162.A O no hydrogen 2.826 N/A ARG 75.A N GLU 91.A OE1 no hydrogen 3.073 N/A LEU 77.A N VAL 89.A O no hydrogen 2.736 N/A GLY 78.A N VAL 89.A O no hydrogen 3.218 N/A VAL 79.A N TRP 3.A O no hydrogen 2.941 N/A VAL 80.A N LEU 87.A O no hydrogen 2.695 N/A SER 81.A N GLU 4.A OE2 no hydrogen 2.849 N/A SER 81.A OG GLU 4.A OE1 no hydrogen 2.474 N/A SER 81.A OG GLU 4.A OE2 no hydrogen 3.254 N/A LEU 87.A N VAL 80.A O no hydrogen 3.004 N/A VAL 88.A N LYS 44.A O no hydrogen 2.922 N/A VAL 89.A N GLY 78.A O no hydrogen 2.860 N/A MET 90.A N ALA 42.A O no hydrogen 2.708 N/A GLU 91.A N ARG 75.A O no hydrogen 3.013 N/A HIS 95.A N VAL 154.A O no hydrogen 2.980 N/A GLY 96.A N MET 93.A O no hydrogen 3.042 N/A LEU 98.A N CYS 152.A O no hydrogen 2.614 N/A SER 100.A N ASP 97.A OD2 no hydrogen 2.845 N/A SER 100.A OG ASP 97.A OD1 no hydrogen 2.753 N/A SER 100.A OG ASP 97.A OD2 no hydrogen 3.006 N/A TYR 101.A N ASP 97.A O no hydrogen 3.059 N/A LEU 102.A N LEU 98.A O no hydrogen 2.870 N/A ARG 103.A N LYS 99.A O no hydrogen 2.979 N/A ARG 103.A NE ALA 208.A O no hydrogen 2.982 N/A ARG 103.A NH2 ALA 208.A O no hydrogen 3.293 N/A SER 104.A N SER 100.A O no hydrogen 3.170 N/A SER 104.A N TYR 101.A O no hydrogen 3.164 N/A SER 104.A OG TYR 101.A O no hydrogen 2.885 N/A LEU 105.A N LEU 102.A O no hydrogen 2.957 N/A ARG 106.A N ARG 103.A O no hydrogen 3.217 N/A ALA 109.A N ARG 106.A O no hydrogen 3.064 N/A ASN 111.A N ASN 111.A OD1 no hydrogen 2.603 N/A ASN 112.A N ALA 109.A O no hydrogen 3.261 N/A ASN 112.A ND2 ARG 106.A O no hydrogen 2.962 N/A GLY 114.A N ASN 112.A OD1 no hydrogen 2.677 N/A THR 119.A N GLU 122.A OE2 no hydrogen 2.853 N/A GLU 122.A N THR 119.A OG1 no hydrogen 2.995 N/A MET 123.A N THR 119.A O no hydrogen 2.855 N/A ILE 124.A N LEU 120.A O no hydrogen 2.970 N/A GLN 125.A N GLN 121.A O no hydrogen 3.023 N/A GLN 125.A NE2 GLU 129.A OE2 no hydrogen 2.614 N/A MET 126.A N GLU 122.A O no hydrogen 3.005 N/A ALA 127.A N MET 123.A O no hydrogen 2.944 N/A ALA 128.A N ILE 124.A O no hydrogen 2.971 N/A GLU 129.A N GLN 125.A O no hydrogen 2.966 N/A ILE 130.A N MET 126.A O no hydrogen 2.983 N/A ALA 131.A N ALA 127.A O no hydrogen 2.933 N/A ASP 132.A N ALA 128.A O no hydrogen 2.716 N/A GLY 133.A N GLU 129.A O no hydrogen 2.936 N/A MET 134.A N ILE 130.A O no hydrogen 2.897 N/A ALA 135.A N ALA 131.A O no hydrogen 2.740 N/A TYR 136.A N ASP 132.A O no hydrogen 2.954 N/A LEU 137.A N GLY 133.A O no hydrogen 2.945 N/A ASN 138.A N MET 134.A O no hydrogen 2.855 N/A ALA 139.A N ALA 135.A O no hydrogen 2.887 N/A LYS 140.A N TYR 136.A O no hydrogen 2.990 N/A LYS 141.A N ASN 138.A O no hydrogen 2.798 N/A PHE 142.A N LEU 137.A O no hydrogen 3.009 N/A HIS 144.A N ASP 193.A OD1 no hydrogen 2.799 N/A ARG 145.A N ASP 193.A OD2 no hydrogen 2.981 N/A ASP 146.A N HIS 144.A ND1 no hydrogen 2.928 N/A ALA 149.A N GLU 203.A OE1 no hydrogen 2.989 N/A ARG 150.A NE TYR 165.A OH no hydrogen 3.085 N/A ARG 150.A NH2 ASP 146.A OD1 no hydrogen 3.110 N/A ARG 150.A NH2 TYR 165.A OH no hydrogen 3.570 N/A ASN 151.A N ALA 148.A O no hydrogen 2.934 N/A ASN 151.A ND2 ASP 146.A O no hydrogen 2.751 N/A CYS 152.A N ALA 149.A O no hydrogen 2.989 N/A CYS 152.A SG ALA 148.A O no hydrogen 3.671 N/A MET 153.A N LYS 161.A O no hydrogen 2.913 N/A VAL 154.A N GLY 96.A O no hydrogen 2.876 N/A ALA 155.A N THR 159.A O no hydrogen 2.827 N/A PHE 158.A N ALA 155.A O no hydrogen 2.759 N/A THR 159.A N ASP 157.A OD1 no hydrogen 3.046 N/A THR 159.A OG1 ASP 157.A OD1 no hydrogen 2.638 N/A THR 159.A OG1 ASP 157.A OD2 no hydrogen 3.172 N/A VAL 160.A N GLU 129.A OE1 no hydrogen 3.002 N/A LYS 161.A N MET 153.A O no hydrogen 2.921 N/A LYS 161.A NZ HIS 71.A O no hydrogen 2.880 N/A LYS 161.A NZ GLU 91.A OE1 no hydrogen 3.548 N/A LYS 161.A NZ GLU 91.A OE2 no hydrogen 2.602 N/A ILE 162.A N HIS 72.A O no hydrogen 2.858 N/A GLY 163.A N ASN 151.A O no hydrogen 3.176 N/A TYR 165.A OH ASP 146.A OD1 no hydrogen 3.393 N/A TYR 165.A OH ASP 146.A OD2 no hydrogen 2.443 N/A ARG 166.A N LEU 173.A O no hydrogen 2.924 N/A GLY 171.A N GLY 168.A O no hydrogen 3.072 N/A LEU 173.A N ARG 166.A O no hydrogen 2.776 N/A ARG 176.A NH1 PRO 211.A O no hydrogen 3.093 N/A ARG 176.A NH1 TYR 212.A O no hydrogen 3.087 N/A ARG 176.A NH1 LEU 215.A O no hydrogen 3.101 N/A ARG 176.A NH2 LEU 215.A O no hydrogen 3.083 N/A ARG 176.A NH2 ASN 217.A OD1 no hydrogen 2.799 N/A TRP 177.A N PRO 174.A O no hydrogen 2.944 N/A TRP 177.A NE1 GLU 203.A OE1 no hydrogen 2.853 N/A MET 178.A N VAL 175.A O no hydrogen 3.255 N/A GLU 181.A N GLU 181.A OE1 no hydrogen 2.762 N/A SER 182.A N ALA 179.A O no hydrogen 3.097 N/A SER 182.A OG VAL 187.A O no hydrogen 2.706 N/A LEU 183.A N ALA 179.A O no hydrogen 3.142 N/A ASP 185.A N GLU 181.A O no hydrogen 3.428 N/A GLY 186.A N SER 182.A O no hydrogen 2.833 N/A VAL 187.A N ASP 185.A OD2 no hydrogen 2.765 N/A THR 189.A N SER 192.A OG no hydrogen 2.942 N/A THR 190.A OG1 ASN 138.A OD1 no hydrogen 3.210 N/A SER 192.A N THR 189.A OG1 no hydrogen 3.080 N/A SER 192.A OG THR 189.A O no hydrogen 3.063 N/A ASP 193.A N THR 189.A O no hydrogen 2.935 N/A MET 194.A N THR 190.A O no hydrogen 2.928 N/A TRP 195.A N SER 191.A O no hydrogen 3.177 N/A SER 196.A N SER 192.A O no hydrogen 3.185 N/A SER 196.A OG TRP 177.A O no hydrogen 2.651 N/A SER 196.A OG SER 192.A O no hydrogen 3.243 N/A PHE 197.A N ASP 193.A O no hydrogen 2.886 N/A GLY 198.A N MET 194.A O no hydrogen 3.086 N/A VAL 199.A N TRP 195.A O no hydrogen 3.178 N/A VAL 200.A N SER 196.A O no hydrogen 2.885 N/A LEU 201.A N PHE 197.A O no hydrogen 2.989 N/A TRP 202.A N GLY 198.A O no hydrogen 2.998 N/A TRP 202.A NE1 ASP 231.A O no hydrogen 2.906 N/A GLU 203.A N VAL 199.A O no hydrogen 2.805 N/A ILE 204.A N VAL 200.A O no hydrogen 2.760 N/A THR 205.A N LEU 201.A O no hydrogen 2.837 N/A THR 205.A OG1 LEU 201.A O no hydrogen 2.914 N/A THR 205.A OG1 TRP 202.A O no hydrogen 3.382 N/A SER 206.A N GLU 203.A O no hydrogen 3.249 N/A SER 206.A OG TRP 202.A O no hydrogen 2.778 N/A SER 206.A OG GLU 203.A O no hydrogen 3.451 N/A ALA 208.A N GLU 203.A O no hydrogen 2.649 N/A GLU 209.A N SER 206.A OG no hydrogen 3.249 N/A LEU 215.A N TYR 212.A O no hydrogen 3.016 N/A SER 216.A N GLN 219.A OE1 no hydrogen 2.788 N/A SER 216.A OG GLN 219.A OE1 no hydrogen 2.886 N/A GLN 219.A N SER 216.A OG no hydrogen 3.100 N/A VAL 220.A N SER 216.A O no hydrogen 2.883 N/A LEU 221.A N ASN 217.A O no hydrogen 3.105 N/A LYS 222.A N GLU 218.A O no hydrogen 3.359 N/A LYS 222.A NZ ASP 226.A OD2 no hydrogen 2.770 N/A PHE 223.A N GLN 219.A O no hydrogen 2.652 N/A VAL 224.A N VAL 220.A O no hydrogen 2.888 N/A MET 225.A N LEU 221.A O no hydrogen 3.358 N/A ASP 226.A N LYS 222.A O no hydrogen 3.034 N/A GLY 227.A N VAL 224.A O no hydrogen 2.923 N/A GLY 228.A N PHE 223.A O no hydrogen 2.759 N/A CYS 236.A N PRO 233.A O no hydrogen 3.150 N/A CYS 236.A SG GLN 232.A OE1 no hydrogen 3.762 N/A CYS 236.A SG PRO 237.A O no hydrogen 3.716 N/A CYS 236.A SG THR 241.A OG1 no hydrogen 3.395 N/A ARG 239.A NH2 LEU 264.A O no hydrogen 3.369 N/A VAL 240.A N PRO 237.A O no hydrogen 2.939 N/A THR 241.A N PRO 237.A O no hydrogen 2.996 N/A THR 241.A OG1 GLN 232.A OE1 no hydrogen 2.611 N/A THR 241.A OG1 PRO 237.A O no hydrogen 3.526 N/A ASP 242.A N GLU 238.A O no hydrogen 2.914 N/A LEU 243.A N ARG 239.A O no hydrogen 3.407 N/A MET 244.A N VAL 240.A O no hydrogen 3.005 N/A ARG 245.A N THR 241.A O no hydrogen 3.039 N/A MET 246.A N ASP 242.A O no hydrogen 3.148 N/A CYS 247.A N LEU 243.A O no hydrogen 2.952 N/A CYS 247.A SG MET 194.A O no hydrogen 3.598 N/A CYS 247.A SG LEU 243.A O no hydrogen 3.284 N/A TRP 248.A N MET 244.A O no hydrogen 2.929 N/A GLN 249.A NE2 ARG 245.A O no hydrogen 3.312 N/A LYS 253.A N ASN 251.A OD1 no hydrogen 2.972 N/A MET 254.A N ASN 251.A O no hydrogen 3.012 N/A ARG 255.A N PRO 252.A O no hydrogen 3.213 N/A ARG 255.A NE GLN 249.A O no hydrogen 2.826 N/A ARG 255.A NH1 GLU 181.A OE2 no hydrogen 2.866 N/A ARG 255.A NH1 SER 191.A O no hydrogen 3.061 N/A ARG 255.A NH2 GLU 181.A OE1 no hydrogen 2.887 N/A ARG 255.A NH2 GLU 181.A OE2 no hydrogen 3.457 N/A ARG 255.A NH2 GLN 249.A O no hydrogen 3.140 N/A ARG 255.A NH2 PHE 250.A O no hydrogen 3.060 N/A THR 257.A N GLU 260.A OE2 no hydrogen 3.097 N/A GLU 260.A N THR 257.A OG1 no hydrogen 3.096 N/A ILE 261.A N THR 257.A O no hydrogen 2.938 N/A VAL 262.A N PHE 258.A O no hydrogen 3.129 N/A ASN 263.A N LEU 259.A O no hydrogen 2.982 N/A LEU 264.A N GLU 260.A O no hydrogen 3.053 N/A LEU 265.A N ILE 261.A O no hydrogen 3.163 N/A LEU 265.A N VAL 262.A O no hydrogen 3.115 N/A LYS 266.A N ASN 263.A O no hydrogen 3.466 N/A LYS 266.A NZ ASN 263.A O no hydrogen 3.320 N/A LYS 266.A NZ ASN 263.A OD1 no hydrogen 2.716 N/A ASP 268.A N LEU 265.A O no hydrogen 3.135 N/A HIS 270.A N GLN 125.A OE1 no hydrogen 2.977 N/A HIS 270.A ND1 SER 272.A OG no hydrogen 2.843 N/A SER 272.A N HIS 270.A ND1 no hydrogen 3.064 N/A SER 272.A OG HIS 270.A ND1 no hydrogen 2.843 N/A PHE 273.A N HIS 270.A O no hydrogen 2.958 N/A GLU 275.A N SER 272.A O no hydrogen 2.867 N/A VAL 276.A N PHE 273.A O no hydrogen 3.151 N/A SER 277.A N PHE 273.A O no hydrogen 2.865 N/A SER 277.A OG HIS 280.A ND1 no hydrogen 2.794 N/A PHE 278.A N ASP 132.A OD1 no hydrogen 2.736 N/A PHE 279.A N ASP 132.A OD2 no hydrogen 2.788 N/A HIS 280.A N SER 277.A OG no hydrogen 2.891 N/A HIS 280.A ND1 SER 277.A OG no hydrogen 2.794 N/A SER 281.A N PHE 278.A O no hydrogen 2.920 N/A SER 281.A OG PHE 278.A O no hydrogen 2.643 N/A ASN 284.A N SER 281.A O no hydrogen 3.003 N/A ASN 284.A ND2 PHE 279.A O no hydrogen 2.775 N/A LYS 285.A N GLU 282.A O no hydrogen 3.410 N/A