Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8e1x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TRP 7.A N ASP 4.A O no hydrogen 3.121 N/A PHE 9.A N ALA 86.A O no hydrogen 2.932 N/A ARG 11.A NH1 PRO 92.A O no hydrogen 3.030 N/A ARG 11.A NH2 PRO 92.A O no hydrogen 2.900 N/A LYS 13.A N PRO 10.A O no hydrogen 3.219 N/A LEU 14.A N ARG 11.A O no hydrogen 3.182 N/A THR 15.A N GLU 32.A O no hydrogen 2.841 N/A LEU 20.A N VAL 28.A O no hydrogen 3.044 N/A GLY 21.A N VAL 28.A O no hydrogen 3.348 N/A GLY 23.A N GLY 26.A O no hydrogen 2.779 N/A GLY 26.A N GLY 23.A O no hydrogen 3.306 N/A GLN 27.A N MET 51.A O no hydrogen 2.988 N/A VAL 28.A N GLY 21.A O no hydrogen 2.868 N/A VAL 29.A N VAL 49.A O no hydrogen 2.902 N/A MET 30.A N LYS 18.A O no hydrogen 3.139 N/A ALA 31.A N VAL 47.A O no hydrogen 2.741 N/A GLU 32.A N THR 15.A O no hydrogen 2.887 N/A ALA 33.A N VAL 45.A O no hydrogen 2.961 N/A VAL 34.A N LYS 13.A O no hydrogen 2.844 N/A GLY 35.A N GLU 43.A O no hydrogen 3.222 N/A ASP 39.A N ASP 37.A OD1 no hydrogen 3.151 N/A LYS 40.A N ASP 37.A O no hydrogen 3.056 N/A GLU 43.A N LYS 40.A O no hydrogen 3.344 N/A VAL 45.A N ALA 33.A O no hydrogen 2.955 N/A THR 46.A OG1 GLU 32.A OE1 no hydrogen 3.153 N/A VAL 47.A N ALA 31.A O no hydrogen 2.753 N/A ALA 48.A N VAL 96.A O no hydrogen 3.187 N/A VAL 49.A N VAL 29.A O no hydrogen 2.828 N/A LYS 50.A N VAL 94.A O no hydrogen 2.680 N/A LYS 50.A NZ GLU 67.A OE1 no hydrogen 2.645 N/A LYS 50.A NZ GLU 67.A OE2 no hydrogen 3.325 N/A LYS 50.A NZ ASP 175.A OD1 no hydrogen 3.041 N/A MET 51.A N GLN 27.A O no hydrogen 3.084 N/A ALA 56.A N LYS 53.A O no hydrogen 3.289 N/A LEU 61.A N THR 57.A O no hydrogen 3.144 N/A SER 62.A N GLU 58.A O no hydrogen 2.805 N/A SER 62.A OG GLU 58.A O no hydrogen 2.823 N/A SER 62.A OG LYS 59.A O no hydrogen 3.086 N/A ASP 63.A N LYS 59.A O no hydrogen 3.111 N/A LEU 64.A N ASP 60.A O no hydrogen 3.187 N/A LEU 64.A N LEU 61.A O no hydrogen 3.121 N/A VAL 65.A N LEU 61.A O no hydrogen 3.073 N/A SER 66.A N SER 62.A O no hydrogen 2.772 N/A MET 68.A N LEU 64.A O no hydrogen 3.104 N/A GLU 69.A N VAL 65.A O no hydrogen 2.854 N/A MET 71.A N GLU 67.A O no hydrogen 2.945 N/A LYS 72.A N MET 68.A O no hydrogen 3.388 N/A LYS 72.A NZ ASP 4.A OD2 no hydrogen 3.031 N/A LYS 72.A NZ GLU 69.A OE2 no hydrogen 3.283 N/A MET 73.A N MET 70.A O no hydrogen 3.090 N/A HIS 77.A N ASN 82.A OD1 no hydrogen 3.382 N/A ASN 79.A N HIS 77.A ND1 no hydrogen 3.087 N/A ASN 79.A ND2 MET 171.A O no hydrogen 2.982 N/A ILE 81.A N ILE 173.A O no hydrogen 2.922 N/A ASN 82.A N GLU 97.A OE1 no hydrogen 3.134 N/A ASN 82.A ND2 HIS 77.A O no hydrogen 2.972 N/A LEU 84.A N ILE 95.A O no hydrogen 2.737 N/A GLY 85.A N ILE 95.A O no hydrogen 3.201 N/A ALA 86.A N TRP 7.A O no hydrogen 3.125 N/A CYS 87.A SG PHE 9.A O no hydrogen 3.334 N/A THR 88.A N GLU 8.A OE2 no hydrogen 3.019 N/A THR 88.A OG1 GLU 8.A OE1 no hydrogen 2.625 N/A THR 88.A OG1 GLU 8.A OE2 no hydrogen 2.701 N/A ILE 95.A N GLY 85.A O no hydrogen 2.770 N/A VAL 96.A N ALA 48.A O no hydrogen 2.825 N/A GLU 97.A N ASN 82.A O no hydrogen 3.003 N/A LYS 101.A N VAL 165.A O no hydrogen 2.954 N/A GLY 102.A N ALA 99.A O no hydrogen 3.333 N/A ASN 103.A ND2 GLU 106.A OE2 no hydrogen 2.246 N/A LEU 104.A N VAL 163.A O no hydrogen 2.763 N/A ARG 105.A NH1 GLU 106.A OE1 no hydrogen 2.324 N/A ARG 105.A NH1 ASN 188.A O no hydrogen 3.464 N/A ARG 105.A NH2 ASN 188.A O no hydrogen 3.350 N/A GLU 106.A N ASN 103.A OD1 no hydrogen 3.173 N/A TYR 107.A N ASN 103.A O no hydrogen 3.195 N/A LEU 108.A N LEU 104.A O no hydrogen 2.987 N/A ARG 109.A N ARG 105.A O no hydrogen 3.153 N/A ARG 109.A NE GLY 226.A O no hydrogen 2.702 N/A ARG 109.A NH1 GLY 226.A O no hydrogen 3.057 N/A ALA 110.A N GLU 106.A O no hydrogen 3.055 N/A ARG 111.A N LEU 108.A O no hydrogen 3.082 N/A ARG 111.A NH1 TYR 107.A O no hydrogen 2.709 N/A MET 116.A N PRO 113.A O no hydrogen 3.213 N/A THR 130.A N ASP 133.A OD2 no hydrogen 3.073 N/A ASP 133.A N THR 130.A OG1 no hydrogen 3.136 N/A LEU 134.A N THR 130.A O no hydrogen 3.090 N/A VAL 135.A N PHE 131.A O no hydrogen 3.012 N/A SER 136.A N LYS 132.A O no hydrogen 3.403 N/A SER 136.A OG LYS 132.A O no hydrogen 2.918 N/A SER 136.A OG ASP 133.A O no hydrogen 2.987 N/A CYS 137.A N LEU 134.A O no hydrogen 3.195 N/A CYS 137.A SG ASP 133.A O no hydrogen 2.897 N/A CYS 137.A SG LEU 134.A O no hydrogen 3.758 N/A THR 138.A N LEU 134.A O no hydrogen 3.449 N/A THR 138.A OG1 VAL 135.A O no hydrogen 3.186 N/A TYR 139.A N VAL 135.A O no hydrogen 2.948 N/A GLN 140.A N SER 136.A O no hydrogen 2.908 N/A GLN 140.A NE2 SER 136.A O no hydrogen 3.019 N/A LEU 141.A N CYS 137.A O no hydrogen 3.095 N/A ALA 142.A N THR 138.A O no hydrogen 2.665 N/A ARG 143.A N TYR 139.A O no hydrogen 2.862 N/A GLY 144.A N GLN 140.A O no hydrogen 2.918 N/A MET 145.A N LEU 141.A O no hydrogen 2.657 N/A GLU 146.A N ALA 142.A O no hydrogen 2.795 N/A TYR 147.A N ARG 143.A O no hydrogen 3.157 N/A TYR 147.A OH ILE 74.A O no hydrogen 2.809 N/A LEU 148.A N GLY 144.A O no hydrogen 3.125 N/A ALA 149.A N MET 145.A O no hydrogen 2.954 N/A SER 150.A N GLU 146.A O no hydrogen 3.149 N/A SER 150.A OG TYR 147.A O no hydrogen 3.005 N/A GLN 151.A N TYR 147.A O no hydrogen 3.274 N/A GLN 151.A N LEU 148.A O no hydrogen 3.221 N/A LYS 152.A N ALA 149.A O no hydrogen 3.053 N/A CYS 153.A N LEU 148.A O no hydrogen 3.190 N/A CYS 153.A SG PHE 176.A O no hydrogen 3.658 N/A HIS 155.A N ASP 211.A OD2 no hydrogen 2.651 N/A HIS 155.A NE2 ALA 174.A O no hydrogen 2.965 N/A ARG 156.A N ASP 211.A OD1 no hydrogen 3.094 N/A ASP 157.A N HIS 155.A ND1 no hydrogen 3.173 N/A ALA 160.A N GLU 221.A OE1 no hydrogen 2.847 N/A ALA 160.A N GLU 221.A OE2 no hydrogen 3.363 N/A ARG 161.A NH2 ARG 161.A O no hydrogen 3.177 N/A ASN 162.A N ALA 159.A O no hydrogen 2.954 N/A ASN 162.A ND2 ASP 157.A O no hydrogen 3.033 N/A ASN 162.A ND2 ASP 157.A OD2 no hydrogen 3.324 N/A VAL 163.A N ALA 160.A O no hydrogen 3.136 N/A LEU 164.A N LYS 172.A O no hydrogen 2.873 N/A VAL 165.A N GLY 102.A O no hydrogen 2.789 N/A THR 166.A N VAL 170.A O no hydrogen 3.129 N/A ASN 168.A N THR 166.A OG1 no hydrogen 3.205 N/A ASN 169.A N THR 166.A O no hydrogen 3.095 N/A MET 171.A N GLN 140.A OE1 no hydrogen 3.191 N/A LYS 172.A N LEU 164.A O no hydrogen 2.817 N/A LYS 172.A NZ LYS 78.A O no hydrogen 3.138 N/A LYS 172.A NZ ILE 80.A O no hydrogen 3.188 N/A LYS 172.A NZ GLU 97.A OE1 no hydrogen 2.867 N/A ILE 173.A N ASN 79.A O no hydrogen 2.838 N/A ALA 174.A N ASN 162.A O no hydrogen 3.113 N/A ASN 188.A ND2 GLU 22.A O no hydrogen 2.889 N/A ARG 190.A N THR 187.A O no hydrogen 3.482 N/A ARG 190.A NH1 ASP 157.A OD1 no hydrogen 3.333 N/A ARG 190.A NH2 ASP 157.A OD1 no hydrogen 3.336 N/A LYS 194.A N LEU 191.A O no hydrogen 3.189 N/A LYS 194.A NZ PRO 229.A O no hydrogen 3.541 N/A LYS 194.A NZ TYR 230.A O no hydrogen 3.094 N/A TRP 195.A N PRO 192.A O no hydrogen 3.196 N/A TRP 195.A NE1 GLU 221.A OE1 no hydrogen 3.018 N/A MET 196.A N VAL 193.A O no hydrogen 3.232 N/A GLU 199.A N GLU 199.A OE1 no hydrogen 3.211 N/A ALA 200.A N ALA 197.A O no hydrogen 3.091 N/A LEU 201.A N ALA 197.A O no hydrogen 2.911 N/A PHE 202.A N PRO 198.A O no hydrogen 2.769 N/A ASP 203.A N GLU 199.A O no hydrogen 3.117 N/A VAL 205.A N GLU 199.A O no hydrogen 3.291 N/A GLN 209.A NE2 PRO 270.A O no hydrogen 3.010 N/A GLN 209.A NE2 ARG 273.A O no hydrogen 3.160 N/A GLN 209.A NE2 PRO 274.A O no hydrogen 3.511 N/A SER 210.A N THR 207.A O no hydrogen 2.928 N/A SER 210.A N THR 207.A OG1 no hydrogen 3.239 N/A SER 210.A OG GLU 199.A OE2 no hydrogen 2.255 N/A ASP 211.A N THR 207.A O no hydrogen 3.270 N/A VAL 212.A N HIS 208.A O no hydrogen 3.285 N/A TRP 213.A N GLN 209.A O no hydrogen 3.235 N/A SER 214.A N SER 210.A O no hydrogen 3.244 N/A SER 214.A OG TRP 195.A O no hydrogen 2.416 N/A PHE 215.A N ASP 211.A O no hydrogen 2.787 N/A GLY 216.A N VAL 212.A O no hydrogen 3.263 N/A LEU 218.A N SER 214.A O no hydrogen 3.237 N/A MET 219.A N PHE 215.A O no hydrogen 2.811 N/A TRP 220.A N GLY 216.A O no hydrogen 2.991 N/A TRP 220.A NE1 ASP 249.A O no hydrogen 2.915 N/A GLU 221.A N VAL 217.A O no hydrogen 2.842 N/A ILE 222.A N LEU 218.A O no hydrogen 3.043 N/A PHE 223.A N MET 219.A O no hydrogen 3.121 N/A THR 224.A N TRP 220.A O no hydrogen 3.178 N/A THR 224.A OG1 TRP 220.A O no hydrogen 2.878 N/A THR 224.A OG1 GLU 221.A O no hydrogen 3.199 N/A LEU 225.A N ILE 222.A O no hydrogen 2.928 N/A GLY 226.A N GLU 221.A O no hydrogen 2.744 N/A GLY 227.A N THR 224.A OG1 no hydrogen 2.905 N/A ILE 233.A N TYR 230.A O no hydrogen 3.303 N/A GLU 237.A N PRO 234.A O no hydrogen 2.855 N/A LEU 238.A N VAL 235.A O no hydrogen 3.333 N/A LEU 241.A N GLU 237.A O no hydrogen 2.862 N/A LEU 242.A N LEU 238.A O no hydrogen 2.744 N/A LYS 243.A N PHE 239.A O no hydrogen 3.297 N/A GLU 244.A N LYS 240.A O no hydrogen 3.244 N/A GLY 245.A N LEU 242.A O no hydrogen 3.078 N/A ARG 247.A NE HIS 246.A O no hydrogen 2.831 N/A ARG 247.A NH2 LEU 242.A O no hydrogen 3.353 N/A CYS 254.A SG THR 255.A O no hydrogen 3.576 N/A TYR 259.A N THR 255.A O no hydrogen 3.079 N/A TYR 259.A OH MET 248.A O no hydrogen 2.909 N/A MET 260.A N ASN 256.A O no hydrogen 2.614 N/A MET 261.A N GLU 257.A O no hydrogen 3.033 N/A MET 262.A N LEU 258.A O no hydrogen 2.794 N/A ARG 263.A N TYR 259.A O no hydrogen 3.191 N/A ARG 263.A NH1 TYR 259.A OH no hydrogen 3.049 N/A CYS 265.A SG MET 261.A O no hydrogen 3.524 N/A TRP 266.A N ARG 263.A O no hydrogen 2.724 N/A GLN 272.A N VAL 269.A O no hydrogen 3.002 N/A ARG 273.A N PRO 270.A O no hydrogen 2.982 N/A ARG 273.A NE HIS 267.A O no hydrogen 2.924 N/A ARG 273.A NH1 GLU 199.A OE2 no hydrogen 2.598 N/A ARG 273.A NH1 GLN 209.A O no hydrogen 2.828 N/A ARG 273.A NH2 GLU 199.A OE1 no hydrogen 2.424 N/A ARG 273.A NH2 GLU 199.A OE2 no hydrogen 3.310 N/A ARG 273.A NH2 HIS 267.A O no hydrogen 3.451 N/A ARG 273.A NH2 ALA 268.A O no hydrogen 3.530 N/A GLN 278.A N THR 275.A OG1 no hydrogen 3.331 N/A LEU 279.A N THR 275.A O no hydrogen 3.165 N/A VAL 280.A N PHE 276.A O no hydrogen 3.081 N/A GLU 281.A N LYS 277.A O no hydrogen 3.139 N/A ASP 282.A N GLN 278.A O no hydrogen 2.858 N/A LEU 283.A N LEU 279.A O no hydrogen 2.972 N/A ASP 284.A N VAL 280.A O no hydrogen 3.166 N/A ARG 285.A N GLU 281.A O no hydrogen 3.215 N/A ILE 286.A N ASP 282.A O no hydrogen 2.919 N/A LEU 287.A N LEU 283.A O no hydrogen 3.102 N/A LEU 287.A N ASP 284.A O no hydrogen 3.205 N/A THR 288.A N ARG 285.A O no hydrogen 3.441 N/A THR 288.A OG1 ARG 285.A O no hydrogen 3.546 N/A