Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8e3x_R.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 6.A N CYS 2.A O no hydrogen 2.993 N/A GLU 7.A N ILE 3.A O no hydrogen 2.723 N/A ALA 9.A N LYS 5.A O no hydrogen 3.278 N/A MET 10.A N GLU 7.A O no hydrogen 3.002 N/A CYS 11.A N GLN 8.A O no hydrogen 2.984 N/A GLU 13.A N MET 10.A O no hydrogen 2.943 N/A LYS 14.A N MET 10.A O no hydrogen 2.419 N/A ILE 15.A N CYS 11.A O no hydrogen 3.364 N/A ARG 17.A N GLU 13.A O no hydrogen 3.021 N/A ALA 18.A N LYS 14.A O no hydrogen 3.313 N/A ASN 19.A N ILE 15.A O no hydrogen 2.612 N/A GLU 20.A N GLN 16.A O no hydrogen 2.931 N/A GLU 20.A N ARG 17.A O no hydrogen 2.929 N/A LEU 21.A N ARG 17.A O no hydrogen 2.690 N/A CYS 54.A SG CYS 85.A O no hydrogen 3.559 N/A PHE 58.A N PRO 55.A O no hydrogen 3.354 N/A ASP 64.A N ASN 62.A O no hydrogen 2.870 N/A CYS 69.A SG HIS 45.A O no hydrogen 3.401 N/A THR 70.A N GLY 73.A O no hydrogen 2.966 N/A PHE 78.A N GLU 76.A O no hydrogen 2.886 N/A HIS 80.A N PHE 78.A O no hydrogen 2.650 N/A GLU 89.A N GLU 89.A OE2 no hydrogen 2.945 N/A TYR 94.A N GLN 90.A O no hydrogen 2.878 N/A LEU 95.A N ASP 91.A O no hydrogen 2.934 N/A SER 96.A N TYR 92.A O no hydrogen 2.892 N/A SER 96.A OG TYR 92.A O no hydrogen 3.067 N/A SER 96.A OG TYR 93.A O no hydrogen 2.628 N/A VAL 97.A N TYR 93.A O no hydrogen 2.920 N/A LYS 98.A N TYR 94.A O no hydrogen 2.888 N/A ALA 99.A N LEU 95.A O no hydrogen 2.929 N/A LEU 100.A N SER 96.A O no hydrogen 2.884 N/A TYR 101.A N VAL 97.A O no hydrogen 2.961 N/A TYR 101.A OH ASP 151.A OD1 no hydrogen 3.141 N/A TYR 101.A OH ASP 151.A OD2 no hydrogen 3.111 N/A THR 102.A N LYS 98.A O no hydrogen 2.918 N/A THR 102.A OG1 LYS 98.A O no hydrogen 2.785 N/A VAL 103.A N ALA 99.A O no hydrogen 2.923 N/A GLY 104.A N LEU 100.A O no hydrogen 2.957 N/A TYR 105.A N TYR 101.A O no hydrogen 2.835 N/A SER 106.A N THR 102.A O no hydrogen 2.921 N/A SER 106.A OG THR 102.A O no hydrogen 2.934 N/A THR 107.A N VAL 103.A O no hydrogen 2.940 N/A THR 107.A OG1 VAL 103.A O no hydrogen 3.094 N/A SER 108.A N GLY 104.A O no hydrogen 2.904 N/A SER 108.A OG GLY 104.A O no hydrogen 3.333 N/A SER 108.A OG TYR 105.A O no hydrogen 2.757 N/A LEU 109.A N TYR 105.A O no hydrogen 2.846 N/A VAL 110.A N SER 106.A O no hydrogen 2.958 N/A THR 111.A N THR 107.A O no hydrogen 2.945 N/A THR 111.A OG1 THR 107.A O no hydrogen 2.809 N/A LEU 112.A N SER 108.A O no hydrogen 2.858 N/A THR 113.A N LEU 109.A O no hydrogen 2.884 N/A THR 113.A OG1 LEU 109.A O no hydrogen 2.587 N/A THR 114.A N VAL 110.A O no hydrogen 2.986 N/A THR 114.A OG1 VAL 110.A O no hydrogen 2.993 N/A ALA 115.A N THR 111.A O no hydrogen 2.910 N/A MET 116.A N LEU 112.A O no hydrogen 2.837 N/A VAL 117.A N THR 113.A O no hydrogen 2.949 N/A ILE 118.A N THR 114.A O no hydrogen 2.932 N/A LEU 119.A N ALA 115.A O no hydrogen 2.903 N/A CYS 120.A N MET 116.A O no hydrogen 2.862 N/A CYS 120.A SG MET 116.A O no hydrogen 3.307 N/A ARG 121.A N VAL 117.A O no hydrogen 2.951 N/A PHE 122.A N LEU 119.A O no hydrogen 3.469 N/A HIS 126.A ND1 ARG 123.A O no hydrogen 3.218 N/A ARG 129.A NH1 GLU 350.A OE2 no hydrogen 3.328 N/A ARG 129.A NH2 GLU 350.A OE2 no hydrogen 3.256 N/A ASN 130.A ND2 LEU 125.A O no hydrogen 3.032 N/A PHE 131.A N CYS 127.A O no hydrogen 2.683 N/A ILE 132.A N THR 128.A O no hydrogen 2.759 N/A HIS 133.A N ARG 129.A O no hydrogen 2.879 N/A MET 134.A N ASN 130.A O no hydrogen 2.854 N/A ASN 135.A N PHE 131.A O no hydrogen 3.105 N/A LEU 136.A N ILE 132.A O no hydrogen 3.092 N/A PHE 137.A N HIS 133.A O no hydrogen 2.988 N/A VAL 138.A N MET 134.A O no hydrogen 2.829 N/A SER 139.A N ASN 135.A O no hydrogen 2.868 N/A SER 139.A OG LEU 136.A O no hydrogen 2.390 N/A PHE 140.A N LEU 136.A O no hydrogen 2.974 N/A MET 141.A N PHE 137.A O no hydrogen 2.837 N/A LEU 142.A N VAL 138.A O no hydrogen 2.933 N/A ARG 143.A N SER 139.A O no hydrogen 2.907 N/A ARG 143.A NH1 ASN 184.A OD1 no hydrogen 2.877 N/A ALA 144.A N PHE 140.A O no hydrogen 2.933 N/A ILE 145.A N MET 141.A O no hydrogen 2.931 N/A SER 146.A N LEU 142.A O no hydrogen 2.869 N/A SER 146.A OG LEU 142.A O no hydrogen 3.047 N/A SER 146.A OG ARG 143.A O no hydrogen 2.545 N/A VAL 147.A N ARG 143.A O no hydrogen 2.906 N/A PHE 148.A N ALA 144.A O no hydrogen 2.967 N/A ILE 149.A N ILE 145.A O no hydrogen 2.909 N/A LYS 150.A N SER 146.A O no hydrogen 2.890 N/A ASP 151.A N VAL 147.A O no hydrogen 2.929 N/A TRP 152.A N PHE 148.A O no hydrogen 2.927 N/A ILE 153.A N ILE 149.A O no hydrogen 2.919 N/A LEU 154.A N LYS 150.A O no hydrogen 2.883 N/A TYR 155.A N ASP 151.A O no hydrogen 3.349 N/A ALA 156.A N ASP 151.A O no hydrogen 3.081 N/A GLU 157.A N TRP 152.A O no hydrogen 2.827 N/A GLN 158.A NE2 CYS 163.A O no hydrogen 2.723 N/A ASP 159.A N TYR 155.A O no hydrogen 3.188 N/A ASN 161.A N GLU 157.A O no hydrogen 3.159 N/A HIS 162.A N GLN 158.A O no hydrogen 2.634 N/A CYS 163.A N ASN 161.A OD1 no hydrogen 3.228 N/A CYS 163.A SG ASP 1.A O no hydrogen 3.666 N/A CYS 163.A SG ASN 161.A O no hydrogen 3.734 N/A SER 166.A OG GLY 239.A O no hydrogen 3.498 N/A CYS 170.A SG THR 167.A O no hydrogen 3.097 N/A LYS 171.A NZ ASP 237.A OD1 no hydrogen 3.209 N/A LYS 171.A NZ ASP 237.A OD2 no hydrogen 3.524 N/A ALA 172.A N VAL 168.A O no hydrogen 2.912 N/A VAL 173.A N GLU 169.A O no hydrogen 2.885 N/A MET 174.A N CYS 170.A O no hydrogen 2.904 N/A VAL 175.A N LYS 171.A O no hydrogen 2.913 N/A PHE 176.A N ALA 172.A O no hydrogen 2.902 N/A PHE 177.A N VAL 173.A O no hydrogen 2.867 N/A HIS 178.A N MET 174.A O no hydrogen 2.925 N/A TYR 179.A N VAL 175.A O no hydrogen 2.918 N/A CYS 180.A N PHE 176.A O no hydrogen 2.913 N/A CYS 180.A SG LEU 142.A O no hydrogen 3.220 N/A CYS 180.A SG PHE 176.A O no hydrogen 3.144 N/A VAL 181.A N PHE 177.A O no hydrogen 2.993 N/A VAL 182.A N HIS 178.A O no hydrogen 2.933 N/A SER 183.A N TYR 179.A O no hydrogen 2.868 N/A SER 183.A OG CYS 180.A O no hydrogen 2.761 N/A ASN 184.A N CYS 180.A O no hydrogen 2.940 N/A ASN 184.A ND2 SER 139.A OG no hydrogen 2.923 N/A TYR 185.A N VAL 181.A O no hydrogen 3.010 N/A PHE 186.A N VAL 182.A O no hydrogen 2.902 N/A TRP 187.A N SER 183.A O no hydrogen 2.996 N/A LEU 188.A N ASN 184.A O no hydrogen 3.108 N/A LEU 188.A N TYR 185.A O no hydrogen 3.092 N/A PHE 189.A N TYR 185.A O no hydrogen 3.247 N/A ILE 190.A N PHE 186.A O no hydrogen 2.946 N/A GLU 191.A N TRP 187.A O no hydrogen 3.115 N/A GLY 192.A N LEU 188.A O no hydrogen 3.428 N/A LEU 193.A N PHE 189.A O no hydrogen 2.922 N/A TYR 194.A N ILE 190.A O no hydrogen 2.845 N/A LEU 195.A N GLU 191.A O no hydrogen 3.275 N/A PHE 196.A N GLY 192.A O no hydrogen 2.861 N/A THR 197.A N LEU 193.A O no hydrogen 2.615 N/A THR 197.A OG1 LEU 193.A O no hydrogen 2.661 N/A THR 197.A OG1 TYR 213.A OH no hydrogen 2.912 N/A LEU 198.A N TYR 194.A O no hydrogen 2.717 N/A LEU 199.A N LEU 195.A O no hydrogen 2.573 N/A VAL 200.A N PHE 196.A O no hydrogen 2.707 N/A GLU 201.A N THR 197.A O no hydrogen 2.837 N/A TYR 209.A OH GLU 201.A OE1 no hydrogen 3.096 N/A PHE 210.A N ARG 207.A O no hydrogen 3.213 N/A TYR 211.A N ARG 207.A O no hydrogen 3.482 N/A TRP 212.A N ARG 208.A O no hydrogen 3.032 N/A TYR 213.A N TYR 209.A O no hydrogen 2.874 N/A TYR 213.A OH THR 197.A OG1 no hydrogen 2.912 N/A THR 214.A N PHE 210.A O no hydrogen 2.915 N/A THR 214.A OG1 PHE 210.A O no hydrogen 2.817 N/A ILE 215.A N TYR 211.A O no hydrogen 2.942 N/A ILE 216.A N TRP 212.A O no hydrogen 2.896 N/A GLY 217.A N TYR 213.A O no hydrogen 2.896 N/A TRP 218.A N THR 214.A O no hydrogen 2.975 N/A GLY 219.A N ILE 216.A O no hydrogen 3.176 N/A THR 220.A N ILE 216.A O no hydrogen 2.941 N/A THR 220.A OG1 ILE 216.A O no hydrogen 2.814 N/A THR 222.A OG1 TRP 218.A O no hydrogen 3.225 N/A VAL 223.A N GLY 219.A O no hydrogen 2.963 N/A CYS 224.A N THR 220.A O no hydrogen 2.926 N/A CYS 224.A SG THR 220.A O no hydrogen 3.238 N/A VAL 225.A N PRO 221.A O no hydrogen 2.902 N/A THR 226.A N THR 222.A O no hydrogen 2.915 N/A THR 226.A OG1 THR 222.A O no hydrogen 2.701 N/A THR 226.A OG1 VAL 223.A O no hydrogen 2.643 N/A VAL 227.A N VAL 223.A O no hydrogen 2.942 N/A TRP 228.A N CYS 224.A O no hydrogen 2.905 N/A ALA 229.A N VAL 225.A O no hydrogen 2.851 N/A THR 230.A N THR 226.A O no hydrogen 2.930 N/A THR 230.A OG1 THR 226.A O no hydrogen 2.918 N/A THR 230.A OG1 VAL 227.A O no hydrogen 2.603 N/A LEU 231.A N VAL 227.A O no hydrogen 2.917 N/A ARG 232.A N TRP 228.A O no hydrogen 2.888 N/A ARG 232.A NE ASP 236.A O no hydrogen 2.819 N/A ARG 232.A NH2 MET 243.A O no hydrogen 3.230 N/A LEU 233.A N ALA 229.A O no hydrogen 2.895 N/A TYR 234.A N THR 230.A O no hydrogen 2.907 N/A PHE 235.A N LEU 231.A O no hydrogen 2.845 N/A CYS 240.A SG ILE 165.A O no hydrogen 3.545 N/A TRP 241.A N THR 238.A O no hydrogen 3.407 N/A TRP 241.A NE1 ASP 237.A OD1 no hydrogen 2.636 N/A TRP 250.A N SER 246.A O no hydrogen 3.416 N/A TRP 250.A NE1 GLU 318.A OE2 no hydrogen 2.740 N/A TRP 251.A N THR 247.A O no hydrogen 2.899 N/A VAL 252.A N ALA 248.A O no hydrogen 2.918 N/A ILE 253.A N TRP 250.A O no hydrogen 3.225 N/A LYS 254.A N TRP 250.A O no hydrogen 2.916 N/A GLY 255.A N TRP 251.A O no hydrogen 2.883 N/A VAL 258.A N LYS 254.A O no hydrogen 3.148 N/A GLY 259.A N GLY 255.A O no hydrogen 2.906 N/A SER 260.A N PRO 256.A O no hydrogen 2.904 N/A SER 260.A OG VAL 257.A O no hydrogen 2.816 N/A ILE 261.A N VAL 257.A O no hydrogen 2.915 N/A MET 262.A N VAL 258.A O no hydrogen 2.925 N/A VAL 263.A N GLY 259.A O no hydrogen 2.907 N/A ASN 264.A N SER 260.A O no hydrogen 2.972 N/A ASN 264.A N ILE 261.A O no hydrogen 3.115 N/A ASN 264.A ND2 LEU 188.A O no hydrogen 3.040 N/A PHE 265.A N ILE 261.A O no hydrogen 2.915 N/A VAL 266.A N MET 262.A O no hydrogen 2.954 N/A LEU 267.A N VAL 263.A O no hydrogen 3.101 N/A PHE 268.A N ASN 264.A O no hydrogen 2.919 N/A ILE 269.A N PHE 265.A O no hydrogen 2.925 N/A GLY 270.A N VAL 266.A O no hydrogen 2.950 N/A ILE 271.A N LEU 267.A O no hydrogen 2.840 N/A ILE 272.A N PHE 268.A O no hydrogen 2.905 N/A VAL 273.A N ILE 269.A O no hydrogen 2.912 N/A ILE 274.A N GLY 270.A O no hydrogen 2.942 N/A LEU 275.A N ILE 271.A O no hydrogen 2.883 N/A VAL 276.A N ILE 272.A O no hydrogen 2.899 N/A GLN 277.A N VAL 273.A O no hydrogen 2.932 N/A LYS 278.A N ILE 274.A O no hydrogen 2.925 N/A LEU 279.A N LEU 275.A O no hydrogen 2.887 N/A GLN 280.A N VAL 276.A O no hydrogen 3.213 N/A SER 281.A N LYS 278.A O no hydrogen 3.435 N/A SER 281.A OG LYS 278.A O no hydrogen 3.248 N/A GLY 285.A N SER 281.A OG no hydrogen 2.779 N/A ARG 294.A NH2 ARG 294.A O no hydrogen 2.873 N/A LEU 295.A N ILE 291.A O no hydrogen 2.764 N/A ALA 296.A N TYR 292.A O no hydrogen 2.704 N/A ARG 297.A N LEU 293.A O no hydrogen 3.196 N/A SER 298.A N ARG 294.A O no hydrogen 3.094 N/A THR 299.A N LEU 295.A O no hydrogen 2.894 N/A THR 299.A OG1 LEU 295.A O no hydrogen 3.176 N/A LEU 300.A N ALA 296.A O no hydrogen 3.170 N/A LEU 301.A N SER 298.A O no hydrogen 2.924 N/A LEU 302.A N THR 299.A O no hydrogen 2.925 N/A ILE 303.A N THR 299.A O no hydrogen 3.123 N/A PHE 306.A N ILE 303.A O no hydrogen 3.276 N/A GLY 307.A N ILE 303.A O no hydrogen 2.891 N/A ILE 308.A N ILE 303.A O no hydrogen 3.267 N/A TYR 310.A N GLY 307.A O no hydrogen 3.061 N/A THR 311.A N ILE 308.A O no hydrogen 2.901 N/A THR 311.A OG1 ILE 308.A O no hydrogen 2.548 N/A VAL 312.A N HIS 309.A O no hydrogen 3.453 N/A SER 316.A OG PRO 317.A O no hydrogen 3.170 N/A ARG 325.A N SER 321.A O no hydrogen 2.965 N/A ARG 325.A NE GLU 329.A OE1 no hydrogen 3.362 N/A LEU 326.A N LYS 322.A O no hydrogen 2.894 N/A VAL 327.A N ARG 323.A O no hydrogen 2.927 N/A PHE 328.A N GLU 324.A O no hydrogen 2.906 N/A GLU 329.A N ARG 325.A O no hydrogen 2.888 N/A LEU 330.A N LEU 326.A O no hydrogen 3.207 N/A GLY 331.A N LEU 326.A O no hydrogen 2.946 N/A LEU 332.A N VAL 327.A O no hydrogen 3.005 N/A LEU 332.A N PHE 328.A O no hydrogen 3.334 N/A SER 334.A N LEU 330.A O no hydrogen 3.300 N/A SER 334.A OG LEU 330.A O no hydrogen 2.664 N/A GLN 336.A N GLY 333.A O no hydrogen 2.906 N/A GLN 336.A NE2 PRO 304.A O no hydrogen 2.611 N/A VAL 339.A N PHE 335.A O no hydrogen 2.779 N/A VAL 340.A N GLN 336.A O no hydrogen 3.089 N/A VAL 342.A N PHE 338.A O no hydrogen 3.041 N/A LEU 343.A N VAL 339.A O no hydrogen 2.883 N/A TYR 344.A N VAL 340.A O no hydrogen 2.612 N/A TYR 344.A OH LEU 301.A O no hydrogen 2.480 N/A CYS 345.A SG ALA 115.A O no hydrogen 3.861 N/A PHE 346.A N ALA 341.A O no hydrogen 3.196 N/A LEU 347.A N VAL 342.A O no hydrogen 2.954 N/A GLU 350.A N GLU 350.A OE1 no hydrogen 2.705 N/A GLN 352.A N ASN 348.A O no hydrogen 2.971 N/A ALA 353.A N GLY 349.A O no hydrogen 2.914 N/A GLU 354.A N GLU 350.A O no hydrogen 2.894 N/A ILE 355.A N VAL 351.A O no hydrogen 2.886 N/A LYS 356.A N GLN 352.A O no hydrogen 2.920 N/A ARG 357.A N ALA 353.A O no hydrogen 2.912 N/A LYS 358.A N GLU 354.A O no hydrogen 2.888 N/A TRP 359.A N ILE 355.A O no hydrogen 2.886 N/A ARG 360.A N LYS 356.A O no hydrogen 2.918 N/A SER 361.A N ARG 357.A O no hydrogen 3.016 N/A SER 361.A N LYS 358.A O no hydrogen 3.167 N/A SER 361.A OG ARG 357.A O no hydrogen 3.035 N/A TRP 362.A N TRP 359.A O no hydrogen 3.262 N/A