Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8e6c_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 5.A N SER 3.A OG no hydrogen 3.180 N/A VAL 6.A N GLN 297.A OE1 no hydrogen 2.766 N/A LYS 7.A NZ GLU 288.A OE1 no hydrogen 2.711 N/A HIS 10.A N SER 114.A OG no hydrogen 2.954 N/A SER 12.A OG GLU 16.A OE2 no hydrogen 2.608 N/A GLU 16.A N SER 12.A O no hydrogen 2.877 N/A CYS 18.A N VAL 15.A O no hydrogen 2.843 N/A CYS 18.A SG ASP 14.A O no hydrogen 3.491 N/A MET 19.A N GLU 16.A O no hydrogen 3.294 N/A VAL 20.A N GLY 31.A O no hydrogen 2.944 N/A GLN 21.A N GLN 71.A O no hydrogen 2.640 N/A VAL 22.A N LEU 29.A O no hydrogen 2.812 N/A THR 23.A N SER 69.A O no hydrogen 2.852 N/A THR 23.A OG1 THR 28.A OG1 no hydrogen 2.714 N/A CYS 24.A N MET 27.A O no hydrogen 3.372 N/A CYS 24.A SG SER 67.A O no hydrogen 3.369 N/A THR 28.A OG1 VAL 22.A O no hydrogen 3.444 N/A THR 28.A OG1 THR 23.A OG1 no hydrogen 2.714 N/A LEU 29.A N VAL 22.A O no hydrogen 2.940 N/A ASN 30.A N CYS 146.A O no hydrogen 3.009 N/A ASN 30.A ND2 CYS 118.A O no hydrogen 2.834 N/A ASN 30.A ND2 GLY 144.A O no hydrogen 3.101 N/A ASN 30.A ND2 CYS 146.A O no hydrogen 3.034 N/A GLY 31.A N VAL 20.A O no hydrogen 2.765 N/A LEU 32.A N TRP 39.A O no hydrogen 2.705 N/A TRP 33.A N CYS 18.A O no hydrogen 2.651 N/A LEU 34.A N THR 37.A O no hydrogen 2.997 N/A ASP 35.A N THR 99.A OG1 no hydrogen 3.065 N/A THR 37.A N LEU 34.A O no hydrogen 3.089 N/A VAL 38.A N LEU 90.A O no hydrogen 2.601 N/A TRP 39.A N LEU 32.A O no hydrogen 2.819 N/A CYS 40.A N LEU 88.A O no hydrogen 3.281 N/A CYS 40.A SG PRO 41.A O no hydrogen 3.435 N/A ARG 42.A N THR 86.A O no hydrogen 3.425 N/A ARG 42.A NE ASP 188.A OD2 no hydrogen 2.559 N/A ARG 42.A NH2 ASP 188.A OD1 no hydrogen 2.950 N/A ARG 42.A NH2 ASP 188.A OD2 no hydrogen 3.275 N/A MET 45.A N ARG 42.A O no hydrogen 3.476 N/A CYS 46.A N HIS 43.A O no hydrogen 3.230 N/A CYS 46.A SG.A PRO 47.A O no hydrogen 3.512 N/A GLN 50.A N PRO 47.A O no hydrogen 3.074 N/A TYR 56.A OH ASP 188.A O no hydrogen 2.579 N/A ALA 58.A N ASN 55.A OD1 no hydrogen 3.076 N/A LEU 59.A N ASN 55.A O no hydrogen 3.048 N/A LEU 60.A N TYR 56.A O no hydrogen 2.779 N/A ILE 61.A N ASP 57.A O no hydrogen 3.272 N/A SER 62.A N ALA 58.A O no hydrogen 3.010 N/A SER 62.A OG LEU 59.A O no hydrogen 2.621 N/A MET 63.A N LEU 60.A O no hydrogen 3.116 N/A THR 64.A N SER 67.A OG no hydrogen 3.036 N/A ASN 65.A ND2 VAL 78.A O no hydrogen 3.662 N/A HIS 66.A N THR 64.A OG1 no hydrogen 2.946 N/A SER 67.A N THR 64.A O no hydrogen 3.258 N/A SER 69.A N THR 23.A O no hydrogen 2.769 N/A GLN 71.A N GLN 21.A O no hydrogen 2.808 N/A LYS 72.A N ALA 74.A O no hydrogen 2.546 N/A LYS 72.A NZ ALA 17.A O no hydrogen 2.679 N/A LEU 76.A N VAL 70.A O no hydrogen 2.518 N/A VAL 79.A N THR 91.A O no hydrogen 2.645 N/A GLY 80.A N THR 91.A O no hydrogen 3.121 N/A HIS 81.A ND1 ASN 65.A OD1 no hydrogen 2.792 N/A ALA 82.A N LYS 89.A O no hydrogen 2.860 N/A GLN 84.A N LEU 87.A O no hydrogen 2.912 N/A GLN 84.A NE2 ASP 179.A O no hydrogen 3.304 N/A THR 86.A N GLY 180.A O no hydrogen 2.712 N/A THR 86.A OG1 GLY 180.A O no hydrogen 3.017 N/A LEU 87.A N GLN 84.A O no hydrogen 3.036 N/A LEU 88.A N CYS 40.A O no hydrogen 2.795 N/A LYS 89.A N ALA 82.A O no hydrogen 2.507 N/A LEU 90.A N VAL 38.A O no hydrogen 2.947 N/A THR 91.A N GLY 80.A O no hydrogen 2.531 N/A VAL 92.A N ASN 36.A O no hydrogen 2.880 N/A ASN 96.A N ASP 35.A O no hydrogen 3.119 N/A ASN 96.A ND2 ALA 17.A O no hydrogen 3.212 N/A ASN 96.A ND2 TRP 33.A O no hydrogen 2.928 N/A SER 98.A N ASN 96.A OD1 no hydrogen 3.201 N/A THR 99.A N ASN 96.A O no hydrogen 3.159 N/A THR 99.A OG1 ASN 96.A O no hydrogen 2.806 N/A THR 103.A N ILE 158.A O no hydrogen 3.035 N/A THR 105.A N PHE 160.A O no hydrogen 3.041 N/A VAL 107.A N TYR 183.A OH no hydrogen 3.313 N/A GLY 110.A N MET 131.A O no hydrogen 2.758 N/A ALA 111.A N LYS 108.A O no hydrogen 3.082 N/A PHE 113.A N VAL 129.A O no hydrogen 2.978 N/A SER 114.A N TYR 151.A O no hydrogen 2.848 N/A VAL 115.A N PHE 127.A O no hydrogen 2.656 N/A LEU 116.A N VAL 149.A O no hydrogen 3.025 N/A ALA 117.A N GLY 125.A O no hydrogen 2.716 N/A CYS 118.A N SER 148.A OG no hydrogen 2.844 N/A CYS 118.A SG LEU 116.A O no hydrogen 3.495 N/A TYR 119.A N ARG 122.A O no hydrogen 3.062 N/A ASN 120.A ND2 GLN 21.A OE1 no hydrogen 3.043 N/A GLY 121.A N ASN 30.A OD1 no hydrogen 2.665 N/A ARG 122.A N TYR 119.A O no hydrogen 2.980 N/A THR 124.A N ALA 117.A O no hydrogen 2.754 N/A THR 124.A OG1.A ALA 117.A O no hydrogen 2.726 N/A THR 124.A OG1.B ARG 122.A O no hydrogen 3.270 N/A GLY 125.A N ALA 117.A O no hydrogen 3.291 N/A THR 126.A OG1 VAL 115.A O no hydrogen 2.871 N/A PHE 127.A N VAL 115.A O no hydrogen 3.027 N/A THR 128.A OG1 PHE 113.A O no hydrogen 3.483 N/A VAL 129.A N PHE 113.A O no hydrogen 3.051 N/A MET 131.A N ALA 111.A O no hydrogen 2.965 N/A ARG 132.A N THR 136.A O no hydrogen 2.934 N/A ARG 132.A NE ASP 198.A OD1 no hydrogen 3.168 N/A ARG 132.A NE ASP 198.A OD2 no hydrogen 3.286 N/A ARG 132.A NH1 ASP 287.A OD1 no hydrogen 3.153 N/A ARG 132.A NH1 ASP 287.A OD2 no hydrogen 2.996 N/A ARG 132.A NH2 ASP 198.A OD2 no hydrogen 3.283 N/A ARG 132.A NH2 ASP 287.A OD2 no hydrogen 2.612 N/A ASN 134.A ND2 LEU 196.A O no hydrogen 3.533 N/A TYR 135.A N ARG 132.A O no hydrogen 2.774 N/A THR 136.A N ASN 134.A OD1 no hydrogen 3.346 N/A THR 136.A OG1 ASN 134.A OD1 no hydrogen 2.754 N/A ILE 137.A N HIS 173.A O no hydrogen 2.654 N/A LEU 142.A N TYR 119.A OH no hydrogen 2.968 N/A SER 145.A N LEU 142.A O no hydrogen 3.123 N/A SER 145.A OG LEU 142.A O no hydrogen 2.611 N/A CYS 146.A SG HIS 43.A NE2 no hydrogen 3.607 N/A CYS 146.A SG GLN 165.A O no hydrogen 3.154 N/A GLY 147.A N HIS 164.A O no hydrogen 3.299 N/A SER 148.A N SER 145.A O no hydrogen 3.060 N/A SER 148.A OG LEU 116.A O no hydrogen 3.423 N/A SER 148.A OG SER 145.A O no hydrogen 2.785 N/A GLY 150.A N TYR 162.A O no hydrogen 2.613 N/A TYR 151.A N SER 114.A O no hydrogen 2.750 N/A THR 152.A N ASN 159.A O no hydrogen 2.853 N/A THR 152.A OG1 ASN 159.A O no hydrogen 3.385 N/A THR 152.A OG1 ASN 159.A OD1 no hydrogen 3.201 N/A GLU 154.A N VAL 157.A O no hydrogen 3.056 N/A ILE 158.A N ALA 101.A O no hydrogen 2.947 N/A ASN 159.A N THR 152.A O no hydrogen 2.620 N/A ASN 159.A ND2 THR 103.A OG1 no hydrogen 2.884 N/A PHE 160.A N THR 103.A O no hydrogen 2.935 N/A CYS 161.A N GLY 150.A O no hydrogen 2.799 N/A CYS 161.A SG GLY 150.A O no hydrogen 3.404 N/A CYS 161.A SG ASN 159.A O no hydrogen 4.029 N/A TYR 162.A N GLY 150.A O no hydrogen 3.126 N/A TYR 162.A OH HIS 164.A ND1 no hydrogen 3.016 N/A MET 163.A N SER 176.A O no hydrogen 2.871 N/A HIS 164.A N SER 148.A O no hydrogen 2.905 N/A HIS 164.A ND1 TYR 162.A OH no hydrogen 3.016 N/A GLN 165.A N THR 174.A O no hydrogen 3.328 N/A GLN 165.A NE2 THR 86.A O no hydrogen 2.986 N/A GLN 165.A NE2 SER 176.A OG no hydrogen 3.111 N/A MET 166.A N THR 174.A O no hydrogen 3.247 N/A LEU 168.A N THR 172.A O no hydrogen 2.874 N/A GLY 171.A N LEU 168.A O no hydrogen 3.180 N/A THR 172.A N ASN 170.A OD1 no hydrogen 2.968 N/A THR 172.A OG1 ASN 170.A OD1 no hydrogen 2.474 N/A HIS 173.A N ILE 137.A O no hydrogen 2.776 N/A HIS 173.A NE2 GLU 167.A OE1 no hydrogen 2.927 N/A THR 174.A N MET 166.A O no hydrogen 3.165 N/A THR 174.A OG1 TYR 135.A O no hydrogen 3.196 N/A SER 176.A N MET 163.A O no hydrogen 2.984 N/A SER 176.A OG ALA 177.A O no hydrogen 3.318 N/A ALA 177.A N THR 181.A O no hydrogen 2.944 N/A GLY 180.A N ALA 177.A O no hydrogen 3.103 N/A THR 181.A N ASP 179.A OD1 no hydrogen 3.137 N/A THR 181.A OG1 ASP 179.A OD1 no hydrogen 2.854 N/A THR 181.A OG1 ASP 179.A OD2 no hydrogen 3.330 N/A TYR 183.A N GLY 175.A O no hydrogen 2.894 N/A TYR 183.A OH CYS 161.A O no hydrogen 2.315 N/A MET 187.A N GLN 193.A OE1 no hydrogen 2.902 N/A ASP 188.A N ASP 188.A OD1 no hydrogen 2.467 N/A LYS 189.A N MET 187.A O no hydrogen 2.814 N/A GLN 190.A N LEU 51.A O no hydrogen 2.834 N/A VAL 191.A N LYS 189.A O no hydrogen 2.784 N/A GLN 193.A NE2 MET 187.A O no hydrogen 2.470 N/A GLN 193.A NE2 LYS 189.A O no hydrogen 3.270 N/A THR 197.A OG1 ASP 198.A O no hydrogen 3.378 N/A TYR 200.A N GLN 239.A O no hydrogen 3.020 N/A CYS 201.A N ASP 287.A OD2 no hydrogen 2.972 N/A CYS 201.A SG.A ASP 287.A OD2 no hydrogen 3.628 N/A SER 202.A N THR 241.A OG1 no hydrogen 2.818 N/A SER 202.A OG THR 241.A O no hydrogen 2.257 N/A SER 202.A OG THR 241.A OG1 no hydrogen 3.299 N/A ASN 204.A N CYS 201.A O no hydrogen 3.237 N/A ASN 204.A ND2 GLY 110.A O no hydrogen 2.933 N/A ASN 204.A ND2 ASP 287.A O no hydrogen 2.881 N/A VAL 205.A N CYS 201.A O no hydrogen 2.986 N/A VAL 206.A N SER 202.A O no hydrogen 2.913 N/A ALA 207.A N VAL 203.A O no hydrogen 3.272 N/A TRP 208.A N ASN 204.A O no hydrogen 2.922 N/A LEU 209.A N VAL 205.A O no hydrogen 2.871 N/A TYR 210.A N VAL 206.A O no hydrogen 2.910 N/A TYR 210.A OH VAL 258.A O no hydrogen 2.721 N/A ALA 211.A N ALA 207.A O no hydrogen 2.900 N/A ALA 212.A N TRP 208.A O no hydrogen 3.244 N/A ILE 213.A N LEU 209.A O no hydrogen 3.292 N/A LEU 214.A N TYR 210.A O no hydrogen 2.948 N/A ASN 215.A N ALA 212.A O no hydrogen 2.968 N/A ASN 215.A ND2 SER 3.A O no hydrogen 2.867 N/A ASN 215.A ND2 ALA 211.A O no hydrogen 2.942 N/A GLY 216.A N ILE 213.A O no hydrogen 3.112 N/A CYS 217.A N ALA 212.A O no hydrogen 2.647 N/A CYS 217.A SG GLN 278.A O no hydrogen 4.035 N/A TRP 219.A NE1 GLN 278.A O no hydrogen 3.194 N/A VAL 221.A N ALA 218.A O no hydrogen 3.266 N/A THR 226.A N GLU 261.A O no hydrogen 2.860 N/A THR 226.A OG1 GLN 268.A OE1 no hydrogen 2.848 N/A SER 227.A OG SER 230.A OG no hydrogen 2.714 N/A SER 230.A N SER 227.A OG no hydrogen 3.174 N/A SER 230.A OG SER 227.A OG no hydrogen 2.714 N/A PHE 231.A N SER 227.A O no hydrogen 2.799 N/A ASN 232.A N VAL 228.A O no hydrogen 2.805 N/A ASN 232.A ND2 PHE 243.A O no hydrogen 3.405 N/A GLU 233.A N VAL 229.A O no hydrogen 3.128 N/A TRP 234.A N SER 230.A O no hydrogen 2.984 N/A ALA 235.A N PHE 231.A O no hydrogen 2.568 N/A LEU 236.A N ASN 232.A O no hydrogen 3.082 N/A ALA 237.A N TRP 234.A O no hydrogen 3.218 N/A ASN 238.A N ALA 235.A O no hydrogen 3.199 N/A ASN 238.A ND2 TRP 234.A O no hydrogen 2.968 N/A PHE 240.A N ALA 235.A O no hydrogen 3.138 N/A THR 241.A N TYR 200.A O no hydrogen 2.819 N/A THR 241.A OG1 TYR 200.A O no hydrogen 3.009 N/A THR 241.A OG1 SER 202.A OG no hydrogen 3.299 N/A PHE 243.A N ASN 232.A OD1 no hydrogen 2.707 N/A SER 248.A OG.A ASN 295.A OD1 no hydrogen 2.457 N/A VAL 249.A N THR 246.A OG1 no hydrogen 3.350 N/A ASP 250.A N THR 246.A O no hydrogen 3.022 N/A MET 251.A N GLN 247.A O no hydrogen 2.924 N/A LEU 252.A N SER 248.A O no hydrogen 3.278 N/A ALA 253.A N VAL 249.A O no hydrogen 2.989 N/A VAL 254.A N ASP 250.A O no hydrogen 2.867 N/A LYS 255.A N MET 251.A O no hydrogen 2.930 N/A THR 256.A N LEU 252.A O no hydrogen 3.010 N/A THR 256.A OG1 LEU 252.A O no hydrogen 2.764 N/A THR 256.A OG1 ALA 253.A O no hydrogen 3.377 N/A GLY 257.A N ALA 253.A O no hydrogen 2.839 N/A VAL 258.A N THR 256.A OG1 no hydrogen 3.248 N/A ALA 259.A N GLN 262.A OE1 no hydrogen 3.098 N/A GLU 261.A N GLU 261.A OE2 no hydrogen 2.441 N/A GLN 262.A NE2 LYS 222.A O no hydrogen 3.055 N/A LEU 263.A N ALA 259.A O no hydrogen 3.429 N/A LEU 264.A N ILE 260.A O no hydrogen 2.852 N/A TYR 265.A N GLU 261.A O no hydrogen 3.168 N/A ALA 266.A N GLN 262.A O no hydrogen 3.094 N/A ILE 267.A N LEU 263.A O no hydrogen 2.764 N/A GLN 268.A N LEU 264.A O no hydrogen 3.223 N/A GLN 269.A N TYR 265.A O no hydrogen 3.184 N/A LEU 270.A N ALA 266.A O no hydrogen 2.595 N/A TYR 271.A N ILE 267.A O no hydrogen 2.713 N/A THR 272.A OG1 GLN 269.A O no hydrogen 2.389 N/A GLY 273.A N LEU 270.A O no hydrogen 3.100 N/A GLN 275.A NE2 GLY 273.A O no hydrogen 3.229 N/A LYS 277.A N PHE 274.A O no hydrogen 3.247 N/A ILE 279.A N SER 282.A O no hydrogen 2.905 N/A SER 282.A N ILE 279.A O no hydrogen 3.008 N/A SER 282.A OG MET 284.A O no hydrogen 3.161 N/A MET 284.A N SER 282.A OG no hydrogen 3.347 N/A THR 290.A N ASP 293.A OD2 no hydrogen 3.237 N/A THR 290.A OG1 GLU 292.A OE1 no hydrogen 3.271 N/A GLU 292.A N GLU 292.A OE1 no hydrogen 2.530 N/A ASP 293.A N THR 290.A OG1 no hydrogen 3.070 N/A VAL 294.A N THR 290.A O no hydrogen 3.184 N/A ASN 295.A N PRO 291.A O no hydrogen 2.869 N/A MET 296.A N GLU 292.A O no hydrogen 2.838 N/A GLN 297.A N ASP 293.A O no hydrogen 2.784 N/A GLN 297.A NE2 VAL 6.A O no hydrogen 2.754 N/A ILE 298.A N VAL 294.A O no hydrogen 3.337 N/A GLY 300.A N MET 296.A O no hydrogen 3.004 N/A VAL 301.A N ASN 295.A O no hydrogen 2.844 N/A