Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8e6e_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 5.A N SER 3.A OG no hydrogen 3.039 N/A VAL 6.A N GLN 301.A OE1 no hydrogen 2.905 N/A LYS 7.A NZ GLU 292.A OE1 no hydrogen 2.766 N/A HIS 10.A N SER 118.A OG no hydrogen 2.877 N/A SER 12.A OG GLU 16.A OE2 no hydrogen 2.618 N/A VAL 15.A N SER 12.A O no hydrogen 3.049 N/A GLU 16.A N SER 12.A O no hydrogen 2.853 N/A ALA 17.A N GLY 13.A O no hydrogen 3.306 N/A CYS 18.A N VAL 15.A O no hydrogen 2.877 N/A CYS 18.A SG ASP 14.A O no hydrogen 3.556 N/A MET 19.A N GLU 16.A O no hydrogen 3.218 N/A VAL 20.A N GLY 31.A O no hydrogen 2.995 N/A GLN 21.A N GLN 71.A O no hydrogen 2.783 N/A GLN 21.A NE2 THR 28.A OG1 no hydrogen 2.860 N/A VAL 22.A N LEU 29.A O no hydrogen 2.917 N/A THR 23.A N SER 69.A O no hydrogen 2.777 N/A THR 23.A OG1 THR 28.A OG1 no hydrogen 3.214 N/A CYS 24.A N MET 27.A O no hydrogen 2.922 N/A CYS 24.A SG SER 67.A O no hydrogen 3.670 N/A MET 27.A N CYS 24.A O no hydrogen 2.934 N/A THR 28.A OG1 VAL 22.A O no hydrogen 3.440 N/A THR 28.A OG1 THR 23.A OG1 no hydrogen 3.214 N/A LEU 29.A N VAL 22.A O no hydrogen 2.995 N/A ASN 30.A N CYS 150.A O no hydrogen 2.971 N/A ASN 30.A ND2 CYS 122.A O no hydrogen 2.946 N/A ASN 30.A ND2 GLY 148.A O no hydrogen 3.135 N/A ASN 30.A ND2 CYS 150.A O no hydrogen 2.895 N/A GLY 31.A N VAL 20.A O no hydrogen 2.862 N/A LEU 32.A N TRP 39.A O no hydrogen 2.845 N/A TRP 33.A N CYS 18.A O no hydrogen 2.688 N/A TRP 33.A NE1 VAL 98.A O no hydrogen 3.135 N/A LEU 34.A N THR 37.A O no hydrogen 2.868 N/A ASP 35.A N THR 103.A OG1 no hydrogen 2.909 N/A ASN 36.A ND2 VAL 96.A O no hydrogen 2.980 N/A THR 37.A N LEU 34.A O no hydrogen 2.871 N/A VAL 38.A N LEU 94.A O no hydrogen 2.702 N/A TRP 39.A N LEU 32.A O no hydrogen 2.943 N/A CYS 40.A N LEU 92.A O no hydrogen 3.176 N/A CYS 40.A SG PRO 41.A O no hydrogen 3.715 N/A ARG 42.A N THR 90.A O no hydrogen 3.014 N/A ARG 42.A NE ASP 192.A OD2 no hydrogen 2.770 N/A ARG 42.A NH2 ASP 192.A OD1 no hydrogen 2.943 N/A HIS 43.A ND1 GLN 169.A OE1 no hydrogen 3.132 N/A VAL 44.A N PRO 41.A O no hydrogen 3.311 N/A MET 45.A N ARG 42.A O no hydrogen 3.060 N/A CYS 46.A N HIS 43.A O no hydrogen 2.983 N/A CYS 46.A SG.A PRO 47.A O no hydrogen 3.416 N/A CYS 46.A SG.B TYR 56.A OH no hydrogen 3.388 N/A GLN 50.A N PRO 47.A O no hydrogen 2.939 N/A SER 52.A OG.A GLN 194.A O no hydrogen 2.831 N/A ASP 53.A N GLN 50.A O no hydrogen 3.065 N/A TYR 56.A OH ASP 192.A O no hydrogen 2.856 N/A ALA 58.A N ASN 55.A OD1 no hydrogen 3.025 N/A LEU 59.A N ASN 55.A O no hydrogen 2.887 N/A LEU 60.A N TYR 56.A O no hydrogen 2.863 N/A ILE 61.A N ASP 57.A O no hydrogen 3.258 N/A SER 62.A N ALA 58.A O no hydrogen 3.000 N/A SER 62.A OG LEU 59.A O no hydrogen 2.652 N/A MET 63.A N LEU 60.A O no hydrogen 3.114 N/A THR 64.A N SER 67.A OG no hydrogen 2.969 N/A SER 67.A N THR 64.A O no hydrogen 2.916 N/A PHE 68.A N ASN 65.A O no hydrogen 3.363 N/A SER 69.A N THR 23.A O no hydrogen 2.864 N/A GLN 71.A N GLN 21.A O no hydrogen 2.926 N/A LYS 72.A N ALA 78.A O no hydrogen 2.776 N/A LYS 72.A NZ ALA 17.A O no hydrogen 2.821 N/A HIS 73.A NE2 GLN 21.A OE1 no hydrogen 2.508 N/A ALA 78.A N LYS 72.A O no hydrogen 3.276 N/A LEU 80.A N VAL 70.A O no hydrogen 2.876 N/A ARG 81.A N ASP 97.A OD1 no hydrogen 3.095 N/A VAL 83.A N THR 95.A O no hydrogen 2.721 N/A GLY 84.A N THR 95.A O no hydrogen 3.306 N/A HIS 85.A ND1 ASN 65.A OD1 no hydrogen 2.883 N/A ALA 86.A N LYS 93.A O no hydrogen 3.016 N/A GLN 88.A N LEU 91.A O no hydrogen 2.813 N/A GLN 88.A NE2 ASP 183.A O no hydrogen 3.102 N/A THR 90.A N GLY 184.A O no hydrogen 2.831 N/A THR 90.A OG1 SER 180.A OG no hydrogen 2.771 N/A THR 90.A OG1 GLY 184.A O no hydrogen 2.817 N/A LEU 91.A N GLN 88.A O no hydrogen 3.023 N/A LEU 92.A N CYS 40.A O no hydrogen 2.771 N/A LYS 93.A N ALA 86.A O no hydrogen 2.774 N/A LEU 94.A N VAL 38.A O no hydrogen 2.759 N/A THR 95.A N GLY 84.A O no hydrogen 2.828 N/A VAL 96.A N ASN 36.A O no hydrogen 2.814 N/A ASP 97.A N ARG 81.A O no hydrogen 3.049 N/A ASN 100.A N ASP 35.A O no hydrogen 2.877 N/A ASN 100.A ND2 ALA 17.A O no hydrogen 3.323 N/A ASN 100.A ND2 TRP 33.A O no hydrogen 2.903 N/A SER 102.A N ASN 100.A OD1 no hydrogen 2.867 N/A THR 103.A N ASN 100.A O no hydrogen 3.220 N/A THR 103.A OG1 ASN 100.A O no hydrogen 2.792 N/A TYR 106.A OH ASP 35.A OD2 no hydrogen 3.114 N/A THR 107.A N ILE 162.A O no hydrogen 2.848 N/A THR 107.A OG1 ASN 163.A OD1 no hydrogen 2.878 N/A THR 109.A N PHE 164.A O no hydrogen 2.986 N/A VAL 111.A N TYR 187.A OH no hydrogen 3.012 N/A GLY 114.A N MET 135.A O no hydrogen 2.677 N/A ALA 115.A N LYS 112.A O no hydrogen 2.961 N/A PHE 117.A N VAL 133.A O no hydrogen 2.873 N/A SER 118.A N TYR 155.A O no hydrogen 2.867 N/A VAL 119.A N PHE 131.A O no hydrogen 2.750 N/A LEU 120.A N VAL 153.A O no hydrogen 2.951 N/A ALA 121.A N GLY 129.A O no hydrogen 2.815 N/A CYS 122.A N SER 152.A OG no hydrogen 2.880 N/A CYS 122.A SG LEU 120.A O no hydrogen 3.636 N/A TYR 123.A N ARG 126.A O no hydrogen 3.031 N/A GLY 125.A N ASN 30.A OD1 no hydrogen 2.707 N/A ARG 126.A N TYR 123.A O no hydrogen 2.891 N/A THR 128.A N ALA 121.A O no hydrogen 2.782 N/A THR 128.A OG1.A ALA 121.A O no hydrogen 3.185 N/A THR 128.A OG1.B ARG 126.A O no hydrogen 3.114 N/A GLY 129.A N ALA 121.A O no hydrogen 3.281 N/A THR 130.A OG1 VAL 119.A O no hydrogen 2.745 N/A PHE 131.A N VAL 119.A O no hydrogen 3.126 N/A THR 132.A OG1 PHE 117.A O no hydrogen 2.967 N/A VAL 133.A N PHE 117.A O no hydrogen 3.023 N/A MET 135.A N ALA 115.A O no hydrogen 2.901 N/A ARG 136.A N THR 140.A O no hydrogen 2.891 N/A ARG 136.A NE ASP 202.A OD1 no hydrogen 3.422 N/A ARG 136.A NE ASP 202.A OD2 no hydrogen 2.927 N/A ARG 136.A NH1 ASP 291.A OD1 no hydrogen 3.046 N/A ARG 136.A NH1 ASP 291.A OD2 no hydrogen 3.532 N/A ARG 136.A NH2 LYS 203.A O no hydrogen 2.861 N/A ARG 136.A NH2 ASP 291.A OD2 no hydrogen 2.822 N/A ASN 138.A ND2 LEU 200.A O no hydrogen 3.056 N/A TYR 139.A N ARG 136.A O no hydrogen 2.864 N/A THR 140.A OG1 ASN 138.A OD1 no hydrogen 2.824 N/A ILE 141.A N HIS 177.A O no hydrogen 2.760 N/A GLY 143.A N HIS 177.A ND1 no hydrogen 3.186 N/A LEU 146.A N TYR 123.A OH no hydrogen 2.912 N/A SER 149.A N LEU 146.A O no hydrogen 3.062 N/A SER 149.A OG LEU 146.A O no hydrogen 2.682 N/A CYS 150.A SG HIS 43.A NE2 no hydrogen 3.718 N/A CYS 150.A SG GLN 169.A O no hydrogen 3.206 N/A GLY 151.A N HIS 168.A O no hydrogen 3.064 N/A SER 152.A N SER 149.A O no hydrogen 3.033 N/A SER 152.A OG SER 149.A O no hydrogen 2.768 N/A GLY 154.A N TYR 166.A O no hydrogen 2.812 N/A TYR 155.A N SER 118.A O no hydrogen 2.799 N/A THR 156.A N ASN 163.A O no hydrogen 2.968 N/A LYS 157.A NZ ASP 14.A OD2 no hydrogen 2.996 N/A GLU 158.A N VAL 161.A O no hydrogen 2.986 N/A VAL 161.A N GLU 158.A O no hydrogen 2.912 N/A ILE 162.A N ALA 105.A O no hydrogen 2.872 N/A ASN 163.A N THR 156.A O no hydrogen 2.848 N/A ASN 163.A ND2 THR 156.A OG1 no hydrogen 3.049 N/A PHE 164.A N THR 107.A O no hydrogen 2.854 N/A CYS 165.A N GLY 154.A O no hydrogen 2.948 N/A TYR 166.A N GLY 154.A O no hydrogen 3.225 N/A TYR 166.A OH HIS 168.A ND1 no hydrogen 2.804 N/A MET 167.A N SER 180.A O no hydrogen 2.843 N/A HIS 168.A N SER 152.A O no hydrogen 2.815 N/A HIS 168.A ND1 TYR 166.A OH no hydrogen 2.804 N/A GLN 169.A N THR 178.A O no hydrogen 3.114 N/A GLN 169.A NE2 THR 90.A O no hydrogen 3.076 N/A GLN 169.A NE2 SER 180.A OG no hydrogen 2.758 N/A MET 170.A N THR 178.A O no hydrogen 3.029 N/A LEU 172.A N THR 176.A O no hydrogen 2.781 N/A GLY 175.A N LEU 172.A O no hydrogen 2.927 N/A THR 176.A N ASN 174.A OD1 no hydrogen 3.123 N/A THR 176.A OG1 ASN 174.A OD1 no hydrogen 2.724 N/A HIS 177.A N ILE 141.A O no hydrogen 2.822 N/A HIS 177.A NE2 GLU 171.A OE1 no hydrogen 3.029 N/A THR 178.A N MET 170.A O no hydrogen 3.025 N/A THR 178.A OG1 TYR 139.A O no hydrogen 2.946 N/A GLY 179.A N THR 178.A OG1 no hydrogen 2.802 N/A SER 180.A N MET 167.A O no hydrogen 2.880 N/A SER 180.A OG THR 90.A OG1 no hydrogen 2.771 N/A ALA 181.A N THR 185.A O no hydrogen 2.833 N/A GLY 184.A N ALA 181.A O no hydrogen 2.835 N/A THR 185.A N ASP 183.A OD1 no hydrogen 2.903 N/A THR 185.A OG1 ASP 183.A OD1 no hydrogen 2.736 N/A TYR 187.A N GLY 179.A O no hydrogen 2.918 N/A TYR 187.A OH CYS 165.A O no hydrogen 2.620 N/A MET 191.A N GLN 197.A OE1 no hydrogen 2.970 N/A GLN 194.A N LEU 51.A O no hydrogen 2.839 N/A VAL 195.A N LYS 193.A O no hydrogen 2.921 N/A GLN 197.A NE2 MET 191.A O no hydrogen 2.863 N/A GLN 197.A NE2 LYS 193.A O no hydrogen 3.314 N/A GLN 197.A NE2 VAL 195.A O no hydrogen 3.476 N/A LYS 203.A N ASP 202.A OD1 no hydrogen 2.785 N/A TYR 204.A N GLN 243.A O no hydrogen 2.985 N/A CYS 205.A N ASP 291.A OD2 no hydrogen 2.794 N/A SER 206.A N THR 245.A OG1 no hydrogen 2.816 N/A SER 206.A OG THR 245.A O no hydrogen 2.568 N/A ASN 208.A ND2 GLY 114.A O no hydrogen 2.948 N/A ASN 208.A ND2 ASP 291.A O no hydrogen 2.982 N/A VAL 209.A N CYS 205.A O no hydrogen 3.028 N/A VAL 210.A N SER 206.A O no hydrogen 2.944 N/A ALA 211.A N VAL 207.A O no hydrogen 3.013 N/A TRP 212.A N ASN 208.A O no hydrogen 2.975 N/A LEU 213.A N VAL 209.A O no hydrogen 2.930 N/A TYR 214.A N VAL 210.A O no hydrogen 2.908 N/A TYR 214.A OH VAL 262.A O no hydrogen 2.741 N/A ALA 215.A N ALA 211.A O no hydrogen 2.855 N/A ALA 216.A N TRP 212.A O no hydrogen 2.906 N/A ILE 217.A N LEU 213.A O no hydrogen 3.085 N/A LEU 218.A N TYR 214.A O no hydrogen 2.827 N/A ASN 219.A N ALA 216.A O no hydrogen 3.008 N/A ASN 219.A ND2 SER 3.A O no hydrogen 2.951 N/A ASN 219.A ND2 ALA 215.A O no hydrogen 2.916 N/A GLY 220.A N ILE 217.A O no hydrogen 2.887 N/A CYS 221.A N ALA 216.A O no hydrogen 2.820 N/A TRP 223.A NE1 GLN 282.A O no hydrogen 3.082 N/A VAL 225.A N ALA 222.A O no hydrogen 2.963 N/A THR 230.A N GLU 265.A O no hydrogen 2.986 N/A THR 230.A OG1 GLN 272.A OE1 no hydrogen 2.553 N/A SER 231.A OG SER 234.A OG no hydrogen 2.281 N/A SER 234.A N SER 231.A OG no hydrogen 2.926 N/A SER 234.A OG SER 231.A OG no hydrogen 2.281 N/A PHE 235.A N SER 231.A O no hydrogen 2.746 N/A ASN 236.A N VAL 232.A O no hydrogen 2.855 N/A ASN 236.A ND2 PHE 247.A O no hydrogen 3.180 N/A GLU 237.A N VAL 233.A O no hydrogen 3.095 N/A TRP 238.A N SER 234.A O no hydrogen 3.042 N/A ALA 239.A N PHE 235.A O no hydrogen 2.661 N/A LEU 240.A N ASN 236.A O no hydrogen 3.319 N/A ALA 241.A N TRP 238.A O no hydrogen 3.054 N/A ASN 242.A N ALA 239.A O no hydrogen 3.030 N/A ASN 242.A ND2 TRP 238.A O no hydrogen 2.886 N/A PHE 244.A N ALA 239.A O no hydrogen 3.169 N/A THR 245.A N TYR 204.A O no hydrogen 2.882 N/A THR 245.A OG1 TYR 204.A O no hydrogen 3.246 N/A PHE 247.A N ASN 236.A OD1 no hydrogen 2.741 N/A SER 252.A OG.B GLU 296.A OE2 no hydrogen 3.279 N/A VAL 253.A N THR 250.A OG1 no hydrogen 3.208 N/A ASP 254.A N THR 250.A O no hydrogen 2.939 N/A MET 255.A N GLN 251.A O no hydrogen 2.905 N/A ALA 257.A N VAL 253.A O no hydrogen 3.025 N/A VAL 258.A N ASP 254.A O no hydrogen 2.968 N/A LYS 259.A N MET 255.A O no hydrogen 2.936 N/A THR 260.A N LEU 256.A O no hydrogen 3.016 N/A THR 260.A OG1 LEU 256.A O no hydrogen 2.885 N/A THR 260.A OG1 ALA 257.A O no hydrogen 3.558 N/A GLY 261.A N ALA 257.A O no hydrogen 2.847 N/A VAL 262.A N THR 260.A OG1 no hydrogen 3.199 N/A ALA 263.A N GLN 266.A OE1 no hydrogen 2.839 N/A GLU 265.A N GLU 265.A OE1 no hydrogen 2.656 N/A GLN 266.A NE2 LYS 226.A O no hydrogen 3.036 N/A LEU 267.A N ALA 263.A O no hydrogen 3.377 N/A LEU 268.A N ILE 264.A O no hydrogen 2.880 N/A TYR 269.A N GLU 265.A O no hydrogen 3.130 N/A ALA 270.A N GLN 266.A O no hydrogen 3.023 N/A ILE 271.A N LEU 267.A O no hydrogen 2.838 N/A GLN 272.A N LEU 268.A O no hydrogen 3.225 N/A GLN 273.A N TYR 269.A O no hydrogen 3.103 N/A LEU 274.A N ALA 270.A O no hydrogen 2.723 N/A TYR 275.A N ILE 271.A O no hydrogen 2.818 N/A THR 276.A N GLN 273.A O no hydrogen 3.085 N/A THR 276.A OG1 GLN 273.A O no hydrogen 2.507 N/A GLY 277.A N LEU 274.A O no hydrogen 2.968 N/A LYS 281.A N PHE 278.A O no hydrogen 2.990 N/A ILE 283.A N SER 286.A O no hydrogen 2.896 N/A SER 286.A N ILE 283.A O no hydrogen 2.963 N/A SER 286.A OG MET 288.A O no hydrogen 2.858 N/A MET 288.A N SER 286.A OG no hydrogen 3.139 N/A GLU 292.A N GLU 290.A OE2 no hydrogen 2.949 N/A THR 294.A N ASP 297.A OD2 no hydrogen 3.022 N/A THR 294.A OG1 GLU 296.A OE1 no hydrogen 3.450 N/A GLU 296.A N GLU 296.A OE1 no hydrogen 2.829 N/A ASP 297.A N THR 294.A OG1 no hydrogen 2.921 N/A VAL 298.A N THR 294.A O no hydrogen 3.143 N/A ASN 299.A N PRO 295.A O no hydrogen 2.955 N/A ASN 299.A ND2 SER 252.A O no hydrogen 2.953 N/A ASN 299.A ND2 PRO 295.A O no hydrogen 2.967 N/A MET 300.A N GLU 296.A O no hydrogen 2.859 N/A GLN 301.A N ASP 297.A O no hydrogen 2.781 N/A GLN 301.A NE2 VAL 6.A O no hydrogen 2.907 N/A ILE 302.A N VAL 298.A O no hydrogen 3.051 N/A MET 303.A N VAL 298.A O no hydrogen 3.419 N/A GLY 304.A N MET 300.A O no hydrogen 3.231 N/A VAL 305.A N ASN 299.A O no hydrogen 2.965 N/A