Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8e6k_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 3.A N ASP 104.A O no hydrogen 3.074 N/A CYS 10.A N MET 336.A O no hydrogen 2.650 N/A SER 13.A N VAL 366.A O no hydrogen 2.991 N/A SER 13.A OG ASN 367.A OD1 no hydrogen 2.888 N/A GLY 14.A N VAL 366.A O no hydrogen 3.270 N/A TRP 15.A N GLN 309.A OE1 no hydrogen 2.929 N/A ALA 16.A N CYS 364.A O no hydrogen 2.906 N/A TYR 18.A N SER 362.A O no hydrogen 2.575 N/A SER 19.A N SER 362.A O no hydrogen 2.983 N/A LYS 20.A NZ PRO 376.A O no hydrogen 2.509 N/A ASP 21.A N SER 360.A O no hydrogen 3.453 N/A GLY 23.A N ASP 21.A OD1 no hydrogen 2.933 N/A ILE 24.A N SER 359.A OG no hydrogen 3.377 N/A ARG 25.A NH1 GLY 378.A O no hydrogen 2.836 N/A ILE 26.A N ASN 22.A O no hydrogen 3.054 N/A GLY 27.A N GLY 23.A O no hydrogen 2.863 N/A SER 28.A N ARG 25.A O no hydrogen 3.389 N/A LYS 29.A N ILE 26.A O no hydrogen 3.325 N/A GLY 30.A N ILE 26.A O no hydrogen 2.989 N/A PHE 33.A N PRO 85.A O no hydrogen 2.931 N/A VAL 34.A N ALA 56.A O no hydrogen 2.871 N/A ILE 35.A N SER 357.A OG no hydrogen 2.733 N/A ARG 36.A N LEU 52.A O no hydrogen 3.130 N/A ARG 36.A NH1 GLU 343.A OE1 no hydrogen 2.697 N/A GLU 37.A N GLU 343.A OE2 no hydrogen 2.876 N/A PHE 39.A N GLU 37.A O no hydrogen 2.773 N/A SER 41.A N ARG 48.A O no hydrogen 2.918 N/A SER 41.A OG ALA 101.A O no hydrogen 3.282 N/A SER 41.A OG GLU 148.A OE2 no hydrogen 2.756 N/A CYS 42.A N GLU 148.A OE2 no hydrogen 2.976 N/A SER 43.A N GLU 46.A O no hydrogen 2.762 N/A SER 43.A OG GLU 46.A O no hydrogen 2.713 N/A LEU 45.A N SER 43.A OG no hydrogen 3.311 N/A GLU 46.A N SER 43.A OG no hydrogen 2.994 N/A CYS 47.A SG TYR 18.A OH no hydrogen 3.137 N/A ARG 48.A N SER 41.A O no hydrogen 2.913 N/A ARG 48.A NH1 GLU 46.A OE2 no hydrogen 3.335 N/A THR 49.A N CYS 79.A O no hydrogen 2.874 N/A PHE 50.A N PHE 39.A O no hydrogen 2.564 N/A PHE 51.A N MET 77.A O no hydrogen 2.896 N/A LEU 52.A N ARG 36.A O no hydrogen 3.009 N/A THR 53.A N THR 75.A O no hydrogen 2.936 N/A THR 53.A OG1 VAL 34.A O no hydrogen 2.762 N/A GLN 54.A NE2 VAL 67.A O no hydrogen 3.442 N/A GLY 55.A N THR 53.A OG1 no hydrogen 3.314 N/A LEU 58.A N VAL 32.A O no hydrogen 3.056 N/A ASN 59.A ND2 GLY 27.A O no hydrogen 3.598 N/A SER 63.A N ASP 60.A O no hydrogen 3.512 N/A SER 63.A OG ASP 60.A O no hydrogen 3.085 N/A GLY 65.A N ILE 354.A O no hydrogen 2.815 N/A ARG 70.A NE ASP 117.A OD1 no hydrogen 3.312 N/A ARG 70.A NE ASP 117.A OD2 no hydrogen 3.166 N/A ARG 70.A NH2 ASP 117.A OD2 no hydrogen 2.533 N/A SER 71.A OG GLN 54.A OE1 no hydrogen 2.713 N/A SER 71.A OG LYS 68.A O no hydrogen 2.410 N/A ARG 74.A N SER 71.A O no hydrogen 3.437 N/A ARG 74.A NH2 ASP 69.A OD1 no hydrogen 3.446 N/A THR 75.A N THR 53.A O no hydrogen 2.842 N/A LEU 76.A N SER 94.A O no hydrogen 2.805 N/A MET 77.A N PHE 51.A O no hydrogen 2.931 N/A SER 78.A N ARG 91.A O no hydrogen 2.770 N/A SER 78.A OG GLU 93.A OE2 no hydrogen 2.755 N/A CYS 79.A N THR 49.A O no hydrogen 2.936 N/A CYS 79.A SG PRO 80.A O no hydrogen 3.498 N/A CYS 79.A SG GLU 83.A O no hydrogen 3.910 N/A VAL 81.A N CYS 47.A O no hydrogen 3.345 N/A GLU 83.A N PRO 80.A O no hydrogen 3.285 N/A SER 86.A N ASN 89.A OD1 no hydrogen 2.827 N/A SER 86.A OG ASP 31.A O no hydrogen 2.474 N/A ASN 89.A ND2 ALA 84.A O no hydrogen 3.124 N/A SER 90.A OG SER 86.A O no hydrogen 2.385 N/A SER 90.A OG ASN 89.A OD1 no hydrogen 3.040 N/A ARG 91.A NE GLU 93.A OE2 no hydrogen 3.334 N/A ARG 91.A NH2 GLU 93.A OE2 no hydrogen 3.042 N/A GLU 93.A N LEU 76.A O no hydrogen 3.024 N/A SER 94.A N LEU 76.A O no hydrogen 2.972 N/A ALA 96.A N ARG 74.A O no hydrogen 3.047 N/A TRP 97.A N ILE 113.A O no hydrogen 2.481 N/A TRP 97.A NE1 GLY 115.A O no hydrogen 2.889 N/A SER 98.A N ILE 113.A O no hydrogen 3.120 N/A SER 98.A OG GLU 146.A OE2 no hydrogen 2.549 N/A ALA 99.A N GLU 146.A OE1 no hydrogen 3.267 N/A SER 100.A N ILE 111.A O no hydrogen 2.852 N/A CYS 102.A N LEU 109.A O no hydrogen 2.946 N/A ASP 104.A N GLY 107.A O no hydrogen 3.474 N/A GLY 105.A N HIS 103.A ND1 no hydrogen 3.114 N/A MET 106.A N ASP 104.A OD1 no hydrogen 2.952 N/A GLY 107.A N ASP 104.A OD1 no hydrogen 2.980 N/A TRP 108.A N ASN 127.A OD1 no hydrogen 3.315 N/A LEU 109.A N CYS 102.A O no hydrogen 2.803 N/A THR 110.A N LYS 125.A O no hydrogen 2.914 N/A THR 110.A OG1 GLU 93.A OE1 no hydrogen 3.330 N/A ILE 111.A N SER 100.A O no hydrogen 2.901 N/A GLY 112.A N VAL 123.A O no hydrogen 2.975 N/A ILE 113.A N SER 98.A O no hydrogen 2.705 N/A SER 114.A N VAL 121.A O no hydrogen 2.988 N/A GLY 115.A N SER 114.A OG no hydrogen 2.837 N/A GLY 119.A N PRO 116.A O no hydrogen 3.180 N/A VAL 121.A N SER 114.A O no hydrogen 2.869 N/A ALA 122.A N ILE 134.A O no hydrogen 2.800 N/A VAL 123.A N GLY 112.A O no hydrogen 2.723 N/A LEU 124.A N ASP 132.A O no hydrogen 2.852 N/A LYS 125.A N THR 110.A O no hydrogen 2.815 N/A LYS 125.A NZ GLU 93.A O no hydrogen 2.611 N/A TYR 126.A N ILE 129.A O no hydrogen 2.676 N/A TYR 126.A OH ASP 104.A OD1 no hydrogen 3.389 N/A TYR 126.A OH ASP 104.A OD2 no hydrogen 3.346 N/A ASN 127.A N TRP 108.A O no hydrogen 2.949 N/A ILE 129.A N TYR 126.A O no hydrogen 3.039 N/A THR 131.A N LEU 124.A O no hydrogen 2.702 N/A ASP 132.A N LEU 124.A O no hydrogen 2.998 N/A THR 133.A N ASP 132.A OD1 no hydrogen 2.495 N/A ILE 134.A N ALA 122.A O no hydrogen 2.904 N/A LYS 135.A NZ GLY 119.A O no hydrogen 3.122 N/A SER 136.A N ALA 120.A O no hydrogen 3.199 N/A TRP 137.A NE1 SER 170.A OG no hydrogen 3.092 N/A ARG 138.A N ASP 162.A OD2 no hydrogen 2.564 N/A ASN 140.A N ASP 162.A OD1 no hydrogen 3.105 N/A ILE 141.A N ASP 117.A O no hydrogen 2.647 N/A ARG 143.A N THR 161.A O no hydrogen 2.723 N/A ARG 143.A NH1 GLY 163.A O no hydrogen 3.231 N/A ARG 143.A NH2 GLY 163.A O no hydrogen 3.113 N/A THR 144.A N SER 98.A OG no hydrogen 3.325 N/A GLN 145.A N THR 144.A OG1 no hydrogen 2.555 N/A GLN 145.A NE2 THR 158.A OG1 no hydrogen 2.956 N/A CYS 149.A N ALA 101.A O no hydrogen 3.382 N/A ALA 150.A N PHE 157.A O no hydrogen 3.034 N/A CYS 151.A SG HIS 103.A O no hydrogen 3.277 N/A VAL 152.A N SER 155.A O no hydrogen 2.845 N/A ASN 153.A N THR 4.A O no hydrogen 2.849 N/A GLY 154.A N LEU 3.A O no hydrogen 3.215 N/A SER 155.A N VAL 152.A O no hydrogen 2.931 N/A SER 155.A OG GLU 177.A OE2 no hydrogen 3.283 N/A CYS 156.A N ILE 176.A O no hydrogen 2.938 N/A PHE 157.A N ALA 150.A O no hydrogen 2.829 N/A THR 158.A N LEU 174.A O no hydrogen 3.042 N/A THR 158.A OG1 ILE 159.A O no hydrogen 3.523 N/A MET 160.A N LYS 172.A O no hydrogen 2.938 N/A THR 161.A N ARG 143.A O no hydrogen 2.719 N/A THR 161.A OG1 TYR 194.A O no hydrogen 2.414 N/A ASP 162.A N SER 170.A O no hydrogen 2.979 N/A GLY 163.A N ASN 140.A O no hydrogen 3.071 N/A GLN 168.A NE2 ALA 189.A O no hydrogen 3.427 N/A ALA 169.A N TYR 171.A OH no hydrogen 3.272 N/A SER 170.A N ASP 162.A O no hydrogen 2.884 N/A SER 170.A OG ASP 162.A O no hydrogen 2.640 N/A LYS 172.A N MET 160.A O no hydrogen 2.935 N/A LYS 172.A NZ SER 184.A OG no hydrogen 3.370 N/A ILE 173.A N ILE 185.A O no hydrogen 2.862 N/A LEU 174.A N THR 158.A O no hydrogen 2.999 N/A LYS 175.A N LYS 183.A O no hydrogen 2.942 N/A LYS 175.A NZ GLN 226.A O no hydrogen 3.182 N/A ILE 176.A N CYS 156.A O no hydrogen 2.790 N/A GLU 177.A N LYS 180.A O no hydrogen 2.750 N/A LYS 178.A NZ GLY 154.A O no hydrogen 3.354 N/A LYS 180.A N GLU 177.A O no hydrogen 3.201 N/A THR 182.A N LYS 175.A O no hydrogen 3.063 N/A THR 182.A OG1 LYS 175.A O no hydrogen 3.471 N/A THR 182.A OG1 GLU 177.A OE1 no hydrogen 3.256 N/A ILE 185.A N ILE 173.A O no hydrogen 3.013 N/A LEU 187.A N TYR 171.A O no hydrogen 2.620 N/A ASN 188.A N TYR 230.A OH no hydrogen 2.876 N/A ASN 191.A N GLN 168.A OE1 no hydrogen 3.067 N/A TYR 192.A N ALA 189.A O no hydrogen 3.297 N/A HIS 193.A NE2 GLU 195.A OE1 no hydrogen 3.252 N/A GLU 195.A N ARG 211.A O no hydrogen 3.218 N/A SER 198.A N VAL 209.A O no hydrogen 2.903 N/A SER 198.A OG SER 323.A OG no hydrogen 2.608 N/A CYS 199.A SG GLN 145.A OE1 no hydrogen 3.062 N/A TYR 200.A N MET 207.A O no hydrogen 2.905 N/A ASP 202.A N LYS 205.A O no hydrogen 2.751 N/A THR 203.A N SER 7.A O no hydrogen 3.214 N/A THR 203.A OG1 THR 203.A O no hydrogen 2.539 N/A GLY 204.A N GLY 5.A O no hydrogen 3.242 N/A LYS 205.A N ASP 202.A O no hydrogen 2.996 N/A VAL 206.A N PHE 224.A O no hydrogen 2.923 N/A MET 207.A N TYR 200.A O no hydrogen 2.972 N/A CYS 208.A N VAL 222.A O no hydrogen 2.921 N/A VAL 209.A N SER 198.A O no hydrogen 2.872 N/A CYS 210.A N PRO 220.A O no hydrogen 3.103 N/A ARG 211.A N GLU 195.A O no hydrogen 2.933 N/A ARG 211.A NE ASN 213.A OD1 no hydrogen 2.628 N/A ARG 211.A NH1 GLU 196.A OE1 no hydrogen 2.681 N/A ARG 211.A NH1 TYR 320.A OH no hydrogen 3.069 N/A ARG 211.A NH2 ASN 262.A O no hydrogen 2.705 N/A TRP 214.A N ASP 212.A OD1 no hydrogen 2.966 N/A HIS 215.A N ASP 212.A OD1 no hydrogen 3.143 N/A GLY 216.A N ASP 212.A OD1 no hydrogen 3.149 N/A SER 217.A OG SER 258.A O no hydrogen 3.182 N/A ASN 218.A ND2 ILE 235.A O no hydrogen 3.227 N/A ARG 219.A NE GLY 241.A O no hydrogen 2.976 N/A ARG 219.A NH1 ILE 264.A O no hydrogen 2.977 N/A ARG 219.A NH2 GLY 241.A O no hydrogen 2.918 N/A ARG 219.A NH2 ILE 264.A O no hydrogen 2.676 N/A TRP 221.A N GLY 233.A O no hydrogen 2.858 N/A VAL 222.A N CYS 208.A O no hydrogen 2.926 N/A SER 223.A N GLN 231.A O no hydrogen 2.942 N/A PHE 224.A N VAL 206.A O no hydrogen 2.893 N/A ASP 225.A N ASP 229.A O no hydrogen 2.983 N/A GLN 226.A NE2 VAL 152.A O no hydrogen 3.159 N/A LEU 228.A N ASP 225.A O no hydrogen 2.900 N/A GLN 231.A N SER 223.A O no hydrogen 2.913 N/A GLY 233.A N TRP 221.A O no hydrogen 2.998 N/A TYR 234.A OH ASP 212.A OD2 no hydrogen 2.167 N/A ILE 235.A N ARG 219.A O no hydrogen 3.309 N/A CYS 236.A SG TRP 298.A O no hydrogen 3.337 N/A CYS 236.A SG THR 299.A O no hydrogen 3.126 N/A SER 237.A N GLY 297.A O no hydrogen 2.910 N/A SER 237.A OG ASP 294.A OD2 no hydrogen 3.196 N/A GLY 238.A N ASP 302.A O no hydrogen 2.776 N/A VAL 239.A N SER 237.A OG no hydrogen 3.073 N/A ASN 243.A N ASP 242.A OD1 no hydrogen 2.740 N/A ASN 243.A ND2 SER 285.A O no hydrogen 3.431 N/A ARG 245.A NE PHE 240.A O no hydrogen 3.194 N/A ARG 245.A NE ASP 242.A O no hydrogen 2.667 N/A ARG 245.A NH1 THR 280.A O no hydrogen 2.480 N/A ARG 245.A NH1 SER 282.A O no hydrogen 2.681 N/A GLY 251.A N THR 301.A O no hydrogen 3.368 N/A SER 252.A OG GLY 254.A O no hydrogen 3.116 N/A CYS 253.A SG THR 299.A O no hydrogen 3.881 N/A ASN 259.A ND2 ARG 245.A O no hydrogen 2.992 N/A GLY 260.A N SER 257.A O no hydrogen 3.262 N/A ALA 261.A N ASN 259.A O no hydrogen 2.949 N/A ILE 264.A N ASP 242.A OD1 no hydrogen 2.629 N/A LYS 265.A NZ GLU 196.A O no hydrogen 3.277 N/A SER 268.A OG PHE 267.A O no hydrogen 2.706 N/A PHE 269.A N TRP 276.A O no hydrogen 2.986 N/A ARG 270.A N TYR 200.A OH no hydrogen 3.012 N/A ARG 270.A NE ASP 272.A O no hydrogen 3.176 N/A TYR 271.A N GLY 274.A O no hydrogen 2.863 N/A TYR 271.A OH CYS 10.A O no hydrogen 3.064 N/A GLY 274.A N TYR 271.A O no hydrogen 2.993 N/A VAL 275.A N ASP 294.A O no hydrogen 2.937 N/A TRP 276.A N PHE 269.A O no hydrogen 2.841 N/A ILE 277.A N ILE 292.A O no hydrogen 2.855 N/A ARG 279.A N GLU 290.A O no hydrogen 2.892 N/A ARG 279.A NE GLU 290.A OE2 no hydrogen 3.166 N/A ARG 279.A NH1 ASP 248.A OD2 no hydrogen 2.760 N/A ARG 279.A NH2 GLU 290.A OE2 no hydrogen 2.550 N/A LYS 281.A NZ ASP 310.A OD1 no hydrogen 2.472 N/A SER 282.A N SER 287.A O no hydrogen 3.195 N/A SER 282.A OG SER 285.A OG no hydrogen 3.149 N/A SER 285.A OG SER 282.A OG no hydrogen 3.149 N/A SER 285.A OG SER 287.A OG no hydrogen 3.368 N/A SER 287.A OG SER 285.A OG no hydrogen 3.368 N/A SER 287.A OG ILE 314.A O no hydrogen 2.976 N/A GLY 288.A N ASP 316.A O no hydrogen 2.967 N/A PHE 289.A N VAL 312.A O no hydrogen 3.032 N/A GLU 290.A N ARG 279.A O no hydrogen 2.876 N/A MET 291.A N GLN 309.A O no hydrogen 3.010 N/A ILE 292.A N ILE 277.A O no hydrogen 2.921 N/A TRP 293.A N VAL 307.A O no hydrogen 2.858 N/A ASP 294.A N VAL 275.A O no hydrogen 2.902 N/A GLY 297.A N ASP 294.A O no hydrogen 3.225 N/A TRP 298.A N ASN 273.A O no hydrogen 2.675 N/A THR 299.A OG1 ASN 273.A OD1 no hydrogen 3.038 N/A GLU 300.A N ASN 296.A O no hydrogen 2.703 N/A SER 304.A N ASP 302.A OD1 no hydrogen 2.936 N/A SER 306.A N TRP 293.A O no hydrogen 2.894 N/A ARG 308.A NH1 GLU 290.A OE1 no hydrogen 3.216 N/A GLN 309.A N MET 291.A O no hydrogen 2.978 N/A GLN 309.A NE2 TRP 15.A O no hydrogen 3.325 N/A GLN 309.A NE2 VAL 371.A O no hydrogen 3.000 N/A VAL 312.A N PHE 289.A O no hydrogen 2.848 N/A ASP 316.A N ALA 313.A O no hydrogen 3.409 N/A SER 318.A N ARG 286.A O no hydrogen 2.712 N/A SER 318.A OG GLY 288.A O no hydrogen 3.237 N/A GLY 319.A N SER 318.A OG no hydrogen 2.680 N/A SER 321.A N LYS 265.A O no hydrogen 3.456 N/A GLY 322.A N TRP 341.A O no hydrogen 2.945 N/A SER 323.A N SER 198.A OG no hydrogen 3.281 N/A SER 323.A OG SER 198.A OG no hydrogen 2.608 N/A PHE 324.A N CYS 339.A O no hydrogen 2.912 N/A VAL 325.A N GLU 148.A OE1 no hydrogen 3.187 N/A GLN 326.A N ARG 337.A O no hydrogen 2.950 N/A THR 331.A N HIS 327A.A O no hydrogen 3.322 N/A GLY 332.A N PRO 328B.A O no hydrogen 3.032 N/A LEU 333.A N THR 331.A OG1 no hydrogen 3.412 N/A MET 336.A N SER 8.A O no hydrogen 3.075 N/A ARG 337.A N GLN 326.A O no hydrogen 2.990 N/A CYS 339.A N PHE 324.A O no hydrogen 2.845 N/A CYS 339.A SG GLN 326.A OE1 no hydrogen 3.220 N/A CYS 339.A SG ARG 337.A O no hydrogen 3.962 N/A PHE 340.A N PHE 363.A O no hydrogen 2.865 N/A TRP 341.A N GLY 322.A O no hydrogen 2.891 N/A VAL 342.A N ILE 361.A O no hydrogen 2.889 N/A GLU 343.A N TYR 320.A O no hydrogen 2.522 N/A LEU 344.A N SER 359.A O no hydrogen 2.816 N/A ILE 345.A N SER 318.A O no hydrogen 2.963 N/A ARG 346.A N SER 357.A O no hydrogen 3.250 N/A ARG 346.A NE GLU 351.A OE1 no hydrogen 2.960 N/A GLN 348.A N TRP 355.A O no hydrogen 3.166 N/A LYS 350.A N GLY 347.A O no hydrogen 3.106 N/A GLU 351.A N GLY 347.A O no hydrogen 3.180 N/A THR 353.A N GLU 351.A O no hydrogen 2.831 N/A THR 356.A OG1 GLN 348.A O no hydrogen 2.989 N/A SER 357.A OG ILE 35.A O no hydrogen 3.437 N/A SER 357.A OG GLY 358.A O no hydrogen 3.410 N/A GLY 358.A N ILE 35.A O no hydrogen 2.974 N/A SER 359.A N LEU 344.A O no hydrogen 2.924 N/A SER 360.A N ASP 21.A OD1 no hydrogen 3.379 N/A SER 360.A N ASP 21.A OD2 no hydrogen 3.288 N/A SER 360.A OG ILE 361.A O no hydrogen 3.467 N/A ILE 361.A N VAL 342.A O no hydrogen 2.980 N/A SER 362.A N SER 19.A O no hydrogen 2.887 N/A SER 362.A OG PHE 340.A O no hydrogen 3.279 N/A PHE 363.A N PHE 340.A O no hydrogen 2.912 N/A CYS 364.A N ALA 16.A O no hydrogen 2.698 N/A CYS 364.A SG GLN 326.A OE1 no hydrogen 3.111 N/A GLY 365.A N PRO 338.A O no hydrogen 2.935 N/A VAL 366.A N GLY 14.A O no hydrogen 2.917 N/A GLY 378.A N ASP 377.A OD1 no hydrogen 2.908 N/A SER 384.A OG ASN 59.A OD1 no hydrogen 3.009 N/A TYR 88A.A OH ASP 31.A OD2 no hydrogen 2.596 N/A GLU 329C.A N GLU 329C.A OE1 no hydrogen 2.941 N/A LEU 330D.A N HIS 327A.A O no hydrogen 2.900 N/A