Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8ec0_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 4.A N THR 14.A O no hydrogen 3.293 N/A GLN 5.A NE2 THR 4.A O no hydrogen 2.412 N/A SER 7.A OG LEU 6.A O no hydrogen 2.641 N/A ASN 8.A N ILE 10.A O no hydrogen 3.171 N/A VAL 12.A N LEU 6.A O no hydrogen 3.336 N/A ALA 13.A N VAL 182.A O no hydrogen 3.285 N/A THR 14.A OG1 ALA 13.A O no hydrogen 2.762 N/A SER 24.A N THR 185.A O no hydrogen 2.882 N/A SER 24.A OG THR 185.A O no hydrogen 3.283 N/A VAL 25.A N VAL 80.A O no hydrogen 3.208 N/A VAL 28.A N VAL 181.A O no hydrogen 3.079 N/A PHE 29.A N GLN 76.A O no hydrogen 2.968 N/A GLY 30.A N ASN 179.A O no hydrogen 2.969 N/A ASN 35.A N GLY 32.A O no hydrogen 3.252 N/A ASN 40.A N ASN 37.A O no hydrogen 2.878 N/A ASN 45.A ND2 THR 152.A O no hydrogen 2.289 N/A LEU 46.A N GLY 42.A O no hydrogen 2.901 N/A TRP 47.A N VAL 43.A O no hydrogen 2.916 N/A LYS 48.A N SER 44.A O no hydrogen 2.901 N/A ASN 49.A N ASN 45.A O no hydrogen 2.919 N/A ILE 50.A N LEU 46.A O no hydrogen 2.879 N/A PHE 51.A N TRP 47.A O no hydrogen 2.955 N/A LEU 52.A N LYS 48.A O no hydrogen 2.919 N/A SER 53.A OG ASN 49.A O no hydrogen 3.086 N/A SER 53.A OG ILE 50.A O no hydrogen 3.182 N/A GLU 55.A N GLU 55.A OE1 no hydrogen 2.596 N/A ASN 56.A ND2 LEU 52.A O no hydrogen 3.522 N/A SER 57.A N LYS 54.A O no hydrogen 3.318 N/A VAL 59.A N GLU 55.A O no hydrogen 2.924 N/A ALA 61.A N SER 57.A O no hydrogen 2.926 N/A LYS 62.A N ALA 58.A O no hydrogen 2.903 N/A GLU 63.A N VAL 59.A O no hydrogen 3.253 N/A SER 68.A N ILE 79.A O no hydrogen 2.983 N/A SER 68.A OG SER 69.A O no hydrogen 3.453 N/A SER 69.A OG SER 68.A O no hydrogen 2.707 N/A ASN 70.A N SER 77.A O no hydrogen 3.262 N/A SER 77.A N ASN 70.A O no hydrogen 3.073 N/A SER 77.A OG ASN 70.A O no hydrogen 3.367 N/A SER 77.A OG ASN 362.A OD1 no hydrogen 3.195 N/A TYR 78.A N VAL 27.A O no hydrogen 3.131 N/A TYR 78.A OH PHE 51.A O no hydrogen 2.965 N/A VAL 80.A N VAL 25.A O no hydrogen 3.213 N/A SER 81.A N ALA 66.A O no hydrogen 3.077 N/A SER 81.A OG ALA 66.A O no hydrogen 3.466 N/A SER 82.A OG LEU 83.A O no hydrogen 3.381 N/A SER 82.A OG SER 86.A O no hydrogen 2.701 N/A SER 86.A N LEU 83.A O no hydrogen 3.153 N/A SER 86.A OG SER 82.A OG no hydrogen 2.600 N/A SER 86.A OG LEU 83.A O no hydrogen 3.312 N/A LYS 89.A N ASP 88.A OD1 no hydrogen 2.756 N/A SER 90.A OG THR 87.A O no hydrogen 2.339 N/A LEU 91.A N THR 87.A O no hydrogen 2.943 N/A ASP 92.A N ASP 88.A O no hydrogen 2.890 N/A PHE 93.A N LYS 89.A O no hydrogen 2.916 N/A LEU 94.A N SER 90.A O no hydrogen 2.917 N/A ASN 95.A N LEU 91.A O no hydrogen 2.930 N/A GLN 96.A N ASP 92.A O no hydrogen 2.911 N/A GLN 96.A NE2 ASP 92.A O no hydrogen 3.377 N/A SER 97.A N PHE 93.A O no hydrogen 2.875 N/A SER 97.A N LEU 94.A O no hydrogen 3.173 N/A PHE 98.A N LEU 94.A O no hydrogen 2.942 N/A ILE 99.A N ASN 95.A O no hydrogen 3.065 N/A GLN 100.A N ASN 95.A O no hydrogen 3.448 N/A LYS 102.A NZ PHE 98.A O no hydrogen 2.828 N/A ASN 104.A N GLN 101.A OE1 no hydrogen 2.976 N/A LEU 105.A N ASN 104.A OD1 no hydrogen 2.542 N/A LEU 106.A N ALA 103.A O no hydrogen 3.124 N/A SER 107.A OG ASN 104.A O no hydrogen 2.987 N/A PHE 111.A N SER 107.A O no hydrogen 3.018 N/A GLU 112.A N SER 108.A O no hydrogen 2.907 N/A ALA 113.A N SER 109.A O no hydrogen 2.936 N/A THR 114.A N ASN 110.A O no hydrogen 2.933 N/A THR 114.A OG1 ASN 110.A O no hydrogen 3.289 N/A LYS 115.A N PHE 111.A O no hydrogen 2.808 N/A LYS 116.A N GLU 112.A O no hydrogen 2.955 N/A LYS 116.A NZ GLU 112.A O no hydrogen 2.651 N/A SER 117.A N ALA 113.A O no hydrogen 2.958 N/A VAL 118.A N THR 114.A O no hydrogen 2.869 N/A LEU 119.A N LYS 115.A O no hydrogen 2.909 N/A LYS 120.A N LYS 116.A O no hydrogen 2.948 N/A GLN 121.A N SER 117.A O no hydrogen 2.912 N/A VAL 122.A N VAL 118.A O no hydrogen 2.884 N/A GLN 123.A N LEU 119.A O no hydrogen 2.938 N/A ASP 124.A N LYS 120.A O no hydrogen 2.917 N/A PHE 125.A N GLN 121.A O no hydrogen 2.913 N/A GLU 126.A N VAL 122.A O no hydrogen 2.900 N/A GLU 127.A N GLN 123.A O no hydrogen 2.935 N/A GLU 127.A N ASP 124.A O no hydrogen 3.199 N/A ASN 128.A N ASP 124.A O no hydrogen 3.033 N/A ARG 133.A NH2 THR 410.A OG1 no hydrogen 3.269 N/A VAL 134.A N HIS 130.A O no hydrogen 2.910 N/A LEU 135.A N PRO 131.A O no hydrogen 2.943 N/A GLU 136.A N ASN 132.A O no hydrogen 2.915 N/A HIS 137.A N ARG 133.A O no hydrogen 2.902 N/A HIS 137.A ND1 ARG 133.A O no hydrogen 2.906 N/A LEU 138.A N VAL 134.A O no hydrogen 2.866 N/A HIS 139.A N LEU 135.A O no hydrogen 2.967 N/A SER 140.A N GLU 136.A O no hydrogen 2.871 N/A SER 140.A OG GLU 136.A O no hydrogen 3.401 N/A SER 140.A OG SER 149.A O no hydrogen 2.584 N/A THR 141.A N HIS 137.A O no hydrogen 2.897 N/A ALA 142.A N LEU 138.A O no hydrogen 2.922 N/A PHE 143.A N HIS 139.A O no hydrogen 3.379 N/A THR 146.A OG1 GLN 144.A O no hydrogen 3.531 N/A THR 146.A OG1 ASN 145.A O no hydrogen 2.795 N/A LEU 148.A N THR 146.A O no hydrogen 2.621 N/A SER 149.A N THR 146.A O no hydrogen 3.295 N/A SER 149.A OG PHE 143.A O no hydrogen 3.070 N/A SER 149.A OG THR 146.A O no hydrogen 3.265 N/A THR 155.A OG1 SER 158.A OG no hydrogen 2.483 N/A GLU 157.A N GLU 157.A OE1 no hydrogen 2.616 N/A SER 158.A N THR 155.A O no hydrogen 2.888 N/A SER 158.A OG THR 155.A OG1 no hydrogen 2.483 N/A GLU 160.A N GLU 160.A OE1 no hydrogen 2.622 N/A GLU 168.A N VAL 164.A O no hydrogen 3.186 N/A SER 169.A N ALA 165.A O no hydrogen 2.896 N/A SER 169.A OG ALA 165.A O no hydrogen 2.493 N/A PHE 170.A N ASP 166.A O no hydrogen 2.905 N/A ALA 171.A N LEU 167.A O no hydrogen 2.965 N/A ASN 172.A N GLU 168.A O no hydrogen 2.886 N/A ASN 173.A N SER 169.A O no hydrogen 2.910 N/A ASN 173.A N PHE 170.A O no hydrogen 3.260 N/A HIS 174.A N PHE 170.A O no hydrogen 2.927 N/A PHE 175.A N ALA 171.A O no hydrogen 3.192 N/A LEU 176.A N HIS 174.A O no hydrogen 2.915 N/A ASN 177.A ND2 SER 203.A O no hydrogen 2.580 N/A ASN 179.A ND2 HIS 174.A O no hydrogen 3.675 N/A VAL 181.A N VAL 28.A O no hydrogen 3.134 N/A VAL 182.A N VAL 11.A O no hydrogen 3.175 N/A VAL 183.A N GLY 26.A O no hydrogen 2.934 N/A GLU 191.A N GLU 191.A OE1 no hydrogen 2.672 N/A VAL 194.A N GLU 191.A O no hydrogen 3.307 N/A ASN 195.A N GLU 191.A O no hydrogen 2.902 N/A GLN 205.A NE2 ASN 172.A OD1 no hydrogen 2.463 N/A THR 208.A OG1 LYS 209.A O no hydrogen 3.480 N/A LYS 215.A NZ LEU 212.A O no hydrogen 2.893 N/A LYS 215.A NZ LYS 213.A O no hydrogen 3.284 N/A LEU 219.A N ALA 142.A O no hydrogen 3.489 N/A SER 221.A N LEU 219.A O no hydrogen 2.947 N/A SER 221.A OG THR 141.A OG1 no hydrogen 2.920 N/A VAL 223.A N ILE 407.A O no hydrogen 3.363 N/A ARG 224.A NE GLU 222.A OE2 no hydrogen 2.748 N/A ARG 224.A NH1 LEU 416.A O no hydrogen 3.396 N/A ARG 224.A NH2 LEU 416.A O no hydrogen 2.482 N/A LEU 225.A N GLY 409.A O no hydrogen 3.040 N/A ASP 227.A N GLY 411.A O no hydrogen 2.884 N/A TRP 234.A N THR 410.A O no hydrogen 3.261 N/A SER 236.A N ALA 408.A O no hydrogen 3.123 N/A LEU 237.A N PHE 304.A O no hydrogen 2.898 N/A ALA 238.A N ALA 406.A O no hydrogen 3.185 N/A VAL 239.A N TRP 302.A O no hydrogen 2.996 N/A GLU 240.A N GLU 240.A OE1 no hydrogen 2.748 N/A GLY 241.A N GLY 300.A O no hydrogen 3.258 N/A VAL 244.A N TYR 296.A O no hydrogen 3.332 N/A TYR 249.A N SER 246.A O no hydrogen 3.430 N/A ALA 252.A N ASN 248.A O no hydrogen 3.014 N/A LYS 253.A N TYR 249.A O no hydrogen 2.956 N/A LEU 254.A N PHE 250.A O no hydrogen 2.865 N/A ALA 255.A N VAL 251.A O no hydrogen 2.914 N/A ALA 256.A N ALA 252.A O no hydrogen 2.936 N/A GLN 257.A N LYS 253.A O no hydrogen 2.899 N/A ILE 258.A N LEU 254.A O no hydrogen 2.902 N/A GLY 260.A N ALA 256.A O no hydrogen 3.413 N/A SER 261.A OG PHE 289.A O no hydrogen 3.096 N/A ALA 264.A N ASP 287.A O no hydrogen 3.284 N/A PHE 265.A N ASN 263.A OD1 no hydrogen 3.351 N/A GLU 266.A N ASN 263.A O no hydrogen 3.346 N/A ALA 268.A N GLU 266.A OE2 no hydrogen 3.172 N/A SER 269.A N GLU 266.A O no hydrogen 3.155 N/A ARG 270.A NH1 ALA 264.A O no hydrogen 2.722 N/A LEU 277.A N ILE 274.A O no hydrogen 3.061 N/A ASN 279.A N LYS 275.A O no hydrogen 2.920 N/A ILE 280.A N LEU 276.A O no hydrogen 2.874 N/A ILE 280.A N LEU 277.A O no hydrogen 3.285 N/A GLN 281.A N LEU 277.A O no hydrogen 2.916 N/A TYR 283.A N ILE 280.A O no hydrogen 3.263 N/A ASP 287.A N ALA 307.A O no hydrogen 3.071 N/A PHE 289.A N TYR 262.A O no hydrogen 3.232 N/A ASN 290.A N SER 305.A O no hydrogen 3.264 N/A HIS 291.A ND1 GLY 260.A O no hydrogen 3.189 N/A LEU 294.A N LEU 301.A O no hydrogen 2.879 N/A SER 295.A OG GLU 242.A O no hydrogen 3.134 N/A TYR 296.A N SER 299.A O no hydrogen 3.190 N/A TYR 296.A OH HIS 139.A NE2 no hydrogen 2.819 N/A SER 299.A OG GLY 300.A O no hydrogen 3.564 N/A LEU 301.A N LEU 294.A O no hydrogen 2.722 N/A TRP 302.A N VAL 239.A O no hydrogen 3.365 N/A GLY 303.A N PHE 292.A O no hydrogen 2.766 N/A PHE 304.A N LEU 237.A O no hydrogen 2.906 N/A THR 306.A N ILE 235.A O no hydrogen 3.325 N/A THR 306.A OG1 ASN 288.A O no hydrogen 3.017 N/A THR 308.A N ALA 233.A O no hydrogen 3.300 N/A THR 308.A OG1 ASN 310.A O no hydrogen 2.597 N/A ARG 309.A NH1 ASP 287.A OD2 no hydrogen 2.985 N/A MET 313.A N ASN 310.A OD1 no hydrogen 2.958 N/A LEU 317.A N MET 313.A O no hydrogen 3.151 N/A ILE 318.A N ILE 314.A O no hydrogen 2.963 N/A HIS 319.A N ASP 315.A O no hydrogen 2.901 N/A PHE 320.A N ASP 316.A O no hydrogen 2.903 N/A THR 321.A N LEU 317.A O no hydrogen 2.965 N/A THR 321.A OG1 LEU 317.A O no hydrogen 2.972 N/A LEU 322.A N ILE 318.A O no hydrogen 2.935 N/A LYS 323.A N HIS 319.A O no hydrogen 2.881 N/A GLN 324.A N PHE 320.A O no hydrogen 2.939 N/A TRP 325.A N THR 321.A O no hydrogen 2.956 N/A TRP 325.A NE1 HIS 291.A NE2 no hydrogen 3.233 N/A ASN 326.A N LEU 322.A O no hydrogen 2.892 N/A ARG 327.A N LYS 323.A O no hydrogen 2.894 N/A ARG 327.A NE GLN 324.A OE1 no hydrogen 3.195 N/A ARG 327.A NH2 GLU 336.A OE1 no hydrogen 3.171 N/A ARG 327.A NH2 GLU 336.A OE2 no hydrogen 3.409 N/A LEU 328.A N GLN 324.A O no hydrogen 2.941 N/A LEU 328.A N TRP 325.A O no hydrogen 3.138 N/A THR 329.A N ASN 326.A O no hydrogen 3.342 N/A ILE 330.A N ARG 327.A O no hydrogen 3.389 N/A SER 331.A N ARG 327.A O no hydrogen 3.260 N/A VAL 337.A N THR 333.A O no hydrogen 3.294 N/A GLU 338.A N ASP 334.A O no hydrogen 2.910 N/A ARG 339.A N THR 335.A O no hydrogen 2.914 N/A ALA 340.A N GLU 336.A O no hydrogen 2.903 N/A LYS 341.A N VAL 337.A O no hydrogen 2.866 N/A LYS 341.A NZ ASP 385.A O no hydrogen 2.970 N/A LYS 341.A NZ ASP 385.A OD1 no hydrogen 3.346 N/A SER 342.A N GLU 338.A O no hydrogen 2.974 N/A LEU 343.A N ARG 339.A O no hydrogen 2.908 N/A LEU 344.A N ALA 340.A O no hydrogen 2.857 N/A LYS 345.A N LYS 341.A O no hydrogen 2.903 N/A LYS 345.A NZ ASP 385.A OD1 no hydrogen 2.795 N/A LYS 345.A NZ ASP 385.A OD2 no hydrogen 3.017 N/A LEU 346.A N SER 342.A O no hydrogen 2.978 N/A GLN 347.A N LEU 343.A O no hydrogen 2.866 N/A LEU 348.A N LEU 344.A O no hydrogen 2.891 N/A GLY 349.A N LYS 345.A O no hydrogen 2.926 N/A GLN 350.A N LEU 346.A O no hydrogen 2.927 N/A LEU 351.A N GLN 347.A O no hydrogen 2.911 N/A TYR 352.A N LEU 348.A O no hydrogen 2.898 N/A ASN 356.A N SER 354.A OG no hydrogen 3.287 N/A ASN 356.A ND2 ASN 359.A OD1 no hydrogen 3.250 N/A ASP 360.A N ASN 356.A O no hydrogen 3.401 N/A ALA 361.A N PRO 357.A O no hydrogen 2.894 N/A ASN 362.A N VAL 358.A O no hydrogen 2.908 N/A LEU 363.A N ASN 359.A O no hydrogen 2.941 N/A LEU 364.A N ASP 360.A O no hydrogen 2.877 N/A GLY 365.A N ALA 361.A O no hydrogen 2.920 N/A ALA 366.A N ASN 362.A O no hydrogen 2.895 N/A GLU 367.A N LEU 363.A O no hydrogen 2.930 N/A VAL 368.A N LEU 364.A O no hydrogen 2.898 N/A VAL 368.A N GLY 365.A O no hydrogen 3.295 N/A LEU 369.A N GLY 365.A O no hydrogen 2.934 N/A LYS 371.A NZ ASN 245.A OD1 no hydrogen 2.965 N/A GLU 379.A N GLU 379.A OE1 no hydrogen 2.669 N/A ALA 380.A N SER 376.A O no hydrogen 2.989 N/A PHE 381.A N LEU 377.A O no hydrogen 2.883 N/A LYS 382.A N GLY 378.A O no hydrogen 2.927 N/A LYS 383.A N GLU 379.A O no hydrogen 2.933 N/A LYS 383.A NZ GLU 379.A O no hydrogen 3.325 N/A ILE 384.A N ALA 380.A O no hydrogen 2.870 N/A ASP 385.A N PHE 381.A O no hydrogen 2.909 N/A ALA 386.A N LYS 382.A O no hydrogen 2.927 N/A ILE 387.A N ILE 384.A O no hydrogen 3.141 N/A VAL 392.A N THR 388.A O no hydrogen 3.426 N/A LYS 393.A N VAL 389.A O no hydrogen 2.928 N/A LYS 393.A NZ ILE 330.A O no hydrogen 2.718 N/A ALA 394.A N LYS 390.A O no hydrogen 2.902 N/A TRP 395.A N ASP 391.A O no hydrogen 2.932 N/A TRP 395.A NE1 GLU 242.A OE2 no hydrogen 2.309 N/A ALA 396.A N VAL 392.A O no hydrogen 2.900 N/A GLY 397.A N LYS 393.A O no hydrogen 2.919 N/A LYS 398.A N ALA 394.A O no hydrogen 2.923 N/A ARG 399.A N TRP 395.A O no hydrogen 2.917 N/A LEU 400.A N ALA 396.A O no hydrogen 2.875 N/A GLN 403.A NE2 TRP 401.A O no hydrogen 3.595 N/A ALA 406.A N ALA 238.A O no hydrogen 3.232 N/A ALA 408.A N SER 236.A O no hydrogen 3.177 N/A THR 410.A N TRP 234.A O no hydrogen 3.118 N/A THR 410.A OG1 LEU 225.A O no hydrogen 3.123 N/A THR 410.A OG1 ASP 227.A OD1 no hydrogen 3.520 N/A GLY 411.A N ASP 227.A OD1 no hydrogen 2.898 N/A GLN 412.A NE2 LEU 230.A O no hydrogen 2.790 N/A TYR 419.A N ASP 418.A OD1 no hydrogen 2.396 N/A TYR 419.A OH ASP 404.A OD1 no hydrogen 2.955 N/A TYR 419.A OH ILE 405.A O no hydrogen 2.320 N/A ARG 423.A N TYR 419.A O no hydrogen 3.130 N/A ARG 423.A NH1 ASP 404.A OD1 no hydrogen 2.564 N/A SER 424.A N MET 420.A O no hydrogen 2.891 N/A SER 424.A OG ARG 421.A O no hydrogen 3.184 N/A SER 424.A OG ASP 425.A OD1 no hydrogen 3.131 N/A ASP 425.A N ILE 422.A O no hydrogen 3.341 N/A MET 426.A N ARG 423.A O no hydrogen 3.433 N/A SER 427.A N SER 424.A O no hydrogen 3.441 N/A MET 428.A N SER 424.A O no hydrogen 3.158 N/A