Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8edh_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 2.A N LYS 12.A O no hydrogen 2.895 N/A THR 4.A OG1 SER 5.A O no hydrogen 2.994 N/A THR 4.A OG1 PHE 10.A O no hydrogen 2.995 N/A SER 5.A N PHE 10.A O no hydrogen 2.985 N/A SER 5.A OG SER 7.A OG no hydrogen 2.794 N/A SER 7.A OG SER 5.A OG no hydrogen 2.794 N/A GLY 8.A N SER 5.A O no hydrogen 2.800 N/A ARG 9.A N SER 7.A OG no hydrogen 3.251 N/A ARG 9.A NE ASP 30.A OD1 no hydrogen 2.850 N/A ARG 9.A NE ASP 30.A OD2 no hydrogen 3.419 N/A ARG 9.A NH2 ASP 30.A OD2 no hydrogen 2.857 N/A PHE 10.A N SER 5.A OG no hydrogen 3.145 N/A LEU 11.A N LEU 29.A O no hydrogen 2.977 N/A LYS 12.A N ALA 3.A O no hydrogen 2.882 N/A LYS 12.A NZ GLU 41.A OE1 no hydrogen 3.370 N/A PHE 13.A N LYS 27.A O no hydrogen 3.277 N/A LEU 17.A N VAL 25.A O no hydrogen 2.669 N/A LYS 23.A NZ ASP 158.A OD2 no hydrogen 3.529 N/A THR 24.A N GLU 41.A O no hydrogen 2.864 N/A VAL 25.A N GLY 18.A O no hydrogen 3.353 N/A TYR 26.A N TRP 39.A O no hydrogen 3.016 N/A LYS 27.A N ILE 15.A O no hydrogen 3.108 N/A GLY 28.A N VAL 37.A O no hydrogen 2.874 N/A LEU 29.A N LEU 11.A O no hydrogen 2.978 N/A ASP 30.A N VAL 35.A O no hydrogen 3.168 N/A THR 31.A N ARG 9.A O no hydrogen 2.853 N/A THR 31.A OG1 ARG 9.A O no hydrogen 3.111 N/A GLU 32.A N ASP 30.A OD1 no hydrogen 3.256 N/A THR 33.A OG1 ASP 30.A OD2 no hydrogen 2.703 N/A VAL 37.A N GLY 28.A O no hydrogen 2.698 N/A ALA 38.A N THR 91.A O no hydrogen 3.023 N/A TRP 39.A N TYR 26.A O no hydrogen 2.913 N/A TRP 39.A NE1 GLU 41.A OE1 no hydrogen 3.094 N/A CYS 40.A N LEU 89.A O no hydrogen 2.981 N/A GLU 41.A N THR 24.A O no hydrogen 2.871 N/A LEU 42.A N ILE 87.A O no hydrogen 2.924 N/A GLN 43.A N PHE 22.A O no hydrogen 3.266 N/A ASP 44.A N LYS 85.A O no hydrogen 3.122 N/A LYS 46.A NZ MET 165.A O no hydrogen 2.997 N/A LEU 47.A N ASP 44.A O no hydrogen 2.560 N/A THR 48.A N ASP 44.A OD1 no hydrogen 3.139 N/A THR 48.A OG1 LYS 49.A O no hydrogen 3.104 N/A GLN 52.A N LYS 49.A O no hydrogen 2.561 N/A GLN 52.A NE2 ASP 44.A OD2 no hydrogen 3.445 N/A GLN 53.A N ALA 50.A O no hydrogen 3.365 N/A PHE 55.A N GLU 51.A O no hydrogen 3.345 N/A LYS 56.A N GLN 52.A O no hydrogen 2.984 N/A GLU 57.A N GLN 53.A O no hydrogen 3.141 N/A GLU 58.A N ARG 54.A O no hydrogen 2.889 N/A ALA 59.A N PHE 55.A O no hydrogen 2.515 N/A GLU 60.A N LYS 56.A O no hydrogen 2.770 N/A MET 61.A N GLU 57.A O no hydrogen 3.045 N/A LEU 62.A N GLU 58.A O no hydrogen 2.968 N/A LYS 63.A N ALA 59.A O no hydrogen 3.259 N/A LYS 63.A NZ ASP 75.A OD1 no hydrogen 3.356 N/A GLY 64.A N MET 61.A O no hydrogen 2.872 N/A LEU 65.A N LEU 62.A O no hydrogen 3.296 N/A ASN 69.A N HIS 67.A ND1 no hydrogen 3.265 N/A ILE 70.A N HIS 67.A O no hydrogen 3.122 N/A VAL 71.A N ILE 156.A O no hydrogen 2.925 N/A ARG 72.A N GLU 92.A OE1 no hydrogen 3.206 N/A TYR 74.A N VAL 90.A O no hydrogen 2.642 N/A ASP 75.A N VAL 90.A O no hydrogen 3.153 N/A SER 76.A N ASP 75.A OD1 no hydrogen 3.021 N/A SER 76.A OG VAL 88.A O no hydrogen 3.560 N/A TRP 77.A N VAL 88.A O no hydrogen 3.031 N/A LYS 84.A N LEU 81.A O no hydrogen 3.289 N/A CYS 86.A N SER 79.A O no hydrogen 2.918 N/A CYS 86.A SG SER 79.A O no hydrogen 3.719 N/A ILE 87.A N LEU 42.A O no hydrogen 3.120 N/A VAL 88.A N TRP 77.A O no hydrogen 3.093 N/A LEU 89.A N CYS 40.A O no hydrogen 2.778 N/A VAL 90.A N ASP 75.A O no hydrogen 2.641 N/A THR 91.A N ALA 38.A O no hydrogen 3.286 N/A GLU 92.A N ARG 72.A O no hydrogen 2.974 N/A SER 96.A OG THR 148.A O no hydrogen 2.945 N/A THR 98.A N THR 101.A OG1 no hydrogen 3.209 N/A LEU 99.A N ILE 145.A O no hydrogen 3.030 N/A LYS 100.A N CYS 142.A O no hydrogen 3.377 N/A THR 101.A N THR 98.A OG1 no hydrogen 3.176 N/A THR 101.A OG1 THR 98.A O no hydrogen 3.199 N/A TYR 102.A N THR 98.A O no hydrogen 3.250 N/A LEU 103.A N LEU 99.A O no hydrogen 2.878 N/A ARG 105.A N THR 101.A O no hydrogen 3.327 N/A PHE 106.A N TYR 102.A O no hydrogen 3.090 N/A LYS 107.A N LEU 103.A O no hydrogen 2.355 N/A LYS 107.A NZ SER 193.A O no hydrogen 3.542 N/A VAL 113.A N LYS 110.A O no hydrogen 2.789 N/A LEU 114.A N LYS 110.A O no hydrogen 3.170 N/A ARG 115.A N PRO 111.A O no hydrogen 3.268 N/A ARG 115.A NE PHE 253.A O no hydrogen 3.063 N/A SER 116.A N LYS 112.A O no hydrogen 3.283 N/A SER 116.A OG LYS 112.A O no hydrogen 3.369 N/A TRP 117.A N VAL 113.A O no hydrogen 2.939 N/A TRP 117.A NE1 GLY 152.A O no hydrogen 2.930 N/A CYS 118.A N LEU 114.A O no hydrogen 2.906 N/A CYS 118.A SG LEU 114.A O no hydrogen 3.120 N/A ARG 119.A N ARG 115.A O no hydrogen 2.878 N/A GLN 120.A N SER 116.A O no hydrogen 3.187 N/A GLN 120.A NE2 SER 116.A O no hydrogen 3.240 N/A ILE 121.A N TRP 117.A O no hydrogen 2.958 N/A LEU 122.A N CYS 118.A O no hydrogen 2.972 N/A LYS 123.A N ARG 119.A O no hydrogen 2.906 N/A GLY 124.A N GLN 120.A O no hydrogen 2.913 N/A LEU 125.A N ILE 121.A O no hydrogen 2.871 N/A GLN 126.A N LEU 122.A O no hydrogen 2.717 N/A PHE 127.A N LYS 123.A O no hydrogen 3.145 N/A LEU 128.A N GLY 124.A O no hydrogen 3.056 N/A HIS 129.A N LEU 125.A O no hydrogen 2.843 N/A HIS 129.A NE2 ASP 179.A OD2 no hydrogen 2.947 N/A THR 130.A N GLN 126.A O no hydrogen 3.003 N/A THR 130.A N PHE 127.A O no hydrogen 3.083 N/A THR 130.A OG1 GLN 126.A O no hydrogen 2.862 N/A THR 130.A OG1 PHE 127.A O no hydrogen 3.196 N/A ARG 131.A N LEU 128.A O no hydrogen 3.467 N/A ARG 131.A NE PHE 127.A O no hydrogen 2.729 N/A ILE 135.A N LEU 128.A O no hydrogen 2.760 N/A HIS 137.A N ASP 179.A OD2 no hydrogen 2.913 N/A HIS 137.A NE2 GLY 157.A O no hydrogen 2.870 N/A ARG 138.A N ASP 179.A OD1 no hydrogen 3.020 N/A ARG 138.A NH1 GLU 58.A OE2 no hydrogen 2.625 N/A LYS 141.A N ASN 144.A OD1 no hydrogen 3.223 N/A CYS 142.A SG GLU 189.A OE1 no hydrogen 3.112 N/A ASN 144.A N LYS 141.A O no hydrogen 3.351 N/A ASN 144.A ND2 ASP 139.A O no hydrogen 3.038 N/A PHE 146.A N LYS 155.A O no hydrogen 2.851 N/A ILE 147.A N GLY 97.A O no hydrogen 3.204 N/A THR 148.A N SER 153.A O no hydrogen 2.690 N/A THR 148.A OG1 SER 153.A O no hydrogen 2.899 N/A THR 148.A OG1 SER 153.A OG no hydrogen 3.232 N/A SER 153.A N THR 148.A OG1 no hydrogen 3.252 N/A SER 153.A OG THR 148.A OG1 no hydrogen 3.232 N/A VAL 154.A N GLN 120.A OE1 no hydrogen 2.682 N/A LYS 155.A N PHE 146.A O no hydrogen 2.699 N/A LYS 155.A NZ GLU 92.A OE1 no hydrogen 2.899 N/A LYS 155.A NZ GLU 92.A OE2 no hydrogen 3.159 N/A ILE 156.A N ASN 69.A O no hydrogen 2.805 N/A GLY 157.A N ASN 144.A O no hydrogen 2.826 N/A ALA 162.A N LEU 159.A O no hydrogen 3.354 N/A THR 163.A N GLY 160.A O no hydrogen 2.842 N/A THR 163.A OG1 GLU 58.A OE1 no hydrogen 2.486 N/A THR 163.A OG1 GLU 58.A OE2 no hydrogen 2.582 N/A THR 163.A OG1 GLY 160.A O no hydrogen 3.530 N/A LEU 164.A N LEU 161.A O no hydrogen 3.086 N/A GLU 171.A N GLU 171.A OE1 no hydrogen 2.706 N/A MET 172.A N ALA 169.A O no hydrogen 2.887 N/A TYR 173.A N PRO 170.A O no hydrogen 3.042 N/A GLU 176.A N GLU 176.A OE1 no hydrogen 2.932 N/A SER 177.A N ASP 175.A OD2 no hydrogen 3.447 N/A SER 177.A OG ASP 175.A OD1 no hydrogen 3.243 N/A SER 177.A OG ASP 175.A OD2 no hydrogen 3.100 N/A VAL 178.A N ASP 175.A O no hydrogen 2.998 N/A ASP 179.A N GLU 176.A O no hydrogen 3.359 N/A TYR 181.A N SER 177.A O no hydrogen 3.106 N/A ALA 182.A N VAL 178.A O no hydrogen 3.154 N/A PHE 183.A N ASP 179.A O no hydrogen 2.871 N/A GLY 184.A N VAL 180.A O no hydrogen 2.965 N/A MET 185.A N TYR 181.A O no hydrogen 3.177 N/A CYS 186.A N ALA 182.A O no hydrogen 2.908 N/A CYS 186.A SG ALA 182.A O no hydrogen 3.934 N/A MET 187.A N PHE 183.A O no hydrogen 2.837 N/A LEU 188.A N GLY 184.A O no hydrogen 2.975 N/A GLU 189.A N MET 185.A O no hydrogen 3.113 N/A MET 190.A N CYS 186.A O no hydrogen 2.812 N/A ALA 191.A N MET 187.A O no hydrogen 2.805 N/A THR 192.A N LEU 188.A O no hydrogen 2.711 N/A THR 192.A OG1 LEU 188.A O no hydrogen 2.618 N/A THR 192.A OG1 GLU 194.A O no hydrogen 3.112 N/A SER 193.A OG LYS 107.A O no hydrogen 2.818 N/A TYR 197.A OH ILE 214.A O no hydrogen 2.367 N/A SER 198.A OG GLU 194.A OE1 no hydrogen 3.478 N/A SER 198.A OG TYR 195.A O no hydrogen 2.244 N/A CYS 200.A N TYR 197.A O no hydrogen 3.341 N/A CYS 200.A SG TYR 197.A O no hydrogen 3.651 N/A CYS 200.A SG GLU 199.A OE1 no hydrogen 3.751 N/A ILE 206.A N ALA 203.A O no hydrogen 2.917 N/A TYR 207.A N ALA 203.A O no hydrogen 2.963 N/A ARG 208.A N ALA 204.A O no hydrogen 2.719 N/A LYS 209.A N GLN 205.A O no hydrogen 3.433 N/A LYS 209.A NZ GLU 199.A OE1 no hydrogen 2.700 N/A VAL 210.A N ILE 206.A O no hydrogen 2.877 N/A THR 211.A N TYR 207.A O no hydrogen 2.951 N/A THR 211.A OG1 TYR 207.A O no hydrogen 2.349 N/A SER 212.A N ARG 208.A O no hydrogen 3.068 N/A SER 212.A OG ARG 208.A O no hydrogen 2.643 N/A SER 212.A OG LYS 209.A O no hydrogen 3.364 N/A GLY 213.A N VAL 210.A O no hydrogen 3.033 N/A ILE 214.A N LYS 209.A O no hydrogen 2.588 N/A ALA 217.A N GLU 199.A OE2 no hydrogen 2.804 N/A SER 218.A OG GLU 194.A OE1 no hydrogen 3.317 N/A PHE 219.A N PRO 216.A O no hydrogen 2.958 N/A ASN 220.A N ALA 217.A O no hydrogen 3.038 N/A LYS 221.A N SER 218.A O no hydrogen 2.893 N/A VAL 222.A N PHE 219.A O no hydrogen 3.313 N/A ASP 224.A N THR 223.A OG1 no hydrogen 2.711 N/A GLU 226.A N ASP 224.A OD1 no hydrogen 2.726 N/A LYS 228.A N ASP 224.A O no hydrogen 3.436 N/A GLU 229.A N PRO 225.A O no hydrogen 2.746 N/A ILE 231.A N VAL 227.A O no hydrogen 2.810 N/A GLU 232.A N LYS 228.A O no hydrogen 2.841 N/A GLY 233.A N GLU 229.A O no hydrogen 3.186 N/A CYS 234.A N ILE 231.A O no hydrogen 3.204 N/A CYS 234.A SG ILE 230.A O no hydrogen 3.699 N/A ILE 235.A N ILE 231.A O no hydrogen 3.089 N/A ARG 236.A NH2 GLU 232.A OE1 no hydrogen 3.295 N/A GLU 241.A N ASN 238.A O no hydrogen 3.023 N/A ARG 242.A NE ARG 236.A O no hydrogen 2.729 N/A ARG 242.A NH1 GLU 171.A OE1 no hydrogen 3.225 N/A ARG 242.A NH1 GLU 171.A OE2 no hydrogen 2.766 N/A ARG 242.A NH1 SER 177.A O no hydrogen 3.331 N/A ARG 242.A NH2 GLU 171.A OE1 no hydrogen 2.690 N/A ARG 242.A NH2 ARG 236.A O no hydrogen 3.130 N/A LEU 243.A N GLY 233.A O no hydrogen 3.002 N/A SER 244.A N ASP 247.A OD2 no hydrogen 2.980 N/A LEU 248.A N SER 244.A O no hydrogen 3.199 N/A LEU 249.A N ILE 245.A O no hydrogen 2.731 N/A ASN 250.A N ARG 246.A O no hydrogen 2.741 N/A HIS 251.A N LEU 248.A O no hydrogen 3.270 N/A HIS 251.A NE2 GLU 229.A OE2 no hydrogen 2.859 N/A PHE 253.A N HIS 251.A ND1 no hydrogen 2.834 N/A