Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8ee8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 1.A N SER 142.A OG no hydrogen 2.979 N/A ILE 1.A N MET 151.A O no hydrogen 2.422 N/A ARG 2.A NH2 MET 151.A O no hydrogen 2.638 N/A CYS 3.A SG ASP 42.A OD1 no hydrogen 3.550 N/A VAL 6.A N CYS 3.A O no hydrogen 3.179 N/A ASN 8.A ND2 GLU 26.A OE1 no hydrogen 2.312 N/A ARG 9.A NH1 ASP 42.A OD2 no hydrogen 3.316 N/A ARG 9.A NH2 GLU 377.A OE1 no hydrogen 3.054 N/A ASP 10.A N CYS 30.A O no hydrogen 3.020 N/A GLY 14.A N MET 34.A O no hydrogen 2.771 N/A THR 19.A OG1 ASP 296.A OD1 no hydrogen 2.764 N/A VAL 23.A N CYS 291.A O no hydrogen 3.314 N/A LEU 25.A N LEU 289.A O no hydrogen 2.901 N/A GLY 29.A N GLU 26.A O no hydrogen 3.487 N/A CYS 30.A N ASN 8.A O no hydrogen 3.053 N/A CYS 30.A SG VAL 31.A O no hydrogen 3.805 N/A CYS 30.A SG ASP 42.A OD1 no hydrogen 3.374 N/A CYS 30.A SG ILE 43.A O no hydrogen 3.090 N/A VAL 31.A N ILE 43.A O no hydrogen 3.243 N/A THR 32.A N ASP 10.A O no hydrogen 2.716 N/A THR 32.A OG1 ASP 10.A O no hydrogen 3.498 N/A VAL 33.A N VAL 41.A O no hydrogen 3.166 N/A MET 34.A N VAL 12.A O no hydrogen 3.374 N/A LYS 38.A NZ MET 295.A O no hydrogen 1.534 N/A LYS 38.A NZ LEU 298.A O no hydrogen 2.905 N/A THR 40.A OG1 PRO 39.A O no hydrogen 2.359 N/A THR 40.A OG1 THR 40.A O no hydrogen 2.438 N/A THR 40.A OG1 ILE 359.A O no hydrogen 3.001 N/A ASP 42.A N SER 142.A O no hydrogen 2.405 N/A ILE 43.A N VAL 31.A O no hydrogen 3.254 N/A GLU 44.A N MET 140.A O no hydrogen 2.896 N/A VAL 46.A N ARG 138.A O no hydrogen 3.020 N/A THR 47.A N ARG 138.A O no hydrogen 3.444 N/A THR 49.A N GLU 136.A O no hydrogen 2.736 N/A THR 49.A OG1 GLU 136.A O no hydrogen 3.033 N/A VAL 50.A N GLY 282.A O no hydrogen 2.864 N/A SER 51.A N ASN 134.A O no hydrogen 3.195 N/A SER 51.A OG ASN 134.A O no hydrogen 2.931 N/A SER 51.A OG ASN 134.A OD1 no hydrogen 2.637 N/A VAL 56.A N GLY 127.A O no hydrogen 2.738 N/A ARG 57.A N GLY 127.A O no hydrogen 3.296 N/A ARG 57.A NH1 TYR 59.A OH no hydrogen 2.961 N/A SER 58.A N HIS 226.A O no hydrogen 3.247 N/A TYR 59.A N MET 125.A O no hydrogen 2.951 N/A TYR 59.A OH PHE 218.A O no hydrogen 2.619 N/A TYR 59.A OH HIS 219.A O no hydrogen 3.428 N/A CYS 60.A N PRO 224.A O no hydrogen 2.867 N/A CYS 60.A SG GLU 62.A O no hydrogen 3.258 N/A CYS 60.A SG LYS 123.A O no hydrogen 3.525 N/A TYR 61.A N LYS 123.A O no hydrogen 3.239 N/A SER 64.A N ALA 120.A O no hydrogen 2.787 N/A SER 66.A N LYS 118.A O no hydrogen 3.220 N/A ALA 69.A N CYS 116.A O no hydrogen 3.062 N/A SER 70.A OG THR 115.A OG1 no hydrogen 2.717 N/A ASP 71.A N VAL 114.A O no hydrogen 2.838 N/A SER 72.A OG SER 112.A O no hydrogen 3.482 N/A ARG 73.A N SER 112.A O no hydrogen 2.795 N/A GLN 77.A N CYS 74.A O no hydrogen 3.266 N/A ALA 80.A N SER 112.A OG no hydrogen 2.990 N/A TYR 81.A N ASP 71.A OD2 no hydrogen 2.936 N/A TYR 81.A OH ASP 83.A OD1 no hydrogen 2.438 N/A LEU 82.A N GLN 85.A OE1 no hydrogen 3.142 N/A GLN 85.A N LEU 82.A O no hydrogen 3.269 N/A ASP 87.A N LYS 84.A O no hydrogen 3.229 N/A GLN 89.A N ASP 87.A OD1 no hydrogen 2.819 N/A TYR 90.A N ASP 87.A O no hydrogen 3.358 N/A TYR 90.A OH ASP 67.A OD2 no hydrogen 3.405 N/A VAL 91.A N ALA 117.A O no hydrogen 2.817 N/A CYS 92.A SG LYS 84.A O no hydrogen 4.031 N/A CYS 92.A SG GLN 85.A O no hydrogen 3.893 N/A LYS 93.A N THR 115.A O no hydrogen 3.107 N/A LYS 93.A NZ PHE 245.A O no hydrogen 3.493 N/A THR 95.A N LEU 113.A O no hydrogen 2.909 N/A VAL 97.A N GLY 111.A O no hydrogen 2.857 N/A ARG 99.A N GLY 109.A O no hydrogen 2.761 N/A ARG 99.A NH2 SER 72.A OG no hydrogen 2.616 N/A ASN 103.A N GLY 100.A O no hydrogen 2.642 N/A CYS 105.A SG GLY 100.A O no hydrogen 3.072 N/A CYS 105.A SG LEU 107.A O no hydrogen 4.009 N/A GLY 109.A N ARG 99.A O no hydrogen 2.968 N/A GLY 111.A N VAL 97.A O no hydrogen 2.676 N/A SER 112.A OG GLU 79.A OE1 no hydrogen 3.361 N/A LEU 113.A N THR 95.A O no hydrogen 3.121 N/A VAL 114.A N ASP 71.A O no hydrogen 2.834 N/A THR 115.A N LYS 93.A O no hydrogen 3.230 N/A THR 115.A OG1 SER 70.A OG no hydrogen 2.717 N/A CYS 116.A N ALA 69.A O no hydrogen 2.890 N/A ALA 117.A N VAL 91.A O no hydrogen 2.948 N/A LYS 118.A N SER 66.A O no hydrogen 2.643 N/A PHE 119.A N GLN 89.A O no hydrogen 2.729 N/A ALA 120.A N SER 64.A O no hydrogen 3.205 N/A CYS 121.A SG GLU 62.A O no hydrogen 3.897 N/A CYS 121.A SG LYS 123.A O no hydrogen 3.329 N/A SER 122.A N GLU 62.A O no hydrogen 2.928 N/A LYS 123.A N GLU 62.A O no hydrogen 3.250 N/A MET 125.A N TYR 59.A O no hydrogen 2.692 N/A THR 126.A N THR 205.A O no hydrogen 2.926 N/A GLY 127.A N ARG 57.A O no hydrogen 2.948 N/A LYS 128.A N TYR 203.A O no hydrogen 2.644 N/A SER 129.A N ALA 54.A O no hydrogen 2.823 N/A ASN 134.A N GLN 131.A O no hydrogen 2.841 N/A TYR 137.A N ILE 169.A O no hydrogen 2.867 N/A ARG 138.A N THR 47.A O no hydrogen 2.614 N/A ILE 139.A N VAL 167.A O no hydrogen 2.787 N/A MET 140.A N GLU 44.A O no hydrogen 2.808 N/A LEU 141.A N ALA 165.A O no hydrogen 2.743 N/A SER 142.A N ASP 42.A O no hydrogen 2.679 N/A VAL 143.A N ASN 163.A O no hydrogen 2.628 N/A HIS 144.A N PRO 39.A O no hydrogen 3.386 N/A HIS 144.A ND1 THR 360.A OG1 no hydrogen 3.018 N/A HIS 144.A NE2 ASP 42.A OD2 no hydrogen 2.899 N/A GLN 147.A NE2 SER 142.A OG no hydrogen 3.285 N/A MET 151.A N HIS 148.A O no hydrogen 3.075 N/A ILE 152.A N SER 149.A O no hydrogen 3.070 N/A THR 156.A N ASN 154.A OD1 no hydrogen 3.038 N/A THR 156.A OG1 ASN 154.A OD1 no hydrogen 3.056 N/A HIS 158.A ND1 ASP 155.A O no hydrogen 2.766 N/A GLU 159.A N GLU 159.A OE1 no hydrogen 2.385 N/A THR 160.A OG1 GLY 157.A O no hydrogen 2.850 N/A ASP 161.A N GLY 157.A O no hydrogen 3.232 N/A ASN 163.A N ASP 161.A OD1 no hydrogen 2.826 N/A ASN 163.A ND2 ASP 161.A OD1 no hydrogen 3.049 N/A ARG 164.A NH1 ASP 161.A OD2 no hydrogen 2.667 N/A ALA 165.A N LEU 141.A O no hydrogen 2.611 N/A LYS 166.A NZ HIS 158.A NE2 no hydrogen 3.007 N/A VAL 167.A N ILE 139.A O no hydrogen 2.851 N/A ILE 169.A N TYR 137.A O no hydrogen 2.875 N/A THR 170.A OG1 SER 173.A OG no hydrogen 2.279 N/A SER 173.A N THR 170.A O no hydrogen 3.033 N/A SER 173.A OG THR 170.A OG1 no hydrogen 2.279 N/A ALA 176.A N LEU 188.A O no hydrogen 2.672 N/A ALA 178.A N LEU 186.A O no hydrogen 2.867 N/A LEU 180.A N GLY 184.A O no hydrogen 2.955 N/A PHE 183.A N LEU 180.A O no hydrogen 2.735 N/A GLY 184.A N GLY 181.A O no hydrogen 3.320 N/A SER 185.A N LYS 297.A O no hydrogen 3.058 N/A SER 185.A OG GLU 177.A OE2 no hydrogen 2.826 N/A LEU 186.A N ALA 178.A O no hydrogen 3.238 N/A GLY 187.A N LYS 294.A O no hydrogen 3.026 N/A LEU 188.A N ALA 176.A O no hydrogen 2.589 N/A ASP 189.A N ARG 292.A O no hydrogen 2.976 N/A CYS 190.A N PRO 174.A O no hydrogen 3.220 N/A GLU 191.A N LYS 290.A O no hydrogen 3.414 N/A THR 194.A OG1 THR 194.A O no hydrogen 2.652 N/A THR 194.A OG1 ASP 197.A OD1 no hydrogen 3.285 N/A PHE 198.A N LEU 196.A O no hydrogen 2.752 N/A SER 199.A OG SER 199.A O no hydrogen 2.509 N/A LEU 201.A N ASP 200.A OD1 no hydrogen 2.544 N/A TYR 203.A N LYS 128.A O no hydrogen 2.612 N/A LEU 204.A N TRP 211.A O no hydrogen 2.808 N/A THR 205.A N THR 126.A O no hydrogen 2.750 N/A THR 205.A OG1 HIS 210.A ND1 no hydrogen 3.053 N/A MET 206.A N LYS 209.A O no hydrogen 2.891 N/A LYS 209.A N MET 206.A O no hydrogen 2.782 N/A HIS 210.A ND1 THR 205.A OG1 no hydrogen 3.053 N/A TRP 211.A N LEU 204.A O no hydrogen 2.782 N/A VAL 213.A N TYR 202.A O no hydrogen 3.063 N/A LYS 215.A N ASP 200.A OD1 no hydrogen 2.960 N/A LYS 215.A NZ SER 199.A O no hydrogen 3.498 N/A PHE 218.A N HIS 214.A O no hydrogen 3.389 N/A HIS 219.A N LYS 215.A O no hydrogen 2.912 N/A ASP 220.A N GLU 216.A O no hydrogen 3.202 N/A LEU 223.A N ILE 221.A O no hydrogen 2.827 N/A TRP 225.A N ASN 237.A O no hydrogen 3.085 N/A TRP 225.A NE1 ASN 238.A OD1 no hydrogen 3.146 N/A HIS 226.A N SER 58.A O no hydrogen 3.282 N/A ASN 237.A N TRP 225.A O no hydrogen 2.736 N/A ASN 237.A ND2 TRP 225.A O no hydrogen 3.458 N/A LYS 239.A NZ THR 88.A O no hydrogen 3.231 N/A LYS 239.A NZ TRP 236.A O no hydrogen 2.795 N/A GLU 240.A N GLU 240.A OE1 no hydrogen 2.716 N/A ALA 241.A N ASN 238.A O no hydrogen 3.151 N/A LEU 242.A N LYS 239.A O no hydrogen 3.305 N/A GLU 244.A N VAL 256.A O no hydrogen 2.956 N/A LYS 246.A N THR 254.A O no hydrogen 2.884 N/A LYS 251.A NZ ASN 103.A O no hydrogen 3.262 N/A THR 254.A N LYS 246.A O no hydrogen 3.277 N/A THR 254.A OG1 LYS 246.A O no hydrogen 2.553 N/A VAL 256.A N GLU 244.A O no hydrogen 3.099 N/A LEU 258.A N LEU 242.A O no hydrogen 2.917 N/A SER 260.A OG GLU 62.A OE1 no hydrogen 2.961 N/A GLN 261.A N TYR 61.A O no hydrogen 2.947 N/A VAL 265.A N GLN 261.A O no hydrogen 3.021 N/A HIS 266.A N GLU 262.A O no hydrogen 2.889 N/A THR 267.A N GLY 263.A O no hydrogen 3.123 N/A THR 267.A OG1 GLY 263.A O no hydrogen 2.817 N/A THR 267.A OG1 ALA 264.A O no hydrogen 2.777 N/A ALA 268.A N ALA 264.A O no hydrogen 3.107 N/A LEU 269.A N VAL 265.A O no hydrogen 2.830 N/A ALA 270.A N THR 267.A O no hydrogen 3.441 N/A GLY 282.A N VAL 50.A O no hydrogen 3.307 N/A ARG 283.A N GLU 276.A O no hydrogen 3.177 N/A ARG 283.A NE LEU 284.A O no hydrogen 2.974 N/A LEU 284.A N THR 48.A O no hydrogen 2.916 N/A SER 286.A OG SER 285.A O no hydrogen 2.664 N/A LEU 289.A N LEU 25.A O no hydrogen 3.145 N/A CYS 291.A N VAL 23.A O no hydrogen 3.114 N/A ARG 292.A N ASP 189.A O no hydrogen 2.748 N/A ARG 292.A NH1 THR 19.A O no hydrogen 3.205 N/A ARG 292.A NH2 THR 19.A O no hydrogen 3.113 N/A LEU 293.A N VAL 21.A O no hydrogen 3.359 N/A LYS 294.A N GLY 187.A O no hydrogen 3.297 N/A LEU 298.A N MET 295.A O no hydrogen 3.102 N/A LYS 301.A NZ GLU 162.A OE1 no hydrogen 3.404 N/A CYS 308.A SG ALA 310.A O no hydrogen 3.264 N/A CYS 308.A SG TYR 332.A OH no hydrogen 3.072 N/A THR 313.A N GLN 331.A O no hydrogen 3.303 N/A THR 315.A N GLU 329.A O no hydrogen 3.284 N/A ALA 319.A N THR 327.A O no hydrogen 3.328 N/A THR 321.A N THR 325.A O no hydrogen 2.670 N/A THR 321.A OG1 THR 325.A O no hydrogen 2.678 N/A GLY 324.A N THR 321.A O no hydrogen 3.398 N/A VAL 326.A N LEU 378.A O no hydrogen 3.070 N/A THR 327.A N ALA 319.A O no hydrogen 3.238 N/A VAL 328.A N LEU 376.A O no hydrogen 2.927 N/A VAL 330.A N MET 374.A O no hydrogen 3.259 N/A GLN 331.A N THR 313.A O no hydrogen 2.784 N/A GLN 331.A NE2 THR 313.A OG1 no hydrogen 2.970 N/A ALA 333.A N ALA 311.A O no hydrogen 3.132 N/A CYS 339.A SG TYR 332.A OH no hydrogen 2.734 N/A LYS 340.A N SER 306.A O no hydrogen 2.780 N/A LYS 340.A NZ ASN 362.A OD1 no hydrogen 3.033 N/A VAL 341.A N PRO 363.A O no hydrogen 2.764 N/A GLN 344.A N VAL 388.A O no hydrogen 2.900 N/A ILE 359.A N GLU 377.A O no hydrogen 3.095 N/A THR 360.A N GLU 377.A O no hydrogen 3.395 N/A THR 360.A OG1 HIS 144.A ND1 no hydrogen 3.018 N/A VAL 364.A N GLY 145.A O no hydrogen 3.267 N/A ILE 365.A N CYS 339.A O no hydrogen 3.187 N/A SER 368.A OG GLY 337.A O no hydrogen 2.937 N/A SER 372.A N TYR 332.A O no hydrogen 3.127 N/A MET 374.A N VAL 330.A O no hydrogen 3.223 N/A LEU 376.A N VAL 328.A O no hydrogen 2.985 N/A GLU 377.A N THR 360.A OG1 no hydrogen 3.224 N/A LEU 378.A N VAL 326.A O no hydrogen 2.981 N/A ASP 379.A N ARG 357.A O no hydrogen 3.088 N/A ILE 387.A N HIS 398.A O no hydrogen 2.722 N/A VAL 388.A N GLN 344.A O no hydrogen 3.096 N/A ILE 389.A N ILE 396.A O no hydrogen 2.864 N/A GLY 390.A N PRO 342.A O no hydrogen 2.934 N/A ILE 396.A N ILE 389.A O no hydrogen 2.735 N/A HIS 398.A N ILE 387.A O no hydrogen 3.012 N/A TRP 400.A N SER 385.A O no hydrogen 2.739 N/A ARG 402.A NH2 SER 403.A OG no hydrogen 3.415 N/A