Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8en4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 1.A NZ GLU 240.A O no hydrogen 3.479 N/A SER 4.A OG TYR 236.A OH no hydrogen 2.660 N/A THR 9.A N GLU 12.A OE1 no hydrogen 2.929 N/A GLU 12.A N THR 9.A O no hydrogen 3.073 N/A MET 13.A N VAL 10.A O no hydrogen 3.183 N/A THR 14.A N GLU 232.A OE1 no hydrogen 2.755 N/A THR 14.A OG1 GLU 232.A OE2 no hydrogen 2.939 N/A ASN 15.A N ILE 20.A O no hydrogen 2.796 N/A ASN 15.A ND2 SER 212.A OG no hydrogen 3.050 N/A ASN 15.A ND2 LEU 225.A O no hydrogen 3.436 N/A SER 16.A OG LEU 229.A O no hydrogen 2.722 N/A ARG 17.A N ASN 15.A OD1 no hydrogen 2.985 N/A ARG 17.A NE ASP 101.A OD1 no hydrogen 3.172 N/A ARG 17.A NE ASP 101.A OD2 no hydrogen 2.969 N/A ARG 17.A NH1 ASP 226.A O no hydrogen 2.727 N/A ARG 17.A NH2 ASP 101.A O no hydrogen 3.539 N/A ARG 17.A NH2 ASP 101.A OD1 no hydrogen 3.170 N/A ARG 17.A NH2 GLN 178.A O no hydrogen 2.731 N/A ILE 20.A N PHE 18.A O no hydrogen 2.551 N/A LEU 22.A N MET 13.A O no hydrogen 2.971 N/A GLU 23.A N ARG 211.A O no hydrogen 3.016 N/A LYS 24.A N ARG 211.A O no hydrogen 3.269 N/A PHE 26.A N PHE 209.A O no hydrogen 2.875 N/A THR 27.A N HIS 281.A O no hydrogen 3.255 N/A THR 27.A OG1 LEU 207.A O no hydrogen 2.897 N/A GLN 36.A NE2 ALA 195.A O no hydrogen 2.808 N/A GLN 38.A N ASP 101.A OD2 no hydrogen 3.024 N/A GLN 38.A NE2 GLN 36.A O no hydrogen 3.197 N/A GLN 38.A NE2 ALA 195.A O no hydrogen 3.617 N/A ASN 39.A N ASP 101.A OD2 no hydrogen 3.138 N/A ASN 39.A ND2 THR 99.A O no hydrogen 2.875 N/A ARG 41.A N THR 52.A OG1 no hydrogen 2.745 N/A ARG 41.A NH1 PRO 37.A O no hydrogen 2.763 N/A ARG 41.A NH1 PRO 196.A O no hydrogen 3.132 N/A ARG 41.A NH2 PRO 196.A O no hydrogen 2.763 N/A CYS 42.A SG THR 43.A O no hydrogen 3.277 N/A CYS 42.A SG VAL 47.A O no hydrogen 3.887 N/A THR 43.A N VAL 47.A O no hydrogen 2.947 N/A THR 43.A OG1 ASP 45.A OD1 no hydrogen 2.445 N/A THR 44.A N LYS 269.A O no hydrogen 2.947 N/A THR 44.A OG1 LYS 269.A O no hydrogen 3.565 N/A GLY 46.A N THR 43.A O no hydrogen 2.981 N/A VAL 47.A N THR 43.A OG1 no hydrogen 2.970 N/A LEU 49.A N ARG 41.A O no hydrogen 2.985 N/A THR 51.A N GLN 38.A O no hydrogen 3.010 N/A THR 51.A OG1 ASN 39.A OD1 no hydrogen 2.996 N/A THR 52.A N LEU 49.A O no hydrogen 3.142 N/A THR 52.A OG1 GLN 38.A O no hydrogen 2.948 N/A THR 52.A OG1 ARG 41.A O no hydrogen 3.281 N/A THR 52.A OG1 LEU 49.A O no hydrogen 3.105 N/A GLN 53.A NE2 SER 55.A O no hydrogen 2.697 N/A SER 55.A N GLN 53.A OE1 no hydrogen 3.093 N/A CYS 60.A N GLY 98.A O no hydrogen 2.899 N/A CYS 60.A SG ARG 17.A O no hydrogen 3.729 N/A PHE 62.A N PHE 159.A O no hydrogen 3.439 N/A ARG 63.A NH1 ASN 58.A OD1 no hydrogen 3.254 N/A ARG 63.A NH2 ASN 58.A OD1 no hydrogen 3.216 N/A GLY 64.A N THR 157.A O no hydrogen 3.035 N/A ASP 65.A N ASN 78.A O no hydrogen 3.297 N/A THR 67.A N THR 76.A O no hydrogen 2.912 N/A HIS 68.A NE2 ASP 148.A O no hydrogen 2.811 N/A SER 72.A N ILE 69.A O no hydrogen 2.937 N/A ASN 74.A N SER 72.A OG no hydrogen 3.221 N/A TYR 75.A N PHE 143.A O no hydrogen 2.716 N/A THR 76.A N THR 67.A O no hydrogen 2.730 N/A MET 77.A N VAL 141.A O no hydrogen 2.725 N/A ASN 78.A N ASP 65.A O no hydrogen 2.835 N/A ASN 78.A ND2 ASP 65.A OD1 no hydrogen 2.793 N/A LEU 79.A N GLY 139.A O no hydrogen 2.841 N/A ALA 80.A N ARG 63.A O no hydrogen 2.727 N/A SER 81.A N ASN 85.A O no hydrogen 2.763 N/A SER 81.A OG ASP 86.A O no hydrogen 3.459 N/A TRP 84.A N SER 81.A O no hydrogen 3.014 N/A ASN 85.A N ASN 83.A OD1 no hydrogen 3.289 N/A TYR 87.A OH LYS 137.A O no hydrogen 2.570 N/A THR 90.A N ASP 88.A OD1 no hydrogen 3.370 N/A THR 90.A OG1 ASP 88.A OD1 no hydrogen 2.980 N/A THR 90.A OG1 ASP 88.A OD2 no hydrogen 3.160 N/A GLU 91.A N ASP 88.A O no hydrogen 3.532 N/A ILE 93.A N GLU 91.A O no hydrogen 2.727 N/A GLY 98.A N THR 51.A O no hydrogen 2.856 N/A THR 99.A N PRO 96.A O no hydrogen 2.997 N/A THR 99.A OG1 PRO 96.A O no hydrogen 2.496 N/A VAL 103.A N VAL 180.A O no hydrogen 2.869 N/A GLY 104.A N THR 129.A OG1 no hydrogen 2.767 N/A LYS 105.A NZ GLU 175.A OE1 no hydrogen 2.671 N/A LYS 105.A NZ GLU 175.A OE2 no hydrogen 3.412 N/A ILE 106.A N VAL 127.A O no hydrogen 3.016 N/A GLN 107.A N GLY 163.A O no hydrogen 2.746 N/A GLN 107.A NE2 THR 126.A OG1 no hydrogen 3.371 N/A GLY 108.A N ALA 125.A O no hydrogen 2.760 N/A VAL 109.A N THR 160.A O no hydrogen 3.130 N/A LEU 110.A N HIS 123.A O no hydrogen 2.815 N/A THR 111.A N LYS 158.A O no hydrogen 2.868 N/A THR 111.A OG1 LYS 158.A O no hydrogen 3.509 N/A GLN 112.A N ARG 121.A O no hydrogen 2.905 N/A GLN 112.A NE2 GLU 152.A O no hydrogen 2.796 N/A GLN 112.A NE2 THR 157.A OG1 no hydrogen 2.861 N/A THR 113.A N ASN 156.A O no hydrogen 3.399 N/A THR 114.A N SER 119.A O no hydrogen 2.745 N/A THR 114.A OG1 SER 119.A OG no hydrogen 3.350 N/A THR 114.A OG1 GLU 152.A OE1 no hydrogen 2.758 N/A ARG 115.A N GLN 155.A OE1 no hydrogen 3.008 N/A GLY 118.A N THR 114.A O no hydrogen 2.772 N/A SER 119.A N ASP 117.A OD1 no hydrogen 3.355 N/A SER 119.A OG ASP 117.A OD1 no hydrogen 3.351 N/A ARG 121.A N GLN 112.A O no hydrogen 3.020 N/A ARG 121.A NH1 GLN 112.A OE1 no hydrogen 3.059 N/A ARG 121.A NH1 THR 114.A OG1 no hydrogen 2.945 N/A ARG 121.A NH2 THR 114.A OG1 no hydrogen 3.129 N/A HIS 123.A N LEU 110.A O no hydrogen 2.974 N/A ALA 125.A N GLY 108.A O no hydrogen 2.984 N/A THR 126.A N GLU 144.A O no hydrogen 2.873 N/A VAL 127.A N ILE 106.A O no hydrogen 2.869 N/A TYR 128.A OH GLU 144.A OE1 no hydrogen 2.521 N/A THR 129.A N GLY 104.A O no hydrogen 3.018 N/A THR 129.A OG1 PHE 102.A O no hydrogen 2.786 N/A THR 129.A OG1 GLY 104.A O no hydrogen 2.868 N/A SER 131.A N TYR 128.A O no hydrogen 2.962 N/A SER 131.A OG TYR 128.A O no hydrogen 2.817 N/A PHE 134.A N SER 131.A O no hydrogen 3.347 N/A ALA 135.A N ARG 140.A O no hydrogen 3.085 N/A LYS 137.A N TYR 184.A O no hydrogen 2.916 N/A LYS 137.A NZ PRO 89.A O no hydrogen 2.793 N/A LYS 137.A NZ GLU 91.A O no hydrogen 2.894 N/A LYS 137.A NZ ILE 93.A O no hydrogen 3.024 N/A LEU 138.A N ALA 135.A O no hydrogen 3.155 N/A GLY 139.A N PRO 136.A O no hydrogen 2.814 N/A ARG 140.A N ALA 135.A O no hydrogen 3.031 N/A VAL 141.A N MET 77.A O no hydrogen 3.107 N/A PHE 143.A N TYR 75.A O no hydrogen 2.736 N/A GLU 144.A N THR 126.A O no hydrogen 2.902 N/A THR 145.A N ARG 73.A O no hydrogen 3.318 N/A THR 145.A OG1 ARG 73.A O no hydrogen 3.228 N/A THR 147.A N THR 145.A OG1 no hydrogen 3.283 N/A GLU 152.A N GLN 112.A OE1 no hydrogen 2.879 N/A THR 157.A N GLY 64.A O no hydrogen 2.762 N/A THR 157.A OG1 GLN 155.A O no hydrogen 3.010 N/A LYS 158.A N THR 111.A O no hydrogen 2.891 N/A PHE 159.A N PHE 62.A O no hydrogen 2.873 N/A THR 160.A N VAL 109.A O no hydrogen 3.012 N/A VAL 162.A N GLN 107.A O no hydrogen 2.906 N/A GLY 163.A N GLN 107.A O no hydrogen 3.041 N/A VAL 164.A N PRO 215.A O no hydrogen 2.990 N/A ILE 165.A N LYS 105.A O no hydrogen 3.143 N/A GLN 166.A N SER 218.A O no hydrogen 3.150 N/A GLY 169.A N ASP 167.A OD1 no hydrogen 3.461 N/A THR 170.A N ASP 167.A O no hydrogen 3.096 N/A THR 170.A OG1 GLN 166.A OE1 no hydrogen 3.557 N/A THR 170.A OG1 ASP 167.A O no hydrogen 2.575 N/A ARG 173.A N TYR 220.A O no hydrogen 2.737 N/A GLN 177.A N VAL 103.A O no hydrogen 2.906 N/A GLN 178.A NE2 ASP 226.A OD2 no hydrogen 2.899 N/A VAL 180.A N GLN 177.A O no hydrogen 3.191 N/A TYR 184.A N ASN 191.A OD1 no hydrogen 2.972 N/A GLY 186.A N SER 183.A O no hydrogen 3.441 N/A THR 189.A OG1 GLY 186.A O no hydrogen 2.980 N/A ASN 191.A ND2 PRO 182.A O no hydrogen 3.067 N/A ALA 195.A N GLN 38.A OE1 no hydrogen 2.700 N/A VAL 198.A N VAL 35.A O no hydrogen 2.829 N/A GLU 205.A N PHE 202.A O no hydrogen 3.173 N/A GLN 206.A N VAL 275.A O no hydrogen 2.829 N/A GLN 206.A NE2 THR 27.A OG1 no hydrogen 3.254 N/A GLN 206.A NE2 GLY 279.A O no hydrogen 3.009 N/A LEU 208.A N VAL 273.A O no hydrogen 2.829 N/A PHE 209.A N PHE 26.A O no hydrogen 2.597 N/A PHE 210.A N CYS 227.A O no hydrogen 3.027 N/A ARG 211.A N LYS 24.A O no hydrogen 2.921 N/A ARG 211.A NE ASP 226.A OD1 no hydrogen 2.752 N/A ARG 211.A NH2 ASP 226.A OD1 no hydrogen 3.414 N/A ARG 211.A NH2 ASP 226.A OD2 no hydrogen 3.032 N/A SER 212.A N LEU 225.A O no hydrogen 2.935 N/A SER 212.A OG PRO 21.A O no hydrogen 2.600 N/A THR 213.A N GLU 23.A OE2 no hydrogen 2.848 N/A THR 213.A OG1 GLU 23.A OE1 no hydrogen 2.536 N/A THR 213.A OG1 GLU 23.A OE2 no hydrogen 3.369 N/A MET 214.A N MET 223.A O no hydrogen 2.835 N/A CYS 217.A N VAL 164.A O no hydrogen 2.974 N/A ASN 222.A N GLU 175.A O no hydrogen 2.759 N/A ASP 224.A N ASN 222.A OD1 no hydrogen 3.356 N/A LEU 225.A N SER 212.A O no hydrogen 3.061 N/A ASP 226.A N GLN 178.A OE1 no hydrogen 2.776 N/A CYS 227.A N PHE 210.A O no hydrogen 3.108 N/A CYS 227.A SG PHE 210.A O no hydrogen 3.530 N/A CYS 227.A SG LEU 229.A O no hydrogen 3.421 N/A GLN 231.A N THR 14.A O no hydrogen 3.032 N/A GLN 231.A NE2 GLN 53.A O no hydrogen 2.935 N/A GLU 232.A N GLU 232.A OE1 no hydrogen 2.710 N/A TRP 233.A N PRO 230.A O no hydrogen 2.921 N/A VAL 234.A N PRO 230.A O no hydrogen 3.181 N/A GLN 235.A N GLN 231.A O no hydrogen 2.980 N/A GLN 235.A NE2 LEU 54.A O no hydrogen 2.858 N/A TYR 236.A N GLU 232.A O no hydrogen 2.944 N/A TYR 236.A OH SER 4.A OG no hydrogen 2.660 N/A PHE 237.A N TRP 233.A O no hydrogen 2.892 N/A TYR 238.A N VAL 234.A O no hydrogen 3.112 N/A GLN 239.A N GLN 235.A O no hydrogen 3.281 N/A GLN 239.A N TYR 236.A O no hydrogen 3.252 N/A GLN 239.A NE2 GLN 235.A O no hydrogen 3.081 N/A GLU 240.A N TYR 236.A O no hydrogen 2.968 N/A ALA 241.A N PHE 237.A O no hydrogen 3.074 N/A SER 246.A OG VAL 248.A O no hydrogen 3.203 N/A SER 246.A OG VAL 297.A O no hydrogen 2.433 N/A VAL 248.A N SER 246.A OG no hydrogen 3.166 N/A ALA 249.A N LEU 267.A O no hydrogen 2.752 N/A LEU 250.A N SER 295.A O no hydrogen 3.008 N/A LEU 251.A N CYS 265.A O no hydrogen 2.943 N/A ARG 252.A N ARG 292.A O no hydrogen 2.839 N/A ARG 252.A NE GLU 264.A OE2 no hydrogen 2.855 N/A ARG 252.A NH2 GLU 264.A OE2 no hydrogen 3.519 N/A PHE 253.A N PHE 263.A O no hydrogen 3.054 N/A VAL 254.A N TYR 290.A O no hydrogen 3.041 N/A ASN 255.A N ARG 260.A O no hydrogen 3.050 N/A ASP 257.A N ASN 255.A OD1 no hydrogen 3.177 N/A THR 258.A N ASN 255.A O no hydrogen 3.240 N/A GLY 259.A N ASN 255.A O no hydrogen 2.819 N/A ARG 260.A N THR 258.A OG1 no hydrogen 3.356 N/A LEU 262.A N PHE 253.A O no hydrogen 2.688 N/A CYS 265.A N LEU 251.A O no hydrogen 3.092 N/A LYS 266.A N THR 274.A O no hydrogen 3.012 N/A LYS 266.A NZ GLU 205.A OE2 no hydrogen 2.608 N/A LYS 266.A NZ GLN 299.A O no hydrogen 3.566 N/A LYS 266.A NZ TYR 301.A O no hydrogen 2.669 N/A LEU 267.A N ALA 249.A O no hydrogen 2.668 N/A HIS 268.A N TYR 272.A O no hydrogen 2.856 N/A HIS 268.A NE2 THR 274.A OG1 no hydrogen 2.948 N/A LYS 269.A N ASP 247.A O no hydrogen 2.994 N/A LYS 269.A NZ ASP 247.A OD1 no hydrogen 2.726 N/A GLY 271.A N HIS 268.A O no hydrogen 2.997 N/A THR 274.A N LYS 266.A O no hydrogen 3.050 N/A THR 274.A OG1 GLU 205.A OE1 no hydrogen 2.957 N/A THR 274.A OG1 HIS 268.A NE2 no hydrogen 2.948 N/A VAL 275.A N GLN 206.A O no hydrogen 2.804 N/A GLY 279.A N GLN 206.A OE1 no hydrogen 2.914 N/A HIS 281.A N THR 27.A O no hydrogen 3.046 N/A HIS 281.A ND1 ASP 282.A O no hydrogen 2.980 N/A LEU 283.A N LEU 25.A O no hydrogen 3.090 N/A ASN 288.A ND2 ASP 257.A OD1 no hydrogen 3.155 N/A ASN 288.A ND2 ASP 257.A OD2 no hydrogen 3.156 N/A GLY 289.A N PRO 286.A O no hydrogen 3.225 N/A TYR 290.A N VAL 254.A O no hydrogen 3.196 N/A ARG 292.A N ARG 252.A O no hydrogen 2.778 N/A ARG 292.A NH1 TYR 290.A OH no hydrogen 3.298 N/A ASP 294.A N LEU 250.A O no hydrogen 2.926 N/A SER 295.A OG ASP 294.A OD2 no hydrogen 2.932 N/A VAL 297.A N VAL 248.A O no hydrogen 3.350 N/A PHE 300.A N ASN 298.A OD1 no hydrogen 2.421 N/A TYR 301.A N ASN 298.A O no hydrogen 3.141 N/A MET 306.A N ALA 276.A O no hydrogen 3.026 N/A