Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8eup_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A N GLU 52.A OE1 no hydrogen 3.380 N/A GLN 6.A N SER 2.A O no hydrogen 2.930 N/A LYS 7.A N GLU 3.A O no hydrogen 3.133 N/A ALA 8.A N ASN 4.A O no hydrogen 3.314 N/A ILE 9.A N ILE 5.A O no hydrogen 3.114 N/A LYS 10.A N LYS 7.A O no hydrogen 3.275 N/A GLU 11.A N ALA 8.A O no hydrogen 3.073 N/A GLY 13.A N LYS 10.A O no hydrogen 3.022 N/A LYS 22.A N THR 18.A O no hydrogen 2.624 N/A SER 24.A N GLN 21.A O no hydrogen 3.394 N/A ILE 25.A N GLN 21.A O no hydrogen 2.918 N/A LEU 28.A N SER 24.A O no hydrogen 2.607 N/A LEU 29.A N ILE 25.A O no hydrogen 3.229 N/A ALA 30.A N PRO 27.A O no hydrogen 3.271 N/A GLY 31.A N LEU 28.A O no hydrogen 3.053 N/A SER 40.A OG LYS 37.A O no hydrogen 2.591 N/A LYS 42.A NZ ALA 36.A O no hydrogen 3.057 N/A LYS 42.A NZ LYS 37.A O no hydrogen 3.112 N/A ALA 45.A N LYS 42.A O no hydrogen 2.570 N/A PHE 46.A N LYS 42.A O no hydrogen 3.358 N/A LEU 47.A N LEU 44.A O no hydrogen 3.387 N/A ILE 48.A N LEU 44.A O no hydrogen 3.066 N/A THR 50.A OG1 PHE 46.A O no hydrogen 3.402 N/A THR 50.A OG1 LEU 47.A O no hydrogen 2.483 N/A ILE 51.A N LEU 47.A O no hydrogen 3.039 N/A GLU 52.A N ILE 48.A O no hydrogen 3.203 N/A MET 53.A N PRO 49.A O no hydrogen 2.805 N/A LEU 54.A N THR 50.A O no hydrogen 2.888 N/A TYR 55.A N ILE 51.A O no hydrogen 3.090 N/A ALA 56.A N GLU 52.A O no hydrogen 2.894 N/A LEU 57.A N MET 53.A O no hydrogen 3.245 N/A LYS 58.A N TYR 55.A O no hydrogen 3.156 N/A PHE 59.A N LEU 54.A O no hydrogen 3.115 N/A ASN 63.A N LYS 60.A O no hydrogen 3.153 N/A THR 65.A N VAL 136.A O no hydrogen 3.246 N/A THR 65.A OG1 ASN 116.A O no hydrogen 2.906 N/A GLY 66.A N ASN 116.A O no hydrogen 3.070 N/A VAL 67.A N ASN 116.A O no hydrogen 3.482 N/A ILE 68.A N SER 142.A O no hydrogen 3.015 N/A ILE 69.A N LEU 118.A O no hydrogen 2.866 N/A ILE 70.A N VAL 144.A O no hydrogen 2.896 N/A SER 71.A N ALA 120.A O no hydrogen 3.037 N/A SER 71.A OG THR 73.A O no hydrogen 2.641 N/A THR 73.A N SER 71.A OG no hydrogen 3.323 N/A ALA 77.A N THR 73.A O no hydrogen 3.341 N/A LEU 78.A N ARG 74.A O no hydrogen 3.018 N/A GLN 79.A N GLU 75.A O no hydrogen 3.068 N/A GLN 79.A NE2 VAL 270.A O no hydrogen 3.293 N/A ILE 80.A N LEU 76.A O no hydrogen 3.074 N/A PHE 81.A N ALA 77.A O no hydrogen 3.062 N/A GLY 82.A N LEU 78.A O no hydrogen 2.843 N/A VAL 83.A N GLN 79.A O no hydrogen 3.170 N/A ALA 84.A N ILE 80.A O no hydrogen 2.822 N/A LYS 85.A N PHE 81.A O no hydrogen 2.919 N/A GLU 86.A N VAL 83.A O no hydrogen 3.182 N/A LEU 87.A N VAL 83.A O no hydrogen 3.112 N/A LEU 88.A N ALA 84.A O no hydrogen 2.982 N/A HIS 91.A N LEU 88.A O no hydrogen 3.251 N/A GLN 93.A NE2 PHE 59.A O no hydrogen 3.553 N/A THR 94.A N ASN 116.A OD1 no hydrogen 3.474 N/A THR 94.A OG1 ASN 116.A OD1 no hydrogen 2.722 N/A GLY 96.A N LEU 117.A O no hydrogen 2.926 N/A VAL 98.A N VAL 119.A O no hydrogen 3.334 N/A ILE 99.A N GLU 107.A OE2 no hydrogen 2.449 N/A ARG 104.A NE ASP 127.A OD2 no hydrogen 2.802 N/A ARG 104.A NH2 ASP 127.A OD2 no hydrogen 2.574 N/A ALA 106.A N ASN 103.A O no hydrogen 2.718 N/A ALA 106.A N ASN 103.A OD1 no hydrogen 3.233 N/A GLU 107.A N ASN 103.A O no hydrogen 2.478 N/A LYS 110.A NZ GLU 107.A O no hydrogen 2.759 N/A VAL 112.A N ALA 108.A O no hydrogen 2.937 N/A LYS 113.A N ASP 109.A O no hydrogen 3.400 N/A LYS 113.A NZ ASP 109.A OD1 no hydrogen 3.216 N/A GLY 114.A N LEU 111.A O no hydrogen 3.138 N/A ASN 116.A N THR 94.A OG1 no hydrogen 2.811 N/A ASN 116.A ND2 LYS 60.A O no hydrogen 2.368 N/A ASN 116.A ND2 GLY 64.A O no hydrogen 2.412 N/A LEU 117.A N THR 94.A O no hydrogen 2.939 N/A LEU 118.A N VAL 67.A O no hydrogen 3.157 N/A VAL 119.A N GLY 96.A O no hydrogen 3.242 N/A ALA 120.A N ILE 69.A O no hydrogen 2.788 N/A THR 121.A N VAL 98.A O no hydrogen 3.410 N/A ARG 124.A NH1 ALA 102.A O no hydrogen 3.524 N/A ARG 124.A NH1 GLU 107.A OE1 no hydrogen 2.571 N/A LEU 125.A N THR 121.A O no hydrogen 2.797 N/A LEU 126.A N PRO 122.A O no hydrogen 3.091 N/A ASP 127.A N GLY 123.A O no hydrogen 3.445 N/A HIS 128.A N ARG 124.A O no hydrogen 3.127 N/A HIS 128.A ND1 THR 132.A OG1 no hydrogen 2.897 N/A LEU 129.A N LEU 125.A O no hydrogen 2.903 N/A GLN 130.A N ASP 127.A O no hydrogen 3.434 N/A ASN 131.A N ASP 127.A O no hydrogen 2.863 N/A ASN 131.A ND2 ASP 127.A OD1 no hydrogen 2.350 N/A THR 132.A N HIS 128.A O no hydrogen 3.278 N/A THR 132.A OG1 HIS 128.A ND1 no hydrogen 2.897 N/A ARG 141.A N GLY 66.A O no hydrogen 2.477 N/A ARG 141.A NH1 ASN 171.A O no hydrogen 3.410 N/A SER 142.A N GLY 66.A O no hydrogen 2.686 N/A LEU 143.A N GLN 173.A O no hydrogen 3.351 N/A VAL 144.A N ILE 68.A O no hydrogen 2.925 N/A ILE 145.A N LEU 175.A O no hydrogen 2.670 N/A ALA 148.A N PHE 177.A O no hydrogen 2.884 N/A ARG 150.A N ASP 149.A OD1 no hydrogen 2.838 N/A ARG 150.A NH2 ASP 290.A O no hydrogen 2.719 N/A ILE 151.A N GLU 147.A O no hydrogen 2.859 N/A LEU 152.A N ALA 148.A O no hydrogen 2.759 N/A GLU 153.A N ASP 149.A O no hydrogen 2.892 N/A ILE 154.A N ARG 150.A O no hydrogen 3.036 N/A MET 160.A N PHE 156.A O no hydrogen 3.068 N/A ARG 161.A N GLU 157.A O no hydrogen 3.327 N/A GLN 162.A N ASP 158.A O no hydrogen 3.027 N/A ILE 163.A N GLU 159.A O no hydrogen 2.691 N/A MET 164.A N MET 160.A O no hydrogen 2.906 N/A LYS 165.A NZ GLN 162.A OE1 no hydrogen 3.413 N/A ILE 166.A N ILE 163.A O no hydrogen 2.816 N/A LEU 167.A N ILE 163.A O no hydrogen 3.213 N/A GLU 170.A N GLU 170.A OE1 no hydrogen 2.644 N/A ARG 172.A NE THR 174.A OG1 no hydrogen 3.239 N/A ARG 172.A NH2 THR 174.A OG1 no hydrogen 2.783 N/A GLN 173.A N GLN 173.A OE1 no hydrogen 2.574 N/A LEU 175.A N LEU 143.A O no hydrogen 2.912 N/A LEU 176.A N VAL 34.A O no hydrogen 3.466 N/A PHE 177.A N ILE 145.A O no hydrogen 2.752 N/A LEU 182.A N LYS 178.A O no hydrogen 3.144 N/A ALA 183.A N VAL 179.A O no hydrogen 2.888 N/A ARG 184.A N GLU 180.A O no hydrogen 2.586 N/A ILE 185.A N LEU 182.A O no hydrogen 3.170 N/A SER 186.A N ALA 183.A O no hydrogen 2.904 N/A GLU 187.A N SER 324.A OG no hydrogen 2.823 N/A GLN 188.A NE2 GLY 189.A O no hydrogen 2.880 N/A GLY 189.A N SER 303.A O no hydrogen 3.328 N/A TYR 190.A N ASN 326.A O no hydrogen 3.072 N/A VAL 191.A N MET 305.A O no hydrogen 2.876 N/A VAL 193.A N LEU 307.A O no hydrogen 3.118 N/A SER 195.A N ASP 194.A OD1 no hydrogen 2.707 N/A LYS 197.A N ASP 196.A OD1 no hydrogen 2.521 N/A ARG 198.A N SER 195.A O no hydrogen 3.171 N/A ARG 198.A NH1 TYR 286.A O no hydrogen 3.035 N/A ARG 198.A NH1 ASP 287.A OD1 no hydrogen 3.133 N/A LEU 201.A N LYS 197.A O no hydrogen 2.794 N/A LEU 202.A N ARG 198.A O no hydrogen 3.207 N/A PHE 203.A N PHE 199.A O no hydrogen 3.091 N/A SER 204.A N LEU 200.A O no hydrogen 3.098 N/A SER 204.A OG LEU 200.A O no hydrogen 3.224 N/A SER 204.A OG LEU 201.A O no hydrogen 2.460 N/A PHE 205.A N LEU 201.A O no hydrogen 2.831 N/A LEU 206.A N LEU 202.A O no hydrogen 2.876 N/A LYS 207.A N PHE 203.A O no hydrogen 3.002 N/A ARG 208.A N SER 204.A O no hydrogen 2.961 N/A ASN 209.A N PHE 205.A O no hydrogen 3.146 N/A ASN 209.A ND2 PHE 205.A O no hydrogen 3.434 N/A LYS 212.A N ASN 209.A O no hydrogen 3.177 N/A LYS 213.A NZ PHE 257.A O no hydrogen 2.702 N/A LYS 213.A NZ ALA 260.A O no hydrogen 2.596 N/A VAL 214.A N GLY 263.A O no hydrogen 2.958 N/A ILE 215.A N TRP 282.A O no hydrogen 2.819 N/A VAL 216.A N LEU 265.A O no hydrogen 3.073 N/A PHE 217.A N VAL 284.A O no hydrogen 2.639 N/A MET 218.A N CYS 267.A O no hydrogen 3.357 N/A SER 219.A N ASP 287.A OD2 no hydrogen 2.423 N/A SER 219.A OG PRO 288.A O no hydrogen 3.073 N/A SER 219.A OG TYR 370.A OH no hydrogen 3.254 N/A SER 220.A OG SER 362.A OG no hydrogen 2.743 N/A CYS 221.A SG HIS 242.A ND1 no hydrogen 2.904 N/A CYS 221.A SG GLN 245.A OE1 no hydrogen 3.274 N/A SER 223.A N SER 220.A OG no hydrogen 2.895 N/A VAL 224.A N SER 220.A O no hydrogen 3.052 N/A LYS 225.A N CYS 221.A O no hydrogen 3.099 N/A TYR 226.A N ALA 222.A O no hydrogen 3.025 N/A TYR 226.A OH PHE 390.A O no hydrogen 2.317 N/A MET 227.A N SER 223.A O no hydrogen 2.883 N/A ALA 228.A N VAL 224.A O no hydrogen 3.198 N/A GLU 229.A N LYS 225.A O no hydrogen 2.978 N/A LEU 230.A N TYR 226.A O no hydrogen 2.729 N/A LEU 231.A N MET 227.A O no hydrogen 2.737 N/A ASN 232.A N ALA 228.A O no hydrogen 3.077 N/A ASN 232.A ND2 VAL 238.A O no hydrogen 3.310 N/A TYR 233.A N GLU 229.A O no hydrogen 3.084 N/A TYR 233.A N LEU 230.A O no hydrogen 3.055 N/A ILE 234.A N LEU 231.A O no hydrogen 3.073 N/A LEU 236.A N LEU 231.A O no hydrogen 2.825 N/A VAL 238.A N ASN 232.A OD1 no hydrogen 2.506 N/A LEU 239.A N ILE 264.A O no hydrogen 3.048 N/A LEU 241.A N LEU 266.A O no hydrogen 2.914 N/A HIS 242.A N ASP 240.A OD1 no hydrogen 2.846 N/A GLY 243.A N ASP 240.A OD1 no hydrogen 3.012 N/A GLN 245.A N HIS 242.A O no hydrogen 2.825 N/A ARG 250.A N LYS 246.A O no hydrogen 3.048 N/A THR 251.A N GLN 247.A O no hydrogen 2.952 N/A THR 251.A OG1 GLN 247.A O no hydrogen 3.203 N/A THR 251.A OG1 GLN 248.A O no hydrogen 2.536 N/A ASN 252.A N GLN 248.A O no hydrogen 2.867 N/A THR 253.A N ARG 249.A O no hydrogen 2.731 N/A THR 253.A OG1 ARG 249.A O no hydrogen 2.435 N/A PHE 254.A N ARG 250.A O no hydrogen 2.832 N/A PHE 255.A N THR 251.A O no hydrogen 2.788 N/A GLU 256.A N ASN 252.A O no hydrogen 2.801 N/A PHE 257.A N THR 253.A O no hydrogen 3.019 N/A CYS 258.A N PHE 254.A O no hydrogen 3.169 N/A CYS 258.A N PHE 255.A O no hydrogen 2.985 N/A CYS 258.A SG PHE 254.A O no hydrogen 3.234 N/A ASN 259.A N PHE 255.A O no hydrogen 3.446 N/A ALA 260.A N GLU 256.A O no hydrogen 3.144 N/A GLU 261.A N GLU 261.A OE1 no hydrogen 2.735 N/A LYS 262.A NZ LEU 210.A O no hydrogen 2.954 N/A LEU 265.A N VAL 214.A O no hydrogen 3.151 N/A LEU 266.A N LEU 239.A O no hydrogen 3.064 N/A CYS 267.A N VAL 216.A O no hydrogen 3.336 N/A CYS 267.A SG THR 268.A O no hydrogen 3.206 N/A ALA 271.A N THR 268.A OG1 no hydrogen 2.850 N/A ALA 272.A N THR 268.A O no hydrogen 3.146 N/A ARG 273.A N VAL 270.A O no hydrogen 3.310 N/A LEU 275.A N ALA 272.A O no hydrogen 3.175 N/A TRP 282.A N LYS 213.A O no hydrogen 2.794 N/A ILE 283.A N LYS 302.A O no hydrogen 3.299 N/A VAL 284.A N ILE 215.A O no hydrogen 2.847 N/A GLN 285.A N LEU 304.A O no hydrogen 3.302 N/A GLN 285.A NE2 ASN 269.A OD1 no hydrogen 2.378 N/A GLN 285.A NE2 ASP 287.A O no hydrogen 3.628 N/A TYR 286.A N PHE 217.A O no hydrogen 2.365 N/A ASP 294.A N ASP 291.A O no hydrogen 2.937 N/A TYR 295.A N ASP 291.A O no hydrogen 2.870 N/A ILE 296.A N PRO 292.A O no hydrogen 3.197 N/A ARG 298.A N ASP 294.A O no hydrogen 2.747 N/A VAL 299.A N TYR 295.A O no hydrogen 3.326 N/A GLY 300.A N ILE 296.A O no hydrogen 3.372 N/A LYS 302.A N ASP 281.A O no hydrogen 3.299 N/A LEU 304.A N ILE 283.A O no hydrogen 3.076 N/A PHE 306.A N GLN 285.A O no hydrogen 3.436 N/A LEU 307.A N VAL 191.A O no hydrogen 3.487 N/A GLU 311.A N ALA 308.A O no hydrogen 3.292 N/A PHE 314.A N GLU 311.A O no hydrogen 3.512 N/A LEU 315.A N LEU 312.A O no hydrogen 2.985 N/A TYR 317.A N GLY 313.A O no hydrogen 2.868 N/A LEU 318.A N PHE 314.A O no hydrogen 2.973 N/A LYS 319.A N LEU 315.A O no hydrogen 3.346 N/A THR 320.A N ARG 316.A O no hydrogen 3.207 N/A THR 320.A OG1 TYR 317.A O no hydrogen 2.506 N/A ALA 321.A N LEU 318.A O no hydrogen 3.037 N/A LYS 322.A N LYS 319.A O no hydrogen 3.242 N/A LYS 322.A NZ THR 320.A O no hydrogen 2.314 N/A VAL 323.A N LEU 318.A O no hydrogen 3.270 N/A ASN 326.A N GLN 188.A O no hydrogen 2.970 N/A PHE 328.A N TYR 190.A O no hydrogen 3.119 N/A VAL 335.A N ALA 332.A O no hydrogen 3.269 N/A GLN 341.A N VAL 338.A O no hydrogen 2.995 N/A LEU 342.A N VAL 338.A O no hydrogen 2.866 N/A LEU 342.A N GLN 339.A O no hydrogen 3.208 N/A GLU 343.A N GLN 339.A O no hydrogen 3.426 N/A LYS 344.A N GLU 343.A OE1 no hydrogen 2.657 N/A LYS 344.A NZ LYS 344.A O no hydrogen 3.157 N/A LEU 345.A N GLN 341.A O no hydrogen 3.154 N/A VAL 346.A N LEU 342.A O no hydrogen 3.091 N/A SER 347.A N GLU 343.A O no hydrogen 3.030 N/A SER 347.A OG GLU 343.A O no hydrogen 3.548 N/A LYS 348.A N LYS 344.A O no hydrogen 3.071 N/A ASN 349.A N LEU 345.A O no hydrogen 2.863 N/A GLN 354.A N TYR 350.A O no hydrogen 2.917 N/A SER 355.A N TYR 351.A O no hydrogen 2.980 N/A SER 355.A OG GLU 229.A OE1 no hydrogen 3.382 N/A SER 355.A OG TYR 351.A O no hydrogen 3.380 N/A ALA 356.A N LEU 352.A O no hydrogen 3.097 N/A LYS 357.A N GLN 353.A O no hydrogen 3.088 N/A ASP 358.A N GLN 354.A O no hydrogen 3.124 N/A GLY 359.A N SER 355.A O no hydrogen 2.805 N/A TYR 360.A N ALA 356.A O no hydrogen 2.525 N/A ARG 361.A N LYS 357.A O no hydrogen 2.617 N/A SER 362.A N ASP 358.A O no hydrogen 2.892 N/A SER 362.A OG SER 220.A OG no hydrogen 2.743 N/A TYR 363.A N GLY 359.A O no hydrogen 2.813 N/A LEU 364.A N TYR 360.A O no hydrogen 3.029 N/A GLN 365.A N ARG 361.A O no hydrogen 2.963 N/A GLN 365.A NE2 GLY 101.A O no hydrogen 2.463 N/A ALA 366.A N SER 362.A O no hydrogen 2.951 N/A TYR 367.A N TYR 363.A O no hydrogen 2.963 N/A TYR 367.A OH GLU 311.A OE2 no hydrogen 2.268 N/A ALA 368.A N LEU 364.A O no hydrogen 2.786 N/A SER 369.A N ALA 366.A O no hydrogen 3.041 N/A SER 369.A OG ALA 366.A O no hydrogen 2.733 N/A TYR 370.A N TYR 367.A O no hydrogen 3.250 N/A TYR 370.A OH SER 219.A OG no hydrogen 3.254 N/A LYS 373.A N SER 371.A O no hydrogen 2.821 N/A LYS 373.A NZ TYR 367.A O no hydrogen 3.329 N/A LYS 373.A NZ PHE 376.A O no hydrogen 3.421 N/A ILE 375.A N LEU 372.A O no hydrogen 3.118 N/A PHE 376.A N LEU 372.A O no hydrogen 2.775 N/A ASN 379.A N ASP 377.A OD1 no hydrogen 3.367 N/A LEU 381.A N ASP 377.A O no hydrogen 3.381 N/A VAL 386.A N ASP 382.A O no hydrogen 3.289 N/A ALA 387.A N LEU 383.A O no hydrogen 2.935 N/A LYS 388.A N ALA 384.A O no hydrogen 3.126 N/A SER 389.A N LYS 385.A O no hydrogen 3.281 N/A SER 389.A OG VAL 386.A O no hydrogen 2.688 N/A PHE 390.A N VAL 386.A O no hydrogen 3.351 N/A GLY 391.A N LYS 388.A O no hydrogen 3.197 N/A PHE 392.A N ALA 387.A O no hydrogen 2.958 N/A