Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8ffx_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A OG1 ILE 1.A O no hydrogen 3.314 N/A LYS 9.A N ARG 79.A O no hydrogen 2.950 N/A LYS 9.A NZ THR 80.A O no hydrogen 2.737 N/A GLY 14.A N ASP 13.A OD1 no hydrogen 2.777 N/A VAL 17.A N ASN 53.A O no hydrogen 2.874 N/A GLN 19.A NE2 TRP 20.A O no hydrogen 2.913 N/A GLN 19.A NE2 VAL 56.A O no hydrogen 2.921 N/A LYS 26.A NZ GLU 392.A OE1 no hydrogen 3.226 N/A LYS 26.A NZ GLU 392.A OE2 no hydrogen 2.464 N/A ILE 27.A N THR 23.A O no hydrogen 3.022 N/A LYS 28.A N GLU 24.A O no hydrogen 3.043 N/A ALA 29.A N GLU 25.A O no hydrogen 3.091 N/A LEU 30.A N LYS 26.A O no hydrogen 2.932 N/A VAL 31.A N ILE 27.A O no hydrogen 2.833 N/A GLU 32.A N LYS 28.A O no hydrogen 2.933 N/A ILE 33.A N ALA 29.A O no hydrogen 2.840 N/A CYS 34.A N LEU 30.A O no hydrogen 2.813 N/A THR 35.A N VAL 31.A O no hydrogen 2.852 N/A THR 35.A OG1 VAL 31.A O no hydrogen 2.955 N/A GLU 36.A N GLU 32.A O no hydrogen 3.142 N/A MET 37.A N ILE 33.A O no hydrogen 2.941 N/A GLU 38.A N CYS 34.A O no hydrogen 2.816 N/A LYS 39.A N THR 35.A O no hydrogen 3.258 N/A GLU 40.A N GLU 36.A O no hydrogen 3.037 N/A GLY 41.A N GLU 38.A O no hydrogen 3.208 N/A LYS 42.A N MET 37.A O no hydrogen 2.893 N/A LYS 42.A NZ GLU 40.A OE1 no hydrogen 2.487 N/A SER 44.A N GLN 141.A O no hydrogen 3.047 N/A LYS 45.A NZ GLU 38.A OE2 no hydrogen 2.858 N/A LYS 45.A NZ TYR 140.A OH no hydrogen 3.411 N/A ILE 46.A N ARG 139.A O no hydrogen 3.346 N/A GLU 49.A N GLU 49.A OE1 no hydrogen 2.612 N/A ASN 50.A N GLY 47.A O no hydrogen 3.260 N/A ASN 50.A ND2 LYS 122.A O no hydrogen 3.085 N/A ASN 50.A ND2 GLN 141.A OE1 no hydrogen 3.419 N/A TYR 52.A N ASN 50.A OD1 no hydrogen 3.061 N/A TYR 52.A OH ASP 13.A OD1 no hydrogen 2.946 N/A ASN 53.A N PRO 15.A O no hydrogen 2.858 N/A ASN 53.A ND2 VAL 17.A O no hydrogen 2.682 N/A VAL 56.A N GLN 19.A OE1 no hydrogen 2.815 N/A PHE 57.A N LEU 70.A O no hydrogen 2.896 N/A ILE 59.A N ARG 68.A O no hydrogen 2.710 N/A LYS 61.A NZ ASP 106.A OD2 no hydrogen 3.465 N/A SER 64.A N LYS 61.A O no hydrogen 2.912 N/A LYS 66.A N SER 64.A OG no hydrogen 3.212 N/A ARG 68.A N ILE 59.A O no hydrogen 2.579 N/A ARG 68.A NH2 ASP 106.A OD1 no hydrogen 3.452 N/A ARG 68.A NH2 ASP 106.A OD2 no hydrogen 3.248 N/A LYS 69.A NZ TYR 142.A OH no hydrogen 2.659 N/A LEU 70.A N PHE 57.A O no hydrogen 2.843 N/A ASP 72.A N PRO 55.A O no hydrogen 2.948 N/A ARG 74.A N ASP 72.A OD1 no hydrogen 3.230 N/A ARG 74.A NE ASP 72.A OD1 no hydrogen 2.887 N/A ARG 74.A NH1 PRO 400.A O no hydrogen 3.069 N/A ARG 74.A NH2 ASP 72.A OD2 no hydrogen 3.118 N/A ASN 77.A N PHE 73.A O no hydrogen 2.721 N/A ASN 77.A ND2 GLY 148.A O no hydrogen 3.170 N/A LYS 78.A N ARG 74.A O no hydrogen 3.284 N/A LYS 78.A NZ GLU 75.A OE1 no hydrogen 3.510 N/A ARG 79.A N LEU 76.A O no hydrogen 2.844 N/A ARG 79.A NE GLU 75.A OE2 no hydrogen 2.597 N/A ARG 79.A NH1 ASP 13.A O no hydrogen 2.954 N/A ARG 79.A NH2 GLU 75.A OE2 no hydrogen 2.649 N/A THR 80.A N LEU 76.A O no hydrogen 3.117 N/A THR 80.A OG1 GLN 81.A O no hydrogen 3.463 N/A TRP 84.A N ASP 82.A O no hydrogen 3.032 N/A GLU 85.A N GLU 85.A OE1 no hydrogen 2.781 N/A HIS 92.A NE2 VAL 369.A O no hydrogen 2.454 N/A LEU 96.A N PRO 93.A O no hydrogen 3.013 N/A LYS 98.A N GLY 95.A O no hydrogen 3.280 N/A LYS 99.A NZ ASP 173.A O no hydrogen 3.323 N/A LYS 99.A NZ ASP 188.A OD2 no hydrogen 3.541 N/A LYS 100.A N ASP 188.A OD1 no hydrogen 3.413 N/A SER 101.A OG SER 187.A O no hydrogen 2.306 N/A SER 101.A OG SER 187.A OG no hydrogen 2.812 N/A VAL 102.A N LEU 222.A O no hydrogen 3.048 N/A THR 103.A N VAL 185.A O no hydrogen 2.586 N/A VAL 104.A N TYR 220.A O no hydrogen 3.307 N/A LEU 105.A N LEU 183.A O no hydrogen 2.788 N/A VAL 107.A N ASP 181.A O no hydrogen 3.146 N/A GLY 108.A N ASP 106.A OD1 no hydrogen 3.182 N/A ALA 110.A N VAL 107.A O no hydrogen 3.134 N/A TYR 111.A N GLY 108.A O no hydrogen 2.953 N/A TYR 111.A OH MET 180.A O no hydrogen 2.440 N/A PHE 112.A N ASP 109.A O no hydrogen 3.180 N/A SER 113.A OG ALA 110.A O no hydrogen 3.169 N/A VAL 114.A N TYR 111.A O no hydrogen 3.314 N/A LEU 116.A N ASN 143.A O no hydrogen 2.808 N/A ASP 119.A N ASP 117.A OD1 no hydrogen 2.566 N/A PHE 120.A N ASP 117.A O no hydrogen 2.952 N/A PHE 120.A N ASP 117.A OD1 no hydrogen 3.052 N/A ARG 121.A NE LEU 116.A O no hydrogen 3.004 N/A ARG 121.A NH1 ASN 143.A OD1 no hydrogen 3.126 N/A ARG 121.A NH2 LEU 116.A O no hydrogen 2.667 N/A LYS 122.A NZ ASP 119.A O no hydrogen 3.556 N/A TYR 123.A N PHE 120.A O no hydrogen 3.020 N/A THR 124.A N ARG 121.A O no hydrogen 2.980 N/A THR 124.A OG1 ARG 121.A O no hydrogen 2.993 N/A PHE 126.A N TYR 140.A O no hydrogen 3.013 N/A THR 127.A OG1 ASN 53.A OD1 no hydrogen 2.360 N/A ILE 128.A N ILE 138.A O no hydrogen 2.746 N/A SER 130.A OG THR 135.A O no hydrogen 2.585 N/A GLU 134.A N ILE 131.A O no hydrogen 3.068 N/A THR 135.A N SER 130.A OG no hydrogen 3.333 N/A ILE 138.A N ILE 128.A O no hydrogen 3.047 N/A ARG 139.A NH1 ASN 50.A O no hydrogen 2.557 N/A ARG 139.A NH2 TYR 52.A O no hydrogen 2.209 N/A ARG 139.A NH2 ASN 53.A OD1 no hydrogen 3.412 N/A TYR 140.A N PHE 126.A O no hydrogen 3.071 N/A GLN 141.A N SER 44.A O no hydrogen 2.922 N/A TYR 142.A N THR 124.A OG1 no hydrogen 2.930 N/A ASN 143.A N LYS 42.A O no hydrogen 2.815 N/A ASN 143.A ND2 GLY 41.A O no hydrogen 3.259 N/A ASN 143.A ND2 SER 44.A OG no hydrogen 2.573 N/A LEU 145.A N VAL 114.A O no hydrogen 3.091 N/A GLY 148.A N ASP 181.A OD1 no hydrogen 3.231 N/A LYS 150.A N ASN 77.A OD1 no hydrogen 2.739 N/A LYS 150.A NZ ASN 77.A O no hydrogen 3.205 N/A LYS 150.A NZ THR 80.A O no hydrogen 3.070 N/A LYS 150.A NZ ASP 82.A OD1 no hydrogen 2.853 N/A SER 152.A N TRP 149.A O no hydrogen 3.153 N/A SER 152.A OG PRO 146.A O no hydrogen 2.557 N/A SER 152.A OG TRP 149.A O no hydrogen 3.566 N/A ILE 155.A N GLY 151.A O no hydrogen 2.868 N/A PHE 156.A N SER 152.A O no hydrogen 3.001 N/A GLN 157.A NE2 GLN 87.A OE1 no hydrogen 3.273 N/A SER 158.A OG ILE 155.A O no hydrogen 3.374 N/A MET 160.A N PHE 156.A O no hydrogen 2.684 N/A THR 161.A N GLN 157.A O no hydrogen 3.379 N/A THR 161.A OG1 SER 158.A O no hydrogen 3.279 N/A LYS 162.A N SER 159.A O no hydrogen 3.054 N/A ILE 163.A N SER 159.A O no hydrogen 3.326 N/A GLU 165.A N LYS 162.A O no hydrogen 3.416 N/A LYS 168.A N LEU 164.A O no hydrogen 2.808 N/A LYS 169.A N GLU 165.A O no hydrogen 2.996 N/A GLN 170.A N PRO 166.A O no hydrogen 2.875 N/A ASN 171.A N PHE 167.A O no hydrogen 3.061 N/A ILE 174.A N ASN 171.A O no hydrogen 3.395 N/A TYR 177.A N TYR 184.A O no hydrogen 3.005 N/A TYR 179.A N ASP 182.A O no hydrogen 3.085 N/A ASP 182.A N TYR 179.A O no hydrogen 2.844 N/A LEU 183.A N LEU 105.A O no hydrogen 2.782 N/A TYR 184.A N TYR 177.A O no hydrogen 2.649 N/A VAL 185.A N THR 103.A O no hydrogen 2.727 N/A SER 187.A N SER 101.A O no hydrogen 2.828 N/A SER 187.A OG SER 101.A OG no hydrogen 2.812 N/A SER 187.A OG HIS 194.A ND1 no hydrogen 2.500 N/A GLN 193.A NE2 GLU 190.A OE1 no hydrogen 2.881 N/A HIS 194.A N GLU 190.A O no hydrogen 2.803 N/A HIS 194.A ND1 SER 187.A OG no hydrogen 2.500 N/A ARG 195.A N ILE 191.A O no hydrogen 3.207 N/A ARG 195.A NH1 GLU 221.A OE1 no hydrogen 3.311 N/A THR 196.A OG1 GLN 193.A O no hydrogen 2.651 N/A LYS 197.A N GLN 193.A O no hydrogen 3.117 N/A ILE 198.A N HIS 194.A O no hydrogen 2.913 N/A GLU 199.A N ARG 195.A O no hydrogen 3.239 N/A GLU 200.A N THR 196.A O no hydrogen 3.088 N/A LEU 201.A N LYS 197.A O no hydrogen 3.368 N/A ARG 202.A N ILE 198.A O no hydrogen 2.788 N/A GLN 203.A N GLU 199.A O no hydrogen 2.940 N/A HIS 204.A N LEU 201.A O no hydrogen 3.311 N/A HIS 204.A ND1 GLU 200.A O no hydrogen 3.120 N/A ARG 207.A N GLN 203.A O no hydrogen 3.377 N/A TRP 208.A N HIS 204.A O no hydrogen 3.280 N/A GLY 209.A N LEU 205.A O no hydrogen 2.548 N/A LEU 210.A N LEU 206.A O no hydrogen 2.983 N/A THR 211.A OG1 ARG 207.A O no hydrogen 3.032 N/A THR 211.A OG1 TRP 208.A O no hydrogen 3.469 N/A LEU 222.A N VAL 102.A O no hydrogen 2.741 N/A HIS 223.A ND1 LYS 100.A O no hydrogen 3.015 N/A LYS 226.A N HIS 223.A O no hydrogen 2.852 N/A GLN 230.A N THR 339.A OG1 no hydrogen 3.219 N/A LYS 237.A NZ ASP 244.A OD2 no hydrogen 3.351 N/A THR 241.A N ASP 244.A OD2 no hydrogen 3.238 N/A VAL 242.A N GLU 279.A O no hydrogen 2.930 N/A ASN 243.A N LEU 277.A O no hydrogen 2.867 N/A ASP 244.A N THR 241.A OG1 no hydrogen 3.026 N/A ILE 245.A N THR 241.A O no hydrogen 2.918 N/A GLN 246.A N VAL 242.A O no hydrogen 2.892 N/A LYS 247.A N ASN 243.A O no hydrogen 2.997 N/A LEU 248.A N ASP 244.A O no hydrogen 3.033 N/A VAL 249.A N ILE 245.A O no hydrogen 2.863 N/A GLY 250.A N GLN 246.A O no hydrogen 2.908 N/A LYS 251.A N LYS 247.A O no hydrogen 2.798 N/A LYS 251.A NZ VAL 233.A O no hydrogen 2.923 N/A LYS 251.A NZ TRP 414.A O no hydrogen 3.510 N/A LEU 252.A N LEU 248.A O no hydrogen 2.784 N/A ASN 253.A N VAL 249.A O no hydrogen 2.803 N/A TRP 254.A N GLY 250.A O no hydrogen 2.962 N/A ALA 255.A N LYS 251.A O no hydrogen 2.859 N/A SER 256.A N LEU 252.A O no hydrogen 2.900 N/A SER 256.A N ASN 253.A O no hydrogen 3.313 N/A SER 256.A OG ASN 253.A O no hydrogen 2.553 N/A GLN 257.A N TRP 254.A O no hydrogen 3.194 N/A GLN 257.A NE2 TRP 254.A O no hydrogen 3.337 N/A ILE 258.A N ALA 255.A O no hydrogen 2.900 N/A TYR 259.A N ALA 255.A O no hydrogen 2.824 N/A TYR 259.A OH GLU 300.A O no hydrogen 3.176 N/A LYS 263.A N ASN 294.A OD1 no hydrogen 3.055 N/A GLN 266.A N GLU 290.A OE2 no hydrogen 2.927 N/A LEU 267.A N GLU 290.A OE1 no hydrogen 3.156 N/A SER 268.A N VAL 264.A O no hydrogen 3.031 N/A SER 268.A OG VAL 264.A O no hydrogen 3.099 N/A LYS 269.A N ARG 265.A O no hydrogen 3.163 N/A LEU 270.A N LEU 267.A O no hydrogen 3.002 N/A LEU 271.A N SER 268.A O no hydrogen 3.011 N/A GLU 279.A N ALA 276.A O no hydrogen 3.089 N/A ILE 281.A N TRP 240.A O no hydrogen 2.684 N/A ALA 287.A N THR 284.A OG1 no hydrogen 3.361 N/A GLU 288.A N THR 284.A O no hydrogen 2.768 N/A LEU 289.A N GLU 285.A O no hydrogen 2.854 N/A GLU 290.A N GLU 286.A O no hydrogen 3.213 N/A LEU 291.A N ALA 287.A O no hydrogen 2.882 N/A ALA 292.A N GLU 288.A O no hydrogen 3.257 N/A ALA 292.A N LEU 289.A O no hydrogen 2.685 N/A GLU 293.A N LEU 289.A O no hydrogen 3.297 N/A GLU 293.A N GLU 293.A OE1 no hydrogen 3.151 N/A ASN 294.A N GLU 290.A O no hydrogen 3.215 N/A ASN 294.A ND2 LYS 263.A O no hydrogen 2.746 N/A ARG 295.A N LEU 291.A O no hydrogen 3.083 N/A ARG 295.A NH1 LEU 234.A O no hydrogen 3.118 N/A ARG 295.A NH1 PRO 235.A O no hydrogen 3.396 N/A ARG 295.A NH2 PRO 235.A O no hydrogen 3.073 N/A GLU 296.A N ALA 292.A O no hydrogen 3.079 N/A ILE 297.A N GLU 293.A O no hydrogen 2.856 N/A LEU 298.A N ASN 294.A O no hydrogen 3.043 N/A LYS 299.A N GLU 296.A O no hydrogen 3.106 N/A GLU 300.A N ILE 297.A O no hydrogen 3.331 N/A ASP 308.A N GLN 331.A OE1 no hydrogen 2.813 N/A SER 310.A N ASP 308.A OD1 no hydrogen 3.138 N/A SER 310.A OG ASP 308.A OD1 no hydrogen 2.925 N/A SER 310.A OG ASP 308.A OD2 no hydrogen 3.207 N/A LYS 311.A N ASP 308.A O no hydrogen 3.240 N/A LYS 311.A NZ ASP 308.A OD2 no hydrogen 2.641 N/A ILE 314.A N TYR 330.A O no hydrogen 2.725 N/A ALA 315.A N LYS 376.A O no hydrogen 2.924 N/A GLU 316.A N GLN 328.A O no hydrogen 2.959 N/A GLN 318.A N THR 326.A O no hydrogen 2.799 N/A GLN 318.A NE2 GLN 328.A OE1 no hydrogen 2.742 N/A LYS 319.A NZ ASP 352.A OD2 no hydrogen 2.777 N/A GLN 320.A N GLN 324.A O no hydrogen 2.940 N/A GLN 320.A NE2 THR 326.A OG1 no hydrogen 3.147 N/A GLN 320.A NE2 LYS 412.A O no hydrogen 3.025 N/A GLN 324.A N GLY 321.A O no hydrogen 3.164 N/A TRP 325.A N TYR 342.A O no hydrogen 2.886 N/A TRP 325.A NE1 GLN 355.A OE1 no hydrogen 2.836 N/A THR 326.A N GLN 318.A O no hydrogen 3.044 N/A THR 326.A OG1 GLN 318.A OE1 no hydrogen 2.522 N/A TYR 327.A N GLY 340.A O no hydrogen 2.938 N/A GLN 328.A N GLU 316.A O no hydrogen 2.998 N/A GLN 328.A NE2 GLN 318.A OE1 no hydrogen 2.970 N/A ILE 329.A N LYS 338.A O no hydrogen 2.798 N/A TYR 330.A N ILE 314.A O no hydrogen 2.874 N/A TYR 330.A OH GLU 316.A OE2 no hydrogen 2.690 N/A GLN 331.A NE2 ASP 308.A O no hydrogen 2.822 N/A GLN 331.A NE2 LYS 311.A O no hydrogen 3.276 N/A LYS 335.A N GLU 332.A O no hydrogen 2.949 N/A LYS 335.A NZ HIS 303.A O no hydrogen 3.372 N/A ASN 336.A ND2 TYR 415.A OH no hydrogen 3.529 N/A LEU 337.A N ILE 329.A O no hydrogen 2.698 N/A LYS 338.A N ILE 329.A O no hydrogen 3.289 N/A LYS 338.A NZ THR 228.A O no hydrogen 2.699 N/A LYS 338.A NZ TYR 327.A OH no hydrogen 3.146 N/A LYS 338.A NZ THR 339.A O no hydrogen 3.197 N/A THR 339.A OG1 GLN 230.A O no hydrogen 3.153 N/A GLY 340.A N TYR 327.A O no hydrogen 3.135 N/A LYS 341.A NZ GLN 324.A OE1 no hydrogen 3.098 N/A TYR 342.A N TRP 325.A O no hydrogen 2.742 N/A TYR 342.A OH GLU 366.A OE2 no hydrogen 2.424 N/A ASN 351.A N ALA 348.A O no hydrogen 3.061 N/A ASN 351.A ND2 TYR 393.A OH no hydrogen 2.867 N/A LYS 354.A N ASN 351.A OD1 no hydrogen 2.946 N/A GLN 355.A N ASN 351.A O no hydrogen 3.341 N/A GLN 355.A NE2 ALA 348.A O no hydrogen 2.469 N/A GLN 355.A NE2 ASN 351.A O no hydrogen 3.506 N/A LEU 356.A N ASP 352.A O no hydrogen 2.924 N/A THR 357.A N VAL 353.A O no hydrogen 2.821 N/A THR 357.A OG1 VAL 353.A O no hydrogen 2.639 N/A GLU 358.A N LYS 354.A O no hydrogen 3.098 N/A ALA 359.A N GLN 355.A O no hydrogen 2.922 N/A VAL 360.A N LEU 356.A O no hydrogen 2.800 N/A GLN 361.A N THR 357.A O no hydrogen 3.095 N/A GLN 361.A NE2 THR 357.A O no hydrogen 3.693 N/A GLN 361.A NE2 TYR 393.A O no hydrogen 3.685 N/A LYS 362.A N GLU 358.A O no hydrogen 2.956 N/A ILE 363.A N ALA 359.A O no hydrogen 2.978 N/A THR 364.A N VAL 360.A O no hydrogen 2.939 N/A THR 364.A OG1 VAL 360.A O no hydrogen 2.760 N/A THR 365.A N GLN 361.A O no hydrogen 2.909 N/A THR 365.A OG1 GLN 361.A O no hydrogen 3.228 N/A GLU 366.A N LYS 362.A O no hydrogen 2.903 N/A SER 367.A N ILE 363.A O no hydrogen 2.948 N/A SER 367.A OG LYS 373.A O no hydrogen 2.799 N/A ILE 368.A N THR 364.A O no hydrogen 2.812 N/A VAL 369.A N THR 365.A O no hydrogen 3.033 N/A ILE 370.A N GLU 366.A O no hydrogen 3.056 N/A TRP 371.A N SER 367.A O no hydrogen 2.894 N/A GLY 372.A N ILE 368.A O no hydrogen 2.720 N/A LYS 373.A NZ TYR 307.A OH no hydrogen 3.047 N/A LYS 373.A NZ LYS 311.A O no hydrogen 3.367 N/A LYS 376.A N LEU 313.A O no hydrogen 2.664 N/A PHE 377.A N GLU 401.A O no hydrogen 2.790 N/A LYS 378.A N ALA 315.A O no hydrogen 2.815 N/A LEU 379.A N GLU 403.A O no hydrogen 2.914 N/A ILE 381.A N LEU 379.A O no hydrogen 3.001 N/A THR 385.A N GLN 382.A O no hydrogen 3.078 N/A TRP 386.A N GLN 382.A O no hydrogen 3.124 N/A GLU 387.A N LYS 383.A O no hydrogen 2.844 N/A THR 388.A N GLU 384.A O no hydrogen 3.284 N/A THR 388.A N THR 385.A O no hydrogen 3.258 N/A THR 388.A OG1 GLU 384.A O no hydrogen 2.585 N/A TRP 389.A N TRP 386.A O no hydrogen 3.109 N/A TRP 390.A N TRP 386.A O no hydrogen 3.009 N/A GLU 392.A N TRP 389.A O no hydrogen 2.978 N/A TYR 393.A N TRP 390.A O no hydrogen 3.228 N/A TRP 394.A NE1 TRP 398.A O no hydrogen 2.940 N/A GLN 395.A N GLN 361.A OE1 no hydrogen 2.726 N/A ALA 396.A N GLN 361.A OE1 no hydrogen 2.852 N/A TRP 398.A NE1 ASP 182.A OD2 no hydrogen 3.000 N/A GLU 403.A N PHE 377.A O no hydrogen 2.595 N/A VAL 405.A N LEU 379.A O no hydrogen 2.883 N/A ASN 406.A ND2 GLN 382.A OE1 no hydrogen 2.932 N/A GLN 416.A N LEU 413.A O no hydrogen 3.204 N/A