Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8fhe_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 3.A N SER 6.A OG no hydrogen 2.859 N/A SER 6.A N ASN 3.A OD1 no hydrogen 2.977 N/A SER 6.A OG GLN 1.A O no hydrogen 2.897 N/A SER 6.A OG ASN 3.A O no hydrogen 3.073 N/A SER 6.A OG ASN 3.A OD1 no hydrogen 3.315 N/A ALA 7.A N ASN 3.A O no hydrogen 2.919 N/A ASP 8.A N PRO 4.A O no hydrogen 2.973 N/A LEU 9.A N GLU 5.A O no hydrogen 3.146 N/A ARG 10.A N SER 6.A O no hydrogen 2.887 N/A ARG 10.A NH1 GLN 205.A OE1 no hydrogen 2.845 N/A ARG 10.A NH2 GLN 205.A OE1 no hydrogen 3.166 N/A ALA 11.A N ALA 7.A O no hydrogen 2.846 N/A LEU 12.A N ASP 8.A O no hydrogen 2.919 N/A ALA 13.A N LEU 9.A O no hydrogen 2.964 N/A LYS 14.A N ARG 10.A O no hydrogen 2.968 N/A LYS 14.A NZ ASP 18.A OD2 no hydrogen 2.836 N/A HIS 15.A N ALA 11.A O no hydrogen 2.879 N/A HIS 15.A NE2 SER 87.A O no hydrogen 2.785 N/A LEU 16.A N LEU 12.A O no hydrogen 2.895 N/A TYR 17.A N ALA 13.A O no hydrogen 2.865 N/A ASP 18.A N LYS 14.A O no hydrogen 2.801 N/A SER 19.A N HIS 15.A O no hydrogen 2.963 N/A SER 19.A OG HIS 15.A O no hydrogen 2.879 N/A TYR 20.A N LEU 16.A O no hydrogen 2.698 N/A TYR 20.A OH ASP 166.A OD2 no hydrogen 2.757 N/A ILE 21.A N TYR 17.A O no hydrogen 2.912 N/A LYS 22.A N ASP 18.A O no hydrogen 3.103 N/A SER 23.A N SER 19.A O no hydrogen 2.877 N/A SER 23.A N TYR 20.A O no hydrogen 3.232 N/A SER 23.A OG SER 19.A O no hydrogen 2.890 N/A PHE 24.A N TYR 20.A O no hydrogen 2.960 N/A LYS 28.A N ASP 166.A OD2 no hydrogen 2.858 N/A LYS 28.A NZ LEU 164.A O no hydrogen 2.752 N/A ALA 29.A N ASP 166.A OD1 no hydrogen 3.103 N/A LYS 30.A N THR 27.A OG1 no hydrogen 3.276 N/A LYS 30.A NZ PRO 25.A O no hydrogen 2.643 N/A ALA 31.A N THR 27.A O no hydrogen 3.231 N/A ARG 32.A N LYS 28.A O no hydrogen 2.912 N/A ARG 32.A NH1 SER 117.A O no hydrogen 2.702 N/A ARG 32.A NH1 MET 119.A O no hydrogen 2.724 N/A ARG 32.A NH2 MET 119.A O no hydrogen 3.395 N/A ALA 33.A N ALA 29.A O no hydrogen 3.022 N/A ILE 34.A N LYS 30.A O no hydrogen 3.317 N/A LEU 35.A N ALA 31.A O no hydrogen 2.985 N/A THR 36.A N ARG 32.A O no hydrogen 2.960 N/A THR 36.A OG1 ARG 32.A O no hydrogen 2.823 N/A GLY 37.A N ILE 34.A O no hydrogen 3.117 N/A LYS 38.A N ALA 33.A O no hydrogen 2.770 N/A LYS 38.A NZ THR 36.A OG1 no hydrogen 2.975 N/A SER 43.A OG THR 39.A O no hydrogen 3.207 N/A PHE 45.A N GLN 130.A O no hydrogen 2.850 N/A ILE 47.A N PHE 132.A O no hydrogen 2.740 N/A TYR 48.A N SER 52.A OG no hydrogen 2.891 N/A ASP 49.A N SER 52.A OG no hydrogen 2.996 N/A SER 52.A N ASP 49.A OD2 no hydrogen 2.822 N/A SER 52.A OG ASP 49.A O no hydrogen 3.062 N/A SER 52.A OG ASP 49.A OD2 no hydrogen 2.588 N/A LEU 53.A N ASP 49.A O no hydrogen 2.882 N/A MET 54.A N MET 50.A O no hydrogen 3.182 N/A MET 55.A N ASN 51.A O no hydrogen 3.005 N/A GLY 56.A N LEU 53.A O no hydrogen 3.065 N/A GLU 57.A N MET 54.A O no hydrogen 3.407 N/A ARG 65.A N GLU 61.A O no hydrogen 3.017 N/A ARG 65.A NH1 GLN 255.A OE1 no hydrogen 3.098 N/A ILE 66.A N VAL 62.A O no hydrogen 2.932 N/A PHE 67.A N ALA 63.A O no hydrogen 2.996 N/A GLN 68.A N ILE 64.A O no hydrogen 2.850 N/A GLY 69.A N ARG 65.A O no hydrogen 2.927 N/A CYS 70.A N ILE 66.A O no hydrogen 2.853 N/A CYS 70.A SG ILE 66.A O no hydrogen 3.808 N/A CYS 70.A SG PHE 67.A O no hydrogen 3.374 N/A GLN 71.A N.A PHE 67.A O no hydrogen 2.961 N/A GLN 71.A N.B PHE 67.A O no hydrogen 2.942 N/A GLN 71.A NE2.B TYR 262.A OH no hydrogen 3.048 N/A PHE 72.A N GLN 68.A O no hydrogen 2.992 N/A ARG 73.A N GLY 69.A O no hydrogen 2.900 N/A ARG 73.A NH1 ASP 260.A OD1 no hydrogen 2.683 N/A ARG 73.A NH2 GLU 256.A OE1 no hydrogen 2.266 N/A SER 74.A N GLN 71.A O.A no hydrogen 3.311 N/A SER 74.A N GLN 71.A O.B no hydrogen 2.997 N/A SER 74.A OG CYS 70.A O no hydrogen 2.615 N/A VAL 75.A N PHE 72.A O no hydrogen 3.108 N/A VAL 78.A N SER 74.A O no hydrogen 2.916 N/A GLN 79.A N VAL 75.A O no hydrogen 2.909 N/A GLU 80.A N GLU 76.A O no hydrogen 2.883 N/A ILE 81.A N ALA 77.A O no hydrogen 2.826 N/A THR 82.A N VAL 78.A O no hydrogen 2.918 N/A THR 82.A OG1 VAL 78.A O no hydrogen 2.954 N/A GLU 83.A N GLN 79.A O no hydrogen 2.918 N/A TYR 84.A N GLU 80.A O no hydrogen 2.900 N/A TYR 84.A OH ALA 170.A O no hydrogen 2.593 N/A ALA 85.A N ILE 81.A O no hydrogen 2.857 N/A LYS 86.A N THR 82.A O no hydrogen 3.076 N/A LYS 86.A NZ GLU 83.A OE2 no hydrogen 3.302 N/A SER 87.A N TYR 84.A O no hydrogen 2.914 N/A SER 87.A OG TYR 84.A O no hydrogen 2.585 N/A ILE 88.A N ALA 85.A O no hydrogen 2.970 N/A PHE 91.A N ILE 88.A O no hydrogen 2.936 N/A ASN 93.A N GLY 90.A O no hydrogen 3.259 N/A LEU 94.A N PHE 91.A O no hydrogen 3.033 N/A GLN 99.A N ASP 95.A O no hydrogen 3.019 N/A GLN 99.A NE2 LEU 94.A O no hydrogen 2.763 N/A VAL 100.A N LEU 96.A O no hydrogen 2.995 N/A THR 101.A N ASN 97.A O no hydrogen 2.902 N/A THR 101.A OG1 ASN 97.A O no hydrogen 3.140 N/A LEU 102.A N ASP 98.A O no hydrogen 2.812 N/A LEU 103.A N GLN 99.A O no hydrogen 3.045 N/A LYS 104.A N VAL 100.A O no hydrogen 2.740 N/A TYR 105.A N THR 101.A O no hydrogen 3.239 N/A GLY 106.A N LEU 102.A O no hydrogen 2.940 N/A VAL 107.A N LEU 103.A O no hydrogen 2.925 N/A HIS 108.A ND1 TYR 262.A OH no hydrogen 2.602 N/A ILE 110.A N GLY 106.A O no hydrogen 2.970 N/A ILE 111.A N VAL 107.A O no hydrogen 2.827 N/A TYR 112.A N HIS 108.A O no hydrogen 3.073 N/A TYR 112.A OH TYR 262.A OXT no hydrogen 2.448 N/A THR 113.A N GLU 109.A O no hydrogen 3.020 N/A THR 113.A OG1 GLU 109.A O no hydrogen 2.910 N/A MET 114.A N ILE 110.A O no hydrogen 2.931 N/A LEU 115.A N ILE 111.A O no hydrogen 2.779 N/A ALA 116.A N TYR 112.A O no hydrogen 3.090 N/A SER 117.A N MET 114.A O no hydrogen 3.128 N/A LEU 118.A N LEU 115.A O no hydrogen 2.883 N/A MET 119.A N ALA 116.A O no hydrogen 2.981 N/A ASN 120.A N GLY 123.A O no hydrogen 2.947 N/A ASP 122.A N ASN 120.A OD1 no hydrogen 2.862 N/A GLY 123.A N ASN 120.A O no hydrogen 3.351 N/A GLY 123.A N ASN 120.A OD1 no hydrogen 3.114 N/A VAL 124.A N MET 133.A O no hydrogen 2.849 N/A LEU 125.A N LEU 118.A O no hydrogen 2.923 N/A ILE 126.A N GLY 131.A O no hydrogen 2.931 N/A SER 127.A N ASP 260.A OD2 no hydrogen 2.910 N/A GLN 130.A N SER 127.A O no hydrogen 2.982 N/A GLY 131.A N ILE 126.A O no hydrogen 3.114 N/A PHE 132.A N PHE 45.A O no hydrogen 2.777 N/A MET 133.A N VAL 124.A O no hydrogen 2.880 N/A THR 134.A N ILE 47.A O no hydrogen 3.075 N/A ARG 135.A N ASP 122.A O no hydrogen 2.791 N/A ARG 135.A NE GLU 150.A OE1 no hydrogen 3.277 N/A ARG 135.A NE GLU 150.A OE2 no hydrogen 2.982 N/A ARG 135.A NH1 LYS 121.A O no hydrogen 3.336 N/A ARG 135.A NH2 GLU 150.A OE1 no hydrogen 2.849 N/A PHE 137.A N THR 134.A OG1 no hydrogen 3.057 N/A LEU 138.A N THR 134.A O no hydrogen 3.147 N/A LYS 139.A N ARG 135.A O no hydrogen 2.951 N/A SER 140.A N GLU 136.A O no hydrogen 2.942 N/A SER 140.A N PHE 137.A O no hydrogen 3.100 N/A SER 140.A OG PHE 137.A O no hydrogen 2.730 N/A LEU 141.A N LEU 138.A O no hydrogen 3.273 N/A ARG 142.A NH1 SER 249.A O no hydrogen 2.853 N/A GLY 146.A N ARG 142.A O no hydrogen 3.298 N/A ASP 147.A N PRO 144.A O no hydrogen 3.272 N/A PHE 148.A N PHE 145.A O no hydrogen 3.073 N/A LYS 152.A NZ PHE 148.A O no hydrogen 3.137 N/A LYS 152.A NZ TYR 262.A O no hydrogen 2.671 N/A LYS 152.A NZ TYR 262.A OXT no hydrogen 3.306 N/A PHE 153.A N MET 149.A O no hydrogen 3.079 N/A GLU 154.A N GLU 150.A O no hydrogen 2.948 N/A PHE 155.A N PRO 151.A O no hydrogen 3.072 N/A ALA 156.A N LYS 152.A O no hydrogen 2.830 N/A VAL 157.A N PHE 153.A O no hydrogen 2.938 N/A LYS 158.A N GLU 154.A O no hydrogen 3.510 N/A PHE 159.A N PHE 155.A O no hydrogen 2.808 N/A ASN 160.A N ALA 156.A O no hydrogen 2.731 N/A ASN 160.A ND2 ALA 116.A O no hydrogen 2.975 N/A ALA 161.A N VAL 157.A O no hydrogen 3.098 N/A ALA 161.A N LYS 158.A O no hydrogen 3.255 N/A LEU 162.A N PHE 159.A O no hydrogen 3.013 N/A GLU 163.A N ASN 160.A O no hydrogen 2.921 N/A ASP 165.A N ASP 168.A OD2 no hydrogen 2.934 N/A ASP 168.A N ASP 165.A OD1 no hydrogen 2.894 N/A LEU 169.A N ASP 165.A O no hydrogen 2.875 N/A ALA 170.A N ASP 166.A O no hydrogen 2.899 N/A ILE 171.A N ASP 168.A O no hydrogen 3.097 N/A PHE 172.A N ASP 168.A O no hydrogen 3.058 N/A ILE 173.A N LEU 169.A O no hydrogen 2.839 N/A ALA 174.A N ALA 170.A O no hydrogen 3.259 N/A VAL 175.A N ILE 171.A O no hydrogen 2.889 N/A ILE 176.A N PHE 172.A O no hydrogen 3.019 N/A ILE 177.A N ILE 173.A O no hydrogen 3.096 N/A LEU 178.A N ALA 174.A O no hydrogen 3.107 N/A SER 179.A OG ILE 176.A O no hydrogen 2.658 N/A ARG 182.A NH1 GLU 109.A OE2 no hydrogen 2.742 N/A ARG 182.A NH2 GLU 109.A OE1 no hydrogen 2.773 N/A ARG 182.A NH2 GLU 109.A OE2 no hydrogen 3.389 N/A ARG 182.A NH2 ILE 176.A O no hydrogen 3.427 N/A LEU 186.A N ASP 98.A OD1 no hydrogen 2.877 N/A LEU 186.A N ASP 98.A OD2 no hydrogen 3.196 N/A ASN 187.A N ASP 98.A OD2 no hydrogen 2.931 N/A LYS 189.A NZ ASP 193.A OD1 no hydrogen 2.978 N/A LYS 189.A NZ ASP 193.A OD2 no hydrogen 3.261 N/A GLU 192.A N VAL 188.A O no hydrogen 2.935 N/A ASP 193.A N LYS 189.A O no hydrogen 2.868 N/A ILE 194.A N PRO 190.A O no hydrogen 3.268 N/A GLN 195.A N ILE 191.A O no hydrogen 2.842 N/A GLN 195.A NE2 VAL 175.A O no hydrogen 3.057 N/A ASP 196.A N GLU 192.A O no hydrogen 2.769 N/A ASN 197.A N ASP 193.A O no hydrogen 3.324 N/A LEU 198.A N ILE 194.A O no hydrogen 2.922 N/A LEU 199.A N GLN 195.A O no hydrogen 2.695 N/A GLN 200.A N ASP 196.A O no hydrogen 2.968 N/A ALA 201.A N ASN 197.A O no hydrogen 2.995 N/A LEU 202.A N LEU 198.A O no hydrogen 2.800 N/A GLU 203.A N LEU 199.A O no hydrogen 2.866 N/A LEU 204.A N GLN 200.A O no hydrogen 3.177 N/A GLN 205.A N ALA 201.A O no hydrogen 2.970 N/A GLN 205.A NE2 ASP 168.A OD1 no hydrogen 2.901 N/A LEU 206.A N LEU 202.A O no hydrogen 2.897 N/A LYS 207.A N GLU 203.A O no hydrogen 3.067 N/A LEU 208.A N LEU 204.A O no hydrogen 2.977 N/A ASN 209.A N GLN 205.A O no hydrogen 2.960 N/A ASN 209.A ND2 ASP 165.A OD2 no hydrogen 2.958 N/A ASN 209.A ND2 ASP 168.A OD1 no hydrogen 2.941 N/A ASN 209.A ND2 ASP 168.A OD2 no hydrogen 3.264 N/A HIS 210.A N LEU 206.A O no hydrogen 2.911 N/A HIS 210.A ND1 GLU 212.A OE2 no hydrogen 2.951 N/A HIS 210.A NE2 ASP 168.A OD2 no hydrogen 2.624 N/A GLU 212.A N GLU 212.A OE1 no hydrogen 2.621 N/A SER 213.A N HIS 210.A O no hydrogen 3.332 N/A LYS 219.A N GLN 215.A O no hydrogen 2.801 N/A LEU 220.A N LEU 216.A O no hydrogen 2.759 N/A LEU 221.A N PHE 217.A O no hydrogen 3.002 N/A GLN 222.A N ALA 218.A O no hydrogen 2.903 N/A LYS 223.A N LYS 219.A O no hydrogen 3.171 N/A LYS 223.A N LEU 220.A O no hydrogen 2.982 N/A MET 224.A N LEU 221.A O no hydrogen 3.130 N/A THR 225.A N GLN 222.A O no hydrogen 2.951 N/A ASP 226.A N GLN 222.A O no hydrogen 3.245 N/A LEU 227.A N LYS 223.A O no hydrogen 2.877 N/A ARG 228.A N MET 224.A O no hydrogen 3.241 N/A ARG 228.A NH1 ASP 181.A OD1 no hydrogen 3.270 N/A ARG 228.A NH2 ASP 181.A OD1 no hydrogen 2.862 N/A GLN 229.A N THR 225.A O no hydrogen 3.386 N/A ILE 230.A N ASP 226.A O no hydrogen 3.146 N/A VAL 231.A N LEU 227.A O no hydrogen 3.083 N/A THR 232.A N ARG 228.A O no hydrogen 2.861 N/A THR 232.A OG1 ARG 228.A O no hydrogen 3.411 N/A THR 232.A OG1 GLN 229.A O no hydrogen 3.041 N/A GLU 233.A N GLN 229.A O no hydrogen 2.830 N/A HIS 234.A N VAL 231.A O no hydrogen 3.044 N/A VAL 235.A N THR 232.A O no hydrogen 2.995 N/A LEU 237.A N GLU 233.A O no hydrogen 2.982 N/A LEU 238.A N HIS 234.A O no hydrogen 3.047 N/A GLN 239.A N VAL 235.A O no hydrogen 3.267 N/A VAL 240.A N GLN 236.A O no hydrogen 2.908 N/A ILE 241.A N LEU 237.A O no hydrogen 2.900 N/A LYS 242.A N LEU 238.A O no hydrogen 3.042 N/A LYS 243.A N GLN 239.A O no hydrogen 3.066 N/A THR 244.A N ILE 241.A O no hydrogen 3.052 N/A THR 244.A OG1 VAL 240.A O no hydrogen 2.799 N/A SER 249.A N ASP 247.A OD1 no hydrogen 2.776 N/A SER 249.A OG ASP 247.A OD1 no hydrogen 2.809 N/A LEU 253.A N HIS 251.A ND1 no hydrogen 3.054 N/A GLN 255.A N HIS 251.A O no hydrogen 2.962 N/A GLN 255.A NE2 LEU 250.A O no hydrogen 2.872 N/A GLU 256.A N PRO 252.A O no hydrogen 3.021 N/A ILE 257.A N LEU 253.A O no hydrogen 2.973 N/A TYR 258.A N LEU 254.A O no hydrogen 2.903 N/A LYS 259.A N GLN 255.A O no hydrogen 3.029 N/A LYS 259.A NZ GLU 256.A OE2 no hydrogen 3.518 N/A ASP 260.A N ILE 257.A O no hydrogen 2.936 N/A LEU 261.A N TYR 258.A O no hydrogen 2.923 N/A TYR 262.A OH HIS 108.A ND1 no hydrogen 2.602 N/A