Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8fl3_LN.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 9.A NH1 SER 263.A O no hydrogen 2.581 N/A ARG 9.A NH2 SER 263.A O no hydrogen 2.669 N/A GLY 14.A N SER 12.A OG no hydrogen 3.168 N/A ARG 18.A NH2 SER 12.A O no hydrogen 3.420 N/A ARG 20.A NE GLN 269.A OE1 no hydrogen 3.101 N/A SER 21.A N TYR 272.A O no hydrogen 3.169 N/A SER 21.A OG ARG 23.A O no hydrogen 2.845 N/A HIS 24.A ND1 TYR 272.A OH no hydrogen 2.924 N/A LYS 27.A N HIS 274.A NE2 no hydrogen 3.089 N/A SER 30.A OG LYS 29.A O no hydrogen 2.896 N/A LYS 33.A NZ ASP 34.A O no hydrogen 3.125 N/A SER 37.A OG ASP 35.A OD2 no hydrogen 2.828 N/A LYS 38.A N ASP 35.A O no hydrogen 3.129 N/A HIS 41.A N ASN 185.A O no hydrogen 3.005 N/A HIS 41.A ND1 LEU 42.A O no hydrogen 2.785 N/A THR 43.A OG1 GLN 183.A O no hydrogen 2.670 N/A PHE 45.A N LEU 345.A O no hydrogen 2.967 N/A GLY 47.A N LEU 343.A O no hydrogen 2.606 N/A TYR 48.A N GLU 79.A O no hydrogen 3.205 N/A TYR 48.A OH THR 165.A OG1 no hydrogen 3.343 N/A TYR 48.A OH HIS 178.A ND1 no hydrogen 2.855 N/A LYS 49.A N ARG 341.A O no hydrogen 3.217 N/A LYS 49.A NZ VAL 335.A O no hydrogen 3.326 N/A LYS 49.A NZ GLY 337.A O no hydrogen 2.931 N/A ALA 50.A N ILE 77.A O no hydrogen 2.951 N/A GLY 51.A N ILE 77.A O no hydrogen 3.387 N/A THR 53.A N VAL 75.A O no hydrogen 2.989 N/A THR 53.A OG1 HIS 54.A O no hydrogen 3.569 N/A THR 53.A OG1 ASP 367.A O no hydrogen 3.313 N/A HIS 54.A N THR 53.A OG1 no hydrogen 2.727 N/A ILE 55.A N GLU 73.A O no hydrogen 2.943 N/A VAL 56.A N PHE 365.A O no hydrogen 2.967 N/A ARG 57.A N VAL 71.A O no hydrogen 3.254 N/A ARG 57.A NE GLU 73.A OE1 no hydrogen 2.792 N/A VAL 59.A N LYS 69.A O no hydrogen 3.106 N/A ARG 61.A N ASN 67.A OD1 no hydrogen 3.250 N/A VAL 66.A N SER 64.A OG no hydrogen 3.318 N/A LYS 68.A N VAL 59.A O no hydrogen 3.028 N/A LYS 68.A NZ ASP 60.A OD1 no hydrogen 3.023 N/A LYS 69.A NZ ASN 67.A O no hydrogen 3.344 N/A VAL 71.A N ARG 57.A O no hydrogen 3.017 N/A GLU 73.A N ILE 55.A O no hydrogen 3.306 N/A VAL 75.A N THR 53.A O no hydrogen 2.864 N/A THR 76.A N LEU 331.A O no hydrogen 2.825 N/A THR 76.A OG1 GLY 333.A O no hydrogen 2.701 N/A ILE 77.A N GLY 51.A O no hydrogen 2.704 N/A VAL 78.A N VAL 329.A O no hydrogen 2.961 N/A GLU 79.A N TYR 48.A O no hydrogen 2.805 N/A THR 80.A N ASP 327.A O no hydrogen 2.672 N/A THR 80.A OG1 ASP 327.A O no hydrogen 3.230 N/A VAL 84.A N HIS 164.A O no hydrogen 2.886 N/A VAL 85.A N GLN 202.A O no hydrogen 3.067 N/A VAL 86.A N ILE 162.A O no hydrogen 2.853 N/A ILE 88.A N VAL 104.A O no hydrogen 2.925 N/A VAL 89.A N ARG 160.A O no hydrogen 2.926 N/A GLY 90.A N LYS 102.A O no hydrogen 3.126 N/A TYR 91.A N VAL 158.A O no hydrogen 3.045 N/A TYR 91.A OH GLU 181.A OE1 no hydrogen 2.494 N/A TYR 91.A OH GLU 181.A OE2 no hydrogen 3.319 N/A VAL 92.A N ARG 99.A O no hydrogen 2.739 N/A GLU 93.A N GLN 157.A OE1 no hydrogen 2.841 N/A THR 94.A OG1 GLY 97.A O no hydrogen 2.197 N/A GLY 97.A N THR 94.A O no hydrogen 2.957 N/A ARG 99.A N VAL 92.A O no hydrogen 3.006 N/A PHE 101.A N GLY 90.A O no hydrogen 2.634 N/A LYS 102.A NZ ASP 148.A OD1 no hydrogen 2.973 N/A VAL 104.A N ILE 88.A O no hydrogen 2.965 N/A PHE 105.A N TYR 132.A OH no hydrogen 2.941 N/A ALA 106.A N VAL 86.A O no hydrogen 2.719 N/A LYS 114.A N SER 110.A O no hydrogen 2.946 N/A LYS 114.A NZ LYS 126.A O no hydrogen 3.357 N/A LYS 114.A NZ ALA 128.A O no hydrogen 3.303 N/A ARG 115.A N ASP 111.A O no hydrogen 2.867 N/A ARG 116.A N CYS 113.A O no hydrogen 3.139 N/A ARG 116.A NE ALA 177.A O no hydrogen 2.803 N/A ARG 116.A NH2 ALA 177.A O no hydrogen 2.976 N/A PHE 117.A N LYS 114.A O no hydrogen 3.172 N/A TYR 118.A N ARG 115.A O no hydrogen 3.055 N/A SER 124.A N TRP 121.A O no hydrogen 3.317 N/A SER 124.A OG TRP 121.A O no hydrogen 3.137 N/A LYS 126.A N SER 124.A OG no hydrogen 3.402 N/A LYS 126.A NZ SER 124.A O no hydrogen 3.393 N/A THR 130.A N LYS 127.A O no hydrogen 3.310 N/A THR 130.A OG1 LYS 127.A O no hydrogen 2.589 N/A TYR 132.A OH PHE 105.A O no hydrogen 3.355 N/A CYS 133.A N PHE 129.A O no hydrogen 3.230 N/A CYS 133.A SG THR 130.A O no hydrogen 3.576 N/A LYS 134.A N LYS 131.A O no hydrogen 3.407 N/A LYS 135.A N TYR 132.A O no hydrogen 3.095 N/A ASP 138.A N LYS 134.A O no hydrogen 3.317 N/A LYS 142.A N ASP 138.A O no hydrogen 2.942 N/A LYS 142.A NZ TRP 136.A O no hydrogen 2.329 N/A LYS 143.A N GLU 139.A O no hydrogen 3.209 N/A GLN 144.A N ASP 140.A O no hydrogen 3.163 N/A LEU 145.A N GLY 141.A O no hydrogen 2.970 N/A GLU 146.A N LYS 142.A O no hydrogen 2.912 N/A LYS 147.A N LYS 143.A O no hydrogen 2.949 N/A ASP 148.A N GLN 144.A O no hydrogen 2.989 N/A PHE 149.A N LEU 145.A O no hydrogen 3.161 N/A SER 150.A N GLU 146.A O no hydrogen 2.918 N/A SER 150.A OG GLU 146.A O no hydrogen 2.989 N/A SER 151.A N LYS 147.A O no hydrogen 2.738 N/A MET 152.A N ASP 148.A O no hydrogen 2.826 N/A LYS 153.A N PHE 149.A O no hydrogen 2.903 N/A LYS 154.A N SER 150.A O no hydrogen 3.207 N/A LYS 154.A N SER 151.A O no hydrogen 3.214 N/A TYR 155.A N SER 151.A O no hydrogen 3.209 N/A CYS 156.A N MET 152.A O no hydrogen 3.218 N/A GLN 157.A N TYR 91.A O no hydrogen 3.141 N/A GLN 157.A NE2 TYR 155.A O no hydrogen 3.397 N/A ARG 160.A N VAL 89.A O no hydrogen 2.883 N/A ARG 160.A NH1 GLU 181.A OE1 no hydrogen 3.256 N/A VAL 161.A N ILE 182.A O no hydrogen 2.992 N/A ILE 162.A N GLY 87.A O no hydrogen 2.924 N/A ALA 163.A N MET 180.A O no hydrogen 2.870 N/A HIS 164.A N VAL 84.A O no hydrogen 2.926 N/A HIS 164.A ND1 THR 165.A O no hydrogen 2.627 N/A THR 165.A N HIS 178.A O no hydrogen 3.301 N/A THR 165.A OG1 TYR 48.A OH no hydrogen 3.343 N/A GLN 166.A NE2 PRO 82.A O no hydrogen 2.995 N/A ARG 168.A N GLU 112.A OE1 no hydrogen 3.327 N/A GLN 174.A NE2 LYS 176.A O no hydrogen 2.465 N/A ALA 177.A N GLU 112.A O no hydrogen 3.207 N/A HIS 178.A N THR 165.A OG1 no hydrogen 3.387 N/A HIS 178.A ND1 TYR 48.A OH no hydrogen 2.855 N/A MET 180.A N ALA 163.A O no hydrogen 2.912 N/A ILE 182.A N VAL 161.A O no hydrogen 2.911 N/A GLN 183.A NE2 ASN 185.A OD1 no hydrogen 3.043 N/A VAL 184.A N ILE 159.A O no hydrogen 3.065 N/A ASN 185.A N HIS 41.A O no hydrogen 3.032 N/A ASN 185.A ND2 PRO 32.A O no hydrogen 2.866 N/A GLY 186.A N ASP 34.A OD1 no hydrogen 2.664 N/A GLY 187.A N PRO 36.A O no hydrogen 3.224 N/A GLU 191.A N THR 188.A OG1 no hydrogen 3.394 N/A LYS 192.A N THR 188.A O no hydrogen 3.042 N/A LYS 192.A NZ ASP 34.A OD2 no hydrogen 2.564 N/A LYS 192.A NZ VAL 184.A O no hydrogen 3.466 N/A LEU 193.A N VAL 189.A O no hydrogen 3.257 N/A ASP 194.A N ALA 190.A O no hydrogen 3.190 N/A TRP 195.A N GLU 191.A O no hydrogen 2.770 N/A ALA 196.A N LYS 192.A O no hydrogen 2.687 N/A ARG 197.A N LEU 193.A O no hydrogen 2.777 N/A GLU 198.A N ASP 194.A O no hydrogen 3.334 N/A LEU 200.A N ARG 197.A O no hydrogen 3.202 N/A GLU 201.A N VAL 85.A O no hydrogen 2.809 N/A GLN 202.A N ARG 199.A O no hydrogen 2.788 N/A VAL 204.A N MET 83.A O no hydrogen 2.853 N/A GLN 208.A N PRO 205.A O no hydrogen 3.466 N/A ASP 213.A N ILE 282.A O no hydrogen 3.204 N/A GLU 214.A N GLY 211.A O no hydrogen 3.424 N/A ILE 216.A N LYS 280.A O no hydrogen 3.214 N/A ASP 217.A N ARG 346.A O no hydrogen 2.924 N/A VAL 218.A N GLU 277.A O no hydrogen 2.905 N/A ILE 219.A N THR 344.A O no hydrogen 2.895 N/A GLY 220.A N ARG 275.A O no hydrogen 3.337 N/A THR 222.A N HIS 273.A O no hydrogen 2.984 N/A LYS 225.A N LYS 270.A O no hydrogen 2.943 N/A LYS 228.A N GLY 268.A O no hydrogen 2.818 N/A LYS 228.A NZ LYS 225.A O no hydrogen 3.251 N/A SER 232.A N GLY 229.A O no hydrogen 3.241 N/A ARG 233.A N GLY 229.A O no hydrogen 2.571 N/A ARG 233.A NE GLN 269.A O no hydrogen 2.693 N/A ARG 233.A NH1 ARG 266.A O no hydrogen 3.046 N/A ARG 233.A NH2 ARG 18.A O no hydrogen 2.997 N/A ARG 233.A NH2 GLN 269.A O no hydrogen 2.970 N/A TRP 234.A N VAL 230.A O no hydrogen 2.890 N/A HIS 235.A N VAL 230.A O no hydrogen 3.110 N/A LEU 239.A N LEU 246.A O no hydrogen 3.091 N/A THR 243.A OG1 PRO 240.A O no hydrogen 2.894 N/A CYS 251.A SG GLY 253.A O no hydrogen 3.300 N/A ARG 259.A N PRO 257.A O no hydrogen 2.644 N/A VAL 264.A N ALA 261.A O no hydrogen 3.363 N/A GLY 268.A N LYS 228.A O no hydrogen 2.827 N/A GLN 269.A NE2 GLY 271.A O no hydrogen 3.363 N/A LYS 270.A N GLY 226.A O no hydrogen 2.922 N/A LYS 270.A NZ SER 232.A O no hydrogen 3.261 N/A LYS 270.A NZ SER 232.A OG no hydrogen 3.168 N/A TYR 272.A N LYS 223.A O no hydrogen 2.940 N/A TYR 272.A OH HIS 24.A ND1 no hydrogen 2.924 N/A HIS 273.A N THR 222.A OG1 no hydrogen 3.049 N/A HIS 273.A ND1 LYS 19.A O no hydrogen 2.754 N/A ARG 275.A N GLY 220.A O no hydrogen 3.118 N/A ARG 275.A NH1 HIS 274.A O no hydrogen 2.600 N/A GLU 277.A N VAL 218.A O no hydrogen 3.077 N/A LYS 280.A N ILE 216.A O no hydrogen 2.985 N/A LYS 280.A NZ GLU 277.A OE2 no hydrogen 3.180 N/A LYS 280.A NZ CYS 334.A O no hydrogen 2.927 N/A LYS 281.A NZ ASP 213.A O no hydrogen 3.114 N/A LYS 281.A NZ ARG 356.A O no hydrogen 3.067 N/A LYS 281.A NZ GLU 359.A O no hydrogen 3.282 N/A ILE 282.A N GLU 214.A O no hydrogen 2.816 N/A TYR 283.A N MET 330.A O no hydrogen 2.911 N/A TYR 283.A OH GLU 73.A OE1 no hydrogen 2.458 N/A LYS 284.A NZ ASN 300.A O no hydrogen 3.272 N/A GLY 286.A N PHE 328.A O no hydrogen 2.810 N/A TYR 289.A N THR 325.A O no hydrogen 3.068 N/A TYR 289.A OH SER 311.A OG no hydrogen 3.244 N/A LYS 292.A N LYS 295.A O no hydrogen 3.406 N/A ILE 297.A N LEU 290.A O no hydrogen 2.904 N/A ASN 300.A N LYS 298.A O no hydrogen 2.623 N/A ALA 301.A N LYS 310.A O no hydrogen 3.143 N/A SER 302.A OG SER 308.A O no hydrogen 2.975 N/A SER 302.A OG ASP 309.A OD1 no hydrogen 3.450 N/A THR 303.A OG1 LYS 364.A O no hydrogen 2.614 N/A ASP 306.A N THR 303.A OG1 no hydrogen 3.252 N/A LYS 310.A NZ ILE 366.A O no hydrogen 3.236 N/A LYS 310.A NZ GLN 378.A OE1 no hydrogen 3.329 N/A SER 311.A OG TYR 289.A OH no hydrogen 3.244 N/A ASN 313.A N SER 311.A OG no hydrogen 3.410 N/A ASN 313.A ND2 TYR 289.A OH no hydrogen 3.508 N/A ASN 313.A ND2 VAL 324.A O no hydrogen 2.805 N/A LEU 315.A N THR 368.A O no hydrogen 3.183 N/A GLY 317.A N PRO 314.A O no hydrogen 2.893 N/A PHE 318.A N GLY 322.A O no hydrogen 3.021 N/A TYR 321.A N PHE 318.A O no hydrogen 3.462 N/A TYR 321.A OH GLU 79.A OE1 no hydrogen 2.526 N/A GLY 322.A N PHE 318.A O no hydrogen 3.341 N/A VAL 324.A N ASN 313.A OD1 no hydrogen 2.744 N/A THR 325.A N GLU 79.A OE2 no hydrogen 3.368 N/A ASN 326.A ND2 GLU 79.A OE2 no hydrogen 3.319 N/A VAL 329.A N VAL 78.A O no hydrogen 2.788 N/A MET 330.A N LYS 284.A O no hydrogen 2.935 N/A LEU 331.A N THR 76.A O no hydrogen 2.920 N/A LYS 332.A N LYS 281.A O no hydrogen 2.961 N/A LYS 332.A NZ GLU 73.A OE2 no hydrogen 2.864 N/A GLY 333.A N ALA 74.A O no hydrogen 2.894 N/A LYS 340.A NZ HIS 320.A O no hydrogen 2.555 N/A ARG 341.A N THR 338.A O no hydrogen 3.228 N/A ARG 341.A NH1 THR 222.A O no hydrogen 3.133 N/A LEU 343.A N GLY 47.A O no hydrogen 2.499 N/A THR 344.A N ILE 219.A O no hydrogen 2.908 N/A THR 344.A OG1 GLY 26.A O no hydrogen 2.930 N/A THR 344.A OG1 ILE 219.A O no hydrogen 3.488 N/A LEU 345.A N PHE 45.A O no hydrogen 3.191 N/A ARG 346.A N ASP 217.A O no hydrogen 2.991 N/A ARG 346.A NH2 ASP 217.A OD2 no hydrogen 2.753 N/A LYS 347.A N THR 43.A O no hydrogen 3.237 N/A LYS 347.A NZ VAL 209.A O no hydrogen 3.054 N/A LYS 347.A NZ GLU 214.A OE1 no hydrogen 3.135 N/A SER 348.A OG LEU 350.A O no hydrogen 2.859 N/A LYS 364.A N VAL 56.A O no hydrogen 2.893 N/A LYS 364.A NZ GLU 70.A OE1 no hydrogen 3.348 N/A PHE 365.A N VAL 56.A O no hydrogen 3.343 N/A ASP 367.A N HIS 54.A O no hydrogen 3.190 N/A THR 368.A N GLN 378.A OE1 no hydrogen 2.516 N/A THR 368.A OG1 ILE 366.A O no hydrogen 3.325 N/A THR 369.A OG1 ASP 367.A OD2 no hydrogen 2.893 N/A SER 370.A OG LEU 315.A O no hydrogen 3.194 N/A LYS 371.A NZ THR 369.A O no hydrogen 2.650 N/A PHE 372.A N SER 370.A OG no hydrogen 3.253 N/A GLN 378.A N GLU 382.A OE1 no hydrogen 2.983 N/A GLN 378.A NE2 ASP 367.A OD1 no hydrogen 2.873 N/A GLU 381.A N GLU 381.A OE1 no hydrogen 2.572 N/A GLU 382.A N THR 379.A OG1 no hydrogen 3.226 N/A LYS 383.A N THR 379.A O no hydrogen 3.165 N/A LYS 384.A N MET 380.A O no hydrogen 2.870 N/A ALA 385.A N GLU 381.A O no hydrogen 2.987 N/A PHE 386.A N GLU 382.A O no hydrogen 3.073 N/A MET 387.A N LYS 383.A O no hydrogen 3.131 N/A GLY 388.A N LYS 384.A O no hydrogen 2.923 N/A LEU 390.A N ASP 393.A OD2 no hydrogen 3.403 N/A ARG 394.A N LEU 390.A O no hydrogen 3.246 N/A ILE 395.A N LYS 391.A O no hydrogen 2.972 N/A ALA 396.A N LYS 392.A O no hydrogen 3.011 N/A LYS 397.A N ASP 393.A O no hydrogen 3.185 N/A GLU 398.A N ARG 394.A O no hydrogen 2.992 N/A GLU 399.A N ILE 395.A O no hydrogen 2.710 N/A GLY 400.A N ALA 396.A O no hydrogen 2.742 N/A ALA 401.A N LYS 397.A O no hydrogen 2.804 N/A