Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8flc_LN.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 9.A NE GLY 11.A O no hydrogen 3.244 N/A ARG 9.A NH1 SER 263.A O no hydrogen 3.147 N/A GLY 14.A N SER 12.A OG no hydrogen 3.198 N/A ARG 20.A NH1 GLN 269.A OE1 no hydrogen 2.854 N/A SER 21.A N TYR 272.A O no hydrogen 3.245 N/A SER 21.A OG ARG 23.A O no hydrogen 2.822 N/A SER 21.A OG TYR 272.A O no hydrogen 3.442 N/A HIS 24.A ND1 TYR 272.A OH no hydrogen 2.758 N/A LYS 27.A N HIS 274.A NE2 no hydrogen 3.186 N/A SER 37.A N ASP 35.A OD1 no hydrogen 3.317 N/A SER 37.A OG ASP 35.A OD1 no hydrogen 3.078 N/A SER 37.A OG ASP 35.A OD2 no hydrogen 2.737 N/A LYS 38.A N ASP 35.A O no hydrogen 3.301 N/A HIS 41.A N ASN 185.A O no hydrogen 3.003 N/A HIS 41.A ND1 LEU 42.A O no hydrogen 2.854 N/A THR 43.A OG1 GLN 183.A O no hydrogen 2.816 N/A PHE 45.A N LEU 345.A O no hydrogen 2.875 N/A GLY 47.A N LEU 343.A O no hydrogen 2.612 N/A TYR 48.A N GLU 79.A O no hydrogen 3.221 N/A TYR 48.A OH THR 165.A OG1 no hydrogen 3.240 N/A TYR 48.A OH HIS 178.A ND1 no hydrogen 2.898 N/A LYS 49.A N ARG 341.A O no hydrogen 3.151 N/A LYS 49.A NZ VAL 335.A O no hydrogen 3.379 N/A LYS 49.A NZ GLY 337.A O no hydrogen 3.423 N/A ALA 50.A N ILE 77.A O no hydrogen 2.786 N/A GLY 51.A N ILE 77.A O no hydrogen 3.321 N/A THR 53.A N VAL 75.A O no hydrogen 2.846 N/A ILE 55.A N GLU 73.A O no hydrogen 3.262 N/A VAL 56.A N PHE 365.A O no hydrogen 2.961 N/A ARG 57.A N VAL 71.A O no hydrogen 3.311 N/A ARG 57.A NE GLU 73.A OE1 no hydrogen 3.414 N/A ARG 57.A NH1 GLU 359.A OE2 no hydrogen 3.492 N/A ARG 57.A NH2 GLU 359.A OE2 no hydrogen 3.563 N/A VAL 59.A N LYS 69.A O no hydrogen 2.917 N/A ARG 61.A N ASN 67.A OD1 no hydrogen 2.674 N/A SER 64.A N ARG 61.A O no hydrogen 3.326 N/A VAL 66.A N SER 64.A OG no hydrogen 3.424 N/A LYS 68.A N VAL 59.A O no hydrogen 2.685 N/A LYS 68.A NZ ASP 60.A OD2 no hydrogen 3.465 N/A LYS 69.A NZ ASN 67.A O no hydrogen 3.113 N/A VAL 71.A N ARG 57.A O no hydrogen 2.965 N/A VAL 75.A N THR 53.A O no hydrogen 2.904 N/A THR 76.A N LEU 331.A O no hydrogen 2.821 N/A THR 76.A OG1 GLY 333.A O no hydrogen 2.487 N/A ILE 77.A N GLY 51.A O no hydrogen 2.775 N/A VAL 78.A N VAL 329.A O no hydrogen 3.018 N/A GLU 79.A N TYR 48.A O no hydrogen 2.848 N/A THR 80.A N ASP 327.A O no hydrogen 2.752 N/A THR 80.A OG1 ASP 327.A O no hydrogen 3.227 N/A VAL 84.A N HIS 164.A O no hydrogen 2.892 N/A VAL 85.A N GLN 202.A O no hydrogen 3.201 N/A VAL 86.A N ILE 162.A O no hydrogen 2.835 N/A GLY 87.A N ILE 162.A O no hydrogen 3.354 N/A ILE 88.A N VAL 104.A O no hydrogen 2.801 N/A VAL 89.A N ARG 160.A O no hydrogen 2.764 N/A GLY 90.A N LYS 102.A O no hydrogen 3.035 N/A TYR 91.A N VAL 158.A O no hydrogen 3.113 N/A TYR 91.A OH GLU 181.A OE2 no hydrogen 2.822 N/A VAL 92.A N ARG 99.A O no hydrogen 2.761 N/A GLU 93.A N GLN 157.A OE1 no hydrogen 2.634 N/A THR 94.A N GLY 97.A O no hydrogen 3.320 N/A THR 94.A OG1 GLY 97.A O no hydrogen 2.274 N/A GLY 97.A N THR 94.A O no hydrogen 3.015 N/A ARG 99.A N VAL 92.A O no hydrogen 3.060 N/A PHE 101.A N GLY 90.A O no hydrogen 2.717 N/A THR 103.A OG1 ILE 88.A O no hydrogen 3.520 N/A VAL 104.A N ILE 88.A O no hydrogen 2.799 N/A PHE 105.A N TYR 132.A OH no hydrogen 2.694 N/A ALA 106.A N VAL 86.A O no hydrogen 2.497 N/A LYS 114.A N SER 110.A O no hydrogen 3.024 N/A LYS 114.A NZ ALA 128.A O no hydrogen 3.393 N/A ARG 115.A N ASP 111.A O no hydrogen 3.080 N/A ARG 115.A N GLU 112.A O no hydrogen 3.245 N/A ARG 116.A N CYS 113.A O no hydrogen 3.059 N/A ARG 116.A NE ALA 177.A O no hydrogen 2.801 N/A ARG 116.A NH2 ALA 177.A O no hydrogen 2.892 N/A PHE 117.A N LYS 114.A O no hydrogen 3.351 N/A TYR 118.A N ARG 115.A O no hydrogen 2.957 N/A SER 124.A OG TRP 121.A O no hydrogen 3.264 N/A LYS 126.A NZ SER 124.A O no hydrogen 3.342 N/A THR 130.A N LYS 127.A O no hydrogen 3.317 N/A THR 130.A OG1 LYS 127.A O no hydrogen 2.787 N/A TYR 132.A OH PHE 105.A O no hydrogen 3.117 N/A CYS 133.A SG THR 130.A O no hydrogen 3.608 N/A LYS 134.A N LYS 131.A O no hydrogen 3.384 N/A LYS 135.A N TYR 132.A O no hydrogen 3.036 N/A GLN 137.A NE2 GLU 107.A OE2 no hydrogen 2.422 N/A ASP 138.A N LYS 134.A O no hydrogen 3.274 N/A GLU 139.A N GLU 139.A OE1 no hydrogen 2.668 N/A LYS 142.A N ASP 138.A O no hydrogen 2.998 N/A LYS 142.A NZ TRP 136.A O no hydrogen 3.113 N/A LYS 143.A N GLU 139.A O no hydrogen 3.158 N/A GLN 144.A N ASP 140.A O no hydrogen 3.144 N/A LEU 145.A N GLY 141.A O no hydrogen 2.824 N/A GLU 146.A N LYS 142.A O no hydrogen 2.806 N/A LYS 147.A N LYS 143.A O no hydrogen 2.974 N/A ASP 148.A N GLN 144.A O no hydrogen 3.070 N/A PHE 149.A N LEU 145.A O no hydrogen 3.162 N/A SER 150.A N GLU 146.A O no hydrogen 3.091 N/A SER 150.A OG LYS 147.A O no hydrogen 2.701 N/A SER 151.A N LYS 147.A O no hydrogen 2.874 N/A SER 151.A OG LYS 147.A O no hydrogen 2.902 N/A MET 152.A N ASP 148.A O no hydrogen 2.938 N/A LYS 153.A N PHE 149.A O no hydrogen 2.982 N/A LYS 154.A N SER 151.A O no hydrogen 3.167 N/A TYR 155.A N SER 151.A O no hydrogen 3.112 N/A CYS 156.A N MET 152.A O no hydrogen 3.352 N/A GLN 157.A N TYR 91.A O no hydrogen 2.893 N/A GLN 157.A NE2 TYR 155.A O no hydrogen 3.557 N/A ARG 160.A N VAL 89.A O no hydrogen 2.836 N/A ARG 160.A NE GLN 183.A OE1 no hydrogen 3.332 N/A ARG 160.A NH1 GLU 181.A OE2 no hydrogen 3.083 N/A VAL 161.A N ILE 182.A O no hydrogen 2.761 N/A ILE 162.A N GLY 87.A O no hydrogen 2.670 N/A ALA 163.A N MET 180.A O no hydrogen 2.623 N/A HIS 164.A N VAL 84.A O no hydrogen 2.857 N/A HIS 164.A ND1 THR 165.A O no hydrogen 2.763 N/A THR 165.A N HIS 178.A O no hydrogen 3.235 N/A THR 165.A OG1 TYR 48.A OH no hydrogen 3.240 N/A MET 167.A N GLU 112.A OE1 no hydrogen 3.152 N/A LEU 170.A N MET 167.A O no hydrogen 3.172 N/A GLN 174.A NE2 LYS 176.A O no hydrogen 2.727 N/A LYS 176.A NZ TYR 118.A O no hydrogen 3.013 N/A ALA 177.A N GLU 112.A O no hydrogen 3.404 N/A HIS 178.A ND1 TYR 48.A OH no hydrogen 2.898 N/A MET 180.A N ALA 163.A O no hydrogen 2.916 N/A ILE 182.A N VAL 161.A O no hydrogen 2.708 N/A GLN 183.A NE2 ASN 185.A OD1 no hydrogen 2.815 N/A VAL 184.A N ILE 159.A O no hydrogen 3.093 N/A ASN 185.A N HIS 41.A O no hydrogen 3.043 N/A ASN 185.A ND2 PRO 32.A O no hydrogen 3.160 N/A GLY 186.A N ASP 34.A OD1 no hydrogen 3.020 N/A GLY 187.A N PRO 36.A O no hydrogen 2.976 N/A THR 188.A OG1 GLU 191.A OE2 no hydrogen 3.223 N/A GLU 191.A N THR 188.A OG1 no hydrogen 3.429 N/A LYS 192.A N THR 188.A O no hydrogen 3.042 N/A LYS 192.A NZ ASP 34.A OD2 no hydrogen 2.679 N/A LYS 192.A NZ VAL 184.A O no hydrogen 3.396 N/A LEU 193.A N VAL 189.A O no hydrogen 3.260 N/A ASP 194.A N ALA 190.A O no hydrogen 3.207 N/A TRP 195.A N GLU 191.A O no hydrogen 2.735 N/A ALA 196.A N LYS 192.A O no hydrogen 2.671 N/A ARG 197.A N LEU 193.A O no hydrogen 2.763 N/A ARG 197.A NH1 GLU 146.A OE2 no hydrogen 3.418 N/A ARG 197.A NH2 GLU 146.A OE1 no hydrogen 3.136 N/A GLU 198.A N ASP 194.A O no hydrogen 3.206 N/A ARG 199.A N TRP 195.A O no hydrogen 3.472 N/A LEU 200.A N ARG 197.A O no hydrogen 3.279 N/A GLU 201.A N VAL 85.A O no hydrogen 2.869 N/A GLN 202.A N ARG 199.A O no hydrogen 2.929 N/A VAL 204.A N MET 83.A O no hydrogen 3.000 N/A GLN 208.A N PRO 205.A O no hydrogen 3.282 N/A VAL 209.A N VAL 206.A O no hydrogen 3.043 N/A PHE 210.A N VAL 206.A O no hydrogen 3.120 N/A GLY 211.A N GLU 214.A OE1 no hydrogen 3.246 N/A GLN 212.A NE2 TYR 283.A O no hydrogen 2.354 N/A ASP 213.A N ILE 282.A O no hydrogen 2.961 N/A GLU 214.A N GLY 211.A O no hydrogen 3.439 N/A ILE 216.A N LYS 280.A O no hydrogen 2.862 N/A ASP 217.A N ARG 346.A O no hydrogen 2.715 N/A VAL 218.A N GLU 277.A O no hydrogen 2.856 N/A ILE 219.A N THR 344.A O no hydrogen 2.879 N/A GLY 220.A N ARG 275.A O no hydrogen 3.352 N/A THR 222.A N HIS 273.A O no hydrogen 3.020 N/A THR 222.A OG1 HIS 273.A O no hydrogen 3.454 N/A LYS 225.A N LYS 270.A O no hydrogen 2.999 N/A LYS 228.A N GLY 268.A O no hydrogen 2.930 N/A ARG 233.A N GLY 229.A O no hydrogen 2.642 N/A ARG 233.A NE GLN 269.A O no hydrogen 2.683 N/A ARG 233.A NH1 ARG 266.A O no hydrogen 3.190 N/A ARG 233.A NH2 ARG 18.A O no hydrogen 3.373 N/A ARG 233.A NH2 GLN 269.A O no hydrogen 3.051 N/A TRP 234.A N VAL 230.A O no hydrogen 2.812 N/A LEU 239.A N LEU 246.A O no hydrogen 3.051 N/A THR 243.A OG1 PRO 240.A O no hydrogen 3.014 N/A LYS 248.A NZ ARG 244.A O no hydrogen 2.736 N/A CYS 251.A SG GLY 253.A O no hydrogen 3.051 N/A ARG 259.A N PRO 257.A O no hydrogen 2.758 N/A VAL 264.A N ALA 261.A O no hydrogen 3.421 N/A GLY 268.A N LYS 228.A O no hydrogen 2.942 N/A GLN 269.A NE2 LYS 270.A O no hydrogen 3.035 N/A GLN 269.A NE2 GLY 271.A O no hydrogen 3.472 N/A LYS 270.A N GLY 226.A O no hydrogen 3.000 N/A LYS 270.A NZ SER 232.A O no hydrogen 2.849 N/A TYR 272.A N LYS 223.A O no hydrogen 3.002 N/A TYR 272.A OH HIS 24.A ND1 no hydrogen 2.758 N/A HIS 273.A N THR 222.A OG1 no hydrogen 3.024 N/A HIS 273.A ND1 LYS 19.A O no hydrogen 2.654 N/A ARG 275.A N GLY 220.A O no hydrogen 3.283 N/A ARG 275.A NH1 HIS 274.A O no hydrogen 2.805 N/A GLU 277.A N VAL 218.A O no hydrogen 2.946 N/A LYS 280.A N ILE 216.A O no hydrogen 2.953 N/A LYS 280.A NZ CYS 334.A O no hydrogen 3.356 N/A LYS 281.A NZ ASP 213.A O no hydrogen 2.935 N/A LYS 281.A NZ ARG 356.A O no hydrogen 3.207 N/A LYS 281.A NZ GLU 359.A O no hydrogen 3.361 N/A ILE 282.A N GLU 214.A O no hydrogen 3.118 N/A TYR 283.A N MET 330.A O no hydrogen 2.947 N/A TYR 283.A OH GLU 73.A OE1 no hydrogen 2.209 N/A LYS 284.A NZ ASN 300.A O no hydrogen 3.402 N/A GLY 286.A N PHE 328.A O no hydrogen 2.717 N/A TYR 289.A OH SER 311.A OG no hydrogen 2.907 N/A LYS 292.A N LYS 295.A O no hydrogen 3.293 N/A ILE 297.A N LEU 290.A O no hydrogen 3.141 N/A ALA 301.A N LYS 310.A O no hydrogen 3.007 N/A SER 302.A OG ASN 299.A O no hydrogen 3.054 N/A THR 303.A OG1 LYS 364.A O no hydrogen 2.493 N/A ASP 306.A N THR 303.A OG1 no hydrogen 3.004 N/A LYS 310.A NZ ILE 366.A O no hydrogen 3.022 N/A LYS 310.A NZ THR 368.A OG1 no hydrogen 2.982 N/A LYS 310.A NZ GLN 378.A OE1 no hydrogen 2.749 N/A SER 311.A OG TYR 289.A OH no hydrogen 2.907 N/A ASN 313.A N SER 311.A OG no hydrogen 3.243 N/A ASN 313.A ND2 SER 311.A OG no hydrogen 3.280 N/A ASN 313.A ND2 VAL 324.A O no hydrogen 3.008 N/A LEU 315.A N THR 368.A O no hydrogen 3.259 N/A GLY 317.A N PRO 314.A O no hydrogen 2.698 N/A PHE 318.A N GLY 322.A O no hydrogen 2.798 N/A TYR 321.A N PHE 318.A O no hydrogen 3.290 N/A TYR 321.A OH GLU 79.A OE1 no hydrogen 2.245 N/A GLY 322.A N PHE 318.A O no hydrogen 3.124 N/A VAL 324.A N ASN 313.A OD1 no hydrogen 2.765 N/A THR 325.A N GLU 79.A OE2 no hydrogen 3.388 N/A ASN 326.A ND2 GLU 79.A OE2 no hydrogen 3.101 N/A ASN 326.A ND2 LEU 169.A O no hydrogen 3.340 N/A VAL 329.A N VAL 78.A O no hydrogen 2.816 N/A MET 330.A N LYS 284.A O no hydrogen 2.934 N/A LEU 331.A N THR 76.A O no hydrogen 2.988 N/A LYS 332.A N LYS 281.A O no hydrogen 3.151 N/A LYS 332.A NZ GLU 73.A OE2 no hydrogen 3.301 N/A GLY 333.A N ALA 74.A O no hydrogen 2.775 N/A ARG 341.A N THR 338.A O no hydrogen 3.468 N/A ARG 341.A NH1 THR 222.A O no hydrogen 3.085 N/A LEU 343.A N GLY 47.A O no hydrogen 2.557 N/A THR 344.A N ILE 219.A O no hydrogen 3.008 N/A THR 344.A OG1 ARG 25.A O no hydrogen 3.391 N/A THR 344.A OG1 GLY 26.A O no hydrogen 3.080 N/A LEU 345.A N PHE 45.A O no hydrogen 2.825 N/A ARG 346.A N ASP 217.A O no hydrogen 2.799 N/A ARG 346.A NE ASP 217.A OD2 no hydrogen 3.383 N/A ARG 346.A NH2 ASP 217.A OD2 no hydrogen 2.594 N/A LYS 347.A N THR 43.A O no hydrogen 3.101 N/A LYS 347.A NZ VAL 209.A O no hydrogen 3.464 N/A LYS 347.A NZ GLU 214.A OE1 no hydrogen 3.280 N/A LYS 347.A NZ GLU 214.A OE2 no hydrogen 2.543 N/A SER 348.A OG MET 215.A O no hydrogen 2.621 N/A GLN 352.A NE2 LEU 350.A O no hydrogen 3.548 N/A ILE 361.A N ASP 213.A OD1 no hydrogen 3.233 N/A LYS 364.A N VAL 56.A O no hydrogen 2.882 N/A LYS 364.A NZ GLU 70.A OE2 no hydrogen 2.484 N/A PHE 365.A N VAL 56.A O no hydrogen 3.405 N/A ASP 367.A N HIS 54.A O no hydrogen 3.068 N/A THR 368.A N GLN 378.A OE1 no hydrogen 2.714 N/A THR 368.A OG1 ILE 366.A O no hydrogen 3.537 N/A THR 369.A OG1 ASP 367.A OD1 no hydrogen 3.058 N/A THR 369.A OG1 ASP 367.A OD2 no hydrogen 2.813 N/A SER 370.A OG LEU 315.A O no hydrogen 3.334 N/A LYS 371.A NZ ASP 367.A OD2 no hydrogen 2.499 N/A PHE 372.A N SER 370.A OG no hydrogen 3.247 N/A GLN 378.A N GLU 382.A OE1 no hydrogen 3.247 N/A GLN 378.A NE2 ASP 367.A OD1 no hydrogen 2.669 N/A GLU 382.A N THR 379.A OG1 no hydrogen 3.320 N/A LYS 383.A N THR 379.A O no hydrogen 3.255 N/A LYS 384.A N MET 380.A O no hydrogen 3.248 N/A ALA 385.A N GLU 381.A O no hydrogen 3.165 N/A PHE 386.A N GLU 382.A O no hydrogen 3.096 N/A MET 387.A N LYS 383.A O no hydrogen 2.863 N/A GLY 388.A N LYS 384.A O no hydrogen 2.812 N/A LEU 390.A N ASP 393.A OD2 no hydrogen 2.880 N/A ASP 393.A N LEU 390.A O no hydrogen 2.933 N/A ARG 394.A N LEU 390.A O no hydrogen 3.361 N/A ILE 395.A N LYS 391.A O no hydrogen 3.091 N/A ALA 396.A N LYS 392.A O no hydrogen 3.068 N/A LYS 397.A N ASP 393.A O no hydrogen 3.154 N/A GLU 398.A N ARG 394.A O no hydrogen 3.156 N/A GLU 399.A N ILE 395.A O no hydrogen 2.872 N/A GLY 400.A N ALA 396.A O no hydrogen 2.843 N/A ALA 401.A N LYS 397.A O no hydrogen 2.615 N/A