Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8fll_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 3.A N VAL 69.A O no hydrogen 2.840 N/A LYS 6.A N ASP 4.A OD1 no hydrogen 3.037 N/A ASP 7.A N ASP 4.A O no hydrogen 2.857 N/A LEU 8.A N PRO 5.A O no hydrogen 3.022 N/A THR 9.A N LYS 26.A O no hydrogen 2.944 N/A LEU 11.A N TYR 24.A O no hydrogen 2.796 N/A LYS 12.A N TYR 24.A O no hydrogen 3.292 N/A LEU 14.A N VAL 22.A O no hydrogen 2.871 N/A THR 16.A OG1 GLU 13.A OE2.B no hydrogen 3.064 N/A GLY 17.A N GLY 20.A O no hydrogen 3.246 N/A GLY 20.A N GLY 17.A O no hydrogen 3.164 N/A VAL 22.A N GLY 15.A O no hydrogen 2.894 N/A LYS 23.A N ILE 35.A O no hydrogen 2.864 N/A LYS 23.A NZ GLU 13.A OE2.A no hydrogen 2.986 N/A TYR 24.A N LYS 12.A O no hydrogen 2.812 N/A TYR 24.A OH ASP 32.A OD1 no hydrogen 2.613 N/A GLY 25.A N VAL 33.A O no hydrogen 2.928 N/A LYS 26.A N THR 9.A O no hydrogen 2.936 N/A LYS 26.A NZ TYR 24.A OH no hydrogen 3.436 N/A LYS 26.A NZ ASP 32.A OD1 no hydrogen 2.692 N/A TRP 27.A N TYR 31.A O no hydrogen 2.802 N/A ARG 28.A N ASP 7.A O no hydrogen 2.800 N/A ARG 28.A NH2 ASP 7.A OD2 no hydrogen 3.508 N/A GLN 30.A N TRP 27.A O no hydrogen 3.133 N/A TYR 31.A N TRP 27.A O no hydrogen 3.029 N/A VAL 33.A N GLY 25.A O no hydrogen 2.892 N/A ALA 34.A N THR 80.A O no hydrogen 2.871 N/A ILE 35.A N LYS 23.A O no hydrogen 2.789 N/A LYS 36.A N ILE 78.A O no hydrogen 2.837 N/A MET 37.A N VAL 21.A O no hydrogen 2.864 N/A ILE 38.A N ILE 76.A O no hydrogen 2.897 N/A LYS 39.A N PHE 19.A O no hydrogen 2.913 N/A SER 42.A N LYS 39.A O no hydrogen 3.103 N/A SER 42.A OG LYS 39.A O no hydrogen 2.714 N/A SER 44.A N.A TYR 151.A O no hydrogen 2.812 N/A SER 44.A N.B TYR 151.A O no hydrogen 2.807 N/A SER 44.A OG.B GLU 47.A OE1 no hydrogen 2.939 N/A PHE 48.A N SER 44.A O.A no hydrogen 2.949 N/A PHE 48.A N SER 44.A O.B no hydrogen 2.998 N/A ILE 49.A N GLU 45.A O no hydrogen 2.907 N/A GLU 50.A N ASP 46.A O no hydrogen 3.089 N/A GLU 51.A N GLU 47.A O no hydrogen 3.198 N/A ALA 52.A N ILE 49.A O no hydrogen 3.300 N/A VAL 54.A N GLU 51.A O no hydrogen 2.974 N/A MET 55.A N GLU 51.A O no hydrogen 3.486 N/A MET 56.A N ALA 52.A O no hydrogen 2.873 N/A ASN 57.A N LYS 53.A O no hydrogen 3.005 N/A ASN 57.A N VAL 54.A O no hydrogen 3.147 N/A LEU 58.A N MET 55.A O no hydrogen 3.133 N/A SER 59.A N TYR 117.A OH no hydrogen 3.061 N/A LYS 62.A N HIS 60.A ND1 no hydrogen 2.910 N/A LYS 62.A NZ ASP 110.A OD1 no hydrogen 2.748 N/A LYS 62.A NZ GLU 113.A OE1 no hydrogen 2.714 N/A LEU 63.A N HIS 60.A O no hydrogen 2.994 N/A VAL 64.A N VAL 143.A O no hydrogen 2.883 N/A GLN 65.A N GLU 81.A OE1 no hydrogen 2.955 N/A GLN 65.A NE2 LEU 58.A O no hydrogen 3.345 N/A GLN 65.A NE2 LEU 63.A O no hydrogen 3.013 N/A TYR 67.A N ILE 79.A O.A no hydrogen 2.821 N/A TYR 67.A N ILE 79.A O.B no hydrogen 2.857 N/A GLY 68.A N ILE 79.A O.A no hydrogen 3.345 N/A GLY 68.A N ILE 79.A O.B no hydrogen 3.367 N/A VAL 69.A N TRP 1.A O no hydrogen 2.832 N/A CYS 70.A N PHE 77.A O no hydrogen 2.873 N/A CYS 70.A SG ILE 3.A O no hydrogen 3.372 N/A THR 71.A N GLU 2.A OE1 no hydrogen 2.790 N/A THR 71.A OG1 GLU 2.A OE1 no hydrogen 3.414 N/A THR 71.A OG1 GLU 2.A OE2 no hydrogen 2.773 N/A GLN 73.A NE2 CYS 70.A O no hydrogen 3.263 N/A GLN 73.A NE2 PRO 75.A O no hydrogen 2.811 N/A PHE 77.A N CYS 70.A O no hydrogen 3.092 N/A ILE 78.A N LYS 36.A O no hydrogen 2.868 N/A ILE 79.A N.A GLY 68.A O no hydrogen 2.881 N/A ILE 79.A N.B GLY 68.A O no hydrogen 2.893 N/A THR 80.A N ALA 34.A O no hydrogen 2.900 N/A THR 80.A OG1 GLU 81.A O no hydrogen 2.934 N/A GLU 81.A N GLN 65.A O no hydrogen 2.934 N/A ASN 85.A N VAL 135.A O no hydrogen 2.850 N/A ASN 85.A ND2 ASN 136.A O no hydrogen 3.049 N/A GLY 86.A N MET 83.A O no hydrogen 3.088 N/A LEU 88.A N CYS 133.A O no hydrogen 2.877 N/A TYR 91.A N CYS 87.A O no hydrogen 3.044 N/A LEU 92.A N LEU 88.A O no hydrogen 2.833 N/A ARG 93.A N LEU 89.A O no hydrogen 3.348 N/A GLU 94.A N ASN 90.A O no hydrogen 3.046 N/A MET 95.A N TYR 91.A O no hydrogen 2.969 N/A ARG 96.A NE LEU 199.A O no hydrogen 2.828 N/A ARG 96.A NH2 LEU 199.A O no hydrogen 2.867 N/A ARG 98.A N MET 95.A O no hydrogen 2.929 N/A GLN 100.A N GLN 103.A OE1 no hydrogen 2.872 N/A GLN 103.A N GLN 100.A O no hydrogen 2.902 N/A LEU 104.A N THR 101.A O no hydrogen 2.951 N/A GLU 106.A N.A GLN 102.A O no hydrogen 3.203 N/A GLU 106.A N.B GLN 102.A O no hydrogen 3.202 N/A MET 107.A N GLN 103.A O no hydrogen 3.057 N/A CYS 108.A N LEU 104.A O no hydrogen 3.181 N/A CYS 108.A SG LEU 104.A O no hydrogen 3.551 N/A LYS 109.A N LEU 105.A O no hydrogen 2.929 N/A LYS 109.A NZ GLU 113.A OE2 no hydrogen 2.684 N/A ASP 110.A N GLU 106.A O.A no hydrogen 2.923 N/A ASP 110.A N GLU 106.A O.B no hydrogen 2.934 N/A VAL 111.A N MET 107.A O no hydrogen 3.126 N/A CYS 112.A N CYS 108.A O no hydrogen 2.875 N/A CYS 112.A SG PHE 250.A O no hydrogen 3.562 N/A GLU 113.A N LYS 109.A O no hydrogen 2.881 N/A ALA 114.A N ASP 110.A O no hydrogen 3.236 N/A MET 115.A N VAL 111.A O no hydrogen 2.990 N/A GLU 116.A N CYS 112.A O no hydrogen 2.815 N/A TYR 117.A N GLU 113.A O no hydrogen 3.118 N/A LEU 118.A N ALA 114.A O no hydrogen 2.959 N/A GLU 119.A N MET 115.A O no hydrogen 2.832 N/A SER 120.A N GLU 116.A O no hydrogen 2.965 N/A SER 120.A OG TYR 117.A O no hydrogen 2.693 N/A LYS 121.A N LEU 118.A O no hydrogen 2.916 N/A GLN 122.A N GLU 119.A O no hydrogen 2.958 N/A PHE 123.A N LEU 118.A O no hydrogen 3.007 N/A HIS 125.A N ASP 185.A OD2 no hydrogen 2.859 N/A HIS 125.A NE2 SER 144.A O no hydrogen 2.856 N/A ARG 126.A N ASP 185.A OD1 no hydrogen 3.044 N/A ASP 127.A N HIS 125.A ND1 no hydrogen 2.991 N/A ALA 130.A N GLU 195.A OE2 no hydrogen 2.910 N/A ARG 131.A NH2 ASP 127.A OD1 no hydrogen 2.866 N/A ASN 132.A N ALA 129.A O no hydrogen 2.915 N/A ASN 132.A ND2 ASP 127.A O no hydrogen 2.735 N/A CYS 133.A N ALA 130.A O no hydrogen 3.138 N/A CYS 133.A SG ALA 129.A O no hydrogen 3.635 N/A LEU 134.A N LYS 142.A O no hydrogen 2.912 N/A VAL 135.A N GLY 86.A O no hydrogen 2.839 N/A ASN 136.A N VAL 140.A O no hydrogen 2.952 N/A GLN 138.A N ASN 136.A OD1 no hydrogen 2.958 N/A GLY 139.A N ASN 136.A O no hydrogen 2.990 N/A VAL 140.A N ASN 136.A OD1 no hydrogen 2.963 N/A VAL 141.A N ASP 110.A OD2 no hydrogen 3.087 N/A LYS 142.A N LEU 134.A O no hydrogen 2.814 N/A LYS 142.A NZ GLU 61.A O no hydrogen 2.900 N/A LYS 142.A NZ GLU 81.A OE2 no hydrogen 2.729 N/A VAL 143.A N LYS 62.A O no hydrogen 2.902 N/A SER 144.A N ASN 132.A O no hydrogen 2.977 N/A SER 144.A OG ASP 145.A OD1 no hydrogen 3.226 N/A GLY 147.A N HIS 125.A O no hydrogen 2.998 N/A LEU 148.A N ASP 145.A O no hydrogen 3.191 N/A ARG 150.A N GLY 147.A O no hydrogen 3.437 N/A TYR 151.A N LEU 148.A O no hydrogen 2.874 N/A VAL 152.A N SER 149.A O no hydrogen 3.333 N/A LEU 153.A N SER 42.A O no hydrogen 3.228 N/A GLU 156.A N ASP 154.A OD1 no hydrogen 2.972 N/A TYR 157.A N ASP 154.A O no hydrogen 2.956 N/A TYR 157.A OH ASP 127.A OD2 no hydrogen 2.507 N/A THR 158.A N ASP 154.A O no hydrogen 3.364 N/A SER 159.A N ASP 155.A O no hydrogen 2.949 N/A SER 160.A OG VAL 174.A O no hydrogen 3.409 N/A SER 160.A OG SER 178.A OG no hydrogen 2.495 N/A VAL 161.A N SER 159.A OG no hydrogen 3.338 N/A GLY 162.A N SER 159.A O no hydrogen 2.828 N/A SER 163.A N.A GLU 156.A OE1 no hydrogen 2.819 N/A SER 163.A N.B GLU 156.A OE1 no hydrogen 2.821 N/A SER 163.A OG.A GLU 156.A OE1 no hydrogen 3.080 N/A SER 163.A OG.B GLU 156.A OE1 no hydrogen 3.504 N/A LYS 164.A N GLU 156.A O no hydrogen 2.922 N/A PHE 165.A N GLY 162.A O no hydrogen 3.273 N/A VAL 167.A N PHE 165.A O no hydrogen 2.760 N/A ARG 168.A NH1 PRO 203.A O no hydrogen 3.030 N/A ARG 168.A NH1 TYR 204.A O no hydrogen 2.892 N/A ARG 168.A NH1 PHE 207.A O no hydrogen 3.093 N/A ARG 168.A NH2 PHE 207.A O no hydrogen 2.886 N/A TRP 169.A N PRO 166.A O no hydrogen 2.972 N/A TRP 169.A NE1 GLU 195.A OE2 no hydrogen 2.891 N/A SER 170.A N VAL 167.A O no hydrogen 3.147 N/A SER 170.A OG PRO 166.A O no hydrogen 2.792 N/A GLU 173.A N GLU 173.A OE1 no hydrogen 2.841 N/A VAL 174.A N PRO 171.A O no hydrogen 3.084 N/A LEU 175.A N PRO 171.A O no hydrogen 3.137 N/A MET 176.A N PRO 172.A O no hydrogen 2.943 N/A TYR 177.A N GLU 173.A O no hydrogen 3.078 N/A SER 178.A N VAL 174.A O no hydrogen 2.892 N/A SER 178.A OG SER 160.A OG no hydrogen 2.495 N/A LYS 179.A N GLU 173.A O no hydrogen 3.063 N/A SER 181.A N SER 184.A OG no hydrogen 2.961 N/A LYS 183.A N SER 181.A OG no hydrogen 3.022 N/A LYS 183.A NZ ARG 247.A O no hydrogen 2.979 N/A LYS 183.A NZ PRO 248.A O no hydrogen 3.106 N/A SER 184.A N SER 181.A O no hydrogen 3.000 N/A SER 184.A OG SER 181.A O no hydrogen 2.928 N/A ASP 185.A N SER 181.A O no hydrogen 3.356 N/A ILE 186.A N SER 182.A O no hydrogen 2.962 N/A TRP 187.A N LYS 183.A O no hydrogen 3.148 N/A ALA 188.A N SER 184.A O no hydrogen 3.110 N/A PHE 189.A N ASP 185.A O no hydrogen 2.873 N/A GLY 190.A N ILE 186.A O no hydrogen 3.068 N/A VAL 191.A N TRP 187.A O no hydrogen 3.134 N/A LEU 192.A N ALA 188.A O no hydrogen 2.830 N/A MET 193.A N PHE 189.A O no hydrogen 2.843 N/A TRP 194.A N GLY 190.A O no hydrogen 3.030 N/A TRP 194.A NE1 TYR 223.A O.A no hydrogen 2.871 N/A TRP 194.A NE1 TYR 223.A O.B no hydrogen 2.858 N/A GLU 195.A N VAL 191.A O no hydrogen 2.869 N/A ILE 196.A N LEU 192.A O no hydrogen 2.887 N/A TYR 197.A N MET 193.A O no hydrogen 2.891 N/A SER 198.A N.A TRP 194.A O no hydrogen 2.868 N/A SER 198.A N.B TRP 194.A O no hydrogen 2.881 N/A SER 198.A OG.A TRP 194.A O no hydrogen 2.754 N/A SER 198.A OG.B TRP 194.A O no hydrogen 3.079 N/A SER 198.A OG.B GLU 195.A O no hydrogen 3.116 N/A LEU 199.A N ILE 196.A O no hydrogen 3.011 N/A GLY 200.A N GLU 195.A O no hydrogen 2.845 N/A LYS 201.A N SER 198.A O.A no hydrogen 3.342 N/A LYS 201.A N SER 198.A OG.B no hydrogen 3.181 N/A PHE 207.A N TYR 204.A O no hydrogen 2.877 N/A THR 208.A N GLU 211.A OE1 no hydrogen 2.908 N/A THR 208.A OG1 SER 210.A OG.A no hydrogen 3.185 N/A SER 210.A OG.A THR 208.A OG1 no hydrogen 3.185 N/A GLU 211.A N THR 208.A OG1 no hydrogen 3.111 N/A THR 212.A N THR 208.A O no hydrogen 2.765 N/A THR 212.A OG1 THR 208.A O no hydrogen 2.819 N/A ALA 213.A N ASN 209.A O no hydrogen 2.920 N/A GLU 214.A N SER 210.A O.A no hydrogen 3.127 N/A GLU 214.A N SER 210.A O.B no hydrogen 3.214 N/A HIS 215.A N GLU 211.A O no hydrogen 2.815 N/A ILE 216.A N THR 212.A O no hydrogen 2.895 N/A ALA 217.A N ALA 213.A O no hydrogen 3.019 N/A GLN 218.A N GLU 214.A O no hydrogen 2.887 N/A GLY 219.A N ILE 216.A O no hydrogen 2.933 N/A LEU 220.A N HIS 215.A O no hydrogen 3.061 N/A ARG 221.A NE TRP 240.A O no hydrogen 2.987 N/A ARG 221.A NH1 ILE 216.A O no hydrogen 3.018 N/A ARG 221.A NH1 LEU 220.A O no hydrogen 2.935 N/A ARG 221.A NH2 TRP 240.A O no hydrogen 3.055 N/A ARG 224.A NH2 ALA 228.A O no hydrogen 2.933 N/A ALA 228.A N PRO 225.A O no hydrogen 2.948 N/A VAL 232.A N SER 229.A OG no hydrogen 3.157 N/A TYR 233.A N SER 229.A O no hydrogen 2.879 N/A TYR 233.A OH LEU 222.A O no hydrogen 2.637 N/A THR 234.A N GLU 230.A O no hydrogen 2.879 N/A THR 234.A OG1 GLU 230.A O no hydrogen 2.905 N/A ILE 235.A N LYS 231.A O no hydrogen 3.311 N/A MET 236.A N VAL 232.A O no hydrogen 3.095 N/A TYR 237.A N TYR 233.A O no hydrogen 2.807 N/A SER 238.A N THR 234.A O no hydrogen 2.993 N/A SER 238.A OG ILE 235.A O no hydrogen 2.625 N/A CYS 239.A N MET 236.A O no hydrogen 3.052 N/A CYS 239.A SG ILE 235.A O no hydrogen 3.760 N/A TRP 240.A N TYR 237.A O no hydrogen 2.958 N/A GLU 246.A N LYS 243.A O no hydrogen 2.942 N/A ARG 247.A N ALA 244.A O no hydrogen 3.124 N/A ARG 247.A NE HIS 241.A O no hydrogen 2.820 N/A ARG 247.A NH1 GLU 173.A OE2 no hydrogen 2.796 N/A ARG 247.A NH1 LYS 183.A O no hydrogen 3.025 N/A ARG 247.A NH2 GLU 173.A OE1 no hydrogen 2.833 N/A ARG 247.A NH2 HIS 241.A O no hydrogen 3.089 N/A ARG 247.A NH2 GLU 242.A O.A no hydrogen 3.111 N/A ARG 247.A NH2 GLU 242.A O.B no hydrogen 3.138 N/A PHE 250.A N GLU 119.A OE2 no hydrogen 2.837 N/A ILE 252.A N THR 249.A OG1 no hydrogen 3.103 N/A LEU 253.A N THR 249.A O no hydrogen 2.955 N/A LEU 254.A N PHE 250.A O no hydrogen 2.888 N/A SER 255.A N LYS 251.A O no hydrogen 3.142 N/A SER 255.A OG LYS 251.A O no hydrogen 3.263 N/A ASN 256.A N ILE 252.A O no hydrogen 2.958 N/A ILE 257.A N LEU 253.A O no hydrogen 2.856 N/A LEU 258.A N LEU 254.A O no hydrogen 2.911 N/A ASP 259.A N SER 255.A O no hydrogen 2.930 N/A VAL 260.A N ASN 256.A O no hydrogen 3.087 N/A MET 261.A N ILE 257.A O no hydrogen 2.933 N/A ASP 262.A N LEU 258.A O no hydrogen 2.912 N/A GLU 263.A N ASP 259.A O no hydrogen 2.996 N/A GLU 263.A N VAL 260.A O no hydrogen 3.186 N/A GLU 264.A N VAL 260.A O no hydrogen 2.783 N/A