Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8flq_R.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 6.A N THR 3.A OG1 no hydrogen 3.114 N/A GLN 7.A N THR 3.A O no hydrogen 3.166 N/A GLN 7.A NE2 GLN 7.A O no hydrogen 3.329 N/A GLN 7.A NE2 TYR 53.A O no hydrogen 2.447 N/A ILE 8.A N LYS 4.A O no hydrogen 2.909 N/A PHE 9.A N GLU 5.A O no hydrogen 2.888 N/A LEU 10.A N GLU 6.A O no hydrogen 2.900 N/A LEU 11.A N GLN 7.A O no hydrogen 2.882 N/A HIS 12.A N ILE 8.A O no hydrogen 2.898 N/A ARG 13.A N PHE 9.A O no hydrogen 2.892 N/A ALA 14.A N LEU 10.A O no hydrogen 2.905 N/A GLN 15.A N LEU 11.A O no hydrogen 2.879 N/A ALA 16.A N HIS 12.A O no hydrogen 2.896 N/A GLN 17.A N ARG 13.A O no hydrogen 2.914 N/A CYS 18.A N ALA 14.A O no hydrogen 2.899 N/A GLU 19.A N GLN 15.A O no hydrogen 2.886 N/A LYS 20.A N ALA 16.A O no hydrogen 2.905 N/A ARG 21.A N GLN 17.A O no hydrogen 2.908 N/A LEU 22.A N CYS 18.A O no hydrogen 2.894 N/A LYS 23.A N GLU 19.A O no hydrogen 3.164 N/A ARG 25.A N ARG 69.A O no hydrogen 3.142 N/A CYS 27.A N GLY 40.A O no hydrogen 3.345 N/A TRP 31.A NE1 GLN 15.A OE1 no hydrogen 2.908 N/A ILE 34.A N ASP 32.A OD1 no hydrogen 3.169 N/A LEU 35.A N ASP 32.A OD1 no hydrogen 2.839 N/A TRP 37.A N GLU 30.A O no hydrogen 3.434 N/A TRP 37.A NE1 ASP 32.A OD2 no hydrogen 3.097 N/A GLY 40.A N CYS 27.A O no hydrogen 3.435 N/A GLY 43.A N ASP 68.A O no hydrogen 2.889 N/A VAL 46.A N ARG 65.A O no hydrogen 2.891 N/A VAL 48.A N ALA 63.A O no hydrogen 2.901 N/A CYS 50.A N GLY 61.A O no hydrogen 3.138 N/A CYS 50.A SG ASN 58.A O no hydrogen 3.185 N/A TYR 53.A OH ILE 34.A O no hydrogen 2.793 N/A ASN 58.A N CYS 89.A O no hydrogen 3.209 N/A HIS 59.A NE2 ILE 54.A O no hydrogen 3.110 N/A GLY 61.A N ASN 58.A O no hydrogen 2.941 N/A ALA 63.A N VAL 48.A O no hydrogen 2.886 N/A TYR 64.A N ASN 85.A O no hydrogen 3.412 N/A ARG 65.A N VAL 46.A O no hydrogen 2.907 N/A ARG 65.A NH1 ASP 32.A OD2 no hydrogen 2.931 N/A ARG 65.A NH2 ASP 32.A OD2 no hydrogen 2.431 N/A CYS 67.A SG ALA 41.A O no hydrogen 3.722 N/A CYS 67.A SG ASP 68.A O no hydrogen 3.156 N/A ASP 68.A N SER 72.A O no hydrogen 3.062 N/A TRP 73.A NE1 LEU 28.A O no hydrogen 2.581 N/A GLU 74.A N ARG 66.A O no hydrogen 3.040 N/A VAL 76.A N ARG 81.A O no hydrogen 2.542 N/A HIS 79.A N VAL 76.A O no hydrogen 3.143 N/A TRP 83.A N GLU 74.A O no hydrogen 2.488 N/A TYR 86.A OH ASP 32.A OD2 no hydrogen 2.497 N/A SER 87.A OG ASN 85.A OD1 no hydrogen 3.230 N/A CYS 89.A N TYR 86.A O no hydrogen 3.298 N/A VAL 90.A N SER 87.A O no hydrogen 2.919 N/A LEU 93.A N VAL 90.A O no hydrogen 3.350 N/A ARG 98.A NH1 GLU 101.A OE1 no hydrogen 2.835 N/A GLU 101.A N THR 97.A O no hydrogen 2.896 N/A VAL 102.A N ARG 98.A O no hydrogen 2.885 N/A PHE 103.A N GLU 99.A O no hydrogen 2.937 N/A ASP 104.A N ARG 100.A O no hydrogen 2.876 N/A ARG 105.A N GLU 101.A O no hydrogen 2.876 N/A LEU 106.A N VAL 102.A O no hydrogen 2.928 N/A GLY 107.A N PHE 103.A O no hydrogen 2.908 N/A MET 108.A N ASP 104.A O no hydrogen 2.896 N/A ILE 109.A N ARG 105.A O no hydrogen 2.955 N/A TYR 110.A N LEU 106.A O no hydrogen 2.985 N/A TYR 110.A OH ASP 160.A OD2 no hydrogen 3.029 N/A THR 111.A N GLY 107.A O no hydrogen 2.891 N/A THR 111.A OG1 GLY 107.A O no hydrogen 2.729 N/A VAL 112.A N MET 108.A O no hydrogen 2.941 N/A GLY 113.A N ILE 109.A O no hydrogen 2.983 N/A TYR 114.A N TYR 110.A O no hydrogen 2.817 N/A SER 115.A N THR 111.A O no hydrogen 2.919 N/A SER 115.A OG THR 111.A O no hydrogen 2.627 N/A VAL 116.A N VAL 112.A O no hydrogen 3.010 N/A SER 117.A N GLY 113.A O no hydrogen 2.890 N/A SER 117.A OG GLY 113.A O no hydrogen 2.952 N/A SER 117.A OG SER 333.A O no hydrogen 2.329 N/A LEU 118.A N TYR 114.A O no hydrogen 2.812 N/A ALA 119.A N SER 115.A O no hydrogen 2.971 N/A SER 120.A N VAL 116.A O no hydrogen 2.958 N/A SER 120.A OG VAL 116.A O no hydrogen 2.911 N/A SER 120.A OG SER 117.A O no hydrogen 2.921 N/A LEU 121.A N SER 117.A O no hydrogen 2.841 N/A THR 122.A N LEU 118.A O no hydrogen 2.887 N/A THR 122.A OG1 LEU 118.A O no hydrogen 2.845 N/A VAL 123.A N ALA 119.A O no hydrogen 3.020 N/A ALA 124.A N SER 120.A O no hydrogen 2.869 N/A VAL 125.A N LEU 121.A O no hydrogen 2.848 N/A LEU 126.A N THR 122.A O no hydrogen 2.955 N/A ILE 127.A N VAL 123.A O no hydrogen 2.939 N/A LEU 128.A N ALA 124.A O no hydrogen 2.892 N/A ALA 129.A N VAL 125.A O no hydrogen 2.904 N/A TYR 130.A N LEU 126.A O no hydrogen 2.925 N/A PHE 131.A N ILE 127.A O no hydrogen 3.296 N/A HIS 135.A N ARG 132.A O no hydrogen 2.981 N/A HIS 135.A NE2 ALA 129.A O no hydrogen 3.225 N/A THR 137.A OG1 GLU 207.A OE2 no hydrogen 2.404 N/A ARG 138.A NH2 GLU 349.A OE1 no hydrogen 3.301 N/A ASN 139.A ND2 LEU 134.A O no hydrogen 2.450 N/A TYR 140.A N CYS 136.A O no hydrogen 2.461 N/A ILE 141.A N THR 137.A O no hydrogen 2.926 N/A HIS 142.A N ARG 138.A O no hydrogen 2.888 N/A HIS 142.A ND1 GLU 192.A OE1 no hydrogen 2.534 N/A MET 143.A N ASN 139.A O no hydrogen 2.857 N/A HIS 144.A N TYR 140.A O no hydrogen 2.972 N/A LEU 145.A N ILE 141.A O no hydrogen 2.866 N/A PHE 146.A N HIS 142.A O no hydrogen 2.789 N/A LEU 147.A N MET 143.A O no hydrogen 2.880 N/A SER 148.A N HIS 144.A O no hydrogen 2.900 N/A SER 148.A OG LEU 145.A O no hydrogen 2.611 N/A PHE 149.A N LEU 145.A O no hydrogen 2.903 N/A MET 150.A N PHE 146.A O no hydrogen 2.931 N/A LEU 151.A N LEU 147.A O no hydrogen 2.857 N/A ARG 152.A N SER 148.A O no hydrogen 2.895 N/A ARG 152.A NH1 ASN 185.A OD1 no hydrogen 2.618 N/A ARG 152.A NH1 TYR 305.A OH no hydrogen 2.917 N/A ARG 152.A NH2 TYR 305.A OH no hydrogen 3.513 N/A ALA 153.A N PHE 149.A O no hydrogen 2.950 N/A VAL 154.A N MET 150.A O no hydrogen 2.878 N/A SER 155.A N LEU 151.A O no hydrogen 2.862 N/A ILE 156.A N ARG 152.A O no hydrogen 2.921 N/A PHE 157.A N ALA 153.A O no hydrogen 2.957 N/A VAL 158.A N VAL 154.A O no hydrogen 2.883 N/A LYS 159.A N SER 155.A O no hydrogen 2.862 N/A LYS 159.A NZ ASP 160.A OD1 no hydrogen 2.794 N/A ASP 160.A N ILE 156.A O no hydrogen 2.911 N/A ALA 161.A N PHE 157.A O no hydrogen 2.942 N/A VAL 162.A N VAL 158.A O no hydrogen 2.906 N/A LEU 163.A N LYS 159.A O no hydrogen 2.843 N/A TYR 164.A N ASP 160.A O no hydrogen 2.931 N/A SER 165.A OG ALA 161.A O no hydrogen 2.936 N/A ARG 172.A NE GLY 240.A O no hydrogen 2.861 N/A ARG 172.A NH1 ASN 238.A OD1 no hydrogen 2.478 N/A VAL 173.A N ALA 169.A O no hydrogen 2.902 N/A VAL 175.A N CYS 171.A O no hydrogen 2.968 N/A THR 176.A N ARG 172.A O no hydrogen 2.883 N/A THR 176.A OG1 ARG 172.A O no hydrogen 2.755 N/A PHE 177.A N VAL 173.A O no hydrogen 2.890 N/A PHE 178.A N ALA 174.A O no hydrogen 2.912 N/A LEU 179.A N VAL 175.A O no hydrogen 2.969 N/A TYR 180.A N THR 176.A O no hydrogen 2.874 N/A TYR 180.A OH TRP 219.A O no hydrogen 3.010 N/A PHE 181.A N PHE 177.A O no hydrogen 2.896 N/A LEU 182.A N PHE 178.A O no hydrogen 2.964 N/A ALA 183.A N LEU 179.A O no hydrogen 2.949 N/A THR 184.A N TYR 180.A O no hydrogen 2.867 N/A THR 184.A OG1 TYR 180.A O no hydrogen 3.465 N/A THR 184.A OG1 PHE 181.A O no hydrogen 2.572 N/A ASN 185.A N PHE 181.A O no hydrogen 2.936 N/A ASN 185.A ND2 SER 148.A OG no hydrogen 3.067 N/A TYR 186.A N LEU 182.A O no hydrogen 3.008 N/A TYR 187.A N ALA 183.A O no hydrogen 2.877 N/A TRP 188.A N THR 184.A O no hydrogen 2.846 N/A ILE 189.A N ASN 185.A O no hydrogen 2.973 N/A LEU 190.A N TYR 186.A O no hydrogen 2.972 N/A VAL 191.A N TYR 187.A O no hydrogen 2.814 N/A GLU 192.A N TRP 188.A O no hydrogen 2.893 N/A GLY 193.A N ILE 189.A O no hydrogen 3.035 N/A LEU 194.A N LEU 190.A O no hydrogen 2.847 N/A TYR 195.A N VAL 191.A O no hydrogen 2.832 N/A LEU 196.A N GLU 192.A O no hydrogen 3.008 N/A HIS 197.A N GLY 193.A O no hydrogen 2.916 N/A SER 198.A N LEU 194.A O no hydrogen 2.858 N/A SER 198.A OG LEU 194.A O no hydrogen 3.428 N/A SER 198.A OG TYR 195.A O no hydrogen 2.777 N/A LEU 199.A N TYR 195.A O no hydrogen 2.893 N/A ILE 200.A N LEU 196.A O no hydrogen 2.985 N/A PHE 201.A N HIS 197.A O no hydrogen 2.862 N/A TYR 210.A N GLU 207.A O no hydrogen 3.327 N/A LEU 211.A N GLU 207.A O no hydrogen 2.898 N/A PHE 214.A N TYR 210.A O no hydrogen 2.858 N/A THR 215.A N LEU 211.A O no hydrogen 2.932 N/A THR 215.A OG1 LEU 211.A O no hydrogen 3.103 N/A VAL 216.A N TRP 212.A O no hydrogen 2.934 N/A PHE 217.A N GLY 213.A O no hydrogen 2.869 N/A GLY 218.A N PHE 214.A O no hydrogen 2.877 N/A TRP 219.A N THR 215.A O no hydrogen 2.930 N/A TRP 219.A NE1 HIS 144.A ND1 no hydrogen 3.295 N/A GLY 220.A N VAL 216.A O no hydrogen 2.523 N/A VAL 224.A N GLY 220.A O no hydrogen 3.080 N/A VAL 224.A N LEU 221.A O no hydrogen 2.987 N/A VAL 226.A N PRO 222.A O no hydrogen 2.943 N/A ALA 227.A N ALA 223.A O no hydrogen 2.866 N/A VAL 228.A N VAL 224.A O no hydrogen 2.936 N/A TRP 229.A N PHE 225.A O no hydrogen 2.868 N/A VAL 230.A N VAL 226.A O no hydrogen 2.906 N/A SER 231.A N ALA 227.A O no hydrogen 2.891 N/A SER 231.A OG ALA 227.A O no hydrogen 3.399 N/A SER 231.A OG VAL 228.A O no hydrogen 2.719 N/A VAL 232.A N VAL 228.A O no hydrogen 2.924 N/A ARG 233.A N TRP 229.A O no hydrogen 2.860 N/A ARG 233.A NH1 LEU 244.A O no hydrogen 2.851 N/A ARG 233.A NH2 LEU 244.A O no hydrogen 2.962 N/A ALA 234.A N VAL 230.A O no hydrogen 2.909 N/A THR 235.A N SER 231.A O no hydrogen 2.904 N/A THR 235.A OG1 SER 231.A O no hydrogen 2.875 N/A LEU 236.A N VAL 232.A O no hydrogen 2.891 N/A ALA 237.A N ARG 233.A O no hydrogen 2.960 N/A ASN 238.A N ARG 233.A O no hydrogen 2.521 N/A ASN 238.A ND2 ALA 234.A O no hydrogen 3.111 N/A CYS 241.A SG ALA 166.A O no hydrogen 3.403 N/A LYS 249.A N SER 246.A O no hydrogen 3.293 N/A LYS 249.A NZ VAL 232.A O no hydrogen 2.839 N/A TRP 251.A N ASN 248.A O no hydrogen 2.915 N/A ILE 252.A N LYS 249.A O no hydrogen 3.344 N/A GLN 254.A N LYS 250.A O no hydrogen 3.462 N/A GLN 254.A NE2 TYR 313.A OH no hydrogen 2.591 N/A VAL 255.A N TRP 251.A O no hydrogen 3.217 N/A ILE 257.A N ILE 253.A O no hydrogen 3.453 N/A LEU 258.A N GLN 254.A O no hydrogen 3.011 N/A ALA 259.A N VAL 255.A O no hydrogen 3.085 N/A SER 260.A N PRO 256.A O no hydrogen 2.814 N/A SER 260.A OG ILE 257.A O no hydrogen 2.297 N/A ILE 261.A N ILE 257.A O no hydrogen 2.938 N/A VAL 262.A N LEU 258.A O no hydrogen 2.831 N/A LEU 263.A N ALA 259.A O no hydrogen 2.829 N/A ASN 264.A N SER 260.A O no hydrogen 2.740 N/A ASN 264.A ND2 ILE 189.A O no hydrogen 3.171 N/A PHE 265.A N ILE 261.A O no hydrogen 2.854 N/A ILE 266.A N VAL 262.A O no hydrogen 3.078 N/A LEU 267.A N LEU 263.A O no hydrogen 2.962 N/A PHE 268.A N ASN 264.A O no hydrogen 2.705 N/A ILE 269.A N PHE 265.A O no hydrogen 2.972 N/A ASN 270.A N ILE 266.A O no hydrogen 2.972 N/A ILE 271.A N LEU 267.A O no hydrogen 2.934 N/A VAL 272.A N PHE 268.A O no hydrogen 2.921 N/A ARG 273.A N ILE 269.A O no hydrogen 2.718 N/A VAL 274.A N ASN 270.A O no hydrogen 2.951 N/A LEU 275.A N ILE 271.A O no hydrogen 2.877 N/A ALA 276.A N VAL 272.A O no hydrogen 2.757 N/A THR 277.A N ARG 273.A O no hydrogen 2.709 N/A THR 277.A OG1 ARG 273.A O no hydrogen 3.013 N/A LYS 278.A N VAL 274.A O no hydrogen 2.584 N/A LEU 279.A N LEU 275.A O no hydrogen 2.989 N/A GLU 281.A N THR 277.A O no hydrogen 2.820 N/A GLU 281.A N LYS 278.A O no hydrogen 2.932 N/A THR 282.A N LYS 278.A O no hydrogen 3.266 N/A THR 282.A OG1 LYS 278.A O no hydrogen 3.496 N/A THR 282.A OG1 LEU 279.A O no hydrogen 3.567 N/A ARG 288.A N ARG 284.A O no hydrogen 2.905 N/A LYS 289.A N GLN 285.A O no hydrogen 2.902 N/A LEU 290.A N GLN 286.A O no hydrogen 2.903 N/A LEU 291.A N TYR 287.A O no hydrogen 2.892 N/A LYS 292.A N ARG 288.A O no hydrogen 2.918 N/A SER 293.A N LYS 289.A O no hydrogen 2.896 N/A SER 293.A OG LYS 289.A O no hydrogen 3.395 N/A THR 294.A N LEU 290.A O no hydrogen 2.917 N/A LEU 295.A N LEU 291.A O no hydrogen 2.926 N/A VAL 296.A N LYS 292.A O no hydrogen 2.945 N/A LEU 297.A N SER 293.A O no hydrogen 2.891 N/A LEU 297.A N THR 294.A O no hydrogen 3.260 N/A MET 298.A N THR 294.A O no hydrogen 2.930 N/A PHE 301.A N LEU 297.A O no hydrogen 3.348 N/A PHE 301.A N MET 298.A O no hydrogen 3.266 N/A GLY 302.A N PRO 299.A O no hydrogen 3.458 N/A VAL 303.A N MET 298.A O no hydrogen 3.197 N/A HIS 304.A NE2 ASN 332.A OD1 no hydrogen 2.764 N/A TYR 305.A N GLY 302.A O no hydrogen 3.106 N/A TYR 305.A OH GLN 335.A OE1 no hydrogen 2.942 N/A ILE 306.A N VAL 303.A O no hydrogen 2.933 N/A VAL 307.A N HIS 304.A O no hydrogen 3.440 N/A THR 311.A OG1 PHE 308.A O no hydrogen 2.821 N/A GLY 318.A N VAL 316.A O no hydrogen 2.818 N/A GLN 322.A N GLY 318.A O no hydrogen 2.968 N/A VAL 323.A N THR 319.A O no hydrogen 2.909 N/A GLN 324.A N LEU 320.A O no hydrogen 2.903 N/A MET 325.A N TRP 321.A O no hydrogen 2.870 N/A HIS 326.A N GLN 322.A O no hydrogen 2.923 N/A HIS 326.A ND1 GLN 322.A O no hydrogen 2.459 N/A TYR 327.A N VAL 323.A O no hydrogen 2.941 N/A GLU 328.A N GLN 324.A O no hydrogen 2.864 N/A MET 329.A N MET 325.A O no hydrogen 2.853 N/A LEU 330.A N HIS 326.A O no hydrogen 2.991 N/A PHE 331.A N TYR 327.A O no hydrogen 2.933 N/A ASN 332.A N GLU 328.A O no hydrogen 2.808 N/A ASN 332.A ND2 GLU 328.A OE1 no hydrogen 2.943 N/A SER 333.A N MET 329.A O no hydrogen 2.934 N/A SER 333.A OG MET 329.A O no hydrogen 2.677 N/A SER 333.A OG LEU 330.A O no hydrogen 2.756 N/A PHE 334.A N LEU 330.A O no hydrogen 2.984 N/A GLN 335.A N ASN 332.A O no hydrogen 3.412 N/A GLN 335.A NE2 PRO 299.A O no hydrogen 2.827 N/A PHE 337.A N SER 117.A OG no hydrogen 2.989 N/A PHE 338.A N PHE 334.A O no hydrogen 2.908 N/A VAL 339.A N GLN 335.A O no hydrogen 2.891 N/A ALA 340.A N GLY 336.A O no hydrogen 2.902 N/A ILE 341.A N PHE 337.A O no hydrogen 2.914 N/A ILE 342.A N PHE 338.A O no hydrogen 2.919 N/A TYR 343.A N VAL 339.A O no hydrogen 2.909 N/A CYS 344.A N ALA 340.A O no hydrogen 2.908 N/A CYS 344.A SG ALA 124.A O no hydrogen 3.798 N/A PHE 345.A N ALA 340.A O no hydrogen 3.134 N/A CYS 346.A N ILE 341.A O no hydrogen 2.639 N/A VAL 350.A N ASN 347.A OD1 no hydrogen 3.353 N/A GLN 351.A N ASN 347.A O no hydrogen 2.800 N/A GLN 351.A NE2 PHE 345.A O no hydrogen 2.811 N/A ALA 352.A N GLY 348.A O no hydrogen 2.901 N/A GLU 353.A N GLU 349.A O no hydrogen 2.920 N/A ILE 354.A N VAL 350.A O no hydrogen 2.892 N/A LYS 355.A N GLN 351.A O no hydrogen 2.911 N/A LYS 356.A N ALA 352.A O no hydrogen 2.900 N/A SER 357.A N GLU 353.A O no hydrogen 2.909 N/A TRP 358.A N ILE 354.A O no hydrogen 2.904 N/A SER 359.A N LYS 355.A O no hydrogen 2.891 N/A ARG 360.A N LYS 356.A O no hydrogen 2.926 N/A TRP 361.A N SER 357.A O no hydrogen 2.885 N/A THR 362.A N TRP 358.A O no hydrogen 2.910 N/A THR 362.A OG1 TRP 358.A O no hydrogen 3.102 N/A THR 362.A OG1 SER 359.A O no hydrogen 2.766 N/A LEU 363.A N SER 359.A O no hydrogen 2.986 N/A