Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8flr_R.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A OG1 GLU 5.A OE1 no hydrogen 2.899 N/A GLU 5.A N GLU 5.A OE1 no hydrogen 2.791 N/A GLU 6.A N THR 3.A OG1 no hydrogen 3.367 N/A GLN 7.A N THR 3.A O no hydrogen 3.121 N/A GLN 7.A NE2 GLN 7.A O no hydrogen 3.231 N/A GLN 7.A NE2 TYR 54.A O no hydrogen 2.968 N/A ILE 8.A N LYS 4.A O no hydrogen 2.892 N/A PHE 9.A N GLU 5.A O no hydrogen 2.898 N/A LEU 10.A N GLU 6.A O no hydrogen 2.917 N/A LEU 11.A N GLN 7.A O no hydrogen 2.873 N/A HIS 12.A N ILE 8.A O no hydrogen 2.888 N/A ARG 13.A N PHE 9.A O no hydrogen 2.933 N/A ALA 14.A N LEU 10.A O no hydrogen 2.901 N/A GLN 15.A N LEU 11.A O no hydrogen 2.857 N/A ALA 16.A N HIS 12.A O no hydrogen 2.911 N/A GLN 17.A N ARG 13.A O no hydrogen 2.930 N/A CYS 18.A N ALA 14.A O no hydrogen 2.878 N/A GLU 19.A N GLN 15.A O no hydrogen 2.882 N/A LYS 20.A N ALA 16.A O no hydrogen 2.927 N/A ARG 21.A N GLN 17.A O no hydrogen 2.910 N/A LEU 22.A N CYS 18.A O no hydrogen 2.869 N/A LYS 23.A N GLU 19.A O no hydrogen 2.919 N/A GLU 24.A N LYS 20.A O no hydrogen 2.969 N/A ARG 26.A N ARG 70.A O no hydrogen 3.097 N/A CYS 28.A N GLY 41.A O no hydrogen 2.984 N/A CYS 28.A SG ASP 69.A O no hydrogen 3.960 N/A TRP 32.A NE1 GLN 15.A OE1 no hydrogen 2.603 N/A TRP 38.A N GLU 31.A O no hydrogen 3.491 N/A GLY 41.A N CYS 28.A O no hydrogen 3.274 N/A GLU 45.A N ALA 42.A O no hydrogen 3.168 N/A VAL 47.A N ARG 66.A O no hydrogen 2.888 N/A VAL 49.A N ALA 64.A O no hydrogen 2.907 N/A CYS 51.A N GLY 62.A O no hydrogen 3.239 N/A CYS 51.A SG ASN 59.A O no hydrogen 3.661 N/A TYR 56.A N GLN 7.A OE1 no hydrogen 3.423 N/A ASN 59.A N CYS 90.A O no hydrogen 3.381 N/A GLY 62.A N ASN 59.A O no hydrogen 2.587 N/A ALA 64.A N VAL 49.A O no hydrogen 2.875 N/A TYR 65.A N ASN 86.A O no hydrogen 3.060 N/A ARG 66.A N VAL 47.A O no hydrogen 2.912 N/A ARG 66.A NE TRP 84.A O no hydrogen 3.267 N/A CYS 68.A SG GLY 41.A O no hydrogen 3.537 N/A CYS 68.A SG ALA 42.A O no hydrogen 3.230 N/A CYS 68.A SG ASP 69.A O no hydrogen 3.224 N/A ASP 69.A N SER 73.A O no hydrogen 3.251 N/A TRP 74.A NE1 LEU 29.A O no hydrogen 2.367 N/A GLU 75.A N ARG 67.A O no hydrogen 2.968 N/A VAL 77.A N ARG 82.A O no hydrogen 2.885 N/A HIS 80.A N VAL 77.A O no hydrogen 3.337 N/A TRP 84.A N GLU 75.A O no hydrogen 2.791 N/A LYS 92.A N GLU 89.A O no hydrogen 3.166 N/A LEU 94.A N VAL 91.A O no hydrogen 2.929 N/A THR 95.A OG1 LEU 94.A O no hydrogen 2.700 N/A GLU 102.A N THR 98.A O no hydrogen 2.923 N/A VAL 103.A N ARG 99.A O no hydrogen 2.893 N/A PHE 104.A N GLU 100.A O no hydrogen 2.928 N/A ASP 105.A N ARG 101.A O no hydrogen 2.911 N/A ARG 106.A N GLU 102.A O no hydrogen 2.907 N/A ARG 106.A NH1 HIS 326.A NE2 no hydrogen 3.388 N/A LEU 107.A N VAL 103.A O no hydrogen 2.910 N/A GLY 108.A N PHE 104.A O no hydrogen 3.007 N/A MET 109.A N ASP 105.A O no hydrogen 2.896 N/A ILE 110.A N ARG 106.A O no hydrogen 2.936 N/A TYR 111.A N LEU 107.A O no hydrogen 2.962 N/A TYR 111.A OH ASP 161.A OD2 no hydrogen 3.297 N/A THR 112.A N GLY 108.A O no hydrogen 2.884 N/A THR 112.A OG1 GLY 108.A O no hydrogen 2.568 N/A VAL 113.A N MET 109.A O no hydrogen 2.967 N/A GLY 114.A N ILE 110.A O no hydrogen 2.960 N/A TYR 115.A N TYR 111.A O no hydrogen 2.837 N/A SER 116.A N THR 112.A O no hydrogen 2.908 N/A SER 116.A OG THR 112.A O no hydrogen 2.623 N/A VAL 117.A N VAL 113.A O no hydrogen 3.005 N/A SER 118.A N GLY 114.A O no hydrogen 2.889 N/A SER 118.A OG GLY 114.A O no hydrogen 3.045 N/A SER 118.A OG SER 333.A O no hydrogen 2.279 N/A LEU 119.A N TYR 115.A O no hydrogen 2.818 N/A ALA 120.A N SER 116.A O no hydrogen 2.979 N/A SER 121.A N VAL 117.A O no hydrogen 2.959 N/A SER 121.A OG VAL 117.A O no hydrogen 2.911 N/A SER 121.A OG SER 118.A O no hydrogen 2.932 N/A LEU 122.A N SER 118.A O no hydrogen 2.842 N/A THR 123.A N LEU 119.A O no hydrogen 2.889 N/A THR 123.A OG1 LEU 119.A O no hydrogen 2.432 N/A VAL 124.A N ALA 120.A O no hydrogen 3.023 N/A ALA 125.A N SER 121.A O no hydrogen 2.881 N/A VAL 126.A N LEU 122.A O no hydrogen 2.854 N/A LEU 127.A N THR 123.A O no hydrogen 2.966 N/A ILE 128.A N VAL 124.A O no hydrogen 2.939 N/A LEU 129.A N ALA 125.A O no hydrogen 2.904 N/A ALA 130.A N VAL 126.A O no hydrogen 2.892 N/A TYR 131.A N LEU 127.A O no hydrogen 2.920 N/A PHE 132.A N ILE 128.A O no hydrogen 3.338 N/A HIS 136.A N ARG 133.A O no hydrogen 2.982 N/A HIS 136.A NE2 ALA 130.A O no hydrogen 3.347 N/A ARG 139.A NH2 GLU 349.A OE2 no hydrogen 3.335 N/A ASN 140.A ND2 LEU 135.A O no hydrogen 2.819 N/A TYR 141.A N CYS 137.A O no hydrogen 2.670 N/A ILE 142.A N THR 138.A O no hydrogen 2.989 N/A HIS 143.A N ARG 139.A O no hydrogen 2.823 N/A HIS 143.A ND1 GLU 192.A OE2 no hydrogen 3.252 N/A MET 144.A N ASN 140.A O no hydrogen 2.825 N/A HIS 145.A N TYR 141.A O no hydrogen 3.389 N/A LEU 146.A N ILE 142.A O no hydrogen 3.028 N/A PHE 147.A N HIS 143.A O no hydrogen 2.873 N/A LEU 148.A N MET 144.A O no hydrogen 2.873 N/A SER 149.A N HIS 145.A O no hydrogen 2.915 N/A SER 149.A OG LEU 146.A O no hydrogen 2.612 N/A PHE 150.A N LEU 146.A O no hydrogen 2.916 N/A MET 151.A N PHE 147.A O no hydrogen 2.940 N/A LEU 152.A N LEU 148.A O no hydrogen 2.878 N/A ARG 153.A N SER 149.A O no hydrogen 2.916 N/A ARG 153.A NH1 ASN 185.A OD1 no hydrogen 2.924 N/A ARG 153.A NH1 TYR 305.A OH no hydrogen 3.140 N/A ARG 153.A NH2 TYR 186.A OH no hydrogen 3.324 N/A ALA 154.A N PHE 150.A O no hydrogen 2.966 N/A VAL 155.A N MET 151.A O no hydrogen 2.899 N/A SER 156.A N LEU 152.A O no hydrogen 2.870 N/A SER 156.A OG LEU 152.A O no hydrogen 3.155 N/A SER 156.A OG ARG 153.A O no hydrogen 2.592 N/A ILE 157.A N ARG 153.A O no hydrogen 2.962 N/A PHE 158.A N ALA 154.A O no hydrogen 2.968 N/A VAL 159.A N VAL 155.A O no hydrogen 2.875 N/A LYS 160.A N SER 156.A O no hydrogen 2.892 N/A LYS 160.A NZ ASP 161.A OD1 no hydrogen 2.381 N/A ASP 161.A N ILE 157.A O no hydrogen 2.922 N/A ALA 162.A N PHE 158.A O no hydrogen 2.935 N/A VAL 163.A N VAL 159.A O no hydrogen 2.869 N/A LEU 164.A N LYS 160.A O no hydrogen 2.910 N/A TYR 165.A N ASP 161.A O no hydrogen 3.098 N/A TYR 165.A OH ASP 243.A OD2 no hydrogen 3.030 N/A SER 166.A OG ALA 162.A O no hydrogen 2.218 N/A CYS 171.A N TYR 168.A O no hydrogen 3.252 N/A ARG 172.A N TYR 168.A O no hydrogen 3.307 N/A ARG 172.A NE GLY 240.A O no hydrogen 2.842 N/A ARG 172.A NH2 GLY 240.A O no hydrogen 3.370 N/A VAL 173.A N ALA 169.A O no hydrogen 2.918 N/A VAL 175.A N CYS 171.A O no hydrogen 2.962 N/A THR 176.A N ARG 172.A O no hydrogen 2.897 N/A THR 176.A OG1 ARG 172.A O no hydrogen 2.798 N/A PHE 177.A N VAL 173.A O no hydrogen 2.902 N/A PHE 178.A N ALA 174.A O no hydrogen 2.918 N/A LEU 179.A N VAL 175.A O no hydrogen 2.962 N/A TYR 180.A N THR 176.A O no hydrogen 2.897 N/A TYR 180.A OH TRP 219.A O no hydrogen 3.035 N/A PHE 181.A N PHE 177.A O no hydrogen 2.905 N/A LEU 182.A N PHE 178.A O no hydrogen 2.962 N/A ALA 183.A N LEU 179.A O no hydrogen 2.946 N/A THR 184.A N TYR 180.A O no hydrogen 2.884 N/A THR 184.A OG1 TYR 180.A O no hydrogen 3.462 N/A THR 184.A OG1 PHE 181.A O no hydrogen 2.573 N/A ASN 185.A N PHE 181.A O no hydrogen 2.938 N/A ASN 185.A ND2 SER 149.A OG no hydrogen 2.896 N/A TYR 186.A N LEU 182.A O no hydrogen 3.000 N/A TYR 187.A N ALA 183.A O no hydrogen 2.893 N/A TRP 188.A N THR 184.A O no hydrogen 2.868 N/A ILE 189.A N ASN 185.A O no hydrogen 2.949 N/A LEU 190.A N TYR 186.A O no hydrogen 2.962 N/A VAL 191.A N TYR 187.A O no hydrogen 2.861 N/A GLU 192.A N TRP 188.A O no hydrogen 2.934 N/A GLY 193.A N ILE 189.A O no hydrogen 3.510 N/A LEU 194.A N LEU 190.A O no hydrogen 2.909 N/A TYR 195.A N VAL 191.A O no hydrogen 2.842 N/A LEU 196.A N GLU 192.A O no hydrogen 2.994 N/A HIS 197.A N GLY 193.A O no hydrogen 2.877 N/A SER 198.A N LEU 194.A O no hydrogen 2.879 N/A SER 198.A OG LEU 194.A O no hydrogen 3.430 N/A SER 198.A OG TYR 195.A O no hydrogen 2.678 N/A LEU 199.A N TYR 195.A O no hydrogen 2.948 N/A ILE 200.A N LEU 196.A O no hydrogen 2.974 N/A PHE 201.A N HIS 197.A O no hydrogen 2.888 N/A MET 202.A N SER 198.A O no hydrogen 2.723 N/A TYR 210.A N SER 206.A O no hydrogen 3.234 N/A LEU 211.A N GLU 207.A O no hydrogen 2.965 N/A GLY 213.A N LYS 209.A O no hydrogen 2.906 N/A PHE 214.A N TYR 210.A O no hydrogen 2.873 N/A THR 215.A N LEU 211.A O no hydrogen 3.095 N/A THR 215.A OG1 LEU 211.A O no hydrogen 2.979 N/A VAL 216.A N TRP 212.A O no hydrogen 2.913 N/A PHE 217.A N GLY 213.A O no hydrogen 2.886 N/A GLY 218.A N PHE 214.A O no hydrogen 2.899 N/A TRP 219.A N THR 215.A O no hydrogen 2.966 N/A GLY 220.A N PHE 217.A O no hydrogen 3.216 N/A LEU 221.A N PHE 217.A O no hydrogen 2.959 N/A VAL 224.A N GLY 220.A O no hydrogen 2.671 N/A PHE 225.A N LEU 221.A O no hydrogen 3.003 N/A VAL 226.A N PRO 222.A O no hydrogen 2.893 N/A ALA 227.A N ALA 223.A O no hydrogen 2.879 N/A VAL 228.A N VAL 224.A O no hydrogen 2.959 N/A TRP 229.A N PHE 225.A O no hydrogen 2.887 N/A VAL 230.A N VAL 226.A O no hydrogen 2.878 N/A SER 231.A N ALA 227.A O no hydrogen 2.911 N/A SER 231.A OG ALA 227.A O no hydrogen 3.533 N/A SER 231.A OG VAL 228.A O no hydrogen 2.751 N/A VAL 232.A N VAL 228.A O no hydrogen 2.944 N/A ARG 233.A N TRP 229.A O no hydrogen 2.834 N/A ARG 233.A NH1 LEU 244.A O no hydrogen 2.919 N/A ARG 233.A NH2 LEU 244.A O no hydrogen 3.210 N/A ALA 234.A N VAL 230.A O no hydrogen 2.907 N/A THR 235.A N SER 231.A O no hydrogen 2.909 N/A THR 235.A OG1 SER 231.A O no hydrogen 2.540 N/A LEU 236.A N VAL 232.A O no hydrogen 2.899 N/A ALA 237.A N ARG 233.A O no hydrogen 2.877 N/A ASN 238.A N ARG 233.A O no hydrogen 2.614 N/A ASN 238.A ND2 ALA 234.A O no hydrogen 3.437 N/A LYS 250.A NZ GLY 247.A O no hydrogen 2.485 N/A TRP 251.A N ASN 248.A O no hydrogen 2.926 N/A ILE 252.A N LYS 249.A O no hydrogen 2.939 N/A ILE 253.A N LYS 250.A O no hydrogen 2.939 N/A GLN 254.A N LYS 250.A O no hydrogen 3.019 N/A GLN 254.A NE2 TYR 313.A OH no hydrogen 2.631 N/A VAL 255.A N TRP 251.A O no hydrogen 2.672 N/A ILE 257.A N ILE 253.A O no hydrogen 3.458 N/A LEU 258.A N GLN 254.A O no hydrogen 2.956 N/A ALA 259.A N VAL 255.A O no hydrogen 3.111 N/A SER 260.A N PRO 256.A O no hydrogen 3.063 N/A SER 260.A OG ILE 257.A O no hydrogen 2.538 N/A ILE 261.A N ILE 257.A O no hydrogen 3.122 N/A VAL 262.A N LEU 258.A O no hydrogen 2.954 N/A LEU 263.A N ALA 259.A O no hydrogen 2.880 N/A ASN 264.A N SER 260.A O no hydrogen 2.720 N/A ASN 264.A ND2 ILE 189.A O no hydrogen 3.055 N/A ASN 264.A ND2 PHE 301.A O no hydrogen 2.632 N/A PHE 265.A N ILE 261.A O no hydrogen 2.906 N/A ILE 266.A N VAL 262.A O no hydrogen 3.068 N/A LEU 267.A N LEU 263.A O no hydrogen 2.991 N/A PHE 268.A N ASN 264.A O no hydrogen 2.759 N/A ILE 269.A N PHE 265.A O no hydrogen 3.040 N/A ASN 270.A N ILE 266.A O no hydrogen 2.926 N/A ILE 271.A N LEU 267.A O no hydrogen 2.722 N/A VAL 272.A N PHE 268.A O no hydrogen 2.764 N/A ARG 273.A N ILE 269.A O no hydrogen 2.667 N/A ARG 273.A NE ASN 270.A OD1 no hydrogen 3.096 N/A ARG 273.A NH2 ASN 270.A OD1 no hydrogen 3.105 N/A VAL 274.A N ASN 270.A O no hydrogen 2.958 N/A LEU 275.A N ILE 271.A O no hydrogen 2.913 N/A ALA 276.A N VAL 272.A O no hydrogen 3.021 N/A THR 277.A N ARG 273.A O no hydrogen 3.066 N/A THR 277.A OG1 ARG 273.A O no hydrogen 3.530 N/A LYS 278.A N VAL 274.A O no hydrogen 2.796 N/A LEU 279.A N LEU 275.A O no hydrogen 2.849 N/A LEU 279.A N ALA 276.A O no hydrogen 2.949 N/A ARG 280.A N ALA 276.A O no hydrogen 2.661 N/A GLU 281.A N THR 277.A O no hydrogen 2.990 N/A THR 282.A OG1 LYS 278.A O no hydrogen 3.309 N/A THR 282.A OG1 LEU 279.A O no hydrogen 3.148 N/A ARG 288.A N ARG 284.A O no hydrogen 2.920 N/A LYS 289.A N GLN 285.A O no hydrogen 2.901 N/A LEU 290.A N GLN 286.A O no hydrogen 2.949 N/A LEU 291.A N TYR 287.A O no hydrogen 2.875 N/A LYS 292.A N ARG 288.A O no hydrogen 2.935 N/A SER 293.A N LYS 289.A O no hydrogen 2.899 N/A SER 293.A OG LYS 289.A O no hydrogen 2.985 N/A THR 294.A N LEU 290.A O no hydrogen 2.951 N/A LEU 295.A N LEU 291.A O no hydrogen 2.914 N/A VAL 296.A N LYS 292.A O no hydrogen 2.958 N/A LEU 297.A N SER 293.A O no hydrogen 2.899 N/A LEU 297.A N THR 294.A O no hydrogen 3.213 N/A MET 298.A N THR 294.A O no hydrogen 2.979 N/A PHE 301.A N LEU 297.A O no hydrogen 3.376 N/A GLY 302.A N PRO 299.A O no hydrogen 3.404 N/A VAL 303.A N MET 298.A O no hydrogen 3.274 N/A HIS 304.A NE2 ASN 332.A OD1 no hydrogen 2.491 N/A TYR 305.A N GLY 302.A O no hydrogen 3.259 N/A TYR 305.A OH GLN 335.A OE1 no hydrogen 2.894 N/A ILE 306.A N VAL 303.A O no hydrogen 2.928 N/A THR 311.A N PHE 308.A O no hydrogen 3.365 N/A THR 311.A OG1 PHE 308.A O no hydrogen 3.346 N/A THR 314.A OG1 PRO 312.A O no hydrogen 3.449 N/A GLY 318.A N VAL 316.A O no hydrogen 2.857 N/A GLN 322.A N GLY 318.A O no hydrogen 3.183 N/A VAL 323.A N THR 319.A O no hydrogen 2.924 N/A GLN 324.A N LEU 320.A O no hydrogen 2.902 N/A MET 325.A N TRP 321.A O no hydrogen 2.841 N/A HIS 326.A N GLN 322.A O no hydrogen 2.918 N/A HIS 326.A ND1 GLN 322.A O no hydrogen 2.353 N/A TYR 327.A N VAL 323.A O no hydrogen 2.960 N/A TYR 327.A OH HIS 304.A O no hydrogen 3.134 N/A GLU 328.A N GLN 324.A O no hydrogen 2.859 N/A MET 329.A N MET 325.A O no hydrogen 2.868 N/A LEU 330.A N HIS 326.A O no hydrogen 3.014 N/A PHE 331.A N TYR 327.A O no hydrogen 2.910 N/A ASN 332.A N GLU 328.A O no hydrogen 2.817 N/A ASN 332.A ND2 GLU 328.A OE1 no hydrogen 3.462 N/A SER 333.A N MET 329.A O no hydrogen 2.913 N/A SER 333.A OG MET 329.A O no hydrogen 2.739 N/A SER 333.A OG LEU 330.A O no hydrogen 2.872 N/A PHE 334.A N LEU 330.A O no hydrogen 3.000 N/A GLN 335.A N ASN 332.A O no hydrogen 3.426 N/A GLN 335.A NE2 PRO 299.A O no hydrogen 2.800 N/A PHE 337.A N SER 118.A OG no hydrogen 3.030 N/A PHE 338.A N PHE 334.A O no hydrogen 2.895 N/A VAL 339.A N GLN 335.A O no hydrogen 2.889 N/A ALA 340.A N GLY 336.A O no hydrogen 2.898 N/A ILE 341.A N PHE 337.A O no hydrogen 2.933 N/A ILE 342.A N PHE 338.A O no hydrogen 2.912 N/A TYR 343.A N VAL 339.A O no hydrogen 2.894 N/A TYR 343.A OH VAL 296.A O no hydrogen 2.776 N/A CYS 344.A N ALA 340.A O no hydrogen 2.918 N/A CYS 344.A SG ALA 125.A O no hydrogen 3.568 N/A PHE 345.A N ALA 340.A O no hydrogen 3.329 N/A CYS 346.A N ILE 341.A O no hydrogen 2.585 N/A CYS 346.A SG ILE 341.A O no hydrogen 3.263 N/A GLU 349.A N ASN 347.A OD1 no hydrogen 3.365 N/A GLN 351.A N ASN 347.A O no hydrogen 2.969 N/A GLN 351.A NE2 PHE 345.A O no hydrogen 2.616 N/A ALA 352.A N GLY 348.A O no hydrogen 2.886 N/A GLU 353.A N GLU 349.A O no hydrogen 2.925 N/A ILE 354.A N VAL 350.A O no hydrogen 2.878 N/A LYS 355.A N GLN 351.A O no hydrogen 2.905 N/A LYS 356.A N ALA 352.A O no hydrogen 2.898 N/A SER 357.A N GLU 353.A O no hydrogen 2.896 N/A TRP 358.A N ILE 354.A O no hydrogen 2.907 N/A SER 359.A N LYS 355.A O no hydrogen 2.910 N/A ARG 360.A N LYS 356.A O no hydrogen 2.916 N/A TRP 361.A N SER 357.A O no hydrogen 2.880 N/A THR 362.A N TRP 358.A O no hydrogen 2.921 N/A THR 362.A OG1 TRP 358.A O no hydrogen 2.929 N/A THR 362.A OG1 SER 359.A O no hydrogen 2.744 N/A LEU 363.A N SER 359.A O no hydrogen 3.093 N/A