Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8g66_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 4.A N TYR 8.A O no hydrogen 2.600 N/A LYS 7.A N VAL 4.A O no hydrogen 3.242 N/A TYR 8.A N VAL 4.A O no hydrogen 2.876 N/A LYS 9.A N ILE 22.A O no hydrogen 2.989 N/A LEU 10.A N PHE 2.A O no hydrogen 3.089 N/A VAL 11.A N LEU 20.A O no hydrogen 2.735 N/A ARG 12.A N LEU 20.A O no hydrogen 3.507 N/A ILE 14.A N ILE 18.A O no hydrogen 2.856 N/A GLY 15.A N ILE 18.A O no hydrogen 2.737 N/A SER 16.A OG ASP 17.A OD1 no hydrogen 3.200 N/A ILE 18.A N GLY 15.A O no hydrogen 2.918 N/A TYR 19.A N VAL 32.A O no hydrogen 2.918 N/A ALA 21.A N VAL 30.A O no hydrogen 2.791 N/A ILE 22.A N LYS 9.A O no hydrogen 2.871 N/A ASN 23.A N GLU 28.A O no hydrogen 2.779 N/A ASN 23.A ND2 GLU 28.A OE1 no hydrogen 3.354 N/A ILE 24.A N LYS 7.A O no hydrogen 2.628 N/A THR 25.A N ASN 23.A OD1 no hydrogen 2.865 N/A THR 25.A OG1 ASN 23.A OD1 no hydrogen 2.807 N/A GLY 27.A N ASN 23.A O no hydrogen 2.648 N/A GLU 28.A N ASN 26.A OD1 no hydrogen 2.793 N/A VAL 30.A N ALA 21.A O no hydrogen 2.916 N/A ALA 31.A N MET 77.A O no hydrogen 2.991 N/A VAL 32.A N TYR 19.A O no hydrogen 2.923 N/A LYS 33.A N LEU 75.A O no hydrogen 2.783 N/A LYS 33.A NZ GLU 47.A OE1 no hydrogen 2.668 N/A LEU 34.A N ASP 17.A O no hydrogen 3.103 N/A GLU 35.A N ASN 73.A O no hydrogen 2.880 N/A SER 36.A OG GLN 37.A O no hydrogen 2.907 N/A GLN 37.A N ASP 71.A O no hydrogen 2.915 N/A GLN 43.A N GLU 35.A OE1 no hydrogen 2.579 N/A GLN 43.A NE2 GLU 47.A OE1 no hydrogen 2.711 N/A GLN 43.A NE2 ASP 144.A OD1 no hydrogen 3.122 N/A LEU 44.A N GLU 35.A OE1 no hydrogen 2.781 N/A TYR 46.A OH ALA 148.A O no hydrogen 2.244 N/A GLU 47.A N GLN 43.A O no hydrogen 2.795 N/A SER 48.A N LEU 44.A O no hydrogen 2.796 N/A SER 48.A OG LEU 45.A O no hydrogen 2.825 N/A LYS 49.A N LEU 45.A O no hydrogen 3.085 N/A LEU 50.A N TYR 46.A O no hydrogen 2.932 N/A TYR 51.A N GLU 47.A O no hydrogen 2.893 N/A LYS 52.A N LYS 49.A O no hydrogen 3.305 N/A LEU 54.A N LEU 50.A O no hydrogen 2.813 N/A GLN 55.A NE2 PRO 61.A O no hydrogen 3.225 N/A HIS 62.A N ASP 78.A OD2 no hydrogen 2.513 N/A ARG 64.A N VAL 76.A O no hydrogen 2.801 N/A ARG 64.A NE GLU 28.A OE2 no hydrogen 2.637 N/A ARG 64.A NH1 ASP 78.A OD1 no hydrogen 2.536 N/A ARG 64.A NH2 GLU 28.A OE2 no hydrogen 2.661 N/A ARG 64.A NH2 ASP 78.A OD1 no hydrogen 3.169 N/A TRP 65.A N VAL 76.A O no hydrogen 3.103 N/A GLY 67.A N VAL 74.A O no hydrogen 3.247 N/A GLN 68.A NE2 ASN 73.A OD1 no hydrogen 3.159 N/A GLU 69.A N TYR 72.A O no hydrogen 3.338 N/A TYR 72.A N GLU 69.A O no hydrogen 3.204 N/A ASN 73.A N GLU 35.A O no hydrogen 2.490 N/A VAL 74.A N GLY 67.A O no hydrogen 2.769 N/A LEU 75.A N LYS 33.A O no hydrogen 2.961 N/A VAL 76.A N TRP 65.A O no hydrogen 2.715 N/A MET 77.A N ALA 31.A O no hydrogen 2.886 N/A ASP 78.A N HIS 62.A O no hydrogen 3.007 N/A GLY 81.A N MET 131.A O no hydrogen 2.579 N/A SER 83.A N ASP 86.A OD2 no hydrogen 3.044 N/A SER 83.A OG PRO 126.A O no hydrogen 3.400 N/A LEU 84.A N PHE 129.A O no hydrogen 2.845 N/A ASP 86.A N SER 83.A OG no hydrogen 3.169 N/A LEU 87.A N SER 83.A O no hydrogen 3.000 N/A PHE 88.A N LEU 84.A O no hydrogen 2.774 N/A ASN 89.A N GLU 85.A O no hydrogen 3.155 N/A PHE 90.A N ASP 86.A O no hydrogen 2.964 N/A CYS 91.A N LEU 87.A O no hydrogen 3.079 N/A CYS 91.A SG LEU 87.A O no hydrogen 3.387 N/A SER 92.A N ASN 89.A O no hydrogen 3.228 N/A ARG 93.A N PHE 88.A O no hydrogen 2.742 N/A ARG 93.A NH1 TYR 199.A OH no hydrogen 2.934 N/A ARG 93.A NH2 GLU 85.A OE2 no hydrogen 2.714 N/A ARG 93.A NH2 ASN 89.A OD1 no hydrogen 2.770 N/A THR 96.A N ASP 283.A OD2 no hydrogen 2.533 N/A THR 96.A OG1 ASP 283.A OD1 no hydrogen 2.863 N/A THR 96.A OG1 ASP 283.A OD2 no hydrogen 3.401 N/A LYS 98.A NZ ASP 279.A OD1 no hydrogen 2.997 N/A LYS 98.A NZ ASP 279.A OD2 no hydrogen 3.271 N/A THR 99.A N THR 96.A OG1 no hydrogen 3.367 N/A VAL 100.A N THR 96.A O no hydrogen 3.213 N/A LEU 101.A N MET 97.A O no hydrogen 3.091 N/A MET 102.A N LYS 98.A O no hydrogen 2.884 N/A LEU 103.A N THR 99.A O no hydrogen 3.016 N/A ALA 104.A N VAL 100.A O no hydrogen 2.483 N/A ASP 105.A N LEU 101.A O no hydrogen 3.232 N/A ASP 105.A N MET 102.A O no hydrogen 3.199 N/A GLN 106.A NE2 ASN 138.A O no hydrogen 2.874 N/A MET 107.A N LEU 103.A O no hydrogen 3.002 N/A ILE 108.A N ALA 104.A O no hydrogen 2.880 N/A SER 109.A N ASP 105.A O no hydrogen 3.169 N/A SER 109.A OG ASP 105.A O no hydrogen 3.399 N/A ARG 110.A N GLN 106.A O no hydrogen 2.876 N/A ARG 110.A NH1 GLN 106.A OE1 no hydrogen 3.107 N/A ARG 110.A NH1 LEU 140.A O no hydrogen 2.777 N/A ILE 111.A N MET 107.A O no hydrogen 3.316 N/A GLU 112.A N ILE 108.A O no hydrogen 2.953 N/A TYR 113.A N SER 109.A O no hydrogen 2.874 N/A TYR 113.A OH LEU 54.A O no hydrogen 3.268 N/A VAL 114.A N ARG 110.A O no hydrogen 3.292 N/A HIS 115.A N ILE 111.A O no hydrogen 3.019 N/A HIS 115.A ND1 TYR 260.A OH no hydrogen 2.749 N/A HIS 115.A NE2 ASP 189.A OD2 no hydrogen 2.864 N/A THR 116.A N GLU 112.A O no hydrogen 2.931 N/A THR 116.A N TYR 113.A O no hydrogen 2.828 N/A THR 116.A OG1 TYR 113.A O no hydrogen 2.330 N/A LYS 117.A N TYR 113.A O no hydrogen 3.273 N/A ASN 118.A N HIS 115.A O no hydrogen 3.309 N/A ASN 118.A ND2 ASN 154.A OD1 no hydrogen 2.755 N/A PHE 119.A N VAL 114.A O no hydrogen 3.284 N/A ILE 120.A N LYS 149.A O no hydrogen 2.848 N/A HIS 121.A N ASP 189.A OD2 no hydrogen 2.832 N/A HIS 121.A NE2 ILE 143.A O no hydrogen 2.964 N/A ARG 122.A N ASP 189.A OD1 no hydrogen 3.109 N/A ARG 122.A NE LEU 147.A O no hydrogen 3.109 N/A ASP 123.A N HIS 121.A ND1 no hydrogen 2.997 N/A LYS 125.A NZ ASP 123.A OD2 no hydrogen 3.286 N/A ASN 128.A N LYS 125.A O no hydrogen 2.933 N/A ASN 128.A ND2 ASP 123.A O no hydrogen 2.940 N/A ASN 128.A ND2 ASP 123.A OD2 no hydrogen 3.285 N/A PHE 129.A N PRO 126.A O no hydrogen 3.389 N/A LEU 130.A N PHE 141.A O no hydrogen 2.839 N/A MET 131.A N PRO 82.A O no hydrogen 3.199 N/A GLY 132.A N LYS 139.A O no hydrogen 3.131 N/A HIS 136.A N ILE 133.A O no hydrogen 3.041 N/A CYS 137.A N GLY 134.A O no hydrogen 3.314 N/A CYS 137.A SG ASN 138.A OD1 no hydrogen 3.701 N/A ASN 138.A ND2 TYR 280.A O no hydrogen 3.390 N/A LYS 139.A N HIS 136.A O no hydrogen 3.104 N/A LEU 140.A N GLN 106.A OE1 no hydrogen 2.740 N/A PHE 141.A N LEU 130.A O no hydrogen 2.494 N/A LEU 142.A N GLY 59.A O no hydrogen 3.265 N/A ILE 143.A N ASN 128.A O no hydrogen 3.041 N/A PHE 145.A N GLU 47.A OE2 no hydrogen 3.212 N/A ALA 148.A N PHE 145.A O no hydrogen 3.274 N/A LYS 149.A N ILE 120.A O no hydrogen 3.018 N/A LYS 149.A NZ GLU 183.A OE2 no hydrogen 2.584 N/A TYR 151.A N ASN 118.A O no hydrogen 3.284 N/A TYR 151.A OH HIS 115.A O no hydrogen 2.725 N/A ARG 152.A NE ASN 118.A OD1 no hydrogen 2.807 N/A ARG 152.A NH2 THR 116.A O no hydrogen 3.261 N/A ARG 152.A NH2 ASN 118.A OD1 no hydrogen 3.430 N/A ASP 153.A N GLN 158.A O no hydrogen 2.968 N/A ARG 155.A N ASP 153.A OD2 no hydrogen 3.042 N/A THR 156.A N ASP 153.A OD2 no hydrogen 2.894 N/A THR 156.A OG1 ASP 153.A OD2 no hydrogen 3.461 N/A GLN 158.A N THR 156.A OG1 no hydrogen 3.111 N/A HIS 159.A ND1 ILE 160.A O no hydrogen 2.798 N/A ILE 160.A N TYR 151.A O no hydrogen 2.782 N/A TYR 162.A OH GLU 164.A OE2 no hydrogen 3.363 N/A LYS 166.A N GLY 181.A O no hydrogen 3.018 N/A LYS 166.A NZ GLU 183.A OE2 no hydrogen 3.127 N/A THR 170.A OG1 ASP 123.A OD1 no hydrogen 3.476 N/A ARG 172.A NH1 TYR 173.A OH no hydrogen 3.155 N/A TYR 173.A N THR 170.A O no hydrogen 2.983 N/A ALA 174.A N ALA 171.A O no hydrogen 3.217 N/A SER 175.A OG ASP 188.A OD1 no hydrogen 2.960 N/A ILE 176.A N GLU 191.A OE2 no hydrogen 2.924 N/A HIS 179.A N SER 175.A O no hydrogen 3.329 N/A LEU 180.A N ILE 176.A O no hydrogen 3.294 N/A ILE 182.A N ASN 177.A O no hydrogen 2.943 N/A GLU 183.A N ARG 163.A O no hydrogen 3.303 N/A SER 185.A N ASP 188.A OD2 no hydrogen 2.769 N/A SER 185.A OG PHE 254.A O no hydrogen 2.694 N/A ARG 186.A NH2 GLU 255.A O no hydrogen 2.639 N/A ARG 187.A NH1 LEU 252.A O no hydrogen 3.000 N/A ASP 188.A N SER 185.A O no hydrogen 3.094 N/A MET 190.A N ARG 186.A O no hydrogen 3.199 N/A GLU 191.A N ARG 187.A O no hydrogen 2.874 N/A SER 192.A N ASP 188.A O no hydrogen 3.049 N/A SER 192.A OG TYR 173.A O no hydrogen 2.808 N/A SER 192.A OG ASP 188.A O no hydrogen 2.933 N/A LEU 193.A N ASP 189.A O no hydrogen 2.906 N/A GLY 194.A N MET 190.A O no hydrogen 3.109 N/A TYR 195.A N GLU 191.A O no hydrogen 3.188 N/A TYR 195.A OH GLU 191.A OE2 no hydrogen 2.465 N/A VAL 196.A N SER 192.A O no hydrogen 3.072 N/A LEU 197.A N LEU 193.A O no hydrogen 2.938 N/A MET 198.A N GLY 194.A O no hydrogen 3.065 N/A TYR 199.A N TYR 195.A O no hydrogen 2.889 N/A TYR 199.A OH GLU 85.A OE1 no hydrogen 2.586 N/A PHE 200.A N VAL 196.A O no hydrogen 3.263 N/A PHE 200.A N LEU 197.A O no hydrogen 2.880 N/A ASN 201.A N LEU 197.A O no hydrogen 2.983 N/A ARG 202.A N MET 198.A O no hydrogen 2.783 N/A ARG 202.A NE SER 204.A O no hydrogen 2.847 N/A ARG 202.A NH1 LEU 234.A O no hydrogen 2.595 N/A SER 204.A OG LEU 205.A O no hydrogen 3.493 N/A LEU 205.A N GLN 208.A OE1 no hydrogen 2.792 N/A TRP 207.A NE1 ARG 172.A O no hydrogen 2.900 N/A GLN 208.A N LEU 205.A O no hydrogen 3.374 N/A LYS 218.A N THR 214.A O no hydrogen 2.707 N/A TYR 219.A N LYS 215.A O no hydrogen 2.906 N/A GLU 220.A N LYS 216.A O no hydrogen 3.245 N/A LYS 221.A N GLN 217.A O no hydrogen 3.466 N/A SER 223.A N TYR 219.A O no hydrogen 2.762 N/A GLU 224.A N GLU 220.A O no hydrogen 3.201 N/A LYS 225.A N LYS 221.A O no hydrogen 2.560 N/A LYS 226.A N ILE 222.A O no hydrogen 2.753 N/A MET 227.A N SER 223.A O no hydrogen 3.047 N/A SER 228.A N GLU 224.A O no hydrogen 2.833 N/A SER 228.A N LYS 225.A O no hydrogen 3.195 N/A SER 228.A OG GLU 224.A O no hydrogen 3.315 N/A SER 228.A OG LYS 225.A O no hydrogen 2.452 N/A THR 229.A N LYS 225.A O no hydrogen 3.147 N/A THR 229.A N LYS 226.A O no hydrogen 3.068 N/A THR 229.A OG1 LYS 225.A O no hydrogen 3.122 N/A GLU 232.A N GLU 232.A OE1 no hydrogen 2.504 N/A LEU 234.A N PRO 230.A O no hydrogen 2.865 N/A CYS 235.A N VAL 231.A O no hydrogen 3.086 N/A CYS 235.A SG VAL 231.A O no hydrogen 3.367 N/A LYS 236.A N VAL 233.A O no hydrogen 3.204 N/A PHE 238.A N CYS 235.A O no hydrogen 3.099 N/A PHE 242.A N PRO 239.A O no hydrogen 3.185 N/A MET 244.A N ALA 240.A O no hydrogen 3.113 N/A TYR 245.A N GLU 241.A O no hydrogen 2.855 N/A TYR 245.A OH MET 190.A O no hydrogen 2.381 N/A LEU 246.A N PHE 242.A O no hydrogen 3.221 N/A ASN 247.A N ALA 243.A O no hydrogen 2.899 N/A ASN 247.A ND2 GLU 232.A OE2 no hydrogen 3.514 N/A TYR 248.A N MET 244.A O no hydrogen 3.013 N/A CYS 249.A N TYR 245.A O no hydrogen 2.944 N/A CYS 249.A SG TYR 245.A O no hydrogen 3.538 N/A ARG 250.A N LEU 246.A O no hydrogen 3.066 N/A LEU 252.A N CYS 249.A O no hydrogen 2.857 N/A ARG 253.A N GLU 256.A OE1 no hydrogen 2.958 N/A ARG 253.A NE GLU 255.A OE2 no hydrogen 2.821 N/A ARG 253.A NH2 GLU 255.A OE2 no hydrogen 3.393 N/A GLU 255.A N GLU 255.A OE1 no hydrogen 3.055 N/A GLU 256.A N ARG 253.A O no hydrogen 3.192 N/A ASP 259.A N TYR 248.A OH no hydrogen 2.809 N/A TYR 260.A OH HIS 115.A ND1 no hydrogen 2.749 N/A TYR 262.A N ASP 259.A OD1 no hydrogen 2.862 N/A LEU 263.A N ASP 259.A O no hydrogen 3.040 N/A ARG 264.A N TYR 260.A O no hydrogen 2.850 N/A ARG 264.A NH1 GLU 112.A OE1 no hydrogen 3.468 N/A ARG 264.A NH2 GLU 112.A OE1 no hydrogen 3.533 N/A GLN 265.A N MET 261.A O no hydrogen 2.863 N/A LEU 266.A N TYR 262.A O no hydrogen 3.023 N/A ARG 268.A N ARG 264.A O no hydrogen 2.956 N/A ILE 269.A N GLN 265.A O no hydrogen 2.740 N/A LEU 270.A N LEU 266.A O no hydrogen 3.076 N/A PHE 271.A N PHE 267.A O no hydrogen 2.584 N/A ARG 272.A N ARG 268.A O no hydrogen 2.956 N/A THR 273.A N ILE 269.A O no hydrogen 2.827 N/A THR 273.A OG1 ILE 269.A O no hydrogen 3.158 N/A LEU 274.A N LEU 270.A O no hydrogen 3.060 N/A ASN 275.A N ARG 272.A O no hydrogen 3.098 N/A HIS 276.A N PHE 271.A O no hydrogen 3.385 N/A THR 281.A N ASP 279.A OD1 no hydrogen 2.882 N/A THR 281.A OG1 ASP 279.A O no hydrogen 3.550 N/A THR 281.A OG1 ASP 279.A OD1 no hydrogen 3.279 N/A ASP 283.A N THR 99.A OG1 no hydrogen 2.963 N/A MET 286.A N PHE 282.A O no hydrogen 3.370 N/A MET 286.A N ASP 283.A O no hydrogen 3.122 N/A LEU 287.A N ASP 283.A O no hydrogen 3.323 N/A LYS 288.A N TRP 284.A O no hydrogen 3.237 N/A GLN 289.A N MET 286.A O no hydrogen 2.651 N/A