Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8g8x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 4.A N TYR 27.A OH no hydrogen 2.817 N/A HIS 7.A N GLU 4.A O no hydrogen 3.082 N/A LEU 8.A N GLU 5.A O no hydrogen 2.925 N/A LYS 9.A N ARG 26.A O no hydrogen 2.895 N/A LYS 9.A NZ ASP 28.A OD2 no hydrogen 3.275 N/A LEU 11.A N MET 24.A O no hydrogen 2.803 N/A GLN 12.A N MET 24.A O no hydrogen 3.257 N/A LEU 14.A N VAL 22.A O no hydrogen 2.820 N/A GLY 15.A N VAL 22.A O no hydrogen 3.188 N/A GLY 17.A N GLY 20.A O no hydrogen 2.809 N/A SER 21.A N LYS 42.A O no hydrogen 2.819 N/A VAL 22.A N GLY 15.A O no hydrogen 2.897 N/A GLU 23.A N VAL 40.A O no hydrogen 2.735 N/A MET 24.A N GLN 12.A O no hydrogen 2.835 N/A CYS 25.A N VAL 38.A O no hydrogen 2.879 N/A ARG 26.A N LYS 9.A O no hydrogen 2.801 N/A ARG 26.A NH1 GLY 35.A O no hydrogen 3.202 N/A TYR 27.A N GLU 36.A O no hydrogen 2.773 N/A ASP 28.A N HIS 7.A O no hydrogen 2.842 N/A GLN 31.A N ASP 28.A O no hydrogen 3.175 N/A ASP 32.A N ASP 28.A OD1 no hydrogen 3.471 N/A ASN 33.A N ASP 28.A OD2 no hydrogen 2.724 N/A THR 34.A OG1 ASP 32.A OD1 no hydrogen 2.600 N/A THR 34.A OG1 ASP 32.A OD2 no hydrogen 3.192 N/A GLY 35.A N ASP 28.A OD1 no hydrogen 3.174 N/A VAL 38.A N CYS 25.A O no hydrogen 2.770 N/A ALA 39.A N MET 82.A O no hydrogen 3.015 N/A VAL 40.A N GLU 23.A O no hydrogen 2.754 N/A LYS 41.A N LEU 80.A O no hydrogen 2.913 N/A LYS 41.A NZ GLU 55.A OE2 no hydrogen 2.663 N/A LYS 41.A NZ ASP 147.A OD1 no hydrogen 2.747 N/A LYS 42.A N SER 21.A O no hydrogen 2.916 N/A LYS 42.A NZ SER 21.A OG no hydrogen 3.395 N/A HIS 48.A N THR 45.A OG1 no hydrogen 2.639 N/A LEU 49.A N THR 45.A O no hydrogen 3.220 N/A ARG 50.A N GLU 46.A O no hydrogen 2.959 N/A ASP 51.A N GLU 47.A O no hydrogen 3.115 N/A PHE 52.A N HIS 48.A O no hydrogen 2.893 N/A GLU 53.A N LEU 49.A O no hydrogen 2.890 N/A ARG 54.A N ARG 50.A O no hydrogen 3.061 N/A ARG 54.A NH2 ASP 51.A OD1 no hydrogen 2.812 N/A GLU 55.A N ASP 51.A O no hydrogen 2.806 N/A ILE 56.A N PHE 52.A O no hydrogen 2.855 N/A GLU 57.A N GLU 53.A O no hydrogen 3.257 N/A ILE 58.A N ARG 54.A O no hydrogen 2.847 N/A LEU 59.A N GLU 55.A O no hydrogen 3.008 N/A LYS 60.A N ILE 56.A O no hydrogen 2.902 N/A SER 61.A N GLU 57.A O no hydrogen 3.051 N/A SER 61.A N ILE 58.A O no hydrogen 3.093 N/A SER 61.A OG GLU 57.A O no hydrogen 3.557 N/A SER 61.A OG ILE 58.A O no hydrogen 2.637 N/A SER 61.A OG TYR 125.A OH no hydrogen 2.496 N/A LEU 62.A N LEU 59.A O no hydrogen 2.932 N/A GLN 63.A N TYR 119.A OH no hydrogen 2.918 N/A ASN 66.A N HIS 64.A ND1 no hydrogen 2.955 N/A ASN 66.A ND2 VAL 143.A O no hydrogen 3.066 N/A ILE 67.A N HIS 64.A O no hydrogen 3.126 N/A VAL 68.A N ILE 145.A O no hydrogen 2.900 N/A LYS 69.A N GLU 83.A OE2 no hydrogen 2.896 N/A LYS 71.A N ILE 81.A O no hydrogen 2.902 N/A LYS 71.A NZ GLU 36.A OE2 no hydrogen 2.813 N/A GLY 72.A N ILE 81.A O no hydrogen 3.136 N/A CYS 74.A N LYS 79.A O no hydrogen 2.945 N/A CYS 74.A SG PHE 3.A O no hydrogen 3.409 N/A LYS 79.A N CYS 74.A O no hydrogen 2.806 N/A LYS 79.A NZ GLU 5.A OE1 no hydrogen 3.064 N/A LEU 80.A N LYS 41.A O no hydrogen 2.839 N/A ILE 81.A N GLY 72.A O no hydrogen 2.839 N/A MET 82.A N ALA 39.A O no hydrogen 2.789 N/A GLU 83.A N LYS 69.A O no hydrogen 3.007 N/A TYR 87.A N VAL 137.A O no hydrogen 3.391 N/A GLY 88.A N LEU 85.A O no hydrogen 3.367 N/A LEU 90.A N ILE 135.A O no hydrogen 2.723 N/A ARG 91.A N THR 132.A O no hydrogen 3.306 N/A ASP 92.A N SER 89.A OG no hydrogen 2.926 N/A TYR 93.A N SER 89.A O no hydrogen 2.832 N/A LEU 94.A N LEU 90.A O no hydrogen 2.833 N/A GLN 95.A N ARG 91.A O no hydrogen 3.173 N/A LYS 96.A N ASP 92.A O no hydrogen 2.989 N/A HIS 97.A N TYR 93.A O no hydrogen 2.792 N/A LYS 98.A NZ GLU 203.A OE1 no hydrogen 3.040 N/A ARG 100.A N HIS 97.A O no hydrogen 2.923 N/A ILE 101.A N LYS 98.A O no hydrogen 3.065 N/A LYS 105.A N ASP 102.A OD1 no hydrogen 2.946 N/A LYS 105.A NZ GLN 108.A OE1 no hydrogen 2.858 N/A LYS 105.A NZ GLU 140.A O no hydrogen 3.026 N/A LEU 106.A N ASP 102.A O no hydrogen 3.051 N/A LEU 107.A N HIS 103.A O no hydrogen 2.898 N/A GLN 108.A N ILE 104.A O no hydrogen 2.995 N/A TYR 109.A N LYS 105.A O no hydrogen 3.071 N/A TYR 109.A OH GLU 140.A O no hydrogen 2.890 N/A THR 110.A N LEU 106.A O no hydrogen 2.807 N/A THR 110.A OG1 LEU 106.A O no hydrogen 2.744 N/A SER 111.A N LEU 107.A O no hydrogen 2.991 N/A SER 111.A OG ASP 271.A OD1 no hydrogen 2.709 N/A GLN 112.A N GLN 108.A O no hydrogen 3.244 N/A GLN 112.A NE2 ASN 141.A O no hydrogen 2.998 N/A ILE 113.A N TYR 109.A O no hydrogen 2.949 N/A CYS 114.A N THR 110.A O no hydrogen 3.046 N/A CYS 114.A SG THR 110.A O no hydrogen 3.380 N/A LYS 115.A N SER 111.A O no hydrogen 2.989 N/A GLY 116.A N GLN 112.A O no hydrogen 2.911 N/A MET 117.A N ILE 113.A O no hydrogen 2.870 N/A GLU 118.A N CYS 114.A O no hydrogen 2.758 N/A TYR 119.A N LYS 115.A O no hydrogen 3.069 N/A LEU 120.A N GLY 116.A O no hydrogen 3.000 N/A GLY 121.A N MET 117.A O no hydrogen 2.944 N/A THR 122.A N GLU 118.A O no hydrogen 3.227 N/A THR 122.A OG1 TYR 119.A O no hydrogen 2.507 N/A LYS 123.A N LEU 120.A O no hydrogen 2.938 N/A LYS 123.A NZ SER 61.A O no hydrogen 3.562 N/A ARG 124.A N GLY 121.A O no hydrogen 2.821 N/A ARG 124.A NH1 GLU 159.A OE1 no hydrogen 3.333 N/A ARG 124.A NH1 GLU 159.A OE2 no hydrogen 3.388 N/A ARG 124.A NH2 PRO 155.A O no hydrogen 2.612 N/A ARG 124.A NH2 LYS 158.A O no hydrogen 3.002 N/A TYR 125.A N LEU 120.A O no hydrogen 3.184 N/A TYR 125.A OH SER 61.A OG no hydrogen 2.496 N/A ILE 126.A N LYS 152.A O no hydrogen 2.802 N/A HIS 127.A N ASP 187.A OD2 no hydrogen 2.790 N/A HIS 127.A NE2 ASP 147.A O no hydrogen 2.627 N/A ARG 128.A N ASP 187.A OD1 no hydrogen 2.935 N/A ARG 128.A NH1 GLU 163.A OE1 no hydrogen 3.008 N/A ARG 128.A NH2 LEU 150.A O no hydrogen 2.833 N/A ASP 129.A N HIS 127.A ND1 no hydrogen 3.009 N/A THR 132.A N GLU 197.A OE2 no hydrogen 3.120 N/A THR 132.A OG1 GLU 197.A OE1 no hydrogen 2.525 N/A ARG 133.A NH1 ASP 129.A OD2 no hydrogen 3.461 N/A ARG 133.A NH2 ASP 129.A OD1 no hydrogen 2.822 N/A ASN 134.A N ALA 131.A O no hydrogen 2.808 N/A ASN 134.A ND2 ASP 129.A O no hydrogen 2.803 N/A ILE 135.A N THR 132.A O no hydrogen 3.224 N/A LEU 136.A N LYS 144.A O no hydrogen 2.709 N/A VAL 137.A N GLY 88.A O no hydrogen 2.761 N/A GLU 138.A N ARG 142.A O no hydrogen 2.959 N/A ASN 139.A N ARG 142.A O no hydrogen 3.373 N/A ASN 141.A N ASN 139.A OD1 no hydrogen 2.988 N/A ARG 142.A N ASN 139.A O no hydrogen 3.247 N/A ARG 142.A NE ASP 65.A O no hydrogen 3.000 N/A ARG 142.A NH1 ASP 65.A O no hydrogen 3.223 N/A VAL 143.A N GLN 112.A OE1 no hydrogen 2.866 N/A LYS 144.A N LEU 136.A O no hydrogen 2.759 N/A LYS 144.A NZ GLU 83.A OE1 no hydrogen 3.489 N/A LYS 144.A NZ GLU 83.A OE2 no hydrogen 2.652 N/A ILE 145.A N ASN 66.A O no hydrogen 2.822 N/A GLY 146.A N ASN 134.A O no hydrogen 2.812 N/A GLY 149.A N ASP 147.A OD2 no hydrogen 2.951 N/A THR 151.A N PHE 148.A O no hydrogen 3.161 N/A THR 151.A OG1 HIS 127.A O no hydrogen 3.436 N/A THR 151.A OG1 PHE 148.A O no hydrogen 3.500 N/A LYS 152.A N ILE 126.A O no hydrogen 2.899 N/A LEU 154.A N ARG 124.A O no hydrogen 2.850 N/A LYS 158.A N PRO 155.A O no hydrogen 3.439 N/A LYS 158.A NZ ASP 157.A OD1 no hydrogen 3.259 N/A LYS 158.A NZ ASP 157.A OD2 no hydrogen 3.404 N/A VAL 161.A N SER 180.A O no hydrogen 3.168 N/A SER 167.A OG GLU 163.A OE1 no hydrogen 3.310 N/A TRP 171.A N PRO 168.A O no hydrogen 2.964 N/A TRP 171.A NE1 GLU 197.A OE2 no hydrogen 2.933 N/A TYR 172.A N ILE 169.A O no hydrogen 3.164 N/A GLU 175.A N GLU 175.A OE1 no hydrogen 2.729 N/A SER 176.A N ALA 173.A O no hydrogen 2.967 N/A SER 176.A OG LYS 181.A O no hydrogen 2.874 N/A LEU 177.A N ALA 173.A O no hydrogen 3.160 N/A THR 178.A N PRO 174.A O no hydrogen 2.884 N/A THR 178.A OG1 PRO 174.A O no hydrogen 3.192 N/A GLU 179.A N GLU 175.A O no hydrogen 3.027 N/A LYS 181.A N GLU 175.A O no hydrogen 3.225 N/A SER 183.A N SER 186.A OG no hydrogen 2.737 N/A SER 186.A N SER 183.A OG no hydrogen 3.031 N/A SER 186.A OG SER 183.A O no hydrogen 2.990 N/A ASP 187.A N SER 183.A O no hydrogen 2.975 N/A VAL 188.A N VAL 184.A O no hydrogen 2.923 N/A TRP 189.A N ALA 185.A O no hydrogen 3.026 N/A SER 190.A N SER 186.A O no hydrogen 2.930 N/A SER 190.A OG TRP 171.A O no hydrogen 2.678 N/A SER 190.A OG SER 186.A O no hydrogen 3.290 N/A PHE 191.A N ASP 187.A O no hydrogen 2.856 N/A GLY 192.A N VAL 188.A O no hydrogen 3.053 N/A VAL 193.A N TRP 189.A O no hydrogen 3.314 N/A VAL 194.A N SER 190.A O no hydrogen 2.955 N/A LEU 195.A N PHE 191.A O no hydrogen 2.933 N/A TYR 196.A N GLY 192.A O no hydrogen 2.994 N/A TYR 196.A OH LYS 206.A O no hydrogen 2.578 N/A GLU 197.A N VAL 193.A O no hydrogen 2.784 N/A LEU 198.A N VAL 194.A O no hydrogen 2.869 N/A PHE 199.A N LEU 195.A O no hydrogen 3.033 N/A THR 200.A N TYR 196.A O no hydrogen 2.898 N/A THR 200.A OG1 TYR 196.A O no hydrogen 2.827 N/A THR 200.A OG1 GLU 197.A O no hydrogen 3.049 N/A TYR 201.A N LEU 198.A O no hydrogen 2.891 N/A TYR 201.A OH ILE 101.A O no hydrogen 2.772 N/A ILE 202.A N GLU 197.A O no hydrogen 3.114 N/A GLU 203.A N THR 200.A O no hydrogen 3.074 N/A LYS 206.A N GLU 203.A O no hydrogen 2.987 N/A SER 207.A N LYS 204.A O no hydrogen 3.347 N/A SER 207.A OG LYS 204.A O no hydrogen 3.424 N/A ALA 210.A N SER 207.A OG no hydrogen 3.118 N/A GLU 211.A N SER 207.A O no hydrogen 2.911 N/A PHE 212.A N PRO 208.A O no hydrogen 3.025 N/A MET 213.A N PRO 209.A O no hydrogen 2.980 N/A ARG 214.A N ALA 210.A O no hydrogen 2.974 N/A ARG 214.A NH1 SER 205.A O no hydrogen 2.953 N/A ARG 214.A NH2 SER 205.A O no hydrogen 3.194 N/A MET 215.A N GLU 211.A O no hydrogen 2.967 N/A ILE 216.A N PHE 212.A O no hydrogen 2.795 N/A GLY 217.A N MET 213.A O no hydrogen 3.021 N/A SER 220.A OG THR 223.A OG1 no hydrogen 2.971 N/A THR 223.A N SER 220.A OG no hydrogen 2.980 N/A THR 223.A OG1 SER 220.A OG no hydrogen 2.971 N/A HIS 224.A N SER 220.A O no hydrogen 3.097 N/A LEU 225.A N ILE 221.A O no hydrogen 2.779 N/A ILE 226.A N VAL 222.A O no hydrogen 2.948 N/A GLU 227.A N THR 223.A O no hydrogen 3.192 N/A LEU 228.A N HIS 224.A O no hydrogen 2.822 N/A LEU 229.A N LEU 225.A O no hydrogen 2.826 N/A LYS 230.A N ILE 226.A O no hydrogen 2.875 N/A ASN 231.A N GLU 227.A O no hydrogen 2.965 N/A ASN 232.A N LEU 229.A O no hydrogen 3.045 N/A GLY 233.A N LEU 228.A O no hydrogen 2.926 N/A ARG 234.A NE TRP 253.A O no hydrogen 2.924 N/A ARG 234.A NH1 LEU 229.A O no hydrogen 2.895 N/A ARG 234.A NH1 GLY 233.A O no hydrogen 2.863 N/A ARG 234.A NH2 TRP 253.A O no hydrogen 2.723 N/A ARG 237.A NH1 CYS 241.A O no hydrogen 3.010 N/A ARG 237.A NH1 ASP 243.A OD1 no hydrogen 2.796 N/A ARG 237.A NH2 ASP 243.A OD1 no hydrogen 3.261 N/A CYS 241.A N PRO 238.A O no hydrogen 3.007 N/A CYS 241.A SG PRO 242.A O no hydrogen 3.643 N/A TYR 246.A N PRO 242.A O no hydrogen 3.034 N/A TYR 246.A OH LEU 235.A O no hydrogen 2.860 N/A MET 247.A N ASP 243.A O no hydrogen 2.914 N/A ILE 248.A N GLU 244.A O no hydrogen 3.134 N/A MET 249.A N ILE 245.A O no hydrogen 3.073 N/A THR 250.A N TYR 246.A O no hydrogen 2.995 N/A THR 250.A OG1 TYR 246.A O no hydrogen 3.493 N/A THR 250.A OG1 MET 247.A O no hydrogen 2.635 N/A GLU 251.A N MET 247.A O no hydrogen 3.037 N/A CYS 252.A N ILE 248.A O no hydrogen 3.010 N/A CYS 252.A SG VAL 188.A O no hydrogen 3.624 N/A CYS 252.A SG ILE 248.A O no hydrogen 3.291 N/A TRP 253.A N MET 249.A O no hydrogen 3.077 N/A ASN 254.A N GLU 251.A O no hydrogen 3.321 N/A ASN 255.A ND2 LEU 229.A O no hydrogen 3.506 N/A ASN 256.A N ASN 254.A OD1 no hydrogen 2.965 N/A ASN 258.A N ASN 256.A OD1 no hydrogen 2.881 N/A GLN 259.A N ASN 256.A O no hydrogen 3.043 N/A GLN 259.A NE2 ASN 254.A OD1 no hydrogen 3.052 N/A ARG 260.A N VAL 257.A O no hydrogen 3.310 N/A ARG 260.A NE ASN 254.A O no hydrogen 2.807 N/A ARG 260.A NH1 GLU 175.A OE2 no hydrogen 2.920 N/A ARG 260.A NH1 ALA 185.A O no hydrogen 2.964 N/A ARG 260.A NH2 GLU 175.A OE1 no hydrogen 2.929 N/A ARG 260.A NH2 ASN 254.A O no hydrogen 3.074 N/A ARG 264.A NE GLU 118.A OE2 no hydrogen 2.644 N/A ASP 265.A N SER 262.A OG no hydrogen 3.057 N/A LEU 266.A N SER 262.A O no hydrogen 2.975 N/A ALA 267.A N PHE 263.A O no hydrogen 2.904 N/A LEU 268.A N ARG 264.A O no hydrogen 3.173 N/A ARG 269.A N ASP 265.A O no hydrogen 2.926 N/A ARG 269.A NH1 GLU 251.A OE1 no hydrogen 2.852 N/A ARG 269.A NH2 GLU 251.A OE1 no hydrogen 3.535 N/A ARG 269.A NH2 GLU 251.A OE2 no hydrogen 2.843 N/A VAL 270.A N LEU 266.A O no hydrogen 2.850 N/A ASP 271.A N ALA 267.A O no hydrogen 2.856 N/A GLN 272.A N LEU 268.A O no hydrogen 3.021 N/A ILE 273.A N ARG 269.A O no hydrogen 3.003 N/A ARG 274.A N VAL 270.A O no hydrogen 2.923 N/A ARG 274.A NE ILE 104.A O no hydrogen 3.065 N/A ASP 275.A N ASP 271.A O no hydrogen 3.044 N/A ASN 276.A N GLN 272.A O no hydrogen 2.899 N/A MET 277.A N ILE 273.A O no hydrogen 3.067 N/A MET 277.A N ARG 274.A O no hydrogen 3.144 N/A