Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8gvv_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 3.A ND2 LEU 243.A O no hydrogen 3.384 N/A ASP 4.A N ALA 1.A O no hydrogen 2.840 N/A ARG 6.A N THR 2.A O no hydrogen 3.419 N/A ARG 6.A NH1 ASN 3.A OD1 no hydrogen 2.896 N/A ARG 6.A NH2 GLU 247.A O no hydrogen 2.503 N/A CYS 7.A N ASN 3.A O no hydrogen 2.931 N/A CYS 7.A SG GLU 11.A OE1 no hydrogen 3.577 N/A CYS 7.A SG ILE 280.A O no hydrogen 4.041 N/A LYS 8.A N ASP 4.A O no hydrogen 3.082 N/A LYS 8.A NZ ASP 4.A O no hydrogen 2.484 N/A ILE 9.A N GLU 5.A O no hydrogen 3.164 N/A LEU 10.A N ARG 6.A O no hydrogen 2.956 N/A GLU 11.A N CYS 7.A O no hydrogen 2.808 N/A GLN 12.A N LYS 8.A O no hydrogen 2.809 N/A ARG 13.A N ILE 9.A O no hydrogen 2.947 N/A ARG 13.A NE TYR 276.A OH no hydrogen 3.071 N/A ARG 13.A NH2 TYR 276.A OH no hydrogen 3.317 N/A LEU 14.A N LEU 10.A O no hydrogen 3.026 N/A GLU 15.A N GLU 11.A O no hydrogen 2.724 N/A GLN 16.A N GLN 12.A O no hydrogen 2.864 N/A GLY 17.A N LEU 14.A O no hydrogen 2.941 N/A MET 18.A N ARG 13.A O no hydrogen 2.973 N/A TYR 23.A N VAL 19.A O no hydrogen 2.945 N/A TYR 23.A OH VAL 266.A O no hydrogen 3.033 N/A GLU 24.A N PHE 20.A O no hydrogen 2.824 N/A ILE 26.A N TYR 23.A O no hydrogen 3.143 N/A LYS 28.A NZ MET 264.A O no hydrogen 3.055 N/A LYS 29.A NZ GLY 34.A O no hydrogen 2.779 N/A ARG 30.A N TYR 56.A OH no hydrogen 3.081 N/A ARG 30.A NE GLN 260.A O no hydrogen 2.758 N/A ARG 30.A NH1 ASP 33.A O no hydrogen 2.595 N/A ARG 30.A NH1 ASP 58.A OD1 no hydrogen 3.065 N/A ARG 30.A NH1 ASP 58.A OD2 no hydrogen 3.463 N/A ARG 30.A NH2 ASP 58.A OD1 no hydrogen 2.936 N/A ARG 30.A NH2 GLN 260.A O no hydrogen 2.910 N/A GLU 35.A N GLU 35.A OE1 no hydrogen 2.906 N/A CYS 36.A SG GLY 34.A O no hydrogen 3.673 N/A CYS 36.A SG LEU 54.A O no hydrogen 4.026 N/A CYS 36.A SG PRO 55.A O no hydrogen 3.268 N/A SER 37.A N ASP 57.A OD2 no hydrogen 3.033 N/A SER 37.A OG ASP 57.A OD2 no hydrogen 2.747 N/A THR 38.A N ASP 57.A OD1 no hydrogen 3.078 N/A THR 38.A OG1 ASP 57.A OD1 no hydrogen 3.508 N/A ARG 40.A N CYS 36.A O no hydrogen 2.961 N/A ARG 40.A N SER 37.A O no hydrogen 3.097 N/A LEU 41.A N THR 38.A O no hydrogen 3.110 N/A ASN 44.A N LEU 41.A O no hydrogen 2.868 N/A ASN 44.A ND2 THR 38.A O no hydrogen 2.973 N/A ASN 44.A ND2 THR 71.A OG1 no hydrogen 3.214 N/A ALA 45.A N PRO 42.A O no hydrogen 3.129 N/A ARG 47.A N ASN 44.A O no hydrogen 2.909 N/A ARG 47.A NH1 ASN 44.A OD1 no hydrogen 2.791 N/A ASN 48.A N ALA 45.A O no hydrogen 3.335 N/A ASN 48.A ND2 ALA 39.A O no hydrogen 3.014 N/A ASN 48.A ND2 GLN 51.A OE1 no hydrogen 3.082 N/A ARG 49.A N GLN 94.A OE1 no hydrogen 2.994 N/A ARG 49.A NE GLY 95.A O no hydrogen 2.844 N/A ARG 49.A NH1 GLU 128.A OE1 no hydrogen 3.514 N/A ARG 49.A NH2 GLY 95.A O no hydrogen 3.174 N/A ARG 49.A NH2 PRO 96.A O no hydrogen 2.901 N/A ARG 49.A NH2 GLU 128.A OE1 no hydrogen 2.956 N/A GLN 51.A NE2 ALA 45.A O no hydrogen 2.892 N/A GLN 51.A NE2 ASN 48.A O no hydrogen 3.560 N/A VAL 53.A N PHE 50.A O no hydrogen 3.175 N/A TYR 56.A OH ARG 259.A O no hydrogen 2.881 N/A ASP 57.A N GLU 35.A O no hydrogen 2.868 N/A VAL 59.A N TYR 56.A O no hydrogen 3.290 N/A ARG 60.A NH1 THR 71.A O no hydrogen 3.383 N/A ARG 60.A NH1 GLY 72.A O no hydrogen 3.188 N/A ARG 60.A NH2 THR 71.A O no hydrogen 3.006 N/A VAL 61.A N ALA 76.A O no hydrogen 3.095 N/A LEU 63.A N GLY 72.A O no hydrogen 3.004 N/A VAL 64.A N GLU 110.A OE1 no hydrogen 3.068 N/A THR 66.A N ASN 69.A O no hydrogen 3.030 N/A ASN 69.A N THR 66.A O no hydrogen 3.054 N/A ASN 69.A ND2 TYR 73.A O no hydrogen 2.955 N/A ASN 69.A ND2 ASP 103.A OD1 no hydrogen 2.932 N/A THR 71.A OG1 ASN 44.A OD1 no hydrogen 3.567 N/A GLY 72.A N ASN 69.A O no hydrogen 2.988 N/A TYR 73.A N ASN 69.A OD1 no hydrogen 2.928 N/A TYR 73.A OH ASN 48.A OD1 no hydrogen 2.568 N/A ASN 75.A ND2 ASN 48.A OD1 no hydrogen 3.022 N/A ASN 75.A ND2 VAL 53.A O no hydrogen 2.801 N/A SER 77.A N ALA 92.A O no hydrogen 2.894 N/A HIS 78.A N VAL 59.A O no hydrogen 2.831 N/A ILE 79.A N TYR 90.A O no hydrogen 2.792 N/A LYS 80.A NZ HIS 78.A ND1 no hydrogen 3.387 N/A VAL 81.A N TRP 88.A O no hydrogen 3.076 N/A VAL 83.A N ILE 86.A O no hydrogen 2.987 N/A ILE 86.A N VAL 83.A O no hydrogen 3.283 N/A TRP 88.A N VAL 81.A O no hydrogen 2.562 N/A TYR 90.A N ILE 79.A O no hydrogen 2.821 N/A TYR 90.A OH GLU 237.A OE1 no hydrogen 2.615 N/A ILE 91.A N LEU 219.A O no hydrogen 2.881 N/A ALA 92.A N SER 77.A O no hydrogen 3.033 N/A THR 93.A N VAL 221.A O no hydrogen 3.002 N/A THR 93.A OG1 ASN 75.A O no hydrogen 2.696 N/A GLN 94.A N ASN 75.A O no hydrogen 3.349 N/A GLN 94.A NE2 ARG 47.A O no hydrogen 3.028 N/A GLY 95.A N SER 224.A O no hydrogen 2.822 N/A LEU 97.A N THR 100.A OG1 no hydrogen 2.884 N/A ASN 99.A ND2 GLU 46.A O no hydrogen 3.208 N/A THR 100.A N LEU 97.A O no hydrogen 2.992 N/A THR 100.A OG1 LEU 97.A O no hydrogen 3.455 N/A CYS 101.A SG LEU 97.A O no hydrogen 3.531 N/A CYS 101.A SG GLN 98.A O no hydrogen 3.792 N/A PHE 104.A N THR 100.A O no hydrogen 2.832 N/A TRP 105.A N CYS 101.A O no hydrogen 2.998 N/A TRP 105.A NE1 TYR 133.A O no hydrogen 2.927 N/A GLN 106.A N GLN 102.A O no hydrogen 2.835 N/A GLN 106.A NE2 VAL 64.A O no hydrogen 2.976 N/A GLN 106.A NE2 GLU 110.A OE1 no hydrogen 3.524 N/A GLN 106.A NE2 GLU 110.A OE2 no hydrogen 2.781 N/A MET 107.A N ASP 103.A O no hydrogen 2.948 N/A VAL 108.A N PHE 104.A O no hydrogen 2.948 N/A TRP 109.A N TRP 105.A O no hydrogen 2.935 N/A GLU 110.A N GLN 106.A O no hydrogen 2.840 N/A GLN 111.A N MET 107.A O no hydrogen 2.943 N/A GLY 112.A N TRP 109.A O no hydrogen 3.132 N/A ILE 113.A N VAL 108.A O no hydrogen 2.975 N/A ILE 116.A N TRP 178.A O no hydrogen 2.813 N/A ALA 117.A N LEU 220.A O no hydrogen 2.667 N/A MET 118.A N LEU 180.A O no hydrogen 2.863 N/A VAL 119.A N HIS 222.A O no hydrogen 2.818 N/A THR 120.A OG1 ALA 121.A O no hydrogen 2.832 N/A THR 120.A OG1 GLU 124.A OE2 no hydrogen 3.306 N/A ALA 121.A N GLU 124.A OE2 no hydrogen 3.194 N/A GLU 124.A N ARG 127.A O no hydrogen 2.987 N/A GLY 126.A N GLU 123.A OE2 no hydrogen 3.229 N/A ARG 127.A N GLU 124.A O no hydrogen 3.040 N/A ARG 127.A NH2 GLU 187.A OE1 no hydrogen 3.520 N/A LYS 129.A N GLU 122.A O no hydrogen 2.756 N/A LYS 129.A NZ GLU 124.A OE1 no hydrogen 2.895 N/A LYS 129.A NZ GLU 187.A OE1 no hydrogen 2.824 N/A SER 130.A N GLU 122.A O no hydrogen 3.130 N/A SER 130.A OG PHE 131.A O no hydrogen 3.082 N/A PHE 131.A N PRO 96.A O no hydrogen 2.838 N/A ARG 132.A NE TRP 134.A O no hydrogen 2.810 N/A ARG 132.A NH1 GLU 122.A OE2 no hydrogen 2.861 N/A ARG 132.A NH2 PRO 135.A O no hydrogen 3.083 N/A TYR 133.A OH HIS 222.A NE2 no hydrogen 2.833 N/A ARG 136.A NH1 GLU 122.A OE1 no hydrogen 2.855 N/A GLY 138.A N ASN 139.A OD1 no hydrogen 2.713 N/A THR 140.A OG1 ILE 148.A O no hydrogen 3.022 N/A THR 140.A OG1 THR 149.A OG1 no hydrogen 3.387 N/A VAL 141.A N ILE 148.A O no hydrogen 2.830 N/A TYR 143.A N PHE 146.A O no hydrogen 2.793 N/A ARG 145.A NE HIS 168.A NE2 no hydrogen 3.642 N/A ARG 145.A NH2 GLU 110.A OE2 no hydrogen 3.338 N/A PHE 146.A N TYR 143.A O no hydrogen 3.125 N/A LYS 147.A N LYS 167.A O no hydrogen 2.906 N/A ILE 148.A N VAL 141.A O no hydrogen 2.744 N/A THR 149.A N LYS 165.A O no hydrogen 2.781 N/A THR 149.A OG1 THR 140.A OG1 no hydrogen 3.387 N/A THR 150.A N ASN 139.A O no hydrogen 2.844 N/A THR 150.A OG1 PRO 135.A O no hydrogen 2.820 N/A ARG 151.A N GLY 163.A O no hydrogen 2.859 N/A THR 154.A N THR 161.A O no hydrogen 2.810 N/A SER 156.A N TYR 159.A O no hydrogen 2.758 N/A GLY 157.A N ASP 155.A OD1 no hydrogen 2.811 N/A CYS 158.A N SER 156.A O no hydrogen 2.992 N/A CYS 158.A SG ASP 193.A OD2 no hydrogen 3.748 N/A ALA 160.A N GLN 181.A O no hydrogen 2.931 N/A THR 161.A N THR 154.A O no hydrogen 2.868 N/A THR 162.A N HIS 179.A O no hydrogen 2.749 N/A GLY 163.A N PHE 152.A O no hydrogen 3.031 N/A LEU 164.A N VAL 177.A O no hydrogen 2.946 N/A LYS 165.A N THR 149.A O no hydrogen 2.866 N/A MET 166.A N ARG 175.A O no hydrogen 2.813 N/A LYS 167.A N LYS 147.A O no hydrogen 2.746 N/A LYS 167.A NZ GLY 172.A O no hydrogen 3.111 N/A LYS 167.A NZ GLU 174.A OE2 no hydrogen 2.968 N/A HIS 168.A N GLN 173.A O no hydrogen 2.808 N/A LEU 169.A N ARG 145.A O no hydrogen 2.747 N/A LEU 170.A N HIS 168.A ND1 no hydrogen 3.273 N/A THR 171.A OG1 GLN 173.A OE1 no hydrogen 2.570 N/A GLY 172.A N HIS 168.A O no hydrogen 2.735 N/A GLN 173.A N THR 171.A OG1 no hydrogen 3.011 N/A ARG 175.A N MET 166.A O no hydrogen 2.827 N/A ARG 175.A NH1 VAL 108.A O no hydrogen 2.879 N/A ARG 175.A NH1 ILE 113.A O no hydrogen 2.905 N/A ARG 175.A NH2 TRP 109.A O no hydrogen 2.900 N/A VAL 177.A N LEU 164.A O no hydrogen 2.963 N/A TRP 178.A N ALA 114.A O no hydrogen 2.868 N/A HIS 179.A N THR 162.A O no hydrogen 2.947 N/A HIS 179.A NE2 TYR 133.A OH no hydrogen 2.999 N/A LEU 180.A N ILE 116.A O no hydrogen 2.832 N/A GLN 181.A N ALA 160.A O no hydrogen 2.857 N/A GLN 181.A NE2 THR 120.A O no hydrogen 3.149 N/A TYR 182.A N MET 118.A O no hydrogen 2.945 N/A THR 183.A N CYS 158.A O no hydrogen 3.193 N/A THR 183.A OG1 CYS 158.A O no hydrogen 3.326 N/A TRP 185.A NE1 GLY 189.A O no hydrogen 2.966 N/A HIS 188.A ND1 GLN 267.A OE1 no hydrogen 3.118 N/A GLY 189.A N PRO 186.A O no hydrogen 3.037 N/A CYS 190.A SG CYS 270.A O no hydrogen 3.146 N/A GLY 196.A N ASP 193.A OD1 no hydrogen 2.905 N/A PHE 197.A N ASP 193.A O no hydrogen 2.978 N/A LEU 198.A N LEU 194.A O no hydrogen 3.026 N/A SER 199.A N LYS 195.A O no hydrogen 3.018 N/A SER 199.A OG GLY 196.A O no hydrogen 2.693 N/A TYR 200.A N GLY 196.A O no hydrogen 2.968 N/A TYR 200.A OH LEU 180.A O no hydrogen 2.812 N/A LEU 201.A N PHE 197.A O no hydrogen 2.887 N/A GLU 202.A N LEU 198.A O no hydrogen 2.875 N/A GLU 203.A N SER 199.A O no hydrogen 3.025 N/A ILE 204.A N TYR 200.A O no hydrogen 3.007 N/A GLN 205.A N LEU 201.A O no hydrogen 2.949 N/A SER 206.A N GLU 202.A O no hydrogen 2.921 N/A SER 206.A OG GLU 202.A O no hydrogen 3.121 N/A VAL 207.A N GLU 203.A O no hydrogen 2.916 N/A ARG 208.A N ILE 204.A O no hydrogen 2.947 N/A ARG 208.A NH1 GLU 237.A OE2 no hydrogen 2.888 N/A ARG 208.A NH2 GLU 237.A OE1 no hydrogen 2.807 N/A ARG 208.A NH2 GLU 237.A OE2 no hydrogen 3.459 N/A ARG 209.A N GLN 205.A O no hydrogen 3.091 N/A HIS 210.A N SER 206.A O no hydrogen 3.012 N/A THR 211.A N VAL 207.A O no hydrogen 2.909 N/A THR 211.A OG1 VAL 207.A O no hydrogen 2.717 N/A THR 211.A OG1 ARG 208.A O no hydrogen 3.272 N/A ASN 212.A N ARG 208.A O no hydrogen 2.972 N/A SER 213.A N ARG 209.A O no hydrogen 3.022 N/A SER 213.A OG ARG 209.A O no hydrogen 3.071 N/A THR 214.A N HIS 210.A O no hydrogen 3.296 N/A THR 214.A N THR 211.A O no hydrogen 3.321 N/A THR 214.A OG1 THR 211.A O no hydrogen 3.102 N/A LEU 219.A N ASP 89.A O no hydrogen 3.231 N/A LEU 220.A N ILE 115.A O no hydrogen 3.246 N/A VAL 221.A N ILE 91.A O no hydrogen 2.843 N/A HIS 222.A N ALA 117.A O no hydrogen 2.907 N/A HIS 222.A ND1 SER 223.A O no hydrogen 2.943 N/A HIS 222.A NE2 TYR 133.A OH no hydrogen 2.833 N/A SER 223.A OG THR 230.A OG1 no hydrogen 2.777 N/A SER 224.A OG LYS 129.A O no hydrogen 2.677 N/A GLY 226.A N SER 223.A OG no hydrogen 3.004 N/A ARG 229.A NH1 GLU 124.A OE2 no hydrogen 2.966 N/A ARG 229.A NH1 TRP 185.A O no hydrogen 2.765 N/A THR 230.A OG1 SER 223.A OG no hydrogen 2.777 N/A GLY 231.A N VAL 227.A O no hydrogen 3.065 N/A VAL 232.A N GLY 228.A O no hydrogen 3.047 N/A VAL 233.A N ARG 229.A O no hydrogen 3.099 N/A ILE 234.A N THR 230.A O no hydrogen 3.141 N/A LEU 235.A N GLY 231.A O no hydrogen 2.851 N/A SER 236.A N VAL 232.A O no hydrogen 2.979 N/A SER 236.A OG VAL 232.A O no hydrogen 2.796 N/A GLU 237.A N VAL 233.A O no hydrogen 3.000 N/A ILE 238.A N ILE 234.A O no hydrogen 3.008 N/A MET 239.A N LEU 235.A O no hydrogen 2.900 N/A ILE 240.A N SER 236.A O no hydrogen 2.909 N/A ALA 241.A N GLU 237.A O no hydrogen 3.196 N/A CYS 242.A N ILE 238.A O no hydrogen 3.052 N/A CYS 242.A SG SER 84.A OG no hydrogen 3.745 N/A CYS 242.A SG ILE 238.A O no hydrogen 3.476 N/A LEU 243.A N ILE 240.A O no hydrogen 3.116 N/A HIS 245.A N CYS 242.A O no hydrogen 3.248 N/A GLU 247.A N HIS 245.A O no hydrogen 2.453 N/A ARG 253.A N ASP 250.A OD1 no hydrogen 3.241 N/A ARG 253.A NE ASP 250.A OD2 no hydrogen 3.147 N/A VAL 254.A N ASP 250.A O no hydrogen 3.055 N/A LEU 255.A N ILE 251.A O no hydrogen 2.869 N/A ASP 256.A N PRO 252.A O no hydrogen 2.894 N/A MET 257.A N ARG 253.A O no hydrogen 2.971 N/A LEU 258.A N VAL 254.A O no hydrogen 2.917 N/A ARG 259.A N LEU 255.A O no hydrogen 2.907 N/A ARG 259.A NE LEU 265.A O no hydrogen 2.854 N/A ARG 259.A NH1 LEU 27.A O no hydrogen 3.047 N/A ARG 259.A NH2 LEU 265.A O no hydrogen 3.031 N/A ARG 259.A NH2 VAL 266.A O no hydrogen 2.881 N/A GLN 260.A N ASP 256.A O no hydrogen 3.142 N/A GLN 260.A N MET 257.A O no hydrogen 3.258 N/A GLN 260.A NE2 ASP 256.A O no hydrogen 3.171 N/A GLN 261.A N LEU 258.A O no hydrogen 2.902 N/A GLN 261.A NE2 MET 257.A O no hydrogen 3.040 N/A ARG 262.A N LEU 258.A O no hydrogen 3.026 N/A ARG 262.A NE GLY 226.A O no hydrogen 2.913 N/A ARG 262.A NH1 ASN 75.A OD1 no hydrogen 3.016 N/A ARG 262.A NH1 SER 77.A OG no hydrogen 2.890 N/A ARG 262.A NH2 ASN 75.A OD1 no hydrogen 2.857 N/A ARG 262.A NH2 ALA 225.A O no hydrogen 3.268 N/A MET 264.A N LYS 28.A O no hydrogen 2.784 N/A VAL 266.A N VAL 227.A O no hydrogen 2.880 N/A THR 268.A N GLN 271.A OE1 no hydrogen 3.246 N/A THR 268.A OG1 HIS 188.A O no hydrogen 3.143 N/A CYS 270.A SG HIS 188.A O no hydrogen 3.512 N/A CYS 270.A SG THR 268.A OG1 no hydrogen 3.261 N/A GLN 271.A N THR 268.A OG1 no hydrogen 3.307 N/A GLN 271.A NE2 GLY 189.A O no hydrogen 3.186 N/A TYR 272.A N THR 268.A O no hydrogen 3.150 N/A TYR 272.A OH GLU 22.A OE2 no hydrogen 2.698 N/A THR 273.A N LEU 269.A O no hydrogen 2.687 N/A THR 273.A OG1 LEU 269.A O no hydrogen 3.455 N/A THR 273.A OG1 CYS 270.A O no hydrogen 2.933 N/A PHE 274.A N CYS 270.A O no hydrogen 2.745 N/A VAL 275.A N GLN 271.A O no hydrogen 3.195 N/A TYR 276.A N TYR 272.A O no hydrogen 3.366 N/A TYR 276.A OH GLU 22.A OE1 no hydrogen 3.195 N/A TYR 276.A OH GLU 22.A OE2 no hydrogen 2.523 N/A ARG 277.A N THR 273.A O no hydrogen 3.028 N/A VAL 278.A N PHE 274.A O no hydrogen 2.823 N/A LEU 279.A N VAL 275.A O no hydrogen 3.019 N/A ILE 280.A N TYR 276.A O no hydrogen 2.892 N/A GLN 281.A N ARG 277.A O no hydrogen 2.978 N/A GLN 281.A NE2 GLN 281.A O no hydrogen 3.089 N/A GLN 281.A NE2 SER 285.A OG no hydrogen 3.074 N/A PHE 282.A N VAL 278.A O no hydrogen 2.847 N/A LEU 283.A N LEU 279.A O no hydrogen 2.871 N/A LYS 284.A N ILE 280.A O no hydrogen 2.669 N/A SER 285.A N GLN 281.A O no hydrogen 3.143 N/A SER 285.A N PHE 282.A O no hydrogen 3.273 N/A SER 285.A OG GLN 281.A O no hydrogen 2.991 N/A SER 286.A N LEU 283.A O no hydrogen 3.288 N/A SER 286.A OG PHE 282.A O no hydrogen 3.562 N/A