Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8had_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 6.A N ASP 4.A O no hydrogen 2.712 N/A SER 6.A OG VAL 324.A O no hydrogen 3.481 N/A LEU 7.A N LEU 323.A O no hydrogen 3.256 N/A LYS 8.A NZ ASP 12.A OD1 no hydrogen 3.475 N/A ASN 9.A ND2 SER 6.A O no hydrogen 3.442 N/A ASN 9.A ND2 ASN 238.A OD1 no hydrogen 2.786 N/A ILE 10.A N LEU 7.A O no hydrogen 3.061 N/A ASP 12.A N LYS 8.A O no hydrogen 2.886 N/A GLN 13.A N ASN 9.A O no hydrogen 3.041 N/A GLN 13.A NE2 PRO 203.A O no hydrogen 2.979 N/A THR 15.A OG1 THR 204.A O no hydrogen 2.800 N/A LEU 16.A N GLN 13.A O no hydrogen 3.343 N/A GLN 17.A N LYS 205.A O no hydrogen 2.668 N/A TRP 18.A N LYS 205.A O no hydrogen 2.766 N/A VAL 19.A N VAL 124.A O no hydrogen 2.931 N/A PHE 20.A N THR 207.A O no hydrogen 3.095 N/A VAL 21.A N PHE 126.A O no hydrogen 2.926 N/A GLY 22.A N VAL 209.A O no hydrogen 3.033 N/A LYS 24.A NZ GLY 25.A O no hydrogen 3.042 N/A LYS 29.A NZ LYS 24.A O no hydrogen 3.161 N/A THR 30.A OG1 ASP 127.A OD2 no hydrogen 3.284 N/A THR 32.A N GLY 28.A O no hydrogen 2.972 N/A THR 32.A OG1 GLY 28.A O no hydrogen 2.902 N/A SER 33.A N LYS 29.A O no hydrogen 2.905 N/A SER 33.A OG LYS 29.A O no hydrogen 2.732 N/A SER 33.A OG ASP 127.A OD1 no hydrogen 3.448 N/A CYS 34.A N THR 30.A O no hydrogen 2.908 N/A CYS 34.A SG THR 30.A O no hydrogen 3.157 N/A CYS 35.A N THR 31.A O no hydrogen 2.921 N/A CYS 35.A SG THR 31.A O no hydrogen 3.140 N/A CYS 35.A SG LEU 316.A O no hydrogen 3.468 N/A LEU 36.A N THR 32.A O no hydrogen 2.893 N/A GLY 37.A N SER 33.A O no hydrogen 2.915 N/A VAL 38.A N CYS 34.A O no hydrogen 2.904 N/A GLN 39.A N CYS 35.A O no hydrogen 2.931 N/A LEU 40.A N LEU 36.A O no hydrogen 2.868 N/A ALA 41.A N GLY 37.A O no hydrogen 2.915 N/A LYS 42.A N GLN 39.A O no hydrogen 3.199 N/A LYS 42.A NZ GLN 39.A OE1 no hydrogen 3.238 N/A ARG 44.A N LEU 40.A O no hydrogen 2.845 N/A ARG 44.A NH1 LEU 16.A O no hydrogen 2.785 N/A ARG 44.A NH2 LEU 16.A O no hydrogen 3.284 N/A VAL 47.A N ASN 78.A O no hydrogen 2.673 N/A LEU 48.A N VAL 123.A O no hydrogen 2.957 N/A LEU 49.A N CYS 80.A O no hydrogen 2.853 N/A VAL 50.A N VAL 125.A O no hydrogen 2.887 N/A SER 51.A N MET 82.A O no hydrogen 2.929 N/A SER 51.A OG GLU 83.A OE1 no hydrogen 3.080 N/A SER 51.A OG GLU 83.A OE2 no hydrogen 2.992 N/A SER 51.A OG ASP 127.A OD2 no hydrogen 3.509 N/A THR 52.A N ASP 127.A O no hydrogen 2.969 N/A ALA 61.A N ASN 57.A O no hydrogen 2.890 N/A PHE 62.A N LEU 58.A O no hydrogen 2.933 N/A CYS 63.A SG ASP 60.A O no hydrogen 3.744 N/A GLN 64.A N SER 59.A O no hydrogen 3.092 N/A GLN 64.A NE2 PRO 72.A O no hydrogen 3.606 N/A ILE 66.A N SER 59.A OG no hydrogen 3.285 N/A GLY 67.A N THR 71.A OG1 no hydrogen 3.090 N/A ARG 68.A NH1 ARG 68.A O no hydrogen 2.678 N/A THR 71.A N ALA 81.A O no hydrogen 2.788 N/A THR 71.A OG1 GLU 69.A O no hydrogen 3.107 N/A ILE 73.A N LEU 79.A O no hydrogen 2.648 N/A HIS 74.A N GLN 64.A OE1 no hydrogen 3.372 N/A PHE 76.A N ILE 73.A O no hydrogen 3.072 N/A ASN 78.A ND2 ALA 41.A O no hydrogen 2.586 N/A CYS 80.A N VAL 47.A O no hydrogen 2.953 N/A ALA 81.A N THR 71.A O no hydrogen 3.084 N/A GLU 83.A N GLY 67.A O no hydrogen 3.311 N/A ILE 84.A N SER 51.A O no hydrogen 3.232 N/A GLN 91.A N ASP 87.A O no hydrogen 2.888 N/A GLN 91.A NE2 ASP 95.A OD1 no hydrogen 3.027 N/A MET 92.A N VAL 88.A O no hydrogen 2.936 N/A PHE 93.A N PHE 89.A O no hydrogen 2.890 N/A ASN 94.A N GLY 90.A O no hydrogen 2.887 N/A ASN 94.A ND2 GLY 90.A O no hydrogen 2.889 N/A ASP 95.A N GLN 91.A O no hydrogen 2.905 N/A LEU 96.A N MET 92.A O no hydrogen 2.922 N/A GLN 97.A N PHE 93.A O no hydrogen 2.893 N/A ASN 98.A N ASN 94.A O no hydrogen 2.885 N/A SER 99.A N ASP 95.A O no hydrogen 2.902 N/A SER 99.A OG ASP 95.A O no hydrogen 3.317 N/A ILE 100.A N LEU 96.A O no hydrogen 2.736 N/A ILE 103.A N ILE 100.A O no hydrogen 3.482 N/A ALA 106.A N GLY 102.A O no hydrogen 3.059 N/A MET 107.A N ILE 103.A O no hydrogen 2.924 N/A SER 108.A N ASP 104.A O no hydrogen 2.924 N/A SER 108.A OG ASP 104.A O no hydrogen 3.051 N/A PHE 109.A N GLU 105.A O no hydrogen 2.887 N/A SER 110.A N ALA 106.A O no hydrogen 2.892 N/A GLU 111.A N MET 107.A O no hydrogen 2.943 N/A LEU 112.A N SER 108.A O no hydrogen 2.921 N/A MET 113.A N PHE 109.A O no hydrogen 2.869 N/A LYS 114.A N SER 110.A O no hydrogen 2.924 N/A LYS 114.A NZ GLU 111.A OE2 no hydrogen 3.020 N/A GLN 115.A N GLU 111.A O no hydrogen 2.931 N/A GLN 115.A NE2 GLU 69.A OE2 no hydrogen 3.111 N/A VAL 116.A N LEU 112.A O no hydrogen 2.906 N/A GLN 117.A N MET 113.A O no hydrogen 2.885 N/A GLN 118.A N LYS 114.A O no hydrogen 2.938 N/A LEU 119.A N GLN 115.A O no hydrogen 2.913 N/A LEU 119.A N VAL 116.A O no hydrogen 3.124 N/A ASP 122.A N LYS 46.A O no hydrogen 3.188 N/A VAL 124.A N GLN 17.A O no hydrogen 3.084 N/A VAL 125.A N LEU 48.A O no hydrogen 2.865 N/A PHE 126.A N VAL 19.A O no hydrogen 2.845 N/A ASP 127.A N VAL 50.A O no hydrogen 2.892 N/A THR 128.A N VAL 21.A O no hydrogen 3.199 N/A THR 128.A OG1 VAL 21.A O no hydrogen 2.959 N/A THR 128.A OG1 ALA 129.A O no hydrogen 3.163 N/A THR 128.A OG1 THR 134.A OG1 no hydrogen 3.133 N/A HIS 133.A N PRO 130.A O no hydrogen 3.008 N/A THR 134.A N PRO 130.A O no hydrogen 3.333 N/A THR 134.A OG1 THR 128.A OG1 no hydrogen 3.133 N/A THR 134.A OG1 ALA 129.A O no hydrogen 3.181 N/A LEU 135.A N THR 131.A O no hydrogen 2.873 N/A ARG 136.A N GLY 132.A O no hydrogen 2.900 N/A LEU 137.A N HIS 133.A O no hydrogen 2.850 N/A LEU 138.A N THR 134.A O no hydrogen 2.955 N/A LEU 138.A N LEU 135.A O no hydrogen 3.300 N/A SER 139.A N ARG 136.A O no hydrogen 3.217 N/A SER 139.A OG ARG 136.A O no hydrogen 3.018 N/A ILE 143.A N SER 139.A O no hydrogen 3.149 N/A LEU 144.A N PHE 140.A O no hydrogen 2.896 N/A GLU 145.A N PRO 141.A O no hydrogen 2.954 N/A LYS 146.A N THR 142.A O no hydrogen 2.907 N/A ALA 147.A N ILE 143.A O no hydrogen 2.881 N/A PHE 148.A N LEU 144.A O no hydrogen 2.911 N/A ALA 149.A N GLU 145.A O no hydrogen 2.908 N/A LYS 150.A N LYS 146.A O no hydrogen 2.872 N/A LYS 150.A NZ GLU 153.A OE1 no hydrogen 3.549 N/A LYS 150.A NZ GLU 153.A OE2 no hydrogen 3.408 N/A VAL 151.A N ALA 147.A O no hydrogen 2.935 N/A TRP 152.A N PHE 148.A O no hydrogen 2.930 N/A GLU 153.A N ALA 149.A O no hydrogen 2.847 N/A LEU 154.A N LYS 150.A O no hydrogen 2.920 N/A LYS 155.A N VAL 151.A O no hydrogen 2.891 N/A LYS 155.A NZ GLU 180.A OE2 no hydrogen 2.704 N/A ASP 156.A N TRP 152.A O no hydrogen 2.871 N/A ARG 157.A N GLU 153.A O no hydrogen 2.917 N/A PHE 158.A N LEU 154.A O no hydrogen 2.900 N/A ILE 162.A N PHE 158.A O no hydrogen 2.889 N/A GLY 163.A N GLY 159.A O no hydrogen 2.896 N/A GLN 164.A N GLY 160.A O no hydrogen 2.912 N/A ALA 165.A N LEU 161.A O no hydrogen 2.930 N/A THR 166.A N ILE 162.A O no hydrogen 2.842 N/A THR 166.A OG1 ILE 162.A O no hydrogen 2.823 N/A THR 166.A OG1 ASN 174.A OD1 no hydrogen 2.421 N/A ALA 167.A N GLY 163.A O no hydrogen 2.967 N/A LEU 168.A N ALA 165.A O no hydrogen 2.959 N/A MET 169.A N ALA 165.A O no hydrogen 3.195 N/A ALA 176.A N ASN 174.A OD1 no hydrogen 2.814 N/A ALA 178.A N ASN 174.A O no hydrogen 2.798 N/A GLN 179.A N PRO 175.A O no hydrogen 2.912 N/A GLU 180.A N ALA 176.A O no hydrogen 2.918 N/A GLN 181.A N ALA 177.A O no hydrogen 2.858 N/A LEU 182.A N ALA 178.A O no hydrogen 2.898 N/A LEU 183.A N GLN 179.A O no hydrogen 2.927 N/A GLY 184.A N GLU 180.A O no hydrogen 2.878 N/A LYS 185.A N GLN 181.A O no hydrogen 2.912 N/A LEU 186.A N LEU 182.A O no hydrogen 2.921 N/A GLU 187.A N LEU 183.A O no hydrogen 2.875 N/A GLU 188.A N GLY 184.A O no hydrogen 2.915 N/A THR 189.A N LYS 185.A O no hydrogen 2.972 N/A THR 189.A OG1 LYS 185.A O no hydrogen 3.140 N/A ARG 190.A N LEU 186.A O no hydrogen 2.841 N/A ARG 190.A NH2 GLU 187.A OE1 no hydrogen 2.938 N/A ALA 191.A N GLU 187.A O no hydrogen 2.880 N/A VAL 192.A N GLU 188.A O no hydrogen 3.038 N/A ILE 193.A N THR 189.A O no hydrogen 2.915 N/A ASN 194.A N ARG 190.A O no hydrogen 2.790 N/A LYS 195.A N ALA 191.A O no hydrogen 2.997 N/A VAL 196.A N VAL 192.A O no hydrogen 2.974 N/A ASN 197.A N ILE 193.A O no hydrogen 2.815 N/A GLN 198.A N ASN 194.A O no hydrogen 2.891 N/A ALA 199.A N LYS 195.A O no hydrogen 2.964 N/A PHE 200.A N VAL 196.A O no hydrogen 2.896 N/A PHE 200.A N ASN 197.A O no hydrogen 2.987 N/A GLN 201.A N ASN 197.A O no hydrogen 3.079 N/A THR 204.A N ASP 202.A OD1 no hydrogen 3.135 N/A THR 204.A OG1 ASP 202.A OD1 no hydrogen 3.480 N/A LYS 205.A N ASP 202.A O no hydrogen 2.937 N/A THR 206.A N ASP 202.A O no hydrogen 2.926 N/A THR 206.A OG1 ALA 199.A O no hydrogen 2.785 N/A THR 207.A N TRP 18.A O no hydrogen 3.116 N/A THR 207.A OG1 ASP 235.A OD2 no hydrogen 3.308 N/A VAL 209.A N PHE 20.A O no hydrogen 2.703 N/A CYS 210.A N ASN 238.A O no hydrogen 2.932 N/A CYS 210.A SG SER 236.A OG no hydrogen 3.539 N/A VAL 211.A N GLY 22.A O no hydrogen 2.980 N/A CYS 212.A N VAL 240.A O no hydrogen 2.787 N/A CYS 212.A SG VAL 240.A O no hydrogen 3.983 N/A ILE 213.A N SER 218.A OG no hydrogen 3.069 N/A GLU 215.A N ILE 213.A O no hydrogen 2.494 N/A ILE 219.A N GLU 215.A O no hydrogen 3.279 N/A TYR 220.A N PHE 216.A O no hydrogen 2.876 N/A GLU 221.A N LEU 217.A O no hydrogen 2.934 N/A THR 222.A N SER 218.A O no hydrogen 2.880 N/A THR 222.A OG1 SER 218.A O no hydrogen 2.813 N/A GLU 223.A N ILE 219.A O no hydrogen 2.885 N/A ARG 224.A N TYR 220.A O no hydrogen 2.945 N/A ARG 224.A NH1 GLU 221.A OE1 no hydrogen 3.154 N/A LEU 225.A N GLU 221.A O no hydrogen 2.888 N/A VAL 226.A N THR 222.A O no hydrogen 2.874 N/A GLN 227.A N GLU 223.A O no hydrogen 2.939 N/A GLN 227.A NE2 GLU 223.A OE2 no hydrogen 2.873 N/A GLU 228.A N ARG 224.A O no hydrogen 2.923 N/A LEU 229.A N LEU 225.A O no hydrogen 2.890 N/A SER 230.A N VAL 226.A O no hydrogen 2.907 N/A LYS 231.A N GLN 227.A O no hydrogen 2.902 N/A TYR 232.A N GLU 228.A O no hydrogen 2.960 N/A GLY 233.A N SER 230.A O no hydrogen 3.220 N/A ILE 234.A N LEU 229.A O no hydrogen 2.744 N/A SER 236.A OG PHE 208.A O no hydrogen 2.898 N/A HIS 237.A ND1 ASP 235.A OD2 no hydrogen 2.747 N/A HIS 237.A NE2 ASN 9.A OD1 no hydrogen 2.745 N/A ASN 238.A ND2 ASN 9.A OD1 no hydrogen 3.134 N/A ILE 239.A N HIS 299.A O no hydrogen 2.884 N/A VAL 240.A N CYS 210.A O no hydrogen 2.646 N/A VAL 241.A N VAL 301.A O no hydrogen 2.887 N/A ASN 242.A N CYS 212.A O no hydrogen 2.665 N/A GLN 243.A N ASN 242.A OD1 no hydrogen 3.102 N/A GLN 243.A NE2 GLY 26.A O no hydrogen 3.212 N/A VAL 244.A N MET 303.A O no hydrogen 2.669 N/A LEU 245.A N GLN 283.A OE1 no hydrogen 2.593 N/A LYS 249.A NZ GLU 253.A OE2 no hydrogen 3.150 N/A ALA 251.A N ASP 250.A OD1 no hydrogen 2.910 N/A ALA 256.A N GLU 252.A O no hydrogen 2.829 N/A TRP 257.A N GLU 253.A O no hydrogen 2.962 N/A TYR 258.A N LEU 254.A O no hydrogen 2.898 N/A GLU 259.A N SER 255.A O no hydrogen 2.858 N/A ALA 260.A N ALA 256.A O no hydrogen 2.923 N/A ASN 261.A N TRP 257.A O no hydrogen 2.940 N/A ASN 261.A N TYR 258.A O no hydrogen 3.001 N/A THR 264.A OG1 ASN 261.A O no hydrogen 2.868 N/A LEU 265.A N GLY 262.A O no hydrogen 3.488 N/A GLU 268.A N GLU 268.A OE1 no hydrogen 2.668 N/A ARG 270.A N PRO 266.A O no hydrogen 2.888 N/A GLU 271.A N LYS 267.A O no hydrogen 2.918 N/A ILE 272.A N GLU 268.A O no hydrogen 2.968 N/A CYS 273.A N ALA 269.A O no hydrogen 2.913 N/A CYS 273.A SG ALA 269.A O no hydrogen 3.169 N/A SER 274.A N ARG 270.A O no hydrogen 2.911 N/A LYS 275.A N GLU 271.A O no hydrogen 2.966 N/A LEU 276.A N ILE 272.A O no hydrogen 2.909 N/A LEU 277.A N CYS 273.A O no hydrogen 2.877 N/A ALA 278.A N SER 274.A O no hydrogen 2.971 N/A ARG 279.A N LYS 275.A O no hydrogen 2.958 N/A LYS 280.A N LEU 276.A O no hydrogen 2.871 N/A LYS 280.A NZ LEU 245.A O no hydrogen 2.943 N/A LYS 280.A NZ PHE 246.A O no hydrogen 2.728 N/A LYS 280.A NZ LYS 249.A O no hydrogen 3.448 N/A ARG 281.A N LEU 277.A O no hydrogen 2.914 N/A MET 282.A N ALA 278.A O no hydrogen 3.000 N/A GLN 283.A N ARG 279.A O no hydrogen 2.914 N/A GLN 283.A NE2 GLN 243.A O no hydrogen 3.526 N/A ASP 284.A N LYS 280.A O no hydrogen 2.860 N/A LYS 285.A N ARG 281.A O no hydrogen 2.963 N/A TYR 286.A N MET 282.A O no hydrogen 3.003 N/A ILE 287.A N GLN 283.A O no hydrogen 2.849 N/A GLY 288.A N ASP 284.A O no hydrogen 2.895 N/A GLN 289.A N LYS 285.A O no hydrogen 2.958 N/A CYS 290.A N TYR 286.A O no hydrogen 2.912 N/A CYS 290.A SG TYR 286.A O no hydrogen 3.471 N/A PHE 291.A N ILE 287.A O no hydrogen 2.900 N/A ASP 292.A N GLY 288.A O no hydrogen 2.893 N/A LEU 293.A N GLN 289.A O no hydrogen 2.938 N/A TYR 294.A N CYS 290.A O no hydrogen 2.786 N/A TYR 294.A OH GLU 223.A OE1 no hydrogen 2.832 N/A HIS 299.A N HIS 237.A O no hydrogen 2.912 N/A HIS 299.A ND1 ASP 4.A O no hydrogen 3.101 N/A VAL 301.A N ILE 239.A O no hydrogen 2.898 N/A MET 303.A N VAL 241.A O no hydrogen 2.906 N/A LEU 305.A N VAL 244.A O no hydrogen 2.717 N/A ARG 311.A N GLU 309.A O no hydrogen 2.765 N/A ARG 311.A NE ASP 60.A O no hydrogen 3.025 N/A GLY 312.A N ALA 61.A O no hydrogen 3.055 N/A LEU 316.A N GLY 312.A O no hydrogen 3.144 N/A LYS 317.A N VAL 313.A O no hydrogen 2.880 N/A THR 318.A N GLU 314.A O no hydrogen 2.950 N/A THR 318.A OG1 GLU 314.A O no hydrogen 3.109 N/A PHE 319.A N LYS 315.A O no hydrogen 2.904 N/A SER 320.A N LEU 316.A O no hydrogen 2.853 N/A SER 320.A OG GLN 39.A OE1 no hydrogen 2.971 N/A SER 320.A OG LEU 316.A O no hydrogen 3.201 N/A SER 320.A OG LYS 317.A O no hydrogen 2.644 N/A GLU 321.A N LYS 317.A O no hydrogen 2.931 N/A LEU 322.A N THR 318.A O no hydrogen 2.958 N/A LEU 323.A N SER 320.A O no hydrogen 3.039 N/A VAL 324.A N SER 320.A O no hydrogen 2.935 N/A ASP 325.A N GLU 321.A O no hydrogen 3.224 N/A