Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8he8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 7.A N ASP 5.A OD1 no hydrogen 2.647 N/A ARG 7.A NH1 ASP 5.A OD1 no hydrogen 3.207 N/A VAL 8.A N ASP 5.A O no hydrogen 2.967 N/A GLN 9.A N ASP 5.A O no hydrogen 3.128 N/A GLU 10.A N LEU 6.A O no hydrogen 3.323 N/A LEU 11.A N ARG 7.A O no hydrogen 3.295 N/A ILE 12.A N VAL 8.A O no hydrogen 2.827 N/A LYS 13.A N GLN 9.A O no hydrogen 2.815 N/A LEU 14.A N GLU 10.A O no hydrogen 3.212 N/A ILE 15.A N LEU 11.A O no hydrogen 3.133 N/A CYS 16.A N ILE 12.A O no hydrogen 2.977 N/A CYS 16.A SG ILE 12.A O no hydrogen 3.258 N/A GLN 19.A N ASN 17.A OD1 no hydrogen 3.096 N/A GLU 22.A N VAL 18.A O no hydrogen 2.731 N/A GLU 23.A N GLN 19.A O no hydrogen 3.189 N/A GLU 23.A N ALA 20.A O no hydrogen 3.264 N/A MET 24.A N ALA 20.A O no hydrogen 2.991 N/A MET 25.A N MET 21.A O no hydrogen 3.250 N/A GLU 27.A N GLU 23.A O no hydrogen 3.055 N/A MET 28.A N MET 24.A O no hydrogen 3.214 N/A LYS 29.A N MET 26.A O no hydrogen 2.816 N/A TYR 30.A N MET 25.A O no hydrogen 2.822 N/A TYR 30.A OH ALA 35.A O no hydrogen 3.136 N/A ASN 31.A N PRO 80.A O no hydrogen 2.860 N/A LYS 34.A N ASN 31.A OD1 no hydrogen 2.603 N/A ALA 35.A N ASN 31.A O no hydrogen 3.378 N/A LYS 39.A N PRO 36.A O no hydrogen 2.947 N/A GLN 44.A NE2 ARG 78.A O no hydrogen 3.220 N/A ILE 45.A N THR 41.A O no hydrogen 3.085 N/A LYS 46.A N VAL 42.A O no hydrogen 2.757 N/A LYS 46.A NZ GLU 219.A OE2 no hydrogen 3.484 N/A ALA 47.A N ALA 43.A O no hydrogen 2.847 N/A GLY 48.A N GLN 44.A O no hydrogen 2.949 N/A TYR 49.A N ILE 45.A O no hydrogen 3.031 N/A GLN 50.A N LYS 46.A O no hydrogen 2.937 N/A SER 51.A N ALA 47.A O no hydrogen 3.109 N/A SER 51.A OG ALA 47.A O no hydrogen 3.347 N/A LEU 52.A N GLY 48.A O no hydrogen 2.944 N/A LYS 53.A N TYR 49.A O no hydrogen 3.015 N/A LYS 53.A NZ ASP 57.A OD1 no hydrogen 3.543 N/A LYS 54.A N GLN 50.A O no hydrogen 2.889 N/A LYS 54.A NZ ASP 57.A OD2 no hydrogen 2.632 N/A ILE 55.A N SER 51.A O no hydrogen 2.913 N/A GLU 56.A N LEU 52.A O no hydrogen 2.872 N/A ASP 57.A N LYS 53.A O no hydrogen 2.715 N/A CYS 58.A N LYS 54.A O no hydrogen 3.134 N/A CYS 58.A SG LYS 54.A O no hydrogen 3.445 N/A ILE 59.A N ILE 55.A O no hydrogen 3.118 N/A ARG 60.A N GLU 56.A O no hydrogen 2.887 N/A ARG 60.A NH2 ASP 57.A OD1 no hydrogen 2.830 N/A ALA 61.A N ASP 57.A O no hydrogen 3.191 N/A GLY 62.A N ILE 59.A O no hydrogen 3.032 N/A HIS 64.A N GLY 62.A O no hydrogen 2.708 N/A LEU 68.A N HIS 64.A O no hydrogen 3.493 N/A MET 69.A N GLY 65.A O no hydrogen 3.486 N/A GLU 70.A N ARG 66.A O no hydrogen 2.546 N/A ALA 71.A N ALA 67.A O no hydrogen 3.230 N/A CYS 72.A N LEU 68.A O no hydrogen 2.858 N/A CYS 72.A SG LEU 68.A O no hydrogen 3.155 N/A ASN 73.A N MET 69.A O no hydrogen 2.826 N/A GLU 74.A N GLU 70.A O no hydrogen 3.106 N/A PHE 75.A N ALA 71.A O no hydrogen 2.838 N/A TYR 76.A N CYS 72.A O no hydrogen 2.733 N/A TYR 76.A OH PRO 89.A O no hydrogen 2.640 N/A THR 77.A N ASN 73.A O no hydrogen 3.091 N/A THR 77.A N GLU 74.A O no hydrogen 3.113 N/A THR 77.A OG1 ASN 73.A O no hydrogen 2.345 N/A ARG 78.A N GLU 74.A O no hydrogen 3.033 N/A ILE 79.A N PHE 75.A O no hydrogen 2.749 N/A ASP 82.A N LYS 29.A O no hydrogen 2.790 N/A ARG 92.A N GLU 96.A OE2 no hydrogen 3.435 N/A THR 93.A OG1 GLU 96.A OE2 no hydrogen 3.101 N/A LEU 97.A N THR 93.A O no hydrogen 3.322 N/A SER 98.A N GLN 94.A O no hydrogen 2.767 N/A GLU 99.A N LYS 95.A O no hydrogen 2.949 N/A LYS 100.A N GLU 96.A O no hydrogen 2.974 N/A LYS 100.A NZ HIS 81.A NE2 no hydrogen 3.355 N/A ILE 101.A N LEU 97.A O no hydrogen 2.779 N/A LEU 103.A N GLU 99.A O no hydrogen 3.205 N/A LEU 104.A N LYS 100.A O no hydrogen 2.970 N/A GLU 105.A N ILE 101.A O no hydrogen 2.603 N/A ALA 106.A N GLN 102.A O no hydrogen 2.635 N/A LEU 107.A N LEU 103.A O no hydrogen 2.639 N/A GLY 108.A N LEU 104.A O no hydrogen 2.757 N/A GLY 108.A N GLU 105.A O no hydrogen 3.070 N/A ASP 109.A N GLU 105.A O no hydrogen 3.149 N/A ILE 110.A N ALA 106.A O no hydrogen 2.940 N/A ILE 112.A N GLY 108.A O no hydrogen 3.310 N/A ALA 113.A N ASP 109.A O no hydrogen 2.982 N/A ILE 114.A N ILE 110.A O no hydrogen 2.903 N/A LYS 115.A N GLU 111.A O no hydrogen 2.890 N/A LEU 116.A N ILE 112.A O no hydrogen 2.941 N/A VAL 117.A N ALA 113.A O no hydrogen 2.825 N/A LYS 118.A N ILE 114.A O no hydrogen 2.913 N/A SER 119.A N LEU 116.A O no hydrogen 3.084 N/A LEU 124.A N GLN 122.A OE1 no hydrogen 2.609 N/A LEU 128.A N HIS 126.A ND1 no hydrogen 3.060 N/A ASP 129.A N HIS 126.A O no hydrogen 2.651 N/A GLN 130.A N HIS 126.A O no hydrogen 3.214 N/A GLN 130.A N PRO 127.A O no hydrogen 3.217 N/A GLN 130.A NE2 GLN 122.A O no hydrogen 2.704 N/A GLN 130.A NE2 GLU 125.A O no hydrogen 3.149 N/A HIS 131.A N PRO 127.A O no hydrogen 3.254 N/A ARG 133.A N ASP 129.A O no hydrogen 3.075 N/A ARG 133.A NE GLU 125.A OE2 no hydrogen 3.181 N/A ASN 134.A N GLN 130.A O no hydrogen 2.783 N/A LEU 135.A N HIS 131.A O no hydrogen 2.867 N/A HIS 136.A N ARG 133.A O no hydrogen 2.989 N/A CYS 137.A SG ALA 138.A O no hydrogen 3.897 N/A CYS 137.A SG LEU 209.A O no hydrogen 3.736 N/A ALA 138.A N GLU 178.A O no hydrogen 2.731 N/A LEU 139.A N TYR 132.A OH no hydrogen 2.838 N/A ARG 140.A N GLU 176.A O no hydrogen 3.061 N/A LEU 142.A N LEU 174.A O no hydrogen 2.867 N/A HIS 144.A ND1 ASP 143.A OD1 no hydrogen 2.766 N/A GLU 145.A N ASP 143.A OD1 no hydrogen 2.871 N/A SER 146.A N ASP 143.A O no hydrogen 2.950 N/A SER 146.A OG ASP 143.A O no hydrogen 3.080 N/A GLU 148.A N GLU 148.A OE1 no hydrogen 2.485 N/A PHE 149.A N SER 146.A OG no hydrogen 2.986 N/A LYS 150.A N SER 146.A O no hydrogen 3.095 N/A LYS 150.A NZ GLU 145.A O no hydrogen 2.981 N/A LYS 150.A NZ GLU 145.A OE1 no hydrogen 3.097 N/A VAL 151.A N TYR 147.A O no hydrogen 3.340 N/A ILE 152.A N GLU 148.A O no hydrogen 2.966 N/A SER 153.A N PHE 149.A O no hydrogen 3.002 N/A SER 153.A OG PHE 149.A O no hydrogen 2.670 N/A GLN 154.A N LYS 150.A O no hydrogen 3.148 N/A TYR 155.A N VAL 151.A O no hydrogen 2.832 N/A TYR 155.A OH LEU 195.A O no hydrogen 2.895 N/A LEU 156.A N ILE 152.A O no hydrogen 2.942 N/A GLN 157.A N SER 153.A O no hydrogen 3.065 N/A GLN 157.A NE2 MET 169.A O no hydrogen 3.032 N/A SER 158.A N GLN 154.A O no hydrogen 2.731 N/A SER 158.A OG GLN 154.A O no hydrogen 2.470 N/A THR 159.A N TYR 155.A O no hydrogen 3.335 N/A THR 159.A OG1 TYR 155.A O no hydrogen 2.865 N/A THR 159.A OG1 SER 237.A OG no hydrogen 3.199 N/A HIS 160.A NE2 HIS 164.A O no hydrogen 3.002 N/A ALA 161.A N SER 238.A OG no hydrogen 2.528 N/A THR 163.A N TYR 326.A OH no hydrogen 3.319 N/A THR 163.A OG1 TYR 326.A OH no hydrogen 2.800 N/A HIS 164.A N ALA 161.A O no hydrogen 3.224 N/A HIS 164.A ND1 SER 238.A OG no hydrogen 3.047 N/A ASP 166.A N ASP 166.A OD1 no hydrogen 2.612 N/A TYR 167.A OH ASN 242.A OD1 no hydrogen 2.451 N/A THR 168.A N ASN 348.A O no hydrogen 2.827 N/A THR 168.A OG1 ASN 348.A OD1 no hydrogen 2.921 N/A THR 170.A N GLN 346.A O no hydrogen 3.050 N/A THR 170.A OG1 ASN 348.A OD1 no hydrogen 2.753 N/A LEU 172.A N LYS 344.A O no hydrogen 2.796 N/A PHE 175.A N LEU 342.A O no hydrogen 2.774 N/A GLU 176.A N ARG 140.A O no hydrogen 2.675 N/A VAL 177.A N ARG 340.A O no hydrogen 2.887 N/A GLU 178.A N ALA 138.A O no hydrogen 3.160 N/A ASP 180.A N HIS 136.A O no hydrogen 3.370 N/A GLU 182.A N LYS 179.A O no hydrogen 3.075 N/A GLU 184.A N GLU 184.A OE1 no hydrogen 2.427 N/A PHE 186.A N LYS 183.A O no hydrogen 3.235 N/A ARG 187.A N ASN 335.A O no hydrogen 2.975 N/A LEU 190.A N ARG 187.A O no hydrogen 2.903 N/A ASN 192.A ND2 GLY 263.A O no hydrogen 3.511 N/A MET 194.A N VAL 260.A O no hydrogen 2.934 N/A LEU 195.A N THR 305.A O no hydrogen 3.013 N/A LEU 196.A N SER 258.A O no hydrogen 3.154 N/A TRP 197.A N ALA 234.A O no hydrogen 2.579 N/A HIS 198.A N LEU 256.A O no hydrogen 2.848 N/A HIS 198.A ND1 TYR 232.A O no hydrogen 2.758 N/A ARG 201.A NH1 GLN 102.A OE1 no hydrogen 3.104 N/A ARG 201.A NH2 GLN 102.A OE1 no hydrogen 3.496 N/A ASN 204.A N ARG 201.A O no hydrogen 3.317 N/A ASN 204.A ND2 SER 200.A OG no hydrogen 3.014 N/A TRP 205.A N MET 202.A O no hydrogen 3.080 N/A ILE 208.A N ASN 204.A O no hydrogen 2.916 N/A LEU 209.A N TRP 205.A O no hydrogen 3.296 N/A SER 210.A N VAL 206.A O no hydrogen 3.152 N/A SER 210.A OG VAL 206.A O no hydrogen 2.596 N/A SER 210.A OG HIS 211.A ND1 no hydrogen 2.758 N/A HIS 211.A N GLY 207.A O no hydrogen 2.847 N/A HIS 211.A ND1 SER 210.A OG no hydrogen 2.758 N/A ARG 214.A NH1 GLY 207.A O no hydrogen 3.160 N/A ARG 214.A NH2 ASP 109.A OD2 no hydrogen 3.355 N/A ALA 220.A N PRO 217.A O no hydrogen 3.245 N/A THR 223.A N GLU 56.A OE2 no hydrogen 3.377 N/A THR 223.A OG1 GLU 56.A OE2 no hydrogen 2.786 N/A GLY 224.A N PRO 221.A O no hydrogen 3.317 N/A TYR 225.A N ILE 222.A O no hydrogen 3.393 N/A PHE 227.A N TYR 232.A OH no hydrogen 2.720 N/A GLY 228.A N TYR 225.A O no hydrogen 3.211 N/A LYS 229.A NZ PRO 217.A O no hydrogen 2.600 N/A LYS 229.A NZ ALA 220.A O no hydrogen 2.798 N/A GLY 230.A N GLY 228.A O no hydrogen 3.008 N/A ILE 231.A N VAL 331.A O no hydrogen 2.743 N/A TYR 232.A OH GLY 228.A O no hydrogen 2.765 N/A PHE 233.A N TYR 329.A O no hydrogen 2.625 N/A ALA 234.A N TRP 197.A O no hydrogen 2.952 N/A SER 237.A N THR 159.A O no hydrogen 2.956 N/A SER 237.A N THR 159.A OG1 no hydrogen 2.905 N/A SER 237.A OG LEU 156.A O no hydrogen 2.673 N/A SER 237.A OG THR 159.A OG1 no hydrogen 3.199 N/A SER 238.A OG HIS 164.A ND1 no hydrogen 3.047 N/A LYS 239.A NZ TYR 326.A O no hydrogen 2.845 N/A LYS 239.A NZ ASN 327.A O no hydrogen 3.107 N/A LYS 239.A NZ GLU 328.A OE1 no hydrogen 3.068 N/A SER 240.A N MET 236.A O no hydrogen 3.445 N/A ALA 241.A N SER 237.A O no hydrogen 2.886 N/A ASN 242.A N SER 238.A O no hydrogen 2.805 N/A TYR 243.A N SER 240.A O no hydrogen 3.068 N/A CYS 244.A N ALA 241.A O no hydrogen 3.033 N/A CYS 244.A SG SER 200.A O no hydrogen 3.681 N/A CYS 244.A SG SER 240.A O no hydrogen 3.995 N/A CYS 244.A SG LEU 254.A O no hydrogen 3.195 N/A PHE 245.A N ASN 242.A O no hydrogen 2.971 N/A SER 247.A N LYS 250.A O no hydrogen 2.904 N/A ASN 251.A N ASN 251.A OD1 no hydrogen 2.632 N/A ASN 251.A ND2 PHE 347.A O no hydrogen 3.399 N/A GLY 253.A N VAL 345.A O no hydrogen 2.717 N/A LEU 255.A N LEU 343.A O no hydrogen 2.996 N/A LEU 256.A N HIS 198.A O no hydrogen 2.865 N/A LEU 257.A N TYR 341.A O no hydrogen 3.183 N/A SER 258.A N LEU 196.A O no hydrogen 3.220 N/A GLU 259.A N ARG 338.A O no hydrogen 2.776 N/A VAL 260.A N MET 194.A O no hydrogen 2.877 N/A ALA 261.A N GLN 336.A O no hydrogen 3.001 N/A LEU 262.A N ASN 192.A O no hydrogen 3.097 N/A GLY 263.A N HIS 191.A O no hydrogen 2.767 N/A GLN 264.A N HIS 283.A ND1 no hydrogen 2.952 N/A GLN 264.A NE2 HIS 191.A NE2 no hydrogen 3.538 N/A CYS 265.A SG GLY 263.A O no hydrogen 3.855 N/A CYS 265.A SG SER 284.A OG no hydrogen 3.204 N/A ASN 266.A N SER 284.A O no hydrogen 2.529 N/A LEU 268.A N LYS 286.A O no hydrogen 2.934 N/A ASN 272.A N MET 226.A O no hydrogen 2.916 N/A LYS 274.A N ASN 272.A OD1 no hydrogen 3.168 N/A GLY 277.A N LYS 274.A O no hydrogen 3.192 N/A LEU 278.A N ALA 275.A O no hydrogen 3.213 N/A LEU 279.A N GLU 276.A O no hydrogen 3.301 N/A LYS 282.A N LEU 279.A O no hydrogen 3.413 N/A LYS 282.A NZ ASN 266.A OD1 no hydrogen 3.500 N/A HIS 283.A N GLN 264.A O no hydrogen 2.925 N/A SER 284.A OG LEU 262.A O no hydrogen 3.436 N/A THR 285.A N ILE 330.A O no hydrogen 3.114 N/A THR 285.A OG1 TYR 332.A OH no hydrogen 2.578 N/A LYS 286.A N ASN 266.A O no hydrogen 3.323 N/A LYS 286.A NZ TYR 329.A OH no hydrogen 2.821 N/A GLY 287.A N GLU 328.A O no hydrogen 2.527 N/A LEU 288.A N LEU 268.A O no hydrogen 2.915 N/A GLY 289.A N ASN 327.A OD1 no hydrogen 2.580 N/A LYS 290.A N LEU 324.A O no hydrogen 2.852 N/A ALA 292.A N SER 312.A O no hydrogen 2.882 N/A ALA 296.A N SER 294.A OG no hydrogen 3.328 N/A HIS 297.A N SER 294.A O no hydrogen 3.142 N/A VAL 299.A N VAL 306.A O no hydrogen 3.217 N/A LEU 301.A N SER 304.A O no hydrogen 3.076 N/A ASN 302.A ND2 GLU 148.A OE2 no hydrogen 3.145 N/A ASN 302.A ND2 TYR 341.A OH no hydrogen 2.787 N/A SER 304.A OG GLU 259.A OE2 no hydrogen 2.641 N/A THR 305.A N ARG 193.A O no hydrogen 2.944 N/A VAL 306.A N VAL 299.A O no hydrogen 2.633 N/A LEU 308.A N VAL 306.A O no hydrogen 2.649 N/A SER 312.A N ALA 292.A O no hydrogen 2.982 N/A THR 314.A N LYS 290.A O no hydrogen 3.292 N/A THR 314.A OG1 GLY 289.A O no hydrogen 2.425 N/A GLY 315.A N ASP 313.A OD1 no hydrogen 2.611 N/A ILE 316.A N THR 314.A OG1 no hydrogen 3.314 N/A TYR 322.A N ASP 320.A OD1 no hydrogen 2.474 N/A THR 323.A N ASP 320.A O no hydrogen 3.087 N/A THR 323.A OG1 LEU 317.A O no hydrogen 3.217 N/A THR 323.A OG1 ASP 320.A O no hydrogen 2.717 N/A TYR 326.A OH THR 163.A OG1 no hydrogen 2.800 N/A GLU 328.A N GLY 287.A O no hydrogen 2.951 N/A TYR 329.A N PHE 233.A O no hydrogen 2.869 N/A ILE 330.A N THR 285.A O no hydrogen 2.961 N/A VAL 331.A N ILE 231.A O no hydrogen 3.229 N/A TYR 332.A OH PHE 227.A O no hydrogen 2.568 N/A TYR 332.A OH THR 285.A OG1 no hydrogen 2.578 N/A ASN 335.A N ASN 333.A OD1 no hydrogen 3.096 N/A GLN 336.A N ASN 333.A O no hydrogen 2.925 N/A GLN 336.A NE2 ALA 261.A O no hydrogen 2.892 N/A GLN 336.A NE2 HIS 283.A O no hydrogen 2.770 N/A VAL 337.A N PRO 334.A O no hydrogen 3.130 N/A ARG 338.A N GLU 259.A O no hydrogen 2.794 N/A ARG 338.A NH1 GLU 259.A OE1 no hydrogen 2.900 N/A MET 339.A N GLU 182.A OE1 no hydrogen 2.529 N/A ARG 340.A N LEU 257.A O no hydrogen 3.285 N/A ARG 340.A NH2 GLU 176.A OE2 no hydrogen 3.156 N/A TYR 341.A N LEU 257.A O no hydrogen 2.946 N/A LEU 342.A N PHE 175.A O no hydrogen 2.725 N/A LEU 343.A N LEU 255.A O no hydrogen 2.833 N/A LYS 344.A N ASP 173.A O no hydrogen 2.837 N/A LYS 344.A NZ ASP 173.A OD2 no hydrogen 3.137 N/A VAL 345.A N GLY 253.A O no hydrogen 2.702 N/A GLN 346.A N THR 170.A O no hydrogen 3.008 N/A PHE 347.A N ASN 251.A O no hydrogen 2.774 N/A ASN 348.A N THR 168.A O no hydrogen 2.739 N/A ASN 348.A ND2 GLN 346.A OE1 no hydrogen 2.970 N/A LEU 350.A N ASP 166.A O no hydrogen 2.540 N/A