Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8hht_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLY 2.A N SER 1.A OG no hydrogen 2.878 N/A ARG 4.A N GLN 297.A OE1 no hydrogen 2.823 N/A PHE 8.A N SER 111.A OG no hydrogen 2.833 N/A SER 10.A OG GLU 14.A OE1 no hydrogen 2.641 N/A VAL 13.A N SER 10.A O no hydrogen 2.923 N/A GLU 14.A N SER 10.A O no hydrogen 3.071 N/A GLY 15.A N GLY 11.A O no hydrogen 3.296 N/A CYS 16.A N VAL 13.A O no hydrogen 2.715 N/A CYS 16.A SG LYS 12.A O no hydrogen 3.463 N/A CYS 16.A SG TRP 31.A O no hydrogen 3.619 N/A MET 17.A N GLU 14.A O no hydrogen 3.150 N/A VAL 18.A N GLY 29.A O no hydrogen 2.980 N/A GLN 19.A N GLN 67.A O no hydrogen 2.772 N/A VAL 20.A N LEU 27.A O no hydrogen 3.008 N/A THR 21.A N LEU 65.A O no hydrogen 2.780 N/A THR 21.A OG1 THR 26.A OG1 no hydrogen 2.507 N/A CYS 22.A N THR 25.A O no hydrogen 2.862 N/A CYS 22.A SG ASN 63.A O no hydrogen 3.916 N/A THR 25.A N CYS 22.A O no hydrogen 3.025 N/A THR 25.A OG1 CYS 44.A O no hydrogen 2.824 N/A THR 26.A OG1 THR 21.A OG1 no hydrogen 2.507 N/A LEU 27.A N VAL 20.A O no hydrogen 3.017 N/A ASN 28.A N CYS 143.A O no hydrogen 3.095 N/A ASN 28.A ND2 CYS 115.A O no hydrogen 3.125 N/A ASN 28.A ND2 GLY 141.A O no hydrogen 2.830 N/A ASN 28.A ND2 CYS 143.A O no hydrogen 2.948 N/A GLY 29.A N VAL 18.A O no hydrogen 2.900 N/A LEU 30.A N TYR 37.A O no hydrogen 2.726 N/A TRP 31.A N CYS 16.A O no hydrogen 2.755 N/A LEU 32.A N VAL 35.A O no hydrogen 2.925 N/A ASP 33.A N THR 96.A OG1 no hydrogen 3.082 N/A VAL 35.A N LEU 32.A O no hydrogen 3.109 N/A VAL 36.A N LEU 87.A O no hydrogen 2.777 N/A TYR 37.A N LEU 30.A O no hydrogen 2.676 N/A CYS 38.A N LEU 85.A O no hydrogen 3.136 N/A CYS 38.A SG PRO 39.A O no hydrogen 3.467 N/A ARG 40.A N CYS 83.A O no hydrogen 3.040 N/A ARG 40.A NE ASP 185.A OD2 no hydrogen 2.625 N/A ARG 40.A NH2 ASP 185.A OD1 no hydrogen 2.809 N/A ARG 40.A NH2 ASP 185.A OD2 no hydrogen 3.498 N/A VAL 42.A N PRO 39.A O no hydrogen 3.291 N/A ILE 43.A N ARG 40.A O no hydrogen 3.207 N/A CYS 44.A N HIS 41.A O no hydrogen 3.295 N/A CYS 44.A SG ASP 46.A O no hydrogen 3.894 N/A MET 47.A N ASP 46.A OD2 no hydrogen 2.848 N/A TYR 52.A OH ASP 185.A O no hydrogen 2.695 N/A ASP 54.A N ASN 51.A OD1 no hydrogen 3.301 N/A LEU 55.A N ASN 51.A O no hydrogen 2.951 N/A LEU 56.A N TYR 52.A O no hydrogen 2.881 N/A ILE 57.A N ASP 54.A O no hydrogen 3.230 N/A ARG 58.A N LEU 55.A O no hydrogen 3.247 N/A LYS 59.A N LEU 56.A O no hydrogen 3.229 N/A LYS 59.A NZ LEU 55.A O no hydrogen 3.427 N/A SER 60.A N ASN 63.A OD1 no hydrogen 2.830 N/A ASN 63.A N SER 60.A O no hydrogen 2.794 N/A PHE 64.A N ASN 61.A O no hydrogen 3.138 N/A LEU 65.A N THR 21.A O no hydrogen 2.908 N/A GLN 67.A N GLN 19.A O no hydrogen 2.815 N/A GLN 67.A NE2 GLY 69.A O no hydrogen 3.013 N/A ALA 68.A N VAL 71.A O no hydrogen 2.786 N/A VAL 71.A N ALA 68.A O no hydrogen 2.937 N/A LEU 73.A N VAL 66.A O no hydrogen 2.857 N/A ILE 76.A N LYS 88.A O no hydrogen 2.706 N/A HIS 78.A ND1 ASN 61.A OD1 no hydrogen 2.818 N/A SER 79.A N LYS 86.A O no hydrogen 3.135 N/A GLN 81.A N VAL 84.A O no hydrogen 2.964 N/A ASN 82.A ND2 GLU 176.A O no hydrogen 2.772 N/A CYS 83.A N GLY 177.A O no hydrogen 2.879 N/A CYS 83.A SG ASP 185.A OD2 no hydrogen 3.659 N/A VAL 84.A N GLN 81.A O no hydrogen 2.912 N/A LEU 85.A N CYS 38.A O no hydrogen 2.979 N/A LYS 86.A N SER 79.A O no hydrogen 3.015 N/A LYS 86.A NZ GLN 81.A OE1 no hydrogen 3.467 N/A LEU 87.A N VAL 36.A O no hydrogen 2.778 N/A LYS 88.A N GLY 77.A O no hydrogen 2.790 N/A VAL 89.A N ASP 34.A O no hydrogen 2.842 N/A ASP 90.A N ARG 74.A O no hydrogen 2.913 N/A THR 91.A OG1 ALA 92.A O no hydrogen 3.190 N/A ASN 93.A N ASP 33.A O no hydrogen 2.876 N/A ASN 93.A ND2 GLY 15.A O no hydrogen 3.127 N/A ASN 93.A ND2 TRP 31.A O no hydrogen 2.968 N/A LYS 95.A N ASN 93.A OD1 no hydrogen 3.040 N/A LYS 95.A NZ ASN 93.A OD1 no hydrogen 3.142 N/A THR 96.A N ASN 93.A O no hydrogen 3.054 N/A THR 96.A OG1 ASN 93.A O no hydrogen 2.696 N/A TYR 99.A OH ASP 33.A OD2 no hydrogen 2.994 N/A LYS 100.A N VAL 155.A O no hydrogen 2.782 N/A VAL 102.A N PHE 157.A O no hydrogen 2.832 N/A ARG 103.A NH1 ASP 174.A OD2 no hydrogen 2.931 N/A ARG 103.A NH1 ASN 178.A O no hydrogen 2.983 N/A ARG 103.A NH1 PHE 179.A O no hydrogen 3.396 N/A ARG 103.A NH2 PHE 179.A O no hydrogen 2.772 N/A ILE 104.A N TYR 180.A OH no hydrogen 3.115 N/A GLN 105.A N GLN 108.A OE1 no hydrogen 2.877 N/A GLY 107.A N MET 128.A O no hydrogen 2.827 N/A GLN 108.A N GLN 105.A O no hydrogen 3.040 N/A THR 109.A OG1 ASP 293.A OD1 no hydrogen 3.470 N/A THR 109.A OG1 ASP 293.A OD2 no hydrogen 2.651 N/A PHE 110.A N CYS 126.A O no hydrogen 2.845 N/A SER 111.A N PHE 148.A O no hydrogen 2.938 N/A SER 111.A OG GLN 125.A OE1 no hydrogen 2.708 N/A VAL 112.A N TYR 124.A O no hydrogen 2.826 N/A LEU 113.A N VAL 146.A O no hydrogen 3.223 N/A ALA 114.A N GLY 122.A O no hydrogen 2.898 N/A CYS 115.A N SER 145.A OG no hydrogen 2.835 N/A CYS 115.A SG LEU 113.A O no hydrogen 3.583 N/A TYR 116.A N SER 119.A O no hydrogen 3.000 N/A GLY 118.A N ASN 28.A OD1 no hydrogen 2.800 N/A SER 119.A N TYR 116.A O no hydrogen 2.923 N/A SER 121.A N ALA 114.A O no hydrogen 2.733 N/A SER 121.A OG ALA 114.A O no hydrogen 2.840 N/A TYR 124.A N VAL 112.A O no hydrogen 3.129 N/A TYR 124.A OH SER 137.A O no hydrogen 2.648 N/A CYS 126.A N PHE 110.A O no hydrogen 2.764 N/A CYS 126.A SG LYS 135.A O no hydrogen 3.757 N/A MET 128.A N GLN 108.A O no hydrogen 3.104 N/A ARG 129.A N THR 133.A O no hydrogen 2.879 N/A ARG 129.A NE ASP 195.A OD1 no hydrogen 3.451 N/A ARG 129.A NE ASP 195.A OD2 no hydrogen 2.878 N/A ARG 129.A NH1 ASP 287.A OD1 no hydrogen 3.030 N/A ARG 129.A NH1 ASP 287.A OD2 no hydrogen 3.179 N/A ARG 129.A NH1 GLU 288.A OE2 no hydrogen 2.943 N/A ARG 129.A NH2 THR 196.A O no hydrogen 3.058 N/A ARG 129.A NH2 ASP 287.A OD2 no hydrogen 2.614 N/A ASN 131.A ND2 GLY 193.A O no hydrogen 3.387 N/A PHE 132.A N ARG 129.A O no hydrogen 2.839 N/A THR 133.A N ASN 131.A OD1 no hydrogen 3.265 N/A THR 133.A OG1 ASN 131.A OD1 no hydrogen 2.891 N/A ILE 134.A N HIS 170.A O no hydrogen 2.874 N/A GLY 136.A N HIS 170.A ND1 no hydrogen 3.122 N/A SER 137.A N TYR 124.A OH no hydrogen 3.038 N/A LEU 139.A N TYR 116.A OH no hydrogen 3.107 N/A SER 142.A N LEU 139.A O no hydrogen 2.904 N/A SER 142.A OG LEU 139.A O no hydrogen 2.667 N/A CYS 143.A SG HIS 41.A NE2 no hydrogen 3.638 N/A GLY 144.A N HIS 161.A O no hydrogen 2.853 N/A SER 145.A N SER 142.A O no hydrogen 2.994 N/A SER 145.A OG SER 142.A O no hydrogen 2.770 N/A GLY 147.A N TYR 159.A O no hydrogen 2.859 N/A PHE 148.A N SER 111.A O no hydrogen 2.803 N/A ASN 149.A N SER 156.A O no hydrogen 3.035 N/A ASN 149.A ND2 THR 109.A O no hydrogen 3.284 N/A ASP 151.A N CYS 154.A O no hydrogen 3.053 N/A CYS 154.A N ASP 151.A O no hydrogen 2.843 N/A VAL 155.A N LYS 98.A O no hydrogen 2.784 N/A SER 156.A N ASN 149.A O no hydrogen 2.772 N/A PHE 157.A N LYS 100.A O no hydrogen 2.888 N/A CYS 158.A N GLY 147.A O no hydrogen 3.003 N/A TYR 159.A OH HIS 161.A ND1 no hydrogen 2.947 N/A MET 160.A N THR 173.A O no hydrogen 2.724 N/A HIS 161.A N SER 145.A O no hydrogen 2.705 N/A HIS 161.A ND1 TYR 159.A OH no hydrogen 2.947 N/A HIS 162.A N ALA 171.A O no hydrogen 3.224 N/A HIS 162.A NE2 THR 173.A OG1 no hydrogen 3.097 N/A MET 163.A N ALA 171.A O no hydrogen 3.016 N/A LEU 165.A N VAL 169.A O no hydrogen 2.826 N/A GLY 168.A N LEU 165.A O no hydrogen 2.780 N/A HIS 170.A N ILE 134.A O no hydrogen 2.928 N/A HIS 170.A NE2 GLU 164.A OE2 no hydrogen 3.019 N/A ALA 171.A N MET 163.A O no hydrogen 3.096 N/A THR 173.A N MET 160.A O no hydrogen 2.984 N/A THR 173.A OG1 HIS 162.A NE2 no hydrogen 3.097 N/A THR 173.A OG1 ASP 174.A O no hydrogen 2.657 N/A ASP 174.A N ASN 178.A O no hydrogen 2.977 N/A GLU 176.A N ASP 174.A OD1 no hydrogen 2.997 N/A GLY 177.A N ASP 174.A O no hydrogen 2.932 N/A ASN 178.A N ASP 174.A OD1 no hydrogen 2.932 N/A TYR 180.A N GLY 172.A O no hydrogen 2.855 N/A TYR 180.A OH CYS 158.A O no hydrogen 2.491 N/A VAL 184.A N GLN 190.A OE1 no hydrogen 3.058 N/A GLN 187.A N MET 47.A O no hydrogen 3.129 N/A GLN 190.A N THR 188.A O no hydrogen 2.964 N/A GLN 190.A NE2 VAL 184.A O no hydrogen 2.919 N/A THR 196.A OG1 GLU 238.A OE2.A no hydrogen 2.832 N/A THR 197.A N ASN 236.A O no hydrogen 3.047 N/A ILE 198.A N ASP 287.A OD2 no hydrogen 3.049 N/A THR 199.A OG1 GLU 238.A O no hydrogen 2.576 N/A ASN 201.A ND2 GLY 107.A O no hydrogen 3.049 N/A ASN 201.A ND2 ASP 287.A O no hydrogen 2.802 N/A VAL 202.A N ILE 198.A O no hydrogen 3.137 N/A LEU 203.A N THR 199.A O no hydrogen 3.079 N/A ALA 204.A N VAL 200.A O no hydrogen 3.119 N/A TRP 205.A N ASN 201.A O no hydrogen 3.034 N/A LEU 206.A N VAL 202.A O no hydrogen 2.845 N/A TYR 207.A N LEU 203.A O no hydrogen 2.920 N/A TYR 207.A OH ILE 257.A O no hydrogen 2.748 N/A ALA 208.A N ALA 204.A O no hydrogen 2.845 N/A ALA 209.A N TRP 205.A O no hydrogen 2.873 N/A VAL 210.A N LEU 206.A O no hydrogen 3.190 N/A ILE 211.A N TYR 207.A O no hydrogen 3.082 N/A ASN 212.A N ALA 209.A O no hydrogen 3.177 N/A ASN 212.A ND2 ALA 208.A O no hydrogen 2.547 N/A GLY 213.A N VAL 210.A O no hydrogen 3.382 N/A ASP 214.A N ALA 209.A O no hydrogen 2.874 N/A TRP 216.A NE1 THR 278.A O no hydrogen 3.066 N/A LEU 218.A N ARG 215.A O no hydrogen 3.101 N/A ASN 219.A ND2 ALA 264.A O no hydrogen 2.882 N/A PHE 221.A N ASN 219.A OD1 no hydrogen 2.859 N/A THR 222.A OG1 ASP 261.A OD1 no hydrogen 2.803 N/A THR 223.A OG1 THR 224.A O no hydrogen 3.386 N/A THR 223.A OG1 ASP 227.A OD2.B no hydrogen 2.610 N/A THR 224.A N THR 223.A OG1 no hydrogen 2.670 N/A ASP 227.A N THR 224.A OG1 no hydrogen 2.895 N/A PHE 228.A N THR 224.A O no hydrogen 2.879 N/A ASN 229.A N LEU 225.A O no hydrogen 2.996 N/A ASN 229.A ND2 LEU 240.A O no hydrogen 3.239 N/A LEU 230.A N ASN 226.A O no hydrogen 3.164 N/A VAL 231.A N ASP 227.A O no hydrogen 3.348 N/A ALA 232.A N PHE 228.A O no hydrogen 2.802 N/A MET 233.A N ASN 229.A O no hydrogen 2.910 N/A LYS 234.A N LEU 230.A O no hydrogen 3.293 N/A TYR 235.A N VAL 231.A O no hydrogen 3.135 N/A ASN 236.A N MET 233.A O no hydrogen 3.233 N/A TYR 237.A N ALA 232.A O no hydrogen 2.769 N/A GLU 238.A N THR 197.A O no hydrogen 2.812 N/A LEU 240.A N ASN 229.A OD1 no hydrogen 2.883 N/A THR 241.A N HIS 244.A ND1 no hydrogen 3.325 N/A GLN 242.A NE2 ASP 246.A OD1 no hydrogen 2.994 N/A HIS 244.A N THR 241.A OG1 no hydrogen 3.096 N/A VAL 245.A N THR 241.A O no hydrogen 2.960 N/A ASP 246.A N GLN 242.A O no hydrogen 2.919 N/A ILE 247.A N ASP 243.A O no hydrogen 3.005 N/A LEU 248.A N HIS 244.A O no hydrogen 3.204 N/A LEU 248.A N VAL 245.A O no hydrogen 3.290 N/A GLY 249.A N ASP 246.A O no hydrogen 3.208 N/A SER 252.A N LEU 248.A O no hydrogen 2.857 N/A SER 252.A OG ILE 257.A O no hydrogen 2.994 N/A ALA 253.A N GLY 249.A O no hydrogen 2.681 N/A GLN 254.A N PRO 250.A O no hydrogen 2.948 N/A THR 255.A N LEU 251.A O no hydrogen 3.252 N/A THR 255.A OG1 LEU 251.A O no hydrogen 2.831 N/A THR 255.A OG1 SER 252.A O no hydrogen 3.511 N/A ILE 257.A N THR 255.A OG1 no hydrogen 3.343 N/A MET 262.A N ALA 258.A O no hydrogen 2.962 N/A CYS 263.A N VAL 259.A O no hydrogen 2.789 N/A CYS 263.A SG VAL 259.A O no hydrogen 3.388 N/A ALA 264.A N LEU 260.A O no hydrogen 3.110 N/A SER 265.A N ASP 261.A O no hydrogen 3.121 N/A SER 265.A OG PHE 217.A O no hydrogen 3.372 N/A SER 265.A OG ASP 261.A O no hydrogen 3.472 N/A LEU 266.A N MET 262.A O no hydrogen 2.889 N/A LYS 267.A N CYS 263.A O no hydrogen 2.759 N/A LYS 267.A NZ ASP 227.A OD1.B no hydrogen 3.399 N/A LYS 267.A NZ ASP 227.A OD2.B no hydrogen 2.482 N/A GLU 268.A N ALA 264.A O no hydrogen 3.063 N/A LEU 269.A N SER 265.A O no hydrogen 2.939 N/A LEU 270.A N LEU 266.A O no hydrogen 2.835 N/A LEU 270.A N LYS 267.A O no hydrogen 2.994 N/A GLN 271.A N LYS 267.A O no hydrogen 3.098 N/A ASN 272.A N GLU 268.A O no hydrogen 2.938 N/A GLY 273.A N LEU 269.A O no hydrogen 2.899 N/A ARG 277.A N MET 274.A O no hydrogen 3.058 N/A ILE 279.A N SER 282.A O no hydrogen 2.830 N/A LEU 280.A N ASP 214.A OD2 no hydrogen 2.919 N/A SER 282.A N ILE 279.A O no hydrogen 2.982 N/A SER 282.A OG LEU 284.A O no hydrogen 2.802 N/A SER 282.A OG GLU 286.A OE1 no hydrogen 3.087 N/A LEU 284.A N SER 282.A OG no hydrogen 3.112 N/A THR 290.A N ASP 293.A OD2 no hydrogen 3.192 N/A ASP 293.A N THR 290.A OG1 no hydrogen 2.970 N/A VAL 294.A N THR 290.A O no hydrogen 3.097 N/A VAL 295.A N PRO 291.A O no hydrogen 3.170 N/A ARG 296.A N PHE 292.A O no hydrogen 2.956 N/A GLN 297.A N ASP 293.A O no hydrogen 3.002 N/A GLN 297.A NE2 ARG 4.A O no hydrogen 2.958 N/A CYS 298.A N VAL 294.A O no hydrogen 2.740 N/A SER 299.A OG VAL 295.A O no hydrogen 3.065 N/A