Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8hix_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 5.A N GLU 1.A O no hydrogen 3.179 N/A ARG 6.A N LEU 2.A O no hydrogen 2.890 N/A GLN 7.A N ASP 3.A O no hydrogen 2.941 N/A GLU 8.A N GLN 4.A O no hydrogen 2.878 N/A ALA 9.A N LEU 5.A O no hydrogen 2.893 N/A GLU 10.A N ARG 6.A O no hydrogen 2.883 N/A GLN 11.A N GLN 7.A O no hydrogen 2.858 N/A LEU 12.A N GLU 8.A O no hydrogen 2.989 N/A LYS 13.A N ALA 9.A O no hydrogen 2.857 N/A ASN 14.A N GLU 10.A O no hydrogen 2.874 N/A GLN 15.A N GLN 11.A O no hydrogen 2.918 N/A ILE 16.A N LEU 12.A O no hydrogen 2.917 N/A ARG 17.A N LYS 13.A O no hydrogen 2.825 N/A ASP 18.A N ASN 14.A O no hydrogen 2.851 N/A ALA 19.A N GLN 15.A O no hydrogen 2.906 N/A ARG 20.A N ILE 16.A O no hydrogen 2.886 N/A LYS 21.A N ARG 17.A O no hydrogen 2.881 N/A ALA 22.A N ASP 18.A O no hydrogen 2.858 N/A CYS 23.A N ALA 19.A O no hydrogen 2.906 N/A CYS 23.A SG ALA 19.A O no hydrogen 3.258 N/A CYS 23.A SG ALA 255.A O no hydrogen 4.043 N/A ALA 24.A N ARG 20.A O no hydrogen 2.777 N/A ASP 25.A N CYS 23.A O no hydrogen 2.713 N/A ALA 26.A N ASP 25.A OD1 no hydrogen 2.639 N/A GLN 30.A N THR 27.A O no hydrogen 3.312 N/A ILE 31.A N LEU 28.A O no hydrogen 3.202 N/A THR 32.A OG1 LEU 28.A O no hydrogen 3.451 N/A THR 32.A OG1 SER 29.A O no hydrogen 3.213 N/A ARG 46.A N ILE 336.A O no hydrogen 2.554 N/A ARG 47.A NE SER 82.A O no hydrogen 3.080 N/A ARG 47.A NE TYR 83.A O no hydrogen 3.026 N/A ARG 47.A NH2 TYR 83.A O no hydrogen 2.574 N/A LEU 49.A N LEU 334.A O no hydrogen 2.857 N/A ILE 56.A N SER 329.A O no hydrogen 3.133 N/A TYR 57.A N ALA 71.A O no hydrogen 2.788 N/A ALA 58.A N ALA 71.A O no hydrogen 2.996 N/A HIS 60.A N VAL 69.A O no hydrogen 2.916 N/A THR 63.A OG1 PRO 105.A O no hydrogen 2.660 N/A SER 65.A N GLY 62.A O no hydrogen 3.227 N/A ARG 66.A NE ASP 81.A OD2 no hydrogen 2.847 N/A ARG 66.A NH2 ASP 81.A OD2 no hydrogen 2.717 N/A LEU 68.A N TRP 80.A O no hydrogen 2.949 N/A VAL 69.A N HIS 60.A O no hydrogen 2.904 N/A SER 70.A N ILE 78.A O no hydrogen 2.899 N/A SER 70.A OG ALA 58.A O no hydrogen 3.207 N/A ALA 71.A N ALA 58.A O no hydrogen 2.820 N/A SER 72.A N LYS 76.A O no hydrogen 3.366 N/A SER 72.A OG LYS 55.A O no hydrogen 2.727 N/A SER 72.A OG ASP 74.A OD2 no hydrogen 2.932 N/A GLN 73.A N LYS 55.A O no hydrogen 2.912 N/A LEU 77.A N ILE 91.A O no hydrogen 2.919 N/A ILE 78.A N SER 70.A O no hydrogen 2.937 N/A ILE 79.A N HIS 89.A O no hydrogen 2.904 N/A TRP 80.A N LEU 68.A O no hydrogen 2.848 N/A ASP 81.A N ASN 86.A O no hydrogen 2.727 N/A SER 82.A N ARG 66.A O no hydrogen 2.723 N/A SER 82.A OG ARG 66.A O no hydrogen 2.853 N/A TYR 83.A N ASP 81.A OD1 no hydrogen 2.888 N/A THR 84.A N ASP 81.A OD1 no hydrogen 3.306 N/A THR 84.A OG1 ASN 86.A OD1 no hydrogen 2.629 N/A LYS 87.A NZ ARG 50.A O no hydrogen 3.253 N/A HIS 89.A N ILE 79.A O no hydrogen 3.047 N/A ILE 91.A N LEU 77.A O no hydrogen 2.840 N/A LEU 93.A N GLY 75.A O no hydrogen 2.557 N/A VAL 98.A N SER 96.A O no hydrogen 2.862 N/A MET 99.A N GLY 113.A O no hydrogen 2.875 N/A THR 100.A N GLY 113.A O no hydrogen 3.249 N/A ALA 102.A N ALA 111.A O no hydrogen 2.976 N/A TYR 103.A N HIS 60.A ND1 no hydrogen 2.957 N/A ALA 104.A N TYR 109.A O no hydrogen 2.929 N/A SER 106.A OG ASP 152.A OD1 no hydrogen 2.593 N/A SER 106.A OG ASP 152.A OD2 no hydrogen 2.941 N/A GLY 107.A N ALA 104.A O no hydrogen 2.757 N/A ASN 108.A N SER 106.A OG no hydrogen 3.081 N/A ASN 108.A ND2 ASP 152.A OD2 no hydrogen 3.487 N/A VAL 110.A N TYR 122.A O no hydrogen 2.920 N/A ALA 111.A N ALA 102.A O no hydrogen 3.027 N/A CYS 112.A N SER 120.A O no hydrogen 2.926 N/A CYS 112.A SG TYR 122.A OH no hydrogen 3.854 N/A GLY 113.A N THR 100.A O no hydrogen 3.389 N/A LEU 115.A N TRP 97.A O no hydrogen 3.116 N/A ASN 117.A N GLY 114.A O no hydrogen 2.845 N/A CYS 119.A N LEU 137.A O no hydrogen 2.943 N/A CYS 119.A SG CYS 112.A O no hydrogen 3.771 N/A SER 120.A N CYS 112.A O no hydrogen 2.877 N/A ILE 121.A N ARG 135.A O no hydrogen 2.985 N/A TYR 122.A N VAL 110.A O no hydrogen 2.837 N/A ASN 123.A N ARG 132.A O no hydrogen 2.971 N/A LEU 124.A N ASN 108.A O no hydrogen 2.804 N/A LYS 125.A N ASN 108.A O no hydrogen 3.370 N/A LYS 125.A NZ ASN 108.A OD1 no hydrogen 3.020 N/A SER 134.A N ILE 121.A O no hydrogen 2.412 N/A SER 134.A OG ILE 121.A O no hydrogen 2.944 N/A LEU 137.A N CYS 119.A O no hydrogen 2.834 N/A THR 141.A N ASP 161.A OD2 no hydrogen 2.427 N/A THR 141.A OG1 ASP 161.A OD2 no hydrogen 3.097 N/A LEU 144.A N GLY 114.A O no hydrogen 3.196 N/A SER 145.A N SER 158.A O no hydrogen 3.322 N/A SER 145.A OG SER 158.A OG no hydrogen 3.145 N/A SER 145.A OG VAL 185.A O no hydrogen 2.523 N/A SER 145.A OG MET 186.A O no hydrogen 3.283 N/A CYS 146.A SG LEU 188.A O no hydrogen 3.294 N/A ARG 148.A N VAL 156.A O no hydrogen 2.884 N/A ARG 148.A NH1 CYS 101.A O no hydrogen 3.432 N/A ARG 148.A NH1 CYS 147.A O no hydrogen 2.636 N/A LEU 150.A N GLN 154.A O no hydrogen 2.752 N/A ASP 151.A N GLN 154.A O no hydrogen 3.422 N/A ASN 153.A N ASP 151.A OD1 no hydrogen 2.597 N/A ILE 155.A N TRP 167.A O no hydrogen 3.041 N/A VAL 156.A N ARG 148.A O no hydrogen 2.897 N/A THR 157.A N ALA 165.A O no hydrogen 2.844 N/A SER 158.A N CYS 146.A O no hydrogen 2.553 N/A SER 158.A OG SER 145.A OG no hydrogen 3.145 N/A SER 158.A OG VAL 185.A O no hydrogen 2.817 N/A SER 159.A OG TYR 143.A O no hydrogen 2.459 N/A SER 159.A OG ASP 161.A OD1 no hydrogen 2.925 N/A GLY 160.A N TYR 143.A O no hydrogen 2.886 N/A ASP 161.A N SER 159.A OG no hydrogen 3.206 N/A THR 162.A OG1 ASP 161.A O no hydrogen 2.495 N/A THR 163.A N ASP 161.A OD1 no hydrogen 3.328 N/A THR 163.A OG1 ASP 161.A OD1 no hydrogen 3.014 N/A ALA 165.A N THR 157.A O no hydrogen 2.943 N/A LEU 166.A N THR 176.A O no hydrogen 2.884 N/A TRP 167.A N ILE 155.A O no hydrogen 2.826 N/A ASP 168.A N GLN 173.A O no hydrogen 3.077 N/A ILE 169.A N ASN 153.A O no hydrogen 2.930 N/A THR 171.A OG1 ASP 168.A OD2 no hydrogen 2.465 N/A GLY 172.A N ASP 168.A O no hydrogen 2.659 N/A THR 176.A N LEU 166.A O no hydrogen 2.993 N/A THR 177.A OG1 GLN 174.A OE1 no hydrogen 2.272 N/A PHE 178.A N CYS 164.A O no hydrogen 2.839 N/A HIS 181.A ND1 ASP 203.A OD2 no hydrogen 3.168 N/A HIS 181.A NE2 SER 199.A O no hydrogen 3.138 N/A HIS 181.A NE2 SER 199.A OG no hydrogen 2.957 N/A THR 182.A N ASP 203.A OD2 no hydrogen 2.777 N/A GLY 183.A N ASP 203.A OD2 no hydrogen 3.256 N/A MET 186.A N GLY 200.A O no hydrogen 2.957 N/A SER 189.A N VAL 198.A O no hydrogen 2.894 N/A THR 194.A N ALA 191.A O no hydrogen 3.241 N/A THR 194.A OG1 ASP 193.A O no hydrogen 2.642 N/A ARG 195.A N ASP 193.A OD1 no hydrogen 2.864 N/A PHE 197.A N TRP 209.A O no hydrogen 2.944 N/A VAL 198.A N SER 189.A O no hydrogen 3.164 N/A SER 199.A N LYS 207.A O no hydrogen 2.925 N/A SER 199.A OG HIS 181.A NE2 no hydrogen 2.957 N/A GLY 200.A N SER 187.A O no hydrogen 3.122 N/A ALA 201.A N SER 205.A O no hydrogen 2.954 N/A CYS 202.A N GLY 183.A O no hydrogen 2.795 N/A CYS 202.A N ASP 184.A O no hydrogen 2.972 N/A CYS 202.A SG ASP 184.A O no hydrogen 3.521 N/A ALA 204.A N ALA 201.A O no hydrogen 3.280 N/A SER 205.A N ASP 203.A OD1 no hydrogen 3.021 N/A SER 205.A OG ASP 203.A OD1 no hydrogen 2.378 N/A ALA 206.A N PHE 220.A O no hydrogen 2.897 N/A LYS 207.A N SER 199.A O no hydrogen 2.855 N/A LYS 207.A NZ GLY 180.A O no hydrogen 2.799 N/A LEU 208.A N GLN 218.A O no hydrogen 2.863 N/A TRP 209.A N PHE 197.A O no hydrogen 2.841 N/A TRP 209.A NE1 SER 199.A OG no hydrogen 3.133 N/A ASP 210.A N MET 215.A O no hydrogen 2.978 N/A VAL 211.A N ARG 195.A O no hydrogen 3.062 N/A GLU 213.A N ASP 210.A OD2 no hydrogen 2.484 N/A GLY 214.A N ASP 210.A O no hydrogen 3.227 N/A CYS 216.A SG LEU 208.A O no hydrogen 3.798 N/A CYS 216.A SG GLN 218.A O no hydrogen 3.236 N/A CYS 216.A SG THR 219.A OG1 no hydrogen 3.572 N/A GLN 218.A N LEU 208.A O no hydrogen 2.951 N/A GLN 218.A NE2 LEU 253.A O no hydrogen 2.869 N/A PHE 220.A N ALA 206.A O no hydrogen 2.879 N/A HIS 223.A NE2 THR 241.A OG1 no hydrogen 2.606 N/A ASP 226.A N SER 225.A OG no hydrogen 2.467 N/A ILE 227.A N ALA 201.A O no hydrogen 3.207 N/A ASN 228.A N GLY 242.A O no hydrogen 2.870 N/A ASN 228.A ND2 ILE 271.A O no hydrogen 2.555 N/A ALA 229.A N GLY 242.A O no hydrogen 3.177 N/A ILE 230.A N SER 187.A OG no hydrogen 3.269 N/A CYS 231.A N ALA 240.A O no hydrogen 3.089 N/A CYS 231.A SG ILE 230.A O no hydrogen 3.098 N/A CYS 231.A SG VAL 274.A O no hydrogen 3.146 N/A PHE 232.A N SER 189.A OG no hydrogen 3.051 N/A PHE 233.A N ALA 238.A O no hydrogen 2.734 N/A GLY 236.A N PHE 233.A O no hydrogen 3.030 N/A ASN 237.A N ASN 235.A OD1 no hydrogen 2.787 N/A PHE 239.A N PHE 251.A O no hydrogen 2.927 N/A ALA 240.A N CYS 231.A O no hydrogen 2.966 N/A THR 241.A N ARG 249.A O no hydrogen 2.822 N/A THR 241.A OG1 HIS 223.A NE2 no hydrogen 2.606 N/A THR 241.A OG1 ARG 249.A O no hydrogen 3.383 N/A GLY 242.A N ALA 229.A O no hydrogen 2.617 N/A SER 243.A N THR 247.A O no hydrogen 3.335 N/A SER 243.A OG THR 247.A O no hydrogen 3.399 N/A ASP 244.A N ASP 226.A O no hydrogen 2.523 N/A ASP 245.A N SER 243.A OG no hydrogen 3.419 N/A ALA 246.A N SER 243.A O no hydrogen 3.384 N/A THR 247.A OG1 CYS 248.A O no hydrogen 3.210 N/A THR 247.A OG1 TYR 262.A O no hydrogen 3.264 N/A CYS 248.A N TYR 262.A O no hydrogen 2.920 N/A ARG 249.A N THR 241.A O no hydrogen 2.905 N/A ARG 249.A NE GLU 258.A OE1 no hydrogen 3.054 N/A ARG 249.A NE GLU 258.A OE2 no hydrogen 3.353 N/A ARG 249.A NH1 HIS 223.A ND1 no hydrogen 3.075 N/A LEU 250.A N MET 260.A O no hydrogen 2.878 N/A PHE 251.A N PHE 239.A O no hydrogen 2.906 N/A ASP 252.A N GLN 257.A O no hydrogen 3.344 N/A LEU 253.A N ASN 237.A O no hydrogen 3.106 N/A ALA 255.A N ASP 252.A O no hydrogen 3.301 N/A ASP 256.A N ASP 252.A O no hydrogen 3.005 N/A LEU 259.A N LEU 250.A O no hydrogen 2.402 N/A MET 260.A N LEU 250.A O no hydrogen 3.018 N/A TYR 262.A N CYS 248.A O no hydrogen 2.812 N/A TYR 262.A OH ALA 297.A O no hydrogen 2.701 N/A ASN 266.A N ASN 266.A OD1 no hydrogen 2.498 N/A ILE 271.A N SER 243.A O no hydrogen 3.221 N/A THR 272.A N GLY 286.A O no hydrogen 3.419 N/A THR 272.A OG1 GLY 270.A O no hydrogen 3.534 N/A THR 272.A OG1 ASP 288.A OD1 no hydrogen 2.459 N/A SER 273.A OG SER 314.A O no hydrogen 2.884 N/A SER 275.A N LEU 284.A O no hydrogen 2.852 N/A SER 277.A N LEU 282.A O no hydrogen 3.004 N/A GLY 280.A N SER 277.A O no hydrogen 2.798 N/A ARG 281.A NH2 ASP 36.A O no hydrogen 2.856 N/A LEU 283.A N TRP 295.A O no hydrogen 2.895 N/A LEU 284.A N SER 275.A O no hydrogen 2.837 N/A ALA 285.A N ASN 293.A O no hydrogen 2.889 N/A GLY 286.A N SER 273.A O no hydrogen 2.462 N/A CYS 292.A N LEU 306.A O no hydrogen 2.937 N/A ASN 293.A N ALA 285.A O no hydrogen 2.926 N/A VAL 294.A N GLY 304.A O no hydrogen 2.859 N/A TRP 295.A N LEU 283.A O no hydrogen 2.816 N/A ASP 296.A N ASP 301.A O no hydrogen 2.914 N/A ALA 297.A N ARG 281.A O no hydrogen 2.990 N/A LYS 299.A NZ ASP 296.A OD1 no hydrogen 2.729 N/A ALA 300.A N ASP 296.A O no hydrogen 3.106 N/A GLY 304.A N VAL 294.A O no hydrogen 2.980 N/A LEU 306.A N CYS 292.A O no hydrogen 2.894 N/A HIS 309.A ND1 ASP 331.A OD1 no hydrogen 2.941 N/A HIS 309.A NE2 THR 327.A O no hydrogen 3.096 N/A HIS 309.A NE2 THR 327.A OG1 no hydrogen 2.681 N/A ASP 310.A N ASP 331.A OD2 no hydrogen 2.725 N/A ARG 312.A N ASN 311.A OD1 no hydrogen 2.930 N/A ARG 312.A NE ASP 288.A OD1 no hydrogen 2.890 N/A ARG 312.A NH2 THR 272.A OG1 no hydrogen 2.559 N/A ARG 312.A NH2 ASP 288.A OD1 no hydrogen 2.888 N/A VAL 313.A N TYR 287.A O no hydrogen 3.047 N/A SER 314.A OG ILE 56.A O no hydrogen 2.178 N/A GLY 317.A N ALA 326.A O no hydrogen 2.921 N/A THR 319.A N ALA 324.A O no hydrogen 3.268 N/A THR 319.A OG1 ALA 324.A O no hydrogen 3.569 N/A ASP 321.A N SER 65.A OG no hydrogen 2.943 N/A ALA 324.A N THR 319.A OG1 no hydrogen 3.359 N/A VAL 325.A N TRP 337.A O no hydrogen 2.897 N/A ALA 326.A N GLY 317.A O no hydrogen 2.899 N/A THR 327.A N LYS 335.A O no hydrogen 2.891 N/A THR 327.A OG1 HIS 309.A NE2 no hydrogen 2.681 N/A SER 329.A OG ASN 311.A O no hydrogen 3.097 N/A SER 329.A OG ARG 312.A O no hydrogen 2.480 N/A SER 329.A OG ASP 331.A OD1 no hydrogen 3.038 N/A TRP 330.A N ARG 312.A O no hydrogen 2.738 N/A ASP 331.A N SER 329.A OG no hydrogen 3.401 N/A SER 332.A OG ASP 331.A O no hydrogen 2.586 N/A LEU 334.A N LEU 49.A O no hydrogen 2.949 N/A LYS 335.A N THR 327.A O no hydrogen 2.912 N/A LYS 335.A NZ THR 48.A OG1 no hydrogen 3.159 N/A ILE 336.A N ARG 47.A O no hydrogen 2.955 N/A TRP 337.A N VAL 325.A O no hydrogen 2.832 N/A TRP 337.A NE1 THR 327.A OG1 no hydrogen 3.220 N/A