Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8hki_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 10.A N PRO 7.A O no hydrogen 3.103 N/A ARG 11.A N PRO 7.A O no hydrogen 3.333 N/A ARG 11.A NH2 ASP 244.A OD1 no hydrogen 3.148 N/A PHE 12.A N ALA 8.A O no hydrogen 3.048 N/A SER 13.A N GLN 9.A O no hydrogen 3.290 N/A SER 13.A OG HIS 62.A NE2 no hydrogen 3.214 N/A ASN 14.A N ILE 10.A O no hydrogen 2.941 N/A ILE 15.A N ARG 11.A O no hydrogen 2.838 N/A SER 16.A N PHE 12.A O no hydrogen 3.038 N/A SER 16.A OG PHE 12.A O no hydrogen 2.806 N/A ALA 17.A N SER 13.A O no hydrogen 3.178 N/A ALA 18.A N ASN 14.A O no hydrogen 2.864 N/A LYS 19.A N ILE 15.A O no hydrogen 2.644 N/A LYS 19.A NZ ASP 95.A OD1 no hydrogen 2.546 N/A ALA 20.A N SER 16.A O no hydrogen 2.967 N/A ASP 23.A N LYS 19.A O no hydrogen 2.965 N/A ILE 25.A N VAL 21.A O no hydrogen 3.470 N/A ARG 26.A N ALA 22.A O no hydrogen 3.045 N/A ARG 26.A NH2 GLU 178.A OE1 no hydrogen 3.416 N/A THR 27.A OG1 ALA 24.A O no hydrogen 3.187 N/A SER 28.A N ILE 25.A O no hydrogen 3.159 N/A SER 28.A OG MET 34.A O no hydrogen 3.182 N/A LEU 29.A N ARG 26.A O no hydrogen 3.150 N/A GLY 33.A N GLY 30.A O no hydrogen 3.279 N/A MET 34.A N THR 27.A O no hydrogen 2.811 N/A LYS 36.A N THR 48.A O no hydrogen 3.189 N/A LYS 36.A NZ ALA 24.A O no hydrogen 2.667 N/A LYS 36.A NZ THR 27.A OG1 no hydrogen 2.983 N/A GLN 39.A NE2 GLY 43.A O no hydrogen 3.501 N/A ASP 40.A N ASP 44.A O no hydrogen 2.899 N/A LYS 42.A N ASP 40.A OD2 no hydrogen 3.280 N/A GLY 43.A N ASP 40.A O no hydrogen 3.017 N/A VAL 45.A N ASP 44.A OD2 no hydrogen 2.593 N/A THR 53.A N ASP 50.A OD2 no hydrogen 2.542 N/A THR 53.A OG1 ASP 50.A OD2 no hydrogen 2.541 N/A ILE 54.A N ASP 50.A O no hydrogen 3.164 N/A LEU 55.A N GLY 51.A O no hydrogen 3.277 N/A LYS 56.A N ALA 52.A O no hydrogen 3.353 N/A MET 58.A N LEU 55.A O no hydrogen 3.250 N/A HIS 62.A NE2 SER 13.A OG no hydrogen 3.214 N/A ALA 64.A N HIS 62.A ND1 no hydrogen 3.217 N/A ARG 66.A N HIS 62.A O no hydrogen 3.064 N/A MET 67.A N PRO 63.A O no hydrogen 3.121 N/A LEU 68.A N ALA 64.A O no hydrogen 3.435 N/A VAL 69.A N ALA 65.A O no hydrogen 3.263 N/A GLU 70.A N ARG 66.A O no hydrogen 2.990 N/A LEU 71.A N MET 67.A O no hydrogen 2.763 N/A SER 72.A N LEU 68.A O no hydrogen 2.903 N/A SER 72.A OG LEU 68.A O no hydrogen 3.335 N/A SER 72.A OG VAL 69.A O no hydrogen 2.571 N/A LYS 73.A N VAL 69.A O no hydrogen 3.173 N/A ALA 74.A N GLU 70.A O no hydrogen 3.142 N/A ALA 74.A N LEU 71.A O no hydrogen 3.128 N/A GLN 75.A N LEU 71.A O no hydrogen 3.368 N/A GLN 75.A NE2 ASP 81.A O no hydrogen 3.319 N/A GLN 75.A NE2 VAL 225.A O no hydrogen 3.383 N/A GLN 75.A NE2 SER 228.A OG no hydrogen 2.578 N/A ASP 76.A N SER 72.A O no hydrogen 3.455 N/A ILE 77.A N LYS 73.A O no hydrogen 3.322 N/A ILE 77.A N ALA 74.A O no hydrogen 3.125 N/A GLU 78.A N ALA 74.A O no hydrogen 2.954 N/A ALA 79.A N GLN 75.A O no hydrogen 3.088 N/A GLY 80.A N GLN 75.A O no hydrogen 2.862 N/A GLY 82.A N ASP 81.A OD1 no hydrogen 2.531 N/A THR 83.A OG1 ASP 76.A OD1 no hydrogen 2.352 N/A ILE 88.A N THR 84.A O no hydrogen 3.107 N/A ILE 89.A N SER 85.A O no hydrogen 2.911 N/A ALA 90.A N VAL 86.A O no hydrogen 2.846 N/A GLY 91.A N VAL 87.A O no hydrogen 3.105 N/A SER 92.A N ILE 88.A O no hydrogen 3.006 N/A SER 92.A OG ILE 88.A O no hydrogen 3.261 N/A SER 92.A OG ILE 89.A O no hydrogen 2.890 N/A SER 92.A OG ALA 168.A O no hydrogen 3.335 N/A LEU 93.A N ILE 89.A O no hydrogen 2.957 N/A LEU 94.A N ALA 90.A O no hydrogen 3.252 N/A ASP 95.A N GLY 91.A O no hydrogen 3.004 N/A SER 96.A N SER 92.A O no hydrogen 2.889 N/A SER 96.A OG LEU 93.A O no hydrogen 2.758 N/A CYS 97.A N LEU 93.A O no hydrogen 2.673 N/A CYS 97.A SG LEU 93.A O no hydrogen 3.363 N/A THR 98.A N LEU 94.A O no hydrogen 3.224 N/A THR 98.A OG1 LEU 94.A O no hydrogen 3.065 N/A LYS 99.A N SER 96.A O no hydrogen 3.225 N/A LEU 101.A N CYS 97.A O no hydrogen 2.994 N/A GLN 102.A N THR 98.A O no hydrogen 3.328 N/A LYS 103.A N LYS 99.A O no hydrogen 3.299 N/A LYS 103.A N LEU 100.A O no hydrogen 3.012 N/A GLY 104.A N LEU 101.A O no hydrogen 3.120 N/A ILE 105.A N LEU 100.A O no hydrogen 3.458 N/A HIS 106.A ND1 THR 108.A OG1 no hydrogen 3.195 N/A THR 108.A OG1 HIS 106.A ND1 no hydrogen 3.195 N/A ILE 110.A N HIS 106.A O no hydrogen 3.319 N/A SER 111.A N PRO 107.A O no hydrogen 2.857 N/A GLU 112.A N THR 108.A O no hydrogen 3.064 N/A SER 113.A N ILE 109.A O no hydrogen 3.126 N/A SER 113.A OG ILE 109.A O no hydrogen 2.683 N/A PHE 114.A N ILE 110.A O no hydrogen 3.150 N/A GLN 115.A N SER 111.A O no hydrogen 3.314 N/A LYS 116.A N GLU 112.A O no hydrogen 3.365 N/A LYS 116.A NZ GLU 158.A OE1 no hydrogen 3.378 N/A LYS 116.A NZ GLU 158.A OE2 no hydrogen 2.595 N/A ALA 117.A N SER 113.A O no hydrogen 2.932 N/A LEU 118.A N PHE 114.A O no hydrogen 2.641 N/A GLU 119.A N GLN 115.A O no hydrogen 3.072 N/A LYS 120.A N LYS 116.A O no hydrogen 3.181 N/A GLY 121.A N ALA 117.A O no hydrogen 2.607 N/A ILE 122.A N LEU 118.A O no hydrogen 3.088 N/A GLU 123.A N GLU 119.A O no hydrogen 3.408 N/A ILE 124.A N LYS 120.A O no hydrogen 2.987 N/A LEU 125.A N GLY 121.A O no hydrogen 3.264 N/A THR 126.A N ILE 122.A O no hydrogen 3.007 N/A THR 126.A OG1 ILE 122.A O no hydrogen 2.639 N/A ASP 127.A N GLU 123.A O no hydrogen 3.187 N/A MET 128.A N ILE 124.A O no hydrogen 2.997 N/A ALA 131.A N LYS 129.A O no hydrogen 2.719 N/A ILE 133.A N GLN 221.A O no hydrogen 2.802 N/A ALA 138.A N GLY 135.A O no hydrogen 3.279 N/A ILE 141.A N GLY 137.A O no hydrogen 3.361 N/A ILE 141.A N ALA 138.A O no hydrogen 3.289 N/A GLU 142.A N ALA 138.A O no hydrogen 3.314 N/A LEU 143.A N PRO 139.A O no hydrogen 2.632 N/A ALA 144.A N GLU 140.A O no hydrogen 3.034 N/A LEU 145.A N ILE 141.A O no hydrogen 2.689 N/A LEU 145.A N GLU 142.A O no hydrogen 3.249 N/A ARG 146.A N GLU 142.A O no hydrogen 2.902 N/A ARG 146.A NE GLU 142.A OE2 no hydrogen 2.533 N/A ARG 146.A NH1 GLU 149.A OE2 no hydrogen 3.077 N/A LEU 147.A N LEU 143.A O no hydrogen 3.395 N/A THR 148.A OG1 ALA 144.A O no hydrogen 2.777 N/A GLU 149.A N ARG 146.A O no hydrogen 3.138 N/A TYR 150.A N ARG 146.A O no hydrogen 3.238 N/A SER 151.A N LEU 147.A O no hydrogen 3.031 N/A SER 151.A OG THR 148.A O no hydrogen 2.756 N/A ARG 152.A N GLU 149.A O no hydrogen 3.238 N/A THR 153.A N TYR 150.A O no hydrogen 3.036 N/A THR 153.A OG1 TYR 150.A O no hydrogen 2.672 N/A LEU 154.A N TYR 150.A O no hydrogen 3.128 N/A SER 159.A OG SER 151.A O no hydrogen 2.908 N/A CYS 161.A N MET 157.A O no hydrogen 3.225 N/A CYS 161.A SG MET 157.A O no hydrogen 3.377 N/A VAL 162.A N GLU 158.A O no hydrogen 2.638 N/A ARG 163.A N SER 159.A O no hydrogen 2.921 N/A ALA 164.A N TYR 160.A O no hydrogen 3.356 N/A PHE 165.A N CYS 161.A O no hydrogen 3.108 N/A ALA 166.A N VAL 162.A O no hydrogen 3.034 N/A ASP 167.A N ARG 163.A O no hydrogen 2.882 N/A ALA 168.A N ALA 164.A O no hydrogen 2.998 N/A MET 169.A N ALA 166.A O no hydrogen 3.192 N/A GLU 170.A N ASP 167.A O no hydrogen 3.296 N/A VAL 171.A N ALA 168.A O no hydrogen 3.332 N/A ILE 172.A N MET 169.A O no hydrogen 3.386 N/A SER 174.A N GLU 170.A O no hydrogen 3.136 N/A THR 175.A N VAL 171.A O no hydrogen 2.814 N/A THR 175.A OG1 VAL 171.A O no hydrogen 2.581 N/A LEU 176.A N ILE 172.A O no hydrogen 2.914 N/A ALA 177.A N PRO 173.A O no hydrogen 2.842 N/A GLU 178.A N SER 174.A O no hydrogen 3.266 N/A ASN 179.A N THR 175.A O no hydrogen 3.121 N/A ASN 179.A ND2 THR 27.A O no hydrogen 3.084 N/A ASN 179.A ND2 LEU 29.A O no hydrogen 2.786 N/A ALA 180.A N LEU 176.A O no hydrogen 2.959 N/A GLY 181.A N GLU 178.A O no hydrogen 3.141 N/A LEU 182.A N ALA 177.A O no hydrogen 2.835 N/A THR 187.A N ASN 183.A O no hydrogen 3.100 N/A THR 187.A OG1 ASN 183.A O no hydrogen 2.473 N/A VAL 188.A N PRO 184.A O no hydrogen 3.449 N/A THR 189.A N ILE 185.A O no hydrogen 2.820 N/A THR 189.A OG1 ILE 185.A O no hydrogen 2.989 N/A GLU 190.A N SER 186.A O no hydrogen 2.964 N/A LEU 191.A N THR 187.A O no hydrogen 3.204 N/A LEU 191.A N VAL 188.A O no hydrogen 3.273 N/A ARG 192.A N VAL 188.A O no hydrogen 3.185 N/A ARG 192.A NE GLU 170.A OE2 no hydrogen 3.123 N/A ARG 192.A NH2 GLU 170.A OE2 no hydrogen 3.130 N/A ASN 193.A N THR 189.A O no hydrogen 3.339 N/A ARG 194.A N GLU 190.A O no hydrogen 3.089 N/A ARG 194.A NE GLU 190.A OE2 no hydrogen 3.168 N/A ARG 194.A NH2 GLU 190.A OE2 no hydrogen 3.254 N/A HIS 195.A N LEU 191.A O no hydrogen 2.665 N/A HIS 195.A ND1 LEU 191.A O no hydrogen 2.672 N/A ALA 196.A N ARG 192.A O no hydrogen 2.913 N/A GLN 197.A N ASN 193.A O no hydrogen 3.137 N/A GLY 198.A N ARG 194.A O no hydrogen 2.602 N/A LYS 200.A NZ MET 128.A O no hydrogen 2.571 N/A THR 201.A OG1 GLU 199.A OE2 no hydrogen 2.652 N/A ALA 202.A N GLU 199.A O no hydrogen 3.511 N/A ILE 204.A N GLY 136.A O no hydrogen 3.147 N/A ASN 205.A N GLY 210.A O no hydrogen 3.023 N/A ARG 207.A NH2 GLU 217.A O no hydrogen 2.622 N/A LYS 208.A NZ GLU 217.A OE2 no hydrogen 3.029 N/A GLY 209.A N ASN 205.A O no hydrogen 2.846 N/A GLY 210.A N ASN 205.A O no hydrogen 3.227 N/A SER 212.A OG ILE 211.A O no hydrogen 2.661 N/A ILE 214.A N THR 201.A O no hydrogen 2.817 N/A GLU 216.A N ASN 213.A O no hydrogen 3.232 N/A GLU 217.A N ASN 213.A O no hydrogen 3.104 N/A GLU 217.A N ILE 214.A O no hydrogen 3.216 N/A GLN 221.A N ILE 133.A O no hydrogen 3.026 N/A GLN 221.A NE2 VAL 220.A O no hydrogen 3.343 N/A VAL 227.A N LEU 223.A O no hydrogen 3.092 N/A SER 228.A N LEU 224.A O no hydrogen 2.733 N/A SER 228.A OG LEU 224.A O no hydrogen 2.511 N/A SER 228.A OG VAL 225.A O no hydrogen 3.314 N/A ALA 229.A N VAL 225.A O no hydrogen 3.022 N/A LEU 230.A N SER 226.A O no hydrogen 3.293 N/A THR 231.A N VAL 227.A O no hydrogen 3.029 N/A THR 231.A OG1 VAL 227.A O no hydrogen 2.885 N/A LEU 232.A N SER 228.A O no hydrogen 2.966 N/A ALA 233.A N ALA 229.A O no hydrogen 2.900 N/A THR 234.A N LEU 230.A O no hydrogen 2.952 N/A THR 234.A OG1 LEU 230.A O no hydrogen 2.589 N/A GLU 235.A N THR 231.A O no hydrogen 3.142 N/A THR 236.A N LEU 232.A O no hydrogen 3.084 N/A THR 236.A OG1 LEU 232.A O no hydrogen 2.870 N/A VAL 237.A N ALA 233.A O no hydrogen 2.800 N/A ARG 238.A N THR 234.A O no hydrogen 2.704 N/A ARG 238.A NE SER 111.A OG no hydrogen 2.570 N/A ARG 238.A NH1 GLN 115.A OE1 no hydrogen 2.834 N/A ARG 238.A NH2 GLN 115.A OE1 no hydrogen 3.006 N/A SER 239.A N GLU 235.A O no hydrogen 3.119 N/A SER 239.A OG GLU 235.A O no hydrogen 2.818 N/A ILE 240.A N THR 236.A O no hydrogen 3.025 N/A LEU 241.A N VAL 237.A O no hydrogen 2.963 N/A LYS 242.A N ARG 238.A O no hydrogen 2.997 N/A ILE 243.A N ILE 240.A O no hydrogen 3.479 N/A