Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8i0k_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 1.A OG1 THR 1.A O no hydrogen 2.603 N/A THR 2.A OG1 TYR 288.A OH no hydrogen 3.009 N/A THR 4.A OG1 THR 1.A O no hydrogen 2.800 N/A TRP 6.A N THR 2.A O no hydrogen 2.963 N/A LEU 7.A N LEU 3.A O no hydrogen 2.823 N/A ASP 8.A N THR 4.A O no hydrogen 2.933 N/A ASN 9.A N SER 5.A O no hydrogen 2.936 N/A ASN 10.A N TRP 6.A O no hydrogen 2.936 N/A ASN 10.A N LEU 7.A O no hydrogen 3.148 N/A GLY 11.A N LEU 7.A O no hydrogen 2.908 N/A ALA 14.A N ASN 10.A O no hydrogen 3.434 N/A VAL 15.A N GLY 11.A O no hydrogen 2.974 N/A LYS 16.A N LYS 12.A O no hydrogen 3.008 N/A LYS 17.A N SER 13.A O no hydrogen 2.891 N/A LEU 18.A N ALA 14.A O no hydrogen 2.932 N/A LYS 19.A N VAL 15.A O no hydrogen 2.998 N/A ASN 20.A N LYS 16.A O no hydrogen 2.958 N/A SER 21.A N LYS 17.A O no hydrogen 2.898 N/A SER 21.A N LEU 18.A O no hydrogen 2.902 N/A SER 21.A OG LEU 18.A O no hydrogen 3.028 N/A SER 21.A OG ASP 293.A O no hydrogen 3.109 N/A LEU 22.A N LEU 18.A O no hydrogen 3.084 N/A ARG 25.A N SER 21.A O no hydrogen 3.347 N/A ARG 25.A NH2 ASP 293.A O no hydrogen 3.512 N/A LYS 26.A N LEU 22.A O no hydrogen 3.060 N/A GLU 27.A N PRO 23.A O no hydrogen 2.966 N/A LEU 28.A N LEU 24.A O no hydrogen 2.873 N/A ASP 29.A N ARG 25.A O no hydrogen 3.017 N/A ARG 30.A N LYS 26.A O no hydrogen 3.030 N/A ARG 30.A NE GLU 27.A OE1 no hydrogen 3.117 N/A ARG 30.A NH2 GLU 27.A OE1 no hydrogen 3.482 N/A ARG 30.A NH2 GLU 27.A OE2 no hydrogen 3.474 N/A LEU 31.A N GLU 27.A O no hydrogen 2.923 N/A LYS 32.A N LEU 28.A O no hydrogen 2.934 N/A ASP 33.A N ASP 29.A O no hydrogen 3.026 N/A GLU 34.A N ARG 30.A O no hydrogen 3.030 N/A LEU 35.A N LEU 31.A O no hydrogen 2.958 N/A SER 36.A N LYS 32.A O no hydrogen 2.912 N/A SER 36.A OG LEU 41.A O no hydrogen 3.422 N/A HIS 37.A N ASP 33.A O no hydrogen 2.963 N/A GLN 38.A N GLU 34.A O no hydrogen 2.967 N/A LEU 39.A N LEU 35.A O no hydrogen 3.254 N/A GLN 40.A N HIS 37.A O no hydrogen 3.314 N/A ILE 44.A N ASP 43.A OD1 no hydrogen 2.736 N/A ARG 45.A N ILE 81.A O no hydrogen 2.869 N/A TRP 46.A NE1 GLN 58.A OE1 no hydrogen 2.875 N/A HIS 54.A N GLY 51.A O no hydrogen 2.932 N/A ARG 55.A N GLY 51.A O no hydrogen 3.161 N/A ARG 55.A NE SER 49.A O no hydrogen 3.374 N/A ARG 55.A NH2 SER 49.A O no hydrogen 2.724 N/A CYS 56.A N ILE 52.A O no hydrogen 3.385 N/A CYS 56.A SG LEU 24.A O no hydrogen 3.850 N/A CYS 56.A SG ILE 52.A O no hydrogen 2.948 N/A SER 57.A N ALA 53.A O no hydrogen 3.404 N/A SER 57.A OG HIS 54.A ND1 no hydrogen 3.272 N/A SER 57.A OG HIS 54.A O no hydrogen 2.641 N/A GLN 58.A N HIS 54.A O no hydrogen 2.972 N/A LEU 59.A N ARG 55.A O no hydrogen 2.990 N/A HIS 60.A N CYS 56.A O no hydrogen 2.913 N/A SER 61.A N SER 57.A O no hydrogen 2.927 N/A SER 61.A OG GLN 58.A O no hydrogen 2.751 N/A LEU 62.A N GLN 58.A O no hydrogen 3.002 N/A SER 63.A N LEU 59.A O no hydrogen 2.939 N/A ARG 64.A N HIS 60.A O no hydrogen 2.952 N/A LEU 65.A N SER 61.A O no hydrogen 2.966 N/A ALA 66.A N LEU 62.A O no hydrogen 2.943 N/A GLN 67.A N SER 63.A O no hydrogen 2.930 N/A GLN 68.A N ARG 64.A O no hydrogen 2.996 N/A ASN 69.A N LEU 65.A O no hydrogen 2.990 N/A LYS 74.A N LEU 70.A O no hydrogen 2.898 N/A LYS 74.A N GLU 71.A O no hydrogen 3.181 N/A LYS 75.A N THR 72.A O no hydrogen 3.262 N/A LYS 77.A NZ GLN 40.A OE1 no hydrogen 2.630 N/A GLY 78.A N GLN 40.A O no hydrogen 3.200 N/A CYS 79.A N ALA 76.A O no hydrogen 3.284 N/A CYS 79.A SG LYS 77.A O no hydrogen 3.671 N/A THR 80.A OG1 ASP 43.A O no hydrogen 2.829 N/A ILE 81.A N ASP 43.A O no hydrogen 3.032 N/A ILE 82.A N VAL 95.A O no hydrogen 2.909 N/A PHE 83.A N ARG 45.A O no hydrogen 3.089 N/A THR 84.A N LEU 97.A O no hydrogen 2.889 N/A THR 84.A OG1 ARG 86.A O no hydrogen 2.550 N/A THR 84.A OG1 MET 96.A O no hydrogen 3.557 N/A THR 84.A OG1 LEU 97.A O no hydrogen 3.431 N/A ARG 86.A N THR 84.A OG1 no hydrogen 3.348 N/A ARG 86.A NH1 THR 150.A OG1 no hydrogen 3.351 N/A SER 87.A OG ASP 101.A OD2 no hydrogen 2.766 N/A SER 90.A N HIS 94.A O no hydrogen 3.000 N/A GLY 93.A N SER 90.A O no hydrogen 3.380 N/A HIS 94.A N SER 90.A OG no hydrogen 2.990 N/A MET 96.A N GLY 88.A O no hydrogen 3.065 N/A THR 99.A N THR 84.A O no hydrogen 2.766 N/A ASP 101.A N GLY 98.A O no hydrogen 3.324 N/A HIS 105.A N VAL 102.A O no hydrogen 2.933 N/A TRP 106.A N VAL 102.A O no hydrogen 3.347 N/A THR 107.A N HIS 103.A O no hydrogen 2.937 N/A THR 107.A OG1 HIS 103.A O no hydrogen 2.946 N/A LYS 108.A NZ HIS 104.A ND1 no hydrogen 3.309 N/A LEU 109.A N HIS 105.A O no hydrogen 3.448 N/A PHE 110.A N TRP 106.A O no hydrogen 2.983 N/A GLU 111.A N LYS 108.A O no hydrogen 3.294 N/A ARG 112.A N LEU 109.A O no hydrogen 3.199 N/A SER 115.A OG ARG 112.A O no hydrogen 2.866 N/A TYR 116.A N ARG 112.A O no hydrogen 3.404 N/A TYR 116.A OH GLU 152.A OE2 no hydrogen 3.391 N/A PHE 117.A N LEU 113.A O no hydrogen 2.908 N/A ASP 118.A N PRO 114.A O no hydrogen 2.908 N/A LEU 119.A N SER 115.A O no hydrogen 2.946 N/A GLN 120.A N TYR 116.A O no hydrogen 2.964 N/A ARG 121.A N ASP 118.A O no hydrogen 3.145 N/A ARG 122.A NH2 ASP 118.A OD2 no hydrogen 3.428 N/A LEU 123.A N LEU 119.A O no hydrogen 2.995 N/A MET 124.A N GLN 120.A O no hydrogen 2.911 N/A ILE 125.A N ARG 121.A O no hydrogen 2.925 N/A LEU 126.A N ARG 122.A O no hydrogen 2.948 N/A GLU 127.A N LEU 123.A O no hydrogen 2.893 N/A ASP 128.A N MET 124.A O no hydrogen 2.932 N/A GLN 129.A N ILE 125.A O no hydrogen 2.929 N/A ILE 130.A N LEU 126.A O no hydrogen 2.945 N/A SER 131.A N GLU 127.A O no hydrogen 2.874 N/A SER 131.A OG GLU 127.A O no hydrogen 3.381 N/A SER 131.A OG ASP 128.A O no hydrogen 2.416 N/A TYR 132.A N ASP 128.A O no hydrogen 2.920 N/A LEU 133.A N GLN 129.A O no hydrogen 2.916 N/A LEU 134.A N ILE 130.A O no hydrogen 3.485 N/A VAL 140.A N MET 182.A O no hydrogen 3.455 N/A TYR 141.A OH PRO 147.A O no hydrogen 2.823 N/A LEU 149.A N TYR 141.A OH no hydrogen 3.082 N/A LEU 151.A N MET 89.A O no hydrogen 2.935 N/A GLU 152.A N GLU 152.A OE1 no hydrogen 3.002 N/A TYR 154.A N THR 150.A O no hydrogen 3.164 N/A TYR 155.A N LEU 151.A O no hydrogen 2.928 N/A SER 156.A N GLU 152.A O no hydrogen 2.870 N/A SER 156.A OG GLU 152.A O no hydrogen 3.022 N/A LEU 157.A N GLU 153.A O no hydrogen 2.931 N/A LEU 158.A N TYR 154.A O no hydrogen 2.953 N/A ASP 159.A N TYR 155.A O no hydrogen 2.874 N/A VAL 160.A N SER 156.A O no hydrogen 2.886 N/A PHE 161.A N LEU 157.A O no hydrogen 2.963 N/A TYR 162.A N LEU 158.A O no hydrogen 2.952 N/A ASN 163.A N ASP 159.A O no hydrogen 2.885 N/A ARG 164.A N VAL 160.A O no hydrogen 2.896 N/A LEU 165.A N PHE 161.A O no hydrogen 2.953 N/A LEU 166.A N TYR 162.A O no hydrogen 2.918 N/A LYS 167.A N ASN 163.A O no hydrogen 3.481 N/A MET 182.A N GLN 138.A O no hydrogen 3.148 N/A ILE 183.A N PHE 199.A O no hydrogen 2.649 N/A ARG 188.A NH1 SER 186.A O no hydrogen 2.732 N/A HIS 194.A N HIS 198.A O no hydrogen 3.110 N/A LEU 196.A N HIS 194.A ND1 no hydrogen 3.125 N/A PHE 199.A N GLN 181.A O no hydrogen 3.337 N/A THR 203.A OG1 ASP 187.A OD2 no hydrogen 2.473 N/A CYS 205.A SG PRO 202.A O no hydrogen 3.324 N/A LEU 210.A N ASP 206.A O no hydrogen 2.801 N/A GLN 211.A N PRO 207.A O no hydrogen 2.890 N/A TRP 212.A N ALA 208.A O no hydrogen 2.941 N/A PHE 213.A N ASN 209.A O no hydrogen 2.894 N/A ILE 214.A N LEU 210.A O no hydrogen 2.926 N/A LEU 215.A N GLN 211.A O no hydrogen 2.952 N/A LYS 217.A NZ PHE 213.A O no hydrogen 2.296 N/A GLN 220.A N GLN 220.A OE1 no hydrogen 2.619 N/A ARG 222.A N ALA 218.A O no hydrogen 2.946 N/A GLU 223.A N GLN 219.A O no hydrogen 2.932 N/A ASN 224.A N GLN 220.A O no hydrogen 2.937 N/A ASN 224.A ND2 GLU 195.A O no hydrogen 2.739 N/A MET 225.A N ALA 221.A O no hydrogen 2.957 N/A LYS 226.A N GLU 223.A O no hydrogen 3.257 N/A ARG 227.A N GLU 223.A O no hydrogen 3.045 N/A LYS 228.A N ASN 224.A O no hydrogen 2.982 N/A GLU 230.A N LYS 226.A O no hydrogen 3.053 N/A LEU 231.A N ARG 227.A O no hydrogen 2.983 N/A LYS 232.A N LYS 228.A O no hydrogen 2.954 N/A VAL 233.A N GLU 229.A O no hydrogen 2.944 N/A ILE 234.A N GLU 230.A O no hydrogen 3.042 N/A GLU 235.A N LEU 231.A O no hydrogen 2.926 N/A ASN 236.A N LYS 232.A O no hydrogen 2.947 N/A GLU 237.A N VAL 233.A O no hydrogen 3.090 N/A LEU 238.A N ILE 234.A O no hydrogen 2.955 N/A ILE 239.A N GLU 235.A O no hydrogen 2.910 N/A GLN 240.A N ASN 236.A O no hydrogen 3.025 N/A ALA 241.A N GLU 237.A O no hydrogen 2.973 N/A SER 242.A N LEU 238.A O no hydrogen 2.947 N/A THR 243.A N ILE 239.A O no hydrogen 3.435 N/A THR 243.A OG1 ILE 239.A O no hydrogen 3.404 N/A THR 243.A OG1 GLN 240.A O no hydrogen 2.603 N/A LYS 244.A N GLN 240.A O no hydrogen 3.007 N/A LYS 245.A N ALA 241.A O no hydrogen 2.902 N/A LYS 245.A NZ LEU 270.A O no hydrogen 2.483 N/A LYS 245.A NZ GLN 272.A O no hydrogen 3.006 N/A PHE 246.A N SER 242.A O no hydrogen 2.947 N/A SER 247.A N THR 243.A O no hydrogen 2.847 N/A GLU 249.A N MET 280.A O no hydrogen 3.370 N/A TYR 252.A N LEU 282.A O no hydrogen 3.311 N/A LYS 253.A NZ ILE 257.A O no hydrogen 2.627 N/A GLU 254.A N ILE 284.A O no hydrogen 3.088 N/A SER 256.A OG HIS 286.A NE2 no hydrogen 2.718 N/A ILE 257.A N GLU 254.A O no hydrogen 3.081 N/A SER 258.A N GLN 261.A OE1 no hydrogen 2.447 N/A ILE 260.A N SER 258.A OG no hydrogen 3.339 N/A MET 262.A N SER 258.A O no hydrogen 3.180 N/A VAL 263.A N SER 259.A O no hydrogen 2.882 N/A ASP 264.A N ILE 260.A O no hydrogen 3.007 N/A CYS 265.A N GLN 261.A O no hydrogen 2.867 N/A CYS 266.A N MET 262.A O no hydrogen 2.909 N/A CYS 266.A SG LEU 238.A O no hydrogen 3.177 N/A LYS 267.A N VAL 263.A O no hydrogen 2.952 N/A ARG 268.A N ASP 264.A O no hydrogen 2.956 N/A LEU 269.A N CYS 265.A O no hydrogen 2.945 N/A LEU 270.A N CYS 266.A O no hydrogen 2.925 N/A GLN 272.A N LEU 269.A O no hydrogen 2.840 N/A GLY 279.A N SER 247.A O no hydrogen 2.754 N/A LEU 282.A N LYS 250.A O no hydrogen 3.480 N/A CYS 283.A N LEU 296.A O no hydrogen 3.105 N/A CYS 283.A SG LEU 296.A O no hydrogen 3.397 N/A ILE 284.A N TYR 252.A O no hydrogen 2.934 N/A SER 285.A N ILE 298.A O no hydrogen 3.285 N/A HIS 286.A N SER 285.A OG no hydrogen 2.629 N/A HIS 286.A NE2 SER 256.A OG no hydrogen 2.718 N/A TYR 288.A OH THR 2.A OG1 no hydrogen 3.009 N/A SER 289.A N CYS 297.A O no hydrogen 3.327 N/A SER 289.A OG VAL 290.A O no hydrogen 3.537 N/A MET 291.A N ASP 295.A O no hydrogen 2.689 N/A GLY 294.A N MET 291.A O no hydrogen 3.084 N/A LEU 296.A N HIS 281.A O no hydrogen 3.183 N/A CYS 297.A N SER 289.A O no hydrogen 2.752 N/A ILE 298.A N CYS 283.A O no hydrogen 3.294 N/A