Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8i9u_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 1.A N ASP 1.A OD1 no hydrogen 2.413 N/A ARG 2.A NH1 ARG 2.A O no hydrogen 3.398 N/A ALA 6.A N ARG 2.A O no hydrogen 3.226 N/A GLN 7.A N ASP 3.A O no hydrogen 2.903 N/A ILE 8.A N LYS 4.A O no hydrogen 2.919 N/A ARG 9.A N PRO 5.A O no hydrogen 2.895 N/A ARG 9.A NH2 ASP 508.A OD2 no hydrogen 2.552 N/A PHE 10.A N ALA 6.A O no hydrogen 2.899 N/A SER 11.A N GLN 7.A O no hydrogen 2.897 N/A SER 11.A OG ILE 8.A O no hydrogen 2.997 N/A SER 11.A OG ASN 12.A OD1 no hydrogen 3.217 N/A ASN 12.A N ILE 8.A O no hydrogen 2.922 N/A ILE 13.A N ARG 9.A O no hydrogen 2.893 N/A SER 14.A N PHE 10.A O no hydrogen 2.898 N/A SER 14.A OG PHE 10.A O no hydrogen 3.166 N/A ALA 15.A N SER 11.A O no hydrogen 2.909 N/A ALA 16.A N ASN 12.A O no hydrogen 2.915 N/A LYS 17.A N ILE 13.A O no hydrogen 2.883 N/A LYS 17.A NZ ASP 93.A OD2 no hydrogen 2.976 N/A ALA 18.A N SER 14.A O no hydrogen 2.905 N/A VAL 19.A N ALA 15.A O no hydrogen 2.914 N/A ALA 20.A N ALA 16.A O no hydrogen 2.903 N/A ASP 21.A N LYS 17.A O no hydrogen 2.883 N/A ALA 22.A N ALA 18.A O no hydrogen 2.908 N/A MET 32.A N THR 25.A O no hydrogen 3.234 N/A LYS 34.A N THR 46.A O no hydrogen 2.898 N/A ILE 36.A N THR 44.A O no hydrogen 2.894 N/A ASP 38.A N ASP 42.A O no hydrogen 2.543 N/A GLY 39.A N ASP 38.A OD1 no hydrogen 2.580 N/A THR 44.A N ILE 36.A O no hydrogen 2.904 N/A THR 44.A OG1 ASP 42.A OD2 no hydrogen 3.563 N/A THR 46.A N LYS 34.A O no hydrogen 2.907 N/A ALA 50.A N ASP 48.A OD2 no hydrogen 3.177 N/A LEU 53.A N GLY 49.A O no hydrogen 2.905 N/A LYS 54.A N ALA 50.A O no hydrogen 2.902 N/A GLN 55.A N THR 51.A O no hydrogen 2.898 N/A MET 56.A N ILE 52.A O no hydrogen 3.312 N/A ALA 62.A N HIS 60.A ND1 no hydrogen 3.095 N/A ARG 64.A N HIS 60.A O no hydrogen 2.957 N/A MET 65.A N PRO 61.A O no hydrogen 2.903 N/A LEU 66.A N ALA 62.A O no hydrogen 2.901 N/A VAL 67.A N ALA 63.A O no hydrogen 2.907 N/A GLU 68.A N ARG 64.A O no hydrogen 2.904 N/A LEU 69.A N MET 65.A O no hydrogen 2.891 N/A SER 70.A N LEU 66.A O no hydrogen 2.907 N/A SER 70.A OG THR 81.A OG1 no hydrogen 2.951 N/A LYS 71.A N VAL 67.A O no hydrogen 2.908 N/A ALA 72.A N GLU 68.A O no hydrogen 2.895 N/A GLN 73.A N LEU 69.A O no hydrogen 2.903 N/A GLN 73.A NE2 ASP 79.A O no hydrogen 3.389 N/A ASP 74.A N SER 70.A O no hydrogen 2.910 N/A ILE 75.A N LYS 71.A O no hydrogen 2.901 N/A GLU 76.A N ALA 72.A O no hydrogen 2.901 N/A ALA 77.A N GLN 73.A O no hydrogen 3.193 N/A THR 81.A OG1 THR 81.A O no hydrogen 2.561 N/A ILE 87.A N SER 83.A O no hydrogen 2.915 N/A ALA 88.A N VAL 84.A O no hydrogen 2.896 N/A GLY 89.A N VAL 85.A O no hydrogen 2.895 N/A SER 90.A N ILE 86.A O no hydrogen 2.910 N/A SER 90.A OG ILE 86.A O no hydrogen 3.057 N/A SER 90.A OG ILE 87.A O no hydrogen 2.667 N/A LEU 91.A N ILE 87.A O no hydrogen 2.914 N/A LEU 92.A N ALA 88.A O no hydrogen 2.892 N/A ASP 93.A N GLY 89.A O no hydrogen 2.894 N/A SER 94.A N SER 90.A O no hydrogen 2.926 N/A SER 94.A OG SER 90.A O no hydrogen 3.142 N/A CYS 95.A N LEU 91.A O no hydrogen 2.887 N/A CYS 95.A SG LEU 91.A O no hydrogen 3.521 N/A THR 96.A N LEU 92.A O no hydrogen 2.895 N/A THR 96.A OG1 LEU 92.A O no hydrogen 2.856 N/A LYS 97.A N ASP 93.A O no hydrogen 3.524 N/A LEU 98.A N SER 94.A O no hydrogen 2.926 N/A LEU 99.A N CYS 95.A O no hydrogen 2.874 N/A GLN 100.A N THR 96.A O no hydrogen 2.915 N/A THR 106.A OG1 HIS 104.A ND1 no hydrogen 3.349 N/A ILE 108.A N HIS 104.A O no hydrogen 3.490 N/A SER 109.A N PRO 105.A O no hydrogen 2.894 N/A SER 109.A OG PRO 105.A O no hydrogen 2.887 N/A GLU 110.A N THR 106.A O no hydrogen 2.920 N/A SER 111.A N ILE 107.A O no hydrogen 2.896 N/A SER 111.A OG ILE 107.A O no hydrogen 2.525 N/A SER 111.A OG GLU 422.A O no hydrogen 3.492 N/A PHE 112.A N ILE 108.A O no hydrogen 2.895 N/A GLN 113.A N SER 109.A O no hydrogen 2.908 N/A LYS 114.A N GLU 110.A O no hydrogen 2.920 N/A ALA 115.A N SER 111.A O no hydrogen 2.894 N/A LEU 116.A N PHE 112.A O no hydrogen 2.888 N/A GLU 117.A N GLN 113.A O no hydrogen 2.922 N/A LYS 118.A N LYS 114.A O no hydrogen 2.914 N/A GLY 119.A N ALA 115.A O no hydrogen 2.890 N/A ILE 120.A N LEU 116.A O no hydrogen 2.898 N/A GLU 121.A N GLU 117.A O no hydrogen 2.930 N/A ILE 122.A N LYS 118.A O no hydrogen 2.904 N/A LEU 123.A N GLY 119.A O no hydrogen 2.894 N/A THR 124.A N ILE 120.A O no hydrogen 2.922 N/A THR 124.A OG1 ILE 120.A O no hydrogen 3.010 N/A THR 124.A OG1 GLU 121.A O no hydrogen 2.725 N/A ASP 125.A N GLU 121.A O no hydrogen 2.910 N/A MET 126.A N ILE 122.A O no hydrogen 2.895 N/A SER 127.A N LEU 123.A O no hydrogen 3.257 N/A SER 127.A OG LEU 123.A O no hydrogen 3.348 N/A SER 127.A OG THR 124.A O no hydrogen 3.477 N/A ASP 134.A N ASP 134.A OD1 no hydrogen 2.553 N/A THR 137.A OG1 GLU 131.A O no hydrogen 3.187 N/A THR 137.A OG1 ASP 134.A OD1 no hydrogen 2.579 N/A LEU 139.A N ARG 135.A O no hydrogen 2.956 N/A ASN 140.A N GLU 136.A O no hydrogen 2.907 N/A SER 141.A N THR 137.A O no hydrogen 2.900 N/A SER 141.A OG THR 137.A O no hydrogen 2.844 N/A ALA 142.A N LEU 138.A O no hydrogen 2.903 N/A THR 143.A N LEU 139.A O no hydrogen 2.904 N/A THR 144.A N ASN 140.A O no hydrogen 2.903 N/A THR 144.A OG1 ASN 140.A O no hydrogen 2.363 N/A SER 145.A N SER 141.A O no hydrogen 2.905 N/A SER 145.A OG SER 141.A O no hydrogen 3.329 N/A SER 148.A OG SER 148.A O no hydrogen 2.458 N/A SER 155.A N VAL 151.A O no hydrogen 3.025 N/A SER 155.A OG VAL 151.A O no hydrogen 2.808 N/A SER 156.A N SER 152.A O no hydrogen 2.905 N/A SER 156.A OG SER 152.A O no hydrogen 3.449 N/A SER 156.A OG GLN 153.A O no hydrogen 2.712 N/A LEU 157.A N GLN 153.A O no hydrogen 2.901 N/A LEU 158.A N TYR 154.A O no hydrogen 2.909 N/A SER 159.A N SER 155.A O no hydrogen 2.901 N/A SER 159.A OG SER 155.A O no hydrogen 3.197 N/A SER 159.A OG SER 156.A O no hydrogen 2.530 N/A SER 162.A N LEU 158.A O no hydrogen 2.738 N/A SER 162.A OG SER 159.A O no hydrogen 2.705 N/A VAL 163.A N SER 159.A O no hydrogen 2.906 N/A ASN 164.A N PRO 160.A O no hydrogen 2.913 N/A ALA 165.A N MET 161.A O no hydrogen 2.891 N/A VAL 166.A N SER 162.A O no hydrogen 2.910 N/A LYS 168.A N ALA 165.A O no hydrogen 3.429 N/A ALA 173.A N ASP 171.A O no hydrogen 2.824 N/A THR 174.A OG1 THR 176.A O no hydrogen 2.660 N/A THR 176.A OG1 SER 177.A O no hydrogen 3.464 N/A SER 177.A OG ASP 179.A OD1 no hydrogen 2.331 N/A ASP 179.A N SER 177.A OG no hydrogen 3.233 N/A ARG 181.A N VAL 178.A O no hydrogen 3.374 N/A LYS 184.A NZ ASP 307.A OD1 no hydrogen 2.992 N/A LYS 188.A NZ THR 205.A OG1 no hydrogen 2.904 N/A LYS 188.A NZ LYS 347.A O no hydrogen 2.635 N/A ASP 195.A N THR 192.A O no hydrogen 3.364 N/A CYS 196.A N ASP 194.A O no hydrogen 3.028 N/A CYS 196.A SG ASP 194.A O no hydrogen 4.039 N/A VAL 199.A N THR 362.A O no hydrogen 2.906 N/A LEU 202.A N ILE 351.A O no hydrogen 3.166 N/A LEU 204.A N LEU 349.A O no hydrogen 2.883 N/A THR 205.A OG1 THR 205.A O no hydrogen 2.478 N/A THR 205.A OG1 LYS 347.A O no hydrogen 2.554 N/A LYS 207.A N GLN 206.A OE1 no hydrogen 3.005 N/A LYS 207.A NZ SER 209.A O no hydrogen 2.856 N/A ASN 210.A N SER 209.A OG no hydrogen 2.576 N/A LYS 220.A N LYS 218.A O no hydrogen 2.599 N/A LYS 220.A NZ SER 333.A O no hydrogen 3.065 N/A ILE 224.A N GLY 222.A O no hydrogen 2.827 N/A LYS 232.A NZ ASP 282.A OD1 no hydrogen 3.375 N/A LYS 232.A NZ ASP 282.A OD2 no hydrogen 2.706 N/A THR 233.A OG1 MET 235.A O no hydrogen 2.598 N/A SER 242.A N GLN 246.A OE1 no hydrogen 3.230 N/A SER 242.A OG VAL 241.A O no hydrogen 2.677 N/A ASP 243.A N ASP 243.A OD2 no hydrogen 2.461 N/A MET 247.A N TYR 244.A O no hydrogen 3.389 N/A ARG 249.A N ALA 245.A O no hydrogen 3.170 N/A VAL 250.A N GLN 246.A O no hydrogen 3.231 N/A LEU 251.A N MET 247.A O no hydrogen 2.908 N/A ARG 252.A N ASP 248.A O no hydrogen 2.899 N/A GLU 253.A N ARG 249.A O no hydrogen 2.905 N/A GLU 254.A N VAL 250.A O no hydrogen 2.896 N/A ARG 255.A N LEU 251.A O no hydrogen 2.904 N/A ALA 256.A N ARG 252.A O no hydrogen 2.667 N/A VAL 262.A N ILE 258.A O no hydrogen 2.916 N/A LYS 263.A N LEU 259.A O no hydrogen 2.882 N/A GLN 264.A N ASN 260.A O no hydrogen 2.913 N/A ILE 265.A N LEU 261.A O no hydrogen 2.907 N/A LYS 266.A N VAL 262.A O no hydrogen 2.898 N/A THR 268.A N ILE 265.A O no hydrogen 3.464 N/A CYS 270.A SG LYS 218.A O no hydrogen 3.441 N/A VAL 272.A N CYS 270.A O no hydrogen 2.909 N/A GLN 276.A NE2 GLU 304.A O no hydrogen 3.570 N/A ALA 283.A N ASP 282.A OD1 no hydrogen 2.775 N/A HIS 290.A N ASP 286.A O no hydrogen 2.906 N/A PHE 291.A N LEU 287.A O no hydrogen 2.909 N/A LEU 292.A N ALA 288.A O no hydrogen 2.896 N/A ASN 293.A N HIS 290.A O no hydrogen 3.292 N/A LYS 296.A NZ ILE 297.A O no hydrogen 3.558 N/A ILE 308.A N GLU 304.A O no hydrogen 3.407 N/A GLU 309.A N ARG 305.A O no hydrogen 2.915 N/A PHE 310.A N GLU 306.A O no hydrogen 2.887 N/A ILE 311.A N ASP 307.A O no hydrogen 2.906 N/A CYS 312.A N ILE 308.A O no hydrogen 2.901 N/A CYS 312.A SG GLU 309.A O no hydrogen 3.245 N/A LYS 313.A N PHE 310.A O no hydrogen 3.295 N/A THR 314.A N PHE 310.A O no hydrogen 2.903 N/A THR 314.A OG1 PHE 310.A O no hydrogen 2.882 N/A ILE 315.A N ILE 311.A O no hydrogen 3.299 N/A THR 317.A N CYS 312.A O no hydrogen 3.433 N/A GLN 325.A NE2 THR 327.A OG1 no hydrogen 3.349 N/A ASN 341.A ND2 GLY 344.A O no hydrogen 3.211 N/A LYS 347.A NZ GLU 339.A O no hydrogen 3.125 N/A LEU 349.A N LEU 204.A O no hydrogen 2.904 N/A ILE 351.A N LEU 202.A O no hydrogen 2.920 N/A THR 362.A N VAL 199.A O no hydrogen 2.898 N/A THR 362.A OG1 VAL 199.A O no hydrogen 3.566 N/A GLU 377.A N ILE 373.A O no hydrogen 2.898 N/A ARG 378.A N GLU 374.A O no hydrogen 2.909 N/A SER 379.A N GLU 375.A O no hydrogen 2.889 N/A SER 379.A OG ALA 376.A O no hydrogen 2.580 N/A ILE 380.A N ALA 376.A O no hydrogen 2.910 N/A HIS 381.A N GLU 377.A O no hydrogen 2.897 N/A ASP 382.A N ARG 378.A O no hydrogen 2.925 N/A ALA 383.A N SER 379.A O no hydrogen 2.884 N/A LEU 384.A N ILE 380.A O no hydrogen 2.920 N/A CYS 385.A N HIS 381.A O no hydrogen 2.919 N/A CYS 385.A SG HIS 381.A ND1 no hydrogen 3.695 N/A CYS 385.A SG HIS 381.A O no hydrogen 3.395 N/A VAL 386.A N ASP 382.A O no hydrogen 2.920 N/A ILE 387.A N ALA 383.A O no hydrogen 2.903 N/A ARG 388.A N LEU 384.A O no hydrogen 2.903 N/A CYS 389.A N CYS 385.A O no hydrogen 2.914 N/A CYS 389.A SG ALA 77.A O no hydrogen 3.627 N/A CYS 389.A SG CYS 385.A O no hydrogen 3.301 N/A LEU 390.A N VAL 386.A O no hydrogen 2.893 N/A VAL 391.A N ILE 387.A O no hydrogen 2.896 N/A LYS 392.A N ARG 388.A O no hydrogen 2.910 N/A ILE 397.A N GLN 485.A O no hydrogen 3.018 N/A ILE 405.A N GLY 401.A O no hydrogen 3.177 N/A GLU 406.A N ALA 402.A O no hydrogen 2.923 N/A LEU 407.A N PRO 403.A O no hydrogen 2.883 N/A ALA 408.A N GLU 404.A O no hydrogen 2.905 N/A LEU 409.A N ILE 405.A O no hydrogen 2.913 N/A ARG 410.A N GLU 406.A O no hydrogen 2.914 N/A ARG 410.A NH1 GLU 413.A OE2 no hydrogen 3.213 N/A ARG 410.A NH2 GLU 406.A OE1 no hydrogen 3.416 N/A LEU 411.A N LEU 407.A O no hydrogen 2.885 N/A THR 412.A N ALA 408.A O no hydrogen 2.902 N/A THR 412.A OG1 ALA 408.A O no hydrogen 2.815 N/A GLU 413.A N LEU 409.A O no hydrogen 2.929 N/A TYR 414.A N ARG 410.A O no hydrogen 2.891 N/A SER 415.A N LEU 411.A O no hydrogen 2.895 N/A SER 415.A OG SER 423.A O no hydrogen 3.187 N/A ARG 416.A N THR 412.A O no hydrogen 2.916 N/A THR 417.A N GLU 413.A O no hydrogen 2.907 N/A THR 417.A OG1 GLU 413.A O no hydrogen 2.781 N/A LEU 418.A N TYR 414.A O no hydrogen 2.664 N/A SER 423.A N GLY 420.A O no hydrogen 3.209 N/A SER 423.A OG LEU 418.A O no hydrogen 2.971 N/A SER 423.A OG GLY 420.A O no hydrogen 3.226 N/A VAL 426.A N GLU 422.A O no hydrogen 3.034 N/A ARG 427.A N SER 423.A O no hydrogen 2.789 N/A ALA 428.A N TYR 424.A O no hydrogen 3.126 N/A PHE 429.A N CYS 425.A O no hydrogen 3.415 N/A ALA 430.A N VAL 426.A O no hydrogen 3.134 N/A ASP 431.A N ARG 427.A O no hydrogen 3.132 N/A ASP 431.A N ALA 428.A O no hydrogen 2.919 N/A ALA 432.A N PHE 429.A O no hydrogen 2.918 N/A THR 439.A N VAL 435.A O no hydrogen 2.941 N/A THR 439.A OG1 VAL 435.A O no hydrogen 2.552 N/A LEU 440.A N ILE 436.A O no hydrogen 2.911 N/A ALA 441.A N PRO 437.A O no hydrogen 2.897 N/A GLU 442.A N SER 438.A O no hydrogen 2.905 N/A ASN 443.A N THR 439.A O no hydrogen 2.901 N/A ASN 443.A ND2 LEU 27.A O no hydrogen 3.312 N/A ALA 444.A N LEU 440.A O no hydrogen 2.903 N/A GLY 445.A N ALA 441.A O no hydrogen 3.363 N/A LEU 446.A N ALA 441.A O no hydrogen 3.337 N/A ASN 447.A ND2 SER 450.A OG no hydrogen 2.487 N/A THR 451.A N ASN 447.A O no hydrogen 3.219 N/A THR 451.A OG1 ASN 447.A O no hydrogen 2.420 N/A VAL 452.A N PRO 448.A O no hydrogen 2.900 N/A THR 453.A N ILE 449.A O no hydrogen 2.911 N/A THR 453.A OG1 ILE 449.A O no hydrogen 2.767 N/A GLU 454.A N SER 450.A O no hydrogen 2.899 N/A LEU 455.A N THR 451.A O no hydrogen 2.901 N/A ARG 456.A N VAL 452.A O no hydrogen 2.905 N/A ASN 457.A N THR 453.A O no hydrogen 2.902 N/A ARG 458.A N GLU 454.A O no hydrogen 2.906 N/A HIS 459.A N LEU 455.A O no hydrogen 2.897 N/A HIS 459.A ND1 GLU 463.A O no hydrogen 2.783 N/A ALA 460.A N ARG 456.A O no hydrogen 2.905 N/A GLN 461.A N ASN 457.A O no hydrogen 2.903 N/A GLY 462.A N ARG 458.A O no hydrogen 2.903 N/A ALA 466.A N THR 465.A OG1 no hydrogen 2.597 N/A ASN 469.A N GLY 474.A O no hydrogen 3.127 N/A VAL 470.A N ASN 469.A OD1 no hydrogen 2.750 N/A GLN 485.A N ILE 397.A O no hydrogen 2.940 N/A LEU 487.A N ALA 395.A O no hydrogen 3.439 N/A SER 490.A N LEU 487.A O no hydrogen 3.352 N/A VAL 491.A N LEU 487.A O no hydrogen 3.082 N/A SER 492.A N LEU 488.A O no hydrogen 2.909 N/A SER 492.A OG LEU 488.A O no hydrogen 3.139 N/A LEU 494.A N SER 490.A O no hydrogen 2.897 N/A THR 495.A N VAL 491.A O no hydrogen 2.931 N/A THR 495.A OG1 VAL 491.A O no hydrogen 2.982 N/A THR 495.A OG1 SER 492.A O no hydrogen 2.684 N/A LEU 496.A N SER 492.A O no hydrogen 2.901 N/A ALA 497.A N ALA 493.A O no hydrogen 2.903 N/A THR 498.A N LEU 494.A O no hydrogen 2.912 N/A THR 498.A OG1 LEU 494.A O no hydrogen 2.689 N/A GLU 499.A N THR 495.A O no hydrogen 2.909 N/A THR 500.A N LEU 496.A O no hydrogen 2.903 N/A THR 500.A OG1 LEU 496.A O no hydrogen 2.799 N/A VAL 501.A N ALA 497.A O no hydrogen 2.905 N/A ARG 502.A N THR 498.A O no hydrogen 2.909 N/A ARG 502.A NH1 GLN 113.A OE1 no hydrogen 2.673 N/A SER 503.A N GLU 499.A O no hydrogen 2.902 N/A ILE 504.A N THR 500.A O no hydrogen 2.900 N/A LEU 505.A N VAL 501.A O no hydrogen 2.901 N/A LYS 506.A N ARG 502.A O no hydrogen 2.908 N/A