Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8icq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 8.A N ASN 4.A O no hydrogen 3.031 N/A THR 8.A OG1 GLY 5.A O no hydrogen 2.648 N/A ASP 9.A N GLY 5.A O no hydrogen 2.637 N/A MET 10.A N GLY 6.A O no hydrogen 2.397 N/A LEU 11.A N ILE 7.A O no hydrogen 2.988 N/A THR 12.A N THR 8.A O no hydrogen 2.890 N/A THR 12.A OG1 THR 8.A O no hydrogen 2.998 N/A THR 12.A OG1 ASP 9.A O no hydrogen 3.565 N/A GLU 13.A N ASP 9.A O no hydrogen 2.945 N/A LEU 14.A N MET 10.A O no hydrogen 3.115 N/A ALA 15.A N LEU 11.A O no hydrogen 3.150 N/A ASN 16.A N THR 12.A O no hydrogen 3.011 N/A PHE 17.A N GLU 13.A O no hydrogen 2.918 N/A PHE 17.A N LEU 14.A O no hydrogen 3.012 N/A GLU 18.A N LEU 14.A O no hydrogen 3.037 N/A LYS 19.A N ALA 15.A O no hydrogen 3.178 N/A ASN 20.A N ASN 16.A O no hydrogen 3.457 N/A SER 22.A N GLU 18.A O no hydrogen 3.090 N/A SER 22.A OG PHE 17.A O no hydrogen 3.493 N/A SER 22.A OG GLU 18.A O no hydrogen 3.172 N/A SER 22.A OG GLU 18.A OE1 no hydrogen 3.508 N/A ALA 24.A N GLU 18.A O no hydrogen 3.443 N/A TYR 28.A N ALA 24.A O no hydrogen 2.799 N/A ASN 29.A N ILE 25.A O no hydrogen 2.599 N/A ALA 30.A N HIS 26.A O no hydrogen 2.545 N/A TYR 31.A N LYS 27.A O no hydrogen 2.961 N/A LYS 33.A N ASN 29.A O no hydrogen 3.328 N/A LYS 33.A NZ ALA 30.A O no hydrogen 3.111 N/A LYS 33.A NZ GLY 56.A O no hydrogen 2.335 N/A ALA 34.A N ALA 30.A O no hydrogen 3.024 N/A ALA 35.A N TYR 31.A O no hydrogen 2.765 N/A SER 36.A N ARG 32.A O no hydrogen 2.733 N/A VAL 37.A N LYS 33.A O no hydrogen 2.858 N/A ILE 38.A N ALA 34.A O no hydrogen 2.850 N/A LYS 40.A N VAL 37.A O no hydrogen 2.708 N/A TYR 41.A N VAL 37.A O no hydrogen 3.050 N/A TYR 41.A OH GLU 50.A OE2 no hydrogen 2.407 N/A LYS 44.A NZ LEU 3.A O no hydrogen 3.296 N/A LYS 46.A N GLU 50.A OE1 no hydrogen 2.750 N/A GLY 48.A N ASP 66.A OD1 no hydrogen 2.859 N/A ALA 51.A N SER 47.A O no hydrogen 3.028 N/A ALA 51.A N GLY 48.A O no hydrogen 2.558 N/A LYS 52.A N GLY 48.A O no hydrogen 2.812 N/A LYS 53.A N ALA 49.A O no hydrogen 3.246 N/A LEU 54.A N ALA 51.A O no hydrogen 2.546 N/A VAL 57.A N LEU 54.A O no hydrogen 3.316 N/A ALA 62.A N GLY 58.A O no hydrogen 2.809 N/A GLU 63.A N THR 59.A O no hydrogen 3.139 N/A ILE 65.A N ILE 61.A O no hydrogen 2.843 N/A ASP 66.A N ALA 62.A O no hydrogen 2.852 N/A GLU 67.A N GLU 63.A O no hydrogen 3.444 N/A PHE 68.A N LYS 64.A O no hydrogen 2.985 N/A LEU 69.A N ILE 65.A O no hydrogen 2.656 N/A ALA 70.A N ASP 66.A O no hydrogen 2.430 N/A THR 71.A N GLU 67.A O no hydrogen 2.781 N/A THR 71.A OG1 GLU 67.A O no hydrogen 3.570 N/A LYS 73.A N THR 71.A O no hydrogen 2.358 N/A LYS 73.A N THR 71.A OG1 no hydrogen 3.002 N/A LYS 73.A NZ GLU 78.A OE1 no hydrogen 3.460 N/A GLU 78.A N LEU 74.A O no hydrogen 2.871 N/A LYS 79.A N ARG 75.A O no hydrogen 2.560 N/A ILE 80.A N LYS 76.A O no hydrogen 3.036 N/A ARG 81.A N LEU 77.A O no hydrogen 3.117 N/A GLN 82.A N GLU 78.A O no hydrogen 3.269 N/A GLN 82.A N LYS 79.A O no hydrogen 3.058 N/A ASP 83.A N LYS 79.A O no hydrogen 3.044 N/A SER 86.A N ASP 83.A OD2 no hydrogen 3.424 N/A SER 87.A N ASP 83.A O no hydrogen 2.749 N/A SER 87.A OG ASP 83.A O no hydrogen 3.115 N/A SER 88.A N ASP 84.A O no hydrogen 2.679 N/A SER 88.A OG ASP 84.A O no hydrogen 3.029 N/A ILE 89.A N THR 85.A O no hydrogen 3.153 N/A ASN 90.A N SER 86.A O no hydrogen 3.489 N/A PHE 91.A N SER 87.A O no hydrogen 3.360 N/A LEU 92.A N SER 88.A O no hydrogen 2.898 N/A THR 93.A N ILE 89.A O no hydrogen 3.253 N/A ARG 94.A N PHE 91.A O no hydrogen 2.820 N/A ARG 94.A NE GLU 139.A OE2 no hydrogen 2.847 N/A ARG 94.A NH2 GLU 139.A OE1 no hydrogen 3.463 N/A ARG 94.A NH2 GLU 139.A OE2 no hydrogen 3.219 N/A VAL 95.A N LEU 92.A O no hydrogen 3.305 N/A SER 96.A OG HIS 127.A NE2 no hydrogen 3.023 N/A ILE 98.A N VAL 95.A O no hydrogen 2.804 N/A ALA 103.A N GLY 99.A O no hydrogen 2.865 N/A ARG 104.A N PRO 100.A O no hydrogen 2.699 N/A ARG 104.A NE PRO 100.A O no hydrogen 3.383 N/A LYS 105.A N SER 101.A O no hydrogen 3.307 N/A PHE 106.A N ALA 102.A O no hydrogen 2.681 N/A VAL 107.A N ALA 103.A O no hydrogen 3.196 N/A ASP 108.A N ARG 104.A O no hydrogen 2.801 N/A GLU 109.A N LYS 105.A O no hydrogen 2.967 N/A GLY 110.A N VAL 107.A O no hydrogen 2.736 N/A ILE 111.A N PHE 106.A O no hydrogen 2.586 N/A LYS 112.A N ASP 116.A OD2 no hydrogen 2.343 N/A THR 113.A N ASP 116.A OD2 no hydrogen 2.936 N/A ASP 116.A N THR 113.A OG1 no hydrogen 3.219 N/A LEU 117.A N THR 113.A O no hydrogen 2.942 N/A ARG 118.A N LEU 114.A O no hydrogen 3.153 N/A LYS 119.A N GLU 115.A O no hydrogen 3.070 N/A ASN 120.A N LEU 117.A O no hydrogen 3.251 N/A ASN 120.A ND2 ASP 116.A O no hydrogen 2.471 N/A GLU 121.A N ARG 118.A O no hydrogen 2.906 N/A LYS 123.A N ASN 120.A O no hydrogen 3.044 N/A LYS 123.A NZ ASN 120.A OD1 no hydrogen 3.505 N/A LEU 124.A N GLU 121.A O no hydrogen 3.103 N/A HIS 127.A NE2 SER 96.A OG no hydrogen 3.023 N/A ARG 129.A N ASN 125.A O no hydrogen 2.886 N/A ARG 129.A N HIS 126.A O no hydrogen 2.872 N/A ARG 129.A NE GLU 121.A O no hydrogen 2.869 N/A ILE 130.A N HIS 126.A O no hydrogen 2.934 N/A GLY 131.A N HIS 127.A O no hydrogen 2.823 N/A LEU 132.A N GLN 128.A O no hydrogen 3.027 N/A LYS 133.A N ARG 129.A O no hydrogen 2.948 N/A LYS 133.A NZ TYR 134.A OH no hydrogen 3.457 N/A LYS 133.A NZ ASP 218.A OD1 no hydrogen 3.545 N/A TYR 134.A N ILE 130.A O no hydrogen 2.772 N/A TYR 134.A OH ASP 218.A OD2 no hydrogen 2.969 N/A PHE 138.A N TYR 134.A O no hydrogen 2.633 N/A PHE 138.A N PHE 135.A O no hydrogen 3.265 N/A GLU 139.A N PHE 135.A O no hydrogen 3.363 N/A GLU 139.A N GLY 136.A O no hydrogen 2.746 N/A LYS 140.A NZ ASP 137.A OD1 no hydrogen 3.533 N/A ARG 141.A NH2 SER 179.A O no hydrogen 3.033 N/A ARG 141.A NH2 SER 179.A OG no hydrogen 3.292 N/A ILE 142.A N SER 180.A O no hydrogen 2.300 N/A ARG 144.A N GLU 178.A O no hydrogen 3.165 N/A ARG 144.A NH2 PHE 173.A O no hydrogen 2.535 N/A MET 147.A N PRO 143.A O no hydrogen 2.675 N/A LEU 148.A N ARG 144.A O no hydrogen 2.728 N/A MET 150.A N GLU 146.A O no hydrogen 2.886 N/A GLN 151.A N MET 147.A O no hydrogen 2.956 N/A ASP 152.A N LEU 148.A O no hydrogen 2.916 N/A ILE 153.A N GLN 149.A O no hydrogen 3.072 N/A VAL 154.A N MET 150.A O no hydrogen 2.994 N/A LEU 155.A N GLN 151.A O no hydrogen 3.207 N/A ASN 156.A N ASP 152.A O no hydrogen 3.280 N/A GLU 157.A N ILE 153.A O no hydrogen 3.178 N/A VAL 158.A N VAL 154.A O no hydrogen 3.147 N/A LYS 159.A N LEU 155.A O no hydrogen 2.969 N/A LYS 160.A N ASN 156.A O no hydrogen 2.898 N/A LYS 160.A NZ GLU 157.A OE1 no hydrogen 2.587 N/A VAL 161.A N GLU 157.A O no hydrogen 2.774 N/A ASP 162.A N VAL 158.A O no hydrogen 3.146 N/A GLU 164.A N ASP 162.A OD1 no hydrogen 2.564 N/A ILE 166.A N THR 188.A O no hydrogen 3.247 N/A THR 168.A N LEU 186.A O no hydrogen 3.065 N/A THR 168.A OG1 TYR 257.A OH no hydrogen 3.039 N/A CYS 170.A N ASP 184.A O no hydrogen 3.054 N/A CYS 170.A SG THR 168.A O no hydrogen 3.728 N/A ARG 174.A N GLY 171.A O no hydrogen 2.720 N/A ARG 174.A NH2 GLU 308.A OE1 no hydrogen 2.345 N/A ARG 175.A N GLY 171.A O no hydrogen 3.312 N/A ALA 177.A N SER 172.A O no hydrogen 2.803 N/A SER 180.A N ILE 142.A O no hydrogen 2.723 N/A MET 183.A N ARG 246.A O no hydrogen 3.103 N/A VAL 185.A N ASP 248.A O no hydrogen 2.906 N/A LEU 186.A N THR 168.A O no hydrogen 2.871 N/A LEU 187.A N ARG 250.A O no hydrogen 2.591 N/A THR 188.A N ILE 166.A O no hydrogen 3.124 N/A THR 188.A OG1 HIS 189.A O no hydrogen 3.278 N/A THR 188.A OG1 ILE 252.A O no hydrogen 2.286 N/A SER 191.A OG HIS 189.A ND1 no hydrogen 3.261 N/A PHE 192.A N HIS 189.A O no hydrogen 3.030 N/A THR 193.A N SER 196.A OG no hydrogen 2.899 N/A SER 194.A N ASP 255.A OD1 no hydrogen 2.663 N/A SER 194.A OG ASP 255.A OD1 no hydrogen 3.080 N/A SER 194.A OG ASP 255.A OD2 no hydrogen 3.035 N/A SER 196.A OG THR 193.A O no hydrogen 3.098 N/A SER 196.A OG SER 196.A O no hydrogen 2.283 N/A LEU 202.A N GLN 199.A O no hydrogen 2.937 N/A LEU 203.A N PRO 200.A O no hydrogen 2.977 N/A HIS 204.A N PRO 200.A O no hydrogen 3.293 N/A HIS 204.A NE2 GLY 223.A O no hydrogen 3.347 N/A GLN 205.A N LYS 201.A O no hydrogen 2.511 N/A VAL 207.A N LEU 203.A O no hydrogen 3.089 N/A GLU 208.A N HIS 204.A O no hydrogen 2.956 N/A GLN 209.A N GLN 205.A O no hydrogen 3.158 N/A LEU 210.A N VAL 206.A O no hydrogen 3.045 N/A GLN 211.A N VAL 207.A O no hydrogen 2.915 N/A LYS 212.A N GLU 208.A O no hydrogen 2.772 N/A VAL 213.A N GLN 209.A O no hydrogen 3.016 N/A HIS 214.A N GLN 211.A O no hydrogen 2.593 N/A PHE 215.A N LEU 210.A O no hydrogen 2.868 N/A ILE 216.A N LEU 210.A O no hydrogen 3.299 N/A THR 217.A N VAL 230.A O no hydrogen 2.729 N/A THR 217.A OG1 ASP 218.A OD2 no hydrogen 3.136 N/A THR 217.A OG1 VAL 230.A O no hydrogen 3.446 N/A LEU 220.A N MET 228.A O no hydrogen 2.760 N/A SER 221.A N MET 228.A O no hydrogen 2.930 N/A GLY 223.A N LYS 226.A O no hydrogen 3.177 N/A PHE 227.A N ILE 249.A O no hydrogen 3.012 N/A MET 228.A N SER 221.A O no hydrogen 2.521 N/A GLY 229.A N ILE 247.A O no hydrogen 2.654 N/A VAL 230.A N ASP 218.A O no hydrogen 3.216 N/A CYS 231.A N ARG 245.A O no hydrogen 2.743 N/A CYS 231.A SG ARG 245.A O no hydrogen 3.869 N/A GLN 232.A N PHE 215.A O no hydrogen 2.914 N/A GLN 232.A NE2 GLU 241.A OE2 no hydrogen 2.551 N/A GLN 232.A NE2 TYR 242.A O no hydrogen 2.590 N/A SER 235.A OG LEU 233.A O no hydrogen 3.222 N/A ASP 238.A N LYS 236.A O no hydrogen 2.842 N/A TYR 242.A N SER 235.A OG no hydrogen 3.374 N/A HIS 244.A N ASP 137.A OD2 no hydrogen 2.280 N/A HIS 244.A ND1 ASP 137.A OD2 no hydrogen 3.050 N/A ARG 245.A N CYS 231.A O no hydrogen 2.870 N/A ARG 245.A NE GLU 146.A OE1 no hydrogen 2.920 N/A ARG 245.A NH1 LYS 140.A O no hydrogen 3.432 N/A ARG 245.A NH2 ARG 141.A O no hydrogen 3.124 N/A ARG 245.A NH2 GLU 146.A OE1 no hydrogen 2.954 N/A ARG 246.A NH1 ILE 247.A O no hydrogen 2.936 N/A ARG 246.A NH1 ASP 248.A OD1 no hydrogen 3.056 N/A ARG 246.A NH2 ASP 248.A OD1 no hydrogen 2.371 N/A ILE 247.A N GLY 229.A O no hydrogen 2.958 N/A ASP 248.A N MET 183.A O no hydrogen 2.942 N/A ILE 249.A N PHE 227.A O no hydrogen 3.163 N/A ARG 250.A N VAL 185.A O no hydrogen 3.169 N/A LEU 251.A N THR 225.A O no hydrogen 2.691 N/A LYS 254.A N PHE 192.A O no hydrogen 2.519 N/A GLN 256.A N PRO 253.A O no hydrogen 2.651 N/A GLN 256.A NE2 TYR 288.A O no hydrogen 3.073 N/A TYR 257.A OH THR 168.A OG1 no hydrogen 3.039 N/A TYR 257.A OH LEU 186.A O no hydrogen 2.306 N/A GLY 260.A N GLN 256.A O no hydrogen 3.271 N/A VAL 261.A N TYR 257.A O no hydrogen 2.521 N/A LEU 262.A N TYR 258.A O no hydrogen 2.400 N/A TYR 263.A N CYS 259.A O no hydrogen 2.722 N/A PHE 264.A N GLY 260.A O no hydrogen 2.891 N/A THR 265.A N VAL 261.A O no hydrogen 3.306 N/A THR 265.A N LEU 262.A O no hydrogen 3.073 N/A THR 265.A OG1 VAL 261.A O no hydrogen 2.421 N/A THR 265.A OG1 LEU 262.A O no hydrogen 3.461 N/A SER 267.A N ARG 325.A O no hydrogen 2.986 N/A SER 267.A OG SER 326.A O no hydrogen 3.286 N/A ILE 269.A N SER 267.A OG no hydrogen 3.104 N/A PHE 270.A N SER 267.A OG no hydrogen 3.250 N/A ASN 271.A N SER 267.A O no hydrogen 3.015 N/A LYS 272.A N ASP 268.A O no hydrogen 3.407 N/A ASN 273.A N ILE 269.A O no hydrogen 2.792 N/A MET 274.A N PHE 270.A O no hydrogen 2.877 N/A ARG 275.A N ASN 271.A O no hydrogen 2.331 N/A ALA 276.A N LYS 272.A O no hydrogen 2.346 N/A HIS 277.A N ASN 273.A O no hydrogen 2.940 N/A HIS 277.A NE2 ILE 315.A O no hydrogen 2.705 N/A ALA 278.A N MET 274.A O no hydrogen 3.036 N/A GLU 280.A N HIS 277.A O no hydrogen 3.025 N/A LYS 281.A N HIS 277.A O no hydrogen 2.998 N/A PHE 283.A N ALA 278.A O no hydrogen 2.611 N/A ASN 286.A N THR 289.A O no hydrogen 3.196 N/A ASN 286.A ND2 THR 289.A O no hydrogen 3.239 N/A ASN 286.A ND2 THR 289.A OG1 no hydrogen 2.693 N/A GLU 287.A N GLU 287.A OE1 no hydrogen 2.270 N/A ARG 291.A N THR 284.A O no hydrogen 2.841 N/A LEU 293.A N GLY 282.A O no hydrogen 2.826 N/A THR 296.A OG1 VAL 298.A O no hydrogen 3.043 N/A LEU 303.A N ILE 290.A O no hydrogen 2.758 N/A ASP 306.A N ASP 310.A OD2 no hydrogen 3.081 N/A PHE 312.A N GLU 308.A O no hydrogen 3.281 N/A ASP 313.A N LYS 309.A O no hydrogen 2.694 N/A TYR 314.A N ASP 310.A O no hydrogen 3.060 N/A TYR 314.A OH PRO 304.A O no hydrogen 2.287 N/A ILE 315.A N ILE 311.A O no hydrogen 3.117 N/A GLN 316.A N ASP 313.A O no hydrogen 2.556 N/A TRP 317.A N PHE 312.A O no hydrogen 2.907 N/A ARG 320.A NH1 GLU 327.A OXT no hydrogen 2.969 N/A ASP 324.A N GLU 321.A O no hydrogen 2.951 N/A ARG 325.A N PRO 322.A O no hydrogen 2.731 N/A ARG 325.A NE ARG 320.A O no hydrogen 2.272 N/A ARG 325.A NH1 GLU 308.A OE2 no hydrogen 3.278 N/A ARG 325.A NH2 GLU 308.A OE1 no hydrogen 3.053 N/A ARG 325.A NH2 ARG 320.A O no hydrogen 2.832 N/A